Hub : Genes

Plce1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_063262818.1 0.02 0.01 5.1e-03 0.01 0.01 0.01 0 1.8e-02 2.0e-02 3.2e-02 1.2e-01
2 Liver isoform ratio XM_039108292.2 0.06 0.03 2.5e-05 0.02 0.03 0.02 0.02 2.8e-03 1.6e-04 1.7e-03 1.1e-03
3 Brain intron excision ratio chr1_245898706_245901140 0.02 0.02 4.4e-03 0.02 0.02 0.02 0.02 5.2e-03 4.7e-03 5.3e-03 4.3e-03
4 Brain intron excision ratio chr1_245898484_245898570 0.02 0.02 6.7e-03 0.02 0.02 0.01 0.02 2.8e-03 8.3e-03 7.8e-02 1.1e-02
5 Liver isoform ratio XM_063262818.1 0.11 0.06 3.4e-08 0.02 0.05 0.03 0.03 4.7e-03 6.1e-06 4.3e-04 5.3e-04
6 Adipose gene expression Plce1 0.09 0.06 7.8e-06 0.02 0.04 0.04 0.04 1.3e-03 1.8e-05 2.3e-05 1.3e-05
7 Liver alternative TSS XM_063262818.1 0.14 0.07 2.0e-09 0.03 0.06 0.04 0.04 9.3e-05 3.0e-07 1.9e-05 5.1e-05
8 Liver alternative TSS XM_039108292.2 0.16 0.09 9.1e-11 0.05 0.07 0.06 0.05 3.2e-06 3.3e-08 5.6e-07 1.5e-06
9 Liver alternative TSS XM_063262818.1 0.15 0.08 5.7e-10 0.04 0.06 0.05 0.05 8.0e-06 1.4e-07 2.9e-06 3.3e-06
10 PL gene expression Plce1 0.09 0.06 6.4e-05 0.05 0.04 0.03 0.05 3.7e-06 1.5e-05 1.3e-04 5.2e-06
11 BLA alternative TSS NM_053758.2 0.09 0.05 1.3e-03 0.05 0.06 0.05 0.05 1.1e-03 7.0e-04 1.8e-03 1.8e-03
12 NAcc alternative TSS XM_063262818.1 0.02 0.01 4.0e-03 0 0.01 0.01 0 5.0e-02 1.5e-02 2.2e-02 2.8e-01
13 Liver alternative TSS NM_053758.2 0.22 0.14 1.0e-03 0.02 0.01 0.02 0.02 1.9e-03 3.9e-02 3.3e-03 8.7e-04
14 BLA alternative TSS XM_039108292.2 0.16 0.09 3.3e-05 0.1 0.08 0.07 0.08 6.1e-06 3.6e-05 8.8e-05 4.2e-05
15 BLA gene expression Plce1 0.09 0.06 9.3e-04 0.07 0.06 0.05 0.06 1.5e-04 4.6e-04 1.4e-03 3.2e-04
16 Brain gene expression Plce1 0.06 0.04 4.8e-03 0.02 0.02 0.02 0.02 8.8e-03 4.1e-03 2.3e-03 7.3e-03
17 IC mRNA stability Plce1 0.14 0.09 3.4e-03 0.03 0.06 0 0.04 1.4e-02 1.1e-03 1.9e-01 6.6e-03
18 BLA isoform ratio XM_039108292.2 0.11 0.08 3.3e-03 0.02 0.05 0.03 0.02 2.1e-02 1.2e-03 1.0e-02 3.2e-02
19 Liver mRNA stability Plce1 0.43 0.13 2.6e-12 0.09 0.1 0.07 0.09 1.9e-10 6.6e-11 4.5e-08 4.9e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.83.16.5-2.02.2-2.62.6-2.02.2-1.91.8-1.81.4-1.3-0.71.21.51.52.1-1.30.4-1.2
Area under the delay curve1.01.12.91.4-1.10.6-0.61.1-0.21.1-1.11.1-1.21.41.7-1.2-1.0-1.0-0.2-1.1-1.30.5
BMI with tail0.20.92.7-0.31.1-0.70.7-1.11.7-1.21.2-1.21.1-0.5-0.00.80.70.71.0-1.1-0.4-0.6
BMI without tail0.00.10.4-0.20.10.5-0.5-0.1-0.2-0.20.2-0.20.7-0.2-0.20.00.00.0-0.20.0-0.00.2
Body weight0.31.13.6-1.41.0-0.10.1-1.0-0.7-1.01.1-1.01.9-1.3-1.41.21.21.20.31.01.1-0.3
Weight adjusted by age0.30.51.61.10.20.1-0.1-0.41.2-0.60.5-0.5-0.4-0.00.80.2-0.5-0.51.3-0.9-0.2-1.2
Bone surface1.83.36.0-2.32.3-2.42.4-2.11.8-2.12.0-2.02.0-1.5-1.11.61.61.61.9-1.00.6-1.1
Bone volume2.34.16.0-2.12.5-2.42.4-2.41.6-2.32.3-2.32.1-2.0-1.51.91.91.92.3-0.41.2-1.6
Breakpoint value in progressive ratio session0.80.92.60.5-0.80.2-0.21.0-1.41.1-1.11.1-0.71.00.7-1.1-1.1-1.1-1.2-0.5-0.91.6
Number of licking bursts1.42.35.41.7-1.60.9-0.91.6-0.21.5-1.61.5-2.02.02.3-1.6-1.7-1.7-0.4-1.3-1.80.6
Context. condit. distance diff. score0.91.02.1-1.41.2-1.41.4-1.10.9-1.01.1-1.00.9-0.9-0.91.01.01.00.8-0.10.4-0.6
Locomotion velocity, session 12.72.96.21.2-2.00.9-0.92.0-0.82.0-2.12.1-2.52.12.1-2.0-1.5-1.5-1.3-0.8-1.61.1
Locomotion distance, session 11.01.33.01.0-1.40.7-0.71.3-0.71.3-1.31.3-1.71.41.5-1.4-1.0-1.0-0.6-0.5-1.20.6
Locomotion velocity, session 21.31.55.3-0.8-0.1-1.11.10.70.40.9-1.01.0-1.51.41.2-1.4-0.9-0.9-0.8-2.3-2.01.8
Locomotion distance, session 20.60.92.50.2-0.6-0.30.30.8-0.50.8-0.90.9-1.11.21.1-1.3-0.7-0.7-0.7-1.3-1.61.2
Locomotion velocity, session 30.10.20.6-0.80.5-0.70.7-0.4-0.2-0.30.3-0.30.0-0.3-0.50.30.50.50.2-0.10.20.1
Locomotion distance, session 31.01.13.2-1.40.8-0.40.4-0.8-0.4-0.70.8-0.81.0-1.3-1.81.01.21.20.31.61.6-0.6
Stereotopy head waving bouts, day 30.20.20.80.10.0-0.40.4-0.10.9-0.10.0-0.1-0.20.20.70.2-0.2-0.20.8-0.7-0.2-0.8
Stereotopy head waving duration, day 30.40.51.90.6-0.1-0.50.50.11.20.0-0.10.1-0.80.71.2-0.1-0.5-0.50.8-1.4-0.9-0.6
Locomotion velocity, session 73.03.24.7-2.01.9-1.81.8-2.01.1-1.91.9-1.91.5-1.8-1.62.12.22.21.90.51.3-1.8
Locomotion distance, session 72.22.84.3-2.11.9-1.71.7-1.80.6-1.81.8-1.81.6-1.9-1.91.92.02.01.30.71.4-1.2
Stereotopy head waving bouts, day 70.91.02.00.1-0.90.1-0.11.00.81.2-1.21.2-1.11.21.3-1.0-1.4-1.4-0.5-0.8-0.80.5
Stereotopy head waving duration, day 70.20.20.8-0.1-0.5-0.00.00.50.90.6-0.60.6-0.40.50.6-0.2-0.6-0.6-0.1-0.2-0.1-0.2
Locomotion velocity, session 80.10.20.5-0.70.2-0.70.7-0.10.5-0.00.00.0-0.50.20.1-0.00.10.10.0-0.6-0.60.2
Locomotion distance, session 80.40.62.7-0.70.5-1.51.5-0.20.9-0.20.1-0.1-0.30.40.5-0.4-0.2-0.20.2-1.6-1.30.7
Degree of sensitization distance0.20.21.5-0.10.2-0.60.60.00.4-0.0-0.00.0-0.40.50.7-0.1-0.3-0.30.1-1.2-1.00.3
Degree of sensitization stereotypy1.41.52.80.1-1.30.7-0.71.40.21.6-1.61.6-1.21.41.2-1.4-1.7-1.7-1.3-0.4-0.91.3
Conditioned locomotion1.41.62.80.10.9-0.20.2-1.20.2-1.31.3-1.31.5-1.5-1.31.51.71.71.11.31.6-1.6
Cocaine response after cond. corrected0.20.20.70.4-0.40.3-0.30.5-0.20.5-0.50.5-0.40.70.4-0.2-0.4-0.4-0.6-0.5-0.80.6
Cocaine response after cond. not corrected0.30.40.90.1-0.40.2-0.20.6-0.30.6-0.70.7-0.70.80.5-0.3-0.6-0.6-0.7-0.7-1.01.0
Cocaine response before conditioning0.30.30.9-0.2-0.50.2-0.20.6-0.40.7-0.70.7-0.90.70.6-0.6-0.6-0.6-0.4-0.4-0.60.7
Saline control response2.43.24.51.9-2.01.5-1.52.0-1.72.0-2.12.0-1.71.71.7-2.1-2.0-2.0-2.0-0.1-1.11.7
Bone: connectivity density2.84.48.3-2.32.6-2.92.9-2.42.7-2.32.2-2.22.0-1.6-0.91.61.81.82.3-1.50.6-1.3
Bone: cortical apparent density0.91.32.41.0-1.20.6-0.61.20.81.2-1.21.2-1.41.31.5-1.2-1.6-1.6-0.7-0.7-1.10.5
Bone: cortical area1.21.83.9-1.81.3-0.80.8-1.3-0.8-1.21.3-1.31.8-1.8-2.01.51.21.20.51.51.9-0.7
Bone: cortical porosity0.80.84.1-0.90.6-1.41.4-0.41.5-0.40.3-0.3-0.20.50.7-0.20.20.20.8-2.0-1.40.1
Bone: cortical porosity0.60.62.1-1.40.8-1.41.4-0.51.1-0.50.4-0.40.10.10.10.10.40.40.6-1.5-0.80.2
Bone: cortical thickness0.71.24.70.7-1.21.5-1.51.0-2.21.1-1.01.0-0.60.3-0.1-0.5-0.9-0.9-1.31.60.50.6
Bone: cortical thickness1.92.23.61.2-1.91.5-1.51.8-1.41.8-1.71.7-1.71.61.4-1.7-1.6-1.6-1.40.2-0.91.0
Bone: cortical tissue density1.01.32.61.0-1.20.5-0.51.21.01.1-1.21.2-1.51.41.6-1.2-1.6-1.6-0.6-0.9-1.20.5
Condit. Reinf. active minus inactive responses0.10.10.5-0.4-0.3-0.10.10.4-0.70.5-0.40.5-0.50.3-0.1-0.4-0.1-0.1-0.50.3-0.00.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.1-0.30.1-0.10.3-0.40.4-0.40.4-0.00.1-0.3-0.3-0.1-0.1-0.70.50.20.4
Condit. Reinf. active responses0.10.11.0-0.4-0.20.1-0.10.2-1.00.3-0.20.2-0.30.0-0.4-0.10.20.2-0.40.70.20.1
Condit. Reinf. inactive responses0.00.00.40.1-0.20.1-0.10.1-0.60.1-0.00.1-0.50.20.1-0.10.10.1-0.00.1-0.2-0.1
Incentive salience index mean0.60.72.30.2-0.90.8-0.80.9-1.51.0-0.90.9-0.90.60.1-0.9-0.6-0.6-1.10.5-0.21.0
Condit. Reinf. lever presses1.31.83.51.3-1.61.8-1.81.5-1.91.4-1.41.4-1.41.10.6-1.2-1.2-1.2-1.40.6-0.51.2
Condit. Reinf. active minus inactive responses2.83.64.9-1.52.1-1.81.8-2.21.7-2.22.2-2.22.1-1.9-1.32.02.12.12.2-0.11.3-1.9
Condit. Reinf. active-inactive response ratio1.72.04.0-0.81.5-1.41.4-1.62.0-1.71.6-1.61.5-1.2-0.61.41.51.51.7-0.60.5-1.5
Condit. Reinf. active responses1.41.93.1-0.71.2-0.50.5-1.50.2-1.51.6-1.61.8-1.7-1.41.71.71.71.31.11.7-1.6
Condit. Reinf. inactive responses0.70.94.40.4-0.71.4-1.40.5-2.10.5-0.40.40.1-0.3-0.80.10.00.0-0.72.01.10.1
Condit. Reinf. lever presses0.20.30.70.8-0.60.5-0.50.6-0.60.6-0.60.6-0.20.40.5-0.7-0.2-0.2-0.60.1-0.20.4
Condit. Reinf. lever reinforcers received0.71.01.7-0.30.8-0.30.3-1.0-0.0-1.11.1-1.11.3-1.2-1.01.11.31.31.00.81.2-1.2
Conditioned reinforcement - actives0.40.63.0-1.0-0.2-0.30.30.60.10.8-0.80.9-0.70.60.2-0.9-0.7-0.7-1.2-0.6-0.71.7
Conditioned reinforcement - inactives0.60.85.3-2.30.3-1.21.20.21.20.5-0.50.5-1.10.60.1-0.1-0.5-0.5-0.5-1.1-0.90.9
Conditioned locomotion0.10.20.5-0.6-0.30.3-0.30.40.00.5-0.50.5-0.50.2-0.1-0.4-0.4-0.4-0.70.40.20.5
Patch foraging indifference point 0 sec0.40.83.41.0-0.91.0-1.00.9-1.80.9-0.90.9-0.30.30.0-0.7-0.5-0.5-1.01.00.40.7
Patch foraging indifference point AUC4.26.08.52.0-2.82.3-2.32.8-2.52.9-2.92.9-2.62.52.0-2.7-2.5-2.5-2.70.1-1.62.3
Delay disc. indifference point, 0s delay0.70.72.70.00.9-1.11.1-0.81.6-0.70.6-0.70.2-0.20.4-0.10.90.91.2-1.5-0.3-0.4
Delay disc. indifference point, 16s delay1.21.32.40.7-1.11.0-1.01.2-0.81.2-1.31.3-1.01.41.3-1.3-1.5-1.5-0.8-0.8-1.31.1
Delay disc. indifference point, 2s delay0.30.41.51.0-0.1-0.50.50.10.9-0.0-0.10.00.20.51.2-0.4-0.2-0.20.8-1.1-0.7-0.6
Delay disc. indifference point, 24s delay2.02.33.20.8-1.71.3-1.31.7-1.31.8-1.81.8-1.61.71.4-1.5-1.7-1.7-1.5-0.4-1.31.3
Delay disc. indifference point, 4s delay1.41.43.21.3-1.00.5-0.51.1-0.01.1-1.21.1-1.41.51.8-1.6-1.1-1.1-0.5-1.6-1.61.1
Delay disc. indifference point, 8s delay1.92.26.12.5-1.81.5-1.51.7-0.91.6-1.71.6-1.81.82.1-1.5-1.2-1.2-0.4-0.5-1.20.2
Indifference point function ln k3.66.38.4-2.32.9-2.52.5-2.92.0-2.92.9-2.92.9-2.6-2.32.82.72.72.50.11.7-2.2
Indifference point function log k3.66.38.4-2.32.9-2.52.5-2.92.0-2.92.9-2.92.9-2.6-2.32.82.72.72.50.11.7-2.2
Patch foraging total patch changes 0 sec0.40.73.51.1-0.91.1-1.10.8-1.90.9-0.80.8-0.20.2-0.1-0.6-0.5-0.5-0.91.20.60.6
Patch foraging total patch changes 12 sec4.96.38.82.8-3.02.5-2.52.9-2.12.9-2.92.9-3.02.42.1-2.8-2.7-2.7-2.50.2-1.31.9
Patch foraging total patch changes 18 sec1.32.03.31.8-1.61.0-1.01.6-1.21.6-1.71.7-1.41.51.5-1.8-1.4-1.4-1.3-0.3-0.91.1
Patch foraging total patch changes 24 sec0.61.04.51.0-1.11.0-1.01.1-2.11.2-1.11.1-0.70.50.1-1.1-0.4-0.4-1.31.00.21.0
Patch foraging total patch changes 6 sec4.26.49.72.1-3.02.5-2.53.0-2.93.1-3.13.1-2.52.31.6-2.8-2.2-2.2-2.90.7-1.12.5
Patch foraging time to switch 0 sec0.71.42.91.2-1.21.1-1.11.20.11.1-1.11.1-1.31.51.7-1.1-1.3-1.3-0.5-1.1-1.50.5
Patch foraging water rate 0 sec0.81.72.9-1.31.5-1.51.5-1.50.4-1.31.3-1.31.3-1.6-1.71.31.41.40.90.71.5-0.7
Patch foraging water rate 12 sec0.40.92.4-1.21.0-1.01.0-0.9-0.4-0.80.8-0.80.7-1.2-1.50.81.11.10.20.91.3-0.2
Patch foraging water rate 18 sec0.81.32.8-1.71.3-1.51.5-1.20.3-1.01.1-1.01.3-1.2-1.41.11.21.20.50.30.9-0.2
Patch foraging water rate 24 sec0.60.81.2-0.81.1-0.90.9-1.00.0-1.01.0-1.00.9-1.0-1.01.11.11.10.60.20.7-0.5
Patch foraging water rate 6 sec0.10.10.4-0.30.4-0.30.3-0.40.1-0.40.4-0.40.3-0.4-0.40.60.30.30.20.00.2-0.2
Seeking ratio, delayed vs. immediate footshock0.20.31.10.1-0.30.7-0.70.2-0.60.3-0.30.30.8-0.2-0.5-0.1-0.5-0.5-0.71.00.70.3
Distance traveled before self-admin0.20.31.2-0.80.7-1.11.1-0.40.4-0.20.2-0.20.8-0.1-0.2-0.20.50.5-0.0-0.7-0.20.6
Distance traveled after self-admin0.91.13.2-1.11.2-1.71.7-0.91.8-0.90.8-0.81.0-0.30.30.10.20.21.3-1.7-0.4-0.2
Extensor digitorum longus weight0.31.22.9-1.31.1-1.11.1-1.10.1-1.11.1-1.11.7-1.2-1.21.01.31.30.60.71.0-0.7
Bone: elastic displacement0.40.42.20.50.1-0.10.1-0.41.5-0.50.4-0.5-0.1-0.10.60.10.60.61.1-0.50.2-1.5
Bone: elastic work0.50.63.1-0.30.7-0.90.9-0.71.7-0.80.7-0.70.0-0.20.50.40.50.51.3-1.0-0.0-1.1
Bone: endosteal estimation3.57.715.7-4.03.5-3.43.4-3.21.8-3.13.0-3.02.9-2.6-2.42.42.82.82.6-0.61.4-1.5
Bone: endosteal perimeter3.16.611.1-3.13.3-3.23.2-3.11.7-3.03.0-2.93.0-2.5-2.12.32.42.42.3-0.81.2-1.3
Epididymis fat weight1.55.18.4-1.02.2-1.01.0-2.61.7-2.72.7-2.82.6-2.5-1.72.52.62.62.90.72.0-2.9
Delta time in closed arm before/after self-admin0.40.31.60.1-0.30.9-0.90.1-1.20.1-0.00.0-0.2-0.3-0.60.50.20.20.01.30.7-0.5
Delta time in open arm before/after self-admin1.01.06.5-0.40.6-1.41.4-0.21.4-0.20.0-0.0-0.30.60.9-0.7-0.7-0.70.0-2.5-1.61.2
Diff in mean of infusions in LGA sessions0.91.12.9-1.71.3-1.41.4-1.10.6-1.01.0-1.00.6-0.9-0.90.91.31.30.9-0.30.5-0.4
Delay discount exponential model param1.21.33.0-1.31.1-0.60.6-1.20.3-1.21.2-1.21.3-1.5-1.71.31.11.10.41.11.4-0.6
Extinction: sum of active levers before priming0.30.32.2-1.20.10.3-0.3-0.1-1.50.00.1-0.00.5-0.4-0.80.30.10.1-0.40.90.50.5
Active lever presses in extinction session 61.81.87.9-0.91.4-2.32.3-1.01.9-1.00.9-0.80.30.20.70.30.10.11.5-2.8-1.60.0
Bone: final force0.10.21.4-1.20.3-0.00.0-0.1-1.1-0.10.1-0.10.6-0.3-0.60.50.10.1-0.50.30.10.7
Bone: final moment0.20.31.3-1.20.4-0.00.0-0.4-1.0-0.30.4-0.40.9-0.5-0.80.70.50.5-0.10.50.50.2
Food consumed during 24 hour testing period0.20.30.7-0.6-0.50.6-0.60.5-0.90.6-0.60.6-0.50.3-0.2-0.1-0.2-0.2-0.70.70.10.3
Glucose0.20.41.4-0.60.5-0.10.1-0.5-0.5-0.40.5-0.40.5-0.8-1.20.60.80.8-0.20.90.8-0.0
Heart weight0.91.46.2-0.60.20.9-0.9-0.5-1.1-0.50.6-0.71.5-1.4-1.71.01.21.2-0.02.52.1-1.0
Delay discount hyperbolic model param0.80.92.5-1.30.9-0.50.5-1.00.1-0.91.0-1.01.0-1.3-1.61.10.90.90.11.11.2-0.4
Intermittent access intake day 1-15 change0.71.43.8-2.01.6-1.61.6-1.20.7-1.01.0-1.01.6-1.1-1.41.01.31.30.1-0.20.60.4
Intermittent access intake escalation1.02.14.8-2.21.9-2.12.1-1.51.1-1.41.3-1.31.8-1.4-1.51.21.51.50.5-0.30.80.2
Intermittent access intake escalation 22.12.46.8-2.22.1-2.62.6-1.61.4-1.41.3-1.31.6-1.2-1.31.01.61.60.5-0.90.40.4
Intermitt. access day 1 inactive lever presses0.00.21.20.10.3-0.60.6-0.31.1-0.30.2-0.2-0.10.10.30.20.00.00.5-0.8-0.3-0.3
Intermitt. access day 15 inactive lever presses0.51.02.7-1.60.9-0.80.8-1.01.4-0.90.9-0.90.3-1.0-0.90.60.90.91.20.41.1-1.3
Intermitt. access escalation Index0.71.02.10.30.7-0.80.8-0.91.0-0.91.0-1.00.7-1.1-1.01.01.21.20.70.81.3-1.5
Intermittent access day 1 total infusions0.20.31.9-1.40.3-0.50.5-0.21.2-0.10.1-0.1-0.40.10.10.1-0.3-0.30.3-0.6-0.3-0.1
Intermittent access day 15 total infusions1.31.97.6-2.71.7-1.51.5-1.41.3-1.21.3-1.21.3-1.4-1.81.41.11.10.30.31.1-0.1
Intermittent access terminal intake (last 3 days)1.01.36.5-2.51.4-1.61.6-1.11.6-0.90.9-0.80.7-0.9-1.31.00.90.90.3-0.10.6-0.0
Intermittent access total infusions0.60.73.8-1.90.9-0.90.9-0.81.3-0.60.7-0.60.3-0.6-0.90.80.50.50.50.10.5-0.4
Intermittent access day 1 locomotion0.20.31.4-1.20.6-0.20.2-0.51.1-0.60.6-0.50.4-0.3-0.30.5-0.2-0.20.4-0.4-0.1-0.3
Intermittent access day 15 total locomotion0.30.51.0-0.6-0.4-0.00.00.60.20.7-0.70.7-0.90.90.6-0.6-0.9-0.9-0.8-0.7-1.00.9
Intermittent access total locomotion0.30.41.5-1.20.2-0.50.50.01.00.1-0.10.1-0.40.60.6-0.3-0.6-0.60.1-1.2-1.10.3
Intermittent access standard deviation0.71.48.6-2.91.4-1.61.6-0.90.9-0.60.7-0.60.7-0.8-1.40.71.11.1-0.3-0.40.21.2
Left kidney weight0.10.51.8-0.5-0.51.0-1.00.5-1.30.6-0.50.50.1-0.1-0.6-0.40.00.0-1.11.40.60.6
Right kidney weight0.41.75.90.1-1.42.1-2.11.2-2.41.3-1.11.2-0.40.3-0.4-0.7-0.5-0.5-1.72.00.60.9
Cocaine induced anxiety1.21.72.7-0.11.5-1.51.5-1.51.7-1.51.5-1.51.3-1.1-0.61.21.11.11.6-0.60.5-1.5
Post-drug Anxiety1.41.54.00.90.8-0.10.1-1.20.1-1.31.3-1.41.5-1.4-1.01.41.51.51.31.11.4-2.0
Baseline Anxiety0.70.83.70.5-0.61.4-1.40.3-1.90.2-0.10.10.2-0.4-0.60.30.30.3-0.31.91.0-0.4
Tail length0.20.93.6-0.90.30.2-0.2-0.3-1.9-0.20.3-0.21.0-1.1-1.40.60.60.6-0.41.81.70.1
Length with tail0.20.94.2-1.3-0.10.3-0.30.1-2.10.3-0.20.20.7-0.7-1.30.40.40.4-1.01.91.40.6
Length without tail0.10.43.1-1.80.5-0.80.8-0.4-0.5-0.30.4-0.30.6-0.5-0.80.70.60.6-0.00.40.30.2
Times rat made contact with spout0.20.31.40.10.2-1.01.0-0.20.6-0.10.1-0.1-0.40.30.7-0.2-0.3-0.30.7-1.2-0.5-0.3
Lifetime Intake0.40.43.0-1.70.7-0.60.6-0.61.3-0.50.5-0.50.2-0.4-0.50.60.20.20.5-0.00.3-0.4
Liver weight, left0.20.31.7-0.1-0.30.8-0.80.2-1.30.2-0.10.20.5-0.2-0.70.20.20.2-0.91.10.50.4
Liver weight, right0.30.61.1-1.00.9-0.70.7-0.90.1-0.80.8-0.81.1-0.9-0.90.90.90.90.50.20.6-0.2
Locomotor activity0.00.10.2-0.20.3-0.30.3-0.20.5-0.20.1-0.10.3-0.2-0.0-0.00.10.10.2-0.10.4-0.2
Locomotor testing distance0.00.10.40.1-0.0-0.30.30.10.30.3-0.30.3-0.30.00.2-0.6-0.3-0.3-0.2-0.20.20.4
Locomotor testing rearing0.20.41.7-0.90.9-1.31.3-0.60.9-0.50.4-0.40.5-0.5-0.3-0.20.30.30.2-0.60.20.4
Locomotion in novel chamber2.22.96.9-1.82.2-2.02.0-2.02.6-2.02.0-1.91.4-1.1-0.61.31.11.12.0-1.6-0.1-1.0
Locomotion in novel chamber post-restriction0.50.92.7-0.5-0.60.6-0.60.8-0.60.8-0.80.8-0.61.00.7-1.0-1.4-1.4-0.9-0.6-1.31.7
Fecal boli incidents, locomotor time 10.30.51.7-0.70.7-1.31.3-0.61.2-0.50.5-0.50.5-0.20.00.5-0.1-0.11.0-0.6-0.1-0.7
Change in fecal boli incidents, locomotor task0.90.92.00.7-0.91.4-1.40.9-1.30.9-0.90.9-1.00.50.2-1.0-0.7-0.7-1.30.4-0.21.2
Time >=10cm from walls, locomotor time 10.91.03.6-1.7-0.10.3-0.30.4-1.90.7-0.50.6-0.1-0.2-1.4-0.10.00.0-1.91.20.41.8
Bouts of movement, locomotor time 10.20.30.70.5-0.70.3-0.30.6-0.20.6-0.60.6-0.60.70.9-0.7-0.5-0.50.0-0.3-0.5-0.2
Total resting periods, locomotor time 10.70.81.50.6-1.00.4-0.41.0-0.31.0-1.01.1-1.11.21.2-1.2-0.9-0.9-0.4-0.5-1.00.4
Rest time, locomotor task time 10.50.72.10.6-0.5-0.20.20.51.00.5-0.60.6-0.81.01.4-1.2-0.7-0.70.4-1.4-1.20.2
Distance moved, locomotor task time 10.50.72.9-0.6-0.01.0-1.00.0-1.70.00.0-0.00.1-0.8-1.40.30.50.5-1.01.61.20.7
Vertical activity count, locomotor time 10.20.52.0-0.0-0.10.8-0.80.1-1.40.1-0.00.00.6-0.5-1.10.40.20.2-1.11.30.70.6
Time >=10cm from walls, locomotor time 20.20.31.2-0.7-0.1-0.30.30.3-0.80.6-0.50.5-0.60.0-0.6-0.30.10.1-1.10.40.21.1
Bouts of movement, locomotor time 22.53.96.01.9-2.01.1-1.12.2-0.72.2-2.32.3-2.22.42.5-2.2-2.3-2.3-1.6-1.4-2.01.8
Total resting periods, locomotor time 22.54.46.31.9-2.11.1-1.12.3-0.92.4-2.52.4-2.32.52.5-2.4-2.4-2.4-1.7-1.5-2.12.1
Rest time, locomotor task time 21.41.84.01.4-1.20.3-0.31.3-0.41.3-1.41.4-1.31.61.8-2.0-1.6-1.6-0.7-1.3-1.81.3
Distance moved, locomotor task time 21.61.94.5-1.71.2-0.20.2-1.2-0.2-1.21.3-1.20.8-1.8-2.11.61.91.90.51.62.0-0.9
Vertical activity count, locomotor time 20.40.51.4-0.80.7-0.00.0-0.6-0.0-0.60.6-0.60.9-0.9-1.21.10.90.90.10.81.0-0.5
Light reinforcement 10.20.41.21.0-0.80.5-0.50.60.50.5-0.50.5-0.90.71.1-0.8-0.8-0.80.2-0.3-0.5-0.3
Light reinforcement 21.21.95.21.9-1.60.8-0.81.41.11.2-1.31.3-1.81.82.3-1.5-1.2-1.20.3-0.9-1.5-0.5
Bone: marrow area3.67.815.9-4.03.5-3.53.5-3.22.0-3.13.1-3.02.9-2.6-2.32.52.82.82.6-0.71.3-1.5
Bone: maximum diameter4.37.912.0-3.43.5-3.43.4-3.31.9-3.23.2-3.13.3-3.0-2.52.72.52.52.5-0.11.9-1.8
Bone: maximum force0.40.74.2-2.01.0-1.01.0-0.80.3-0.70.8-0.70.7-0.6-0.60.80.40.40.5-0.50.00.1
Bone: maximum moment0.50.94.0-2.01.1-1.01.0-1.10.2-1.01.0-1.01.0-0.8-0.81.00.90.90.8-0.20.4-0.4
Mean time between licks in bursts0.20.53.10.2-0.10.8-0.8-0.0-1.1-0.00.1-0.10.6-0.8-1.10.40.30.3-0.51.81.4-0.2
Mean num. licks in bursts1.82.74.0-1.82.0-1.71.7-1.90.8-1.81.9-1.81.9-1.9-2.01.71.71.71.10.51.4-0.9
Cd content in liver0.70.81.60.8-1.21.3-1.31.0-0.81.1-1.01.0-0.70.60.3-0.9-0.7-0.7-0.91.00.20.1
Co content in liver1.11.38.00.9-0.71.4-1.40.2-1.30.1-0.0-0.00.7-0.9-1.00.50.40.4-0.12.82.2-1.5
Cu content in liver5.66.79.02.7-2.92.0-2.03.0-1.12.9-3.02.9-2.73.02.9-3.0-2.8-2.8-2.3-1.1-2.42.1
Fe content in liver2.12.53.61.6-1.91.9-1.91.9-1.11.9-1.91.9-1.51.71.4-1.6-1.4-1.4-1.7-0.0-1.21.3
K content in liver1.71.64.40.5-0.7-0.00.01.10.01.1-1.21.2-1.21.61.5-1.4-1.4-1.4-1.1-1.8-2.11.9
Mg content in liver1.31.43.90.8-0.80.1-0.11.1-0.11.1-1.11.1-1.41.51.4-1.3-1.1-1.1-1.0-1.5-2.01.6
Mn content in liver5.05.511.92.1-2.10.9-0.92.30.32.2-2.32.3-2.93.13.2-2.4-2.8-2.8-1.4-2.5-3.41.9
Na content in liver2.02.24.00.7-1.40.9-0.91.6-0.31.6-1.61.6-1.41.91.6-1.7-1.7-1.7-1.4-1.1-2.01.6
Rb content in liver0.20.20.9-0.60.3-0.50.5-0.2-0.1-0.10.2-0.20.0-0.4-0.60.30.90.90.00.50.5-0.1
Se content in liver19.423.030.85.3-5.54.7-4.75.5-2.85.4-5.55.4-5.15.55.0-5.0-5.0-5.0-4.3-1.3-4.33.6
Sr content in liver0.70.61.30.1-0.70.6-0.60.9-0.20.9-0.90.9-0.80.80.6-0.9-1.1-1.1-1.1-0.3-0.71.0
Zn content in liver2.32.53.71.5-1.81.3-1.31.9-0.71.8-1.91.8-1.61.91.8-1.8-1.6-1.6-1.4-0.8-1.61.3
Bone: minimum diameter6.211.421.2-4.64.0-3.33.3-3.91.3-3.73.7-3.73.9-3.9-3.93.53.33.32.41.03.1-1.9
Time in familiar zone, hab. session 10.50.51.7-0.00.5-0.30.3-0.61.3-0.80.7-0.70.8-0.30.40.70.40.41.2-0.6-0.0-1.2
Time in novel zone, hab. session 10.70.71.70.3-0.70.4-0.40.9-0.91.0-1.01.0-1.20.70.3-1.1-1.0-1.0-1.2-0.0-0.41.3
Total zone transitions, hab. session 10.30.41.20.1-0.3-0.20.20.50.10.5-0.60.6-1.00.80.8-0.9-0.7-0.7-0.3-1.0-1.10.9
Total locomotion distance, hab. session 11.41.93.71.5-1.61.1-1.11.5-0.81.5-1.51.5-1.91.81.8-1.5-1.3-1.3-0.7-0.8-1.60.9
Locomotion velocity, hab. session 12.23.15.41.9-2.11.6-1.62.0-1.32.0-2.01.9-2.32.12.0-1.9-1.6-1.6-1.1-0.5-1.71.1
Time in familiar zone, hab. session 20.40.52.00.7-0.10.5-0.5-0.3-0.2-0.30.4-0.40.4-0.7-0.40.30.40.40.61.41.4-1.4
Time in novel zone, hab. session 20.20.20.8-0.4-0.2-0.10.10.4-0.00.5-0.50.5-0.60.60.3-0.4-0.4-0.4-0.6-0.6-0.80.9
Total zone transitions, hab. session 20.60.81.70.6-1.00.7-0.71.0-1.00.9-0.90.9-1.30.80.7-1.2-0.9-0.9-0.70.1-0.60.8
Total locomotion distance, hab. session 20.60.81.90.8-1.31.2-1.21.0-1.30.9-0.90.9-1.40.80.8-0.8-0.6-0.6-0.40.6-0.3-0.0
Locomotion velocity, hab. session 20.91.22.51.2-1.41.2-1.21.2-1.21.1-1.11.1-1.61.21.2-1.1-0.9-0.9-0.50.1-0.80.4
Novel to familiar place preference ratio1.71.98.9-1.11.2-2.52.5-0.72.2-0.60.4-0.4-0.50.40.8-0.2-0.2-0.20.9-3.0-1.70.6
Novelty place preference1.82.09.4-1.11.3-2.62.6-0.72.3-0.60.4-0.4-0.50.40.8-0.2-0.2-0.20.9-3.1-1.70.6
Time in novel zone, NPP test1.81.98.4-1.21.3-2.62.6-0.82.2-0.70.5-0.5-0.50.30.7-0.1-0.1-0.11.0-2.9-1.50.5
Total zone transitions, NPP test0.50.82.40.7-1.11.1-1.11.0-1.51.0-0.90.9-1.10.70.4-0.9-0.5-0.5-0.90.5-0.40.7
Total locomotion distance, NPP test1.82.54.41.6-2.01.7-1.71.9-1.81.8-1.81.8-2.11.71.5-1.6-1.3-1.3-1.20.1-1.20.9
Locomotion velocity, NPP test1.82.53.81.5-1.91.7-1.71.8-1.91.8-1.81.8-1.91.71.4-1.6-1.3-1.3-1.30.1-1.21.1
Intraocular pressure0.10.20.60.7-0.60.7-0.70.40.00.3-0.30.2-0.50.40.8-0.4-0.3-0.30.4-0.1-0.2-0.5
Delta distance traveled before/after self-admin1.01.12.4-0.81.3-1.21.2-1.21.5-1.31.3-1.30.8-0.8-0.20.80.50.51.5-0.90.2-1.0
Delta ambulatory time before/after self-admin1.62.03.5-1.11.7-1.51.5-1.71.9-1.81.7-1.71.1-1.3-0.71.31.01.01.8-0.60.6-1.4
Parametrial fat weight0.41.03.70.5-0.91.4-1.40.8-1.90.8-0.70.70.4-0.0-0.5-0.1-0.2-0.2-1.51.80.90.4
Pavlov. Cond. lever latency0.10.21.00.50.2-0.10.1-0.30.5-0.40.4-0.40.6-0.4-0.10.30.10.10.50.30.6-1.0
Pavlov. Cond. magazine entry latency0.70.83.0-0.5-0.91.1-1.10.9-1.71.1-1.01.0-0.60.4-0.4-0.4-0.4-0.4-1.51.10.11.1
Pavlov. Cond. change in total contacts0.20.21.2-1.1-0.10.2-0.20.2-0.70.3-0.20.2-0.1-0.1-0.80.20.30.3-0.70.80.40.5
Pavlov. Cond. index score0.60.82.0-0.4-0.80.8-0.81.0-1.21.1-1.01.1-1.00.80.1-0.8-0.7-0.7-1.30.2-0.51.4
Pavlov. Cond. latency score0.50.61.7-0.4-0.70.7-0.70.8-1.20.9-0.90.9-0.90.60.1-0.7-0.5-0.5-1.10.2-0.41.3
Pavlov. Cond. lever contacts0.40.51.1-0.1-0.70.8-0.80.8-1.10.8-0.80.8-0.90.70.3-0.7-0.5-0.5-0.8-0.0-0.71.1
Pavlov. Cond. magazine entry number0.20.20.70.80.2-0.50.5-0.20.8-0.30.2-0.20.10.10.7-0.3-0.3-0.30.5-0.9-0.4-0.3
Pavlov. Cond. intertrial magazine entries0.00.00.30.1-0.20.2-0.20.1-0.50.1-0.10.1-0.10.10.1-0.00.30.3-0.00.2-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.0.60.71.7-0.3-0.80.8-0.80.9-1.11.0-1.01.0-1.00.70.1-0.7-0.7-0.7-1.20.2-0.51.3
Pavlov. Cond. response bias0.20.31.1-0.7-0.40.6-0.60.5-1.10.6-0.50.5-0.50.3-0.4-0.00.00.0-0.80.6-0.10.7
Pavlov. Cond. lever latency0.81.13.3-1.21.3-1.21.2-1.21.8-1.21.2-1.20.8-0.9-0.51.00.60.61.3-0.60.3-0.8
Pavlov. Cond. magazine entry latency0.20.31.5-0.3-0.40.4-0.40.3-1.20.4-0.30.3-0.50.1-0.50.50.60.6-0.60.90.4-0.1
Pavlov. Cond. change in total contacts0.30.42.60.7-0.70.9-0.90.6-1.60.6-0.60.6-0.20.3-0.0-0.3-0.0-0.0-0.80.70.20.4
Pavlov. Cond. index score0.50.73.40.5-1.00.9-0.91.0-1.91.0-1.01.0-0.70.60.1-0.5-0.1-0.1-1.20.8-0.00.6
Pavlov. Cond. latency score0.40.62.80.3-0.80.7-0.70.8-1.70.9-0.90.9-0.70.5-0.0-0.30.00.0-1.10.7-0.00.5
Pavlov. Cond. lever contacts0.91.24.11.3-1.41.3-1.31.2-2.01.3-1.21.2-0.70.80.5-0.9-0.5-0.5-1.30.9-0.10.7
Pavlov. Cond. magazine entry number1.11.45.5-0.61.4-1.51.5-1.32.3-1.41.3-1.31.2-0.80.00.30.10.11.5-1.3-0.1-0.6
Pavlov. Cond. intertrial magazine entries0.81.22.6-0.91.3-1.21.2-1.31.6-1.31.3-1.31.3-0.9-0.40.90.60.61.4-0.60.4-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.73.20.4-0.90.8-0.80.9-1.81.0-1.01.0-0.80.60.1-0.5-0.1-0.1-1.20.7-0.10.6
Pavlov. Cond. response bias0.81.14.31.0-1.31.2-1.21.2-2.11.2-1.21.1-0.70.70.2-0.6-0.3-0.3-1.31.00.00.6
Time in closed arm before self-admin0.30.41.7-0.40.6-1.21.2-0.51.3-0.40.4-0.40.1-0.10.40.10.10.10.9-0.9-0.1-0.6
Time in closed arm after self-admin0.10.20.60.8-0.20.3-0.3-0.1-0.6-0.10.1-0.10.1-0.20.20.30.20.20.60.50.5-0.8
Time in open arm before self-admin0.40.51.80.70.10.3-0.3-0.5-0.1-0.60.6-0.70.5-0.6-0.30.81.01.00.90.80.7-1.3
Time in open arm after self-admin0.60.72.90.3-0.1-0.40.40.40.40.4-0.50.5-0.70.91.0-1.0-0.9-0.9-0.5-1.7-1.41.2
Bone: periosteal estimation2.45.211.7-3.42.8-2.62.6-2.60.9-2.52.5-2.52.7-2.4-2.32.12.22.21.80.11.6-1.1
Bone: periosteal perimeter2.74.77.2-2.62.6-2.32.3-2.50.9-2.52.5-2.52.7-2.4-2.12.22.12.11.80.21.6-1.4
Bone: post-yield work0.71.04.1-2.01.3-1.31.3-1.10.2-1.11.1-1.00.8-0.9-0.91.10.80.80.9-0.40.3-0.3
Progressive ratio test 1 active lever presses0.20.31.0-1.0-0.0-0.20.20.20.70.3-0.30.3-0.30.50.4-0.4-0.7-0.7-0.2-0.7-0.70.6
Progressive ratio test 1 breakpoint0.30.30.7-0.9-0.2-0.00.00.40.50.4-0.40.5-0.40.60.5-0.6-0.8-0.8-0.4-0.7-0.80.8
Progressive ratio test 1 inactive lever presses0.30.52.7-1.60.7-1.11.1-0.51.4-0.40.4-0.4-0.4-0.2-0.00.30.10.10.7-0.8-0.1-0.3
Progressive ratio test 2 active lever presses0.60.74.2-2.00.8-1.41.4-0.51.2-0.30.3-0.3-0.4-0.1-0.20.30.00.00.5-1.0-0.30.0
Progressive ratio test 2 breakpoint0.60.74.4-2.10.8-1.51.5-0.61.2-0.40.3-0.3-0.4-0.1-0.20.30.10.10.5-0.9-0.2-0.1
Progressive ratio test 2 inactive lever presses0.40.62.9-1.40.5-1.11.1-0.21.7-0.10.1-0.0-0.80.30.4-0.1-0.3-0.30.6-1.4-0.70.0
Incentive Sensitization - Responses0.70.94.8-2.21.1-1.91.9-0.81.1-0.50.5-0.5-0.2-0.3-0.40.60.30.30.6-1.0-0.0-0.2
Incentive Sensitization - Breakpoint0.70.84.9-2.21.0-1.81.8-0.70.9-0.50.5-0.4-0.3-0.4-0.50.60.30.30.5-0.80.1-0.2
Sum of active levers in priming session hrs 5-60.10.10.20.5-0.30.5-0.50.2-0.40.1-0.10.10.00.10.3-0.00.10.10.20.10.1-0.3
Progressive ratio0.40.62.20.9-0.00.6-0.6-0.3-0.7-0.40.5-0.50.7-0.7-0.60.80.70.70.51.51.2-1.3
Food seeking constrained by brief footshock0.60.83.1-0.9-0.50.4-0.40.8-1.71.0-0.91.0-0.60.4-0.3-0.8-0.2-0.2-1.60.50.01.8
Seeking ratio, punishment vs. effort0.91.35.4-0.8-0.70.2-0.21.1-1.01.3-1.31.4-1.21.00.5-1.4-0.9-0.9-1.7-0.7-1.02.3
Retroperitoneal fat weight0.21.02.60.40.20.7-0.7-0.6-0.4-0.70.8-0.80.7-1.0-0.81.11.31.30.81.61.5-1.6
Reaction time number correct1.22.35.0-0.92.0-2.22.2-1.81.7-1.81.8-1.81.5-1.3-0.81.21.11.11.6-1.10.3-0.9
Reaction time mean minus median0.61.44.1-1.50.8-0.20.2-0.9-0.3-0.80.9-0.80.8-1.5-2.01.61.21.20.21.81.9-0.9
Reaction time mean minus median AUC0.51.43.4-0.80.8-0.20.2-0.9-0.2-0.91.0-1.01.0-1.4-1.81.71.41.40.51.71.8-1.3
Reaction time num false alarms0.20.21.8-0.1-0.10.5-0.50.1-1.30.1-0.10.10.4-0.3-0.5-0.1-0.1-0.1-0.60.90.60.4
Reaction time num false alarms AUC0.20.32.5-0.2-0.10.6-0.60.1-1.60.1-0.10.10.4-0.4-0.70.0-0.1-0.1-0.71.00.70.4
Reaction time trials correct on left1.22.35.0-0.92.0-2.22.2-1.81.7-1.81.8-1.81.5-1.3-0.81.21.11.11.6-1.10.3-0.9
Reaction time trials on left1.22.34.9-0.92.0-2.22.2-1.81.7-1.81.8-1.81.5-1.3-0.91.31.11.11.6-1.00.4-0.9
Reaction time mean0.50.94.5-0.4-0.71.4-1.40.5-1.60.6-0.50.5-0.1-0.3-1.00.40.20.2-0.82.11.3-0.2
Reaction time mean AUC0.60.93.6-0.1-0.91.6-1.60.7-1.70.8-0.70.7-0.3-0.0-0.70.2-0.0-0.0-1.11.91.00.1
Median of all reaction times0.60.83.1-0.1-0.91.5-1.50.7-1.50.8-0.70.7-0.30.1-0.50.0-0.1-0.1-0.91.80.9-0.1
Reaction time omissions1.62.35.3-1.21.1-0.50.5-1.30.1-1.21.3-1.31.3-1.9-2.31.91.71.70.62.22.3-1.7
Reaction time false alarm rate0.71.04.60.3-1.01.5-1.50.9-2.10.9-0.90.9-0.40.2-0.2-0.6-0.6-0.6-1.21.40.50.7
Reaction time premature initiation rate0.50.72.6-0.0-0.80.9-0.90.8-1.60.9-0.80.9-1.00.3-0.5-0.3-0.2-0.2-1.31.30.41.0
Reaction time premature initiations0.20.31.2-0.50.3-0.30.3-0.2-0.7-0.10.2-0.1-0.0-0.6-1.10.50.50.5-0.40.90.70.4
Std. dev. reaction times1.01.87.8-1.10.30.7-0.7-0.6-1.3-0.50.6-0.60.9-1.5-2.31.71.31.3-0.12.82.4-1.0
Reaction time trials completed1.22.34.9-0.92.0-2.22.2-1.81.7-1.81.8-1.81.5-1.3-0.91.31.11.11.6-1.00.4-0.9
Reaction time trials AUC1.12.14.6-0.71.9-2.12.1-1.71.6-1.81.7-1.71.4-1.2-0.71.21.01.01.5-1.00.3-0.9
Run reversals in cocaine runway, females0.70.72.00.6-0.80.3-0.30.8-0.30.8-0.90.8-1.01.11.4-0.9-0.8-0.8-0.1-1.1-1.10.4
Run reversals in cocaine runway, males2.72.74.31.4-2.01.7-1.72.0-2.02.0-2.02.0-1.41.50.9-1.7-1.3-1.3-2.10.7-0.81.7
Latency to leave start box in cocaine runway3.74.25.9-1.22.1-1.61.6-2.31.3-2.42.4-2.42.3-2.4-2.02.32.12.12.21.02.2-2.3
Latency to leave start box in cocaine runway, F3.64.15.7-1.52.3-2.02.0-2.41.6-2.42.4-2.42.3-2.3-1.82.02.12.12.00.31.8-1.7
Latency to leave start box in cocaine runway, M1.00.92.9-0.10.7-0.20.2-1.00.3-1.01.1-1.10.9-1.0-0.81.20.70.71.30.91.2-1.7
Std. dev. time between licks in bursts0.81.13.81.8-1.42.0-2.01.0-1.00.9-0.90.8-0.30.60.6-0.5-0.4-0.4-0.71.10.1-0.3
Total sessions with >9 infusions0.30.41.00.3-0.60.7-0.70.60.30.5-0.60.5-0.50.70.9-0.7-1.0-1.0-0.4-0.6-0.70.6
Short access day 1 total inactive lever presses1.52.010.3-0.91.3-1.81.8-1.33.2-1.41.3-1.30.5-0.40.60.70.30.32.0-1.9-0.5-1.4
Short access day 10 total inactive lever presses0.10.10.50.60.1-0.30.3-0.2-0.1-0.10.1-0.1-0.1-0.4-0.30.10.50.50.10.50.7-0.5
Short access day 1 total infusions0.60.81.70.4-0.90.7-0.70.80.80.8-0.80.8-1.31.11.3-0.9-1.3-1.3-0.1-0.8-1.10.2
Short access day 10 total infusions0.50.71.30.3-1.11.2-1.20.9-0.20.9-0.90.9-1.10.70.5-0.9-1.0-1.0-0.60.5-0.10.3
Short access total infusions0.20.21.2-0.7-0.1-0.10.10.21.10.2-0.20.2-0.60.40.5-0.4-0.6-0.60.2-0.6-0.50.1
Short access day 1 locomotion0.40.53.00.50.1-0.00.0-0.01.3-0.10.0-0.1-0.50.61.3-0.4-0.8-0.80.6-1.7-1.20.0
Short access day 10 total locomotion0.40.72.10.1-0.70.5-0.50.70.30.6-0.70.7-0.91.21.2-0.3-1.3-1.3-0.3-1.1-1.50.4
Short access total locomotion0.50.61.70.5-0.40.4-0.40.51.00.4-0.50.4-0.80.91.3-0.6-1.0-1.0-0.1-1.3-1.20.3
One hour access (0.3 mA shock)1.41.69.8-3.11.6-2.02.0-1.21.6-0.90.9-0.80.3-0.6-0.91.00.60.60.6-1.0-0.10.1
Compulsive drug intake1.51.72.5-1.21.4-1.41.4-1.41.2-1.31.4-1.40.9-1.6-1.61.51.51.50.70.61.5-1.1
One hour access (shock baseline)0.10.11.6-1.30.2-0.10.1-0.0-0.10.1-0.10.10.10.2-0.2-0.0-0.4-0.4-0.3-0.4-0.40.6
Social response proportion1.82.16.0-1.41.8-1.91.9-1.62.4-1.71.6-1.61.1-0.8-0.31.20.90.91.5-1.6-0.3-0.8
Social responses0.30.51.2-0.70.9-0.80.8-0.81.1-0.90.8-0.80.5-0.5-0.20.50.30.30.6-0.8-0.1-0.1
Social time0.50.62.20.5-0.60.7-0.70.7-0.80.7-0.70.7-0.30.70.5-1.0-0.8-0.8-1.2-0.5-0.91.5
Soleus weight1.44.15.6-2.02.3-2.02.0-2.31.2-2.32.3-2.32.2-2.0-1.62.42.22.22.10.11.3-2.0
Bone: stiffness0.50.84.9-2.21.1-1.11.1-0.9-0.1-0.80.8-0.80.9-0.8-1.10.80.40.40.3-0.00.40.3
Tibialis anterior weight0.51.62.8-1.71.5-1.71.7-1.40.7-1.41.4-1.31.5-1.2-0.91.31.21.21.1-0.30.5-0.6
Time to tail flick, vehicle, before self-admin1.31.34.41.5-0.90.2-0.20.91.00.7-0.90.8-0.91.52.1-1.4-1.2-1.20.2-1.8-1.70.2
Time to tail flick, vehicle, after self-admin0.10.20.8-0.20.5-0.70.7-0.4-0.9-0.30.3-0.30.1-0.2-0.1-0.20.40.40.1-0.6-0.20.5
Time to tail flick, test, before self-admin0.40.42.2-1.50.8-0.90.9-0.60.9-0.60.6-0.50.1-0.2-0.20.40.20.20.7-0.7-0.2-0.2
Time to tail flick, test, after self-admin0.30.31.00.90.0-0.50.5-0.10.8-0.10.0-0.1-0.30.30.90.10.20.20.8-1.0-0.3-0.7
Delta time to tail flick, vehicle, before/after SA0.70.71.5-1.21.0-1.01.0-0.9-1.0-0.70.8-0.70.5-0.9-1.20.81.01.00.10.20.60.3
Delta time to tail flick, test, before/after SA0.20.21.71.3-0.50.2-0.20.40.00.4-0.50.4-0.60.50.9-0.4-0.2-0.20.0-0.3-0.1-0.3
Tibia length0.10.31.20.2-0.40.6-0.60.3-1.00.4-0.30.3-0.0-0.2-0.50.0-0.3-0.3-0.71.10.70.3
Ambulatory time before self-admin0.20.31.1-0.60.6-1.01.0-0.30.5-0.20.1-0.10.9-0.1-0.0-0.20.30.30.0-0.7-0.20.5
Ambulatory time after self-admin1.92.36.7-1.71.8-2.52.5-1.42.6-1.41.2-1.21.3-0.60.10.50.60.61.6-2.1-0.5-0.3
Bone: tissue strength0.40.40.9-0.50.5-0.10.1-0.6-0.4-0.60.6-0.60.5-0.7-0.91.00.90.90.40.60.7-0.5
Total heroin consumption0.10.21.0-0.3-0.30.1-0.10.3-1.00.4-0.40.4-0.30.40.3-0.3-0.6-0.6-0.1-0.2-0.40.4
Bone: trabecular number1.42.24.1-1.91.8-2.02.0-1.72.0-1.61.5-1.51.3-1.1-0.71.11.41.41.7-0.90.5-1.0
Bone: trabecular spacing0.70.92.80.9-1.01.5-1.50.8-1.70.9-0.80.8-0.60.1-0.4-0.1-0.4-0.4-1.01.60.80.2
Bone: trabecular thickness1.72.13.1-1.61.8-1.71.7-1.71.0-1.61.6-1.61.4-1.5-1.31.21.51.51.3-0.11.1-1.0
Bone: trabecular tissue density0.40.61.6-1.01.0-1.31.3-0.90.9-0.90.9-0.90.6-0.8-0.50.40.40.40.6-0.30.3-0.3
Water consumed over 24 hours0.30.42.2-0.90.4-1.11.1-0.10.90.0-0.10.1-0.50.50.6-0.3-0.3-0.30.5-1.5-0.80.3
Number of responses in last shaping day0.10.11.20.6-0.20.5-0.5-0.01.1-0.10.1-0.1-0.3-0.00.3-0.0-0.1-0.10.10.00.2-0.7