Plcb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC mRNA stability Plcb1 0.1 0.09 1.1e-03 0.05 0.04 0.04 0.04 2.7e-03 6.7e-03 1.1e-02 8.6e-03
2 Adipose mRNA stability Plcb1 0.08 0.05 6.0e-09 0.07 0 0.06 0 2.9e-08 1.6e-01 1.8e-07 3.4e-01
3 Adipose gene expression Plcb1 0.1 0.06 3.0e-07 0.05 0.01 0.03 0.01 4.4e-06 2.8e-02 1.1e-04 1.8e-02
4 OFC gene expression Plcb1 0.33 0.16 2.2e-08 0.37 0.35 0.36 0.37 9.0e-10 3.0e-09 1.5e-09 9.2e-10
5 Liver isoform ratio NM_001077641.2 0.01 0.01 7.4e-03 0.01 -0 0 0 4.7e-02 5.6e-01 3.0e-01 2.2e-01
6 Liver mRNA stability Plcb1 0.08 0.06 6.1e-04 0.02 -0 0.03 0.02 5.7e-03 4.8e-01 6.4e-04 2.4e-03
7 PL mRNA stability Plcb1 0.08 0.07 1.7e-06 0.06 0.05 0.06 0.06 6.4e-07 1.5e-06 9.0e-07 5.5e-07
8 Brain gene expression Plcb1 0.6 0.11 0.0e+00 0.58 0.57 0.58 0.58 1.8e-66 3.7e-64 2.7e-65 2.5e-65
9 Liver gene expression Plcb1 0.05 0.03 3.0e-07 0.04 0.02 0.04 0.02 8.5e-05 1.6e-03 6.2e-05 9.2e-04
10 NAcc gene expression Plcb1 0.04 0.03 4.2e-06 0.03 0.03 0.03 0.03 6.3e-05 7.6e-06 1.5e-05 2.2e-05
11 PL gene expression Plcb1 0.27 0.17 0.0e+00 0.24 0.24 0.24 0.24 1.5e-25 5.4e-26 3.8e-26 1.7e-26
12 IC gene expression Plcb1 0.66 0 0.0e+00 0.45 0.48 0.47 0.47 7.4e-21 1.1e-22 3.4e-22 4.4e-22
13 OFC mRNA stability Plcb1 0.29 0.17 1.2e-05 0.23 0.22 0.21 0.22 4.4e-06 4.7e-06 1.0e-05 5.2e-06
14 PL isoform ratio XM_017591467.3 0.02 0.02 7.8e-03 0.01 0 0 0.01 3.8e-02 7.4e-02 3.0e-01 4.4e-02
15 pVTA mRNA stability Plcb1 0.17 0.07 0.0e+00 0.24 0.26 0.24 0.25 1.3e-19 1.3e-20 1.1e-19 9.4e-20
16 Brain mRNA stability Plcb1 0.18 0.09 1.8e-12 0.11 0.13 0.12 0.12 3.1e-10 4.5e-12 7.0e-11 7.8e-11
17 IL gene expression Plcb1 0.22 0.14 1.7e-04 0.11 0.11 0.07 0.11 1.5e-03 1.3e-03 9.2e-03 1.4e-03
18 BLA mRNA stability Plcb1 0.07 0.08 5.8e-03 0.03 0.02 0.01 0.02 6.7e-03 2.6e-02 1.2e-01 2.2e-02
19 BLA gene expression Plcb1 0.28 0.12 1.2e-13 0.24 0.23 0.2 0.23 4.8e-13 2.2e-12 5.2e-11 1.7e-12
20 Brain intron excision ratio chr3_143138850_143150657 0.03 0.02 1.2e-03 0.02 0.03 0.02 0.02 6.4e-03 1.3e-03 8.5e-03 4.7e-03
21 PL intron excision ratio chr3_143138850_143150657 0.02 0.01 3.8e-03 0.01 0.01 0 0.01 3.9e-02 9.9e-03 1.9e-01 3.0e-02
22 NAcc mRNA stability Plcb1 0.06 0.07 9.3e-06 0.03 0.02 0.02 0.02 6.7e-05 1.2e-04 8.9e-04 2.7e-04
23 RMTg alternative TSS NM_001077641.2 0.14 0.11 4.2e-03 0.06 0.04 0.02 0.06 1.3e-02 3.8e-02 9.8e-02 9.9e-03
24 RMTg alternative TSS XM_017591467.3 0.13 0.11 3.9e-03 0.06 0.04 0.02 0.06 1.1e-02 3.4e-02 8.3e-02 8.4e-03
25 Brain intron excision ratio chr3_143138850_143222448 0.02 0.02 5.4e-03 0 0.01 0 0 2.7e-01 2.3e-02 1.4e-01 3.4e-01
26 IL mRNA stability Plcb1 0.19 0.16 5.3e-03 0.05 0.04 0.03 0.03 2.5e-02 4.0e-02 6.3e-02 7.3e-02
27 NAcc intron excision ratio chr3_143138850_143222448 0.04 0.03 1.8e-05 0.03 0.02 0.02 0.03 6.2e-05 1.1e-04 2.0e-04 1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density2.54.35.62.12.22.12.2-2.12.42.12.2-2.12.12.12.12.22.12.12.22.02.12.02.02.02.1-2.12.1-1.92.2-0.7
Area under the delay curve0.10.10.40.50.40.50.4-0.10.30.6-0.0-0.50.10.30.2-0.0-0.00.10.10.20.4-0.10.20.20.3-0.40.4-0.20.5-0.4
BMI with tail1.65.57.4-2.5-2.3-2.4-2.32.2-1.7-2.4-2.32.3-2.5-2.3-2.4-2.2-2.3-2.3-2.3-2.4-2.5-2.3-2.3-2.3-2.72.4-2.42.3-2.52.1
BMI without tail0.41.22.51.11.01.01.0-1.00.31.11.2-1.21.01.11.11.21.01.10.81.21.01.01.21.20.8-1.11.1-1.30.9-1.6
Body weight0.52.05.31.41.41.41.4-1.30.41.41.3-1.61.11.41.41.41.31.40.71.61.31.31.71.71.2-1.41.4-1.81.2-2.3
Weight adjusted by age0.10.20.80.50.80.60.8-0.10.90.60.3-0.50.20.30.30.30.30.10.20.3-0.10.30.30.3-0.0-0.20.2-0.3-0.0-0.1
Bone surface0.91.62.81.31.21.31.2-1.31.71.31.3-1.31.31.31.21.31.21.21.51.11.31.31.21.11.3-1.41.4-1.01.30.1
Bone volume1.83.24.31.91.81.91.8-1.82.11.91.8-1.91.81.81.81.91.81.81.91.71.81.81.71.71.8-1.91.9-1.61.9-0.4
Breakpoint value in progressive ratio session0.10.20.60.1-0.00.2-0.00.8-0.40.2-0.5-0.3-0.7-0.3-0.4-0.4-0.6-0.4-0.8-0.2-0.6-0.6-0.1-0.1-0.30.2-0.20.00.0-0.3
Number of licking bursts1.93.14.81.71.61.71.6-1.91.11.72.2-1.61.91.71.92.11.81.91.81.81.81.81.81.81.8-1.81.8-1.81.6-1.7
Context. condit. distance diff. score0.00.00.2-0.0-0.1-0.0-0.1-0.2-0.4-0.10.30.10.20.00.20.40.10.20.10.20.20.00.10.10.2-0.10.1-0.20.1-0.4
Locomotion velocity, session 13.94.26.02.11.92.01.9-2.32.32.12.1-1.92.32.12.12.02.22.12.51.92.32.31.81.82.2-2.22.2-1.72.0-0.3
Locomotion distance, session 16.07.613.32.92.82.92.8-2.93.62.92.6-2.73.02.92.72.52.92.73.32.52.82.92.52.42.8-2.82.8-2.22.8-0.3
Locomotion velocity, session 20.70.80.9-0.9-1.0-0.9-1.00.9-0.8-1.0-0.80.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.8-0.8-0.8-0.80.9-0.90.8-0.90.7
Locomotion distance, session 23.65.110.82.32.42.32.4-2.33.32.42.2-2.12.52.32.22.12.42.12.82.02.22.31.91.82.3-2.32.3-1.72.40.2
Locomotion velocity, session 31.61.97.01.31.31.31.3-1.32.61.31.3-1.01.61.31.21.41.31.22.00.91.31.30.90.81.4-1.41.4-0.61.31.4
Locomotion distance, session 33.43.75.62.02.02.02.0-1.82.42.02.1-2.02.01.91.92.12.01.92.11.81.91.91.91.82.0-2.12.1-1.71.9-0.3
Stereotopy head waving bouts, day 30.60.72.3-0.7-0.6-0.7-0.60.80.1-0.6-1.10.8-0.7-0.7-0.9-1.0-0.8-0.9-0.4-1.0-0.7-0.8-1.0-1.0-0.60.6-0.61.1-0.51.5
Stereotopy head waving duration, day 31.82.23.2-1.4-1.3-1.4-1.31.5-0.6-1.4-1.81.6-1.3-1.4-1.6-1.6-1.6-1.6-1.1-1.6-1.4-1.5-1.7-1.7-1.41.4-1.41.7-1.31.7
Locomotion velocity, session 72.83.13.91.71.71.71.7-1.91.31.62.0-1.51.91.81.91.91.81.91.81.81.91.81.71.81.9-1.71.7-1.71.7-1.5
Locomotion distance, session 73.74.75.82.12.12.12.1-2.41.72.02.4-2.02.32.22.32.42.22.32.22.22.32.32.22.22.3-2.12.1-2.22.1-1.8
Stereotopy head waving bouts, day 70.10.10.7-0.1-0.3-0.1-0.30.40.2-0.1-0.50.3-0.2-0.3-0.4-0.5-0.4-0.5-0.1-0.5-0.4-0.4-0.5-0.5-0.30.1-0.10.6-0.10.8
Stereotopy head waving duration, day 70.20.21.1-0.2-0.3-0.2-0.30.40.3-0.1-0.60.4-0.2-0.3-0.4-0.6-0.3-0.5-0.0-0.5-0.4-0.4-0.6-0.6-0.30.1-0.10.7-0.11.0
Locomotion velocity, session 80.80.94.1-0.8-0.8-0.8-0.80.90.4-0.8-0.81.1-0.5-0.8-0.9-0.7-1.0-1.0-0.1-1.1-0.9-0.9-1.3-1.3-0.80.7-0.71.4-0.72.0
Locomotion distance, session 81.82.54.21.51.51.51.5-1.82.01.51.7-1.31.91.61.61.71.71.62.01.41.71.61.41.31.8-1.61.6-1.21.7-0.1
Degree of sensitization distance0.50.52.50.60.70.60.7-0.9-0.10.50.6-0.60.70.70.70.60.60.70.40.80.70.70.80.80.7-0.50.5-0.90.7-1.6
Degree of sensitization stereotypy0.10.10.20.40.10.30.1-0.20.30.40.2-0.20.30.20.20.20.20.10.40.10.10.20.10.10.3-0.40.4-0.10.30.1
Conditioned locomotion0.10.10.30.30.30.30.3-0.20.20.40.3-0.50.20.30.30.50.30.40.10.40.20.20.50.50.3-0.40.4-0.50.4-0.2
Cocaine response after cond. corrected3.44.16.5-2.1-2.2-2.1-2.22.1-2.6-2.1-2.12.0-2.1-2.1-2.0-2.0-1.9-2.0-2.3-1.9-2.1-2.0-1.9-1.8-2.12.1-2.11.7-2.10.5
Cocaine response after cond. not corrected1.61.82.6-1.3-1.4-1.3-1.41.5-1.6-1.3-1.61.2-1.4-1.4-1.4-1.5-1.2-1.4-1.5-1.3-1.4-1.3-1.3-1.3-1.41.4-1.41.2-1.40.4
Cocaine response before conditioning2.02.44.21.71.61.71.6-1.52.01.71.3-1.61.61.61.51.31.51.41.81.41.61.51.31.31.5-1.71.7-1.21.6-0.2
Saline control response3.04.05.22.32.22.32.2-1.81.62.21.4-2.31.82.11.91.41.81.81.62.02.01.92.12.02.0-2.22.2-2.12.2-2.1
Bone: connectivity density1.01.52.51.31.31.31.3-1.21.61.31.3-1.31.21.31.21.31.21.21.31.11.21.21.21.11.2-1.31.3-1.11.3-0.0
Bone: cortical apparent density1.62.26.91.41.51.41.5-1.30.31.41.4-1.61.21.41.51.41.41.50.71.71.41.41.71.81.4-1.41.4-1.91.4-2.6
Bone: cortical area3.45.25.72.32.32.32.3-2.41.92.32.1-2.42.32.42.32.22.32.32.22.32.42.32.32.32.3-2.42.4-2.32.3-1.8
Bone: cortical porosity6.77.27.8-2.8-2.8-2.8-2.82.7-2.1-2.8-2.62.7-2.7-2.7-2.7-2.6-2.7-2.7-2.5-2.8-2.7-2.7-2.7-2.7-2.72.7-2.72.7-2.82.5
Bone: cortical porosity3.94.24.7-2.2-2.2-2.2-2.22.1-1.6-2.2-1.92.1-2.0-2.1-2.1-1.9-2.1-2.0-1.9-2.1-2.1-2.1-2.1-2.1-2.12.0-2.02.1-2.11.9
Bone: cortical thickness3.96.57.52.52.52.52.5-2.61.52.52.4-2.72.52.62.62.52.62.62.22.72.62.62.72.72.6-2.62.6-2.72.5-2.7
Bone: cortical thickness2.12.42.81.61.51.61.5-1.61.01.61.4-1.61.51.61.61.51.61.61.41.61.61.51.61.61.6-1.71.7-1.61.6-1.5
Bone: cortical tissue density1.62.17.11.41.41.41.4-1.30.21.41.4-1.51.11.41.41.41.31.50.71.61.41.31.71.71.4-1.31.3-1.91.3-2.7
Condit. Reinf. active minus inactive responses0.70.71.60.90.80.90.8-0.91.30.80.9-0.90.90.90.80.90.80.81.00.70.90.80.80.71.0-0.90.9-0.61.00.4
Condit. Reinf. active-inactive response ratio0.00.00.10.2-0.00.2-0.0-0.00.10.20.1-0.2-0.00.10.10.1-0.00.10.00.10.10.00.10.10.2-0.20.2-0.10.30.2
Condit. Reinf. active responses0.70.91.10.90.80.90.8-1.11.00.81.1-1.00.90.91.01.11.01.00.90.90.90.91.01.00.9-0.90.9-0.91.0-0.2
Condit. Reinf. inactive responses0.50.61.00.60.70.60.7-0.90.70.70.9-0.70.80.70.80.91.00.90.70.80.70.90.80.80.6-0.60.6-0.80.6-0.4
Incentive salience index mean1.11.43.11.21.11.21.1-1.31.81.11.2-1.11.31.21.11.21.21.11.51.01.21.21.00.91.2-1.21.2-0.81.30.6
Condit. Reinf. lever presses0.81.12.61.01.01.01.0-1.21.61.00.9-0.81.31.11.00.81.31.01.50.91.21.20.80.81.1-1.01.0-0.71.10.3
Condit. Reinf. active minus inactive responses1.82.36.01.71.71.61.7-1.52.51.61.4-1.41.71.61.41.41.41.42.01.31.51.51.21.11.5-1.61.6-1.01.60.3
Condit. Reinf. active-inactive response ratio5.36.18.82.72.62.72.6-2.43.02.62.4-2.52.62.62.52.32.42.42.72.42.52.52.32.22.5-2.62.6-2.22.6-0.8
Condit. Reinf. active responses1.82.55.91.71.71.71.7-1.62.41.71.4-1.41.81.71.51.51.51.42.11.31.61.51.21.21.6-1.61.6-1.11.70.1
Condit. Reinf. inactive responses0.00.00.20.10.10.10.1-0.10.40.10.00.10.20.10.00.10.00.00.3-0.00.1-0.0-0.1-0.10.1-0.00.00.10.10.3
Condit. Reinf. lever presses2.02.74.81.71.61.61.6-1.82.01.61.8-1.42.01.71.71.81.81.72.21.51.81.71.41.41.7-1.61.6-1.31.7-0.3
Condit. Reinf. lever reinforcers received2.13.06.21.91.91.91.9-1.72.51.81.6-1.52.01.81.71.71.71.62.21.51.71.71.41.31.7-1.81.8-1.21.8-0.1
Conditioned reinforcement - actives0.71.12.10.80.80.90.8-1.20.20.81.4-0.91.11.01.21.31.21.21.01.21.31.11.21.21.0-0.90.9-1.20.7-1.4
Conditioned reinforcement - inactives1.62.43.21.51.71.51.7-1.51.41.41.7-1.41.61.61.61.61.61.61.61.61.61.61.61.61.8-1.41.4-1.51.3-1.3
Conditioned locomotion3.64.66.32.01.92.01.9-2.31.62.02.5-1.92.42.22.32.32.52.42.32.22.32.32.22.22.3-2.12.1-2.11.9-1.6
Patch foraging indifference point 0 sec0.10.20.60.50.50.70.5-0.20.70.8-0.0-0.60.30.50.2-0.00.30.20.40.30.30.30.30.20.3-0.30.3-0.20.20.0
Patch foraging indifference point AUC1.62.35.91.82.11.92.1-1.32.41.91.2-1.71.41.61.41.21.31.21.61.31.21.11.31.21.3-1.51.5-1.21.4-0.5
Delay disc. indifference point, 0s delay0.10.10.5-0.2-0.4-0.2-0.4-0.2-0.1-0.1-0.00.30.1-0.2-0.1-0.10.1-0.10.2-0.20.00.0-0.3-0.3-0.1-0.10.10.30.10.7
Delay disc. indifference point, 16s delay0.40.41.0-0.4-0.3-0.4-0.30.6-0.4-0.3-1.00.3-0.8-0.5-0.8-1.0-0.8-0.8-0.8-0.6-0.8-0.9-0.6-0.6-0.60.6-0.60.6-0.50.1
Delay disc. indifference point, 2s delay1.71.92.91.31.11.31.1-1.71.41.51.5-1.31.51.31.41.51.51.51.61.31.71.41.31.31.5-1.31.3-1.11.4-0.1
Delay disc. indifference point, 24s delay0.30.31.0-0.2-0.2-0.2-0.20.7-0.8-0.1-1.00.2-0.6-0.4-0.6-1.0-0.9-0.8-0.8-0.5-0.4-0.9-0.5-0.5-0.20.3-0.30.3-0.1-1.0
Delay disc. indifference point, 4s delay0.10.10.30.40.40.40.40.10.60.60.0-0.5-0.00.30.10.0-0.00.10.10.20.4-0.10.30.20.3-0.50.5-0.20.50.2
Delay disc. indifference point, 8s delay0.30.41.00.70.80.70.8-0.30.40.80.5-0.70.50.70.60.50.40.50.50.60.80.20.60.60.6-0.60.6-0.70.7-1.0
Indifference point function ln k0.20.31.1-0.7-1.0-0.8-1.00.2-1.0-0.7-0.50.7-0.4-0.5-0.4-0.4-0.3-0.2-0.4-0.4-0.1-0.2-0.4-0.4-0.20.5-0.50.4-0.30.5
Indifference point function log k0.20.31.1-0.7-1.0-0.8-1.00.2-1.0-0.7-0.50.7-0.4-0.5-0.4-0.4-0.3-0.2-0.4-0.4-0.1-0.2-0.4-0.4-0.20.5-0.50.4-0.30.5
Patch foraging total patch changes 0 sec0.30.51.30.90.91.00.9-0.51.11.10.3-0.90.60.80.60.30.60.50.70.60.60.60.60.50.6-0.70.7-0.50.6-0.0
Patch foraging total patch changes 12 sec1.51.92.91.51.71.61.7-1.41.51.71.2-1.51.31.41.31.31.41.21.31.41.21.31.41.31.1-1.31.3-1.31.2-1.1
Patch foraging total patch changes 18 sec1.21.85.71.61.91.91.9-1.02.41.80.9-1.61.21.41.10.81.00.91.41.11.10.91.11.01.0-1.31.3-1.01.1-0.3
Patch foraging total patch changes 24 sec0.20.42.40.70.90.80.9-0.21.60.90.3-0.70.50.60.40.20.40.20.70.30.40.30.30.20.3-0.60.6-0.20.40.4
Patch foraging total patch changes 6 sec1.32.13.61.71.81.81.8-1.21.81.91.1-1.91.31.61.31.11.21.21.31.41.21.21.41.41.1-1.41.4-1.41.2-0.9
Patch foraging time to switch 0 sec0.10.32.7-0.6-0.7-0.6-0.70.4-1.6-0.60.00.3-0.5-0.5-0.20.1-0.2-0.1-0.8-0.1-0.4-0.2-0.10.0-0.40.5-0.5-0.1-0.3-1.0
Patch foraging water rate 0 sec0.91.84.51.41.81.51.8-1.32.11.50.9-1.41.31.51.20.91.31.11.51.21.31.31.21.11.4-1.41.4-1.11.1-0.4
Patch foraging water rate 12 sec0.20.50.80.70.90.70.9-0.70.80.60.7-0.60.70.80.70.70.60.70.70.70.80.70.70.70.7-0.60.6-0.70.5-0.6
Patch foraging water rate 18 sec0.50.71.0-1.0-0.9-1.0-0.90.7-0.7-1.0-1.00.9-0.8-0.8-0.9-0.9-0.9-0.8-0.7-0.9-0.8-0.8-0.9-0.9-0.70.7-0.70.9-0.90.8
Patch foraging water rate 24 sec0.20.30.50.60.60.50.7-0.60.40.60.3-0.70.40.60.50.30.30.50.30.60.50.40.60.60.5-0.60.6-0.60.4-0.7
Patch foraging water rate 6 sec1.21.72.41.31.41.31.5-1.51.21.21.3-1.31.41.41.41.41.31.41.41.31.41.41.31.31.3-1.21.2-1.31.0-1.1
Seeking ratio, delayed vs. immediate footshock0.00.00.20.1-0.20.0-0.2-0.3-0.40.00.3-0.10.10.00.20.00.20.20.00.10.20.30.20.20.3-0.20.2-0.20.1-0.2
Distance traveled before self-admin3.24.29.32.52.72.82.7-1.83.12.81.5-2.41.72.21.81.51.51.61.81.91.41.61.91.81.6-2.02.0-1.82.0-0.8
Distance traveled after self-admin3.13.86.12.22.42.52.3-1.92.22.41.7-2.31.72.11.91.71.81.81.62.01.61.82.12.01.5-1.91.9-2.01.8-1.1
Extensor digitorum longus weight1.35.26.22.32.22.32.2-2.52.22.32.3-2.32.32.32.32.42.42.42.32.32.42.42.32.32.4-2.42.4-2.22.3-1.1
Bone: elastic displacement0.40.51.90.70.80.70.8-0.50.00.70.6-0.80.40.60.60.70.50.60.10.80.50.40.90.90.5-0.60.6-1.00.8-1.4
Bone: elastic work1.11.52.71.21.31.21.3-1.10.61.21.2-1.40.91.21.21.31.11.20.71.31.11.01.41.41.1-1.21.2-1.51.3-1.6
Bone: endosteal estimation0.00.10.9-0.0-0.0-0.0-0.00.00.6-0.0-0.10.10.0-0.0-0.1-0.1-0.0-0.10.2-0.2-0.00.0-0.2-0.2-0.00.1-0.10.3-0.01.0
Bone: endosteal perimeter0.20.41.70.60.70.60.7-0.71.30.60.5-0.60.60.70.50.40.60.60.80.50.60.70.50.40.6-0.60.6-0.30.60.7
Epididymis fat weight0.10.42.2-0.6-0.5-0.5-0.50.5-1.5-0.6-0.70.3-0.9-0.6-0.5-0.8-0.7-0.5-1.3-0.3-0.5-0.6-0.1-0.1-0.40.4-0.4-0.0-0.5-1.2
Delta time in closed arm before/after self-admin0.00.00.1-0.10.20.10.2-0.30.3-0.10.10.00.10.10.10.10.00.10.10.10.2-0.00.10.10.10.1-0.1-0.10.1-0.1
Delta time in open arm before/after self-admin1.81.73.01.41.21.31.2-1.51.71.41.5-1.41.41.41.31.51.51.41.51.21.31.41.21.10.9-1.41.4-1.01.10.2
Diff in mean of infusions in LGA sessions0.10.10.60.0-0.2-0.0-0.10.2-0.8-0.1-0.2-0.2-0.5-0.2-0.2-0.1-0.3-0.2-0.70.0-0.3-0.30.10.1-0.30.2-0.2-0.2-0.3-0.7
Delay discount exponential model param0.10.10.5-0.5-0.5-0.5-0.50.1-0.3-0.70.00.5-0.1-0.3-0.20.00.0-0.1-0.1-0.2-0.40.1-0.3-0.2-0.30.4-0.40.3-0.50.5
Extinction: sum of active levers before priming0.20.20.80.60.50.80.5-0.20.00.80.4-0.70.10.30.30.20.00.2-0.00.40.30.00.50.50.2-0.40.4-0.50.3-0.9
Active lever presses in extinction session 60.10.10.5-0.2-0.3-0.2-0.30.7-0.5-0.2-0.50.1-0.5-0.4-0.4-0.4-0.5-0.4-0.6-0.3-0.5-0.5-0.3-0.3-0.50.3-0.30.2-0.20.0
Bone: final force2.13.34.01.81.81.81.8-1.91.11.81.7-1.91.71.81.91.81.91.91.51.91.91.92.02.01.9-1.81.8-2.01.7-1.9
Bone: final moment1.62.53.11.51.61.51.6-1.71.01.61.5-1.61.51.61.61.61.61.71.31.71.61.61.71.71.6-1.61.6-1.81.5-1.7
Food consumed during 24 hour testing period1.92.63.41.61.41.61.4-1.60.91.61.8-1.61.71.61.71.71.71.71.51.71.61.71.71.71.6-1.71.7-1.71.7-1.4
Glucose2.13.33.81.81.81.81.8-1.91.61.81.7-1.91.71.91.81.81.81.91.71.92.01.81.91.92.0-1.91.9-1.81.9-1.0
Heart weight0.20.30.70.20.40.30.5-0.5-0.00.30.8-0.40.60.50.60.70.70.70.50.60.80.70.60.70.7-0.50.5-0.70.3-0.8
Delay discount hyperbolic model param0.30.41.0-0.8-0.7-0.8-0.70.5-0.6-1.0-0.40.8-0.5-0.6-0.5-0.3-0.3-0.4-0.5-0.5-0.7-0.2-0.6-0.5-0.70.7-0.70.6-0.80.5
Intermittent access intake day 1-15 change0.10.20.60.0-0.0-0.1-0.0-0.8-0.4-0.10.60.10.50.10.40.60.50.50.40.30.40.50.30.30.4-0.20.2-0.3-0.3-0.7
Intermittent access intake escalation0.10.10.5-0.1-0.1-0.2-0.1-0.7-0.5-0.20.50.20.40.00.30.60.40.40.30.20.30.50.20.30.3-0.00.0-0.2-0.4-0.6
Intermittent access intake escalation 20.20.30.9-0.7-0.6-0.8-0.6-0.6-0.7-0.80.50.80.3-0.40.10.70.30.20.3-0.1-0.20.4-0.2-0.1-0.30.5-0.50.2-1.0-0.1
Intermitt. access day 1 inactive lever presses0.00.10.30.20.10.00.10.50.50.0-0.4-0.2-0.10.1-0.1-0.3-0.4-0.2-0.0-0.10.1-0.4-0.1-0.10.3-0.40.40.10.20.5
Intermitt. access day 15 inactive lever presses0.20.40.90.70.80.70.8-0.81.00.60.5-0.60.70.70.60.60.60.50.70.60.60.50.50.50.8-0.90.9-0.50.5-0.2
Intermitt. access escalation Index0.10.10.40.30.20.20.3-0.50.60.30.4-0.30.20.20.20.30.30.20.30.20.10.30.20.20.2-0.00.0-0.10.40.5
Intermittent access day 1 total infusions3.86.17.22.72.62.72.6-2.51.92.62.6-2.72.32.52.62.52.52.52.12.62.42.42.62.72.2-2.32.3-2.72.3-2.3
Intermittent access day 15 total infusions2.13.14.81.71.61.61.6-2.20.91.62.2-1.61.81.61.92.11.92.01.61.91.81.91.92.01.6-1.51.5-2.01.3-2.0
Intermittent access terminal intake (last 3 days)3.14.17.31.81.81.71.8-2.51.11.72.7-1.72.21.82.32.72.42.31.92.22.02.42.22.21.7-1.71.7-2.21.2-1.9
Intermittent access total infusions4.55.38.12.22.12.12.0-2.81.32.12.8-2.12.42.22.52.82.62.62.22.52.42.52.42.52.1-1.81.8-2.51.8-2.2
Intermittent access day 1 locomotion4.86.17.52.72.72.72.6-2.52.62.72.6-2.52.52.52.52.52.62.52.52.52.32.42.52.42.2-2.42.4-2.42.5-1.3
Intermittent access day 15 total locomotion2.13.75.32.22.22.22.2-1.91.92.11.9-2.31.62.01.91.71.71.91.52.01.61.72.12.12.0-1.91.9-2.11.8-1.6
Intermittent access total locomotion6.67.910.43.23.23.23.2-2.62.83.22.7-3.12.63.02.82.52.72.72.52.92.62.52.92.92.6-2.92.9-2.92.6-2.2
Intermittent access standard deviation1.02.14.91.10.91.00.9-2.00.31.02.1-0.91.81.11.72.21.91.71.61.51.51.91.41.51.2-1.11.1-1.50.8-1.4
Left kidney weight0.00.20.50.40.50.30.5-0.50.70.30.5-0.20.60.50.50.60.50.50.70.40.50.50.30.30.3-0.30.3-0.30.30.0
Right kidney weight0.21.11.91.00.90.90.9-1.31.20.91.2-0.81.31.01.11.21.21.11.41.01.11.20.90.90.8-1.01.0-0.80.9-0.1
Cocaine induced anxiety1.31.93.81.31.21.21.2-1.51.51.31.7-1.01.81.41.51.71.51.52.01.21.61.51.11.11.6-1.21.2-1.01.4-0.1
Post-drug Anxiety0.90.92.30.70.70.70.7-1.20.90.71.3-0.41.40.91.11.31.21.11.50.81.31.20.70.71.1-0.70.7-0.60.8-0.2
Baseline Anxiety1.51.72.4-1.2-1.2-1.2-1.11.3-1.0-1.2-1.51.2-1.5-1.3-1.4-1.6-1.3-1.4-1.4-1.3-1.5-1.3-1.3-1.3-1.51.3-1.31.3-1.30.8
Tail length7.428.838.55.45.35.35.2-5.33.05.35.4-5.65.15.35.55.35.35.54.45.75.55.35.75.85.3-5.45.4-5.95.3-6.2
Length with tail5.825.331.65.15.05.05.0-5.03.05.15.0-5.24.85.05.25.05.15.24.25.45.15.15.45.45.0-5.05.0-5.54.8-5.6
Length without tail0.92.83.51.71.81.71.7-1.71.91.71.6-1.61.71.71.71.71.81.61.81.61.71.81.61.51.8-1.71.7-1.51.6-0.7
Times rat made contact with spout0.20.20.70.40.60.40.6-0.50.90.40.6-0.30.60.40.40.60.40.30.70.30.30.40.30.20.3-0.30.3-0.20.40.1
Lifetime Intake3.03.66.01.81.71.71.7-2.40.81.72.5-1.62.01.72.12.42.12.21.82.12.02.12.02.11.8-1.41.4-2.11.4-2.2
Liver weight, left2.13.46.11.71.91.71.9-1.90.91.71.7-1.71.71.81.91.82.01.91.42.01.91.92.02.01.9-1.91.9-2.11.9-2.5
Liver weight, right1.52.63.71.61.61.51.6-1.50.91.61.7-1.61.51.61.61.71.51.71.31.71.61.51.71.71.6-1.71.7-1.81.8-1.9
Locomotor activity0.40.61.4-0.6-0.4-0.5-0.41.0-0.2-0.5-1.20.6-0.9-0.6-0.9-1.1-1.1-0.9-0.9-0.8-0.8-1.0-0.7-0.8-0.80.8-0.80.8-0.70.6
Locomotor testing distance0.10.11.3-0.1-0.1-0.1-0.10.10.60.1-0.30.30.0-0.1-0.2-0.2-0.2-0.20.3-0.3-0.1-0.1-0.3-0.4-0.20.2-0.20.5-0.11.1
Locomotor testing rearing0.20.41.5-0.5-0.6-0.5-0.50.60.1-0.3-0.80.7-0.5-0.6-0.7-0.7-0.7-0.7-0.3-0.7-0.6-0.6-0.8-0.8-0.60.6-0.60.8-0.71.2
Locomotion in novel chamber0.10.22.3-0.00.10.10.10.31.10.0-0.30.10.00.0-0.2-0.3-0.2-0.30.3-0.3-0.0-0.3-0.4-0.40.1-0.30.30.50.21.5
Locomotion in novel chamber post-restriction1.72.87.61.82.11.82.1-1.52.81.81.2-1.91.51.91.41.01.41.41.71.41.71.41.51.31.7-1.81.8-1.31.90.2
Fecal boli incidents, locomotor time 10.60.81.50.60.80.70.8-1.20.70.71.1-0.71.00.91.01.01.21.10.91.01.01.21.01.10.9-0.50.5-1.00.5-0.6
Change in fecal boli incidents, locomotor task0.40.41.7-0.1-0.2-0.2-0.20.90.5-0.1-1.00.2-0.7-0.3-0.7-0.9-1.0-0.8-0.4-0.7-0.3-0.9-0.7-0.8-0.30.1-0.10.80.11.3
Time >=10cm from walls, locomotor time 10.20.20.50.50.40.50.40.00.70.50.4-0.50.40.50.40.30.30.40.50.30.40.40.40.30.3-0.50.5-0.30.40.2
Bouts of movement, locomotor time 10.50.52.4-0.5-0.2-0.4-0.20.8-1.3-0.5-0.60.3-0.9-0.5-0.6-0.7-0.7-0.7-1.2-0.3-1.1-0.8-0.3-0.2-1.00.6-0.60.0-0.7-1.6
Total resting periods, locomotor time 10.40.43.5-0.20.0-0.20.00.6-1.2-0.3-0.4-0.0-0.7-0.3-0.3-0.5-0.5-0.4-1.2-0.0-0.9-0.60.00.1-0.80.4-0.4-0.3-0.5-1.9
Rest time, locomotor task time 11.11.45.81.31.51.31.5-0.80.31.20.7-1.60.41.21.00.80.71.0-0.01.30.70.61.51.50.7-1.01.0-1.71.0-2.4
Distance moved, locomotor task time 10.30.53.3-0.7-1.1-0.6-1.10.4-0.2-0.6-0.30.9-0.1-0.6-0.5-0.2-0.4-0.50.2-0.8-0.5-0.3-0.9-0.9-0.30.5-0.51.0-0.61.8
Vertical activity count, locomotor time 10.10.22.10.0-0.4-0.0-0.4-0.20.40.10.30.20.40.00.10.30.30.20.7-0.10.20.3-0.2-0.20.3-0.20.20.40.11.4
Time >=10cm from walls, locomotor time 22.13.03.91.61.61.71.6-1.61.61.71.9-1.61.81.81.82.01.91.91.81.81.91.81.81.81.9-1.61.6-1.71.9-0.8
Bouts of movement, locomotor time 20.00.00.3-0.10.20.00.20.2-0.0-0.10.30.10.0-0.10.10.10.20.1-0.10.1-0.40.00.10.2-0.30.0-0.0-0.2-0.1-0.6
Total resting periods, locomotor time 20.10.10.5-0.40.0-0.30.00.5-0.3-0.4-0.10.3-0.4-0.3-0.2-0.2-0.2-0.3-0.5-0.1-0.7-0.3-0.2-0.1-0.60.3-0.30.0-0.4-0.6
Rest time, locomotor task time 20.60.82.4-0.6-0.3-0.6-0.31.3-1.1-0.7-1.10.4-1.2-0.7-0.9-1.1-1.2-1.0-1.6-0.6-0.9-1.3-0.5-0.5-0.80.7-0.70.3-0.6-1.1
Distance moved, locomotor task time 20.60.71.30.80.40.80.4-1.00.90.80.9-0.71.00.80.80.90.90.81.10.70.80.90.60.60.9-1.01.0-0.50.90.5
Vertical activity count, locomotor time 20.10.11.00.1-0.40.1-0.4-0.40.10.10.4-0.00.50.10.30.40.40.40.60.10.30.50.00.00.3-0.30.30.10.31.0
Light reinforcement 10.30.83.11.31.11.21.0-0.71.81.20.6-1.10.91.00.70.60.50.61.10.70.60.50.70.60.6-1.01.0-0.50.80.6
Light reinforcement 20.10.10.7-0.2-0.3-0.2-0.30.10.2-0.3-0.30.4-0.0-0.3-0.3-0.4-0.2-0.30.2-0.4-0.4-0.2-0.5-0.5-0.40.4-0.40.6-0.60.8
Bone: marrow area0.00.11.1-0.1-0.1-0.1-0.10.10.6-0.1-0.20.2-0.0-0.1-0.2-0.2-0.1-0.20.2-0.3-0.1-0.1-0.3-0.3-0.10.1-0.10.4-0.11.1
Bone: maximum diameter0.40.71.60.90.90.90.9-1.01.30.90.7-0.80.90.90.80.70.90.81.10.70.91.00.70.70.9-0.90.9-0.60.80.2
Bone: maximum force0.61.11.51.01.01.01.0-1.20.61.00.9-1.11.01.11.11.01.11.10.91.11.11.21.21.21.1-1.11.1-1.21.0-1.1
Bone: maximum moment0.30.60.70.70.70.70.7-0.90.50.70.6-0.80.70.80.70.70.80.80.60.80.80.80.80.80.8-0.80.8-0.80.7-0.7
Mean time between licks in bursts0.20.50.8-0.9-0.7-0.9-0.70.7-0.8-0.9-0.80.8-0.8-0.7-0.7-0.9-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.6-0.70.7-0.70.6-0.80.2
Mean num. licks in bursts1.21.82.7-1.3-1.1-1.3-1.11.4-0.6-1.3-1.61.3-1.4-1.3-1.5-1.6-1.4-1.5-1.3-1.4-1.4-1.4-1.4-1.5-1.41.4-1.41.4-1.21.4
Cd content in liver2.32.53.41.71.81.71.8-1.51.31.71.4-1.81.31.61.61.61.51.61.11.71.51.51.81.81.5-1.51.5-1.81.7-1.6
Co content in liver0.00.00.2-0.00.0-0.00.1-0.0-0.3-0.00.1-0.1-0.10.00.10.10.00.1-0.20.10.00.00.20.20.00.1-0.1-0.2-0.0-0.4
Cu content in liver0.20.20.4-0.4-0.4-0.4-0.40.5-0.1-0.4-0.30.5-0.3-0.4-0.4-0.2-0.5-0.4-0.2-0.5-0.5-0.5-0.5-0.5-0.50.5-0.50.5-0.40.6
Fe content in liver3.64.45.8-2.1-2.2-2.1-2.22.1-1.2-2.1-2.22.2-1.9-2.1-2.1-2.1-2.1-2.2-1.6-2.2-2.1-2.1-2.3-2.3-2.12.1-2.12.3-2.12.4
K content in liver1.01.01.4-1.1-1.1-1.1-1.11.0-0.9-1.1-0.91.2-0.9-1.0-1.0-1.0-1.0-1.0-0.8-1.0-1.0-1.0-1.1-1.0-1.01.0-1.01.0-1.10.6
Mg content in liver0.70.71.00.80.80.80.8-0.90.40.81.0-0.80.80.80.90.90.90.90.70.90.90.90.90.90.9-0.90.9-1.00.8-1.0
Mn content in liver1.92.12.51.41.41.41.4-1.51.11.31.6-1.41.51.51.51.51.51.51.41.51.51.51.51.51.5-1.51.5-1.51.4-1.1
Na content in liver1.61.73.0-1.4-1.4-1.4-1.41.2-0.7-1.3-1.21.6-1.0-1.3-1.3-1.2-1.2-1.3-0.8-1.4-1.2-1.2-1.5-1.5-1.21.3-1.31.6-1.41.7
Rb content in liver1.01.21.41.11.11.11.1-1.10.81.11.2-1.11.11.11.11.11.11.11.01.11.11.11.11.11.1-1.21.2-1.11.1-1.0
Se content in liver0.60.71.7-0.9-0.9-0.9-0.90.8-1.3-1.0-0.80.8-1.0-0.9-0.8-0.7-0.8-0.7-1.1-0.7-0.8-0.8-0.6-0.6-0.80.9-0.90.5-0.9-0.1
Sr content in liver1.00.81.00.90.90.90.9-1.00.80.91.0-0.90.90.91.01.01.01.00.91.01.01.01.01.01.0-0.90.9-1.00.9-0.6
Zn content in liver0.40.51.0-0.7-0.6-0.7-0.60.8-0.9-0.7-0.70.5-0.9-0.7-0.7-0.7-0.8-0.7-1.0-0.6-0.8-0.8-0.5-0.5-0.80.7-0.70.4-0.7-0.1
Bone: minimum diameter0.20.31.50.50.50.50.5-0.51.20.50.4-0.30.70.50.40.40.50.40.90.30.50.50.20.20.5-0.50.5-0.10.50.9
Time in familiar zone, hab. session 10.40.42.0-0.5-0.5-0.5-0.50.50.3-0.5-0.50.7-0.3-0.5-0.6-0.4-0.7-0.7-0.0-0.7-0.5-0.6-0.8-0.9-0.50.5-0.50.9-0.51.4
Time in novel zone, hab. session 10.20.20.4-0.4-0.5-0.4-0.50.5-0.6-0.5-0.40.4-0.6-0.5-0.4-0.4-0.4-0.4-0.6-0.4-0.5-0.4-0.3-0.3-0.50.5-0.50.3-0.50.2
Total zone transitions, hab. session 13.44.78.82.42.42.42.4-2.23.02.41.9-2.22.22.32.11.92.12.02.52.02.22.11.91.92.2-2.32.3-1.82.3-0.3
Total locomotion distance, hab. session 10.60.94.31.01.21.01.2-0.82.11.00.6-0.71.01.00.70.70.80.61.30.60.80.80.50.40.8-0.90.9-0.30.80.8
Locomotion velocity, hab. session 10.81.24.31.21.41.21.4-1.02.11.20.7-0.91.21.20.90.91.10.91.40.81.01.00.70.71.0-1.11.1-0.61.00.4
Time in familiar zone, hab. session 20.60.63.4-0.6-0.6-0.6-0.60.50.4-0.6-0.60.9-0.3-0.6-0.7-0.5-0.7-0.70.0-0.9-0.5-0.7-1.0-1.0-0.70.6-0.61.1-0.71.8
Time in novel zone, hab. session 20.30.31.60.60.40.60.4-0.4-0.20.50.5-0.70.30.50.60.40.60.60.00.70.40.50.80.80.5-0.50.5-0.90.5-1.3
Total zone transitions, hab. session 23.34.27.42.22.12.22.1-2.12.72.21.9-2.12.12.22.01.92.12.02.31.92.12.11.91.82.1-2.12.1-1.72.2-0.1
Total locomotion distance, hab. session 20.50.64.30.80.80.80.8-0.62.10.80.4-0.70.70.70.50.50.70.51.10.30.60.60.30.20.6-0.70.7-0.10.51.6
Locomotion velocity, hab. session 20.20.33.20.40.50.40.5-0.31.80.40.1-0.30.30.40.10.10.30.10.8-0.00.30.3-0.0-0.10.2-0.30.30.30.21.8
Novel to familiar place preference ratio2.52.84.2-1.9-1.8-1.9-1.81.6-2.1-1.9-1.51.8-1.7-1.8-1.6-1.5-1.5-1.6-1.8-1.6-1.7-1.6-1.6-1.5-1.71.7-1.71.5-1.60.5
Novelty place preference2.83.05.2-1.9-1.9-1.9-1.91.7-2.3-2.0-1.51.8-1.8-1.8-1.7-1.6-1.6-1.6-1.9-1.6-1.8-1.7-1.6-1.5-1.81.8-1.81.4-1.70.3
Time in novel zone, NPP test2.12.24.4-1.7-1.7-1.7-1.71.5-2.1-1.7-1.31.5-1.5-1.6-1.4-1.3-1.4-1.4-1.7-1.3-1.6-1.4-1.3-1.2-1.51.5-1.51.2-1.40.1
Total zone transitions, NPP test2.23.24.42.02.02.02.0-1.82.12.01.5-2.01.81.91.71.51.71.71.81.71.81.81.71.71.9-1.91.9-1.61.9-0.8
Total locomotion distance, NPP test1.62.16.21.71.61.71.6-1.42.51.71.1-1.51.51.61.31.21.41.21.81.21.41.41.21.11.4-1.51.5-1.01.40.4
Locomotion velocity, NPP test1.11.55.21.51.41.51.4-1.12.31.40.9-1.31.21.31.10.91.11.01.51.01.21.11.00.91.2-1.21.2-0.81.10.5
Intraocular pressure0.00.00.20.00.30.00.3-0.00.0-0.10.2-0.10.00.10.20.20.30.2-0.10.2-0.10.20.30.30.30.1-0.1-0.3-0.1-0.4
Delta distance traveled before/after self-admin0.20.20.40.30.30.30.2-0.2-0.00.10.5-0.50.40.40.50.50.60.60.20.60.50.50.60.60.4-0.40.4-0.60.4-0.5
Delta ambulatory time before/after self-admin0.10.10.5-0.4-0.3-0.4-0.40.4-0.7-0.5-0.10.2-0.2-0.2-0.1-0.1-0.0-0.0-0.4-0.0-0.1-0.10.00.1-0.10.2-0.2-0.1-0.3-0.3
Parametrial fat weight0.92.15.5-1.8-1.6-1.8-1.61.2-2.4-1.9-0.91.5-1.4-1.4-1.2-0.9-1.3-1.1-1.6-1.1-1.1-1.3-1.1-1.0-1.51.8-1.80.9-1.7-0.4
Pavlov. Cond. lever latency0.50.73.4-0.8-0.7-0.8-0.80.9-1.8-0.7-0.50.4-1.1-0.8-0.6-0.5-0.9-0.6-1.5-0.4-0.8-0.8-0.2-0.2-0.80.8-0.80.0-0.8-1.1
Pavlov. Cond. magazine entry latency0.10.10.40.40.40.40.4-0.30.60.40.4-0.40.40.40.40.50.30.30.50.30.40.30.30.30.3-0.30.3-0.30.40.1
Pavlov. Cond. change in total contacts0.10.10.70.20.20.20.2-0.30.80.20.2-0.00.40.20.20.30.30.20.60.10.20.2-0.0-0.00.2-0.20.20.10.20.6
Pavlov. Cond. index score0.40.52.10.70.70.70.7-0.71.40.70.6-0.50.90.70.60.60.70.61.20.40.70.70.40.30.7-0.70.7-0.20.70.6
Pavlov. Cond. latency score0.40.52.30.70.60.70.6-0.71.50.60.5-0.30.90.60.50.50.70.51.20.30.70.60.20.20.6-0.60.6-0.00.61.0
Pavlov. Cond. lever contacts0.80.93.90.90.90.90.9-1.02.00.90.7-0.61.31.00.80.71.00.81.60.61.01.00.40.41.0-0.90.9-0.20.91.0
Pavlov. Cond. magazine entry number0.40.50.6-0.7-0.6-0.7-0.70.7-0.6-0.7-0.70.7-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.6-0.60.7-0.70.4
Pavlov. Cond. intertrial magazine entries0.20.30.40.40.50.40.5-0.50.30.40.6-0.50.50.50.60.50.60.60.40.60.50.60.60.60.5-0.60.6-0.60.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.90.70.60.70.6-0.61.40.60.5-0.40.80.60.60.50.60.51.10.40.70.60.30.20.6-0.60.6-0.10.70.7
Pavlov. Cond. response bias0.50.70.90.90.90.90.9-0.80.90.90.8-0.80.90.90.80.80.80.80.90.80.90.80.80.70.9-0.80.8-0.70.9-0.4
Pavlov. Cond. lever latency1.82.54.1-1.5-1.7-1.5-1.71.6-2.0-1.5-1.71.4-1.8-1.6-1.6-1.7-1.7-1.6-1.9-1.5-1.6-1.6-1.4-1.4-1.61.5-1.51.3-1.60.3
Pavlov. Cond. magazine entry latency0.10.10.5-0.4-0.2-0.4-0.20.5-0.4-0.5-0.20.2-0.5-0.4-0.3-0.3-0.4-0.3-0.7-0.2-0.5-0.4-0.2-0.1-0.40.5-0.50.1-0.4-0.3
Pavlov. Cond. change in total contacts0.50.92.60.81.00.81.0-0.91.60.81.2-0.61.20.90.91.11.00.91.40.70.90.90.60.60.9-0.70.7-0.60.80.2
Pavlov. Cond. index score0.71.01.70.91.10.91.1-1.01.30.91.1-0.91.11.01.01.01.01.01.10.91.01.00.90.91.0-0.90.9-0.80.9-0.2
Pavlov. Cond. latency score1.11.42.31.11.41.11.4-1.11.51.11.3-1.11.31.21.21.21.21.21.31.11.21.21.11.11.2-1.11.1-1.11.2-0.5
Pavlov. Cond. lever contacts1.82.54.61.51.61.51.6-1.62.21.51.8-1.41.81.61.61.81.71.62.01.41.61.61.31.31.6-1.51.5-1.21.5-0.0
Pavlov. Cond. magazine entry number0.10.10.3-0.2-0.5-0.2-0.50.1-0.2-0.1-0.30.4-0.1-0.2-0.3-0.2-0.3-0.30.0-0.4-0.2-0.3-0.4-0.4-0.20.1-0.10.5-0.20.5
Pavlov. Cond. intertrial magazine entries0.00.00.20.2-0.10.2-0.1-0.10.10.20.2-0.00.30.10.10.30.00.10.4-0.00.10.0-0.1-0.10.1-0.20.20.10.10.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.80.50.70.50.7-0.50.90.40.7-0.40.60.50.60.60.60.50.70.50.50.60.50.50.5-0.40.4-0.40.5-0.0
Pavlov. Cond. response bias0.81.12.21.01.11.01.1-1.11.50.91.3-0.91.31.11.11.21.21.11.41.01.11.10.90.91.1-1.01.0-0.81.0-0.1
Time in closed arm before self-admin0.10.10.6-0.1-0.4-0.4-0.40.3-0.8-0.4-0.50.0-0.4-0.2-0.3-0.5-0.3-0.2-0.5-0.20.1-0.2-0.1-0.10.2-0.10.10.0-0.0-0.4
Time in closed arm after self-admin0.10.10.50.20.20.10.2-0.6-0.10.00.1-0.30.10.30.30.10.30.40.00.40.70.30.50.50.6-0.40.4-0.50.4-0.6
Time in open arm before self-admin0.70.81.5-1.0-0.9-0.8-0.91.2-0.8-0.8-0.70.9-0.9-1.1-0.9-0.7-0.9-0.9-0.9-0.9-1.2-1.0-0.9-0.9-0.90.9-0.90.8-0.70.6
Time in open arm after self-admin0.20.20.60.30.40.60.4-0.30.70.70.7-0.40.60.40.50.80.60.40.60.40.10.50.40.30.2-0.30.3-0.30.30.4
Bone: periosteal estimation0.81.82.81.41.41.41.4-1.41.71.41.2-1.31.41.41.31.21.41.31.51.21.41.41.21.21.4-1.41.4-1.11.4-0.2
Bone: periosteal perimeter0.30.51.60.70.80.70.8-0.81.30.70.5-0.70.80.80.70.50.70.61.00.60.80.80.50.50.8-0.80.8-0.40.70.4
Bone: post-yield work0.10.20.4-0.4-0.5-0.4-0.50.4-0.3-0.4-0.60.4-0.4-0.4-0.5-0.6-0.5-0.5-0.4-0.5-0.4-0.4-0.5-0.5-0.40.4-0.40.5-0.50.5
Progressive ratio test 1 active lever presses5.26.47.92.62.52.62.5-2.72.02.62.8-2.62.52.62.72.72.52.72.42.72.52.52.62.72.4-2.52.5-2.72.4-2.1
Progressive ratio test 1 breakpoint5.16.37.82.62.52.62.5-2.62.02.52.8-2.62.52.52.62.72.52.62.42.62.52.52.62.62.4-2.42.4-2.62.4-2.0
Progressive ratio test 1 inactive lever presses0.20.30.60.40.40.30.4-0.60.20.30.7-0.40.60.50.60.60.60.60.60.50.80.50.50.50.7-0.60.6-0.50.4-0.5
Progressive ratio test 2 active lever presses4.65.37.32.32.32.32.2-2.71.42.22.7-2.32.32.22.52.62.42.52.02.52.22.32.52.52.4-2.02.0-2.51.9-2.3
Progressive ratio test 2 breakpoint4.34.96.72.32.22.22.1-2.51.32.12.6-2.32.12.12.32.52.22.31.92.42.12.22.42.42.2-1.91.9-2.41.8-2.3
Progressive ratio test 2 inactive lever presses6.310.312.63.33.33.33.3-3.42.83.23.4-3.13.33.23.33.43.23.33.23.33.43.23.23.23.6-3.03.0-3.22.7-2.5
Incentive Sensitization - Responses1.42.02.81.61.61.51.6-1.41.21.51.4-1.71.21.41.41.41.31.41.11.51.21.21.51.51.7-1.21.2-1.51.2-1.3
Incentive Sensitization - Breakpoint1.31.72.51.51.51.41.5-1.41.01.31.3-1.61.11.31.31.31.21.30.91.41.11.11.51.41.6-1.11.1-1.51.0-1.4
Sum of active levers in priming session hrs 5-60.20.21.90.30.20.50.30.5-0.70.5-0.4-0.5-0.6-0.1-0.2-0.3-0.4-0.3-0.90.1-0.6-0.40.20.2-0.30.0-0.0-0.4-0.2-1.4
Progressive ratio0.50.71.1-0.7-0.8-0.7-0.80.9-0.5-0.8-0.90.9-0.8-0.8-0.9-0.9-0.8-0.9-0.6-1.0-0.9-0.8-1.0-1.0-0.71.0-1.01.0-0.90.9
Food seeking constrained by brief footshock0.30.30.7-0.6-0.5-0.6-0.50.5-0.2-0.6-0.70.8-0.4-0.5-0.6-0.8-0.5-0.6-0.3-0.7-0.5-0.5-0.7-0.7-0.60.5-0.50.7-0.60.6
Seeking ratio, punishment vs. effort0.00.00.2-0.4-0.2-0.4-0.2-0.1-0.3-0.2-0.00.3-0.1-0.2-0.1-0.2-0.1-0.0-0.2-0.10.0-0.1-0.00.0-0.20.1-0.1-0.0-0.2-0.1
Retroperitoneal fat weight0.31.46.3-1.4-1.2-1.4-1.10.9-2.5-1.5-0.91.0-1.3-1.2-0.9-0.9-0.9-0.8-1.8-0.7-1.1-0.8-0.6-0.5-1.21.2-1.20.3-1.2-1.5
Reaction time number correct0.40.81.30.90.80.70.8-0.90.90.70.9-0.80.90.90.90.90.90.90.90.91.00.90.80.81.0-1.11.1-0.81.0-0.3
Reaction time mean minus median0.20.50.8-0.6-0.8-0.6-0.80.9-0.6-0.5-0.80.5-0.8-0.7-0.8-0.8-0.8-0.7-0.8-0.7-0.7-0.8-0.7-0.7-0.70.5-0.50.7-0.40.8
Reaction time mean minus median AUC0.40.91.4-0.8-1.0-0.8-1.01.2-0.7-0.8-1.00.7-1.1-1.0-1.0-1.1-1.0-1.0-1.1-1.0-1.0-1.1-0.9-0.9-1.00.8-0.80.9-0.61.2
Reaction time num false alarms1.31.83.51.41.31.41.4-1.31.91.31.5-1.31.41.31.31.51.31.31.61.11.31.41.11.11.4-1.51.5-1.01.50.2
Reaction time num false alarms AUC1.11.73.51.31.31.31.4-1.21.91.31.4-1.21.51.31.31.41.41.21.71.11.31.41.01.01.3-1.51.5-0.91.40.2
Reaction time trials correct on left0.40.81.30.90.80.70.8-0.90.90.70.9-0.80.90.90.90.90.90.90.90.91.00.90.80.81.0-1.11.1-0.81.0-0.3
Reaction time trials on left0.40.81.40.90.80.80.8-0.90.90.70.9-0.81.01.00.90.90.90.91.00.91.00.90.80.81.0-1.21.2-0.81.0-0.2
Reaction time mean2.13.44.3-1.9-1.8-1.9-1.92.1-1.4-1.8-1.81.7-2.0-1.9-1.9-1.8-1.9-1.9-1.9-1.9-1.9-2.0-1.8-1.8-1.91.8-1.81.8-1.71.8
Reaction time mean AUC1.93.03.7-1.8-1.6-1.8-1.71.9-1.0-1.6-1.81.7-1.8-1.7-1.8-1.8-1.8-1.8-1.6-1.8-1.8-1.9-1.7-1.8-1.81.7-1.71.8-1.51.9
Median of all reaction times2.63.74.4-2.1-1.9-2.0-1.92.1-1.4-1.9-1.91.9-2.0-1.9-2.0-1.9-2.0-1.9-1.8-2.0-1.9-2.1-1.9-1.9-2.01.9-1.91.9-1.81.9
Reaction time omissions0.40.61.5-0.5-0.7-0.6-0.70.9-0.2-0.4-1.00.6-0.8-0.7-0.9-0.9-0.9-0.9-0.6-0.9-1.0-0.9-0.9-0.9-0.80.5-0.50.9-0.61.2
Reaction time false alarm rate0.20.20.90.40.50.50.5-0.40.90.50.6-0.40.50.40.40.50.50.30.70.30.30.50.20.20.4-0.40.4-0.10.50.5
Reaction time premature initiation rate0.60.81.8-1.0-0.8-0.9-0.81.0-0.7-0.9-0.60.9-0.9-1.0-0.8-0.6-0.9-0.9-0.8-0.9-1.0-0.9-0.9-0.8-1.31.1-1.10.8-1.20.5
Reaction time premature initiations0.20.30.8-0.7-0.6-0.6-0.60.5-0.5-0.7-0.30.6-0.5-0.6-0.5-0.3-0.5-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.90.6-0.60.5-0.70.3
Std. dev. reaction times0.71.32.0-1.0-1.0-1.0-1.11.4-0.7-0.9-1.30.9-1.4-1.1-1.2-1.4-1.3-1.2-1.3-1.2-1.2-1.4-1.1-1.1-1.21.0-1.01.1-0.81.3
Reaction time trials completed0.40.81.40.90.80.80.8-0.90.90.70.9-0.81.01.00.90.90.90.91.00.91.00.90.80.81.0-1.21.2-0.81.0-0.2
Reaction time trials AUC0.71.42.21.21.11.11.1-1.11.11.01.2-1.21.21.31.21.21.21.21.21.21.31.21.21.11.3-1.51.5-1.11.2-0.5
Run reversals in cocaine runway, females0.20.20.50.30.40.20.4-0.10.40.30.6-0.20.70.50.50.60.50.40.70.30.50.50.20.20.5-0.50.5-0.20.7-0.1
Run reversals in cocaine runway, males0.10.10.30.00.4-0.00.40.10.10.00.2-0.20.00.20.20.10.20.3-0.10.30.20.20.40.40.10.0-0.0-0.40.1-0.5
Latency to leave start box in cocaine runway0.40.51.1-0.6-1.1-0.8-1.10.8-0.9-0.7-0.50.7-0.7-0.8-0.6-0.4-0.7-0.5-0.6-0.7-0.5-0.7-0.6-0.6-0.50.8-0.80.6-0.40.8
Latency to leave start box in cocaine runway, F1.31.53.2-1.2-1.7-1.4-1.71.2-1.8-1.3-0.91.2-1.2-1.4-1.1-0.8-1.1-1.0-1.3-1.1-1.0-1.1-1.0-1.0-1.11.4-1.41.0-1.00.7
Latency to leave start box in cocaine runway, M0.90.81.61.11.01.11.0-0.81.31.10.8-1.00.90.90.90.80.60.81.10.80.80.60.80.81.0-1.01.0-0.71.0-0.1
Std. dev. time between licks in bursts0.10.21.9-0.3-0.3-0.3-0.30.10.6-0.3-0.30.50.1-0.2-0.3-0.3-0.1-0.30.4-0.5-0.1-0.1-0.5-0.6-0.10.1-0.10.7-0.21.4
Total sessions with >9 infusions1.01.22.41.11.01.01.0-1.20.41.11.4-1.01.11.01.21.31.11.20.91.21.01.11.21.21.0-0.80.8-1.21.0-1.6
Short access day 1 total inactive lever presses0.10.20.4-0.5-0.5-0.5-0.5-0.4-0.5-0.60.60.60.6-0.10.30.60.50.50.60.10.50.5-0.00.10.50.3-0.30.0-0.30.2
Short access day 10 total inactive lever presses2.15.26.9-2.6-2.4-2.5-2.42.0-1.6-2.6-2.32.6-2.0-2.2-2.3-2.3-2.2-2.3-1.8-2.4-2.0-2.3-2.5-2.5-1.92.2-2.22.5-2.22.2
Short access day 1 total infusions0.10.20.5-0.3-0.4-0.3-0.40.4-0.6-0.40.10.5-0.2-0.5-0.20.1-0.4-0.2-0.2-0.3-0.5-0.4-0.4-0.3-0.40.7-0.70.3-0.4-0.1
Short access day 10 total infusions2.02.53.71.51.51.51.4-1.81.01.41.9-1.31.81.51.81.81.81.81.61.71.81.81.61.71.6-1.11.1-1.71.2-1.5
Short access total infusions1.31.73.21.21.11.21.1-1.40.41.21.7-1.11.41.21.51.71.41.51.11.41.21.31.41.51.2-0.90.9-1.51.1-1.8
Short access day 1 locomotion0.20.20.80.20.00.2-0.00.90.20.2-0.70.1-0.4-0.2-0.5-0.8-0.7-0.6-0.3-0.4-0.3-0.8-0.4-0.4-0.40.2-0.20.4-0.10.1
Short access day 10 total locomotion1.52.84.61.91.91.91.9-1.62.11.71.8-1.61.81.81.71.61.81.61.91.61.51.61.61.51.4-1.61.6-1.51.7-0.6
Short access total locomotion2.83.45.02.12.12.22.1-1.62.22.11.9-1.91.91.91.91.71.91.82.01.81.71.71.81.71.6-1.91.9-1.71.8-0.8
One hour access (0.3 mA shock)0.60.74.00.30.40.30.3-1.1-0.80.31.3-0.50.70.50.91.30.91.00.31.00.60.91.01.10.3-0.40.4-1.10.0-2.0
Compulsive drug intake1.41.62.8-1.7-1.5-1.5-1.51.1-1.4-1.6-1.01.5-1.2-1.4-1.2-1.0-1.2-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.31.2-1.21.2-1.20.8
One hour access (shock baseline)1.21.93.31.41.21.21.2-1.60.41.21.7-1.41.31.31.51.71.51.51.01.51.31.51.51.61.2-1.11.1-1.60.8-1.8
Social response proportion1.01.21.71.01.20.91.2-1.10.70.91.0-1.10.91.21.11.01.11.20.71.21.21.11.31.31.2-0.90.9-1.30.8-1.3
Social responses0.50.62.20.91.10.91.0-0.61.51.00.5-1.00.60.90.60.50.60.60.80.60.80.60.70.60.8-0.90.9-0.60.70.2
Social time3.24.36.3-2.0-1.6-1.8-1.62.3-1.1-1.7-2.51.9-2.4-2.0-2.3-2.5-2.4-2.4-2.2-2.2-2.2-2.5-2.1-2.1-1.92.0-2.02.1-2.11.7
Soleus weight0.30.92.31.01.01.01.0-1.01.51.00.9-0.81.11.00.90.91.00.91.30.81.01.00.70.71.0-1.11.1-0.61.00.3
Bone: stiffness0.71.11.71.01.01.01.0-1.31.11.00.9-0.91.31.11.11.01.21.11.31.01.21.30.90.91.2-1.11.1-0.91.0-0.4
Tibialis anterior weight1.44.85.52.32.22.32.2-2.21.72.32.2-2.32.12.22.22.32.22.22.02.22.12.22.22.22.1-2.22.2-2.22.4-1.8
Time to tail flick, vehicle, before self-admin0.30.30.60.30.00.2-0.0-0.3-0.40.40.7-0.30.70.40.60.60.60.70.60.50.70.70.50.50.6-0.60.6-0.50.7-0.8
Time to tail flick, vehicle, after self-admin0.91.22.01.11.11.21.2-1.01.41.11.1-1.01.21.11.11.21.01.01.41.00.91.10.90.91.0-1.01.0-0.81.3-0.2
Time to tail flick, test, before self-admin0.20.21.10.30.60.40.6-0.10.10.50.1-0.60.10.40.30.20.30.3-0.10.50.30.20.50.50.2-0.30.3-0.60.1-1.0
Time to tail flick, test, after self-admin2.42.53.4-1.4-1.3-1.4-1.31.8-0.9-1.4-1.71.4-1.7-1.5-1.7-1.8-1.8-1.7-1.6-1.6-1.7-1.8-1.6-1.6-1.81.7-1.71.6-1.81.3
Delta time to tail flick, vehicle, before/after SA1.21.23.41.11.61.31.6-1.21.91.20.9-1.20.91.21.01.00.80.91.01.00.80.91.00.90.8-0.80.8-0.91.0-0.3
Delta time to tail flick, test, before/after SA2.42.53.5-1.5-1.8-1.5-1.81.5-1.0-1.6-1.41.8-1.3-1.6-1.5-1.4-1.5-1.5-1.0-1.7-1.6-1.4-1.8-1.8-1.51.7-1.71.8-1.51.9
Tibia length1.74.612.32.12.12.12.1-2.00.52.12.0-2.41.62.12.12.02.02.21.12.42.02.02.52.62.0-2.02.0-2.72.0-3.5
Ambulatory time before self-admin1.52.37.72.12.12.22.1-1.12.82.30.9-1.91.21.61.20.80.91.01.41.20.91.01.21.11.0-1.61.6-1.11.5-0.0
Ambulatory time after self-admin2.93.45.42.12.22.32.1-1.62.12.21.6-2.21.62.01.81.61.71.71.61.91.51.72.01.91.5-1.81.8-1.91.7-1.1
Bone: tissue strength0.10.10.30.30.40.30.4-0.30.60.30.4-0.30.40.30.30.50.30.30.40.30.30.30.30.30.3-0.30.3-0.20.30.2
Total heroin consumption0.40.41.20.90.50.80.5-0.1-0.10.80.7-1.00.40.50.60.80.40.60.20.80.40.50.80.80.5-0.70.7-0.90.5-1.1
Bone: trabecular number2.13.54.31.91.91.91.9-1.81.81.92.0-2.11.71.91.91.91.81.91.71.91.91.82.01.91.9-1.91.9-1.91.9-1.0
Bone: trabecular spacing0.20.30.5-0.6-0.6-0.6-0.60.5-0.5-0.6-0.70.7-0.4-0.6-0.6-0.6-0.5-0.6-0.4-0.6-0.5-0.5-0.7-0.6-0.50.6-0.60.7-0.60.3
Bone: trabecular thickness2.73.33.71.91.91.91.9-1.81.51.91.8-1.91.71.91.81.81.81.81.61.91.81.81.91.91.8-1.91.9-1.91.9-1.5
Bone: trabecular tissue density0.30.50.8-0.6-0.6-0.6-0.60.7-0.4-0.6-0.90.7-0.7-0.7-0.8-0.9-0.7-0.8-0.6-0.8-0.7-0.7-0.8-0.8-0.70.7-0.70.8-0.70.5
Water consumed over 24 hours2.23.03.51.91.51.91.5-1.91.21.91.9-1.81.81.71.81.81.81.81.71.81.71.81.71.71.7-1.81.8-1.71.8-1.2
Number of responses in last shaping day0.10.10.60.20.20.20.2-0.3-0.00.30.7-0.10.50.20.40.80.40.40.40.3-0.00.40.30.3-0.10.1-0.1-0.3-0.2-0.5