Hub : Genes

Pld1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Pld1 0.33 0.12 0.0e+00 0.26 0.27 0.28 0.27 1.8e-28 5.1e-30 3.2e-31 3.6e-30
2 NAcc gene expression Pld1 0.03 0.02 4.4e-04 0.02 0.02 0.01 0.02 1.8e-03 7.5e-04 6.5e-03 2.6e-03
3 Adipose mRNA stability Pld1 0.04 0.03 3.9e-03 0.02 0.02 0.01 0.01 6.0e-03 4.4e-03 3.4e-02 1.1e-02
4 Brain alternative TSS NM_001399082.1 0.03 0.02 4.1e-03 0.01 0.02 0.01 0.01 2.3e-02 7.9e-03 7.3e-02 2.4e-02
5 Brain alternative TSS XM_006232206.4 0.03 0.02 3.7e-03 0.01 0.02 0 0.01 2.1e-02 6.8e-03 1.0e-01 2.2e-02
6 Adipose alternative TSS NM_001399082.1 0.09 0.06 3.6e-08 0.05 0.06 0.06 0.05 2.4e-06 8.7e-07 7.1e-07 1.5e-06
7 Adipose alternative TSS XM_006232206.4 0.09 0.06 2.5e-08 0.05 0.06 0.06 0.05 2.1e-06 7.4e-07 6.2e-07 1.4e-06
8 NAcc intron excision ratio chr2_110979168_110986670 0.05 0.05 1.2e-03 0.03 0.02 0.03 0.02 5.6e-04 3.1e-03 5.6e-04 2.6e-03
9 Adipose intron excision ratio chr2_110849487_110862003 0.13 0.07 4.4e-13 0.1 0.09 0.09 0.09 2.2e-11 1.3e-10 5.1e-10 3.5e-10
10 Adipose intron excision ratio chr2_110849831_110862003 0.12 0.07 4.5e-12 0.09 0.09 0.09 0.09 1.9e-10 3.7e-10 4.9e-10 9.8e-10
11 Adipose intron excision ratio chr2_110979168_110986670 0.05 0.04 5.1e-05 0.04 0.03 0.03 0.03 8.1e-05 1.4e-04 7.9e-04 1.4e-04
12 OFC mRNA stability Pld1 0.26 0.15 1.8e-03 0.07 0.05 0.02 0.07 1.0e-02 2.9e-02 1.3e-01 1.0e-02
13 Brain isoform ratio NM_030992.3 0.04 0.03 3.0e-03 0.03 0.02 0.02 0.03 3.9e-04 3.4e-03 7.0e-03 1.9e-03
14 Adipose intron excision ratio chr2_110980055_110986670 0.02 0.02 9.6e-03 0.01 0 0.01 0 2.2e-02 2.4e-01 5.7e-02 9.0e-02
15 Brain isoform ratio XM_006232206.4 0.03 0.02 1.8e-03 0.03 0.02 0 0.03 9.1e-04 6.6e-03 1.0e-01 1.6e-03
16 Adipose isoform ratio XM_006232206.4 0.08 0.06 1.2e-07 0.05 0.05 0.05 0.05 6.8e-06 2.0e-06 2.9e-06 5.3e-06
17 Brain mRNA stability Pld1 0.16 0.09 3.8e-11 0.09 0.11 0.11 0.11 1.9e-08 1.0e-10 2.5e-10 2.0e-10
18 PL isoform ratio NM_001399082.1 0.04 0.03 6.7e-04 0.01 0.03 0.03 0.03 4.2e-02 3.0e-04 2.8e-04 5.9e-04
19 PL isoform ratio NM_030992.3 0.03 0.02 5.4e-03 0.01 0.01 0.01 0 6.7e-02 8.7e-03 2.2e-02 7.7e-02
20 PL mRNA stability Pld1 0.09 0.04 2.7e-08 0.06 0.08 0.07 0.07 5.9e-07 4.4e-09 5.1e-08 2.9e-08
21 Brain gene expression Pld1 0.05 0.03 1.8e-03 0.01 0.01 0.02 0.01 1.7e-02 1.4e-02 2.5e-03 3.2e-02
22 BLA mRNA stability Pld1 0.26 0.12 1.6e-07 0.1 0.12 0.1 0.1 3.6e-06 8.4e-07 4.6e-06 5.4e-06
23 Adipose gene expression Pld1 0.33 0.16 0.0e+00 0.19 0.2 0.19 0.19 2.8e-20 3.3e-21 6.0e-21 4.2e-21
24 Adipose isoform ratio NM_030992.3 0.03 0.02 6.6e-03 0.02 0.01 0.01 0.01 6.6e-03 2.3e-02 8.8e-03 1.6e-02
25 PL gene expression Pld1 0.05 0.04 7.7e-05 0.02 0.02 0.04 0.01 2.3e-03 2.1e-03 3.4e-05 8.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.81.44.0-0.9-1.8-1.9-0.20.2-0.50.5-1.6-0.60.6-0.6-0.5-0.90.81.3-1.00.92.01.51.61.91.0-1.2-0.71.7
Area under the delay curve2.22.39.40.3-0.8-0.90.9-0.9-1.51.5-1.5-1.51.5-1.5-1.4-1.51.81.7-1.61.51.81.71.71.61.4-1.5-1.13.1
BMI with tail0.30.93.4-1.4-1.1-1.0-1.31.30.9-0.9-0.20.9-0.90.90.90.9-1.3-1.10.9-1.0-0.3-0.4-0.4-0.1-0.70.51.8-0.7
BMI without tail0.30.62.0-0.8-1.4-1.4-0.20.2-0.30.3-0.7-0.40.4-0.4-0.4-0.6-0.30.7-0.50.41.21.01.01.40.8-0.90.3-0.5
Body weight1.45.79.7-0.80.20.3-2.12.12.9-2.91.82.9-2.92.92.72.6-2.0-2.52.8-3.1-2.4-2.6-2.6-1.6-2.72.63.0-0.3
Weight adjusted by age0.91.03.51.41.91.90.6-0.60.3-0.31.80.5-0.50.50.5-0.0-0.10.20.6-0.8-1.2-1.3-1.3-1.5-0.71.00.4-1.4
Bone surface0.30.40.9-0.4-0.1-0.1-0.70.71.0-0.90.50.9-0.90.90.80.5-0.5-0.10.8-0.9-0.2-0.7-0.7-0.3-0.80.80.60.4
Bone volume0.10.10.80.2-0.1-0.10.2-0.2-0.10.10.0-0.10.1-0.1-0.2-0.50.30.9-0.30.10.60.20.20.40.2-0.2-0.20.7
Breakpoint value in progressive ratio session0.80.87.7-0.1-0.8-0.90.3-0.3-0.60.6-0.4-0.60.6-0.6-0.9-0.10.60.3-0.70.70.81.01.10.81.1-1.2-0.72.8
Number of licking bursts0.20.31.11.00.90.90.8-0.8-0.30.31.0-0.30.3-0.3-0.1-0.40.20.6-0.2-0.0-0.2-0.2-0.2-0.30.2-0.0-0.1-0.9
Context. condit. distance diff. score1.31.57.1-2.5-2.7-2.6-1.71.70.6-0.6-2.00.4-0.40.40.20.7-0.4-0.90.20.11.01.01.01.30.1-0.50.01.1
Locomotion velocity, session 13.53.86.0-0.60.81.0-1.51.52.2-2.21.62.2-2.22.22.01.8-2.1-1.62.3-2.3-2.1-2.4-2.4-2.2-2.32.52.0-0.8
Locomotion distance, session 12.33.04.3-0.80.30.5-1.61.62.1-2.11.02.0-2.02.01.91.9-1.7-1.62.0-2.0-1.7-2.0-1.9-1.7-2.12.11.9-0.7
Locomotion velocity, session 21.41.63.40.31.21.3-0.50.51.0-1.01.41.1-1.11.11.01.2-1.3-1.21.3-1.3-1.8-1.6-1.7-1.8-1.41.51.3-1.6
Locomotion distance, session 21.41.93.1-0.20.70.9-0.90.91.5-1.51.21.5-1.51.51.61.6-1.4-1.01.6-1.6-1.5-1.7-1.7-1.7-1.71.71.6-0.4
Locomotion velocity, session 30.10.10.50.10.10.2-0.20.20.2-0.2-0.20.2-0.20.20.30.3-0.0-0.40.3-0.2-0.3-0.3-0.3-0.4-0.30.30.30.7
Locomotion distance, session 30.50.50.9-0.10.30.4-0.50.50.8-0.80.20.8-0.80.80.60.8-0.4-1.00.8-0.8-0.8-0.9-0.9-0.9-0.90.90.70.6
Stereotopy head waving bouts, day 30.10.20.3-0.20.10.1-0.30.30.5-0.50.50.5-0.50.50.50.0-0.6-0.10.4-0.5-0.3-0.4-0.4-0.3-0.40.50.40.6
Stereotopy head waving duration, day 30.30.42.0-0.6-0.9-1.0-0.10.1-0.20.2-0.5-0.20.2-0.2-0.3-0.60.10.5-0.40.30.90.70.81.10.6-0.6-0.41.4
Locomotion velocity, session 70.20.20.8-0.20.10.2-0.40.40.4-0.40.30.3-0.30.30.20.8-0.8-0.90.5-0.3-0.6-0.4-0.4-0.7-0.40.40.00.1
Locomotion distance, session 70.81.02.20.90.50.41.2-1.2-1.21.20.1-1.21.2-1.2-1.3-1.10.61.0-1.11.20.70.80.80.21.1-0.9-1.50.7
Stereotopy head waving bouts, day 70.80.91.9-1.4-1.1-1.0-1.41.41.1-1.1-0.21.0-1.01.01.00.9-1.3-0.71.0-0.8-0.1-0.4-0.30.0-0.60.51.20.2
Stereotopy head waving duration, day 70.81.02.8-1.7-1.4-1.3-1.51.51.1-1.1-0.70.9-0.90.90.91.1-1.1-0.80.9-0.70.0-0.2-0.20.2-0.60.41.20.5
Locomotion velocity, session 80.60.71.6-1.2-1.0-0.9-1.31.31.0-1.0-0.70.9-0.90.90.80.9-0.5-0.70.9-0.8-0.3-0.4-0.40.1-0.70.51.00.1
Locomotion distance, session 80.60.92.2-1.5-1.2-1.1-1.41.41.1-1.1-0.51.0-1.01.01.01.2-0.8-0.80.9-0.8-0.2-0.3-0.3-0.0-0.70.50.90.3
Degree of sensitization distance1.71.73.01.30.90.81.7-1.7-1.61.60.6-1.51.5-1.5-1.4-1.70.81.6-1.41.40.81.01.00.31.5-1.2-1.6-0.4
Degree of sensitization stereotypy0.70.72.7-1.7-1.5-1.5-1.41.40.8-0.8-0.90.6-0.60.60.70.8-1.0-0.50.7-0.40.30.10.10.4-0.30.10.90.0
Conditioned locomotion1.92.23.50.7-0.4-0.51.2-1.2-1.71.7-1.6-1.71.7-1.7-1.6-1.41.91.4-1.81.81.51.71.61.31.6-1.7-1.31.2
Cocaine response after cond. corrected1.31.54.31.50.70.51.5-1.5-1.41.4-0.8-1.31.3-1.3-1.2-1.42.11.6-1.41.21.00.90.90.71.0-1.0-1.60.1
Cocaine response after cond. not corrected0.60.72.31.51.21.11.2-1.2-0.80.8-0.1-0.70.7-0.7-0.7-0.71.50.8-0.80.60.10.20.1-0.20.3-0.2-1.1-0.1
Cocaine response before conditioning1.41.63.2-1.0-0.2-0.1-1.41.41.5-1.50.71.4-1.41.41.31.7-1.4-1.81.5-1.4-1.4-1.2-1.2-1.0-1.41.31.2-0.3
Saline control response0.20.20.50.00.20.3-0.30.30.3-0.3-0.20.3-0.30.30.50.6-0.2-0.70.4-0.3-0.6-0.5-0.6-0.7-0.70.60.5-0.2
Bone: connectivity density0.50.73.3-1.6-1.8-1.8-1.11.10.5-0.5-0.90.4-0.40.40.50.3-0.5-0.00.2-0.10.90.60.61.00.0-0.30.31.2
Bone: cortical apparent density0.30.41.3-0.0-0.4-0.40.3-0.3-0.60.6-1.2-0.70.7-0.7-0.7-0.40.70.6-0.70.80.80.80.80.60.7-0.7-0.70.8
Bone: cortical area0.20.31.1-0.8-0.5-0.5-0.70.70.7-0.70.00.7-0.70.70.60.6-0.6-0.30.6-0.6-0.0-0.3-0.3-0.0-0.50.40.61.1
Bone: cortical porosity0.10.20.6-0.3-0.3-0.30.1-0.1-0.30.30.6-0.30.3-0.3-0.3-0.3-0.7-0.1-0.20.40.20.40.50.20.6-0.5-0.50.8
Bone: cortical porosity0.20.30.6-0.3-0.4-0.40.3-0.3-0.50.50.2-0.50.5-0.5-0.6-0.6-0.30.0-0.50.60.40.70.70.50.8-0.7-0.60.7
Bone: cortical thickness0.30.41.9-1.0-1.1-1.1-0.50.5-0.10.1-1.4-0.20.2-0.2-0.10.20.10.0-0.20.40.80.70.70.70.3-0.5-0.01.3
Bone: cortical thickness0.40.51.4-0.8-0.5-0.4-0.90.90.7-0.7-1.00.6-0.60.60.71.0-0.3-1.20.7-0.5-0.5-0.4-0.4-0.4-0.70.51.10.9
Bone: cortical tissue density0.40.51.4-0.0-0.4-0.40.4-0.4-0.70.7-1.2-0.80.8-0.8-0.8-0.50.80.6-0.70.90.80.90.90.70.8-0.8-0.80.8
Condit. Reinf. active minus inactive responses0.91.04.42.02.12.11.4-1.4-0.90.80.9-0.70.7-0.7-0.3-0.40.60.4-0.30.4-1.0-0.5-0.6-1.40.10.2-0.3-0.7
Condit. Reinf. active-inactive response ratio1.11.24.02.01.91.91.7-1.7-1.31.30.8-1.11.1-1.1-0.7-0.91.00.6-0.70.8-0.6-0.0-0.1-0.90.6-0.3-0.7-0.6
Condit. Reinf. active responses0.70.93.31.81.81.81.4-1.4-0.90.90.8-0.70.7-0.7-0.5-0.60.70.7-0.40.5-0.6-0.3-0.3-1.00.4-0.1-0.6-1.0
Condit. Reinf. inactive responses0.00.00.30.20.20.10.2-0.2-0.00.00.20.0-0.00.0-0.2-0.2-0.10.5-0.0-0.00.2-0.00.0-0.00.1-0.1-0.2-0.2
Incentive salience index mean1.31.56.02.52.32.31.9-1.9-1.21.21.0-1.01.0-1.0-0.6-0.91.31.0-0.70.6-0.6-0.3-0.4-1.10.4-0.1-0.6-1.1
Condit. Reinf. lever presses0.70.93.21.81.51.41.5-1.5-1.00.90.6-0.80.8-0.8-0.6-1.01.31.2-0.70.60.00.0-0.0-0.30.5-0.3-0.7-1.0
Condit. Reinf. active minus inactive responses0.70.92.0-0.00.70.8-0.50.50.8-0.91.10.9-0.90.90.80.9-1.1-1.21.1-1.0-1.4-1.2-1.2-1.3-0.91.10.9-0.6
Condit. Reinf. active-inactive response ratio0.10.10.50.40.70.70.2-0.20.1-0.10.70.2-0.20.2-0.10.2-0.2-0.20.3-0.3-0.6-0.5-0.5-0.7-0.20.40.2-0.1
Condit. Reinf. active responses2.83.97.30.31.61.8-0.90.91.8-1.82.41.9-1.91.91.91.8-2.1-1.92.3-2.2-2.7-2.6-2.5-2.6-2.12.32.0-1.3
Condit. Reinf. inactive responses3.84.67.50.11.41.6-1.21.22.1-2.12.62.1-2.12.12.31.9-2.5-2.02.5-2.5-2.7-2.7-2.7-2.6-2.32.62.3-1.3
Condit. Reinf. lever presses0.81.13.0-1.0-0.3-0.2-1.31.31.2-1.20.01.1-1.11.11.01.5-1.2-1.71.2-0.9-1.1-0.9-0.9-0.8-1.21.10.7-0.4
Condit. Reinf. lever reinforcers received2.53.56.50.01.31.5-1.01.01.7-1.82.11.8-1.81.81.81.8-2.2-2.02.2-2.0-2.5-2.4-2.3-2.4-2.02.21.9-1.2
Conditioned reinforcement - actives1.11.13.21.81.41.31.5-1.5-1.01.00.7-0.90.9-0.9-1.0-1.11.21.3-0.90.70.20.20.20.00.8-0.5-1.4-1.0
Conditioned reinforcement - inactives0.70.84.90.30.30.10.8-0.8-0.70.70.8-0.60.6-0.6-0.7-0.90.61.1-0.70.70.80.60.60.80.9-0.8-1.7-2.2
Conditioned locomotion0.10.11.10.30.50.50.3-0.3-0.30.20.0-0.20.2-0.2-0.2-0.10.60.3-0.10.3-0.1-0.00.0-0.20.10.0-0.6-1.0
Patch foraging indifference point 0 sec0.40.62.5-1.4-1.4-1.3-1.11.10.4-0.4-1.60.3-0.30.30.60.6-0.6-0.10.4-0.00.80.30.30.5-0.30.10.70.6
Patch foraging indifference point AUC7.38.414.0-3.2-1.8-1.6-3.73.73.7-3.70.23.5-3.53.53.33.0-3.0-3.43.3-3.2-1.8-2.2-2.1-1.1-2.92.63.4-0.6
Delay disc. indifference point, 0s delay1.11.22.9-0.10.40.6-0.70.71.1-1.10.21.2-1.21.21.21.2-1.0-1.01.1-1.3-1.2-1.3-1.4-1.3-1.41.41.70.3
Delay disc. indifference point, 16s delay5.25.214.30.2-1.6-1.81.1-1.1-2.12.1-2.5-2.32.3-2.3-2.2-2.32.82.1-2.42.32.72.72.72.72.3-2.5-2.03.8
Delay disc. indifference point, 2s delay1.11.32.90.6-0.2-0.31.0-1.0-1.21.2-0.9-1.21.2-1.2-1.2-1.11.71.6-1.31.11.41.21.11.11.0-1.1-0.81.3
Delay disc. indifference point, 24s delay1.31.34.3-0.8-1.6-1.7-0.20.2-0.60.6-2.1-0.80.8-0.8-0.7-1.11.00.6-0.90.91.61.41.41.60.8-1.1-0.61.8
Delay disc. indifference point, 4s delay1.31.44.10.0-0.7-0.80.6-0.6-1.21.2-1.5-1.21.2-1.2-1.2-1.21.41.3-1.31.21.51.41.31.11.1-1.2-0.72.0
Delay disc. indifference point, 8s delay0.40.43.50.3-0.1-0.10.5-0.5-0.60.6-0.4-0.50.5-0.5-0.5-0.50.70.7-0.60.50.60.50.50.50.4-0.5-0.31.9
Indifference point function ln k4.46.211.73.22.21.93.4-3.4-3.23.10.2-2.92.9-2.9-2.8-2.32.82.8-2.72.61.11.51.50.42.2-2.0-2.9-0.3
Indifference point function log k4.46.211.73.22.21.93.4-3.4-3.23.10.2-2.92.9-2.9-2.8-2.32.82.8-2.72.61.11.51.50.42.2-2.0-2.9-0.3
Patch foraging total patch changes 0 sec0.40.73.2-1.6-1.5-1.4-1.21.10.4-0.3-1.80.2-0.20.20.40.5-0.60.10.20.11.00.40.40.7-0.2-0.00.50.6
Patch foraging total patch changes 12 sec4.76.112.7-3.4-2.3-2.0-3.63.63.0-3.0-1.02.7-2.72.72.82.8-2.7-2.82.6-2.3-0.9-1.4-1.4-0.6-2.42.02.80.5
Patch foraging total patch changes 18 sec2.33.06.6-2.5-1.7-1.4-2.52.52.0-2.0-0.91.8-1.81.81.71.6-2.2-1.61.8-1.5-0.4-0.9-0.9-0.5-1.61.42.60.6
Patch foraging total patch changes 24 sec6.68.017.2-4.0-3.1-2.8-4.24.13.5-3.4-1.33.1-3.13.13.23.1-2.9-2.92.9-2.7-0.7-1.3-1.3-0.1-2.62.03.11.4
Patch foraging total patch changes 6 sec2.94.213.0-3.6-3.0-2.8-3.23.22.3-2.3-1.82.1-2.12.12.02.0-2.0-1.81.8-1.50.3-0.4-0.30.8-1.51.01.90.1
Patch foraging time to switch 0 sec2.94.58.02.61.41.22.8-2.8-2.62.60.6-2.42.4-2.4-2.4-2.61.82.5-2.32.11.21.51.50.72.3-1.9-2.30.9
Patch foraging water rate 0 sec0.81.44.0-2.0-1.6-1.5-1.81.81.2-1.1-1.91.0-1.01.01.21.3-0.3-1.30.9-0.70.0-0.2-0.30.3-1.00.61.2-0.0
Patch foraging water rate 12 sec0.10.10.30.20.10.10.3-0.3-0.40.4-0.5-0.40.4-0.4-0.4-0.10.40.5-0.30.30.40.20.20.10.2-0.20.00.5
Patch foraging water rate 18 sec0.40.51.10.10.60.7-0.30.30.6-0.60.50.6-0.60.60.70.7-0.7-0.40.8-0.7-0.8-0.9-0.9-1.0-0.70.80.8-0.7
Patch foraging water rate 24 sec0.70.93.6-1.9-1.8-1.8-1.41.40.7-0.7-1.70.5-0.50.50.40.9-0.2-0.50.4-0.10.70.40.40.8-0.3-0.00.40.7
Patch foraging water rate 6 sec0.30.51.40.1-0.3-0.40.5-0.5-0.70.7-0.9-0.70.7-0.7-0.7-0.61.20.9-0.90.80.90.80.80.80.6-0.7-0.70.2
Seeking ratio, delayed vs. immediate footshock0.70.82.8-1.7-1.5-1.5-1.41.40.9-0.9-1.10.8-0.80.80.60.9-0.5-0.90.5-0.50.20.10.10.8-0.60.30.10.5
Distance traveled before self-admin3.13.37.2-1.9-1.2-1.1-2.32.32.3-2.30.12.1-2.12.12.12.7-2.5-2.22.1-1.9-1.1-1.3-1.2-0.6-1.51.41.80.3
Distance traveled after self-admin1.01.13.7-1.1-1.0-1.0-1.41.41.4-1.3-0.01.2-1.21.21.21.1-1.9-1.11.1-1.0-0.2-0.5-0.4-0.1-0.70.60.70.2
Extensor digitorum longus weight0.20.71.8-0.3-0.9-1.00.2-0.2-0.70.7-1.3-0.80.8-0.8-0.8-0.81.10.3-0.91.01.11.21.11.20.8-1.0-0.50.3
Bone: elastic displacement0.10.10.6-0.6-0.6-0.6-0.30.3-0.10.1-0.8-0.20.2-0.20.1-0.1-0.00.1-0.10.30.50.40.40.40.1-0.2-0.20.5
Bone: elastic work0.30.30.6-0.40.00.1-0.60.60.7-0.70.20.6-0.60.60.70.7-0.6-0.60.7-0.6-0.5-0.6-0.6-0.5-0.70.70.40.3
Bone: endosteal estimation0.81.77.51.31.91.90.2-0.20.9-0.92.71.0-1.01.00.80.7-0.9-0.91.2-1.4-2.0-1.8-1.7-1.7-1.11.40.6-0.2
Bone: endosteal perimeter0.61.36.21.11.71.60.3-0.20.8-0.82.51.0-1.01.00.50.4-0.5-0.00.9-1.3-1.2-1.5-1.5-1.2-1.01.30.1-0.9
Epididymis fat weight0.71.53.10.61.21.3-0.30.31.2-1.31.71.3-1.31.31.21.0-0.8-0.61.3-1.6-1.5-1.7-1.7-1.1-1.31.51.3-0.8
Delta time in closed arm before/after self-admin0.80.83.6-1.5-1.8-1.8-1.11.10.4-0.3-1.90.1-0.10.10.30.30.6-0.2-0.00.11.00.70.71.4-0.0-0.30.40.8
Delta time in open arm before/after self-admin1.71.77.41.02.02.00.4-0.40.5-0.62.70.7-0.70.70.70.3-1.6-0.20.8-1.0-1.4-1.6-1.5-1.8-0.91.20.1-2.3
Diff in mean of infusions in LGA sessions0.60.62.9-0.7-1.1-1.2-0.20.1-0.40.4-0.5-0.40.4-0.4-0.70.10.10.5-0.40.61.31.01.11.00.9-0.9-0.81.7
Delay discount exponential model param2.32.59.4-0.20.91.0-0.90.91.5-1.51.51.5-1.51.51.51.6-1.9-1.71.7-1.5-1.9-1.8-1.7-1.6-1.51.61.0-3.1
Extinction: sum of active levers before priming0.30.34.1-0.1-0.3-0.3-0.40.40.5-0.4-0.60.5-0.50.50.20.50.5-0.50.2-0.4-0.0-0.1-0.20.2-0.50.3-0.02.0
Active lever presses in extinction session 60.40.45.70.2-0.0-0.10.3-0.3-0.50.5-0.2-0.50.5-0.5-0.50.20.2-0.1-0.40.50.10.40.4-0.20.5-0.5-0.52.4
Bone: final force0.61.01.8-0.30.20.3-0.80.81.1-1.11.21.1-1.11.10.91.3-1.0-1.31.2-1.2-1.2-1.1-1.1-0.9-1.01.00.80.3
Bone: final moment0.61.02.1-0.7-0.1-0.0-1.01.01.2-1.20.91.1-1.11.11.01.4-1.1-1.41.3-1.2-1.1-1.0-1.0-0.7-1.00.90.90.5
Food consumed during 24 hour testing period0.20.20.60.10.30.4-0.20.20.5-0.40.80.5-0.50.50.60.2-0.3-0.40.5-0.5-0.6-0.6-0.6-0.4-0.40.60.1-0.5
Glucose0.40.62.31.41.51.50.9-0.9-0.50.50.1-0.50.5-0.5-0.1-0.20.40.3-0.10.3-0.6-0.5-0.6-1.2-0.20.40.3-1.4
Heart weight1.41.97.9-2.4-2.7-2.6-2.02.01.0-1.0-2.80.8-0.80.80.51.50.4-0.90.3-0.31.00.70.61.5-0.7-0.00.60.3
Delay discount hyperbolic model param2.22.48.0-0.30.80.9-1.01.01.5-1.51.51.6-1.61.61.51.6-1.9-1.81.7-1.5-1.9-1.7-1.7-1.6-1.51.61.0-2.8
Intermittent access intake day 1-15 change0.00.00.30.40.10.00.2-0.2-0.20.2-0.2-0.20.2-0.2-0.2-0.40.30.2-0.20.00.10.10.0-0.10.1-0.10.5-0.1
Intermittent access intake escalation0.30.30.70.80.20.20.7-0.7-0.60.6-0.1-0.60.6-0.6-0.6-0.80.40.7-0.60.40.40.40.30.10.5-0.50.30.2
Intermittent access intake escalation 20.10.10.60.50.40.40.1-0.10.1-0.10.10.1-0.10.10.1-0.1-0.60.00.2-0.2-0.3-0.3-0.4-0.5-0.20.30.7-0.2
Intermitt. access day 1 inactive lever presses0.20.21.00.30.20.20.4-0.4-0.40.4-0.0-0.40.4-0.4-0.5-0.10.70.3-0.50.50.20.30.40.40.3-0.4-1.0-0.8
Intermitt. access day 15 inactive lever presses1.41.54.30.51.21.2-0.40.41.1-1.11.41.2-1.21.21.21.1-0.8-1.11.2-1.2-1.5-1.6-1.5-1.4-1.31.50.7-2.1
Intermitt. access escalation Index2.32.03.1-1.2-0.6-0.5-1.61.61.7-1.70.11.7-1.71.71.81.7-1.8-1.51.4-1.6-1.0-1.2-1.2-0.8-1.61.41.7-0.8
Intermittent access day 1 total infusions1.61.89.12.12.72.71.6-1.6-0.50.52.1-0.20.2-0.2-0.3-0.60.10.9-0.1-0.0-1.0-1.0-1.0-1.6-0.20.6-0.1-3.0
Intermittent access day 15 total infusions0.60.72.91.41.51.51.1-1.1-0.40.41.4-0.30.3-0.3-0.4-0.7-0.30.7-0.20.0-0.5-0.5-0.5-1.00.10.10.4-1.7
Intermittent access terminal intake (last 3 days)1.61.87.02.32.62.61.6-1.6-0.50.52.1-0.20.2-0.2-0.4-0.6-0.30.6-0.0-0.2-1.2-1.1-1.1-1.9-0.10.60.8-2.3
Intermittent access total infusions1.31.46.21.72.32.31.1-1.1-0.0-0.02.00.2-0.20.20.1-0.2-0.40.10.3-0.5-1.3-1.2-1.3-1.7-0.50.80.6-2.5
Intermittent access day 1 locomotion0.30.41.80.81.21.20.7-0.7-0.20.21.3-0.10.1-0.10.0-0.2-0.20.40.0-0.0-0.4-0.5-0.4-0.7-0.00.3-0.4-0.9
Intermittent access day 15 total locomotion1.21.32.60.2-0.4-0.50.8-0.8-1.31.3-0.1-1.31.3-1.3-1.3-1.40.51.4-1.11.41.31.31.40.91.6-1.4-1.50.9
Intermittent access total locomotion0.91.12.31.41.11.01.5-1.5-1.21.20.9-1.21.2-1.2-1.0-1.40.61.3-0.90.90.30.40.5-0.21.1-0.8-0.8-0.4
Intermittent access standard deviation0.60.61.30.60.40.41.0-1.0-1.01.00.2-1.01.0-1.0-1.0-1.10.80.9-0.80.90.50.60.60.30.9-0.8-0.3-0.4
Left kidney weight0.51.32.6-0.4-0.3-0.2-1.21.21.6-1.60.61.6-1.61.61.51.2-0.8-0.71.2-1.6-0.7-1.1-1.1-0.3-1.41.21.4-0.1
Right kidney weight1.13.05.0-1.7-1.2-1.0-2.22.22.2-2.2-0.12.0-2.02.02.02.1-1.5-2.01.9-2.0-1.1-1.3-1.3-0.3-1.91.52.1-0.2
Cocaine induced anxiety0.10.10.6-0.4-0.4-0.4-0.40.40.3-0.3-0.50.3-0.30.30.20.10.4-0.10.2-0.20.2-0.0-0.00.6-0.20.1-0.2-0.8
Post-drug Anxiety0.91.02.71.20.80.71.1-1.1-1.21.2-0.6-1.11.1-1.1-1.2-1.11.60.9-0.91.10.40.60.50.30.8-0.7-0.9-0.8
Baseline Anxiety0.70.81.51.10.90.91.2-1.2-1.11.10.1-1.21.2-1.2-1.0-1.10.11.0-0.91.00.30.40.4-0.40.8-0.6-0.3-0.1
Tail length0.10.41.70.4-0.4-0.50.3-0.3-0.40.4-0.2-0.40.4-0.4-0.4-0.80.81.0-0.60.40.90.70.71.30.7-0.7-0.60.8
Length with tail0.51.73.30.70.90.9-0.60.61.6-1.61.41.6-1.61.61.41.20.2-0.81.4-1.8-1.4-1.7-1.7-0.7-1.61.61.00.4
Length without tail1.84.06.60.11.21.3-1.31.32.3-2.31.72.3-2.32.32.22.2-0.8-2.12.2-2.5-2.4-2.5-2.6-2.0-2.62.51.8-0.4
Times rat made contact with spout0.80.93.20.51.31.3-0.00.00.8-0.81.80.9-0.90.90.60.5-0.7-0.60.9-1.0-1.3-1.3-1.3-1.3-0.91.10.10.0
Lifetime Intake1.61.87.32.02.72.71.2-1.2-0.0-0.02.30.3-0.30.30.1-0.2-0.30.20.4-0.6-1.6-1.4-1.5-1.9-0.61.00.5-2.1
Liver weight, left2.54.07.30.01.51.7-0.90.91.8-1.82.41.8-1.81.82.11.5-2.5-1.52.3-2.2-2.4-2.6-2.6-2.7-2.12.42.7-1.6
Liver weight, right1.01.75.40.00.91.0-0.60.61.3-1.32.31.3-1.31.31.40.8-1.7-1.21.4-1.6-1.7-1.6-1.5-1.5-1.21.41.2-0.8
Locomotor activity3.96.39.5-0.80.70.9-2.12.12.8-2.81.62.8-2.82.82.72.7-2.3-2.72.9-2.9-2.8-2.9-2.9-2.7-2.93.03.10.8
Locomotor testing distance3.05.17.0-1.5-0.00.2-2.22.22.6-2.61.02.6-2.62.62.62.6-2.3-2.62.6-2.5-2.3-2.3-2.3-2.1-2.62.62.61.1
Locomotor testing rearing3.25.07.6-2.0-0.7-0.4-2.62.62.8-2.80.72.7-2.72.72.72.3-2.4-2.32.6-2.6-1.6-2.1-2.0-1.3-2.62.52.50.6
Locomotion in novel chamber1.21.53.4-0.7-0.2-0.1-1.31.31.4-1.4-0.11.3-1.31.31.31.6-1.2-1.61.3-1.2-1.3-1.1-1.1-1.0-1.31.21.9-0.2
Locomotion in novel chamber post-restriction0.50.61.20.20.00.0-0.70.71.0-1.0-0.40.9-0.90.90.91.00.3-0.90.7-0.9-0.6-0.8-0.8-0.2-1.10.90.70.4
Fecal boli incidents, locomotor time 10.91.02.50.70.90.9-0.40.41.0-1.1-0.11.0-1.01.01.11.10.4-0.70.9-1.3-1.0-1.3-1.5-1.0-1.61.41.2-0.5
Change in fecal boli incidents, locomotor task1.81.76.3-2.5-2.0-1.9-2.12.11.4-1.3-0.91.2-1.21.21.21.2-1.9-1.51.1-0.70.0-0.10.00.3-0.70.50.70.9
Time >=10cm from walls, locomotor time 10.70.71.4-1.0-0.5-0.5-1.01.01.0-1.00.31.0-1.01.01.11.2-1.2-1.00.8-0.8-0.6-0.5-0.5-0.4-0.70.50.9-0.6
Bouts of movement, locomotor time 10.30.32.41.00.50.50.6-0.6-0.50.5-0.8-0.50.5-0.5-0.5-0.31.60.2-0.50.4-0.10.20.10.20.1-0.2-0.6-0.0
Total resting periods, locomotor time 10.30.32.11.10.70.60.6-0.6-0.50.5-0.6-0.50.5-0.5-0.4-0.41.40.2-0.40.4-0.10.0-0.10.10.0-0.1-0.4-0.9
Rest time, locomotor task time 10.20.23.50.30.40.4-0.10.10.2-0.2-0.60.1-0.10.10.20.20.0-0.40.3-0.2-0.3-0.4-0.5-0.2-0.40.30.5-1.9
Distance moved, locomotor task time 10.50.52.0-1.4-1.1-1.0-1.01.00.7-0.70.50.7-0.70.70.60.6-0.9-0.50.5-0.50.00.00.10.3-0.30.20.11.4
Vertical activity count, locomotor time 10.20.20.9-0.5-0.6-0.7-0.10.10.00.00.90.1-0.10.10.1-0.1-0.70.6-0.20.00.60.40.50.50.5-0.4-0.50.8
Time >=10cm from walls, locomotor time 22.83.04.9-1.00.10.3-1.61.61.9-1.91.02.0-2.02.02.02.1-1.9-1.91.9-1.9-1.6-1.8-1.8-1.6-2.02.02.2-0.5
Bouts of movement, locomotor time 20.10.10.3-0.2-0.2-0.2-0.30.30.3-0.30.10.3-0.30.30.40.40.5-0.30.2-0.3-0.3-0.1-0.10.1-0.20.10.30.2
Total resting periods, locomotor time 20.10.20.4-0.3-0.3-0.3-0.50.50.5-0.50.00.5-0.50.50.60.60.4-0.40.4-0.5-0.3-0.2-0.20.2-0.30.30.30.3
Rest time, locomotor task time 20.50.61.4-1.0-1.0-1.0-1.21.21.0-1.0-1.20.8-0.80.80.90.9-0.3-0.80.6-0.60.1-0.2-0.20.6-0.60.30.60.2
Distance moved, locomotor task time 20.20.30.70.70.70.70.7-0.7-0.60.60.9-0.60.6-0.6-0.7-0.5-0.20.5-0.40.5-0.10.10.1-0.50.3-0.1-0.30.3
Vertical activity count, locomotor time 21.21.32.91.41.31.21.7-1.6-1.41.41.1-1.11.1-1.1-1.1-1.20.21.7-1.10.80.50.40.3-0.40.9-0.7-0.5-1.6
Light reinforcement 10.91.52.9-0.8-0.5-0.4-1.51.51.7-1.6-0.61.5-1.51.51.51.7-0.7-1.21.4-1.3-0.6-1.1-1.1-0.4-1.61.31.6-0.3
Light reinforcement 20.70.91.8-1.0-0.9-0.9-1.31.31.3-1.2-0.71.1-1.11.11.31.2-0.3-0.90.8-0.9-0.1-0.5-0.50.5-1.00.70.7-0.7
Bone: marrow area0.71.56.81.21.71.70.2-0.20.8-0.82.60.9-0.90.90.80.6-0.9-0.81.1-1.3-1.9-1.7-1.6-1.6-1.01.30.6-0.1
Bone: maximum diameter0.50.91.6-0.7-0.1-0.0-0.90.91.3-1.30.91.3-1.31.31.10.8-0.9-0.51.0-1.3-0.5-1.0-0.9-0.4-1.11.10.70.2
Bone: maximum force0.71.22.30.10.70.8-0.60.71.1-1.11.11.1-1.11.11.11.4-0.6-1.31.3-1.3-1.5-1.4-1.4-1.3-1.31.31.00.7
Bone: maximum moment0.91.52.6-0.20.40.5-1.01.01.4-1.31.01.3-1.31.31.31.6-0.8-1.61.4-1.4-1.6-1.4-1.4-1.3-1.41.31.20.8
Mean time between licks in bursts2.63.68.32.92.22.02.8-2.8-2.22.21.0-1.91.9-1.9-2.2-2.22.22.3-1.81.60.50.80.7-0.11.6-1.2-2.01.1
Mean num. licks in bursts0.20.31.3-0.8-0.4-0.4-0.70.70.6-0.5-0.00.6-0.60.60.20.6-0.6-0.80.5-0.3-0.3-0.3-0.2-0.1-0.40.3-0.11.2
Cd content in liver0.60.61.90.30.91.0-0.20.20.6-0.61.00.6-0.60.60.70.5-0.8-0.60.8-0.8-1.1-1.1-1.1-1.4-0.91.01.1-0.1
Co content in liver0.91.13.30.61.11.1-0.20.20.9-0.91.80.9-0.90.90.80.8-1.1-0.91.0-1.2-1.5-1.4-1.3-1.4-0.91.10.70.2
Cu content in liver2.93.55.3-0.50.80.9-1.41.42.0-2.01.92.0-2.02.01.71.8-2.1-2.12.1-2.2-2.3-2.2-2.2-2.0-2.22.21.9-1.5
Fe content in liver0.20.30.60.60.70.70.0-0.00.4-0.40.10.4-0.40.40.50.40.4-0.10.4-0.6-0.6-0.7-0.8-0.7-0.70.70.60.2
K content in liver1.21.22.3-1.0-0.4-0.4-1.21.21.5-1.50.71.5-1.51.51.41.0-0.8-0.71.2-1.4-0.5-1.0-0.9-0.0-1.21.10.8-1.1
Mg content in liver2.42.54.3-1.4-0.5-0.4-1.81.82.1-2.10.92.0-2.02.01.91.7-1.6-1.41.8-1.9-1.1-1.5-1.4-0.6-1.81.61.4-1.1
Mn content in liver0.10.10.30.0-0.1-0.20.2-0.2-0.20.20.1-0.20.2-0.2-0.1-0.20.30.1-0.30.20.20.30.40.40.4-0.3-0.50.1
Na content in liver0.91.02.7-1.7-1.1-1.1-1.41.41.2-1.20.31.1-1.11.11.10.9-1.4-1.21.0-0.9-0.3-0.4-0.30.2-0.60.50.7-0.6
Rb content in liver0.30.31.6-1.3-1.2-1.2-0.70.70.1-0.1-0.60.0-0.00.0-0.20.3-0.7-0.3-0.10.30.60.50.60.50.2-0.3-0.20.1
Se content in liver2.93.66.30.21.21.4-1.11.12.0-2.01.62.0-2.02.02.11.8-1.1-1.82.1-2.4-2.4-2.4-2.5-2.1-2.42.42.2-0.4
Sr content in liver0.20.20.8-0.9-0.6-0.5-0.50.50.2-0.2-0.10.2-0.20.20.30.2-0.6-0.30.2-0.10.10.10.10.1-0.0-0.00.3-0.9
Zn content in liver0.40.41.60.50.40.40.7-0.7-0.70.7-0.2-0.70.7-0.7-0.8-0.70.40.6-0.70.80.40.40.40.10.5-0.4-0.7-1.3
Bone: minimum diameter0.40.74.31.21.61.60.7-0.70.1-0.12.10.2-0.20.20.10.1-0.40.10.4-0.5-1.0-1.0-0.9-1.1-0.30.6-0.2-0.3
Time in familiar zone, hab. session 10.10.10.60.1-0.1-0.20.2-0.2-0.40.4-0.4-0.40.4-0.4-0.4-0.10.4-0.1-0.30.40.10.40.40.30.4-0.4-0.2-0.8
Time in novel zone, hab. session 10.80.83.5-1.6-1.9-1.9-0.90.90.1-0.1-1.2-0.00.0-0.0-0.10.0-0.40.2-0.20.31.20.91.01.20.5-0.7-0.01.3
Total zone transitions, hab. session 10.30.41.9-0.8-1.1-1.0-0.30.3-0.20.2-1.4-0.20.2-0.2-0.0-0.00.30.6-0.40.51.00.80.80.80.3-0.50.00.7
Total locomotion distance, hab. session 10.81.23.6-1.0-1.7-1.7-0.20.2-0.50.5-1.9-0.60.6-0.6-0.5-0.70.61.2-0.90.91.81.41.41.60.9-1.1-0.00.8
Locomotion velocity, hab. session 10.50.82.4-0.6-1.2-1.3-0.00.0-0.50.5-1.2-0.50.5-0.5-0.4-0.80.61.1-0.80.71.61.11.11.40.8-0.9-0.31.0
Time in familiar zone, hab. session 20.20.21.40.70.70.60.4-0.40.0-0.01.20.1-0.10.10.0-0.1-0.20.10.1-0.3-0.4-0.4-0.3-0.40.00.1-0.40.2
Time in novel zone, hab. session 21.81.87.0-2.7-2.2-2.1-2.12.11.3-1.2-1.51.0-1.01.01.11.6-1.2-1.61.0-0.60.20.10.10.5-0.80.41.20.6
Total zone transitions, hab. session 22.53.25.0-1.3-0.2-0.0-1.91.92.2-2.20.62.2-2.22.22.22.2-1.8-1.72.1-2.1-1.4-1.8-1.8-1.3-2.22.11.90.1
Total locomotion distance, hab. session 21.01.42.3-1.3-0.8-0.6-1.51.51.5-1.5-0.01.4-1.41.41.51.4-1.2-0.91.3-1.3-0.5-0.9-0.9-0.4-1.31.11.50.2
Locomotion velocity, hab. session 20.60.81.6-0.9-0.5-0.4-1.11.11.2-1.20.11.1-1.11.11.20.9-1.1-0.41.0-1.0-0.3-0.7-0.7-0.3-1.00.91.2-0.2
Novel to familiar place preference ratio2.62.712.4-3.0-3.5-3.5-1.61.60.3-0.3-2.50.0-0.00.00.0-0.2-0.30.5-0.40.62.41.81.82.70.7-1.20.10.5
Novelty place preference3.13.214.9-3.3-3.9-3.9-1.91.90.5-0.5-2.50.2-0.20.20.1-0.1-0.40.4-0.30.42.51.81.92.90.7-1.20.10.9
Time in novel zone, NPP test3.63.717.5-3.8-4.2-4.2-2.32.30.8-0.8-2.50.5-0.50.50.40.3-0.9-0.00.00.22.41.71.82.80.5-1.10.41.1
Total zone transitions, NPP test1.72.44.3-0.20.70.9-1.11.11.6-1.60.81.7-1.71.71.91.6-1.4-1.41.8-1.8-1.7-1.9-1.9-1.9-2.02.11.8-0.4
Total locomotion distance, NPP test0.70.92.2-0.10.40.6-0.70.71.0-1.00.21.0-1.01.01.20.8-0.8-0.71.0-1.1-1.0-1.2-1.2-1.2-1.21.31.5-0.5
Locomotion velocity, NPP test0.60.91.80.20.80.9-0.40.40.8-0.90.40.9-0.90.91.10.6-0.6-0.50.9-1.0-1.0-1.2-1.3-1.3-1.21.31.4-0.6
Intraocular pressure0.10.11.10.50.30.30.0-0.00.1-0.1-0.50.1-0.10.10.00.51.0-0.50.0-0.1-0.4-0.2-0.30.0-0.40.3-0.40.8
Delta distance traveled before/after self-admin0.20.21.00.70.30.30.6-0.6-0.40.40.4-0.40.4-0.4-0.4-1.0-0.10.9-0.40.30.40.20.2-0.00.4-0.3-0.40.2
Delta ambulatory time before/after self-admin1.61.74.00.8-0.0-0.21.2-1.2-1.61.6-0.4-1.61.6-1.6-1.5-2.00.81.6-1.51.51.41.41.30.91.5-1.4-1.40.6
Parametrial fat weight0.91.83.01.60.80.71.7-1.7-1.71.70.1-1.61.6-1.6-1.6-1.61.31.5-1.41.30.81.01.00.41.5-1.3-1.3-0.2
Pavlov. Cond. lever latency1.11.35.8-2.4-2.3-2.2-1.71.71.0-0.9-1.10.7-0.70.70.50.7-1.4-0.80.6-0.30.80.50.50.9-0.2-0.10.61.0
Pavlov. Cond. magazine entry latency1.01.32.51.41.11.01.6-1.6-1.41.40.6-1.31.3-1.3-1.2-1.40.71.4-1.01.10.40.60.60.11.2-0.9-1.0-0.7
Pavlov. Cond. change in total contacts1.51.64.92.21.71.61.9-1.9-1.51.50.0-1.41.4-1.4-1.1-1.41.81.3-1.21.10.10.40.3-0.20.9-0.6-0.8-0.8
Pavlov. Cond. index score0.91.24.72.22.01.91.7-1.7-1.11.11.1-0.90.9-0.9-0.6-1.00.91.2-0.60.5-0.4-0.2-0.3-0.70.5-0.2-0.4-0.9
Pavlov. Cond. latency score1.11.35.72.42.22.21.8-1.8-1.01.01.1-0.80.8-0.8-0.5-0.91.11.1-0.60.4-0.6-0.4-0.5-0.90.30.0-0.4-1.0
Pavlov. Cond. lever contacts1.41.67.02.72.32.22.0-2.0-1.21.20.6-1.01.0-1.0-0.6-1.01.81.3-0.80.6-0.5-0.2-0.3-0.70.4-0.1-0.6-0.9
Pavlov. Cond. magazine entry number1.11.42.9-1.5-1.1-1.1-1.71.71.5-1.5-0.71.4-1.41.41.11.6-0.5-1.61.1-1.2-0.5-0.6-0.6-0.1-1.41.01.00.5
Pavlov. Cond. intertrial magazine entries1.61.93.40.20.91.0-0.80.81.4-1.40.91.5-1.51.51.51.5-0.4-1.21.4-1.7-1.8-1.7-1.8-1.6-1.91.81.6-1.2
Pavlov. Cond. lever-magazine prob. diff.1.11.44.82.21.91.81.8-1.8-1.31.20.9-1.11.1-1.1-0.8-1.21.11.5-0.80.7-0.10.0-0.0-0.50.7-0.4-0.6-0.9
Pavlov. Cond. response bias0.81.02.21.51.11.11.5-1.5-1.21.20.5-1.11.1-1.1-0.7-1.30.81.5-0.80.90.30.40.4-0.11.0-0.7-0.6-0.7
Pavlov. Cond. lever latency0.91.22.91.50.90.71.6-1.6-1.31.30.3-1.21.2-1.2-1.1-1.61.31.7-1.20.90.80.70.60.51.1-0.9-0.8-0.4
Pavlov. Cond. magazine entry latency0.20.30.60.00.40.4-0.30.30.5-0.50.40.5-0.50.50.30.7-0.3-0.60.5-0.4-0.7-0.6-0.6-0.5-0.60.60.1-0.8
Pavlov. Cond. change in total contacts1.62.24.5-0.50.60.7-1.11.11.6-1.61.71.6-1.61.61.41.5-2.1-1.61.8-1.6-1.8-1.8-1.7-1.7-1.51.71.2-0.1
Pavlov. Cond. index score0.50.71.5-0.7-0.10.0-0.90.90.9-0.90.50.9-0.90.90.81.1-1.1-1.21.0-0.8-1.0-0.8-0.8-0.8-0.90.90.50.1
Pavlov. Cond. latency score0.40.41.0-0.40.10.2-0.60.60.7-0.70.40.7-0.70.70.61.0-0.9-1.00.8-0.6-0.9-0.7-0.6-0.7-0.70.70.3-0.0
Pavlov. Cond. lever contacts0.70.92.4-1.5-1.1-1.0-1.41.41.0-1.0-0.60.9-0.90.90.81.4-1.1-1.50.9-0.6-0.5-0.3-0.3-0.2-0.80.60.50.7
Pavlov. Cond. magazine entry number0.30.41.00.50.0-0.00.6-0.6-0.70.7-0.7-0.70.7-0.7-0.5-0.71.00.6-0.80.70.60.60.60.40.5-0.6-0.30.5
Pavlov. Cond. intertrial magazine entries0.50.61.6-0.50.00.2-0.70.70.8-0.80.60.8-0.80.80.90.6-1.0-0.90.9-0.9-0.8-0.8-0.8-0.8-0.80.81.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.60.81.5-0.50.10.2-0.80.81.0-1.00.71.0-1.01.00.91.2-1.2-1.21.1-0.9-1.1-1.0-0.9-0.9-0.91.00.6-0.1
Pavlov. Cond. response bias0.40.61.4-1.1-0.6-0.5-1.01.00.9-0.90.00.8-0.80.80.71.0-1.1-1.20.8-0.6-0.6-0.5-0.4-0.4-0.70.60.40.1
Time in closed arm before self-admin1.21.43.11.41.11.01.7-1.8-1.41.41.0-1.41.4-1.4-1.3-1.20.11.4-1.11.10.30.70.7-0.31.4-1.1-1.11.0
Time in closed arm after self-admin0.20.20.9-0.3-0.5-0.50.1-0.1-0.30.3-0.9-0.40.4-0.4-0.4-0.00.90.2-0.50.50.50.60.60.80.3-0.4-0.20.7
Time in open arm before self-admin1.11.14.5-1.3-2.1-2.1-0.80.8-0.10.1-1.7-0.30.3-0.3-0.3-0.30.70.1-0.30.61.41.31.32.10.8-1.1-0.50.7
Time in open arm after self-admin0.70.72.9-0.8-0.4-0.5-1.01.01.0-1.00.41.0-1.01.01.00.7-1.7-0.80.9-0.9-0.2-0.6-0.6-0.3-0.70.60.5-1.2
Bone: periosteal estimation0.40.83.40.51.01.0-0.00.00.7-0.71.80.7-0.70.70.60.6-0.8-0.60.9-1.0-1.2-1.2-1.1-1.1-0.70.90.40.6
Bone: periosteal perimeter0.40.71.6-0.20.30.4-0.60.61.1-1.11.21.1-1.11.10.70.8-0.7-0.60.9-1.2-0.8-1.0-1.0-0.5-1.01.00.40.2
Bone: post-yield work0.81.12.91.41.71.70.3-0.30.5-0.51.50.6-0.60.60.80.80.2-0.60.7-1.0-1.7-1.4-1.5-1.6-1.01.10.9-0.6
Progressive ratio test 1 active lever presses0.70.71.40.51.01.0-0.10.10.8-0.81.10.9-0.90.90.80.7-0.7-0.60.9-0.9-1.1-1.2-1.2-1.1-0.91.10.4-1.0
Progressive ratio test 1 breakpoint0.60.61.70.81.31.30.2-0.20.4-0.51.20.6-0.60.60.50.4-0.4-0.30.6-0.7-1.0-1.1-1.1-1.2-0.70.90.3-1.0
Progressive ratio test 1 inactive lever presses0.80.91.90.30.80.8-0.50.51.0-1.01.01.1-1.11.11.11.1-0.3-0.61.0-1.1-1.0-1.2-1.2-0.8-1.21.20.2-1.4
Progressive ratio test 2 active lever presses1.21.32.51.01.41.50.1-0.10.8-0.81.60.9-0.90.91.00.4-1.3-0.21.0-1.1-1.3-1.5-1.5-1.6-0.91.21.2-1.5
Progressive ratio test 2 breakpoint1.21.33.00.71.21.2-0.20.21.0-1.01.41.0-1.01.01.10.5-1.6-0.41.1-1.2-1.2-1.5-1.5-1.7-1.01.21.4-1.7
Progressive ratio test 2 inactive lever presses0.70.84.91.11.51.50.5-0.50.2-0.21.50.3-0.30.30.30.0-0.50.20.4-0.5-0.9-1.0-1.0-1.2-0.50.80.2-2.2
Incentive Sensitization - Responses0.40.52.21.11.01.00.5-0.50.1-0.11.10.1-0.10.10.1-0.3-1.30.40.2-0.3-0.5-0.6-0.6-1.0-0.00.30.4-1.5
Incentive Sensitization - Breakpoint0.50.52.41.21.21.20.6-0.60.0-0.11.20.1-0.10.10.1-0.4-1.30.40.2-0.2-0.5-0.6-0.6-1.1-0.00.30.4-1.6
Sum of active levers in priming session hrs 5-60.10.10.30.40.50.50.5-0.5-0.40.40.4-0.20.2-0.2-0.30.00.00.1-0.20.2-0.00.00.0-0.30.2-0.2-0.4-0.3
Progressive ratio0.70.82.1-1.4-0.9-0.7-1.31.31.0-1.0-0.60.9-0.90.91.20.6-1.1-0.60.9-0.8-0.0-0.5-0.5-0.2-1.00.81.3-0.3
Food seeking constrained by brief footshock1.82.33.60.2-0.3-0.41.3-1.3-1.91.9-0.8-1.81.8-1.8-1.9-1.61.01.4-1.81.91.51.71.71.31.7-1.7-1.90.6
Seeking ratio, punishment vs. effort2.63.25.81.50.50.32.0-2.0-2.12.1-0.3-2.12.1-2.1-2.4-1.61.81.6-2.02.01.11.71.71.22.1-2.0-2.31.0
Retroperitoneal fat weight1.03.27.40.20.91.1-1.01.01.9-1.91.62.0-2.02.02.11.6-1.3-1.42.0-2.4-2.0-2.2-2.3-1.9-2.12.22.7-0.9
Reaction time number correct0.50.71.50.71.21.20.0-0.00.5-0.50.70.6-0.60.60.80.5-0.3-0.60.7-0.8-1.2-1.1-1.2-1.1-0.91.00.6-0.9
Reaction time mean minus median2.93.86.62.21.00.92.5-2.5-2.42.4-0.0-2.32.3-2.3-2.5-2.52.12.6-2.12.11.41.61.50.82.1-1.9-1.60.1
Reaction time mean minus median AUC1.51.93.61.20.40.31.6-1.6-1.71.7-0.3-1.61.6-1.6-1.9-1.61.51.7-1.61.51.11.31.20.71.5-1.4-1.00.5
Reaction time num false alarms1.31.83.4-1.6-0.9-0.8-1.81.81.6-1.6-0.51.5-1.51.51.81.6-1.3-1.61.5-1.3-0.8-0.9-0.9-0.6-1.51.21.5-0.1
Reaction time num false alarms AUC1.01.42.4-1.3-0.6-0.4-1.51.51.4-1.4-0.21.3-1.31.31.61.4-1.2-1.51.3-1.2-1.0-1.0-0.9-0.8-1.31.21.40.2
Reaction time trials correct on left0.50.71.50.71.21.20.0-0.00.5-0.50.70.6-0.60.60.80.5-0.3-0.60.7-0.8-1.2-1.1-1.2-1.1-0.91.00.6-0.9
Reaction time trials on left0.40.61.80.81.31.30.2-0.10.4-0.40.70.5-0.50.50.70.4-0.2-0.40.7-0.7-1.2-1.1-1.2-1.1-0.81.00.6-0.9
Reaction time mean2.53.58.12.92.01.82.7-2.7-2.32.20.8-2.12.1-2.1-2.3-2.11.82.1-1.81.70.50.90.8-0.21.7-1.3-1.80.3
Reaction time mean AUC2.63.57.72.81.81.62.6-2.6-2.32.30.4-2.12.1-2.1-2.4-2.12.02.1-1.91.80.71.00.9-0.01.7-1.4-1.80.4
Median of all reaction times2.02.76.62.61.81.62.4-2.4-2.02.00.7-1.81.8-1.8-2.0-1.71.61.7-1.61.50.40.80.7-0.21.5-1.2-1.80.5
Reaction time omissions2.53.56.32.21.31.12.4-2.4-2.32.3-0.3-2.12.1-2.1-2.2-2.52.02.4-2.02.01.31.31.20.71.8-1.5-1.5-0.8
Reaction time false alarm rate0.60.93.0-1.7-1.3-1.2-1.41.41.0-1.0-0.70.8-0.80.81.01.0-1.0-1.00.8-0.7-0.1-0.2-0.10.0-0.70.51.00.6
Reaction time premature initiation rate0.30.41.1-0.8-0.3-0.3-0.70.70.8-0.80.90.7-0.70.70.70.5-1.1-0.40.7-0.7-0.2-0.4-0.3-0.0-0.40.40.3-0.2
Reaction time premature initiations0.60.81.7-0.20.50.6-0.50.51.0-1.01.31.0-1.01.01.10.8-1.2-0.81.0-1.0-1.0-1.1-1.0-0.8-0.91.00.6-0.5
Std. dev. reaction times2.84.06.92.21.11.02.5-2.5-2.52.50.1-2.42.4-2.4-2.6-2.32.02.4-2.22.21.31.61.50.62.2-1.9-1.70.3
Reaction time trials completed0.40.61.80.81.31.30.2-0.10.4-0.40.70.5-0.50.50.70.4-0.2-0.40.7-0.7-1.2-1.1-1.2-1.1-0.81.00.6-0.9
Reaction time trials AUC0.40.51.70.91.21.30.2-0.20.3-0.30.60.4-0.40.40.60.4-0.2-0.40.6-0.6-1.2-1.0-1.1-1.1-0.70.90.5-0.8
Run reversals in cocaine runway, females0.80.81.5-0.7-0.9-1.00.2-0.2-0.90.9-0.7-0.90.9-0.9-1.0-0.9-0.30.5-0.81.11.11.21.20.91.2-1.2-0.7-0.7
Run reversals in cocaine runway, males3.53.46.42.51.71.52.5-2.5-2.32.30.2-2.22.2-2.2-2.2-1.72.01.6-1.81.90.51.11.0-0.11.9-1.5-1.81.6
Latency to leave start box in cocaine runway1.41.53.51.10.60.51.5-1.5-1.41.40.9-1.31.3-1.3-1.2-1.80.91.9-1.21.21.00.91.00.71.6-1.2-1.7-0.5
Latency to leave start box in cocaine runway, F0.30.41.10.70.60.60.8-0.8-0.50.51.0-0.50.5-0.5-0.4-0.90.21.1-0.30.30.30.20.20.00.6-0.3-0.6-1.1
Latency to leave start box in cocaine runway, M2.22.14.41.00.20.11.6-1.6-1.61.60.2-1.61.6-1.6-1.6-1.81.21.8-1.51.51.31.41.51.31.9-1.6-2.10.7
Std. dev. time between licks in bursts0.20.31.41.01.11.20.7-0.7-0.40.40.3-0.20.2-0.2-0.3-0.20.50.4-0.10.2-0.4-0.3-0.4-0.9-0.10.3-0.0-0.2
Total sessions with >9 infusions0.91.02.51.41.51.41.6-1.6-1.21.10.9-1.01.0-1.0-1.2-0.91.20.8-0.90.9-0.20.20.2-0.30.7-0.5-1.4-0.3
Short access day 1 total inactive lever presses0.10.11.80.50.40.40.1-0.10.1-0.10.10.2-0.20.20.00.10.90.40.0-0.20.0-0.2-0.3-0.1-0.30.30.1-1.3
Short access day 10 total inactive lever presses0.60.72.5-1.1-1.6-1.6-0.60.60.00.0-1.4-0.20.2-0.2-0.2-0.10.60.2-0.30.41.10.91.01.60.4-0.7-0.30.6
Short access day 1 total infusions0.91.04.31.62.02.10.9-0.90.1-0.11.60.3-0.30.30.20.20.5-0.10.4-0.6-1.4-1.2-1.2-1.5-0.60.9-0.1-0.5
Short access day 10 total infusions0.70.83.31.21.81.80.7-0.70.2-0.21.70.4-0.40.40.20.1-0.20.20.4-0.6-0.9-1.1-1.1-1.2-0.50.80.0-1.4
Short access total infusions1.51.77.31.82.72.71.1-1.10.1-0.22.30.4-0.40.40.30.1-0.3-0.10.6-0.7-1.7-1.6-1.6-2.1-0.71.20.4-1.5
Short access day 1 locomotion0.90.91.7-1.2-0.7-0.7-1.21.21.3-1.30.41.3-1.31.31.11.3-0.6-1.11.0-1.0-0.5-0.6-0.5-0.0-0.80.70.11.0
Short access day 10 total locomotion1.21.42.60.2-0.2-0.31.1-1.1-1.41.40.3-1.31.3-1.3-1.3-1.50.41.6-1.31.31.31.31.40.91.6-1.4-1.40.2
Short access total locomotion0.20.21.50.10.60.60.1-0.10.3-0.31.20.4-0.40.40.30.3-0.6-0.30.4-0.4-0.6-0.5-0.4-0.7-0.20.4-0.20.2
One hour access (0.3 mA shock)0.91.04.81.21.71.70.5-0.50.4-0.41.40.5-0.50.50.40.1-1.6-0.00.6-0.6-1.1-1.2-1.1-1.4-0.50.90.0-2.2
Compulsive drug intake0.10.11.10.10.20.20.1-0.1-0.10.1-0.3-0.20.2-0.2-0.1-0.1-1.0-0.1-0.20.2-0.10.0-0.0-0.2-0.10.1-0.0-0.3
One hour access (shock baseline)0.80.95.61.21.71.70.6-0.60.1-0.21.70.4-0.40.40.30.0-0.50.10.5-0.5-1.0-1.0-1.0-1.2-0.40.7-0.0-2.4
Social response proportion1.11.23.41.81.31.31.6-1.6-1.51.5-0.7-1.41.4-1.4-1.0-0.81.50.8-1.11.2-0.00.40.2-0.70.6-0.5-0.2-0.1
Social responses0.20.31.8-0.4-0.8-0.8-0.10.1-0.30.4-1.3-0.40.4-0.4-0.2-0.30.60.3-0.50.50.80.70.60.80.4-0.60.20.1
Social time0.91.25.72.22.42.41.2-1.2-0.20.21.40.0-0.00.00.20.20.90.20.2-0.4-1.4-1.2-1.3-1.5-0.60.80.3-0.3
Soleus weight3.39.631.8-3.1-5.2-5.4-1.11.1-1.11.1-5.6-1.41.4-1.4-1.4-1.52.61.4-2.42.24.64.14.05.52.3-3.3-1.42.4
Bone: stiffness0.60.91.80.50.90.9-0.30.30.9-0.90.90.9-0.90.90.81.1-0.2-0.91.0-1.2-1.3-1.3-1.3-1.1-1.11.11.10.4
Tibialis anterior weight0.10.21.0-0.6-1.0-1.0-0.50.50.1-0.1-0.90.0-0.00.00.00.00.3-0.6-0.10.10.30.50.40.80.1-0.30.30.7
Time to tail flick, vehicle, before self-admin0.30.31.81.31.11.20.6-0.6-0.30.30.5-0.20.2-0.2-0.1-0.30.10.10.20.1-0.5-0.5-0.5-1.00.00.20.2-0.5
Time to tail flick, vehicle, after self-admin1.31.47.30.61.41.60.0-0.00.7-0.81.40.9-0.90.91.00.6-0.9-0.41.0-0.9-1.4-1.4-1.5-1.4-1.11.31.4-2.7
Time to tail flick, test, before self-admin2.82.76.2-1.1-2.0-2.10.2-0.2-1.31.3-2.1-1.51.5-1.5-1.6-1.71.41.5-1.61.72.52.22.22.41.7-2.0-1.10.1
Time to tail flick, test, after self-admin2.52.66.5-1.2-2.1-2.20.1-0.1-1.21.2-1.8-1.51.5-1.5-1.2-1.10.81.2-1.51.52.22.22.22.11.6-1.9-0.72.5
Delta time to tail flick, vehicle, before/after SA0.40.46.90.20.90.90.4-0.40.1-0.10.90.2-0.20.20.10.2-0.20.10.1-0.2-0.5-0.5-0.5-0.4-0.40.50.2-2.6
Delta time to tail flick, test, before/after SA0.40.42.4-0.8-0.7-0.6-0.70.70.6-0.6-0.30.4-0.40.40.70.5-1.1-0.40.4-0.4-0.0-0.1-0.1-0.2-0.30.31.01.6
Tibia length2.36.513.81.12.83.0-0.60.62.0-2.13.32.2-2.22.22.22.4-1.8-2.02.6-2.8-3.7-3.5-3.5-3.7-2.93.22.4-0.8
Ambulatory time before self-admin4.54.78.7-1.8-0.9-0.7-2.52.52.7-2.70.52.7-2.72.72.62.9-2.9-2.62.5-2.4-1.6-1.8-1.7-1.1-2.01.92.1-0.4
Ambulatory time after self-admin0.30.43.3-0.6-0.6-0.6-0.70.70.7-0.70.40.6-0.60.60.70.6-1.8-0.50.5-0.5-0.1-0.2-0.1-0.1-0.10.10.20.2
Bone: tissue strength0.10.10.3-0.10.10.1-0.30.30.3-0.30.30.3-0.30.30.10.5-0.4-0.20.4-0.2-0.2-0.3-0.3-0.3-0.30.30.1-0.1
Total heroin consumption0.40.52.6-0.8-1.1-1.2-0.20.2-0.20.30.1-0.20.2-0.2-0.30.1-0.10.1-0.20.30.80.80.90.80.9-0.9-0.71.6
Bone: trabecular number1.32.07.8-1.7-2.7-2.8-0.80.8-0.20.3-2.2-0.40.4-0.4-0.3-0.50.60.9-0.90.82.21.81.92.41.0-1.4-0.31.4
Bone: trabecular spacing3.14.110.00.72.22.3-0.50.51.6-1.72.61.7-1.71.71.61.6-1.8-2.02.1-2.1-3.0-2.7-2.7-3.2-2.22.51.6-0.3
Bone: trabecular thickness3.03.66.41.0-0.2-0.41.8-1.8-2.22.1-1.0-2.12.1-2.1-2.1-2.31.82.5-2.22.12.22.02.01.92.2-2.1-2.00.2
Bone: trabecular tissue density1.11.54.42.11.61.61.8-1.8-1.41.4-0.3-1.21.2-1.2-1.3-1.32.01.4-1.11.00.30.30.2-0.20.7-0.5-1.0-0.3
Water consumed over 24 hours1.01.12.6-0.9-0.1-0.0-1.21.21.2-1.20.51.1-1.11.11.21.3-1.3-1.61.3-1.0-1.2-1.0-1.0-0.8-1.01.00.8-1.2
Number of responses in last shaping day0.80.92.5-0.8-0.1-0.0-0.90.91.0-1.00.51.0-1.01.00.81.0-1.6-1.01.1-0.8-0.7-0.8-0.8-1.1-0.70.81.1-0.9