Hub : Genes

Plce1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr1_236486086_236486172 0.02 0.02 6.0e-03 0.01 0.01 -0 0.01 4.1e-02 1.6e-02 4.9e-01 8.0e-02
2 Brain intron excision ratio chr1_236486308_236488744 0.02 0.02 4.5e-03 0.01 0.01 -0 0 3.2e-02 1.6e-02 5.0e-01 1.3e-01
3 Adipose gene expression Plce1 0.1 0.06 1.2e-05 0.02 0.04 0.03 0.04 3.3e-03 4.3e-05 2.2e-04 4.0e-05
4 BLA gene expression Plce1 0.1 0.06 2.0e-03 0.05 0.05 0.07 0.07 1.4e-03 7.8e-04 1.1e-04 1.9e-04
5 BLA alternative TSS XM_039108292.1 0.09 0.05 2.4e-04 0.04 0.07 0.05 0.04 2.4e-03 2.0e-04 1.7e-03 2.2e-03
6 BLA alternative TSS NM_053758.2 0.1 0.05 1.1e-04 0.06 0.07 0.05 0.06 6.7e-04 8.6e-05 7.6e-04 6.2e-04
7 Brain gene expression Plce1 0.06 0.04 8.1e-04 0.01 0 0.01 0 4.1e-02 9.4e-02 5.3e-02 1.2e-01
8 PL gene expression Plce1 0.08 0.05 6.2e-05 0.05 0.04 0.03 0.05 2.9e-06 2.2e-05 1.4e-04 5.4e-06
9 Liver mRNA stability Plce1 0.32 0.12 1.7e-10 0.08 0.08 0.07 0.07 3.2e-09 2.6e-09 2.1e-08 1.0e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.03.36.62.5-2.62.4-1.81.4-1.4-1.2-1.2-0.9
Area under the delay curve0.90.91.6-0.60.6-0.31.0-1.31.31.21.20.7
BMI with tail0.72.45.11.8-1.72.3-1.11.1-1.0-1.4-1.4-1.7
BMI without tail1.63.23.81.8-1.71.6-1.71.8-1.8-1.9-1.8-1.9
Body weight0.52.03.41.2-1.10.5-1.81.6-1.6-1.5-1.9-1.0
Weight adjusted by age0.30.41.60.3-0.21.10.5-0.10.1-0.20.3-1.3
Bone surface1.93.36.02.4-2.41.9-2.01.6-1.6-1.6-1.4-0.9
Bone volume2.33.95.62.4-2.31.7-2.31.9-1.9-1.9-1.8-1.2
Breakpoint value in progressive ratio session0.80.81.5-0.70.6-1.20.5-0.90.91.00.81.2
Number of licking bursts1.82.13.8-1.11.1-0.41.6-1.91.91.71.60.9
Context. condit. distance diff. score0.81.01.61.2-1.31.1-1.00.9-0.9-0.9-0.8-0.6
Locomotion velocity, session 12.62.84.9-1.51.4-0.71.6-2.22.21.81.71.4
Locomotion distance, session 10.81.01.9-1.11.0-0.60.8-1.41.41.00.80.7
Locomotion velocity, session 21.11.34.20.8-1.10.50.6-1.11.11.20.92.1
Locomotion distance, session 20.40.51.90.0-0.2-0.20.3-0.90.90.60.71.4
Locomotion velocity, session 30.20.20.40.6-0.60.1-0.60.4-0.4-0.6-0.30.1
Locomotion distance, session 30.91.01.70.4-0.4-0.2-1.31.3-1.3-1.3-1.1-0.6
Stereotopy head waving bouts, day 30.10.10.50.3-0.30.70.1-0.20.2-0.10.1-0.7
Stereotopy head waving duration, day 30.20.31.20.4-0.41.10.2-0.40.4-0.00.4-0.8
Locomotion velocity, session 73.23.45.11.8-1.81.3-2.31.8-1.8-2.2-2.0-1.6
Locomotion distance, session 72.12.74.01.6-1.60.9-1.91.8-1.8-2.0-1.6-1.2
Stereotopy head waving bouts, day 70.70.81.6-0.30.20.51.0-1.21.11.31.10.5
Stereotopy head waving duration, day 70.10.10.4-0.10.10.60.4-0.40.30.50.3-0.3
Locomotion velocity, session 80.10.20.50.6-0.70.6-0.1-0.0-0.0-0.2-0.10.0
Locomotion distance, session 80.40.51.61.1-1.21.1-0.1-0.20.2-0.00.30.7
Degree of sensitization distance0.20.20.30.5-0.60.50.1-0.40.40.30.40.4
Degree of sensitization stereotypy1.11.22.5-0.70.6-0.01.2-1.21.21.61.41.2
Conditioned locomotion1.11.32.30.4-0.20.2-1.21.4-1.3-1.4-1.5-1.5
Cocaine response after cond. corrected0.20.20.4-0.30.2-0.10.4-0.70.70.30.20.6
Cocaine response after cond. not corrected0.30.41.0-0.20.1-0.30.5-0.80.70.60.51.0
Cocaine response before conditioning0.30.40.8-0.10.0-0.50.6-0.60.60.70.90.9
Saline control response3.34.36.0-2.02.0-1.92.1-1.91.92.42.32.1
Bone: connectivity density3.25.09.73.1-3.13.0-2.01.8-1.8-1.5-1.5-1.3
Bone: cortical apparent density1.31.73.2-1.11.10.21.8-1.51.51.51.70.4
Bone: cortical area1.11.73.50.7-0.6-0.7-1.91.7-1.7-1.6-1.4-0.6
Bone: cortical porosity0.50.52.00.9-1.01.4-0.0-0.60.60.10.20.3
Bone: cortical porosity0.50.61.81.2-1.31.3-0.5-0.10.1-0.3-0.10.3
Bone: cortical thickness1.01.65.1-1.71.7-2.30.6-0.70.70.70.70.8
Bone: cortical thickness2.22.63.2-1.81.7-1.51.5-1.81.81.61.51.1
Bone: cortical tissue density1.31.73.2-1.01.00.41.8-1.51.51.51.70.4
Condit. Reinf. active minus inactive responses0.10.10.4-0.30.2-0.6-0.1-0.20.20.1-0.20.6
Condit. Reinf. active-inactive response ratio0.00.00.1-0.30.2-0.3-0.1-0.00.00.1-0.30.2
Condit. Reinf. active responses0.10.10.4-0.30.3-0.7-0.40.0-0.0-0.3-0.30.5
Condit. Reinf. inactive responses0.10.10.1-0.30.3-0.30.0-0.30.3-0.10.20.3
Incentive salience index mean0.60.71.9-0.90.8-1.40.4-0.60.60.50.41.2
Condit. Reinf. lever presses1.41.83.5-1.71.7-1.91.1-1.11.10.91.11.3
Condit. Reinf. active minus inactive responses2.73.43.81.9-1.81.7-1.91.9-1.8-1.9-2.0-1.8
Condit. Reinf. active-inactive response ratio1.81.93.81.4-1.32.0-1.11.1-1.1-1.1-1.4-1.6
Condit. Reinf. active responses1.21.72.60.7-0.50.2-1.51.6-1.6-1.6-1.5-1.4
Condit. Reinf. inactive responses0.70.84.4-1.21.3-2.1-0.00.3-0.2-0.20.00.2
Condit. Reinf. lever presses0.20.30.5-0.70.7-0.60.6-0.50.50.60.60.6
Condit. Reinf. lever reinforcers received0.60.81.30.4-0.3-0.0-1.01.1-1.1-1.1-1.1-1.0
Conditioned reinforcement - actives0.60.62.50.7-0.90.40.0-0.30.30.60.61.6
Conditioned reinforcement - inactives1.01.13.61.6-1.91.5-0.4-0.10.10.10.41.0
Conditioned locomotion0.10.10.2-0.20.2-0.20.1-0.20.20.30.40.5
Patch foraging indifference point 0 sec0.50.82.9-1.11.2-1.70.5-0.40.40.50.60.8
Patch foraging indifference point AUC5.56.47.8-2.52.4-2.42.4-2.62.62.82.52.6
Delay disc. indifference point, 0s delay0.80.82.11.4-1.41.4-0.60.4-0.4-0.0-0.9-0.3
Delay disc. indifference point, 16s delay1.61.63.5-0.70.6-0.71.3-1.41.41.41.91.4
Delay disc. indifference point, 2s delay0.20.20.50.1-0.10.70.3-0.40.40.30.3-0.6
Delay disc. indifference point, 24s delay2.22.12.7-1.31.2-1.31.4-1.61.61.31.61.6
Delay disc. indifference point, 4s delay1.21.32.6-0.40.4-0.11.2-1.51.51.61.31.2
Delay disc. indifference point, 8s delay2.12.23.4-1.61.6-1.01.5-1.81.81.41.40.5
Indifference point function ln k5.37.48.62.8-2.72.3-2.82.8-2.8-2.9-2.8-2.4
Indifference point function log k5.37.48.62.8-2.72.3-2.82.8-2.8-2.9-2.8-2.4
Patch foraging total patch changes 0 sec0.40.72.7-1.11.1-1.70.4-0.20.20.40.40.6
Patch foraging total patch changes 12 sec4.25.47.0-2.62.6-2.02.5-2.32.32.42.21.8
Patch foraging total patch changes 18 sec1.31.62.9-1.21.2-0.81.3-1.31.31.71.31.1
Patch foraging total patch changes 24 sec0.70.93.6-1.11.0-1.90.3-0.40.40.60.41.1
Patch foraging total patch changes 6 sec4.16.07.9-2.82.7-2.82.2-2.32.22.52.12.5
Patch foraging time to switch 0 sec0.81.32.3-0.90.9-0.01.5-1.51.51.11.20.4
Patch foraging water rate 0 sec1.11.82.81.3-1.40.6-1.71.6-1.6-1.3-1.4-0.5
Patch foraging water rate 12 sec0.60.92.00.8-0.8-0.3-1.41.3-1.3-0.9-0.9-0.2
Patch foraging water rate 18 sec1.11.52.91.4-1.50.3-1.71.3-1.4-1.3-1.0-0.2
Patch foraging water rate 24 sec0.81.11.71.1-1.10.2-1.31.1-1.1-1.1-1.2-0.5
Patch foraging water rate 6 sec0.10.20.20.4-0.40.2-0.50.4-0.4-0.5-0.4-0.5
Seeking ratio, delayed vs. immediate footshock0.20.20.4-0.50.6-0.70.20.1-0.10.40.50.4
Distance traveled before self-admin0.50.51.41.1-1.20.6-0.80.3-0.40.2-0.70.8
Distance traveled after self-admin1.51.74.92.0-2.12.2-0.70.6-0.6-0.3-0.2-0.3
Extensor digitorum longus weight0.20.91.90.8-0.70.2-1.41.1-1.1-1.0-1.3-0.5
Bone: elastic displacement0.50.62.70.3-0.21.4-0.10.1-0.1-0.4-0.7-1.6
Bone: elastic work0.70.92.91.0-1.01.7-0.50.3-0.3-0.6-0.7-1.3
Bone: endosteal estimation4.08.813.03.5-3.52.0-3.63.0-3.0-3.0-2.9-1.4
Bone: endosteal perimeter3.67.411.63.4-3.42.0-3.12.8-2.8-2.6-2.5-1.3
Epididymis fat weight1.84.28.11.2-1.01.0-2.12.2-2.1-2.5-2.5-2.8
Delta time in closed arm before/after self-admin0.50.52.0-0.90.9-1.4-0.40.3-0.3-0.6-0.1-0.4
Delta time in open arm before/after self-admin1.00.92.61.5-1.61.40.3-0.10.10.60.21.0
Diff in mean of infusions in LGA sessions1.51.72.61.5-1.60.9-1.61.2-1.2-1.2-1.4-0.5
Delay discount exponential model param1.01.11.80.7-0.70.4-1.11.4-1.3-1.2-1.3-0.8
Extinction: sum of active levers before priming0.20.20.8-0.00.0-0.9-0.60.4-0.3-0.2-0.30.4
Active lever presses in extinction session 61.41.34.32.0-2.11.8-0.70.1-0.1-0.3-0.4-0.1
Bone: final force0.10.20.80.1-0.1-0.9-0.70.1-0.1-0.3-0.10.8
Bone: final moment0.20.30.80.1-0.1-0.9-0.90.3-0.3-0.7-0.50.4
Food consumed during 24 hour testing period0.10.10.6-0.50.5-0.80.1-0.20.2-0.20.10.2
Glucose0.20.30.60.2-0.2-0.1-0.70.6-0.6-0.7-0.7-0.1
Heart weight0.50.72.5-1.11.2-1.6-0.30.4-0.4-0.4-0.7-0.2
Delay discount hyperbolic model param0.70.81.40.6-0.50.2-0.91.2-1.2-1.1-1.1-0.6
Intermittent access intake day 1-15 change2.12.14.82.1-2.21.3-1.51.3-1.3-0.8-1.20.3
Intermittent access intake escalation2.02.04.32.0-2.11.1-1.41.4-1.4-0.8-1.30.2
Intermittent access intake escalation 22.82.76.82.5-2.61.8-1.51.4-1.4-0.7-1.30.3
Intermitt. access day 1 inactive lever presses0.30.30.60.6-0.60.6-0.80.3-0.3-0.5-0.5-0.4
Intermitt. access day 15 inactive lever presses0.20.30.60.5-0.40.8-0.70.4-0.4-0.4-0.5-0.4
Intermitt. access escalation Index2.42.13.51.2-1.21.3-1.21.6-1.6-1.4-1.9-1.5
Intermittent access day 1 total infusions0.30.40.70.7-0.70.6-0.50.5-0.6-0.8-0.4-0.5
Intermittent access day 15 total infusions2.12.43.61.8-1.91.1-1.51.8-1.8-1.5-1.4-0.4
Intermittent access terminal intake (last 3 days)1.51.63.41.8-1.91.4-1.01.3-1.3-1.0-0.9-0.2
Intermittent access total infusions1.11.21.81.3-1.31.2-0.91.2-1.2-1.2-0.9-0.7
Intermittent access day 1 locomotion0.20.20.80.2-0.2-0.0-0.30.5-0.5-0.9-0.1-0.6
Intermittent access day 15 total locomotion0.60.71.3-0.60.5-0.70.8-0.80.80.81.01.1
Intermittent access total locomotion0.30.41.0-0.30.2-0.20.7-0.70.70.41.00.6
Intermittent access standard deviation2.42.64.52.0-2.11.3-1.91.6-1.6-1.2-1.50.1
Left kidney weight0.20.62.5-0.90.9-1.6-0.40.5-0.5-0.5-0.70.1
Right kidney weight0.72.07.8-2.22.2-2.80.4-0.20.20.20.10.8
Cocaine induced anxiety0.30.31.10.8-0.81.0-0.00.3-0.3-0.3-0.2-0.4
Post-drug Anxiety0.30.40.8-0.70.8-0.10.9-0.60.60.40.4-0.5
Baseline Anxiety0.60.61.7-1.21.3-1.20.3-0.60.60.30.3-0.1
Tail length0.51.42.80.1-0.1-1.4-1.71.6-1.6-1.2-1.1-0.3
Length with tail0.20.94.7-0.70.7-2.2-0.70.5-0.50.1-0.21.1
Length without tail0.51.03.3-0.80.7-1.60.3-0.50.61.00.61.8
Times rat made contact with spout0.20.20.50.7-0.70.7-0.1-0.10.1-0.1-0.1-0.3
Lifetime Intake0.40.40.90.8-0.80.9-0.50.6-0.6-0.7-0.3-0.5
Liver weight, left0.61.02.00.2-0.2-1.2-1.41.0-1.0-1.3-1.30.1
Liver weight, right0.30.50.90.0-0.0-0.9-0.90.8-0.8-0.9-1.00.1
Locomotor activity0.10.10.20.5-0.50.4-0.40.3-0.3-0.2-0.2-0.3
Locomotor testing distance0.10.10.40.6-0.60.4-0.30.2-0.3-0.00.00.1
Locomotor testing rearing0.40.71.81.3-1.30.8-0.80.7-0.70.1-0.30.5
Locomotion in novel chamber1.92.45.82.2-2.22.4-1.21.1-1.0-1.0-0.7-1.0
Locomotion in novel chamber post-restriction1.01.23.9-0.30.2-0.40.8-1.01.11.31.42.0
Fecal boli incidents, locomotor time 10.40.41.50.9-0.91.20.00.1-0.1-0.20.3-0.6
Change in fecal boli incidents, locomotor task0.90.81.5-0.90.9-1.20.8-0.60.70.80.81.2
Time >=10cm from walls, locomotor time 10.70.73.50.0-0.2-1.5-0.40.4-0.40.1-0.21.9
Bouts of movement, locomotor time 10.20.20.4-0.30.3-0.20.6-0.70.60.50.50.0
Total resting periods, locomotor time 10.70.71.4-0.50.4-0.30.9-1.21.11.01.00.7
Rest time, locomotor task time 10.60.61.40.6-0.71.20.5-0.90.90.90.80.5
Distance moved, locomotor task time 10.60.72.6-0.70.7-1.6-0.60.8-0.7-0.6-0.70.3
Vertical activity count, locomotor time 10.40.41.9-0.60.6-1.4-0.00.5-0.5-0.4-0.30.3
Time >=10cm from walls, locomotor time 20.30.31.50.4-0.6-0.4-0.60.3-0.40.2-0.41.2
Bouts of movement, locomotor time 23.84.17.3-1.31.2-1.02.2-2.22.22.72.61.9
Total resting periods, locomotor time 24.24.58.1-1.31.1-1.12.2-2.32.32.92.72.2
Rest time, locomotor task time 21.72.03.1-0.70.6-0.51.4-1.71.71.71.81.7
Distance moved, locomotor task time 22.02.45.20.7-0.6-0.0-2.01.8-1.8-1.8-2.3-1.1
Vertical activity count, locomotor time 20.70.71.40.5-0.60.1-0.81.0-1.0-1.2-1.2-0.7
Light reinforcement 10.10.20.4-0.40.50.20.6-0.40.40.40.5-0.3
Light reinforcement 21.11.52.6-1.11.10.61.6-1.61.61.01.4-0.4
Bone: marrow area4.18.912.93.6-3.62.1-3.63.0-3.0-3.1-2.9-1.5
Bone: maximum diameter4.48.110.93.3-3.32.2-3.23.1-3.1-2.7-2.6-1.8
Bone: maximum force0.30.51.21.0-1.00.1-1.10.5-0.5-0.9-0.50.2
Bone: maximum moment0.50.81.90.9-1.00.1-1.40.8-0.8-1.3-1.0-0.4
Mean time between licks in bursts0.20.20.9-0.50.6-1.00.10.4-0.40.0-0.10.1
Mean num. licks in bursts2.63.14.11.8-1.81.0-1.92.0-2.0-2.0-1.8-1.3
Cd content in liver0.90.93.0-1.71.7-1.50.4-0.20.10.10.1-0.4
Co content in liver0.60.73.4-0.81.0-0.20.10.6-0.6-0.6-0.5-1.8
Cu content in liver5.87.010.8-2.52.4-1.42.9-3.33.32.82.52.3
Fe content in liver1.41.72.3-1.41.4-0.71.4-1.51.51.51.21.0
K content in liver0.80.82.3-0.0-0.10.00.8-1.11.11.01.01.5
Mg content in liver1.51.63.3-0.70.5-0.51.1-1.51.51.51.31.8
Mn content in liver4.65.39.3-1.61.4-0.42.6-3.13.02.52.72.0
Na content in liver2.52.64.2-1.11.0-0.21.9-2.02.11.82.01.5
Rb content in liver0.20.20.80.2-0.3-0.1-0.90.1-0.2-0.3-0.70.3
Se content in liver18.722.930.5-4.84.6-2.75.5-5.55.54.95.23.6
Sr content in liver0.00.00.1-0.10.0-0.30.2-0.0-0.00.00.20.1
Zn content in liver1.11.21.6-1.31.2-0.81.3-1.31.30.81.00.7
Bone: minimum diameter6.412.017.23.6-3.61.6-4.14.1-4.1-3.7-3.4-2.0
Time in familiar zone, hab. session 10.60.52.30.5-0.41.0-0.40.2-0.2-0.7-0.6-1.5
Time in novel zone, hab. session 10.70.72.0-0.50.4-0.70.7-0.60.60.81.11.4
Total zone transitions, hab. session 10.20.20.70.0-0.10.10.2-0.60.60.50.70.8
Total locomotion distance, hab. session 11.01.52.7-1.21.1-0.71.0-1.61.61.11.21.1
Locomotion velocity, hab. session 11.82.64.0-1.71.7-1.21.4-2.02.01.41.51.3
Time in familiar zone, hab. session 20.50.52.3-0.50.6-0.2-0.20.7-0.7-0.6-0.5-1.5
Time in novel zone, hab. session 20.30.31.1-0.0-0.1-0.00.3-0.60.60.50.41.0
Total zone transitions, hab. session 20.71.01.2-1.11.1-1.00.9-0.90.90.91.01.0
Total locomotion distance, hab. session 20.70.92.0-1.41.4-1.20.7-0.90.90.40.60.2
Locomotion velocity, hab. session 20.91.22.0-1.41.4-1.11.0-1.21.20.81.00.6
Novel to familiar place preference ratio1.71.85.52.2-2.42.2-0.3-0.20.20.20.10.7
Novelty place preference1.81.95.92.2-2.42.3-0.3-0.20.20.20.10.7
Time in novel zone, NPP test1.81.95.92.3-2.42.3-0.4-0.10.10.1-0.00.6
Total zone transitions, NPP test0.71.02.3-1.31.2-1.50.5-0.80.80.60.61.0
Total locomotion distance, NPP test1.82.53.5-1.91.8-1.61.3-1.81.81.31.21.3
Locomotion velocity, NPP test1.82.53.3-1.81.8-1.71.2-1.71.71.31.31.5
Intraocular pressure0.20.30.5-0.70.7-0.10.6-0.60.60.40.3-0.4
Delta distance traveled before/after self-admin1.21.33.31.5-1.41.8-0.70.9-0.8-1.0-0.4-1.3
Delta ambulatory time before/after self-admin2.12.34.11.9-1.82.0-1.11.3-1.3-1.4-0.8-1.4
Parametrial fat weight0.40.71.3-0.80.8-1.1-0.70.9-0.9-0.8-0.9-0.7
Pavlov. Cond. lever latency0.10.20.9-0.20.30.20.20.3-0.3-0.1-0.1-0.9
Pavlov. Cond. magazine entry latency0.60.72.5-1.00.9-1.60.4-0.50.50.20.61.1
Pavlov. Cond. change in total contacts0.10.10.4-0.10.0-0.5-0.50.2-0.2-0.6-0.40.2
Pavlov. Cond. index score0.50.61.7-0.60.5-1.20.4-0.70.70.40.71.3
Pavlov. Cond. latency score0.40.51.8-0.50.4-1.20.2-0.60.50.40.61.3
Pavlov. Cond. lever contacts0.60.71.7-0.70.6-1.20.3-0.70.70.50.71.3
Pavlov. Cond. magazine entry number0.20.20.60.3-0.20.80.4-0.30.30.70.40.1
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.2-0.3-0.2-0.10.1-0.2-0.2-0.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.60.5-1.10.3-0.60.60.30.71.1
Pavlov. Cond. response bias0.20.31.3-0.50.4-1.1-0.1-0.20.2-0.20.10.8
Pavlov. Cond. lever latency1.11.52.91.6-1.61.7-0.91.1-1.1-0.9-0.9-1.0
Pavlov. Cond. magazine entry latency0.20.20.6-0.20.1-0.8-0.60.1-0.2-0.6-0.70.1
Pavlov. Cond. change in total contacts0.30.41.4-0.90.9-1.20.3-0.40.40.20.20.6
Pavlov. Cond. index score0.50.72.2-1.11.0-1.50.4-0.70.70.40.40.9
Pavlov. Cond. latency score0.40.51.8-0.90.8-1.30.2-0.60.60.30.30.8
Pavlov. Cond. lever contacts1.01.43.2-1.51.5-1.80.8-0.90.90.90.81.0
Pavlov. Cond. magazine entry number1.11.44.41.6-1.52.1-0.40.9-0.9-0.5-0.3-1.0
Pavlov. Cond. intertrial magazine entries0.81.01.71.3-1.21.3-0.70.9-0.9-0.7-0.6-1.1
Pavlov. Cond. lever-magazine prob. diff.0.50.62.0-0.90.8-1.40.3-0.70.70.40.41.0
Pavlov. Cond. response bias1.01.33.7-1.51.4-1.90.6-0.90.80.70.61.1
Time in closed arm before self-admin0.80.92.91.4-1.41.7-0.60.4-0.4-0.3-0.5-0.6
Time in closed arm after self-admin0.10.10.6-0.40.5-0.8-0.2-0.10.10.20.1-0.0
Time in open arm before self-admin0.30.31.2-0.30.5-0.2-0.30.3-0.3-0.7-0.5-1.1
Time in open arm after self-admin0.30.30.80.7-0.70.60.5-0.30.30.60.40.9
Bone: periosteal estimation2.55.29.02.5-2.51.0-3.02.4-2.4-2.5-2.3-1.0
Bone: periosteal perimeter2.94.97.12.5-2.41.2-2.72.4-2.4-2.3-2.1-1.3
Bone: post-yield work0.60.81.11.0-1.10.1-1.10.9-0.9-1.0-0.8-0.2
Progressive ratio test 1 active lever presses0.40.41.00.8-0.81.0-0.40.3-0.3-0.5-0.2-0.5
Progressive ratio test 1 breakpoint0.40.41.10.9-0.91.0-0.40.3-0.3-0.5-0.2-0.5
Progressive ratio test 1 inactive lever presses2.32.53.61.9-1.91.7-1.81.3-1.3-1.5-1.2-1.2
Progressive ratio test 2 active lever presses0.80.92.51.5-1.61.2-0.70.6-0.7-0.7-0.4-0.2
Progressive ratio test 2 breakpoint1.01.13.11.7-1.81.3-0.80.7-0.8-0.8-0.5-0.3
Progressive ratio test 2 inactive lever presses0.80.93.01.5-1.61.7-0.50.2-0.3-0.3-0.2-0.2
Incentive Sensitization - Responses1.81.84.52.0-2.11.5-1.01.1-1.1-1.0-0.8-0.4
Incentive Sensitization - Breakpoint1.51.53.81.8-1.91.3-0.91.0-1.1-1.0-0.8-0.4
Sum of active levers in priming session hrs 5-60.20.10.60.1-0.10.3-0.20.1-0.1-0.4-0.6-0.8
Progressive ratio0.91.12.4-0.30.5-0.6-1.11.0-1.0-1.3-1.2-1.5
Food seeking constrained by brief footshock0.60.72.9-0.30.1-1.6-0.50.0-0.10.40.21.7
Seeking ratio, punishment vs. effort1.11.46.3-0.1-0.1-0.90.6-0.90.91.41.22.5
Retroperitoneal fat weight0.61.84.0-0.00.2-0.5-1.41.3-1.3-1.9-1.8-2.0
Reaction time number correct1.82.64.62.1-2.11.9-1.31.4-1.4-1.4-1.2-1.2
Reaction time mean minus median0.91.22.50.3-0.2-0.2-1.11.4-1.5-1.6-1.4-1.0
Reaction time mean minus median AUC0.91.22.40.2-0.1-0.1-1.01.3-1.3-1.6-1.4-1.4
Reaction time num false alarms0.20.31.9-0.50.5-1.40.00.3-0.20.20.30.6
Reaction time num false alarms AUC0.30.42.4-0.50.5-1.6-0.20.4-0.40.00.10.6
Reaction time trials correct on left1.82.64.62.1-2.11.9-1.31.4-1.4-1.4-1.2-1.2
Reaction time trials on left1.82.64.42.1-2.11.8-1.41.5-1.5-1.5-1.2-1.2
Reaction time mean0.50.62.5-1.21.2-1.60.00.2-0.2-0.3-0.1-0.1
Reaction time mean AUC0.60.82.8-1.41.4-1.70.4-0.20.1-0.10.20.2
Median of all reaction times0.50.72.4-1.31.4-1.50.3-0.20.10.00.10.0
Reaction time omissions2.93.97.50.7-0.60.1-2.22.4-2.5-2.7-2.3-2.2
Reaction time false alarm rate0.91.34.9-1.51.5-2.20.5-0.40.40.70.71.0
Reaction time premature initiation rate0.40.52.3-1.00.9-1.5-0.0-0.00.00.1-0.10.7
Reaction time premature initiations0.30.40.80.2-0.2-0.5-0.80.9-0.9-0.8-0.9-0.1
Std. dev. reaction times1.01.42.7-0.50.5-1.2-1.01.4-1.4-1.6-1.3-1.1
Reaction time trials completed1.82.64.42.1-2.11.8-1.41.5-1.5-1.5-1.2-1.2
Reaction time trials AUC1.62.34.02.0-2.01.8-1.31.4-1.4-1.4-1.1-1.2
Run reversals in cocaine runway, females0.20.20.6-0.20.2-0.10.5-0.80.80.60.4-0.1
Run reversals in cocaine runway, males3.43.33.9-2.01.9-1.91.7-1.81.82.01.41.9
Latency to leave start box in cocaine runway4.14.45.51.7-1.51.6-2.32.3-2.3-2.3-2.3-2.4
Latency to leave start box in cocaine runway, F4.34.65.52.2-2.02.0-2.32.3-2.3-2.1-2.2-1.9
Latency to leave start box in cocaine runway, M1.21.12.40.2-0.10.1-1.21.2-1.2-1.4-1.2-1.5
Std. dev. time between licks in bursts1.01.23.5-1.81.9-1.30.9-0.80.80.50.4-0.3
Total sessions with >9 infusions0.40.41.1-0.40.4-0.10.6-0.80.80.71.00.7
Short access day 1 total inactive lever presses2.32.69.41.8-1.73.1-0.60.8-0.8-1.1-1.0-2.1
Short access day 10 total inactive lever presses0.10.10.60.1-0.10.4-0.30.2-0.2-0.2-0.5-0.8
Short access day 1 total infusions0.50.51.0-0.70.70.20.8-0.80.80.51.0-0.2
Short access day 10 total infusions0.20.20.6-0.70.8-0.5-0.10.2-0.2-0.40.0-0.5
Short access total infusions0.10.10.2-0.10.10.40.2-0.20.20.10.5-0.1
Short access day 1 locomotion0.10.20.40.2-0.20.50.3-0.50.50.30.60.0
Short access day 10 total locomotion0.10.10.3-0.10.00.20.3-0.40.3-0.40.5-0.6
Short access total locomotion0.30.30.8-0.40.40.20.6-0.70.70.60.90.2
One hour access (0.3 mA shock)2.73.17.72.6-2.82.0-1.61.4-1.5-1.4-0.8-0.2
Compulsive drug intake3.73.76.11.7-1.71.4-2.52.2-2.3-1.8-2.1-1.2
One hour access (shock baseline)0.30.31.21.0-1.10.5-0.10.4-0.3-0.50.10.1
Social response proportion2.22.47.52.0-2.02.7-1.00.9-0.9-1.0-0.7-1.3
Social responses0.40.51.31.0-0.91.2-0.40.5-0.5-0.3-0.1-0.5
Social time0.70.91.7-0.60.6-0.81.0-0.80.91.01.21.3
Soleus weight1.13.24.11.9-1.81.2-1.91.8-1.8-2.0-2.0-1.6
Bone: stiffness0.40.71.41.0-1.1-0.1-1.20.9-0.9-0.9-0.60.3
Tibialis anterior weight0.41.32.31.5-1.50.9-1.51.1-1.1-0.8-1.3-0.1
Time to tail flick, vehicle, before self-admin0.80.81.8-0.40.50.81.3-1.21.21.00.9-0.3
Time to tail flick, vehicle, after self-admin0.40.41.20.8-0.8-0.4-1.10.5-0.5-0.5-0.50.4
Time to tail flick, test, before self-admin1.21.23.41.7-1.81.4-1.00.6-0.6-0.6-0.40.2
Time to tail flick, test, after self-admin1.11.12.21.4-1.31.5-0.90.8-0.8-0.6-1.1-0.9
Delta time to tail flick, vehicle, before/after SA1.41.43.71.3-1.4-0.4-1.91.2-1.2-1.1-1.10.3
Delta time to tail flick, test, before/after SA0.10.10.40.1-0.00.2-0.20.3-0.3-0.1-0.6-0.6
Tibia length0.10.31.3-0.60.7-1.1-0.20.2-0.20.1-0.00.5
Ambulatory time before self-admin0.30.30.80.8-0.90.6-0.50.2-0.20.3-0.60.6
Ambulatory time after self-admin2.93.19.62.8-2.83.1-1.10.7-0.8-0.6-0.5-0.4
Bone: tissue strength0.30.20.70.2-0.2-0.1-0.60.4-0.4-0.8-0.7-0.5
Total heroin consumption0.30.31.1-0.60.5-1.00.3-0.60.60.40.30.5
Bone: trabecular number1.92.95.42.3-2.32.2-1.81.4-1.4-1.2-1.3-0.9
Bone: trabecular spacing0.91.13.4-1.71.7-1.80.6-0.30.20.40.20.2
Bone: trabecular thickness2.12.53.31.8-1.81.3-1.81.6-1.6-1.6-1.5-1.1
Bone: trabecular tissue density0.30.50.80.9-0.90.8-0.60.8-0.8-0.4-0.4-0.4
Water consumed over 24 hours0.40.41.21.1-1.10.9-0.60.1-0.2-0.4-0.4-0.3
Number of responses in last shaping day0.60.61.90.4-0.31.3-0.30.5-0.5-0.7-0.6-1.4