Hub : Genes

Plekhm3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC intron excision ratio chr9_73799503_73814060 0.06 0.05 7.4e-03 0.03 0.03 0.02 0.03 3.0e-02 1.5e-02 4.4e-02 1.7e-02
2 PL gene expression Plekhm3 0.03 0.02 1.1e-03 0.01 0.02 0.01 0.02 1.0e-02 2.8e-03 1.7e-02 4.7e-03
3 NAcc alternative TSS XM_039084592.2 0.02 0.01 3.3e-04 0.02 0.02 0.01 0.01 1.4e-03 3.8e-04 2.3e-03 2.5e-03
4 Brain alternative polyA XM_017596816.3 0.06 0.04 1.9e-06 0.07 0.07 0.08 0.07 4.1e-07 5.7e-07 1.5e-07 3.9e-07
5 BLA gene expression Plekhm3 0.05 0.04 4.7e-03 0.04 0.03 0.02 0.02 3.8e-03 1.4e-02 3.1e-02 1.8e-02
6 Brain alternative polyA XM_017596816.3 0.06 0.04 1.5e-06 0.07 0.07 0.08 0.07 2.5e-07 4.5e-07 8.9e-08 2.4e-07
7 Brain alternative polyA XM_063267901.1 0.06 0.04 2.3e-07 0.09 0.08 0.08 0.08 1.7e-08 9.7e-08 5.0e-08 8.0e-08
8 Brain alternative polyA XM_063267901.1 0.06 0.04 1.6e-07 0.09 0.08 0.09 0.08 9.6e-09 7.2e-08 1.2e-08 4.7e-08
9 Brain gene expression Plekhm3 0.03 0.02 4.7e-04 0.04 0.04 0.04 0.04 1.7e-04 2.0e-04 1.5e-04 2.5e-04
10 IC gene expression Plekhm3 0.07 0.06 2.3e-03 0.02 0.01 0.01 0 7.0e-02 7.4e-02 9.4e-02 2.6e-01
11 NAcc alternative TSS XM_017596820.3 0.01 0.01 8.4e-03 0.01 0.01 0.01 0.01 1.5e-02 2.1e-02 1.3e-02 2.4e-02
12 pVTA gene expression Plekhm3 0.09 0.08 7.7e-06 0.06 0.07 0.06 0.07 1.1e-05 3.7e-06 9.4e-06 3.6e-06
13 NAcc gene expression Plekhm3 0.06 0.04 5.8e-12 0.06 0.07 0.06 0.06 2.4e-09 1.8e-10 7.6e-10 5.2e-09
14 NAcc alternative polyA XM_063267901.1 0.02 0.01 2.2e-03 0.01 0.01 0.01 0.01 5.6e-03 4.4e-03 5.3e-03 8.2e-03
15 NAcc alternative polyA XM_017596816.3 0.02 0.02 7.5e-04 0.01 0.01 0.01 0.01 2.3e-03 2.1e-03 3.0e-03 6.5e-03
16 NAcc alternative polyA XM_063267901.1 0.02 0.01 1.6e-03 0.01 0.01 0.01 0.01 4.3e-03 4.4e-03 4.0e-03 6.9e-03
17 Brain mRNA stability Plekhm3 0.04 0.03 4.8e-04 0.03 0.03 0.02 0.03 1.1e-03 1.6e-03 2.7e-03 7.9e-04
18 NAcc alternative polyA XM_017596816.3 0.02 0.02 1.2e-03 0.01 0.01 0.01 0.01 2.8e-03 2.3e-03 2.8e-03 4.5e-03
19 NAcc alternative TSS XM_006245080.5 0.03 0.02 3.0e-03 0.01 0.01 0.01 0.01 3.5e-03 1.5e-02 1.6e-02 6.0e-03
20 pVTA alternative polyA XM_063267901.1 0.03 0.03 8.9e-03 0.01 0.03 0.03 0.02 1.9e-02 2.0e-03 3.0e-03 1.7e-02
21 pVTA alternative polyA XM_017596816.3 0.03 0.03 7.8e-03 0.02 0.03 0.03 0.02 1.6e-02 1.5e-03 1.7e-03 1.2e-02
22 pVTA alternative polyA XM_063267901.1 0.04 0.04 5.5e-03 0.02 0.03 0.03 0.02 1.2e-02 9.8e-04 1.4e-03 8.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.10.10.20.5-0.50.4-0.2-0.3-0.20.20.2-0.2-0.3-0.4-0.5-0.30.3-0.30.4-0.3-0.20.30.1-0.10.1
Area under the delay curve0.10.20.6-0.80.7-0.60.50.40.5-0.4-0.40.50.40.40.40.3-0.30.2-0.40.30.2-0.40.0-0.10.1
BMI with tail8.328.833.9-5.65.5-5.65.65.45.5-5.4-5.45.55.85.45.25.4-5.45.3-5.25.15.3-5.4-5.04.9-4.9
BMI without tail2.98.810.4-3.23.2-3.23.02.92.9-2.9-2.93.03.23.23.03.0-3.02.9-2.93.02.9-3.2-2.62.6-2.5
Body weight0.10.61.6-1.21.1-1.10.70.70.7-0.6-0.60.71.30.90.80.8-0.80.7-0.70.80.7-0.9-0.50.5-0.4
Weight adjusted by age0.40.51.61.1-1.11.0-0.2-0.5-0.20.20.2-0.3-0.5-1.0-1.2-0.50.7-0.71.0-1.3-0.70.80.4-0.30.3
Bone surface0.20.41.00.7-0.80.7-0.4-0.4-0.30.30.3-0.4-0.4-0.7-0.9-0.50.6-0.60.9-0.8-0.61.00.4-0.40.4
Bone volume0.71.32.11.4-1.41.3-1.1-1.1-1.11.11.1-1.1-1.1-1.2-1.3-1.11.1-1.11.3-1.2-1.01.20.8-0.80.7
Breakpoint value in progressive ratio session1.72.03.71.8-1.81.7-1.1-1.2-1.00.90.9-1.1-1.4-1.7-1.9-1.31.4-1.41.6-1.8-1.41.81.0-1.01.0
Number of licking bursts0.20.30.6-0.20.2-0.30.50.60.5-0.6-0.60.60.30.50.30.5-0.50.6-0.60.70.6-0.4-0.80.8-0.8
Context. condit. distance diff. score0.91.12.0-0.60.8-0.80.80.80.8-0.8-0.80.90.71.11.21.0-1.11.2-1.21.31.2-1.2-1.41.4-1.4
Locomotion velocity, session 11.71.93.60.8-0.91.0-1.2-1.1-1.21.21.2-1.2-1.3-1.3-1.4-1.41.5-1.51.4-1.2-1.51.21.9-1.91.9
Locomotion distance, session 10.20.20.9-0.40.1-0.10.30.30.3-0.4-0.40.2-0.3-0.4-0.6-0.30.4-0.50.5-0.4-0.50.30.9-0.91.0
Locomotion velocity, session 20.20.20.6-0.50.2-0.20.40.30.4-0.5-0.50.30.1-0.3-0.4-0.10.3-0.30.3-0.5-0.40.50.7-0.70.8
Locomotion distance, session 20.20.30.8-0.90.7-0.60.80.80.8-0.9-0.90.70.30.10.00.3-0.10.1-0.10.00.0-0.10.3-0.40.4
Locomotion velocity, session 30.60.70.9-0.70.8-0.80.80.80.8-0.7-0.70.80.80.80.70.9-0.90.9-0.80.80.9-0.7-0.90.9-0.9
Locomotion distance, session 31.41.52.31.5-1.41.4-1.3-1.1-1.21.21.2-1.3-1.4-1.4-1.3-1.21.2-1.21.2-1.3-1.11.50.9-0.90.9
Stereotopy head waving bouts, day 32.22.63.5-1.91.8-1.81.71.71.7-1.6-1.61.61.71.61.51.6-1.61.6-1.61.51.5-1.4-1.31.3-1.3
Stereotopy head waving duration, day 32.53.04.4-2.12.0-2.01.91.81.9-1.9-1.91.92.01.71.51.7-1.61.6-1.51.61.5-1.5-1.31.2-1.2
Locomotion velocity, session 70.00.00.0-0.00.0-0.00.10.10.1-0.1-0.10.10.10.1-0.10.1-0.10.1-0.00.10.1-0.2-0.10.1-0.1
Locomotion distance, session 70.30.40.80.5-0.60.6-0.3-0.3-0.30.20.2-0.3-0.6-0.8-0.9-0.60.7-0.80.8-0.9-0.80.90.8-0.80.8
Stereotopy head waving bouts, day 70.20.20.4-0.40.5-0.50.30.40.3-0.3-0.30.40.40.60.60.5-0.50.5-0.60.60.6-0.5-0.60.6-0.6
Stereotopy head waving duration, day 72.22.73.2-1.51.6-1.61.51.51.5-1.5-1.51.51.61.71.71.7-1.71.7-1.71.81.7-1.7-1.81.8-1.8
Locomotion velocity, session 80.10.20.4-0.20.3-0.30.50.40.5-0.5-0.50.50.20.30.20.4-0.40.4-0.30.40.4-0.6-0.50.5-0.5
Locomotion distance, session 80.30.40.7-0.60.6-0.60.70.80.8-0.8-0.80.80.30.60.50.6-0.60.6-0.60.70.6-0.7-0.60.6-0.6
Degree of sensitization distance0.40.51.1-1.10.9-0.90.90.80.9-0.9-0.90.90.80.60.40.5-0.50.4-0.50.40.4-0.7-0.10.00.0
Degree of sensitization stereotypy0.70.81.2-0.70.8-0.80.70.70.7-0.7-0.70.70.71.01.10.9-0.91.0-1.11.01.0-0.9-1.01.0-1.0
Conditioned locomotion1.11.32.40.7-0.91.0-0.8-0.8-0.80.70.7-0.8-1.1-1.2-1.3-1.21.3-1.31.3-1.3-1.40.71.5-1.51.6
Cocaine response after cond. corrected1.31.63.50.5-0.70.9-1.0-1.0-1.01.01.0-1.1-1.1-1.2-1.1-1.31.4-1.41.3-1.4-1.51.51.8-1.81.9
Cocaine response after cond. not corrected1.82.23.60.9-1.11.2-1.4-1.4-1.41.31.3-1.4-1.4-1.4-1.3-1.61.5-1.61.4-1.4-1.61.61.9-1.91.9
Cocaine response before conditioning0.10.10.50.6-0.40.4-0.4-0.4-0.40.40.4-0.3-0.30.10.20.0-0.10.2-0.20.40.3-0.2-0.60.6-0.7
Saline control response0.40.61.3-1.11.0-1.00.90.90.9-0.9-0.90.90.90.60.70.7-0.60.5-0.60.40.5-1.1-0.20.2-0.2
Bone: connectivity density0.71.11.6-0.90.9-1.01.21.11.2-1.3-1.31.21.21.00.81.1-1.01.0-0.80.81.0-0.8-1.01.1-1.0
Bone: cortical apparent density1.72.33.3-1.61.5-1.61.71.81.7-1.8-1.81.71.71.41.11.6-1.51.5-1.41.11.5-1.3-1.41.4-1.4
Bone: cortical area0.60.91.61.3-1.21.2-0.9-1.0-0.90.90.9-0.9-0.9-1.0-1.0-0.90.9-0.91.0-1.0-0.80.80.6-0.50.5
Bone: cortical porosity8.69.311.63.3-3.23.2-3.4-3.3-3.43.33.3-3.3-3.3-2.9-2.8-3.13.0-2.92.9-2.7-2.92.42.7-2.72.6
Bone: cortical porosity10.111.013.63.6-3.43.5-3.7-3.6-3.73.63.6-3.6-3.6-3.2-3.1-3.43.3-3.23.2-2.9-3.22.62.9-2.92.9
Bone: cortical thickness0.20.30.60.7-0.70.7-0.4-0.4-0.40.40.4-0.4-0.4-0.6-0.8-0.40.5-0.40.7-0.6-0.40.60.2-0.20.2
Bone: cortical thickness1.31.53.71.3-1.41.3-1.0-1.0-1.00.90.9-1.1-1.0-1.4-1.6-1.11.2-1.21.5-1.5-1.21.91.1-1.01.1
Bone: cortical tissue density2.02.73.7-1.71.6-1.71.91.91.9-1.9-1.91.81.81.51.31.7-1.61.6-1.51.31.6-1.4-1.51.5-1.5
Condit. Reinf. active minus inactive responses1.11.32.01.4-1.31.3-1.2-1.2-1.21.21.2-1.2-1.2-1.2-1.1-1.11.1-1.01.1-1.1-1.01.20.8-0.80.7
Condit. Reinf. active-inactive response ratio0.10.10.40.6-0.50.5-0.5-0.5-0.50.50.5-0.5-0.4-0.3-0.2-0.30.2-0.20.2-0.2-0.20.30.0-0.0-0.0
Condit. Reinf. active responses1.82.23.21.8-1.81.7-1.5-1.5-1.51.51.5-1.5-1.4-1.6-1.6-1.41.4-1.41.6-1.6-1.41.61.1-1.01.0
Condit. Reinf. inactive responses1.11.42.21.2-1.21.2-1.0-1.0-1.01.01.0-1.1-0.9-1.3-1.4-1.11.2-1.21.4-1.5-1.21.41.1-1.11.1
Incentive salience index mean1.31.62.71.6-1.61.5-1.3-1.3-1.31.21.2-1.3-1.2-1.4-1.4-1.21.2-1.21.3-1.4-1.11.40.8-0.80.8
Condit. Reinf. lever presses0.81.11.91.4-1.41.2-0.8-0.9-0.80.80.8-0.9-0.8-1.2-1.4-0.81.0-0.91.2-1.4-0.91.40.6-0.50.5
Condit. Reinf. active minus inactive responses7.910.311.13.0-3.13.2-3.2-3.2-3.23.13.1-3.2-3.1-3.2-3.1-3.33.3-3.33.2-3.2-3.33.13.3-3.33.3
Condit. Reinf. active-inactive response ratio6.87.98.52.8-2.82.8-2.8-2.9-2.82.82.8-2.8-2.8-2.8-2.7-2.92.9-2.92.8-2.7-2.92.62.8-2.82.8
Condit. Reinf. active responses5.27.28.12.6-2.62.7-2.6-2.6-2.62.62.6-2.6-2.7-2.8-2.6-2.82.8-2.82.7-2.8-2.82.62.8-2.82.8
Condit. Reinf. inactive responses0.20.30.60.5-0.50.5-0.5-0.4-0.50.50.5-0.5-0.5-0.6-0.4-0.50.6-0.60.5-0.7-0.60.70.5-0.50.5
Condit. Reinf. lever presses1.21.62.11.2-1.21.3-1.1-1.2-1.11.11.1-1.1-1.3-1.3-1.3-1.31.4-1.41.3-1.3-1.41.11.4-1.41.4
Condit. Reinf. lever reinforcers received5.57.78.42.6-2.72.8-2.7-2.7-2.72.72.7-2.7-2.8-2.8-2.7-2.92.9-2.92.8-2.9-2.92.62.9-2.92.9
Conditioned reinforcement - actives1.01.82.6-1.41.4-1.41.31.51.3-1.2-1.21.31.41.41.61.4-1.31.3-1.21.21.3-1.4-1.21.2-1.2
Conditioned reinforcement - inactives1.42.13.21.3-1.41.4-1.4-1.3-1.41.41.4-1.5-1.3-1.7-1.0-1.41.5-1.51.6-1.6-1.51.81.5-1.51.5
Conditioned locomotion6.17.910.6-2.72.6-2.82.93.32.9-2.8-2.82.83.22.62.73.1-2.92.9-2.42.32.8-2.2-2.92.9-2.9
Patch foraging indifference point 0 sec0.71.22.1-1.31.3-1.31.00.90.9-0.9-0.91.01.01.21.21.0-1.11.1-1.21.41.1-1.4-0.90.8-0.8
Patch foraging indifference point AUC0.91.32.71.0-1.21.1-0.8-0.6-0.90.80.8-1.0-0.7-1.4-1.6-0.91.1-1.11.5-1.6-1.11.61.0-1.01.0
Delay disc. indifference point, 0s delay1.71.92.4-1.51.5-1.51.51.51.5-1.5-1.51.51.51.31.41.4-1.41.3-1.41.21.3-1.2-1.21.2-1.1
Delay disc. indifference point, 16s delay0.00.00.10.0-0.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.3-0.2-0.20.2-0.20.2-0.4-0.30.20.3-0.30.4
Delay disc. indifference point, 2s delay1.71.92.3-1.51.5-1.51.41.31.4-1.4-1.41.41.41.41.51.4-1.41.4-1.51.31.4-1.5-1.21.2-1.2
Delay disc. indifference point, 24s delay0.20.20.4-0.50.5-0.50.40.40.4-0.4-0.40.50.40.40.50.4-0.40.4-0.50.30.4-0.6-0.40.4-0.4
Delay disc. indifference point, 4s delay1.51.52.9-1.71.6-1.51.41.31.4-1.4-1.41.41.41.21.21.1-1.11.1-1.21.11.0-1.3-0.70.6-0.6
Delay disc. indifference point, 8s delay0.00.00.2-0.20.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.0-0.20.2-0.20.1-0.2-0.20.10.4-0.50.5
Indifference point function ln k1.72.95.6-1.71.9-1.81.61.31.6-1.5-1.51.71.41.92.21.5-1.71.7-2.02.11.7-2.4-1.51.4-1.4
Indifference point function log k1.72.95.6-1.71.9-1.81.61.31.6-1.5-1.51.71.41.92.21.5-1.71.7-2.02.11.7-2.4-1.51.4-1.4
Patch foraging total patch changes 0 sec0.51.02.1-1.21.2-1.10.80.80.8-0.8-0.80.90.91.11.20.9-1.01.0-1.11.31.0-1.4-0.80.8-0.8
Patch foraging total patch changes 12 sec0.10.10.50.7-0.70.5-0.1-0.1-0.10.10.1-0.2-0.1-0.5-0.7-0.10.2-0.20.5-0.6-0.20.3-0.10.2-0.2
Patch foraging total patch changes 18 sec0.30.40.7-0.80.7-0.70.70.80.7-0.8-0.80.70.80.50.50.7-0.60.6-0.40.40.6-0.2-0.50.5-0.5
Patch foraging total patch changes 24 sec0.10.11.20.2-0.30.2-0.10.0-0.1-0.1-0.1-0.2-0.1-0.4-0.3-0.10.2-0.30.5-0.5-0.31.10.2-0.20.2
Patch foraging total patch changes 6 sec0.81.22.1-1.31.3-1.31.11.31.1-1.0-1.01.11.21.10.91.2-1.11.1-1.01.01.1-1.4-0.90.9-0.9
Patch foraging time to switch 0 sec0.00.00.20.1-0.10.1-0.3-0.2-0.30.40.4-0.3-0.2-0.0-0.1-0.20.2-0.20.1-0.0-0.2-0.10.2-0.20.2
Patch foraging water rate 0 sec0.10.20.6-0.20.2-0.20.60.50.7-0.8-0.80.60.30.20.20.4-0.30.3-0.30.20.30.1-0.40.4-0.4
Patch foraging water rate 12 sec0.30.51.1-0.90.9-0.80.60.50.6-0.7-0.70.70.60.91.00.6-0.70.7-0.91.00.7-0.7-0.50.4-0.4
Patch foraging water rate 18 sec0.30.41.00.9-0.70.8-0.8-1.0-0.80.80.8-0.7-0.9-0.5-0.4-0.80.6-0.60.4-0.2-0.6-0.10.5-0.50.5
Patch foraging water rate 24 sec0.10.10.5-0.20.3-0.2-0.1-0.1-0.1-0.0-0.00.0-0.20.40.5-0.1-0.10.1-0.50.70.1-0.30.1-0.10.1
Patch foraging water rate 6 sec1.82.63.8-1.71.7-1.71.81.61.8-2.0-2.01.81.51.61.61.5-1.51.5-1.61.71.5-1.5-1.31.3-1.3
Seeking ratio, delayed vs. immediate footshock0.60.71.40.8-0.90.9-0.7-0.6-0.70.70.7-0.8-0.6-1.1-1.1-0.80.9-0.91.1-1.2-0.90.80.9-0.90.9
Distance traveled before self-admin2.53.34.91.9-2.01.9-1.6-1.7-1.61.61.6-1.6-1.6-2.0-2.1-1.81.9-1.92.1-2.2-1.91.61.8-1.71.8
Distance traveled after self-admin0.10.10.40.5-0.50.30.30.20.3-0.4-0.40.30.1-0.2-0.30.2-0.10.20.1-0.40.20.3-0.60.6-0.6
Extensor digitorum longus weight2.18.310.6-3.33.1-3.13.13.13.1-3.0-3.03.03.12.92.82.9-2.82.8-2.62.72.7-2.6-2.42.4-2.3
Bone: elastic displacement0.10.20.3-0.20.2-0.20.40.30.4-0.3-0.30.40.30.30.40.4-0.40.4-0.50.20.4-0.5-0.50.5-0.6
Bone: elastic work0.30.41.31.1-1.00.9-0.6-0.8-0.70.70.7-0.6-0.8-0.6-0.5-0.50.5-0.40.4-0.6-0.4-0.00.1-0.00.0
Bone: endosteal estimation1.53.34.52.1-2.12.0-1.9-1.9-1.91.91.9-1.9-1.9-1.9-1.6-1.81.8-1.81.7-1.9-1.71.51.5-1.41.4
Bone: endosteal perimeter0.40.91.41.2-1.11.1-1.2-1.1-1.21.21.2-1.1-1.1-0.8-0.6-0.90.9-0.80.7-0.7-0.80.30.6-0.60.6
Epididymis fat weight0.20.50.8-0.60.6-0.70.60.50.6-0.6-0.60.60.70.80.80.7-0.80.8-0.80.80.8-0.8-0.90.9-0.9
Delta time in closed arm before/after self-admin1.11.01.8-1.31.2-1.21.11.11.1-1.1-1.11.11.01.01.10.9-0.90.9-0.90.90.8-0.8-0.60.6-0.5
Delta time in open arm before/after self-admin5.55.46.12.4-2.52.4-2.3-2.2-2.32.32.3-2.4-2.3-2.5-2.4-2.32.3-2.32.4-2.4-2.32.42.1-2.12.1
Diff in mean of infusions in LGA sessions0.50.61.0-0.50.6-0.60.90.81.0-1.0-1.00.90.60.70.60.8-0.80.8-0.80.70.8-0.6-0.90.9-0.9
Delay discount exponential model param0.10.20.50.7-0.60.6-0.4-0.4-0.40.40.4-0.4-0.4-0.3-0.4-0.30.3-0.20.4-0.2-0.20.4-0.00.1-0.1
Extinction: sum of active levers before priming0.20.20.90.2-0.1-0.00.50.50.5-0.5-0.50.50.40.20.00.6-0.50.5-0.20.00.5-0.1-0.90.9-0.9
Active lever presses in extinction session 60.60.61.20.9-0.90.9-0.5-0.5-0.50.40.4-0.5-0.9-1.0-1.1-0.80.8-0.80.9-0.9-0.81.10.7-0.70.7
Bone: final force1.62.64.42.1-2.01.9-1.7-1.7-1.71.71.7-1.7-1.7-1.6-1.7-1.51.5-1.41.6-1.4-1.41.61.0-1.01.0
Bone: final moment1.11.83.11.8-1.61.6-1.5-1.5-1.51.51.5-1.5-1.5-1.3-1.3-1.31.2-1.21.3-1.0-1.21.30.9-0.80.8
Food consumed during 24 hour testing period0.70.91.40.7-0.80.8-0.8-0.8-0.80.90.9-0.9-0.8-1.0-0.9-1.01.0-1.01.1-1.0-1.10.91.1-1.21.2
Glucose0.71.11.5-1.01.0-1.01.21.21.2-1.1-1.11.21.10.90.91.1-1.11.1-0.90.91.0-0.8-1.01.0-1.0
Heart weight0.40.61.40.7-0.60.7-1.1-1.1-1.11.21.2-1.0-0.9-0.4-0.1-0.80.6-0.60.3-0.2-0.60.10.6-0.60.6
Delay discount hyperbolic model param0.20.20.70.9-0.80.7-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.5-0.40.4-0.30.5-0.4-0.30.50.1-0.00.0
Intermittent access intake day 1-15 change0.20.30.6-0.80.7-0.70.40.70.4-0.3-0.30.40.70.60.80.6-0.60.6-0.50.70.6-0.4-0.50.5-0.5
Intermittent access intake escalation0.10.20.6-0.60.6-0.60.20.50.2-0.2-0.20.20.40.50.60.4-0.50.5-0.40.80.5-0.3-0.40.4-0.4
Intermittent access intake escalation 20.20.20.5-0.70.6-0.60.50.70.5-0.5-0.50.40.60.40.20.5-0.50.5-0.30.60.50.2-0.30.3-0.3
Intermitt. access day 1 inactive lever presses0.10.20.8-0.10.2-0.2-0.00.1-0.00.10.10.10.10.50.90.3-0.50.5-0.70.70.5-0.9-0.60.6-0.7
Intermitt. access day 15 inactive lever presses0.10.20.30.5-0.40.4-0.6-0.5-0.60.60.6-0.5-0.5-0.40.1-0.40.3-0.30.3-0.2-0.30.20.2-0.20.2
Intermitt. access escalation Index0.50.71.4-0.40.4-0.51.01.01.0-1.0-1.00.91.00.4-0.21.0-0.80.8-0.40.30.9-0.4-1.11.2-1.2
Intermittent access day 1 total infusions0.00.10.20.2-0.20.2-0.1-0.1-0.10.10.1-0.2-0.1-0.4-0.2-0.20.3-0.30.5-0.5-0.30.20.3-0.30.3
Intermittent access day 15 total infusions0.50.71.1-0.90.9-0.90.81.00.8-0.8-0.80.81.00.71.10.9-0.90.9-0.60.80.8-0.9-0.80.8-0.8
Intermittent access terminal intake (last 3 days)1.31.72.0-1.31.3-1.31.31.41.2-1.2-1.21.31.41.31.41.3-1.31.3-1.11.31.3-1.4-1.31.3-1.3
Intermittent access total infusions0.40.50.8-0.70.6-0.70.80.90.8-0.8-0.80.80.90.50.70.7-0.60.6-0.40.40.6-0.7-0.60.6-0.6
Intermittent access day 1 locomotion0.20.20.6-0.10.1-0.20.50.60.5-0.5-0.50.40.60.20.40.6-0.50.5-0.20.00.5-0.0-0.70.8-0.8
Intermittent access day 15 total locomotion0.81.52.2-1.01.0-1.11.21.41.2-1.1-1.11.11.41.01.51.4-1.31.3-1.00.91.3-0.8-1.41.5-1.5
Intermittent access total locomotion3.33.95.5-1.91.8-1.92.02.32.0-2.0-2.01.92.31.82.12.2-2.02.0-1.61.42.0-1.5-2.12.1-2.1
Intermittent access standard deviation0.10.10.40.2-0.20.2-0.4-0.3-0.40.40.4-0.5-0.3-0.3-0.0-0.40.3-0.30.4-0.1-0.30.70.4-0.40.4
Left kidney weight0.52.23.6-1.71.7-1.71.51.41.4-1.2-1.21.31.91.71.31.6-1.61.5-1.41.51.5-1.3-1.41.4-1.4
Right kidney weight0.62.74.7-2.22.1-2.01.71.71.6-1.5-1.51.62.01.81.61.6-1.61.6-1.51.71.5-1.6-1.21.1-1.1
Cocaine induced anxiety0.10.20.7-0.80.8-0.70.10.40.1-0.1-0.10.10.40.60.50.3-0.40.3-0.50.70.3-0.2-0.0-0.00.0
Post-drug Anxiety0.80.91.9-1.41.3-1.20.70.90.7-0.7-0.70.60.91.11.30.8-0.90.9-1.21.20.8-0.3-0.50.5-0.5
Baseline Anxiety0.30.30.7-0.50.5-0.50.50.40.5-0.5-0.50.60.40.50.80.5-0.50.5-0.70.50.5-0.6-0.50.5-0.5
Tail length3.614.216.33.7-3.73.7-4.0-4.0-4.04.04.0-4.0-3.8-3.6-3.5-3.83.8-3.83.7-3.5-3.73.53.6-3.63.6
Length with tail4.218.520.33.9-4.04.1-4.5-4.4-4.54.54.5-4.5-4.1-4.2-4.1-4.44.4-4.44.3-4.1-4.44.14.4-4.44.4
Length without tail0.82.73.31.6-1.61.6-1.7-1.8-1.71.81.8-1.7-1.5-1.6-1.5-1.71.6-1.61.6-1.6-1.61.51.5-1.51.5
Times rat made contact with spout1.01.11.51.1-1.11.1-1.2-1.0-1.21.21.2-1.2-1.0-1.0-1.1-1.01.0-1.01.0-1.0-1.01.20.8-0.80.8
Lifetime Intake0.60.81.1-1.00.9-0.91.01.01.0-0.9-0.91.01.00.81.00.9-0.80.8-0.70.80.8-1.0-0.70.7-0.7
Liver weight, left2.84.65.91.7-1.91.9-2.0-2.0-2.02.12.1-2.1-1.8-2.2-2.2-2.12.2-2.32.3-2.4-2.32.22.4-2.42.4
Liver weight, right0.20.30.7-0.60.6-0.60.70.50.6-0.6-0.60.60.80.50.30.6-0.50.5-0.30.40.5-0.4-0.40.4-0.4
Locomotor activity0.00.00.10.2-0.10.1-0.3-0.0-0.30.20.2-0.3-0.20.10.10.0-0.10.1-0.10.30.2-0.1-0.30.3-0.3
Locomotor testing distance0.10.10.5-0.10.2-0.1-0.6-0.2-0.60.60.6-0.5-0.00.40.30.1-0.20.2-0.30.70.2-0.2-0.20.2-0.2
Locomotor testing rearing0.00.10.30.2-0.00.1-0.5-0.3-0.60.50.5-0.5-0.20.20.2-0.0-0.10.1-0.10.50.1-0.0-0.20.2-0.2
Locomotion in novel chamber1.21.52.3-0.80.8-0.91.51.41.5-1.5-1.51.41.41.00.81.3-1.21.2-0.90.61.2-0.8-1.41.5-1.5
Locomotion in novel chamber post-restriction0.00.10.30.1-0.10.00.20.30.2-0.2-0.20.10.3-0.0-0.10.3-0.20.3-0.0-0.10.30.3-0.50.5-0.5
Fecal boli incidents, locomotor time 11.11.52.01.4-1.41.4-1.3-1.3-1.31.31.3-1.3-1.3-1.3-1.3-1.21.2-1.21.3-1.1-1.21.41.0-1.01.0
Change in fecal boli incidents, locomotor task0.10.10.4-0.20.1-0.0-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.1-0.30.3-0.30.2-0.1-0.30.20.6-0.60.6
Time >=10cm from walls, locomotor time 12.52.73.31.4-1.41.5-1.6-1.6-1.61.61.6-1.6-1.6-1.6-1.6-1.71.7-1.71.6-1.7-1.71.81.8-1.81.8
Bouts of movement, locomotor time 12.12.45.01.1-1.21.3-1.5-1.4-1.51.41.4-1.6-1.4-1.5-1.4-1.61.6-1.61.5-1.5-1.62.21.8-1.81.8
Total resting periods, locomotor time 11.61.84.00.8-0.91.0-1.3-1.2-1.21.21.2-1.3-1.2-1.2-1.2-1.41.3-1.41.3-1.2-1.42.01.7-1.71.7
Rest time, locomotor task time 12.63.34.41.5-1.61.6-1.8-1.7-1.81.71.7-1.8-1.7-1.8-1.8-1.91.9-1.91.9-1.8-1.91.72.1-2.12.1
Distance moved, locomotor task time 10.71.01.7-0.70.7-0.81.01.01.0-1.0-1.01.01.00.80.91.1-1.11.1-1.00.71.1-1.2-1.31.3-1.3
Vertical activity count, locomotor time 10.71.62.6-0.80.9-1.01.21.21.2-1.2-1.21.21.21.21.21.3-1.31.4-1.31.11.4-1.5-1.61.6-1.6
Time >=10cm from walls, locomotor time 20.71.01.40.8-0.80.9-1.0-1.0-1.01.01.0-1.0-1.0-0.9-0.9-1.11.0-1.11.0-0.9-1.11.21.2-1.21.2
Bouts of movement, locomotor time 20.40.60.8-0.60.7-0.70.70.70.7-0.7-0.70.70.70.80.80.8-0.80.8-0.80.80.8-0.4-0.90.9-0.9
Total resting periods, locomotor time 20.10.10.2-0.10.2-0.20.20.20.2-0.2-0.20.20.20.30.30.3-0.40.4-0.30.30.40.1-0.50.5-0.5
Rest time, locomotor task time 21.92.44.01.0-1.11.2-1.5-1.5-1.51.51.5-1.5-1.5-1.4-1.4-1.71.6-1.71.5-1.4-1.71.12.0-2.02.0
Distance moved, locomotor task time 21.11.31.6-0.91.0-1.01.21.21.2-1.2-1.21.21.21.01.11.2-1.21.2-1.10.91.2-1.1-1.31.3-1.3
Vertical activity count, locomotor time 23.75.15.6-2.02.1-2.12.32.32.3-2.3-2.32.32.32.22.22.3-2.32.3-2.32.12.3-2.2-2.42.4-2.4
Light reinforcement 11.23.16.1-1.71.7-1.81.81.91.7-1.7-1.71.71.81.81.51.8-1.71.7-1.61.71.7-2.5-1.71.6-1.6
Light reinforcement 20.60.81.11.0-0.91.0-1.0-1.0-1.11.01.0-1.0-1.0-0.9-0.7-1.00.9-0.90.8-0.9-0.90.20.9-0.90.9
Bone: marrow area1.43.04.12.0-2.01.9-1.8-1.8-1.91.81.8-1.8-1.8-1.8-1.5-1.71.7-1.71.6-1.8-1.61.41.4-1.41.4
Bone: maximum diameter0.81.62.11.5-1.41.4-1.3-1.3-1.31.41.4-1.3-1.3-1.3-1.2-1.31.3-1.21.2-1.2-1.20.71.1-1.01.0
Bone: maximum force0.91.73.21.8-1.71.6-1.4-1.4-1.41.31.3-1.4-1.4-1.3-1.3-1.21.2-1.11.3-1.1-1.11.40.7-0.70.7
Bone: maximum moment0.50.81.81.3-1.21.2-1.0-1.1-1.01.01.0-1.0-1.1-0.8-0.8-0.90.8-0.80.9-0.7-0.70.90.4-0.40.4
Mean time between licks in bursts0.40.91.3-1.11.1-1.11.01.00.9-0.9-0.90.91.01.00.90.9-0.90.9-0.91.00.9-1.0-0.70.7-0.7
Mean num. licks in bursts0.40.71.10.6-0.60.6-0.9-0.9-1.01.01.0-1.0-0.6-0.8-0.6-0.80.8-0.80.8-0.9-0.80.80.9-0.90.9
Cd content in liver0.91.02.1-0.40.6-0.60.40.50.4-0.4-0.40.50.51.11.40.9-1.01.1-1.31.31.2-1.4-1.41.4-1.4
Co content in liver0.00.10.30.1-0.00.1-0.3-0.3-0.30.30.3-0.2-0.50.10.4-0.20.0-0.0-0.30.2-0.0-0.50.1-0.10.1
Cu content in liver0.20.31.10.10.0-0.10.30.40.3-0.3-0.30.30.30.40.60.5-0.60.6-0.60.30.7-0.4-1.01.0-1.0
Fe content in liver0.30.40.80.9-0.70.7-0.8-0.8-0.80.80.8-0.7-0.9-0.4-0.0-0.60.4-0.40.1-0.3-0.40.20.2-0.10.1
K content in liver0.30.30.7-0.80.6-0.60.80.80.8-0.8-0.80.70.70.20.10.4-0.30.2-0.1-0.10.20.20.0-0.00.1
Mg content in liver0.30.30.9-1.00.8-0.80.70.70.7-0.7-0.70.70.80.50.60.5-0.40.3-0.50.20.3-0.1-0.10.0-0.0
Mn content in liver1.21.42.2-1.51.4-1.41.21.21.2-1.2-1.21.21.31.31.21.2-1.21.1-1.21.21.1-0.8-0.90.9-0.8
Na content in liver0.40.52.20.5-0.70.6-0.2-0.2-0.20.20.2-0.4-0.1-0.8-0.9-0.40.6-0.70.9-1.3-0.71.50.6-0.50.6
Rb content in liver0.20.30.3-0.40.5-0.50.50.50.5-0.5-0.50.50.50.50.50.5-0.50.5-0.50.40.5-0.5-0.50.5-0.5
Se content in liver0.20.20.8-0.50.5-0.50.30.30.3-0.3-0.30.40.10.60.90.3-0.40.4-0.70.60.4-0.4-0.30.3-0.3
Sr content in liver1.11.01.70.6-0.70.8-0.9-0.9-0.90.90.9-0.9-0.9-1.0-1.0-1.01.0-1.11.0-1.0-1.11.01.3-1.31.3
Zn content in liver0.30.30.5-0.50.5-0.50.60.70.7-0.7-0.70.60.60.50.60.6-0.60.6-0.60.40.6-0.3-0.60.6-0.6
Bone: minimum diameter1.42.64.32.1-2.01.9-1.8-1.8-1.81.81.8-1.7-1.8-1.7-1.3-1.61.6-1.51.5-1.6-1.51.21.1-1.11.1
Time in familiar zone, hab. session 12.32.22.8-1.61.6-1.61.61.51.6-1.6-1.61.61.41.51.61.4-1.41.4-1.51.51.4-1.7-1.21.1-1.1
Time in novel zone, hab. session 16.96.97.52.6-2.62.6-2.7-2.7-2.72.72.7-2.7-2.6-2.6-2.7-2.62.6-2.62.7-2.5-2.62.62.5-2.52.4
Total zone transitions, hab. session 10.70.92.30.4-0.60.7-0.7-0.7-0.70.60.6-0.7-1.0-1.0-1.0-1.01.1-1.11.1-0.9-1.20.81.5-1.51.5
Total locomotion distance, hab. session 11.92.73.61.4-1.51.5-1.4-1.4-1.41.31.3-1.4-1.7-1.7-1.9-1.71.7-1.81.8-1.6-1.81.41.9-1.91.9
Locomotion velocity, hab. session 11.52.12.81.3-1.41.4-1.2-1.2-1.21.21.2-1.2-1.5-1.5-1.7-1.51.5-1.61.6-1.5-1.61.21.6-1.61.6
Time in familiar zone, hab. session 20.40.40.9-0.30.3-0.40.80.70.8-0.8-0.80.70.70.50.30.7-0.70.7-0.50.30.7-0.1-0.91.0-1.0
Time in novel zone, hab. session 20.20.20.7-0.00.00.1-0.6-0.5-0.60.60.6-0.5-0.5-0.2-0.0-0.50.4-0.50.30.0-0.5-0.20.8-0.80.8
Total zone transitions, hab. session 20.10.10.6-0.20.1-0.0-0.10.0-0.0-0.0-0.00.0-0.5-0.2-0.4-0.40.3-0.40.3-0.0-0.4-0.10.7-0.80.8
Total locomotion distance, hab. session 20.10.10.30.1-0.10.2-0.1-0.1-0.10.10.1-0.1-0.5-0.3-0.5-0.30.3-0.30.3-0.1-0.3-0.20.4-0.50.5
Locomotion velocity, hab. session 20.10.10.20.1-0.10.2-0.1-0.1-0.10.10.1-0.0-0.5-0.3-0.5-0.30.3-0.30.3-0.1-0.3-0.20.4-0.40.4
Novel to familiar place preference ratio1.61.72.80.8-0.91.0-1.2-1.1-1.21.21.2-1.2-1.2-1.3-1.4-1.31.4-1.41.4-1.2-1.41.11.6-1.71.7
Novelty place preference1.82.03.20.9-1.11.1-1.3-1.2-1.31.31.3-1.3-1.2-1.4-1.5-1.41.5-1.51.6-1.4-1.61.41.8-1.81.8
Time in novel zone, NPP test2.12.33.41.1-1.21.2-1.4-1.3-1.41.41.4-1.4-1.3-1.5-1.6-1.51.6-1.61.7-1.5-1.61.41.8-1.81.9
Total zone transitions, NPP test0.20.30.70.1-0.30.3-0.2-0.0-0.10.00.0-0.1-0.6-0.6-0.6-0.50.6-0.60.6-0.6-0.60.70.8-0.80.8
Total locomotion distance, NPP test0.50.61.20.5-0.60.7-0.5-0.3-0.50.40.4-0.5-1.0-0.9-0.9-0.80.9-0.90.8-0.9-0.90.81.1-1.11.1
Locomotion velocity, NPP test0.20.20.60.2-0.30.3-0.2-0.0-0.10.10.1-0.2-0.6-0.6-0.6-0.50.5-0.60.5-0.6-0.60.50.8-0.80.8
Intraocular pressure3.24.68.6-2.32.3-2.22.02.12.0-1.9-1.92.12.02.32.32.0-2.12.1-2.22.32.1-2.9-1.91.8-1.8
Delta distance traveled before/after self-admin2.32.43.9-1.11.2-1.31.61.61.6-1.6-1.61.51.41.41.41.7-1.71.7-1.51.51.7-0.9-1.92.0-2.0
Delta ambulatory time before/after self-admin2.22.74.0-1.21.3-1.41.61.71.6-1.6-1.61.61.51.51.61.7-1.71.8-1.61.61.8-1.0-2.02.0-2.0
Parametrial fat weight0.00.10.2-0.10.2-0.1-0.3-0.4-0.40.40.4-0.3-0.20.30.3-0.20.0-0.0-0.10.5-0.0-0.20.2-0.20.2
Pavlov. Cond. lever latency0.10.20.5-0.30.4-0.40.30.40.3-0.3-0.30.40.20.40.40.4-0.40.4-0.50.50.4-0.7-0.40.4-0.4
Pavlov. Cond. magazine entry latency1.01.22.31.5-1.41.3-1.2-1.2-1.21.21.2-1.2-1.1-1.1-1.1-1.01.0-0.91.0-1.1-0.91.20.6-0.60.5
Pavlov. Cond. change in total contacts0.00.00.1-0.10.1-0.10.10.10.1-0.1-0.10.10.30.10.10.2-0.20.2-0.10.00.20.3-0.20.2-0.2
Pavlov. Cond. index score0.50.71.40.9-0.90.9-0.8-0.8-0.80.80.8-0.8-0.6-0.9-0.9-0.70.8-0.80.9-1.0-0.81.20.6-0.60.6
Pavlov. Cond. latency score0.50.61.30.8-0.90.8-0.7-0.8-0.70.70.7-0.8-0.6-0.8-0.8-0.70.7-0.70.8-0.9-0.71.10.6-0.60.6
Pavlov. Cond. lever contacts0.10.10.70.2-0.30.3-0.2-0.2-0.20.10.1-0.2-0.1-0.4-0.4-0.30.3-0.40.4-0.6-0.40.80.3-0.30.3
Pavlov. Cond. magazine entry number0.20.30.5-0.70.7-0.60.60.70.6-0.6-0.60.60.50.50.50.5-0.50.5-0.50.50.4-0.6-0.30.3-0.3
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.30.2-0.10.10.00.1-0.1-0.10.1-0.10.00.1-0.10.1-0.20.1-0.0-0.2-0.20.4-0.40.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.41.0-1.00.9-0.7-0.8-0.70.70.7-0.8-0.7-0.9-0.9-0.70.8-0.70.8-1.0-0.71.20.5-0.50.5
Pavlov. Cond. response bias0.60.81.10.9-0.90.9-0.9-1.0-0.90.90.9-0.9-0.8-0.9-1.0-0.90.9-0.90.9-0.9-0.81.10.7-0.70.7
Pavlov. Cond. lever latency1.41.92.2-1.51.5-1.51.41.41.4-1.4-1.41.41.51.41.31.4-1.41.4-1.31.31.4-1.2-1.31.3-1.3
Pavlov. Cond. magazine entry latency0.20.30.70.8-0.80.7-0.5-0.6-0.50.50.5-0.5-0.5-0.5-0.6-0.40.4-0.40.5-0.6-0.40.60.2-0.10.1
Pavlov. Cond. change in total contacts1.42.32.61.4-1.41.5-1.5-1.6-1.51.51.5-1.5-1.6-1.5-1.4-1.61.6-1.61.5-1.5-1.61.21.6-1.61.6
Pavlov. Cond. index score1.82.42.91.7-1.71.7-1.5-1.6-1.51.51.5-1.5-1.6-1.6-1.6-1.61.6-1.61.6-1.6-1.51.51.4-1.41.4
Pavlov. Cond. latency score1.62.12.61.6-1.61.6-1.4-1.5-1.41.41.4-1.4-1.5-1.5-1.5-1.41.5-1.41.4-1.5-1.41.51.3-1.21.2
Pavlov. Cond. lever contacts2.23.03.41.8-1.81.8-1.7-1.7-1.71.71.7-1.7-1.8-1.8-1.7-1.81.8-1.81.7-1.7-1.81.41.7-1.71.7
Pavlov. Cond. magazine entry number0.60.81.5-1.21.2-1.10.80.90.8-0.8-0.80.80.71.01.10.8-0.80.8-0.91.10.7-1.2-0.50.4-0.4
Pavlov. Cond. intertrial magazine entries1.62.34.0-2.01.9-1.91.51.61.4-1.4-1.41.41.71.71.71.5-1.51.4-1.51.61.4-1.5-1.11.0-1.0
Pavlov. Cond. lever-magazine prob. diff.1.62.12.51.6-1.61.6-1.4-1.5-1.41.41.4-1.4-1.5-1.5-1.5-1.51.5-1.51.5-1.5-1.51.41.3-1.31.3
Pavlov. Cond. response bias2.23.03.41.8-1.81.8-1.7-1.7-1.71.71.7-1.7-1.8-1.8-1.8-1.81.8-1.81.7-1.7-1.71.51.6-1.61.6
Time in closed arm before self-admin1.51.94.22.1-1.91.7-1.7-1.6-1.71.71.7-1.6-1.4-1.3-1.2-1.21.1-1.01.2-1.3-1.01.00.5-0.40.4
Time in closed arm after self-admin0.00.10.20.5-0.30.3-0.2-0.2-0.20.20.2-0.2-0.3-0.1-0.0-0.10.00.0-0.00.10.10.2-0.30.3-0.3
Time in open arm before self-admin2.42.64.8-2.22.1-2.01.81.71.8-1.8-1.81.71.81.61.71.5-1.51.4-1.61.61.4-1.2-1.00.9-0.9
Time in open arm after self-admin2.12.43.31.4-1.51.5-1.4-1.4-1.41.41.4-1.4-1.3-1.7-1.7-1.51.6-1.61.7-1.8-1.61.71.6-1.61.6
Bone: periosteal estimation1.53.24.92.2-2.12.1-1.9-1.9-1.91.91.9-1.9-1.9-1.9-1.6-1.71.7-1.71.7-1.8-1.61.41.3-1.31.3
Bone: periosteal perimeter1.11.82.71.7-1.61.6-1.5-1.5-1.51.51.5-1.4-1.5-1.3-1.2-1.31.3-1.31.2-1.3-1.30.91.0-1.01.0
Bone: post-yield work0.10.10.30.3-0.10.1-0.0-0.1-0.00.00.00.1-0.10.20.30.1-0.20.3-0.30.30.3-0.5-0.50.5-0.6
Progressive ratio test 1 active lever presses0.10.10.3-0.20.2-0.30.40.40.4-0.4-0.40.40.50.20.50.4-0.40.4-0.10.10.4-0.4-0.50.5-0.5
Progressive ratio test 1 breakpoint0.10.10.2-0.10.1-0.20.40.40.4-0.4-0.40.40.40.10.30.4-0.30.30.1-0.00.3-0.2-0.40.4-0.4
Progressive ratio test 1 inactive lever presses1.42.03.4-1.21.3-1.31.41.31.3-1.3-1.31.41.31.41.81.4-1.41.4-1.31.31.4-1.7-1.41.4-1.4
Progressive ratio test 2 active lever presses0.00.10.2-0.20.1-0.20.30.50.3-0.2-0.20.20.4-0.00.20.3-0.10.10.3-0.10.1-0.1-0.10.1-0.1
Progressive ratio test 2 breakpoint0.00.00.2-0.10.0-0.10.10.30.1-0.1-0.10.10.2-0.10.00.10.0-0.00.5-0.2-0.10.10.1-0.00.1
Progressive ratio test 2 inactive lever presses0.50.71.4-0.70.6-0.71.01.21.0-1.0-1.00.91.20.40.91.0-0.80.8-0.50.20.80.0-0.91.0-0.9
Incentive Sensitization - Responses0.10.10.5-0.0-0.10.1-0.00.2-0.00.10.1-0.10.1-0.4-0.3-0.10.3-0.30.7-0.6-0.40.60.4-0.40.5
Incentive Sensitization - Breakpoint0.10.10.4-0.1-0.10.0-0.00.2-0.00.00.0-0.10.1-0.3-0.3-0.10.2-0.30.6-0.5-0.30.50.4-0.40.4
Sum of active levers in priming session hrs 5-61.31.22.81.7-1.71.5-0.9-0.9-0.80.80.8-0.9-1.0-1.4-1.4-0.91.0-1.01.3-1.5-0.91.40.5-0.40.4
Progressive ratio0.10.10.5-0.0-0.00.1-0.3-0.3-0.30.30.3-0.3-0.3-0.2-0.3-0.40.4-0.40.3-0.2-0.4-0.20.7-0.70.7
Food seeking constrained by brief footshock2.32.84.1-1.21.3-1.42.01.72.0-2.0-2.01.91.71.41.31.8-1.71.7-1.51.31.7-1.3-1.91.9-1.9
Seeking ratio, punishment vs. effort1.01.53.3-0.50.6-0.81.31.21.3-1.3-1.31.21.20.90.91.4-1.31.3-1.00.81.4-0.5-1.71.8-1.8
Retroperitoneal fat weight0.72.83.9-1.61.7-1.71.51.31.4-1.3-1.31.51.71.91.91.7-1.81.8-1.82.01.8-1.9-1.71.7-1.7
Reaction time number correct0.30.61.1-0.80.9-0.80.90.60.9-1.1-1.10.90.60.80.90.6-0.70.7-0.81.00.7-0.8-0.50.5-0.5
Reaction time mean minus median0.00.00.2-0.20.1-0.1-0.10.1-0.10.30.3-0.20.3-0.1-0.20.00.1-0.10.3-0.3-0.10.40.2-0.20.3
Reaction time mean minus median AUC0.10.30.70.1-0.20.2-0.3-0.3-0.40.50.5-0.4-0.1-0.5-0.7-0.40.5-0.60.7-0.6-0.60.80.7-0.80.8
Reaction time num false alarms3.85.36.1-2.32.3-2.32.22.52.2-2.3-2.32.22.32.42.32.4-2.42.4-2.42.42.4-2.0-2.32.3-2.3
Reaction time num false alarms AUC2.94.65.6-2.42.3-2.32.12.32.1-2.1-2.12.02.12.32.12.2-2.22.2-2.22.32.1-1.7-1.91.9-1.9
Reaction time trials correct on left0.30.61.1-0.80.9-0.80.90.60.9-1.1-1.10.90.60.80.90.6-0.70.7-0.81.00.7-0.8-0.50.5-0.5
Reaction time trials on left0.30.61.1-0.90.9-0.80.90.60.9-1.0-1.00.90.60.80.90.6-0.70.7-0.81.00.7-0.8-0.50.5-0.5
Reaction time mean3.45.46.92.3-2.32.3-2.5-2.3-2.52.62.6-2.5-2.1-2.3-2.3-2.22.3-2.32.3-2.4-2.32.12.1-2.12.1
Reaction time mean AUC2.64.15.62.0-2.02.0-2.2-2.0-2.22.42.4-2.2-1.8-2.0-2.0-2.02.0-2.02.0-2.1-2.01.81.8-1.81.8
Median of all reaction times5.47.79.42.9-2.92.9-3.0-2.8-3.03.13.1-3.0-2.7-2.8-2.7-2.72.7-2.72.8-2.8-2.72.42.5-2.42.4
Reaction time omissions0.10.10.5-0.50.5-0.4-0.10.1-0.10.10.1-0.00.10.50.70.1-0.20.2-0.50.60.2-0.40.0-0.10.1
Reaction time false alarm rate1.52.02.5-1.51.5-1.51.21.61.2-1.3-1.31.21.41.61.41.5-1.51.5-1.51.51.5-1.1-1.41.4-1.4
Reaction time premature initiation rate0.20.30.30.4-0.40.5-0.5-0.3-0.50.50.5-0.5-0.5-0.6-0.5-0.50.5-0.50.5-0.5-0.50.20.6-0.60.6
Reaction time premature initiations0.00.00.1-0.20.1-0.10.00.10.0-0.1-0.10.1-0.1-0.00.1-0.10.1-0.10.00.1-0.1-0.20.3-0.30.3
Std. dev. reaction times0.61.11.90.9-0.90.9-1.2-1.0-1.21.41.4-1.2-0.7-0.9-1.0-0.91.0-1.01.1-1.1-1.01.20.9-0.90.9
Reaction time trials completed0.30.61.1-0.90.9-0.80.90.60.9-1.0-1.00.90.60.80.90.6-0.70.7-0.81.00.7-0.8-0.50.5-0.5
Reaction time trials AUC0.20.40.8-0.70.7-0.70.80.50.8-0.9-0.90.80.50.60.70.5-0.50.5-0.60.80.5-0.7-0.30.3-0.3
Run reversals in cocaine runway, females0.30.31.0-0.80.8-0.70.40.40.4-0.4-0.40.40.40.61.00.4-0.50.5-0.70.80.4-0.3-0.20.2-0.2
Run reversals in cocaine runway, males0.30.30.60.7-0.60.7-0.6-0.8-0.60.60.6-0.6-0.8-0.5-0.5-0.60.6-0.50.5-0.3-0.50.50.4-0.40.4
Latency to leave start box in cocaine runway2.73.03.6-1.91.9-1.91.71.81.7-1.7-1.71.71.81.81.71.8-1.81.7-1.81.71.7-1.7-1.61.6-1.5
Latency to leave start box in cocaine runway, F2.22.63.1-1.71.7-1.71.51.51.5-1.5-1.51.51.51.71.61.6-1.61.6-1.71.81.6-1.7-1.51.4-1.4
Latency to leave start box in cocaine runway, M0.80.71.1-1.01.0-1.01.01.01.0-0.9-0.90.91.00.80.70.9-0.80.8-0.70.60.8-0.7-0.70.7-0.6
Std. dev. time between licks in bursts2.83.75.3-2.32.2-2.12.12.32.2-2.2-2.22.12.02.01.71.9-1.81.8-1.82.01.7-1.6-1.41.4-1.4
Total sessions with >9 infusions0.00.00.2-0.30.3-0.20.00.10.00.00.00.10.10.10.40.0-0.00.0-0.10.10.0-0.40.1-0.20.2
Short access day 1 total inactive lever presses0.71.01.9-1.11.0-1.01.11.11.1-1.2-1.21.01.10.71.41.0-0.90.9-0.90.70.9-0.2-0.80.8-0.8
Short access day 10 total inactive lever presses0.10.30.70.8-0.70.7-0.8-0.8-0.80.80.8-0.8-0.8-0.4-0.2-0.50.4-0.30.1-0.1-0.30.60.1-0.10.1
Short access day 1 total infusions0.20.31.1-0.60.7-0.60.40.40.4-0.4-0.40.50.40.61.00.4-0.40.4-0.60.60.4-1.0-0.30.2-0.2
Short access day 10 total infusions0.20.30.5-0.70.6-0.60.50.70.5-0.5-0.50.50.70.40.50.5-0.50.5-0.30.40.4-0.5-0.40.3-0.3
Short access total infusions0.81.01.9-1.21.2-1.10.90.90.9-0.9-0.91.00.91.11.30.9-0.90.9-1.01.20.9-1.4-0.70.7-0.7
Short access day 1 locomotion0.40.50.90.7-0.70.7-0.9-0.7-0.90.90.9-0.9-0.7-0.7-0.5-0.60.6-0.60.6-0.6-0.60.40.5-0.50.5
Short access day 10 total locomotion0.30.51.1-0.50.5-0.60.40.70.4-0.4-0.40.40.70.80.90.8-0.80.9-0.80.70.9-0.2-1.01.0-1.1
Short access total locomotion0.91.11.5-1.11.1-1.10.81.20.8-0.7-0.70.71.21.11.21.2-1.21.1-1.01.01.1-0.6-1.11.1-1.1
One hour access (0.3 mA shock)0.30.30.6-0.30.2-0.40.70.80.8-0.8-0.80.60.70.30.30.6-0.50.5-0.10.10.50.1-0.70.7-0.7
Compulsive drug intake0.10.10.4-0.20.3-0.20.3-0.00.4-0.4-0.40.3-0.00.4-0.00.1-0.20.2-0.50.60.30.1-0.20.2-0.2
One hour access (shock baseline)0.10.20.6-0.40.4-0.40.30.60.3-0.3-0.30.30.60.40.80.5-0.40.4-0.20.30.4-0.7-0.50.5-0.5
Social response proportion0.30.40.50.5-0.50.6-0.5-0.6-0.50.50.5-0.5-0.5-0.6-0.6-0.60.7-0.70.7-0.6-0.70.50.7-0.70.7
Social responses0.60.71.20.9-0.90.9-0.8-0.8-0.80.80.8-0.9-0.7-0.9-1.1-0.80.8-0.81.0-1.0-0.80.90.7-0.70.7
Social time0.30.40.60.5-0.60.6-0.6-0.5-0.50.50.5-0.6-0.5-0.7-0.6-0.60.6-0.60.7-0.7-0.60.70.6-0.60.6
Soleus weight0.10.20.9-0.90.7-0.70.70.60.7-0.7-0.70.60.80.20.00.4-0.20.2-0.10.00.10.10.2-0.20.3
Bone: stiffness0.81.22.11.4-1.41.3-1.1-1.2-1.11.11.1-1.2-1.1-1.1-1.2-1.01.1-1.01.2-1.0-1.01.20.8-0.70.7
Tibialis anterior weight0.41.52.3-1.51.4-1.41.41.41.4-1.3-1.31.31.51.11.11.3-1.21.1-1.01.01.1-0.9-0.90.9-0.9
Time to tail flick, vehicle, before self-admin0.10.10.20.4-0.40.4-0.1-0.2-0.10.00.0-0.1-0.3-0.3-0.4-0.20.3-0.30.4-0.5-0.30.10.2-0.20.2
Time to tail flick, vehicle, after self-admin0.81.02.21.0-0.91.0-1.2-1.1-1.21.11.1-1.2-1.2-0.9-0.7-1.00.9-0.90.7-0.5-0.91.50.8-0.80.8
Time to tail flick, test, before self-admin0.50.51.10.3-0.30.4-0.8-1.0-0.80.80.8-0.8-0.8-0.4-0.2-0.90.7-0.70.3-0.2-0.70.61.0-1.01.0
Time to tail flick, test, after self-admin3.23.34.5-1.91.8-1.82.12.02.1-2.1-2.12.01.91.71.71.9-1.81.7-1.61.51.7-1.1-1.61.6-1.6
Delta time to tail flick, vehicle, before/after SA0.00.00.2-0.00.1-0.1-0.2-0.1-0.20.20.2-0.2-0.20.10.2-0.0-0.10.1-0.30.40.10.4-0.10.0-0.0
Delta time to tail flick, test, before/after SA2.93.04.4-1.51.4-1.62.02.12.0-2.0-2.02.01.91.41.31.9-1.71.7-1.31.11.7-1.3-1.81.8-1.8
Tibia length1.54.25.12.2-2.22.2-2.2-2.2-2.22.22.2-2.2-2.1-2.1-2.0-2.02.0-2.02.0-2.0-2.01.91.8-1.81.8
Ambulatory time before self-admin1.31.93.41.5-1.61.5-1.1-1.2-1.11.11.1-1.1-1.1-1.6-1.7-1.31.4-1.41.7-1.8-1.41.31.3-1.21.2
Ambulatory time after self-admin0.91.02.8-0.10.2-0.41.21.01.2-1.2-1.21.11.00.50.51.1-1.01.1-0.70.41.1-0.4-1.61.7-1.7
Bone: tissue strength0.50.51.5-0.30.5-0.50.40.30.4-0.4-0.40.50.30.81.00.6-0.70.7-0.91.00.8-1.2-0.90.9-0.9
Total heroin consumption0.70.91.61.2-1.21.1-0.9-1.0-0.90.80.8-0.9-1.0-1.0-1.1-0.90.9-0.80.9-0.9-0.81.10.6-0.60.5
Bone: trabecular number0.20.30.7-0.30.3-0.40.60.60.6-0.6-0.60.60.60.50.30.6-0.60.6-0.40.50.6-0.4-0.80.8-0.8
Bone: trabecular spacing0.60.71.30.7-0.70.8-1.1-1.0-1.11.11.1-1.0-0.9-0.7-0.4-0.90.8-0.80.6-0.6-0.80.50.9-0.90.9
Bone: trabecular thickness0.40.51.01.0-1.00.9-0.6-0.7-0.60.60.6-0.6-0.7-0.9-1.0-0.70.7-0.70.9-0.9-0.70.60.5-0.40.4
Bone: trabecular tissue density1.01.52.01.3-1.31.3-1.4-1.3-1.41.31.3-1.4-1.3-1.2-1.3-1.31.2-1.21.1-1.1-1.21.11.1-1.11.0
Water consumed over 24 hours0.00.00.10.1-0.10.00.10.10.10.10.10.00.2-0.0-0.20.1-0.10.10.10.00.10.2-0.20.2-0.2
Number of responses in last shaping day0.70.71.51.0-0.90.9-1.2-1.0-1.21.21.2-1.1-0.9-0.7-0.2-0.80.7-0.70.6-0.7-0.70.40.6-0.50.5