Pld1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio NM_001399082.1 0.03 0.03 9.2e-03 0 0 0.01 0 1.5e-01 1.8e-01 7.7e-02 2.4e-01
2 Adipose mRNA stability Pld1 0.05 0.04 5.1e-04 0.01 0.02 0.02 0.02 1.1e-02 8.8e-04 4.7e-03 3.6e-03
3 Adipose intron excision ratio chr2_112908612_112915227 0.02 0.02 7.1e-03 0.01 0 0.01 0.01 6.6e-02 1.4e-01 3.3e-02 6.4e-02
4 NAcc intron excision ratio chr2_112907725_112915227 0.06 0.06 6.9e-04 0.01 0.01 0.01 0.02 3.0e-03 3.0e-03 2.8e-02 4.8e-04
5 NAcc gene expression Pld1 0.05 0.03 4.4e-08 0.05 0.06 0.05 0.05 1.6e-08 6.7e-09 2.8e-08 2.2e-08
6 BLA gene expression Pld1 0.07 0.05 3.1e-03 0.02 0.03 0.03 0.03 1.9e-02 1.2e-02 1.0e-02 8.3e-03
7 NAcc isoform ratio NM_001399082.1 0.02 0.01 2.2e-04 0.03 0.02 0.01 0.02 7.1e-05 1.4e-04 2.5e-03 1.4e-04
8 Liver gene expression Pld1 0.33 0.12 0.0e+00 0.26 0.27 0.28 0.27 4.0e-28 5.0e-30 1.3e-30 4.8e-30
9 pVTA alternative TSS XM_006232206.5 0.03 0.03 3.9e-03 0.04 0.03 0.03 0.03 8.3e-04 1.3e-03 3.7e-03 1.3e-03
10 pVTA alternative TSS NM_001399082.1 0.03 0.03 4.7e-03 0.03 0.03 0.02 0.03 2.7e-03 1.7e-03 4.9e-03 1.8e-03
11 OFC gene expression Pld1 0.15 0.11 5.1e-03 0.13 0.07 0.09 0.09 6.2e-04 1.0e-02 4.2e-03 4.0e-03
12 Brain alternative TSS NM_001399082.1 0.03 0.02 2.5e-03 0.01 0.01 0.01 0.01 7.9e-02 1.3e-02 8.7e-02 6.4e-02
13 Brain alternative TSS XM_006232206.5 0.03 0.02 2.7e-03 0.01 0.01 0 0.01 8.1e-02 1.3e-02 1.0e-01 7.4e-02
14 PL gene expression Pld1 0.04 0.03 8.5e-05 0.02 0.01 0.03 0.01 3.3e-03 7.3e-03 2.6e-04 1.2e-02
15 PL isoform ratio NM_001399082.1 0.03 0.02 3.2e-03 0.01 0.02 0.02 0.01 4.9e-02 3.0e-03 5.4e-03 1.6e-02
16 pVTA intron excision ratio chr2_112778078_112790593 0.06 0.04 3.9e-03 0.03 0.03 0.02 0.03 9.3e-04 3.5e-03 1.2e-02 2.0e-03
17 PL mRNA stability Pld1 0.09 0.05 5.3e-08 0.05 0.07 0.07 0.06 1.4e-06 3.6e-08 5.3e-08 2.2e-07
18 Brain mRNA stability Pld1 0.15 0.08 1.1e-10 0.11 0.11 0.11 0.1 2.8e-10 3.1e-10 4.4e-10 5.6e-10
19 Adipose isoform ratio XM_006232206.5 0.06 0.04 4.8e-06 0.05 0.04 0.04 0.04 6.9e-06 2.0e-05 1.8e-05 8.5e-06
20 Adipose alternative TSS NM_001399082.1 0.08 0.05 1.4e-07 0.06 0.05 0.05 0.05 6.0e-07 2.5e-06 3.1e-06 2.6e-06
21 Adipose alternative TSS XM_006232206.5 0.08 0.05 1.5e-07 0.06 0.05 0.05 0.05 6.2e-07 3.0e-06 3.9e-06 3.0e-06
22 Adipose intron excision ratio chr2_112778078_112790593 0.13 0.07 4.2e-13 0.1 0.09 0.09 0.1 2.0e-11 1.7e-10 2.0e-10 1.0e-10
23 Adipose intron excision ratio chr2_112778422_112790593 0.12 0.07 2.4e-12 0.1 0.09 0.09 0.09 1.0e-10 2.9e-10 5.4e-10 5.5e-10
24 Adipose intron excision ratio chr2_112907725_112915227 0.05 0.04 6.1e-05 0.04 0.03 0.03 0.03 8.6e-05 1.2e-04 6.9e-04 1.2e-04
25 Adipose gene expression Pld1 0.33 0.15 0.0e+00 0.18 0.19 0.19 0.19 9.2e-20 6.1e-21 1.1e-20 6.8e-21
26 BLA mRNA stability Pld1 0.23 0.11 2.2e-07 0.12 0.12 0.12 0.12 4.9e-07 5.4e-07 8.9e-07 4.0e-07
27 Brain gene expression Pld1 0.06 0.04 4.1e-04 0.03 0.03 0.04 0.03 7.0e-04 4.6e-04 9.0e-05 1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.71.34.71.7-1.80.51.6-2.0-1.70.7-1.1-0.8-0.70.5-0.40.42.2-1.8-1.01.6-0.60.8-0.50.5-0.50.5-0.5-1.20.80.7
Area under the delay curve1.32.017.90.4-0.81.60.7-1.2-0.8-0.30.00.30.40.50.7-0.74.2-1.6-1.81.6-1.61.8-1.51.5-1.51.5-1.5-1.41.2-0.3
BMI with tail0.20.72.51.1-0.6-0.90.8-0.5-0.51.1-0.6-0.7-0.91.6-0.90.9-0.20.21.0-0.40.7-1.00.7-0.70.7-0.70.70.5-1.5-0.1
BMI without tail0.10.51.41.2-0.80.50.8-1.0-0.60.1-0.30.1-0.11.00.2-0.21.0-1.1-0.81.1-0.70.8-0.70.7-0.70.7-0.7-1.00.20.0
Body weight0.20.82.10.7-0.0-0.7-0.10.20.01.0-0.1-0.6-0.70.5-0.90.9-0.70.90.8-1.01.3-0.91.3-1.31.3-1.31.31.0-1.5-0.0
Weight adjusted by age0.51.54.2-1.92.00.5-1.82.11.8-1.31.51.11.1-1.00.7-0.7-1.41.8-0.1-1.40.40.10.6-0.60.6-0.60.61.2-0.5-1.5
Bone surface0.20.41.00.3-0.2-0.30.3-0.0-0.30.7-0.3-0.6-0.60.7-0.70.70.60.50.6-0.60.8-0.61.0-1.01.0-1.01.00.7-0.7-0.7
Bone volume0.10.22.1-0.0-0.00.9-0.0-0.10.1-0.20.30.20.2-0.10.3-0.31.4-0.2-0.50.3-0.30.4-0.10.1-0.10.1-0.1-0.30.3-1.0
Breakpoint value in progressive ratio session0.51.03.60.5-0.71.00.2-0.8-0.4-0.10.00.60.4-0.70.6-0.61.9-1.4-0.51.6-1.30.4-1.21.2-1.21.2-1.2-1.61.5-0.1
Number of licking bursts0.10.41.0-0.70.80.7-0.90.71.0-0.80.90.80.8-0.60.7-0.7-0.50.4-0.5-0.2-0.10.7-0.30.3-0.30.3-0.3-0.10.1-0.8
Context. condit. distance diff. score2.53.18.12.6-2.7-1.72.5-2.5-2.62.1-2.7-2.2-2.11.8-1.81.80.2-1.61.11.10.3-1.20.5-0.50.5-0.50.5-0.6-0.02.8
Locomotion velocity, session 12.42.75.9-0.70.9-1.5-0.61.30.50.5-0.4-0.9-0.80.9-1.21.2-2.42.22.0-2.31.8-2.02.2-2.22.2-2.22.22.4-2.1-0.0
Locomotion distance, session 11.82.34.7-0.10.3-1.7-0.10.70.00.9-0.7-1.2-1.11.1-1.41.4-2.21.62.0-1.91.9-2.01.9-1.91.9-1.91.92.0-1.90.2
Locomotion velocity, session 20.91.13.2-1.01.3-0.8-1.01.51.1-0.10.60.10.1-0.3-0.20.2-1.81.71.3-1.61.1-1.40.9-0.90.9-0.90.91.4-1.2-1.0
Locomotion distance, session 20.91.22.8-0.60.8-0.8-0.61.10.60.40.1-0.4-0.40.2-0.70.7-1.21.61.3-1.71.6-1.41.4-1.41.4-1.41.41.7-1.5-0.8
Locomotion velocity, session 30.10.10.9-0.50.20.2-0.10.20.00.0-0.1-0.1-0.10.0-0.10.1-0.40.30.9-0.30.1-0.90.3-0.30.3-0.30.30.3-0.20.0
Locomotion distance, session 30.40.51.4-0.50.4-0.3-0.20.60.20.3-0.1-0.4-0.40.3-0.50.5-0.60.91.2-1.00.8-1.20.9-0.90.9-0.90.91.0-0.8-0.1
Stereotopy head waving bouts, day 30.10.10.3-0.20.10.00.00.20.1-0.0-0.2-0.2-0.20.4-0.30.3-0.10.50.2-0.50.3-0.40.5-0.50.5-0.50.50.5-0.5-0.2
Stereotopy head waving duration, day 30.30.41.20.9-1.0-0.10.9-1.0-0.80.4-0.8-0.5-0.40.5-0.30.30.4-0.9-0.70.8-0.30.4-0.20.2-0.20.2-0.2-0.60.31.1
Locomotion velocity, session 70.20.20.9-0.20.1-0.9-0.10.3-0.00.1-0.3-0.3-0.2-0.1-0.30.3-0.90.40.6-0.40.6-0.90.4-0.40.4-0.40.40.4-0.10.4
Locomotion distance, session 70.70.91.9-0.90.50.8-0.80.30.7-1.30.71.01.1-1.41.2-1.21.1-0.5-1.00.8-1.11.0-1.01.0-1.01.0-1.0-0.91.40.1
Stereotopy head waving bouts, day 70.81.02.60.8-0.7-1.40.8-0.5-0.71.3-1.1-1.0-1.21.0-1.21.2-1.10.21.4-0.40.9-1.60.9-0.90.9-0.90.90.6-1.00.9
Stereotopy head waving duration, day 71.41.73.31.4-1.4-1.61.6-1.1-1.41.8-1.7-1.6-1.71.8-1.71.7-0.8-0.21.4-0.21.0-1.51.0-1.01.0-1.01.00.5-1.11.1
Locomotion velocity, session 80.91.13.01.2-0.9-1.40.9-0.7-0.81.2-1.1-1.3-1.30.9-1.31.3-1.5-0.01.3-0.30.8-1.70.9-0.90.9-0.90.90.5-1.00.7
Locomotion distance, session 80.91.42.61.3-1.1-1.51.2-0.9-1.11.4-1.5-1.5-1.51.3-1.51.5-0.7-0.11.4-0.30.9-1.61.0-1.01.0-1.01.00.5-0.91.3
Degree of sensitization distance1.82.03.2-1.20.81.4-1.10.51.1-1.81.31.61.7-1.61.7-1.71.0-0.5-1.81.0-1.61.8-1.61.6-1.61.6-1.6-1.21.6-0.4
Degree of sensitization stereotypy1.31.53.31.5-1.5-1.61.6-1.3-1.51.8-1.7-1.4-1.61.5-1.51.5-0.6-0.61.30.20.6-1.40.6-0.60.6-0.60.60.1-0.71.5
Conditioned locomotion1.61.95.5-0.1-0.31.90.1-0.7-0.1-0.90.70.80.9-0.81.2-1.22.3-1.5-1.71.7-1.71.6-1.71.7-1.71.7-1.7-1.71.6-0.5
Cocaine response after cond. corrected1.01.53.3-1.00.61.8-0.80.30.8-1.61.21.21.4-1.61.5-1.50.8-0.6-1.80.8-1.21.7-1.31.3-1.31.3-1.3-1.01.5-0.5
Cocaine response after cond. not corrected0.81.12.8-1.61.11.7-1.10.91.1-1.61.31.11.3-1.61.3-1.30.50.2-1.00.1-0.81.0-0.70.7-0.70.7-0.7-0.31.0-1.1
Cocaine response before conditioning1.21.43.60.3-0.2-1.30.50.1-0.61.1-1.0-1.2-1.21.0-1.41.4-0.81.01.9-1.21.3-1.71.5-1.51.5-1.51.51.4-1.3-0.2
Saline control response0.10.10.4-0.2-0.10.20.3-0.1-0.40.3-0.3-0.3-0.30.4-0.30.30.10.10.5-0.30.1-0.70.2-0.20.2-0.20.20.3-0.3-0.2
Bone: connectivity density0.91.43.61.9-1.8-1.01.8-1.7-1.91.5-1.7-1.5-1.51.2-1.31.31.0-1.10.50.70.5-0.60.4-0.40.4-0.40.4-0.3-0.21.0
Bone: cortical apparent density0.20.41.40.2-0.50.60.5-0.7-0.6-0.2-0.20.10.10.10.2-0.21.2-1.0-0.60.9-0.60.7-0.70.7-0.70.7-0.7-0.90.70.0
Bone: cortical area0.20.20.70.4-0.4-0.70.6-0.3-0.50.7-0.6-0.6-0.60.8-0.60.60.30.00.1-0.20.6-0.20.6-0.60.6-0.60.60.3-0.40.1
Bone: cortical porosity0.10.10.40.3-0.30.1-0.0-0.3-0.00.1-0.10.20.1-0.30.2-0.20.1-0.50.10.7-0.4-0.2-0.40.4-0.40.4-0.4-0.70.50.6
Bone: cortical porosity0.20.20.60.1-0.30.50.1-0.4-0.1-0.0-0.00.30.2-0.20.3-0.30.5-0.7-0.10.8-0.70.0-0.50.5-0.50.5-0.5-0.70.60.4
Bone: cortical thickness0.30.41.70.6-1.1-0.21.3-1.1-1.10.8-1.0-0.7-0.70.9-0.50.50.5-0.9-0.10.70.1-0.1-0.10.1-0.10.1-0.1-0.50.20.5
Bone: cortical thickness0.20.31.00.2-0.5-0.50.8-0.5-0.50.9-0.6-0.6-0.71.0-0.60.6-0.0-0.20.6-0.10.5-0.60.3-0.30.3-0.30.30.1-0.60.4
Bone: cortical tissue density0.20.41.30.2-0.50.60.4-0.7-0.5-0.2-0.20.10.10.00.3-0.31.2-1.0-0.61.0-0.60.7-0.70.7-0.70.7-0.7-0.90.80.0
Condit. Reinf. active minus inactive responses1.92.18.4-2.92.21.9-2.02.02.1-1.91.91.91.8-1.61.6-1.6-0.81.1-0.0-0.7-0.6-0.0-0.70.7-0.70.7-0.70.20.3-1.3
Condit. Reinf. active-inactive response ratio2.12.26.8-2.62.02.0-1.91.71.9-2.11.92.12.0-1.61.8-1.8-0.10.7-0.4-0.2-1.10.5-1.11.1-1.11.1-1.1-0.20.7-1.5
Condit. Reinf. active responses1.41.86.1-2.51.91.9-1.81.71.8-1.81.71.81.7-1.61.6-1.5-0.90.8-0.4-0.3-0.70.3-0.80.8-0.80.8-0.8-0.10.6-0.7
Condit. Reinf. inactive responses0.10.10.7-0.10.10.1-0.20.20.2-0.20.10.10.2-0.40.2-0.2-0.60.0-0.40.1-0.10.3-0.00.0-0.00.0-0.0-0.10.20.8
Incentive salience index mean2.43.09.5-3.12.42.7-2.32.12.3-2.42.42.32.3-2.02.1-2.1-0.11.0-0.8-0.5-1.00.7-1.01.0-1.01.0-1.0-0.00.7-1.6
Condit. Reinf. lever presses1.11.65.3-2.01.52.3-1.51.31.5-1.71.71.61.6-1.51.6-1.60.90.5-1.2-0.1-1.01.1-0.80.8-0.80.8-0.8-0.20.7-0.7
Condit. Reinf. active minus inactive responses0.30.51.7-0.60.6-0.8-0.60.80.40.10.0-0.0-0.10.2-0.40.4-0.31.01.3-0.90.8-1.30.8-0.80.8-0.80.80.9-0.7-0.2
Condit. Reinf. active-inactive response ratio0.10.20.7-0.60.60.4-0.70.60.4-0.40.50.50.4-0.30.3-0.30.80.40.1-0.3-0.0-0.20.0-0.00.0-0.00.00.20.0-0.8
Condit. Reinf. active responses1.72.56.2-1.31.5-1.6-1.31.91.20.20.3-0.0-0.20.2-0.70.7-1.52.52.2-2.41.9-2.11.8-1.81.8-1.81.82.2-1.9-0.7
Condit. Reinf. inactive responses2.13.27.3-1.11.5-2.2-1.11.91.30.40.2-0.2-0.40.2-0.90.9-2.62.72.3-2.62.2-2.12.1-2.12.1-2.12.12.5-2.2-0.1
Condit. Reinf. lever presses0.60.93.8-0.1-0.1-1.00.40.1-0.60.9-0.9-0.9-0.90.7-1.11.1-0.10.61.9-0.81.2-1.91.0-1.01.0-1.01.01.0-0.60.8
Condit. Reinf. lever reinforcers received1.52.15.3-1.11.3-1.6-1.01.61.00.30.1-0.2-0.30.3-0.80.8-1.42.22.3-2.11.8-2.11.7-1.71.7-1.71.72.0-1.8-0.3
Conditioned reinforcement - actives0.31.23.2-1.41.51.3-1.61.41.4-1.51.71.61.5-1.81.4-1.4-0.10.7-0.4-0.3-0.60.4-0.50.5-0.50.5-0.5-0.10.7-1.2
Conditioned reinforcement - inactives0.10.31.5-0.30.70.2-0.90.70.6-0.50.70.50.5-1.20.4-0.4-1.00.5-0.1-0.30.20.20.3-0.30.3-0.30.30.20.5-0.0
Conditioned locomotion0.40.61.6-1.31.21.0-1.11.10.9-1.11.11.00.9-1.00.8-0.8-0.10.7-0.2-0.5-0.1-0.0-0.10.1-0.10.1-0.10.30.3-1.2
Patch foraging indifference point 0 sec0.41.02.50.8-1.3-0.91.6-1.3-1.61.3-1.4-1.4-1.41.6-1.31.3-0.3-0.60.80.30.5-0.80.4-0.40.4-0.40.40.2-0.50.7
Patch foraging indifference point AUC4.19.815.82.8-2.0-4.02.5-1.3-2.53.7-3.2-3.7-3.83.6-3.93.9-1.51.13.3-2.03.4-3.43.6-3.63.6-3.63.62.7-3.61.5
Delay disc. indifference point, 0s delay0.80.92.5-0.50.6-0.40.00.70.20.4-0.1-0.4-0.41.1-0.60.60.61.30.9-1.51.1-0.91.2-1.21.2-1.21.21.4-1.6-0.8
Delay disc. indifference point, 16s delay2.73.818.81.0-1.62.21.4-2.1-1.4-0.3-0.20.10.30.20.8-0.84.3-2.7-2.22.6-2.42.1-2.32.3-2.32.3-2.3-2.42.10.1
Delay disc. indifference point, 2s delay1.11.27.20.1-0.31.30.2-0.6-0.2-0.60.40.50.70.20.9-0.92.7-1.1-1.71.1-1.22.0-1.31.3-1.31.3-1.3-1.11.0-0.8
Delay disc. indifference point, 24s delay0.81.37.41.4-1.70.11.8-1.8-1.50.9-1.1-1.1-0.81.1-0.50.52.7-1.6-0.71.3-0.70.6-0.70.7-0.70.7-0.7-1.10.50.9
Delay disc. indifference point, 4s delay1.11.28.00.3-0.61.20.6-0.9-0.7-0.4-0.00.30.40.40.6-0.62.8-1.3-1.51.3-1.41.6-1.31.3-1.31.3-1.3-1.20.9-0.0
Delay disc. indifference point, 8s delay0.30.58.4-0.3-0.10.80.1-0.3-0.3-0.30.20.40.30.40.4-0.42.9-0.4-0.90.4-0.70.7-0.50.5-0.50.5-0.5-0.30.3-0.3
Indifference point function ln k2.36.912.5-2.72.03.5-2.41.52.3-3.22.93.23.3-3.23.3-3.31.3-0.6-2.51.3-2.82.8-2.72.7-2.72.7-2.7-1.92.9-1.8
Indifference point function log k2.36.912.5-2.72.03.5-2.41.52.3-3.22.93.23.3-3.23.3-3.31.3-0.6-2.51.3-2.82.8-2.72.7-2.72.7-2.7-1.92.9-1.8
Patch foraging total patch changes 0 sec0.30.92.60.7-1.3-0.81.6-1.3-1.61.3-1.4-1.3-1.31.5-1.21.2-0.4-0.70.80.40.3-0.90.2-0.20.2-0.20.20.1-0.40.8
Patch foraging total patch changes 12 sec5.67.513.02.1-1.9-3.62.5-1.4-2.63.4-2.9-3.4-3.43.3-3.53.5-1.20.73.0-1.53.0-3.02.8-2.82.8-2.82.82.2-2.81.6
Patch foraging total patch changes 18 sec1.43.37.71.0-1.2-2.21.8-0.9-1.72.1-2.1-2.2-2.32.8-2.32.3-0.30.52.0-1.11.8-2.41.8-1.81.8-1.81.81.6-2.40.8
Patch foraging total patch changes 24 sec3.010.217.53.1-2.7-3.93.3-2.0-3.24.2-3.5-4.0-4.14.0-4.14.1-1.00.43.3-1.43.3-3.43.1-3.13.1-3.13.12.2-3.12.0
Patch foraging total patch changes 6 sec3.86.511.72.6-2.7-3.03.1-2.3-3.13.3-3.3-3.4-3.43.4-3.33.3-1.3-0.42.1-0.42.1-2.32.0-2.02.0-2.02.01.2-2.02.7
Patch foraging time to switch 0 sec1.35.08.7-1.71.42.5-2.00.91.9-2.82.42.52.7-2.92.8-2.81.4-0.8-2.61.5-2.42.5-2.52.5-2.52.5-2.5-1.92.3-0.7
Patch foraging water rate 0 sec0.52.05.31.2-1.5-0.92.1-1.3-1.82.1-1.9-1.8-1.92.3-1.81.8-0.3-0.31.5-0.21.0-1.41.0-1.01.0-1.01.00.6-1.11.1
Patch foraging water rate 12 sec0.00.21.7-0.40.00.80.1-0.00.3-0.20.30.20.20.20.3-0.31.3-0.2-0.30.2-0.30.3-0.30.3-0.30.3-0.3-0.20.2-0.4
Patch foraging water rate 18 sec0.20.41.4-1.20.80.2-0.30.90.8-0.10.20.1-0.00.6-0.20.2-0.71.00.7-1.00.7-0.60.7-0.70.7-0.70.70.9-0.8-0.6
Patch foraging water rate 24 sec1.21.64.21.7-1.8-1.12.0-1.6-1.71.9-1.9-1.8-1.71.8-1.51.50.8-0.90.90.40.6-0.70.6-0.60.6-0.60.6-0.1-0.31.1
Patch foraging water rate 6 sec0.20.30.80.1-0.40.90.4-0.5-0.2-0.00.00.20.20.10.4-0.40.9-0.8-0.90.7-0.60.8-0.70.7-0.70.7-0.7-0.70.7-0.1
Seeking ratio, delayed vs. immediate footshock1.01.43.31.7-1.4-1.51.6-1.2-1.51.5-1.5-1.8-1.61.1-1.51.50.1-0.30.8-0.10.8-0.71.0-1.01.0-1.01.00.4-0.41.2
Distance traveled before self-admin0.91.94.91.5-0.8-2.20.7-0.4-0.31.3-1.0-1.5-1.40.9-1.61.6-2.10.51.7-0.71.5-1.81.5-1.51.5-1.51.50.9-1.31.6
Distance traveled after self-admin0.61.03.51.3-0.7-1.90.6-0.3-0.21.2-0.7-1.2-1.10.1-1.21.2-1.90.31.0-0.50.8-1.01.2-1.21.2-1.21.20.6-0.50.8
Extensor digitorum longus weight0.20.71.91.0-1.00.80.9-1.2-0.90.3-0.2-0.2-0.20.30.1-0.11.3-1.4-0.51.2-0.70.3-0.90.9-0.90.9-0.9-1.20.7-0.4
Bone: elastic displacement0.20.20.80.3-0.7-0.30.9-0.7-0.90.3-0.9-0.6-0.60.5-0.50.5-0.3-0.60.20.4-0.0-0.3-0.00.0-0.00.0-0.0-0.20.10.5
Bone: elastic work0.20.30.6-0.2-0.0-0.60.20.1-0.20.3-0.4-0.6-0.50.3-0.60.6-0.60.40.7-0.60.7-0.70.7-0.70.7-0.70.70.7-0.5-0.3
Bone: endosteal estimation0.61.43.9-1.01.8-0.5-1.92.01.9-0.51.40.90.7-0.90.3-0.3-0.72.00.7-1.70.9-0.51.0-1.01.0-1.01.01.3-0.7-1.3
Bone: endosteal perimeter0.51.13.2-1.01.6-0.2-1.81.81.6-0.51.40.70.7-1.10.4-0.4-0.31.70.0-1.50.70.10.9-0.90.9-0.90.91.2-0.3-1.4
Epididymis fat weight0.00.20.5-0.20.40.3-0.30.40.5-0.30.40.20.20.10.1-0.10.70.6-0.4-0.50.20.40.5-0.50.5-0.50.50.4-0.7-0.7
Delta time in closed arm before/after self-admin1.71.65.02.1-2.0-0.72.0-2.1-2.21.5-1.7-1.6-1.51.7-1.21.21.0-1.4-0.31.0-0.10.50.0-0.00.0-0.00.0-0.5-0.31.0
Delta time in open arm before/after self-admin0.81.02.7-1.61.5-0.2-1.61.61.6-1.01.11.10.9-1.50.6-0.6-1.61.3-0.0-0.90.7-0.10.4-0.40.4-0.40.40.70.20.3
Diff in mean of infusions in LGA sessions0.30.51.40.9-0.9-0.40.4-0.8-0.60.3-0.4-0.1-0.1-0.3-0.00.00.7-1.1-0.41.2-0.80.8-0.60.6-0.60.6-0.6-1.01.10.7
Delay discount exponential model param1.62.117.7-0.50.9-1.6-0.81.30.90.30.1-0.2-0.3-0.6-0.70.7-4.21.71.9-1.71.6-1.91.5-1.51.5-1.51.51.5-1.20.1
Extinction: sum of active levers before priming0.10.23.0-0.40.00.40.30.1-0.50.5-0.2-0.1-0.20.4-0.20.21.70.20.5-0.30.1-0.30.3-0.30.3-0.30.30.40.1-0.6
Active lever presses in extinction session 60.40.41.3-0.6-0.01.2-0.0-0.2-0.1-0.40.20.60.5-0.40.5-0.61.1-0.6-0.00.7-0.7-0.4-0.80.8-0.80.8-0.8-0.80.9-0.3
Bone: final force0.40.72.20.30.2-1.0-0.10.40.20.8-0.1-0.4-0.50.5-0.70.7-0.80.91.4-0.91.2-1.51.1-1.11.1-1.11.10.8-0.7-0.7
Bone: final moment0.60.92.70.7-0.2-1.20.30.1-0.21.1-0.5-0.7-0.80.8-1.01.0-0.70.71.6-0.81.3-1.61.2-1.21.2-1.21.20.8-0.8-0.4
Food consumed during 24 hour testing period0.10.20.5-0.30.40.1-0.30.50.4-0.00.2-0.1-0.00.0-0.10.1-0.70.60.7-0.60.1-0.70.4-0.40.4-0.40.40.5-0.4-0.4
Glucose0.40.63.0-1.71.11.1-0.71.00.9-0.91.10.90.8-0.60.8-0.70.00.5-0.1-0.4-0.30.1-0.50.5-0.50.5-0.50.2-0.1-1.7
Heart weight2.03.36.32.0-1.6-1.81.9-1.3-2.22.5-2.1-2.4-2.42.1-2.32.30.90.11.6-0.72.0-1.51.8-1.81.8-1.81.81.2-1.40.9
Delay discount hyperbolic model param1.62.117.0-0.30.7-1.6-0.71.10.80.5-0.1-0.4-0.5-0.5-0.80.8-4.11.62.0-1.61.7-1.91.6-1.61.6-1.61.61.5-1.20.2
Intermittent access intake day 1-15 change0.10.61.60.7-0.50.30.3-0.60.0-0.20.30.20.3-0.50.5-0.5-0.2-1.0-1.20.9-1.11.3-1.11.1-1.11.1-1.1-1.10.3-0.1
Intermittent access intake escalation0.10.30.80.8-0.50.00.4-0.6-0.1-0.00.1-0.00.1-0.20.3-0.3-0.4-0.8-0.90.7-0.80.9-0.80.8-0.80.8-0.8-0.80.10.1
Intermittent access intake escalation 20.10.12.30.30.0-0.6-0.00.10.20.10.1-0.0-0.0-0.2-0.10.1-1.50.0-0.1-0.10.0-0.1-0.00.0-0.00.0-0.00.0-0.4-0.1
Intermitt. access day 1 inactive lever presses0.10.81.7-0.50.21.3-0.4-0.00.2-0.90.80.90.9-1.01.0-1.00.6-0.8-1.21.0-1.10.7-1.11.1-1.11.1-1.1-1.11.30.1
Intermitt. access day 15 inactive lever presses0.21.03.3-1.61.50.7-1.71.61.3-1.11.60.90.9-1.80.6-0.6-1.01.20.1-0.90.2-0.10.4-0.40.4-0.40.40.7-0.1-1.1
Intermitt. access escalation Index0.20.81.61.1-0.7-1.30.9-0.4-0.61.0-0.9-1.2-1.10.6-1.01.0-0.20.30.8-0.61.0-0.31.1-1.11.1-1.11.10.7-0.50.8
Intermittent access day 1 total infusions1.75.116.1-4.03.81.9-3.43.73.3-2.83.02.82.6-2.42.1-2.1-1.12.80.0-2.10.10.10.3-0.30.3-0.30.31.4-0.4-2.4
Intermittent access day 15 total infusions0.30.82.4-1.11.40.2-1.31.41.5-1.01.21.00.9-0.90.7-0.6-1.41.20.0-1.00.2-0.10.3-0.30.3-0.30.30.7-0.9-0.6
Intermittent access terminal intake (last 3 days)1.32.46.7-2.32.50.7-2.32.52.6-1.72.11.91.7-1.71.3-1.3-1.81.90.1-1.50.1-0.10.2-0.20.2-0.20.20.9-0.9-1.6
Intermittent access total infusions1.82.15.8-1.92.30.2-2.02.42.2-1.21.71.31.1-1.30.7-0.7-1.72.30.8-2.00.8-0.71.0-1.01.0-1.01.01.5-1.2-1.3
Intermittent access day 1 locomotion1.62.99.1-3.02.81.6-2.52.72.7-2.22.32.12.0-1.91.6-1.6-0.62.1-0.1-1.50.2-0.10.2-0.20.2-0.20.21.0-0.1-1.7
Intermittent access day 15 total locomotion0.20.72.3-1.20.70.8-0.90.50.6-1.10.81.21.0-1.50.9-0.9-0.8-0.1-0.70.5-0.70.0-0.90.9-0.90.9-0.9-0.60.70.4
Intermittent access total locomotion1.11.43.2-1.81.71.1-1.71.61.8-1.61.61.71.6-1.71.4-1.3-0.50.9-0.6-0.4-0.40.1-0.40.4-0.40.4-0.40.10.2-0.9
Intermittent access standard deviation0.21.02.2-0.70.81.1-1.10.60.9-1.21.21.31.3-1.51.3-1.3-0.5-0.2-0.80.5-1.00.7-1.11.1-1.11.1-1.1-0.80.8-0.4
Left kidney weight0.10.61.51.2-0.2-1.0-0.1-0.1-0.10.9-0.1-0.5-0.70.4-0.70.7-0.10.6-0.1-0.81.10.51.2-1.21.2-1.21.20.7-1.2-0.3
Right kidney weight0.21.24.32.1-1.4-1.31.2-1.2-1.31.7-1.2-1.3-1.41.3-1.31.30.4-0.40.50.11.0-0.40.9-0.90.9-0.90.90.2-0.81.0
Cocaine induced anxiety0.00.10.3-0.00.0-0.1-0.00.2-0.10.30.1-0.3-0.3-0.3-0.40.4-0.60.30.4-0.40.6-0.40.5-0.50.5-0.50.50.5-0.30.1
Post-drug Anxiety0.20.21.6-0.80.61.1-0.40.60.3-0.40.80.40.4-0.60.3-0.30.20.4-0.0-0.3-0.00.0-0.10.1-0.10.1-0.10.30.0-1.3
Baseline Anxiety0.10.11.2-0.80.40.4-0.10.30.1-0.30.10.30.20.30.2-0.2-0.20.2-0.1-0.2-0.3-0.0-0.20.2-0.20.2-0.20.2-0.2-1.1
Tail length0.10.42.10.4-0.00.7-0.5-0.10.2-0.50.50.70.6-0.80.7-0.70.3-0.5-1.40.7-0.51.5-0.50.5-0.50.5-0.5-0.80.80.1
Length with tail0.31.12.6-0.31.0-0.5-1.41.31.10.10.80.10.0-1.2-0.30.3-1.51.60.7-1.51.4-0.61.4-1.41.4-1.41.41.3-0.8-0.1
Length without tail0.84.38.20.40.2-2.5-0.30.90.01.8-0.5-1.6-1.60.3-2.02.0-2.42.22.7-2.52.9-2.72.8-2.82.8-2.82.82.6-2.30.6
Times rat made contact with spout0.80.92.5-1.11.2-0.3-1.21.51.2-0.40.80.40.4-0.80.1-0.1-1.61.50.8-1.30.9-0.70.9-0.90.9-0.90.91.1-0.3-0.9
Lifetime Intake2.22.77.6-2.32.70.5-2.32.72.3-1.41.91.51.3-1.40.8-0.8-1.52.60.9-2.20.9-0.71.1-1.11.1-1.11.11.8-1.3-1.8
Liver weight, left2.03.59.8-2.32.8-0.3-2.63.12.6-1.11.91.21.0-0.90.5-0.5-1.23.10.9-2.81.5-1.01.6-1.61.6-1.61.62.3-1.7-2.4
Liver weight, right0.50.92.0-0.41.0-1.2-1.31.21.0-0.30.80.30.2-0.8-0.00.1-0.91.41.1-1.20.9-0.81.0-1.01.0-1.01.01.1-0.6-1.0
Locomotor activity2.84.39.2-0.80.8-1.8-0.01.2-0.11.0-0.7-1.3-1.41.7-1.91.9-1.82.62.5-2.82.7-2.62.8-2.82.8-2.82.83.0-3.0-1.0
Locomotor testing distance1.74.18.8-0.80.5-1.70.30.9-0.41.0-1.1-1.5-1.62.0-2.02.0-1.22.32.5-2.62.6-2.52.7-2.72.7-2.72.73.0-2.8-0.6
Locomotor testing rearing1.24.37.20.2-0.6-2.01.4-0.1-1.51.6-2.1-2.2-2.22.5-2.52.5-0.81.52.4-2.02.3-2.42.7-2.72.7-2.72.72.5-2.50.7
Locomotion in novel chamber1.31.84.00.1-0.1-1.50.70.1-0.61.2-1.1-1.0-1.21.3-1.41.4-2.01.01.7-1.31.7-1.71.6-1.61.6-1.61.61.5-1.80.1
Locomotion in novel chamber post-restriction0.20.61.20.3-0.0-0.40.10.2-0.20.9-0.0-0.9-0.70.1-0.80.8-0.00.80.6-1.00.8-0.81.1-1.11.1-1.11.11.0-0.9-0.6
Fecal boli incidents, locomotor time 10.30.74.3-0.70.80.5-0.10.90.7-0.20.8-0.2-0.00.5-0.10.11.11.20.4-1.41.00.40.8-0.80.8-0.80.81.2-1.1-2.1
Change in fecal boli incidents, locomotor task2.52.76.01.6-1.9-2.02.0-1.6-2.12.1-2.4-2.1-2.11.6-2.02.0-1.0-0.61.30.21.0-2.21.1-1.11.1-1.11.10.4-0.72.2
Time >=10cm from walls, locomotor time 10.50.61.30.8-0.6-1.10.6-0.4-0.40.8-0.9-0.8-0.90.8-1.01.0-0.90.10.7-0.41.1-0.90.9-0.90.9-0.90.90.4-0.80.4
Bouts of movement, locomotor time 10.10.20.9-0.60.40.9-0.20.40.4-0.10.70.40.4-0.30.4-0.40.60.1-0.1-0.2-0.10.3-0.10.1-0.10.1-0.1-0.10.4-0.8
Total resting periods, locomotor time 10.20.31.0-0.80.71.0-0.30.60.7-0.30.80.60.6-0.40.6-0.60.30.3-0.3-0.3-0.20.4-0.20.2-0.20.2-0.2-0.00.4-0.8
Rest time, locomotor task time 10.30.51.6-0.20.5-0.6-0.10.70.40.40.1-0.1-0.30.3-0.40.4-1.30.90.8-1.10.9-0.70.9-0.90.9-0.90.90.8-1.0-0.7
Distance moved, locomotor task time 10.30.74.21.0-1.1-0.91.0-1.1-1.10.9-1.3-1.2-1.01.0-0.90.90.4-0.60.30.40.3-0.30.3-0.30.3-0.30.30.0-0.02.1
Vertical activity count, locomotor time 10.00.32.20.9-0.7-0.30.2-0.8-0.30.2-0.4-0.3-0.1-0.2-0.00.0-0.0-0.7-0.60.8-0.60.7-0.40.4-0.40.4-0.4-0.60.51.5
Time >=10cm from walls, locomotor time 20.72.14.7-0.20.1-1.30.40.4-0.41.0-0.9-1.1-1.31.4-1.51.5-0.91.51.8-1.72.0-1.52.0-2.02.0-2.02.01.9-2.20.3
Bouts of movement, locomotor time 20.00.10.30.6-0.1-0.00.1-0.1-0.20.4-0.0-0.1-0.20.4-0.20.20.50.10.2-0.10.2-0.10.2-0.20.2-0.20.20.1-0.3-0.5
Total resting periods, locomotor time 20.00.10.40.7-0.2-0.10.1-0.1-0.30.6-0.2-0.2-0.30.5-0.30.30.60.10.2-0.20.3-0.20.4-0.40.4-0.40.40.2-0.3-0.5
Rest time, locomotor task time 20.61.02.51.6-1.1-1.21.3-0.9-1.11.5-1.1-1.1-1.31.3-1.21.20.1-0.20.7-0.21.0-0.90.9-0.90.9-0.90.90.3-0.70.2
Distance moved, locomotor task time 20.20.31.3-1.10.60.6-0.70.50.6-0.80.50.50.7-0.70.6-0.6-0.20.1-0.40.1-0.50.8-0.50.5-0.50.5-0.5-0.10.30.4
Vertical activity count, locomotor time 20.71.73.3-1.31.21.1-1.40.91.5-1.61.41.51.6-1.51.6-1.6-1.10.0-1.40.4-1.51.8-1.31.3-1.31.3-1.3-0.70.6-0.4
Light reinforcement 10.41.74.61.1-0.5-1.90.6-0.2-0.61.7-0.6-1.4-1.40.7-1.51.5-1.00.71.1-1.12.2-1.11.6-1.61.6-1.61.61.2-1.4-0.8
Light reinforcement 20.41.02.51.4-0.8-1.60.9-0.6-0.81.6-0.8-1.4-1.30.5-1.21.2-1.10.10.6-0.51.2-0.51.0-1.01.0-1.01.00.6-0.70.4
Bone: marrow area0.51.23.4-0.91.6-0.4-1.81.81.8-0.41.30.90.7-0.90.3-0.3-0.61.80.6-1.50.9-0.40.9-0.90.9-0.90.91.2-0.6-1.2
Bone: maximum diameter0.20.51.20.5-0.1-1.10.20.1-0.20.8-0.4-0.7-0.60.7-0.70.7-0.10.70.1-0.80.9-0.21.0-1.01.0-1.01.00.8-0.70.2
Bone: maximum force0.40.92.0-0.40.8-0.5-0.61.00.70.40.5-0.0-0.10.2-0.40.4-0.61.31.3-1.41.3-1.31.1-1.11.1-1.11.11.1-0.8-1.4
Bone: maximum moment0.61.12.7-0.00.4-0.8-0.20.70.30.80.0-0.5-0.60.6-0.80.8-0.61.31.6-1.41.6-1.61.4-1.41.4-1.41.41.3-1.1-1.1
Mean time between licks in bursts0.95.310.3-2.32.23.1-2.51.72.4-3.22.82.93.0-2.83.0-3.01.6-0.0-2.30.8-2.32.3-1.91.9-1.91.9-1.9-1.32.2-1.7
Mean num. licks in bursts0.10.31.10.3-0.3-1.00.3-0.2-0.50.6-0.6-0.6-0.60.1-0.70.7-0.30.10.9-0.20.5-1.10.6-0.60.6-0.60.60.4-0.10.7
Cd content in liver0.91.13.7-1.91.70.5-1.41.71.5-0.91.30.90.9-0.50.6-0.6-0.51.50.3-1.30.3-0.60.2-0.20.2-0.20.21.0-0.7-1.8
Co content in liver0.20.20.6-0.60.6-0.3-0.70.80.7-0.30.40.20.1-0.4-0.00.0-0.40.80.6-0.60.5-0.50.5-0.50.5-0.50.50.6-0.3-0.3
Cu content in liver2.73.35.90.10.5-2.3-0.11.00.21.4-0.6-1.2-1.21.2-1.61.6-2.22.12.2-2.32.3-2.12.4-2.42.4-2.42.42.3-2.1-0.7
Fe content in liver1.01.22.60.20.3-1.10.00.50.00.9-0.2-0.9-0.80.9-1.01.0-1.01.30.8-1.61.6-1.01.5-1.51.5-1.51.51.6-1.6-0.5
K content in liver1.31.22.21.2-0.7-1.20.7-0.4-0.81.3-0.9-1.5-1.31.0-1.41.4-0.30.60.7-0.91.3-0.71.5-1.51.5-1.51.51.1-1.1-0.3
Mg content in liver1.71.93.51.4-0.8-1.90.9-0.5-1.11.6-1.3-1.7-1.71.3-1.71.7-0.70.61.2-1.01.7-1.21.7-1.71.7-1.71.71.3-1.30.1
Mn content in liver0.10.10.50.3-0.20.00.1-0.3-0.20.00.0-0.00.0-0.30.1-0.10.7-0.3-0.40.3-0.20.6-0.20.2-0.20.2-0.2-0.30.5-0.1
Na content in liver0.80.92.01.2-0.7-1.40.6-0.4-0.61.1-0.9-1.1-1.10.8-1.21.2-0.60.31.1-0.51.0-1.01.2-1.21.2-1.21.20.7-0.9-0.1
Rb content in liver0.60.72.61.3-1.3-0.61.0-1.3-1.20.4-0.9-0.4-0.40.2-0.20.20.2-1.4-0.41.4-0.60.3-0.60.6-0.60.6-0.6-1.10.81.6
Se content in liver1.21.43.9-0.91.1-0.3-0.71.30.90.30.6-0.2-0.20.4-0.40.4-0.81.90.9-2.01.4-1.01.4-1.41.4-1.41.41.7-1.6-1.8
Sr content in liver0.20.20.50.2-0.4-0.40.5-0.4-0.40.4-0.6-0.5-0.50.7-0.50.50.2-0.10.6-0.00.2-0.30.1-0.10.1-0.10.10.2-0.40.7
Zn content in liver0.30.40.8-0.30.3-0.6-0.10.40.10.5-0.1-0.4-0.40.5-0.50.5-0.30.80.7-0.90.8-0.70.8-0.80.8-0.80.80.9-0.9-0.7
Bone: minimum diameter0.51.02.6-1.51.60.5-1.61.61.6-1.11.41.21.2-1.10.9-0.9-0.21.2-0.3-0.80.10.20.1-0.10.1-0.10.10.50.2-1.5
Time in familiar zone, hab. session 10.10.10.20.4-0.1-0.00.0-0.2-0.1-0.0-0.00.20.1-0.10.2-0.2-0.0-0.30.00.3-0.20.1-0.40.4-0.40.4-0.4-0.40.2-0.1
Time in novel zone, hab. session 11.21.44.11.9-1.9-1.11.7-1.8-1.71.4-1.6-1.3-1.31.2-1.11.00.2-1.40.01.1-0.0-0.2-0.00.0-0.00.0-0.0-0.70.12.0
Total zone transitions, hab. session 10.30.41.20.5-1.00.41.0-1.1-1.10.4-0.7-0.7-0.50.4-0.30.30.4-1.00.10.8-0.20.1-0.40.4-0.40.4-0.4-0.50.21.1
Total locomotion distance, hab. session 10.81.23.51.6-1.70.51.6-1.9-1.50.6-0.9-0.9-0.80.9-0.40.41.2-1.7-0.61.4-0.70.8-0.70.7-0.70.7-0.7-1.10.21.2
Locomotion velocity, hab. session 10.50.71.91.1-1.20.81.0-1.4-1.10.2-0.5-0.6-0.40.4-0.10.11.2-1.3-0.71.2-0.60.8-0.60.6-0.60.6-0.6-0.90.30.9
Time in familiar zone, hab. session 20.20.20.9-0.30.60.1-0.90.70.8-0.50.70.50.5-0.90.4-0.4-0.20.5-0.0-0.30.00.2-0.00.0-0.00.0-0.00.10.2-0.3
Time in novel zone, hab. session 22.93.26.42.1-2.1-1.92.5-1.9-2.42.5-2.5-2.3-2.42.5-2.22.2-0.6-0.71.60.11.4-1.81.1-1.11.1-1.11.10.4-1.11.4
Total zone transitions, hab. session 22.02.65.60.1-0.1-1.50.50.3-0.61.5-1.0-1.6-1.51.2-1.81.8-1.11.42.4-1.72.2-2.12.1-2.12.1-2.12.12.0-1.90.4
Total locomotion distance, hab. session 21.01.32.30.9-0.7-1.11.0-0.5-0.91.3-1.0-1.5-1.41.4-1.51.5-0.50.51.3-0.91.5-1.01.3-1.31.3-1.31.31.1-1.50.6
Locomotion velocity, hab. session 20.60.71.50.6-0.4-0.70.7-0.3-0.60.9-0.7-1.2-1.01.0-1.11.1-0.20.51.0-0.71.1-0.61.0-1.01.0-1.01.00.9-1.20.5
Novel to familiar place preference ratio3.44.512.93.6-3.5-1.33.4-3.5-3.32.4-2.9-2.5-2.42.6-2.02.01.2-2.5-0.11.9-0.10.00.0-0.00.0-0.00.0-1.2-0.12.3
Novelty place preference4.25.416.54.1-3.8-1.63.7-3.8-3.72.8-3.2-2.8-2.72.8-2.22.21.4-2.7-0.02.00.1-0.00.2-0.20.2-0.20.2-1.2-0.12.4
Time in novel zone, NPP test5.46.619.54.4-4.1-2.04.0-4.0-4.03.3-3.6-3.2-3.23.2-2.72.71.4-2.60.41.90.4-0.50.5-0.50.5-0.50.5-1.0-0.32.6
Total zone transitions, NPP test1.11.64.1-1.10.9-0.7-0.41.20.50.40.1-0.6-0.60.5-0.90.9-1.21.81.5-2.01.5-1.41.6-1.61.6-1.61.62.0-1.8-0.8
Total locomotion distance, NPP test0.40.62.0-0.70.6-0.2-0.10.70.40.10.1-0.5-0.40.7-0.50.5-0.81.10.8-1.30.9-0.60.9-0.90.9-0.90.91.3-1.4-0.6
Locomotion velocity, NPP test0.40.61.8-1.00.9-0.1-0.41.00.7-0.20.4-0.2-0.10.4-0.20.3-0.91.30.5-1.30.7-0.40.8-0.80.8-0.80.81.3-1.3-1.0
Intraocular pressure0.10.10.4-0.40.40.2-0.40.4-0.0-0.10.40.10.2-0.50.2-0.2-0.20.40.2-0.40.6-0.00.1-0.10.1-0.10.10.30.3-0.6
Delta distance traveled before/after self-admin0.00.00.3-0.1-0.0-0.3-0.10.10.00.30.1-0.1-0.0-0.5-0.10.1-0.50.1-0.3-0.20.00.50.2-0.20.2-0.20.20.10.0-0.3
Delta ambulatory time before/after self-admin0.30.61.40.1-0.40.40.2-0.5-0.2-0.10.20.20.4-0.70.5-0.50.6-1.0-1.01.0-1.21.1-1.11.1-1.11.1-1.1-1.01.10.1
Parametrial fat weight1.22.96.1-1.51.42.3-1.91.21.8-2.12.12.22.1-2.52.1-2.1-0.1-0.2-1.40.7-1.61.6-1.71.7-1.71.7-1.7-1.11.80.1
Pavlov. Cond. lever latency1.92.45.72.4-2.2-2.32.1-2.0-2.01.9-2.2-1.9-2.01.8-1.81.8-0.3-1.11.10.70.7-1.20.7-0.70.7-0.70.7-0.2-0.51.6
Pavlov. Cond. magazine entry latency1.51.93.7-1.71.31.6-1.61.11.6-1.81.61.91.8-1.71.7-1.70.7-0.0-1.10.5-1.50.9-1.31.3-1.31.3-1.3-0.81.1-0.8
Pavlov. Cond. change in total contacts2.32.56.3-2.11.72.5-1.71.41.6-2.01.92.02.0-1.82.0-2.00.40.2-1.50.2-1.41.4-1.41.4-1.41.4-1.4-0.61.0-1.0
Pavlov. Cond. index score1.82.34.7-2.22.02.0-2.01.82.0-1.92.12.02.0-1.71.8-1.80.50.8-1.2-0.3-1.01.2-0.90.9-0.90.9-0.9-0.10.5-1.4
Pavlov. Cond. latency score2.12.65.9-2.42.32.1-2.22.02.2-2.02.32.12.1-1.91.9-1.90.41.0-1.2-0.5-0.91.2-0.80.8-0.80.8-0.80.00.5-1.6
Pavlov. Cond. lever contacts2.63.27.7-2.52.32.8-2.32.02.2-2.32.52.32.3-2.12.2-2.20.60.9-1.6-0.4-1.11.5-1.01.0-1.01.0-1.0-0.10.8-1.6
Pavlov. Cond. magazine entry number1.51.93.71.5-1.2-1.61.4-0.9-1.51.7-1.5-1.9-1.81.5-1.81.8-0.80.21.2-0.71.6-1.11.4-1.41.4-1.41.41.0-1.10.6
Pavlov. Cond. intertrial magazine entries1.01.23.6-0.70.9-0.2-0.41.10.40.30.2-0.4-0.40.6-0.60.6-1.61.70.9-1.91.5-0.81.4-1.41.4-1.41.41.8-1.6-0.8
Pavlov. Cond. lever-magazine prob. diff.2.12.65.0-2.12.02.2-2.11.72.1-2.12.22.22.1-1.92.0-2.00.70.6-1.6-0.1-1.31.5-1.11.1-1.11.1-1.1-0.40.7-1.5
Pavlov. Cond. response bias1.31.63.3-1.61.41.7-1.61.11.5-1.61.61.81.7-1.51.6-1.60.50.2-1.00.2-1.30.9-1.11.1-1.11.1-1.1-0.60.8-0.9
Pavlov. Cond. lever latency1.01.34.0-0.60.91.0-1.00.61.2-1.41.51.41.4-1.11.5-1.5-0.2-0.1-2.00.4-1.21.9-1.11.1-1.11.1-1.1-0.70.6-1.4
Pavlov. Cond. magazine entry latency0.10.20.4-0.30.3-0.1-0.30.50.20.1-0.0-0.1-0.1-0.2-0.20.2-0.40.60.6-0.60.5-0.60.6-0.60.6-0.60.60.6-0.10.0
Pavlov. Cond. change in total contacts0.61.43.6-0.40.5-1.3-0.40.90.30.6-0.3-0.5-0.60.3-0.90.9-1.01.51.9-1.51.6-1.81.5-1.51.5-1.51.51.5-1.10.5
Pavlov. Cond. index score0.30.52.0-0.1-0.0-0.50.10.2-0.20.6-0.6-0.6-0.60.3-0.80.8-0.10.61.4-0.60.9-1.30.9-0.90.9-0.90.90.8-0.40.6
Pavlov. Cond. latency score0.20.31.6-0.30.1-0.3-0.00.3-0.10.4-0.4-0.4-0.40.1-0.50.5-0.10.51.3-0.60.7-1.10.7-0.70.7-0.70.70.7-0.20.4
Pavlov. Cond. lever contacts0.91.33.40.7-1.0-0.91.2-0.8-1.41.4-1.6-1.4-1.41.1-1.51.50.4-0.11.8-0.21.1-1.81.0-1.01.0-1.01.00.6-0.51.4
Pavlov. Cond. magazine entry number0.20.20.5-0.1-0.00.50.1-0.20.0-0.40.40.40.4-0.10.5-0.50.5-0.4-0.70.4-0.50.7-0.70.7-0.70.7-0.7-0.50.3-0.6
Pavlov. Cond. intertrial magazine entries0.20.41.40.00.0-0.70.20.1-0.10.6-0.3-0.4-0.50.9-0.60.6-0.20.61.0-0.70.7-1.00.7-0.70.7-0.70.70.7-1.2-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.62.1-0.20.1-0.50.00.3-0.10.6-0.5-0.5-0.60.3-0.80.8-0.10.71.4-0.80.9-1.41.0-1.01.0-1.01.00.9-0.50.4
Pavlov. Cond. response bias0.60.82.50.4-0.5-0.90.6-0.3-0.71.0-1.0-1.0-1.00.7-1.11.1-0.10.31.6-0.41.0-1.60.9-0.90.9-0.90.90.7-0.51.2
Time in closed arm before self-admin0.81.52.6-0.70.31.5-0.80.10.7-1.40.81.41.4-1.11.4-1.40.4-0.9-1.11.3-1.60.8-1.51.5-1.51.5-1.5-1.51.6-0.1
Time in closed arm after self-admin0.50.61.61.0-1.00.31.0-1.2-1.30.4-0.7-0.5-0.40.8-0.10.11.3-1.2-0.51.0-0.70.5-0.60.6-0.60.6-0.6-0.80.50.2
Time in open arm before self-admin0.81.04.12.0-1.5-1.01.4-1.4-1.31.6-1.2-1.4-1.31.0-1.11.10.7-0.80.60.50.2-0.60.3-0.30.3-0.30.3-0.2-0.30.9
Time in open arm after self-admin1.01.13.50.6-0.4-1.90.4-0.0-0.21.2-0.8-0.9-1.10.4-1.21.2-1.70.71.0-0.91.4-1.01.3-1.31.3-1.31.30.9-0.81.2
Bone: periosteal estimation0.20.51.4-0.71.0-0.3-1.11.21.2-0.20.80.60.5-0.50.3-0.2-0.11.10.2-0.90.6-0.10.6-0.60.6-0.60.60.7-0.3-0.8
Bone: periosteal perimeter0.20.40.90.10.3-0.6-0.40.60.30.40.2-0.3-0.2-0.0-0.30.30.30.90.2-0.90.9-0.10.9-0.90.9-0.90.90.8-0.3-0.6
Bone: post-yield work0.61.04.3-1.01.60.5-1.51.61.4-0.51.30.90.8-0.50.6-0.6-0.21.50.4-1.30.7-0.50.5-0.50.5-0.50.50.9-0.6-2.1
Progressive ratio test 1 active lever presses1.01.74.6-1.21.6-0.1-1.21.81.3-0.30.90.40.2-0.5-0.10.1-1.02.21.7-2.01.4-1.41.5-1.51.5-1.51.51.8-1.4-1.5
Progressive ratio test 1 breakpoint1.01.74.7-1.31.6-0.1-1.21.81.3-0.30.90.40.3-0.4-0.10.1-1.02.21.7-2.01.4-1.41.4-1.41.4-1.41.41.8-1.4-1.5
Progressive ratio test 1 inactive lever presses0.41.02.4-1.51.41.5-1.41.31.1-1.41.61.21.3-1.41.1-1.10.10.7-0.6-0.4-0.40.5-0.30.3-0.30.3-0.30.20.5-1.4
Progressive ratio test 2 active lever presses1.82.66.3-1.41.6-0.9-1.31.91.2-0.10.60.2-0.0-0.1-0.50.5-2.32.51.6-2.42.0-1.82.0-2.02.0-2.02.02.2-2.1-1.1
Progressive ratio test 2 breakpoint1.92.55.9-1.31.6-0.9-1.31.91.2-0.10.60.2-0.1-0.2-0.50.5-2.42.41.6-2.32.0-1.81.9-1.91.9-1.91.92.2-2.0-1.0
Progressive ratio test 2 inactive lever presses0.20.81.9-1.31.40.6-1.41.40.8-0.81.10.80.7-1.10.4-0.4-0.71.30.3-1.10.6-0.30.6-0.60.6-0.60.60.9-0.5-0.9
Incentive Sensitization - Responses0.51.45.2-1.81.8-0.0-1.71.91.6-1.01.31.10.9-1.00.6-0.6-2.31.70.2-1.40.7-0.40.6-0.60.6-0.60.61.1-0.8-0.9
Incentive Sensitization - Breakpoint0.61.45.3-1.81.8-0.0-1.71.91.6-1.01.31.10.9-1.10.6-0.6-2.31.60.2-1.30.6-0.40.6-0.60.6-0.60.61.0-0.7-0.8
Sum of active levers in priming session hrs 5-60.40.41.0-0.50.50.6-0.70.40.5-0.50.70.80.8-1.00.8-0.80.6-0.1-0.30.3-0.70.3-0.50.5-0.50.5-0.5-0.50.9-0.5
Progressive ratio0.51.63.61.0-1.5-1.21.7-1.3-1.71.5-1.9-1.8-1.81.8-1.71.7-0.9-0.30.8-0.20.6-0.80.9-0.90.9-0.90.90.6-1.21.3
Food seeking constrained by brief footshock2.32.96.20.2-0.61.30.1-1.0-0.5-1.00.31.01.1-0.91.4-1.42.5-2.0-2.12.2-2.41.9-2.32.3-2.32.3-2.3-2.22.3-0.2
Seeking ratio, punishment vs. effort1.22.64.8-0.30.51.6-1.10.20.8-1.51.51.71.8-2.02.0-2.02.2-1.1-1.71.5-1.71.7-1.91.9-1.91.9-1.9-1.82.2-1.0
Retroperitoneal fat weight0.00.20.7-0.30.5-0.1-0.50.50.5-0.30.30.30.20.10.1-0.1-0.70.60.4-0.50.30.00.3-0.30.3-0.30.30.4-0.80.5
Reaction time number correct0.20.61.7-1.11.2-0.1-0.91.31.1-0.50.70.60.4-0.00.2-0.2-1.01.30.4-1.20.6-0.10.6-0.60.6-0.60.60.9-0.6-0.9
Reaction time mean minus median0.64.07.1-1.21.02.6-1.40.51.5-2.32.02.22.3-1.92.4-2.41.5-1.0-2.71.5-2.22.3-2.42.4-2.42.4-2.4-1.91.7-0.9
Reaction time mean minus median AUC0.31.83.6-0.50.31.8-0.5-0.00.6-1.31.11.31.4-1.01.5-1.51.8-1.0-1.91.3-1.41.6-1.71.7-1.71.7-1.7-1.51.2-0.6
Reaction time num false alarms1.01.72.80.4-0.7-0.91.3-0.5-1.31.4-1.4-1.5-1.61.7-1.71.7-0.60.51.6-0.91.6-1.51.4-1.41.4-1.41.41.3-1.6-0.1
Reaction time num false alarms AUC0.51.22.4-0.1-0.3-0.60.9-0.2-1.01.0-1.1-1.1-1.21.5-1.31.3-0.40.71.5-1.01.5-1.41.2-1.21.2-1.21.21.4-1.5-0.4
Reaction time trials correct on left0.20.61.7-1.11.2-0.1-0.91.31.1-0.50.70.60.4-0.00.2-0.2-1.01.30.4-1.20.6-0.10.6-0.60.6-0.60.60.9-0.6-0.9
Reaction time trials on left0.20.61.9-1.21.30.0-1.01.41.2-0.60.80.80.6-0.10.3-0.3-0.91.30.3-1.20.50.00.5-0.50.5-0.50.50.9-0.5-1.0
Reaction time mean2.45.49.2-2.32.02.9-2.41.62.5-3.02.92.82.9-3.02.9-2.91.5-0.2-2.40.9-2.22.2-2.22.2-2.22.2-2.2-1.41.9-1.8
Reaction time mean AUC2.15.28.8-2.21.83.0-2.21.42.3-2.92.82.62.8-2.82.8-2.81.7-0.3-2.40.9-2.32.3-2.32.3-2.32.3-2.3-1.51.9-1.8
Median of all reaction times3.14.88.5-2.21.92.8-2.31.52.4-2.92.82.62.7-2.92.7-2.71.6-0.1-2.20.8-2.12.1-2.12.1-2.12.1-2.1-1.31.8-1.9
Reaction time omissions3.15.111.9-2.51.83.4-2.01.32.0-2.82.52.72.7-2.12.8-2.81.7-0.4-2.61.0-2.42.1-2.32.3-2.32.3-2.3-1.41.8-2.0
Reaction time false alarm rate0.91.22.70.8-1.1-0.61.5-1.1-1.71.3-1.6-1.5-1.51.6-1.41.40.0-0.11.2-0.21.0-1.20.8-0.80.8-0.80.80.7-1.10.3
Reaction time premature initiation rate0.20.42.20.8-0.3-1.00.1-0.2-0.30.7-0.6-0.4-0.60.3-0.70.7-0.80.20.2-0.20.7-0.60.6-0.60.6-0.60.60.3-0.41.5
Reaction time premature initiations0.20.51.0-0.00.4-1.0-0.40.60.30.4-0.2-0.1-0.30.2-0.50.5-0.91.00.4-0.91.0-0.70.9-0.90.9-0.90.90.9-0.70.9
Std. dev. reaction times1.34.26.5-1.41.12.5-1.50.61.6-2.42.12.32.4-2.12.5-2.51.6-1.0-2.51.5-2.32.0-2.52.5-2.52.5-2.5-1.91.8-1.1
Reaction time trials completed0.20.61.9-1.21.30.0-1.01.41.2-0.60.80.80.6-0.10.3-0.3-0.91.30.3-1.20.50.00.5-0.50.5-0.50.50.9-0.5-1.0
Reaction time trials AUC0.20.61.7-1.31.30.1-0.91.31.1-0.70.80.80.6-0.10.4-0.4-0.81.20.2-1.10.40.00.4-0.40.4-0.40.40.8-0.5-1.1
Run reversals in cocaine runway, females0.50.51.40.6-0.80.20.5-0.9-0.5-0.1-0.60.0-0.00.10.1-0.1-0.7-1.2-0.21.2-1.0-0.0-0.90.9-0.90.9-0.9-1.10.71.0
Run reversals in cocaine runway, males3.03.36.2-2.01.62.4-1.91.32.0-2.32.32.42.3-2.52.3-2.31.1-0.1-1.30.7-1.40.6-1.81.8-1.81.8-1.8-1.21.6-1.5
Latency to leave start box in cocaine runway1.01.42.9-0.70.51.7-1.10.30.7-1.50.91.41.4-1.41.4-1.4-0.1-0.6-1.51.1-1.31.0-1.31.3-1.31.3-1.3-1.21.60.4
Latency to leave start box in cocaine runway, F0.20.21.6-0.40.30.6-0.70.30.4-0.60.30.60.5-0.60.4-0.4-1.30.1-0.60.1-0.30.1-0.20.2-0.20.2-0.2-0.20.30.5
Latency to leave start box in cocaine runway, M3.53.36.0-0.90.62.4-1.20.20.9-2.11.52.02.0-2.02.2-2.21.4-1.1-2.31.7-2.11.9-2.12.1-2.12.1-2.1-1.92.4-0.3
Std. dev. time between licks in bursts0.20.41.7-1.31.10.4-0.91.00.8-1.10.70.80.9-0.60.8-0.80.20.6-0.3-0.4-0.20.3-0.20.2-0.20.2-0.20.20.2-0.0
Total sessions with >9 infusions2.12.67.2-2.72.71.5-2.42.62.3-1.82.21.91.8-1.81.4-1.4-0.22.10.4-1.60.00.20.3-0.30.3-0.30.31.1-0.1-2.2
Short access day 1 total inactive lever presses0.30.71.8-1.11.01.4-0.80.90.9-1.31.20.91.0-0.51.0-1.00.50.5-1.1-0.3-0.30.9-0.20.2-0.20.2-0.20.10.1-1.3
Short access day 10 total inactive lever presses0.53.49.21.6-1.90.91.4-2.3-1.50.2-0.7-0.00.1-0.10.6-0.61.4-3.0-2.33.0-2.31.6-2.32.3-2.32.3-2.3-2.82.11.4
Short access day 1 total infusions1.83.59.3-3.03.11.7-2.83.02.5-2.12.62.11.9-1.91.5-1.50.02.50.3-2.00.30.20.6-0.60.6-0.60.61.5-0.5-3.0
Short access day 10 total infusions1.21.95.5-2.32.31.0-2.22.32.2-1.61.81.61.5-1.61.1-1.1-0.51.80.2-1.40.1-0.20.4-0.40.4-0.40.40.9-0.3-1.5
Short access total infusions3.04.211.7-3.43.41.5-3.03.42.9-2.12.62.21.9-1.91.4-1.4-0.73.00.7-2.40.6-0.30.8-0.80.8-0.80.81.9-1.0-2.8
Short access day 1 locomotion0.40.61.5-0.30.5-0.3-0.40.60.00.10.2-0.1-0.2-0.4-0.40.40.11.11.2-1.01.0-1.01.2-1.21.2-1.21.21.1-0.5-0.9
Short access day 10 total locomotion0.72.74.4-0.90.61.8-0.90.21.0-1.81.31.91.8-1.41.9-1.91.4-1.1-2.01.6-2.11.4-2.12.1-2.12.1-2.1-1.82.0-0.6
Short access total locomotion0.40.61.7-1.11.30.4-1.21.31.1-0.80.90.90.7-0.70.5-0.50.41.10.4-0.90.3-0.40.4-0.40.4-0.40.40.7-0.2-1.2
One hour access (0.3 mA shock)1.01.27.9-0.61.0-1.0-0.81.30.90.10.50.10.0-0.6-0.30.3-2.81.51.1-1.51.1-0.81.2-1.21.2-1.21.21.3-0.9-0.3
Compulsive drug intake0.10.20.8-0.4-0.10.60.4-0.2-0.3-0.1-0.10.10.30.20.3-0.3-0.1-0.5-0.40.4-0.60.9-0.60.6-0.60.6-0.6-0.40.50.1
One hour access (shock baseline)0.41.13.5-0.71.2-0.8-1.21.41.1-0.20.70.30.2-0.9-0.10.1-1.91.61.1-1.51.0-1.11.1-1.11.1-1.11.11.3-0.9-0.6
Social response proportion1.21.54.1-2.01.22.0-0.80.91.1-1.41.61.31.5-0.71.5-1.50.90.1-0.90.2-0.91.0-1.21.2-1.21.2-1.2-0.40.5-2.0
Social responses0.30.31.30.5-0.80.31.1-0.8-0.70.6-0.7-0.5-0.41.1-0.30.31.0-0.7-0.30.5-0.10.5-0.30.3-0.30.3-0.3-0.4-0.1-0.2
Social time1.42.26.4-2.32.41.2-2.22.32.2-1.62.21.51.6-1.81.4-1.3-1.01.8-0.3-1.40.40.20.1-0.10.1-0.10.10.9-0.3-2.5
Soleus weight3.911.333.85.8-5.50.35.1-5.8-4.93.1-3.4-2.8-2.62.7-1.61.54.2-5.2-1.94.3-1.51.9-1.61.6-1.61.6-1.6-3.51.63.4
Bone: stiffness0.40.72.5-0.30.9-0.2-0.81.11.00.20.80.20.10.1-0.10.1-0.11.30.8-1.31.1-0.70.9-0.90.9-0.90.91.0-0.9-1.6
Tibialis anterior weight0.10.41.21.1-1.00.21.0-1.0-1.00.9-0.6-0.9-0.80.8-0.70.70.8-0.60.20.30.2-0.50.0-0.00.0-0.00.0-0.2-0.4-0.3
Time to tail flick, vehicle, before self-admin0.81.03.9-2.01.51.5-1.31.41.6-1.41.51.31.2-0.51.0-1.00.00.80.0-0.5-0.4-0.1-0.30.3-0.30.3-0.30.2-0.3-1.0
Time to tail flick, vehicle, after self-admin0.40.83.4-1.71.30.3-0.91.20.8-0.80.50.60.50.10.2-0.2-1.81.20.4-1.00.6-0.60.6-0.60.6-0.60.61.1-1.0-0.8
Time to tail flick, test, before self-admin2.02.35.81.6-1.70.41.5-2.0-1.30.3-0.8-0.2-0.20.40.3-0.32.2-2.4-1.72.3-1.71.4-1.71.7-1.71.7-1.7-2.11.51.5
Time to tail flick, test, after self-admin3.03.28.22.4-2.6-0.62.3-2.9-2.51.0-1.9-1.2-1.01.4-0.50.52.0-2.8-1.22.5-0.90.6-1.51.5-1.51.5-1.5-2.01.12.7
Delta time to tail flick, vehicle, before/after SA0.10.11.4-0.30.2-0.2-0.10.1-0.1-0.2-0.1-0.00.0-0.40.0-0.0-1.20.1-0.2-0.10.10.20.1-0.10.1-0.10.10.20.10.5
Delta time to tail flick, test, before/after SA0.60.82.30.9-1.0-1.11.1-0.9-1.40.9-1.3-1.1-1.11.5-1.01.0-0.2-0.40.40.10.7-0.60.5-0.50.5-0.50.50.2-0.90.8
Tibia length1.74.713.6-2.22.8-1.0-2.23.22.1-0.31.30.60.40.2-0.20.2-2.43.71.8-3.52.5-1.92.3-2.32.3-2.32.33.1-2.3-2.4
Ambulatory time before self-admin0.92.87.41.2-0.2-2.50.30.30.11.3-0.8-1.3-1.40.6-1.71.7-2.71.32.1-1.52.1-2.22.2-2.22.2-2.22.21.6-1.61.0
Ambulatory time after self-admin0.30.53.70.5-0.2-1.30.00.10.30.6-0.2-0.6-0.4-0.5-0.60.6-1.90.30.9-0.30.4-0.90.6-0.60.6-0.60.60.3-0.10.8
Bone: tissue strength0.20.20.9-0.20.3-0.3-0.30.40.2-0.00.1-0.1-0.1-0.1-0.20.2-0.50.50.7-0.50.5-1.00.4-0.40.4-0.40.40.5-0.3-0.7
Total heroin consumption0.80.92.61.6-1.5-0.71.1-1.5-1.11.0-1.1-0.7-0.80.4-0.60.61.4-1.30.21.3-0.4-0.3-0.30.3-0.30.3-0.3-1.10.81.3
Bone: trabecular number1.63.09.33.1-3.0-0.62.7-3.1-2.81.8-2.2-1.7-1.71.3-1.21.21.9-2.5-0.62.1-0.40.4-0.40.4-0.40.4-0.4-1.50.51.8
Bone: trabecular spacing2.23.29.8-2.52.4-1.2-1.82.71.9-0.41.00.30.4-0.1-0.20.2-2.03.11.4-2.91.7-1.41.7-1.71.7-1.71.72.7-1.9-1.4
Bone: trabecular thickness2.12.96.10.1-0.32.5-0.1-0.70.2-1.31.01.41.4-1.21.7-1.72.2-1.8-2.22.1-2.32.2-2.12.1-2.12.1-2.1-2.22.1-0.4
Bone: trabecular tissue density1.83.110.2-2.51.83.2-1.81.41.9-2.32.22.02.1-1.72.1-2.11.00.3-1.40.2-1.51.5-1.41.4-1.41.4-1.4-0.61.1-2.1
Water consumed over 24 hours0.61.36.20.10.0-1.40.10.4-0.11.0-0.7-0.7-0.80.5-1.11.1-2.50.92.0-1.01.4-1.91.2-1.21.2-1.21.21.0-0.9-0.0
Number of responses in last shaping day0.50.72.50.10.0-1.10.20.2-0.10.7-0.4-0.5-0.70.3-0.80.8-1.60.71.1-0.80.9-1.11.0-1.01.0-1.01.00.8-1.20.4