Hub : Genes

Plekha7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_063279498.1 0.03 0.03 6.3e-03 0.01 0.01 0.01 0.01 1.6e-02 2.0e-02 2.3e-02 2.6e-02
2 OFC gene expression Plekha7 0.38 0.23 1.4e-05 0.11 0.12 0.13 0.12 1.3e-03 7.9e-04 6.1e-04 8.4e-04
3 NAcc gene expression Plekha7 0.03 0.04 8.2e-05 0.02 0.03 0.03 0.03 1.6e-04 5.8e-05 6.9e-05 8.7e-05
4 Brain alternative TSS XM_039101147.2 0.03 0.03 3.2e-03 0.01 0.02 0.01 0.01 2.1e-02 7.5e-03 1.4e-02 1.6e-02
5 pVTA isoform ratio XM_063279492.1 0.04 0.04 2.4e-03 0.02 0.02 0.01 0.01 1.5e-02 1.1e-02 1.9e-02 1.9e-02
6 BLA isoform ratio XM_039101147.2 0.07 0.07 1.7e-03 0.03 0.04 0.04 0.03 1.5e-02 2.9e-03 4.3e-03 9.8e-03
7 pVTA intron excision ratio chr1_179833716_179836198 0.05 0.05 6.8e-04 0.01 0.02 0 0.01 2.5e-02 4.5e-03 1.6e-01 6.0e-02
8 IC gene expression Plekha7 0.08 0.07 8.2e-03 0.02 0.02 0.01 0.02 5.9e-02 4.0e-02 7.7e-02 6.1e-02
9 pVTA intron excision ratio chr1_179800164_179803798 0.05 0.05 6.2e-04 0.03 0.04 0.03 0.02 4.1e-03 6.2e-04 4.2e-03 5.7e-03
10 BLA alternative polyA XM_063279483.1 0.09 0.09 2.0e-04 0.06 0.06 0.04 0.04 6.4e-04 6.2e-04 6.1e-03 2.3e-03
11 pVTA gene expression Plekha7 0.17 0.11 1.3e-15 0.18 0.18 0.18 0.18 1.9e-14 1.2e-14 3.0e-14 3.0e-14
12 Brain alternative TSS XM_063279498.1 0.03 0.03 9.0e-03 0.01 0.01 0.01 0.01 3.5e-02 5.5e-02 7.4e-02 8.7e-02
13 BLA gene expression Plekha7 0.12 0.11 1.6e-05 0.07 0.08 0.07 0.07 1.8e-04 3.9e-05 1.5e-04 2.1e-04
14 PL gene expression Plekha7 0.03 0.04 1.6e-03 0.02 0.02 0.02 0.02 1.8e-03 1.2e-03 1.7e-03 6.8e-03
15 Eye isoform ratio XM_039101152.2 0.43 0.26 6.2e-03 0.03 0.05 0 0.03 1.0e-01 6.9e-02 3.0e-01 1.3e-01
16 BLA alternative TSS XM_063279498.1 0.06 0.07 9.8e-03 0.01 0.01 0 0 5.0e-02 1.5e-01 2.2e-01 2.9e-01
17 Brain gene expression Plekha7 0.18 0.12 9.5e-13 0.15 0.13 0.13 0.13 1.2e-13 7.1e-12 5.0e-12 5.4e-12
18 Adipose gene expression Plekha7 0.34 0.18 3.1e-06 0.02 0.06 0.03 0.02 9.2e-04 8.0e-07 1.3e-04 1.6e-03
19 NAcc alternative TSS XM_039101147.2 0.01 0.01 1.0e-02 0.01 0.01 0.01 0.01 3.4e-03 1.7e-02 3.2e-03 5.9e-03
20 BLA alternative polyA XM_063279498.1 0.06 0.06 1.8e-03 0.04 0.03 0.01 0.02 6.0e-03 1.0e-02 8.9e-02 3.3e-02
21 BLA alternative polyA XM_063279498.1 0.05 0.05 4.7e-03 0.03 0.02 -0 0.01 1.7e-02 3.0e-02 3.7e-01 1.1e-01
22 NAcc alternative TSS XM_063279498.1 0.02 0.02 3.6e-03 0.02 0.01 0.01 0.02 8.3e-04 2.5e-03 4.7e-03 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.81.31.7-1.1-1.3-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.11.1-1.1-1.21.11.31.21.2-1.2
Area under the delay curve0.50.61.30.50.70.7-0.70.7-0.70.70.70.80.70.80.60.70.8-0.80.60.7-0.4-1.1-1.0-1.01.1
BMI with tail10.435.839.1-6.0-6.2-6.16.0-6.06.0-6.0-6.1-6.0-6.0-6.0-5.9-6.0-6.06.0-5.8-6.05.76.35.95.9-5.4
BMI without tail8.425.528.0-5.3-5.0-5.15.1-5.15.2-5.1-5.1-5.1-5.1-5.0-5.2-5.1-5.05.0-5.1-4.95.35.14.94.9-4.4
Body weight6.528.331.7-5.4-5.4-5.45.3-5.35.3-5.3-5.4-5.4-5.3-5.3-5.3-5.3-5.35.3-5.2-5.35.35.65.15.1-5.2
Weight adjusted by age0.61.01.3-0.9-0.9-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-0.9-1.0-1.01.0-0.9-1.11.01.00.80.8-1.1
Bone surface0.91.62.1-1.4-1.3-1.31.3-1.31.3-1.3-1.3-1.3-1.3-1.3-1.4-1.3-1.31.2-1.4-1.31.41.00.90.9-1.1
Bone volume1.11.92.1-1.4-1.5-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.41.41.31.11.1-1.3
Breakpoint value in progressive ratio session3.03.65.72.11.82.0-2.02.0-2.12.11.91.92.01.92.11.91.9-1.82.31.9-2.4-1.4-1.5-1.51.0
Number of licking bursts4.16.68.12.72.42.7-2.72.7-2.72.72.72.72.72.72.72.72.7-2.72.82.6-2.7-2.2-1.9-1.92.2
Context. condit. distance diff. score0.70.81.41.10.90.9-0.90.9-0.90.90.90.90.90.91.20.90.9-0.91.21.0-0.8-0.4-0.6-0.6-0.1
Locomotion velocity, session 13.23.43.91.62.01.9-1.91.9-1.91.91.91.91.91.91.71.91.9-1.91.71.9-1.6-1.9-1.9-1.91.4
Locomotion distance, session 10.10.10.70.30.30.2-0.20.2-0.20.20.20.20.20.20.40.20.2-0.20.40.20.1-0.2-0.8-0.8-0.8
Locomotion velocity, session 23.94.56.71.82.32.1-2.12.1-2.12.12.12.12.12.11.92.12.1-2.11.92.1-1.8-2.5-2.6-2.61.8
Locomotion distance, session 20.00.10.20.30.10.2-0.20.2-0.20.20.20.20.20.20.30.20.2-0.20.30.1-0.1-0.1-0.4-0.4-0.5
Locomotion velocity, session 30.00.00.4-0.00.00.0-0.00.0-0.00.0-0.0-0.00.0-0.00.0-0.0-0.00.00.0-0.0-0.1-0.4-0.6-0.6-0.2
Locomotion distance, session 30.10.10.40.10.10.1-0.10.1-0.10.10.10.10.10.10.10.10.1-0.00.1-0.0-0.3-0.6-0.5-0.50.6
Stereotopy head waving bouts, day 31.31.62.41.21.41.3-1.21.3-1.21.21.31.31.31.31.21.31.3-1.31.21.4-0.7-1.2-1.5-1.50.3
Stereotopy head waving duration, day 31.41.62.41.11.51.3-1.21.3-1.21.21.31.31.31.31.21.31.3-1.41.21.4-0.7-1.3-1.5-1.50.5
Locomotion velocity, session 70.10.11.40.00.40.3-0.30.3-0.20.20.30.30.30.30.10.30.4-0.40.10.4-0.2-0.5-0.0-0.01.2
Locomotion distance, session 70.91.12.90.91.11.1-1.11.1-1.11.11.11.11.11.10.91.11.1-1.10.91.1-1.0-1.1-0.6-0.61.7
Stereotopy head waving bouts, day 70.60.71.00.71.00.9-0.90.9-0.90.91.01.01.01.00.71.01.0-1.00.71.0-0.6-0.3-0.4-0.40.1
Stereotopy head waving duration, day 70.30.30.7-0.6-0.4-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.7-0.4-0.40.4-0.7-0.40.80.80.60.6-0.9
Locomotion velocity, session 82.02.43.11.41.51.5-1.61.5-1.61.61.51.51.51.51.51.51.5-1.51.51.4-1.7-1.7-1.8-1.81.2
Locomotion distance, session 80.91.32.01.31.11.2-1.21.2-1.21.21.21.21.21.21.41.21.2-1.21.41.1-1.0-0.7-0.9-0.90.0
Degree of sensitization distance0.40.40.70.50.80.7-0.60.7-0.60.60.70.70.70.70.50.70.7-0.80.50.8-0.2-0.3-0.3-0.30.3
Degree of sensitization stereotypy0.00.00.1-0.00.10.2-0.20.2-0.20.20.20.20.20.2-0.10.20.2-0.2-0.10.20.00.40.40.4-0.3
Conditioned locomotion0.40.51.10.70.70.7-0.70.7-0.80.80.70.70.70.70.70.70.7-0.60.60.7-1.1-0.6-0.5-0.50.5
Cocaine response after cond. corrected0.30.40.70.70.80.6-0.50.6-0.50.50.60.60.60.60.60.60.6-0.70.60.8-0.3-0.8-0.7-0.70.8
Cocaine response after cond. not corrected0.50.60.9-0.8-0.7-0.80.9-0.80.9-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.80.7-0.9-0.60.90.40.60.60.0
Cocaine response before conditioning5.46.47.2-2.7-2.7-2.62.6-2.62.6-2.6-2.6-2.6-2.6-2.6-2.7-2.6-2.62.6-2.7-2.62.22.22.42.4-1.4
Saline control response0.40.50.9-0.9-0.6-0.70.7-0.70.7-0.7-0.6-0.6-0.6-0.6-0.9-0.6-0.60.6-0.9-0.60.90.70.70.7-0.6
Bone: connectivity density1.32.12.9-1.5-1.5-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.5-1.4-1.41.3-1.5-1.41.51.61.71.7-0.9
Bone: cortical apparent density3.14.25.42.02.12.0-2.02.0-2.02.02.02.02.02.02.02.02.0-2.12.02.0-1.9-2.3-2.2-2.22.1
Bone: cortical area1.42.23.7-1.7-1.4-1.61.6-1.61.6-1.6-1.5-1.5-1.6-1.5-1.7-1.5-1.51.5-1.6-1.41.91.00.60.6-1.5
Bone: cortical porosity2.02.12.7-1.3-1.6-1.51.4-1.41.4-1.4-1.5-1.5-1.5-1.5-1.3-1.5-1.51.5-1.3-1.61.01.61.71.7-1.2
Bone: cortical porosity1.01.01.3-0.9-1.1-1.01.0-1.01.0-1.0-1.1-1.1-1.0-1.1-0.9-1.1-1.11.1-0.9-1.10.71.11.01.0-1.1
Bone: cortical thickness0.10.10.4-0.2-0.1-0.20.2-0.20.3-0.3-0.2-0.2-0.2-0.2-0.3-0.2-0.20.1-0.3-0.10.6-0.3-0.7-0.7-0.4
Bone: cortical thickness0.10.10.30.30.40.3-0.30.3-0.30.30.30.30.30.30.30.30.3-0.30.30.4-0.2-0.6-0.6-0.60.4
Bone: cortical tissue density3.04.15.32.02.12.0-2.02.0-2.02.02.02.02.02.02.02.02.0-2.02.02.0-1.9-2.3-2.1-2.12.0
Condit. Reinf. active minus inactive responses0.10.20.9-0.2-0.4-0.40.3-0.30.3-0.3-0.4-0.4-0.4-0.4-0.2-0.4-0.40.4-0.2-0.40.30.50.20.2-0.9
Condit. Reinf. active-inactive response ratio0.91.01.5-0.9-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-0.9-1.0-1.01.0-0.9-1.00.91.21.11.1-1.2
Condit. Reinf. active responses0.00.00.3-0.0-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.0-0.1-0.10.1-0.0-0.10.1-0.0-0.3-0.3-0.5
Condit. Reinf. inactive responses0.00.00.1-0.1-0.1-0.20.1-0.10.1-0.1-0.2-0.2-0.2-0.2-0.1-0.2-0.20.2-0.1-0.2-0.0-0.2-0.3-0.3-0.2
Incentive salience index mean0.20.30.4-0.4-0.7-0.60.5-0.60.5-0.5-0.6-0.6-0.6-0.6-0.4-0.6-0.60.7-0.4-0.70.10.30.30.3-0.3
Condit. Reinf. lever presses0.00.00.30.0-0.2-0.10.1-0.10.1-0.1-0.2-0.2-0.2-0.20.0-0.2-0.20.20.0-0.2-0.4-0.4-0.2-0.20.5
Condit. Reinf. active minus inactive responses1.51.95.6-1.1-1.4-1.41.3-1.41.3-1.3-1.4-1.4-1.3-1.4-1.1-1.3-1.41.4-1.1-1.31.41.71.01.0-2.4
Condit. Reinf. active-inactive response ratio0.91.02.2-0.8-1.0-1.01.0-1.01.0-1.0-0.9-0.9-0.9-0.9-0.8-0.9-0.90.9-0.9-0.81.11.31.01.0-1.5
Condit. Reinf. active responses1.31.84.8-1.0-1.5-1.41.3-1.41.3-1.3-1.4-1.4-1.4-1.4-1.0-1.4-1.41.5-1.1-1.51.21.50.90.9-2.2
Condit. Reinf. inactive responses0.71.01.5-0.8-1.1-1.11.0-1.11.0-1.0-1.1-1.1-1.1-1.1-0.9-1.1-1.11.1-0.9-1.20.70.70.60.6-0.7
Condit. Reinf. lever presses4.25.87.2-2.5-2.4-2.52.5-2.52.5-2.5-2.5-2.5-2.4-2.5-2.5-2.4-2.42.4-2.5-2.42.62.21.71.7-2.7
Condit. Reinf. lever reinforcers received1.11.54.0-1.0-1.3-1.31.2-1.21.2-1.2-1.3-1.3-1.2-1.3-1.0-1.2-1.31.3-1.0-1.31.21.30.70.7-2.0
Conditioned reinforcement - actives0.50.81.00.80.81.0-1.01.0-1.01.01.01.01.01.00.81.01.0-0.90.81.0-0.8-0.9-0.8-0.80.8
Conditioned reinforcement - inactives0.91.42.01.41.11.2-1.31.3-1.31.41.21.21.31.21.11.21.2-1.11.21.3-1.3-0.8-0.8-0.80.6
Conditioned locomotion1.31.72.11.21.21.4-1.41.4-1.41.41.41.41.41.41.11.41.4-1.31.21.3-1.5-1.3-1.0-1.01.4
Patch foraging indifference point 0 sec0.10.21.6-0.7-0.2-0.40.4-0.40.5-0.4-0.3-0.3-0.3-0.3-0.5-0.3-0.20.2-0.5-0.21.20.40.10.1-0.9
Patch foraging indifference point AUC0.91.31.7-1.0-1.2-1.11.1-1.11.1-1.1-1.2-1.1-1.1-1.1-1.1-1.1-1.21.2-1.2-1.30.91.31.31.3-1.0
Delay disc. indifference point, 0s delay0.10.10.8-0.00.20.1-0.10.1-0.10.10.20.20.20.20.00.20.2-0.20.00.30.1-0.4-0.0-0.00.9
Delay disc. indifference point, 16s delay3.84.24.72.02.02.1-2.12.1-2.12.12.12.12.12.12.12.12.1-2.12.12.0-1.9-2.2-2.2-2.21.6
Delay disc. indifference point, 2s delay0.50.60.8-0.8-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8-0.8-0.80.90.50.40.4-0.5
Delay disc. indifference point, 24s delay1.71.93.01.41.21.4-1.41.4-1.41.41.41.41.41.41.41.41.4-1.41.41.4-1.3-1.4-1.1-1.11.7
Delay disc. indifference point, 4s delay0.40.41.00.40.70.6-0.60.6-0.60.60.70.70.70.70.50.70.7-0.70.50.6-0.2-1.0-0.8-0.81.0
Delay disc. indifference point, 8s delay0.91.01.80.81.01.0-1.01.0-1.01.01.01.01.01.00.91.01.0-1.00.91.0-0.8-1.3-1.3-1.31.1
Indifference point function ln k0.00.00.1-0.2-0.1-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.20.1-0.1-0.10.3-0.1-0.2-0.2-0.3
Indifference point function log k0.00.00.1-0.2-0.1-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.20.1-0.1-0.10.3-0.1-0.2-0.2-0.3
Patch foraging total patch changes 0 sec0.40.72.7-1.1-0.6-0.80.8-0.80.9-0.9-0.7-0.7-0.7-0.7-1.0-0.7-0.70.6-1.0-0.61.70.90.60.6-1.3
Patch foraging total patch changes 12 sec0.00.10.3-0.20.10.1-0.00.10.00.00.10.20.10.2-0.20.10.2-0.2-0.20.20.50.30.50.5-0.0
Patch foraging total patch changes 18 sec0.00.00.2-0.10.00.00.00.00.0-0.00.10.10.00.1-0.20.10.1-0.1-0.1-0.00.20.00.30.30.5
Patch foraging total patch changes 24 sec0.50.91.8-1.3-0.9-0.90.9-0.90.9-0.9-0.8-0.8-0.8-0.8-1.2-0.8-0.80.8-1.2-0.91.21.00.90.9-0.9
Patch foraging total patch changes 6 sec0.10.20.70.30.40.4-0.40.4-0.40.40.40.40.40.40.40.40.4-0.40.40.40.10.0-0.4-0.4-0.8
Patch foraging time to switch 0 sec3.47.08.72.62.72.6-2.62.6-2.62.62.62.62.62.62.72.62.6-2.62.72.7-2.7-2.9-2.7-2.72.7
Patch foraging water rate 0 sec1.02.13.2-1.6-1.4-1.41.4-1.41.4-1.4-1.3-1.3-1.3-1.3-1.6-1.3-1.31.3-1.6-1.41.81.61.61.6-1.2
Patch foraging water rate 12 sec3.47.18.7-2.9-2.7-2.72.7-2.72.7-2.7-2.7-2.7-2.7-2.7-2.9-2.7-2.72.7-2.9-2.72.72.52.32.3-2.2
Patch foraging water rate 18 sec2.43.75.6-1.9-2.1-1.91.8-1.81.8-1.8-1.9-1.9-1.9-1.9-1.8-1.9-1.91.9-1.9-2.01.62.32.42.4-1.8
Patch foraging water rate 24 sec0.40.61.9-0.7-0.7-0.70.7-0.70.7-0.7-0.6-0.6-0.7-0.6-0.8-0.7-0.60.6-0.8-0.70.51.01.41.4-0.0
Patch foraging water rate 6 sec0.50.71.5-1.1-0.7-0.70.7-0.70.7-0.7-0.6-0.6-0.6-0.6-1.0-0.6-0.60.6-1.1-0.71.01.11.21.2-0.6
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.5-0.4-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.5-0.3-0.30.3-0.5-0.30.40.30.60.60.3
Distance traveled before self-admin0.10.20.30.30.40.5-0.50.5-0.50.50.50.50.50.50.30.50.5-0.50.50.6-0.4-0.00.10.10.2
Distance traveled after self-admin0.10.10.7-0.0-0.3-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.10.0-0.1-0.10.10.1-0.1-0.30.40.80.80.5
Extensor digitorum longus weight2.811.113.0-3.5-3.5-3.43.4-3.43.4-3.4-3.4-3.4-3.4-3.4-3.5-3.5-3.43.4-3.5-3.52.72.83.63.6-0.7
Bone: elastic displacement2.73.13.81.71.91.9-1.91.9-1.91.91.91.91.91.91.71.91.9-1.91.71.9-1.5-1.4-1.6-1.60.8
Bone: elastic work0.30.41.00.50.60.5-0.50.6-0.50.50.60.60.60.60.50.60.6-0.60.50.6-0.2-0.6-1.0-1.0-0.2
Bone: endosteal estimation1.43.23.5-1.9-1.7-1.81.8-1.81.8-1.8-1.8-1.8-1.8-1.8-1.9-1.8-1.81.8-1.8-1.61.91.81.71.7-1.4
Bone: endosteal perimeter1.02.02.3-1.5-1.4-1.51.5-1.51.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.51.5-1.5-1.31.31.41.41.4-1.0
Epididymis fat weight1.96.58.9-2.7-2.5-2.62.6-2.52.6-2.6-2.5-2.5-2.5-2.5-2.5-2.5-2.52.5-2.6-2.43.02.82.32.3-2.9
Delta time in closed arm before/after self-admin0.00.00.30.10.00.1-0.10.1-0.10.10.10.10.10.10.20.10.1-0.10.10.1-0.10.30.60.60.2
Delta time in open arm before/after self-admin2.42.44.1-1.6-1.5-1.51.5-1.51.5-1.5-1.4-1.4-1.4-1.4-1.7-1.4-1.41.4-1.7-1.41.81.81.41.4-2.0
Diff in mean of infusions in LGA sessions0.20.30.60.40.50.6-0.60.6-0.60.60.60.60.60.60.80.60.6-0.60.80.6-0.30.1-0.1-0.1-0.6
Delay discount exponential model param0.60.71.5-0.6-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.80.9-0.7-0.80.41.21.11.1-1.2
Extinction: sum of active levers before priming0.10.10.40.5-0.00.1-0.20.1-0.20.20.10.00.10.00.30.10.00.00.3-0.0-0.60.40.20.2-0.6
Active lever presses in extinction session 60.50.51.5-0.4-0.9-0.70.7-0.70.6-0.6-0.7-0.8-0.7-0.7-0.4-0.7-0.70.8-0.5-0.80.30.80.50.5-1.2
Bone: final force1.32.12.3-1.5-1.5-1.51.5-1.51.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.51.5-1.5-1.51.51.20.90.9-1.3
Bone: final moment1.11.82.3-1.3-1.4-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.31.41.20.90.9-1.5
Food consumed during 24 hour testing period0.00.00.40.1-0.1-0.00.0-0.0-0.00.0-0.0-0.0-0.0-0.00.1-0.0-0.00.10.2-0.1-0.00.1-0.2-0.2-0.6
Glucose0.20.30.40.50.60.6-0.60.6-0.60.60.60.60.60.60.50.60.6-0.60.50.6-0.3-0.6-0.6-0.60.4
Heart weight0.10.20.4-0.5-0.4-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.40.60.50.30.3-0.6
Delay discount hyperbolic model param0.20.30.8-0.2-0.4-0.40.4-0.40.4-0.4-0.4-0.5-0.4-0.5-0.3-0.5-0.50.5-0.3-0.40.10.90.80.8-0.7
Intermittent access intake day 1-15 change0.40.82.11.00.70.9-1.00.9-1.01.00.90.90.90.90.80.90.9-0.80.80.8-1.5-0.9-0.5-0.51.3
Intermittent access intake escalation0.71.53.11.41.01.3-1.31.3-1.31.31.21.21.21.21.11.21.2-1.11.11.2-1.8-1.2-0.8-0.81.5
Intermittent access intake escalation 21.51.73.91.31.11.3-1.31.3-1.41.41.21.21.21.21.21.21.2-1.11.21.2-2.0-1.4-0.9-0.91.9
Intermitt. access day 1 inactive lever presses0.10.30.50.60.50.6-0.60.6-0.60.60.50.60.50.60.60.50.5-0.50.60.6-0.6-0.4-0.1-0.10.7
Intermitt. access day 15 inactive lever presses0.10.31.20.40.50.5-0.50.5-0.50.50.50.40.50.40.50.50.4-0.40.50.4-0.3-0.7-1.1-1.1-0.3
Intermitt. access escalation Index1.72.43.0-1.5-1.5-1.71.7-1.71.6-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.71.7-1.7-1.71.41.00.80.8-1.0
Intermittent access day 1 total infusions0.20.31.0-0.8-0.6-0.50.6-0.50.6-0.6-0.5-0.5-0.5-0.5-0.6-0.5-0.40.4-0.4-0.51.00.60.40.4-0.7
Intermittent access day 15 total infusions0.10.10.40.40.10.4-0.40.4-0.40.40.40.40.40.40.40.40.4-0.40.40.3-0.7-0.1-0.0-0.00.3
Intermittent access terminal intake (last 3 days)0.00.00.30.1-0.10.2-0.20.2-0.20.20.20.10.20.10.20.20.2-0.10.30.0-0.60.20.20.2-0.1
Intermittent access total infusions0.30.30.6-0.7-0.7-0.50.5-0.50.6-0.6-0.5-0.5-0.5-0.5-0.6-0.5-0.50.5-0.5-0.50.70.70.70.7-0.5
Intermittent access day 1 locomotion0.20.30.7-0.6-0.6-0.50.5-0.50.5-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.3-0.50.70.70.60.6-0.9
Intermittent access day 15 total locomotion0.00.10.3-0.2-0.3-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.4-0.2-0.20.3-0.3-0.30.20.20.00.0-0.5
Intermittent access total locomotion0.10.10.5-0.4-0.4-0.30.3-0.30.3-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.30.50.40.20.2-0.7
Intermittent access standard deviation0.51.01.3-1.1-1.1-1.01.0-1.01.0-1.0-1.1-1.1-1.1-1.1-1.1-1.1-1.11.1-1.1-1.00.80.50.70.7-0.0
Left kidney weight4.119.221.1-4.6-4.6-4.54.5-4.54.5-4.5-4.5-4.5-4.5-4.5-4.5-4.5-4.54.5-4.3-4.43.94.34.54.5-2.9
Right kidney weight6.831.133.9-5.7-5.8-5.75.7-5.75.7-5.7-5.7-5.7-5.7-5.7-5.5-5.7-5.75.7-5.3-5.75.15.65.75.7-4.2
Cocaine induced anxiety0.20.30.5-0.4-0.5-0.60.6-0.60.6-0.6-0.7-0.7-0.7-0.7-0.5-0.7-0.70.7-0.6-0.70.40.30.40.40.1
Post-drug Anxiety0.30.31.10.60.50.3-0.40.3-0.40.40.30.30.30.30.50.30.3-0.30.40.3-0.5-1.0-1.0-1.00.9
Baseline Anxiety1.41.62.71.21.21.2-1.21.2-1.21.21.21.21.21.21.21.21.2-1.21.21.2-1.1-1.6-1.6-1.61.1
Tail length0.10.41.4-0.8-0.3-0.60.6-0.60.6-0.6-0.5-0.5-0.5-0.5-0.8-0.5-0.50.5-0.7-0.31.20.50.40.4-0.5
Length with tail0.10.31.0-0.6-0.4-0.50.5-0.50.5-0.5-0.5-0.4-0.4-0.5-0.6-0.4-0.40.4-0.5-0.40.80.60.30.3-1.0
Length without tail0.10.41.1-0.4-0.8-0.60.5-0.60.5-0.5-0.6-0.6-0.6-0.6-0.4-0.6-0.60.7-0.4-0.80.10.80.60.6-1.0
Times rat made contact with spout0.40.50.80.70.50.8-0.80.8-0.80.80.80.80.80.80.80.80.8-0.80.90.7-0.9-0.3-0.1-0.10.6
Lifetime Intake0.30.40.9-0.9-0.6-0.60.7-0.60.7-0.7-0.6-0.6-0.6-0.6-0.8-0.6-0.60.6-0.7-0.61.00.50.40.4-0.6
Liver weight, left2.94.85.6-2.2-2.4-2.22.2-2.22.1-2.1-2.3-2.3-2.2-2.3-2.0-2.3-2.32.3-2.0-2.31.82.42.32.3-1.9
Liver weight, right1.42.53.1-1.7-1.6-1.61.6-1.61.6-1.6-1.6-1.6-1.6-1.6-1.5-1.6-1.61.6-1.5-1.51.51.61.71.7-1.0
Locomotor activity0.60.93.5-0.9-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.90.9-1.0-0.91.10.80.20.2-1.9
Locomotor testing distance0.10.11.2-0.3-0.0-0.10.1-0.10.1-0.1-0.0-0.0-0.0-0.0-0.4-0.0-0.00.0-0.4-0.10.60.1-0.5-0.5-1.1
Locomotor testing rearing0.10.10.6-0.2-0.2-0.30.3-0.30.3-0.3-0.2-0.2-0.2-0.2-0.3-0.2-0.20.2-0.3-0.20.70.2-0.1-0.1-0.8
Locomotion in novel chamber5.16.57.2-2.7-2.5-2.62.6-2.62.6-2.6-2.6-2.6-2.6-2.6-2.6-2.6-2.62.5-2.6-2.52.72.42.52.5-1.7
Locomotion in novel chamber post-restriction0.10.21.7-0.3-0.2-0.30.3-0.30.2-0.2-0.3-0.3-0.3-0.3-0.2-0.3-0.30.3-0.2-0.30.60.4-0.1-0.1-1.3
Fecal boli incidents, locomotor time 10.10.10.60.20.20.2-0.20.2-0.20.20.20.20.20.20.20.20.2-0.20.20.3-0.10.10.60.60.8
Change in fecal boli incidents, locomotor task0.10.10.7-0.1-0.1-0.20.2-0.20.1-0.1-0.2-0.2-0.2-0.2-0.1-0.2-0.20.2-0.1-0.20.20.2-0.2-0.2-0.8
Time >=10cm from walls, locomotor time 10.80.81.00.90.91.0-1.01.0-1.01.01.01.01.01.00.91.01.0-1.01.00.9-0.7-0.6-0.9-0.9-0.0
Bouts of movement, locomotor time 10.10.10.20.40.20.2-0.20.2-0.20.20.20.10.20.10.40.20.1-0.10.40.1-0.5-0.1-0.0-0.00.3
Total resting periods, locomotor time 10.50.51.10.90.60.7-0.70.7-0.70.70.70.60.70.60.90.60.6-0.60.90.6-1.1-0.7-0.4-0.40.9
Rest time, locomotor task time 13.13.87.01.91.81.9-1.91.9-1.91.91.81.81.81.81.91.81.8-1.81.91.8-2.2-2.5-2.1-2.12.7
Distance moved, locomotor task time 11.31.96.0-1.2-1.4-1.21.2-1.21.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2-1.3-1.31.51.91.31.3-2.5
Vertical activity count, locomotor time 10.00.10.4-0.2-0.2-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.00.0-0.2-0.10.30.70.60.6-0.7
Time >=10cm from walls, locomotor time 20.00.00.1-0.0-0.3-0.20.2-0.20.2-0.2-0.2-0.3-0.2-0.3-0.0-0.2-0.30.3-0.1-0.3-0.30.20.20.2-0.2
Bouts of movement, locomotor time 20.40.71.0-0.9-0.7-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.9-0.8-0.80.8-0.9-0.80.91.00.90.9-1.0
Total resting periods, locomotor time 20.61.01.4-1.0-0.9-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.00.9-1.0-1.00.91.21.21.2-0.9
Rest time, locomotor task time 20.81.11.41.00.91.1-1.11.1-1.11.11.11.11.11.11.01.11.1-1.11.01.2-1.1-0.9-0.6-0.61.2
Distance moved, locomotor task time 20.10.20.50.50.40.4-0.40.4-0.40.40.30.30.30.30.50.30.3-0.30.40.3-0.7-0.5-0.4-0.40.4
Vertical activity count, locomotor time 20.91.31.61.21.21.1-1.11.1-1.11.11.11.11.11.11.21.11.1-1.11.21.1-1.3-1.2-1.0-1.01.2
Light reinforcement 10.40.91.20.81.01.0-1.01.0-1.01.01.01.11.01.10.91.01.1-1.11.01.0-0.7-0.7-0.6-0.60.8
Light reinforcement 20.20.40.50.50.70.7-0.70.7-0.70.70.70.70.70.70.60.70.7-0.70.70.6-0.3-0.4-0.6-0.6-0.1
Bone: marrow area1.32.93.3-1.8-1.6-1.81.8-1.81.8-1.8-1.7-1.7-1.7-1.7-1.8-1.7-1.71.7-1.8-1.51.81.71.61.6-1.3
Bone: maximum diameter2.34.35.3-2.2-2.0-2.22.2-2.22.2-2.2-2.2-2.2-2.2-2.2-2.3-2.2-2.22.1-2.2-2.02.31.51.21.2-1.7
Bone: maximum force0.91.72.0-1.3-1.3-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.3-1.4-1.41.4-1.3-1.31.40.90.50.5-1.4
Bone: maximum moment0.71.32.3-1.1-1.1-1.21.2-1.21.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2-1.1-1.11.30.90.50.5-1.5
Mean time between licks in bursts0.40.92.0-0.9-1.0-1.00.9-1.00.9-0.9-1.1-1.1-1.0-1.1-0.8-1.1-1.11.2-0.8-1.10.10.90.50.5-1.4
Mean num. licks in bursts2.23.43.9-2.0-1.8-1.91.9-1.91.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.91.9-2.0-1.91.91.71.51.5-1.7
Cd content in liver0.50.50.90.60.80.7-0.70.7-0.70.70.80.80.80.80.60.80.8-0.80.60.8-0.0-0.2-0.8-0.8-0.9
Co content in liver1.82.02.61.41.61.4-1.41.4-1.41.41.51.51.51.51.41.51.5-1.51.41.5-1.0-1.4-1.6-1.60.7
Cu content in liver1.61.93.1-1.4-1.4-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.41.41.30.90.9-1.8
Fe content in liver0.20.20.70.50.40.4-0.40.4-0.40.40.30.30.30.30.50.30.3-0.30.50.3-0.5-0.8-0.8-0.80.5
K content in liver1.31.21.7-1.0-1.3-1.21.1-1.21.1-1.1-1.2-1.3-1.2-1.3-1.0-1.2-1.31.3-1.0-1.30.60.80.50.5-1.1
Mg content in liver0.80.81.1-0.9-1.0-1.00.9-1.00.9-0.9-1.0-1.0-1.0-1.0-0.9-1.0-1.01.1-0.9-1.10.60.60.30.3-1.0
Mn content in liver1.41.52.0-1.2-1.4-1.31.3-1.31.3-1.3-1.4-1.4-1.4-1.4-1.2-1.4-1.41.4-1.2-1.40.80.91.01.0-0.6
Na content in liver1.31.41.8-1.2-1.3-1.31.3-1.31.3-1.3-1.3-1.3-1.3-1.3-1.2-1.3-1.31.4-1.2-1.41.00.50.30.3-0.9
Rb content in liver0.10.22.00.10.20.1-0.20.2-0.20.20.20.10.20.10.10.20.1-0.10.10.10.1-0.1-0.8-0.8-1.4
Se content in liver0.60.71.1-0.7-1.0-0.90.9-0.90.9-0.9-1.0-1.0-1.0-1.0-0.7-1.0-1.01.0-0.7-1.00.50.50.40.4-0.4
Sr content in liver2.42.12.9-1.4-1.5-1.41.4-1.41.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.4-1.4-1.41.31.51.71.7-0.7
Zn content in liver1.41.62.9-1.4-1.1-1.21.2-1.21.3-1.2-1.2-1.2-1.2-1.2-1.4-1.2-1.21.2-1.4-1.21.61.20.70.7-1.7
Bone: minimum diameter0.81.42.4-1.3-1.1-1.21.3-1.21.3-1.3-1.2-1.2-1.2-1.2-1.4-1.2-1.21.2-1.3-1.01.60.80.60.6-1.0
Time in familiar zone, hab. session 10.30.30.50.60.50.6-0.60.6-0.60.60.60.60.60.60.60.60.6-0.50.60.5-0.7-0.2-0.2-0.20.2
Time in novel zone, hab. session 10.20.20.4-0.4-0.3-0.40.5-0.40.5-0.5-0.4-0.4-0.4-0.4-0.5-0.4-0.40.4-0.5-0.30.60.40.20.2-0.6
Total zone transitions, hab. session 10.10.21.1-0.2-0.4-0.30.3-0.30.3-0.3-0.3-0.4-0.3-0.4-0.1-0.3-0.40.4-0.1-0.50.30.1-0.5-0.5-1.1
Total locomotion distance, hab. session 10.50.84.2-0.8-0.8-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.80.8-0.7-0.91.10.7-0.2-0.2-2.0
Locomotion velocity, hab. session 10.60.84.0-0.8-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.90.9-0.8-1.01.10.6-0.2-0.2-2.0
Time in familiar zone, hab. session 20.50.51.3-0.9-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.70.80.80.50.5-1.1
Time in novel zone, hab. session 20.00.00.20.20.10.1-0.00.0-0.00.00.10.10.10.10.10.10.1-0.10.10.1-0.1-0.10.00.00.4
Total zone transitions, hab. session 20.20.32.1-0.3-0.4-0.40.4-0.40.4-0.4-0.5-0.5-0.4-0.5-0.3-0.4-0.50.5-0.3-0.50.40.2-0.5-0.5-1.4
Total locomotion distance, hab. session 20.10.11.4-0.1-0.1-0.10.1-0.10.1-0.1-0.2-0.2-0.1-0.20.0-0.2-0.20.20.0-0.20.1-0.1-0.8-0.8-1.2
Locomotion velocity, hab. session 20.10.21.5-0.1-0.1-0.20.1-0.10.1-0.1-0.2-0.2-0.2-0.2-0.0-0.2-0.20.2-0.0-0.20.1-0.2-0.9-0.9-1.2
Novel to familiar place preference ratio0.30.40.50.70.50.6-0.60.6-0.70.70.60.60.60.60.70.60.6-0.50.70.5-0.7-0.3-0.6-0.6-0.5
Novelty place preference0.60.61.00.90.70.8-0.90.8-0.90.90.80.80.80.80.80.80.8-0.70.80.7-1.0-0.4-0.7-0.7-0.1
Time in novel zone, NPP test0.40.40.70.80.60.7-0.70.7-0.80.80.70.60.70.60.70.70.6-0.60.70.5-0.8-0.1-0.5-0.5-0.5
Total zone transitions, NPP test0.00.10.2-0.1-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.20.2-0.1-0.20.3-0.2-0.5-0.5-0.4
Total locomotion distance, NPP test0.20.21.40.30.40.2-0.20.2-0.20.20.20.20.20.20.40.20.2-0.20.40.2-0.1-0.8-1.2-1.2-0.1
Locomotion velocity, NPP test0.10.21.20.20.30.2-0.20.2-0.20.20.20.20.20.20.30.20.2-0.20.30.2-0.1-0.8-1.1-1.10.1
Intraocular pressure0.30.40.6-0.7-0.7-0.70.7-0.70.8-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.70.7-0.6-0.70.70.40.60.60.1
Delta distance traveled before/after self-admin0.30.30.5-0.4-0.7-0.60.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.4-0.6-0.60.6-0.5-0.70.40.30.40.4-0.2
Delta ambulatory time before/after self-admin0.20.30.4-0.3-0.6-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.3-0.6-0.60.6-0.4-0.60.20.30.70.70.3
Parametrial fat weight7.217.018.0-4.1-4.2-4.24.2-4.24.2-4.2-4.1-4.1-4.1-4.1-4.2-4.1-4.14.1-4.2-4.14.14.24.04.0-3.6
Pavlov. Cond. lever latency1.31.62.31.31.51.4-1.41.4-1.41.41.41.41.41.41.31.41.4-1.41.31.5-1.0-0.5-0.8-0.8-0.1
Pavlov. Cond. magazine entry latency6.98.910.1-2.9-3.2-3.13.1-3.13.1-3.1-3.1-3.1-3.1-3.1-2.9-3.1-3.13.1-2.9-3.12.72.73.03.0-1.7
Pavlov. Cond. change in total contacts2.32.42.8-1.7-1.7-1.61.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.6-1.7-1.71.7-1.6-1.71.20.91.51.50.4
Pavlov. Cond. index score4.55.66.7-2.4-2.6-2.52.5-2.52.5-2.5-2.5-2.5-2.5-2.5-2.3-2.5-2.52.5-2.3-2.61.91.92.22.2-0.8
Pavlov. Cond. latency score4.25.46.4-2.3-2.5-2.52.4-2.52.4-2.4-2.5-2.5-2.5-2.5-2.3-2.5-2.52.5-2.3-2.51.91.82.12.1-0.8
Pavlov. Cond. lever contacts2.83.44.3-1.9-2.0-2.02.0-2.02.0-2.0-2.0-2.0-2.0-2.0-1.9-2.0-2.02.0-1.9-2.11.61.21.51.5-0.4
Pavlov. Cond. magazine entry number4.15.26.12.12.52.4-2.42.4-2.42.42.42.42.42.42.12.42.4-2.42.12.4-1.8-2.0-2.4-2.40.8
Pavlov. Cond. intertrial magazine entries0.40.51.70.60.70.6-0.60.6-0.60.60.70.70.70.60.70.70.7-0.70.70.7-0.4-0.9-1.3-1.3-0.1
Pavlov. Cond. lever-magazine prob. diff.4.85.96.9-2.4-2.6-2.62.6-2.62.6-2.6-2.6-2.6-2.6-2.6-2.4-2.6-2.62.6-2.4-2.62.11.92.32.3-0.9
Pavlov. Cond. response bias2.93.64.5-1.8-2.1-2.02.0-2.02.0-2.0-2.0-2.0-2.0-2.0-1.8-2.0-2.02.1-1.8-2.11.31.51.91.9-0.5
Pavlov. Cond. lever latency2.94.06.92.11.92.0-2.12.0-2.12.12.02.02.02.02.12.02.0-1.92.21.9-2.6-1.7-1.0-1.02.5
Pavlov. Cond. magazine entry latency0.10.10.2-0.4-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.40.2-0.20.00.00.5
Pavlov. Cond. change in total contacts0.81.33.9-1.1-1.0-1.11.1-1.11.1-1.1-1.1-1.0-1.0-1.0-1.2-1.0-1.01.0-1.3-1.01.71.00.30.3-2.0
Pavlov. Cond. index score1.11.42.3-1.3-1.2-1.21.2-1.21.3-1.3-1.2-1.2-1.2-1.2-1.3-1.2-1.21.2-1.3-1.21.50.90.60.6-1.2
Pavlov. Cond. latency score0.91.21.8-1.2-1.0-1.11.1-1.11.2-1.1-1.1-1.1-1.1-1.1-1.2-1.1-1.11.1-1.2-1.11.40.70.60.6-0.9
Pavlov. Cond. lever contacts3.64.98.1-2.4-2.1-2.32.3-2.32.3-2.3-2.2-2.2-2.2-2.2-2.4-2.2-2.22.2-2.5-2.12.81.91.31.3-2.5
Pavlov. Cond. magazine entry number0.30.31.2-0.4-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.50.5-0.4-0.40.30.91.11.1-0.5
Pavlov. Cond. intertrial magazine entries6.39.510.9-2.9-3.3-3.23.1-3.13.1-3.1-3.2-3.2-3.2-3.2-2.9-3.2-3.23.2-2.8-3.22.63.23.13.1-2.7
Pavlov. Cond. lever-magazine prob. diff.0.91.22.1-1.2-1.1-1.11.2-1.11.2-1.2-1.1-1.1-1.1-1.1-1.2-1.1-1.11.1-1.2-1.11.40.80.50.5-1.0
Pavlov. Cond. response bias1.72.33.8-1.5-1.4-1.61.6-1.51.6-1.6-1.5-1.5-1.5-1.5-1.6-1.5-1.51.5-1.7-1.52.01.20.70.7-1.9
Time in closed arm before self-admin0.20.30.7-0.8-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.8-0.5-0.50.5-0.7-0.50.80.1-0.0-0.0-0.2
Time in closed arm after self-admin0.30.31.10.30.50.6-0.50.6-0.50.50.60.60.60.60.50.60.6-0.70.50.6-0.3-0.40.00.01.1
Time in open arm before self-admin0.10.10.40.50.40.3-0.30.3-0.30.30.30.30.30.30.60.30.2-0.20.60.2-0.6-0.4-0.2-0.20.5
Time in open arm after self-admin2.62.84.5-1.3-1.8-1.61.6-1.61.6-1.6-1.7-1.7-1.7-1.7-1.5-1.7-1.71.7-1.5-1.71.12.12.02.0-1.8
Bone: periosteal estimation1.94.05.9-2.2-1.8-2.12.1-2.12.2-2.1-2.1-2.0-2.1-2.0-2.2-2.0-2.02.0-2.2-1.82.41.61.41.4-1.6
Bone: periosteal perimeter2.44.25.2-2.2-2.0-2.22.2-2.12.2-2.2-2.1-2.1-2.1-2.1-2.2-2.1-2.12.1-2.2-2.02.31.81.41.4-1.9
Bone: post-yield work4.16.09.0-2.4-2.5-2.52.5-2.52.5-2.5-2.5-2.5-2.5-2.5-2.4-2.5-2.52.5-2.4-2.42.52.51.81.8-3.0
Progressive ratio test 1 active lever presses0.70.81.5-1.2-1.0-0.90.9-0.90.9-0.9-0.8-0.8-0.8-0.8-1.1-0.8-0.80.8-0.9-0.81.21.01.01.0-0.7
Progressive ratio test 1 breakpoint0.60.71.3-1.1-0.9-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.7-1.0-0.8-0.70.7-0.9-0.71.10.91.01.0-0.6
Progressive ratio test 1 inactive lever presses0.20.30.7-0.6-0.4-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.4-0.6-0.4-0.50.5-0.5-0.40.80.70.50.5-0.8
Progressive ratio test 2 active lever presses0.00.00.3-0.6-0.1-0.10.1-0.10.1-0.1-0.1-0.0-0.1-0.1-0.3-0.1-0.00.0-0.2-0.00.5-0.00.10.10.2
Progressive ratio test 2 breakpoint0.00.00.3-0.5-0.0-0.10.1-0.10.1-0.1-0.0-0.0-0.0-0.0-0.2-0.0-0.0-0.0-0.20.00.5-0.10.00.00.2
Progressive ratio test 2 inactive lever presses0.10.20.5-0.5-0.4-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.5-0.3-0.30.3-0.4-0.30.60.50.30.3-0.7
Incentive Sensitization - Responses0.50.71.10.41.00.9-0.90.9-0.80.90.90.90.90.90.60.90.9-0.90.70.9-0.5-1.0-1.0-1.00.9
Incentive Sensitization - Breakpoint0.50.60.90.30.90.8-0.80.8-0.80.80.80.80.80.80.60.80.8-0.80.60.8-0.4-1.0-1.0-1.00.7
Sum of active levers in priming session hrs 5-60.10.11.40.1-0.2-0.20.2-0.20.2-0.2-0.2-0.3-0.2-0.30.2-0.2-0.30.30.2-0.30.10.50.10.1-1.2
Progressive ratio0.00.10.9-0.2-0.1-0.0-0.00.0-0.10.1-0.0-0.00.0-0.0-0.10.0-0.00.0-0.10.00.10.2-0.3-0.3-1.0
Food seeking constrained by brief footshock0.20.30.60.70.30.6-0.60.6-0.70.70.60.50.60.60.60.60.5-0.50.60.6-0.8-0.2-0.1-0.10.5
Seeking ratio, punishment vs. effort0.10.11.10.2-0.1-0.00.0-0.00.0-0.0-0.0-0.0-0.0-0.00.1-0.0-0.00.00.1-0.0-0.30.00.60.61.0
Retroperitoneal fat weight7.029.931.8-5.5-5.5-5.55.5-5.55.5-5.5-5.5-5.5-5.5-5.5-5.4-5.5-5.55.5-5.5-5.45.55.65.35.3-4.9
Reaction time number correct0.30.71.6-1.0-0.9-0.70.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.9-0.7-0.70.7-0.9-0.70.60.81.31.30.1
Reaction time mean minus median0.41.01.5-1.2-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.1-1.2-1.0-1.11.1-1.2-1.11.00.60.40.4-0.8
Reaction time mean minus median AUC0.51.21.9-1.4-1.1-1.21.1-1.11.1-1.1-1.2-1.2-1.2-1.2-1.3-1.2-1.21.2-1.3-1.21.00.70.50.5-1.1
Reaction time num false alarms0.30.41.30.60.40.6-0.60.6-0.60.60.50.50.50.60.60.50.5-0.50.60.5-1.0-0.4-0.0-0.01.2
Reaction time num false alarms AUC0.10.10.60.30.00.2-0.20.2-0.20.20.10.10.20.20.30.10.1-0.10.40.0-0.7-0.10.30.30.8
Reaction time trials correct on left0.30.71.6-1.0-0.9-0.70.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.9-0.7-0.70.7-0.9-0.70.60.81.31.30.1
Reaction time trials on left0.40.71.6-1.1-0.9-0.70.8-0.80.8-0.8-0.7-0.7-0.8-0.7-1.0-0.8-0.70.7-0.9-0.80.70.91.31.30.1
Reaction time mean0.10.20.5-0.6-0.3-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.40.4-0.4-0.40.70.40.20.2-0.6
Reaction time mean AUC0.00.10.2-0.4-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.20.2-0.2-0.20.50.20.00.0-0.5
Median of all reaction times0.00.00.3-0.20.0-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.00.0-0.1-0.00.50.20.10.1-0.5
Reaction time omissions0.40.51.6-0.9-0.6-0.70.7-0.70.7-0.7-0.6-0.6-0.6-0.6-0.9-0.6-0.60.6-0.8-0.71.20.50.10.1-1.2
Reaction time false alarm rate0.40.61.41.00.70.7-0.80.8-0.80.80.70.70.70.71.00.70.7-0.61.00.6-1.2-0.7-0.5-0.50.9
Reaction time premature initiation rate0.00.00.2-0.2-0.2-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.3-0.1-0.10.1-0.3-0.1-0.1-0.00.20.20.4
Reaction time premature initiations0.10.20.7-0.6-0.5-0.30.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.6-0.4-0.40.4-0.5-0.40.00.40.80.80.6
Std. dev. reaction times0.61.11.7-1.3-1.0-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.2-1.1-1.11.1-1.2-1.11.30.70.50.5-1.0
Reaction time trials completed0.40.71.6-1.1-0.9-0.70.8-0.80.8-0.8-0.7-0.7-0.8-0.7-1.0-0.8-0.70.7-0.9-0.80.70.91.31.30.1
Reaction time trials AUC0.51.02.2-1.2-1.0-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.9-1.1-0.9-0.90.9-1.1-0.90.81.11.51.5-0.0
Run reversals in cocaine runway, females1.41.42.1-1.2-1.1-1.21.2-1.21.3-1.3-1.2-1.2-1.3-1.2-1.2-1.2-1.21.2-1.2-1.11.00.91.41.40.2
Run reversals in cocaine runway, males2.12.12.41.41.51.5-1.51.5-1.51.51.51.51.51.51.41.51.5-1.51.41.5-1.3-1.3-1.2-1.21.2
Latency to leave start box in cocaine runway0.00.00.2-0.20.10.1-0.10.1-0.10.10.10.10.10.1-0.20.10.2-0.2-0.20.10.4-0.1-0.2-0.2-0.0
Latency to leave start box in cocaine runway, F0.20.30.5-0.6-0.4-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.50.70.70.70.7-0.5
Latency to leave start box in cocaine runway, M0.70.61.30.40.80.8-0.80.8-0.70.80.80.80.80.80.40.80.8-0.90.40.9-0.2-1.1-1.1-1.10.8
Std. dev. time between licks in bursts2.43.33.8-1.9-1.8-1.91.9-1.91.9-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.92.0-1.8-1.91.51.61.51.5-1.4
Total sessions with >9 infusions1.72.04.3-1.7-1.3-1.41.4-1.41.5-1.4-1.3-1.3-1.3-1.3-1.7-1.3-1.31.2-1.5-1.22.11.41.41.4-1.2
Short access day 1 total inactive lever presses0.30.50.90.60.70.6-0.60.7-0.60.60.70.70.70.70.60.70.7-0.70.70.80.0-0.8-0.9-0.90.3
Short access day 10 total inactive lever presses1.84.58.12.02.22.0-2.02.0-2.02.02.02.02.02.02.12.02.0-2.02.12.1-1.5-2.7-2.8-2.81.8
Short access day 1 total infusions0.10.10.9-0.5-0.2-0.30.4-0.30.4-0.4-0.3-0.3-0.3-0.3-0.6-0.3-0.30.2-0.5-0.20.90.1-0.0-0.0-0.3
Short access day 10 total infusions0.20.30.8-0.9-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.8-0.5-0.40.4-0.7-0.40.90.50.50.5-0.4
Short access total infusions0.70.92.3-1.3-0.8-0.91.0-0.91.0-1.0-0.9-0.9-0.9-0.9-1.3-0.9-0.90.8-1.1-0.81.50.50.30.3-0.7
Short access day 1 locomotion0.10.10.30.10.30.4-0.40.4-0.30.30.40.40.40.50.10.40.5-0.50.20.50.1-0.00.10.10.3
Short access day 10 total locomotion1.32.43.7-1.6-1.6-1.61.5-1.61.5-1.5-1.6-1.6-1.6-1.6-1.9-1.6-1.61.6-1.8-1.51.41.41.21.2-1.4
Short access total locomotion1.72.03.0-1.6-1.4-1.41.4-1.31.4-1.4-1.3-1.3-1.3-1.3-1.6-1.3-1.31.2-1.5-1.21.71.61.51.5-1.5
One hour access (0.3 mA shock)0.40.50.9-0.5-0.9-0.60.6-0.60.6-0.6-0.7-0.7-0.7-0.7-0.9-0.7-0.70.8-0.8-0.80.20.80.80.8-0.7
Compulsive drug intake0.30.31.0-0.3-0.6-0.50.5-0.60.5-0.5-0.6-0.6-0.6-0.6-0.4-0.6-0.60.6-0.5-0.70.30.80.50.5-1.0
One hour access (shock baseline)0.00.00.30.3-0.00.2-0.30.2-0.30.30.20.20.20.20.00.20.2-0.10.10.1-0.6-0.1-0.1-0.10.1
Social response proportion1.31.43.1-1.1-1.2-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.11.1-0.9-1.10.91.81.51.5-1.8
Social responses0.20.30.50.50.50.6-0.60.6-0.60.60.60.60.60.60.60.60.6-0.60.70.6-0.20.1-0.2-0.2-0.5
Social time0.20.31.20.70.40.5-0.60.6-0.70.60.50.50.50.50.80.50.5-0.40.80.5-1.10.1-0.2-0.2-0.7
Soleus weight1.64.75.1-2.2-2.3-2.22.2-2.22.2-2.2-2.2-2.2-2.2-2.2-2.2-2.2-2.22.2-2.2-2.22.02.12.22.2-1.3
Bone: stiffness0.40.70.9-0.9-0.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.90.9-0.9-0.91.00.40.20.2-0.7
Tibialis anterior weight4.715.917.3-4.1-4.1-4.14.1-4.14.1-4.1-4.0-4.0-4.0-4.0-4.1-4.0-4.04.0-4.2-4.03.83.94.04.0-2.7
Time to tail flick, vehicle, before self-admin0.80.81.1-0.8-0.9-1.01.0-1.01.0-1.0-1.0-1.0-1.0-1.0-0.9-1.0-1.01.1-1.0-1.00.80.30.00.0-0.7
Time to tail flick, vehicle, after self-admin1.41.92.11.31.41.4-1.41.4-1.41.41.41.41.41.41.11.41.4-1.41.31.4-1.3-1.4-1.4-1.41.0
Time to tail flick, test, before self-admin0.00.00.1-0.1-0.2-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.10.0-0.1-0.10.1-0.1-0.10.30.10.00.0-0.2
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.4-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.0-0.3-0.30.3-0.1-0.30.10.10.40.40.4
Delta time to tail flick, vehicle, before/after SA0.30.30.50.10.70.6-0.50.5-0.50.50.60.60.60.60.20.60.6-0.70.30.70.0-0.3-0.4-0.40.2
Delta time to tail flick, test, before/after SA0.50.51.0-0.9-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.5-0.7-0.70.7-0.4-0.60.50.81.01.0-0.1
Tibia length0.10.41.0-0.6-0.6-0.60.5-0.60.5-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.60.6-0.5-0.60.30.80.60.6-1.0
Ambulatory time before self-admin0.60.81.10.80.81.0-1.01.0-1.01.01.01.01.01.00.91.01.0-1.01.11.0-1.0-0.4-0.2-0.20.7
Ambulatory time after self-admin0.20.21.20.40.10.4-0.40.4-0.40.40.30.30.30.40.50.30.3-0.30.60.3-0.7-0.00.60.61.1
Bone: tissue strength0.10.10.50.50.20.4-0.40.4-0.40.40.30.30.30.30.50.30.3-0.30.50.2-0.7-0.2-0.3-0.30.1
Total heroin consumption0.50.61.41.20.70.8-0.80.8-0.90.90.70.70.80.70.80.70.7-0.60.90.6-1.1-0.2-0.5-0.5-0.4
Bone: trabecular number0.10.10.6-0.2-0.4-0.20.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.30.20.70.80.8-0.4
Bone: trabecular spacing0.10.20.2-0.4-0.3-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.30.30.20.40.40.4
Bone: trabecular thickness1.01.33.7-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.11.1-1.1-1.11.21.20.60.6-1.9
Bone: trabecular tissue density0.50.71.00.80.90.8-0.80.8-0.80.80.80.80.80.80.80.80.8-0.80.80.8-0.7-1.0-1.0-1.00.9
Water consumed over 24 hours3.14.16.12.21.82.1-2.12.1-2.12.12.12.12.12.12.12.12.1-2.12.32.0-2.5-1.5-1.0-1.02.2
Number of responses in last shaping day0.00.00.1-0.1-0.3-0.10.1-0.10.1-0.1-0.1-0.1-0.1-0.10.0-0.1-0.00.00.1-0.20.10.10.20.20.1