Hub : Genes

Plb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Plb1 0.23 0.15 2.8e-10 0.17 0.18 0.17 0.17 3.1e-09 9.1e-10 1.7e-09 2.6e-09
2 LHb gene expression Plb1 0.17 0.15 3.0e-03 0.06 0.03 0.05 0.03 2.0e-02 6.0e-02 2.6e-02 6.9e-02
3 PL intron excision ratio chr6_24090778_24097763 0.06 0.06 2.6e-06 0.05 0.05 0.03 0.04 8.1e-06 4.2e-06 1.1e-04 1.0e-05
4 BLA isoform ratio XM_039111766.1 0.18 0.13 2.6e-08 0.13 0.14 0.14 0.13 1.3e-07 5.0e-08 9.5e-08 1.4e-07
5 Brain isoform ratio XM_039111766.1 0.05 0.05 5.4e-04 0.04 0.03 0.04 0.03 1.2e-04 6.0e-04 2.5e-04 3.5e-04
6 NAcc alternative TSS NM_138898.2 0.03 0.03 4.1e-04 0.03 0.03 0.03 0.03 3.7e-04 3.1e-04 3.4e-04 4.9e-04
7 Brain intron excision ratio chr6_24090778_24097763 0.03 0.03 3.4e-03 0.02 0.02 0.02 0.02 8.0e-03 4.3e-03 6.3e-03 8.1e-03
8 Brain intron excision ratio chr6_24090778_24092431 0.03 0.02 3.5e-03 0.02 0.02 0.02 0.02 6.5e-03 5.0e-03 6.5e-03 7.9e-03
9 Brain gene expression Plb1 0.28 0.2 1.1e-12 0.14 0.12 0.13 0.13 9.4e-13 3.0e-11 7.2e-12 3.1e-12
10 PL isoform ratio XM_039111766.1 0.05 0.04 6.4e-06 0.05 0.05 0.05 0.05 3.4e-06 2.5e-06 3.7e-06 3.5e-06
11 BLA alternative TSS NM_138898.2 0.53 0.22 3.8e-08 0.13 0.12 0.12 0.13 1.3e-07 5.3e-07 6.1e-07 1.7e-07
12 NAcc alternative polyA XM_039111764.1 0.02 0.02 7.9e-03 0.01 0.01 -0 0.01 1.2e-02 1.8e-02 8.1e-01 2.3e-02
13 NAcc isoform ratio XM_039111766.1 0.18 0.16 1.0e-11 0.1 0.1 0.09 0.1 3.5e-12 1.7e-11 5.6e-11 6.7e-12
14 BLA alternative TSS XM_039111766.1 0.16 0.16 2.8e-05 0.09 0.08 0.07 0.08 2.4e-05 5.0e-05 7.9e-05 4.7e-05
15 NAcc gene expression Plb1 0.16 0.09 0.0e+00 0.21 0.22 0.21 0.21 1.1e-23 1.5e-24 7.3e-24 1.0e-23
16 PL gene expression Plb1 0.25 0.21 0.0e+00 0.17 0.18 0.17 0.18 1.1e-18 3.6e-19 1.3e-18 5.8e-19
17 BLA intron excision ratio chr6_24090778_24092431 0.08 0.08 2.8e-03 0.04 0.04 0.04 0.04 2.2e-03 2.7e-03 5.4e-03 2.4e-03
18 BLA intron excision ratio chr6_24090778_24097763 0.08 0.08 2.9e-03 0.04 0.04 0.03 0.04 2.3e-03 2.8e-03 8.8e-03 2.5e-03
19 PL intron excision ratio chr6_24090778_24092431 0.08 0.07 6.2e-07 0.06 0.05 0.04 0.05 6.8e-07 1.5e-06 5.3e-05 2.0e-06
20 Adipose gene expression Plb1 0.11 0.14 9.7e-07 0.05 0.05 0.05 0.05 1.3e-06 1.6e-06 1.7e-06 1.5e-06
21 NAcc alternative TSS XM_039111766.1 0.08 0.07 4.3e-08 0.07 0.07 0.07 0.07 2.9e-08 3.3e-08 1.6e-08 1.2e-08
22 pVTA gene expression Plb1 0.13 0.15 5.3e-04 0.07 0.07 0.06 0.07 5.5e-04 6.3e-04 9.8e-04 6.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density5.28.79.43.0-3.0-3.03.0-3.0-3.0-3.03.0-3.03.03.0-3.0-3.0-3.02.92.9-2.82.8-3.02.82.9-3.1
Area under the delay curve1.11.21.61.1-1.1-1.11.1-1.1-1.1-1.11.1-1.21.10.7-1.1-1.1-0.81.11.3-1.11.1-1.11.21.2-1.1
BMI with tail0.41.21.8-1.11.31.1-1.11.11.11.1-1.11.1-1.1-1.21.31.31.1-1.2-1.10.8-0.80.9-1.1-1.20.6
BMI without tail0.30.61.0-0.71.00.6-0.70.90.80.7-0.70.9-0.7-0.91.01.00.8-0.8-0.70.6-0.60.3-0.5-0.90.2
Body weight1.77.27.8-2.72.72.7-2.72.72.72.7-2.72.7-2.7-2.82.82.82.8-2.7-2.62.5-2.52.6-2.7-2.52.5
Weight adjusted by age0.10.20.4-0.40.40.4-0.40.40.40.4-0.40.4-0.4-0.40.40.30.2-0.5-0.50.3-0.30.3-0.3-0.60.3
Bone surface2.34.04.52.0-2.1-2.02.0-2.1-2.0-2.02.0-2.12.02.1-2.1-2.1-2.12.01.9-2.02.0-1.91.92.0-1.7
Bone volume2.54.34.72.1-2.1-2.12.1-2.1-2.1-2.12.1-2.12.12.1-2.2-2.1-2.12.12.0-2.02.0-2.12.02.1-2.0
Breakpoint value in progressive ratio session0.80.91.60.9-0.9-0.91.0-1.0-0.9-0.90.9-1.11.01.3-1.0-1.0-1.30.90.7-0.80.8-0.90.70.8-1.0
Number of licking bursts0.20.30.30.5-0.6-0.50.5-0.6-0.5-0.50.5-0.60.50.6-0.6-0.6-0.60.50.5-0.50.5-0.40.40.5-0.4
Context. condit. distance diff. score0.00.00.3-0.20.10.2-0.20.00.10.2-0.20.1-0.1-0.10.10.10.1-0.1-0.20.3-0.30.5-0.1-0.10.5
Locomotion velocity, session 10.10.10.2-0.30.50.3-0.40.30.40.4-0.40.4-0.3-0.40.40.50.3-0.4-0.40.3-0.30.2-0.4-0.40.2
Locomotion distance, session 12.02.53.21.7-1.6-1.61.6-1.6-1.6-1.61.6-1.61.61.6-1.5-1.6-1.61.61.6-1.51.5-1.81.51.5-1.7
Locomotion velocity, session 20.10.10.2-0.40.40.4-0.40.30.40.4-0.40.3-0.4-0.30.40.40.4-0.4-0.40.4-0.40.5-0.3-0.40.5
Locomotion distance, session 20.00.00.0-0.00.10.0-0.10.10.10.1-0.10.1-0.1-0.10.10.10.1-0.1-0.10.0-0.0-0.1-0.1-0.1-0.1
Locomotion velocity, session 30.30.40.50.6-0.7-0.60.7-0.6-0.7-0.60.7-0.60.70.6-0.7-0.7-0.70.70.6-0.40.4-0.30.70.7-0.7
Locomotion distance, session 30.90.91.21.0-0.9-1.01.0-0.9-1.0-1.01.0-0.91.00.9-0.9-0.9-1.00.91.0-1.01.0-1.10.90.9-1.1
Stereotopy head waving bouts, day 31.31.51.81.2-1.3-1.21.3-1.2-1.3-1.21.3-1.21.31.2-1.3-1.3-1.31.31.2-1.01.0-0.81.31.4-0.9
Stereotopy head waving duration, day 30.00.00.10.1-0.2-0.10.2-0.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.30.30.20.1-0.10.20.30.30.0
Locomotion velocity, session 70.60.71.10.8-0.8-0.80.8-0.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.80.80.8-1.01.0-0.60.80.8-0.8
Locomotion distance, session 70.00.00.2-0.20.10.2-0.1-0.00.10.1-0.10.1-0.1-0.10.10.10.1-0.1-0.20.1-0.10.5-0.2-0.10.3
Stereotopy head waving bouts, day 70.00.00.0-0.00.1-0.0-0.00.10.00.0-0.00.1-0.0-0.10.10.10.0-0.0-0.0-0.20.2-0.10.0-0.0-0.1
Stereotopy head waving duration, day 70.40.50.90.7-0.6-0.70.7-0.6-0.7-0.70.7-0.60.70.6-0.6-0.6-0.70.70.7-0.90.9-0.90.70.7-0.9
Locomotion velocity, session 80.00.00.1-0.10.00.1-0.00.00.00.0-0.00.0-0.0-0.00.10.00.0-0.0-0.10.4-0.40.1-0.1-0.00.0
Locomotion distance, session 80.20.30.50.5-0.6-0.50.5-0.7-0.5-0.50.5-0.60.60.6-0.5-0.6-0.60.60.5-0.50.5-0.40.60.5-0.2
Degree of sensitization distance1.11.11.9-1.11.01.1-1.11.01.11.1-1.11.0-1.1-1.01.01.01.0-1.0-1.11.0-1.01.4-1.1-1.01.2
Degree of sensitization stereotypy0.00.00.1-0.10.30.1-0.20.30.20.2-0.20.3-0.2-0.30.30.30.2-0.2-0.2-0.10.1-0.2-0.2-0.2-0.1
Conditioned locomotion3.54.14.52.0-2.1-2.02.0-2.0-2.0-2.02.0-2.02.12.0-2.1-2.0-2.02.12.1-2.02.0-1.72.12.1-1.7
Cocaine response after cond. corrected1.82.12.61.5-1.3-1.51.4-1.3-1.4-1.51.4-1.31.41.4-1.3-1.4-1.41.41.5-1.51.5-1.61.51.5-1.6
Cocaine response after cond. not corrected3.33.64.01.9-1.8-2.01.9-1.8-1.9-1.91.9-1.81.91.8-1.8-1.8-1.81.92.0-1.91.9-2.02.02.0-1.9
Cocaine response before conditioning0.81.01.31.0-1.0-1.01.0-1.0-1.0-1.01.0-1.01.01.0-1.0-1.0-1.01.01.0-1.11.1-0.91.01.0-0.9
Saline control response0.60.71.30.9-0.8-0.90.9-0.8-0.8-0.90.9-0.80.80.8-0.8-0.8-0.80.80.9-0.90.9-1.10.70.8-1.1
Bone: connectivity density5.28.18.72.9-2.9-2.92.9-2.8-2.9-2.92.9-2.92.92.9-2.9-2.8-2.92.82.8-2.72.7-2.92.72.8-2.9
Bone: cortical apparent density0.50.60.80.8-0.9-0.80.8-0.9-0.8-0.80.8-0.80.80.9-0.9-0.9-0.80.80.8-0.70.7-0.70.80.8-0.7
Bone: cortical area0.40.61.00.8-0.7-0.80.7-0.7-0.7-0.70.7-0.70.70.7-0.8-0.7-0.60.70.8-1.01.0-0.90.70.7-0.7
Bone: cortical porosity1.11.21.31.1-1.1-1.11.1-1.1-1.1-1.11.1-1.11.11.1-1.1-1.1-1.01.11.1-1.11.1-1.11.11.0-1.1
Bone: cortical porosity0.91.01.11.0-1.0-1.01.0-1.0-1.0-1.01.0-1.01.01.0-1.0-1.0-1.01.01.0-1.01.0-1.00.90.9-1.1
Bone: cortical thickness0.00.00.0-0.00.10.0-0.10.10.10.1-0.10.1-0.1-0.10.00.10.1-0.1-0.0-0.20.2-0.2-0.1-0.1-0.1
Bone: cortical thickness1.61.92.51.4-1.4-1.41.4-1.3-1.4-1.41.4-1.31.41.3-1.4-1.3-1.31.41.4-1.61.6-1.41.41.3-1.3
Bone: cortical tissue density0.30.50.60.7-0.7-0.70.7-0.8-0.7-0.70.7-0.70.70.7-0.7-0.7-0.70.70.7-0.50.5-0.50.70.7-0.6
Condit. Reinf. active minus inactive responses0.30.40.8-0.70.70.6-0.60.60.60.6-0.60.6-0.6-0.60.60.70.6-0.6-0.60.4-0.40.9-0.6-0.60.5
Condit. Reinf. active-inactive response ratio0.30.40.5-0.60.70.6-0.60.60.60.6-0.60.7-0.6-0.70.60.70.6-0.6-0.60.4-0.40.7-0.5-0.60.4
Condit. Reinf. active responses0.40.50.80.7-0.6-0.70.7-0.7-0.7-0.70.7-0.70.70.7-0.7-0.6-0.70.70.7-0.90.9-0.40.70.7-0.8
Condit. Reinf. inactive responses1.82.22.31.5-1.5-1.51.5-1.5-1.5-1.51.5-1.51.51.5-1.5-1.5-1.51.51.5-1.31.3-1.31.41.5-1.4
Incentive salience index mean0.10.10.40.3-0.3-0.30.3-0.4-0.3-0.30.3-0.30.40.3-0.4-0.3-0.30.40.3-0.60.6-0.10.30.4-0.5
Condit. Reinf. lever presses1.11.42.11.2-1.1-1.21.2-1.2-1.2-1.21.2-1.11.11.1-1.2-1.1-1.11.11.2-1.51.5-1.21.11.2-1.3
Condit. Reinf. active minus inactive responses4.04.95.32.2-2.2-2.22.3-2.3-2.3-2.32.3-2.32.32.3-2.2-2.3-2.32.32.2-2.12.1-2.02.32.3-2.0
Condit. Reinf. active-inactive response ratio1.01.11.31.0-1.1-1.01.1-1.1-1.1-1.11.1-1.11.11.1-1.1-1.1-1.11.11.0-0.90.9-0.81.11.1-0.7
Condit. Reinf. active responses3.24.44.72.1-2.1-2.12.1-2.1-2.1-2.12.1-2.12.22.1-2.1-2.1-2.12.22.1-2.02.0-1.92.12.2-1.8
Condit. Reinf. inactive responses1.92.42.51.6-1.5-1.61.6-1.5-1.5-1.61.6-1.51.61.5-1.5-1.5-1.51.61.6-1.61.6-1.51.61.6-1.5
Condit. Reinf. lever presses2.12.93.21.7-1.7-1.71.7-1.8-1.7-1.71.7-1.81.71.8-1.7-1.8-1.81.71.7-1.61.6-1.51.71.8-1.4
Condit. Reinf. lever reinforcers received2.73.73.91.9-1.9-1.92.0-2.0-2.0-1.92.0-2.02.02.0-1.9-2.0-2.02.01.9-1.91.9-1.82.02.0-1.7
Conditioned reinforcement - actives0.20.20.30.4-0.4-0.40.4-0.2-0.4-0.40.4-0.20.40.3-0.3-0.4-0.30.40.5-0.40.4-0.40.60.5-0.3
Conditioned reinforcement - inactives1.71.92.41.4-1.5-1.41.4-1.2-1.4-1.41.4-1.31.41.4-1.5-1.4-1.41.41.4-1.31.3-1.41.61.1-1.4
Conditioned locomotion0.20.20.4-0.40.50.4-0.50.60.40.4-0.40.6-0.4-0.50.60.50.5-0.4-0.30.2-0.20.3-0.1-0.40.5
Patch foraging indifference point 0 sec0.30.50.7-0.60.70.6-0.70.80.70.7-0.70.9-0.7-0.70.70.70.7-0.7-0.60.6-0.60.5-0.7-0.60.5
Patch foraging indifference point AUC1.41.62.31.3-1.4-1.21.3-1.4-1.3-1.21.2-1.31.21.3-1.4-1.5-1.41.21.2-1.11.1-1.31.01.0-1.2
Delay disc. indifference point, 0s delay0.60.61.9-0.70.80.7-0.80.70.80.7-0.80.8-0.8-1.40.80.71.3-0.7-0.50.7-0.70.5-0.6-0.60.7
Delay disc. indifference point, 16s delay1.41.41.81.2-1.2-1.21.2-1.2-1.2-1.21.2-1.31.21.1-1.2-1.2-1.11.21.2-1.01.0-1.21.11.2-1.3
Delay disc. indifference point, 2s delay0.00.00.3-0.20.20.2-0.20.20.20.2-0.20.2-0.2-0.50.20.20.5-0.2-0.10.1-0.10.1-0.1-0.20.1
Delay disc. indifference point, 24s delay5.55.36.12.3-2.2-2.42.3-2.2-2.3-2.42.4-2.32.32.3-2.3-2.2-2.32.42.4-2.22.2-2.22.52.5-2.2
Delay disc. indifference point, 4s delay0.10.10.30.4-0.4-0.40.3-0.3-0.4-0.40.4-0.50.3-0.1-0.4-0.4-0.00.40.5-0.30.3-0.50.40.5-0.5
Delay disc. indifference point, 8s delay1.21.21.41.1-1.1-1.11.1-1.1-1.1-1.11.1-1.11.10.8-1.1-1.1-0.91.11.2-1.21.2-1.21.11.1-1.1
Indifference point function ln k0.00.00.1-0.10.20.1-0.10.20.10.1-0.10.2-0.1-0.20.20.20.2-0.00.10.2-0.20.20.20.20.1
Indifference point function log k0.00.00.1-0.10.20.1-0.10.20.10.1-0.10.2-0.1-0.20.20.20.2-0.00.10.2-0.20.20.20.20.1
Patch foraging total patch changes 0 sec0.20.30.5-0.50.50.5-0.50.60.50.5-0.50.7-0.5-0.60.50.50.6-0.6-0.50.4-0.40.3-0.5-0.40.4
Patch foraging total patch changes 12 sec0.70.91.5-0.90.81.0-1.01.01.01.0-1.01.0-1.0-1.00.80.91.0-1.0-1.00.8-0.80.7-1.2-1.00.9
Patch foraging total patch changes 18 sec0.10.10.2-0.20.30.2-0.30.30.30.3-0.30.4-0.3-0.30.30.20.2-0.3-0.30.0-0.0-0.0-0.3-0.40.0
Patch foraging total patch changes 24 sec1.31.62.0-1.31.21.3-1.31.21.31.3-1.31.2-1.3-1.21.11.11.2-1.3-1.31.2-1.21.3-1.4-1.21.4
Patch foraging total patch changes 6 sec0.00.10.2-0.20.20.2-0.20.30.20.2-0.20.3-0.3-0.30.10.20.2-0.3-0.3-0.10.1-0.2-0.4-0.40.0
Patch foraging time to switch 0 sec0.10.20.30.4-0.4-0.40.4-0.4-0.4-0.40.4-0.40.40.3-0.4-0.3-0.20.40.4-0.50.5-0.50.40.4-0.5
Patch foraging water rate 0 sec0.10.10.2-0.30.40.3-0.30.40.30.3-0.30.5-0.3-0.40.40.30.3-0.3-0.30.4-0.40.4-0.3-0.20.4
Patch foraging water rate 12 sec1.62.43.3-1.61.61.5-1.61.71.51.5-1.51.7-1.5-1.61.61.51.5-1.5-1.41.6-1.61.7-1.2-1.11.8
Patch foraging water rate 18 sec0.40.51.1-0.70.80.6-0.70.90.70.7-0.70.9-0.7-1.00.80.81.0-0.6-0.40.6-0.60.7-0.5-0.20.8
Patch foraging water rate 24 sec1.92.73.3-1.71.81.7-1.61.51.71.7-1.71.5-1.6-1.51.81.71.4-1.7-1.81.7-1.71.7-1.7-1.71.6
Patch foraging water rate 6 sec1.42.02.6-1.51.61.4-1.41.41.41.4-1.41.4-1.4-1.41.61.51.4-1.4-1.31.4-1.41.5-1.2-1.11.5
Seeking ratio, delayed vs. immediate footshock0.30.40.6-0.60.50.6-0.60.50.60.6-0.60.6-0.6-0.50.60.60.7-0.6-0.70.5-0.50.5-0.8-0.70.5
Distance traveled before self-admin0.10.10.30.3-0.3-0.30.3-0.3-0.3-0.30.3-0.20.30.3-0.2-0.4-0.30.40.4-0.10.1-0.20.30.5-0.0
Distance traveled after self-admin0.40.40.7-0.60.70.6-0.70.80.70.7-0.70.8-0.7-0.60.80.60.7-0.7-0.60.6-0.60.6-0.9-0.40.5
Extensor digitorum longus weight4.819.120.84.4-4.3-4.44.4-4.3-4.4-4.44.4-4.34.44.3-4.4-4.2-4.34.34.3-4.54.5-4.54.34.2-4.6
Bone: elastic displacement1.01.11.31.1-1.0-1.11.1-1.1-1.1-1.11.1-1.11.11.1-1.0-1.0-1.01.01.0-1.11.1-1.11.01.0-1.1
Bone: elastic work1.31.72.11.3-1.3-1.31.3-1.3-1.3-1.31.3-1.31.31.3-1.3-1.3-1.31.31.2-1.41.4-1.31.21.2-1.3
Bone: endosteal estimation0.30.60.80.7-0.9-0.70.8-0.8-0.8-0.80.8-0.80.80.8-0.9-0.9-0.80.80.8-0.80.8-0.50.80.9-0.3
Bone: endosteal perimeter0.10.20.40.4-0.6-0.40.5-0.5-0.5-0.50.5-0.50.50.5-0.6-0.6-0.50.50.4-0.50.5-0.30.40.5-0.1
Epididymis fat weight15.135.137.2-6.05.96.0-6.05.86.06.0-6.05.8-5.9-5.85.95.95.8-5.9-6.05.9-5.96.1-5.9-5.96.1
Delta time in closed arm before/after self-admin0.00.00.1-0.20.10.2-0.20.20.20.2-0.20.2-0.2-0.2-0.00.10.2-0.2-0.20.2-0.20.2-0.2-0.30.2
Delta time in open arm before/after self-admin0.50.51.20.7-0.6-0.70.7-0.7-0.7-0.70.7-0.70.70.6-0.6-0.6-0.60.60.6-0.70.7-0.90.50.4-1.1
Diff in mean of infusions in LGA sessions0.10.10.40.3-0.1-0.30.3-0.4-0.3-0.30.3-0.50.30.6-0.1-0.2-0.50.20.1-0.30.3-0.30.20.3-0.5
Delay discount exponential model param1.81.92.5-1.41.41.4-1.41.41.41.4-1.41.5-1.4-1.01.41.41.1-1.4-1.61.4-1.41.4-1.5-1.51.4
Extinction: sum of active levers before priming0.90.91.11.0-0.9-1.01.0-1.0-0.9-0.90.9-1.00.90.9-1.0-0.9-1.00.90.9-1.01.0-1.01.10.9-0.9
Active lever presses in extinction session 60.00.00.10.1-0.2-0.00.1-0.1-0.1-0.00.0-0.20.00.3-0.1-0.2-0.30.0-0.20.2-0.2-0.0-0.2-0.1-0.0
Bone: final force0.10.20.40.4-0.4-0.40.4-0.4-0.4-0.40.4-0.40.40.4-0.4-0.4-0.30.40.4-0.60.6-0.50.30.3-0.4
Bone: final moment0.10.20.40.4-0.5-0.40.4-0.5-0.4-0.40.4-0.40.40.4-0.5-0.4-0.40.40.4-0.60.6-0.50.30.4-0.4
Food consumed during 24 hour testing period0.20.30.50.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.40.5-0.70.7-0.60.40.5-0.5
Glucose0.50.71.4-0.90.70.9-0.80.70.80.8-0.80.7-0.8-0.70.60.70.7-0.8-0.91.2-1.21.1-1.0-0.71.0
Heart weight10.114.315.5-3.83.93.8-3.83.93.83.8-3.83.9-3.8-3.93.83.83.9-3.8-3.73.5-3.53.6-3.7-3.83.8
Delay discount hyperbolic model param1.61.62.1-1.31.31.3-1.31.31.31.3-1.31.3-1.3-0.91.31.31.0-1.3-1.51.3-1.31.3-1.4-1.41.3
Intermittent access intake day 1-15 change0.00.00.2-0.10.10.0-0.10.20.00.0-0.00.2-0.0-0.20.20.00.20.00.1-0.10.10.10.50.20.2
Intermittent access intake escalation0.10.10.3-0.30.30.3-0.30.50.30.3-0.30.5-0.3-0.40.50.30.4-0.3-0.20.1-0.10.30.2-0.10.5
Intermittent access intake escalation 20.70.71.0-0.80.80.8-0.91.00.80.8-0.81.0-0.8-0.91.00.70.9-0.8-0.70.5-0.50.8-0.3-0.61.0
Intermitt. access day 1 inactive lever presses0.00.00.1-0.1-0.00.1-0.10.00.10.1-0.1-0.0-0.1-0.10.0-0.00.1-0.1-0.10.2-0.20.0-0.3-0.10.1
Intermitt. access day 15 inactive lever presses4.04.45.42.1-2.1-2.12.1-2.0-2.1-2.12.1-2.02.02.1-2.1-2.1-2.12.02.0-2.32.3-2.22.01.8-2.1
Intermitt. access escalation Index0.70.61.5-0.80.80.8-0.80.60.80.8-0.80.6-0.8-0.60.60.80.6-0.9-1.00.9-0.90.5-0.9-1.20.3
Intermittent access day 1 total infusions4.04.75.52.2-2.3-2.22.2-2.1-2.2-2.22.1-2.12.12.3-2.2-2.2-2.32.12.0-2.22.2-2.32.01.9-2.3
Intermittent access day 15 total infusions1.31.52.21.2-1.2-1.21.2-1.0-1.2-1.21.2-1.01.21.2-1.2-1.2-1.21.21.3-1.41.4-1.31.51.2-1.2
Intermittent access terminal intake (last 3 days)1.11.21.91.1-1.1-1.11.1-0.8-1.1-1.11.1-0.81.01.0-1.0-1.1-1.01.11.2-1.21.2-1.21.41.1-1.2
Intermittent access total infusions1.51.62.11.3-1.3-1.31.3-1.1-1.3-1.31.3-1.11.31.3-1.2-1.3-1.31.31.3-1.31.3-1.31.41.2-1.2
Intermittent access day 1 locomotion2.32.43.21.6-1.6-1.61.6-1.5-1.5-1.51.5-1.51.51.6-1.6-1.6-1.61.51.5-1.71.7-1.81.31.3-1.6
Intermittent access day 15 total locomotion0.40.40.60.6-0.7-0.60.6-0.5-0.6-0.60.6-0.50.60.6-0.6-0.7-0.60.60.7-0.80.8-0.70.60.7-0.6
Intermittent access total locomotion0.10.20.40.4-0.5-0.40.4-0.3-0.4-0.40.4-0.40.40.4-0.3-0.5-0.40.40.4-0.60.6-0.50.40.3-0.3
Intermittent access standard deviation0.00.00.1-0.0-0.10.0-0.0-0.10.00.0-0.0-0.1-0.0-0.10.1-0.20.1-0.0-0.0-0.30.30.00.2-0.10.1
Left kidney weight0.00.10.50.2-0.1-0.30.20.0-0.2-0.30.20.00.30.1-0.0-0.0-0.10.30.4-0.40.4-0.10.70.6-0.2
Right kidney weight0.51.31.7-1.21.11.2-1.21.31.21.1-1.11.3-1.1-1.31.21.21.2-1.1-1.01.0-1.01.3-0.8-0.91.3
Cocaine induced anxiety0.00.00.10.2-0.2-0.20.2-0.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.20.20.20.0-0.0-0.20.40.1-0.3
Post-drug Anxiety0.70.81.3-0.90.80.9-0.90.90.90.9-0.90.9-0.9-0.90.90.80.9-0.8-0.91.1-1.11.0-0.8-0.80.9
Baseline Anxiety0.50.50.8-0.70.60.7-0.70.70.70.7-0.70.7-0.7-0.70.70.60.7-0.7-0.70.8-0.80.9-0.7-0.50.9
Tail length0.20.61.1-0.80.90.8-0.80.80.80.8-0.70.8-0.7-0.70.80.80.7-0.7-0.81.0-1.00.8-0.6-0.71.0
Length with tail1.45.17.1-2.32.12.3-2.32.22.32.3-2.32.2-2.3-2.32.22.22.2-2.2-2.22.4-2.42.4-2.2-2.02.7
Length without tail0.61.42.6-1.20.91.3-1.21.01.21.2-1.21.0-1.2-1.10.90.91.1-1.2-1.21.2-1.21.5-1.5-1.01.6
Times rat made contact with spout2.63.03.31.7-1.8-1.71.8-1.8-1.8-1.71.7-1.81.71.8-1.8-1.8-1.81.71.7-1.71.7-1.71.71.7-1.7
Lifetime Intake1.82.02.51.4-1.6-1.41.4-1.3-1.4-1.41.4-1.31.41.5-1.5-1.5-1.51.41.3-1.51.5-1.41.41.3-1.4
Liver weight, left1.72.74.4-1.71.41.7-1.61.51.61.6-1.61.5-1.6-1.51.41.51.5-1.5-1.61.9-1.92.1-1.6-1.52.0
Liver weight, right9.615.917.6-4.03.94.0-4.04.04.04.0-4.04.0-4.0-4.03.93.93.9-4.0-3.94.1-4.14.0-3.9-3.94.2
Locomotor activity0.00.00.10.1-0.1-0.10.00.0-0.1-0.10.10.0-0.0-0.1-0.1-0.10.20.00.1-0.20.2-0.4-0.20.2-0.3
Locomotor testing distance0.50.91.41.0-0.8-1.00.9-0.9-0.9-0.90.9-0.80.90.7-0.8-0.9-0.70.91.0-1.21.2-1.20.81.0-1.1
Locomotor testing rearing0.60.91.21.0-0.9-0.90.9-1.1-0.9-0.90.9-1.10.91.1-0.9-0.9-1.00.90.8-0.90.9-1.10.60.9-1.1
Locomotion in novel chamber1.11.42.0-1.21.01.2-1.21.11.21.2-1.21.1-1.2-1.11.00.91.0-1.2-1.31.3-1.31.3-1.4-1.31.3
Locomotion in novel chamber post-restriction1.82.12.5-1.51.51.5-1.41.41.51.5-1.51.4-1.4-1.41.51.51.3-1.4-1.51.6-1.61.5-1.5-1.41.4
Fecal boli incidents, locomotor time 10.60.60.80.8-0.9-0.80.8-0.8-0.8-0.80.8-0.80.80.8-0.9-0.9-0.60.90.9-0.70.7-0.60.90.9-0.6
Change in fecal boli incidents, locomotor task4.34.14.6-2.02.02.0-2.02.02.02.0-2.02.0-2.0-2.12.02.11.9-2.1-2.12.1-2.11.8-2.1-2.11.8
Time >=10cm from walls, locomotor time 10.10.10.20.3-0.5-0.30.3-0.3-0.3-0.30.3-0.30.30.1-0.5-0.3-0.10.30.4-0.30.3-0.10.40.3-0.2
Bouts of movement, locomotor time 14.24.65.82.2-2.1-2.22.1-2.1-2.2-2.22.2-2.02.11.7-2.0-2.1-1.82.22.4-2.22.2-2.02.32.4-2.0
Total resting periods, locomotor time 14.14.55.72.2-2.1-2.22.1-2.1-2.1-2.22.2-2.02.11.8-2.0-2.1-1.82.22.4-2.32.3-1.92.32.4-2.0
Rest time, locomotor task time 10.00.00.10.1-0.2-0.10.1-0.1-0.1-0.10.1-0.10.10.2-0.2-0.2-0.10.20.2-0.20.20.20.20.20.2
Distance moved, locomotor task time 10.91.01.3-1.01.11.0-1.01.11.01.0-1.00.9-1.0-1.00.91.11.0-1.1-1.01.0-1.00.6-1.1-1.10.6
Vertical activity count, locomotor time 10.30.30.4-0.60.60.5-0.60.60.60.5-0.60.5-0.5-0.50.60.60.5-0.6-0.60.5-0.50.4-0.5-0.50.5
Time >=10cm from walls, locomotor time 20.00.00.10.1-0.3-0.00.1-0.1-0.1-0.10.1-0.00.0-0.1-0.3-0.20.00.10.10.1-0.10.10.00.00.1
Bouts of movement, locomotor time 20.00.00.3-0.2-0.10.2-0.10.20.10.1-0.10.2-0.1-0.3-0.00.10.2-0.10.00.0-0.00.5-0.00.00.4
Total resting periods, locomotor time 20.00.00.1-0.0-0.2-0.00.00.0-0.1-0.10.10.00.1-0.1-0.2-0.10.00.10.2-0.10.10.40.20.20.3
Rest time, locomotor task time 21.71.92.41.3-1.4-1.41.4-1.4-1.4-1.41.4-1.51.41.3-1.4-1.4-1.31.51.5-1.41.4-1.11.51.5-1.1
Distance moved, locomotor task time 21.21.41.6-1.21.21.2-1.21.31.21.2-1.21.2-1.2-1.21.21.31.2-1.3-1.21.2-1.20.9-1.3-1.30.9
Vertical activity count, locomotor time 21.01.11.3-1.01.01.0-1.01.11.01.0-1.01.1-1.0-1.01.01.11.0-1.0-1.01.0-1.01.2-1.0-1.01.1
Light reinforcement 14.27.69.02.8-2.9-2.82.8-2.8-2.8-2.82.8-2.82.72.8-2.9-2.9-2.72.72.7-2.72.7-3.02.42.6-3.0
Light reinforcement 23.44.65.52.1-2.3-2.12.1-2.2-2.1-2.12.1-2.12.12.2-2.3-2.2-2.22.12.1-2.12.1-2.02.02.0-2.0
Bone: marrow area0.30.70.90.8-0.9-0.80.8-0.9-0.8-0.80.8-0.90.90.9-0.9-0.9-0.90.90.9-0.80.8-0.60.91.0-0.4
Bone: maximum diameter1.01.82.21.3-1.4-1.31.3-1.3-1.3-1.31.3-1.31.31.3-1.4-1.3-1.31.31.4-1.51.5-1.31.41.4-1.2
Bone: maximum force0.00.00.10.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.10.1-0.2-0.1-0.00.10.1-0.30.3-0.20.00.0-0.1
Bone: maximum moment0.00.00.10.2-0.3-0.20.2-0.2-0.2-0.20.2-0.20.20.2-0.3-0.2-0.10.20.2-0.40.4-0.20.10.1-0.2
Mean time between licks in bursts2.33.23.9-1.81.81.8-1.81.71.81.8-1.81.7-1.8-1.81.81.81.8-1.8-1.81.8-1.82.0-1.7-1.71.9
Mean num. licks in bursts0.10.10.20.3-0.3-0.30.3-0.3-0.3-0.30.3-0.30.30.3-0.3-0.3-0.30.30.4-0.40.4-0.40.30.3-0.4
Cd content in liver0.00.00.10.2-0.2-0.20.2-0.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.00.20.2-0.30.3-0.30.20.2-0.3
Co content in liver7.08.19.82.9-2.7-2.92.8-2.7-2.8-2.92.9-2.72.82.7-2.7-2.7-2.62.82.9-3.03.0-3.12.92.8-3.1
Cu content in liver0.10.10.20.3-0.2-0.30.3-0.2-0.3-0.30.3-0.20.30.2-0.2-0.2-0.20.30.3-0.30.3-0.40.30.2-0.5
Fe content in liver0.10.10.1-0.30.30.3-0.30.30.30.3-0.30.3-0.3-0.30.20.30.3-0.3-0.30.2-0.20.3-0.3-0.30.4
K content in liver0.20.20.6-0.50.30.4-0.40.30.40.4-0.40.3-0.4-0.30.30.30.2-0.3-0.40.6-0.60.7-0.3-0.30.8
Mg content in liver0.30.30.5-0.50.50.5-0.50.50.50.5-0.50.5-0.5-0.50.50.50.4-0.5-0.50.7-0.70.6-0.4-0.50.7
Mn content in liver0.30.40.50.6-0.6-0.60.6-0.7-0.6-0.60.6-0.70.60.7-0.6-0.6-0.70.60.6-0.50.5-0.50.60.6-0.5
Na content in liver0.20.20.30.4-0.5-0.40.5-0.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.50.4-0.50.5-0.30.40.5-0.2
Rb content in liver0.00.00.0-0.10.10.1-0.10.10.10.1-0.10.1-0.1-0.10.10.10.1-0.1-0.00.2-0.20.10.0-0.10.1
Se content in liver0.60.70.8-0.90.90.9-0.90.90.90.9-0.90.9-0.9-0.90.90.90.9-0.9-0.90.8-0.80.8-0.9-0.90.7
Sr content in liver0.00.00.2-0.20.10.2-0.10.10.10.2-0.10.1-0.1-0.10.10.10.1-0.1-0.20.4-0.40.4-0.1-0.10.4
Zn content in liver1.01.11.6-0.91.20.9-1.11.21.11.0-1.01.2-1.1-1.21.21.21.2-1.2-1.00.7-0.70.3-1.1-1.20.2
Bone: minimum diameter0.10.20.3-0.40.40.4-0.40.50.40.4-0.40.5-0.5-0.50.40.40.5-0.5-0.40.2-0.20.3-0.4-0.40.5
Time in familiar zone, hab. session 10.90.81.0-0.90.90.9-0.91.00.90.9-0.90.9-0.9-0.90.90.91.0-0.9-0.90.9-0.90.7-1.0-0.90.7
Time in novel zone, hab. session 10.70.70.8-0.80.90.8-0.80.80.80.8-0.80.8-0.8-0.80.90.90.8-0.8-0.80.8-0.80.9-0.7-0.80.7
Total zone transitions, hab. session 10.10.10.20.4-0.3-0.40.4-0.3-0.4-0.40.4-0.40.40.4-0.3-0.3-0.40.40.4-0.40.4-0.40.40.4-0.4
Total locomotion distance, hab. session 10.10.10.10.3-0.3-0.30.3-0.2-0.3-0.30.3-0.30.30.3-0.3-0.3-0.30.30.3-0.30.3-0.30.20.3-0.3
Locomotion velocity, hab. session 10.91.31.51.2-1.1-1.21.2-1.1-1.2-1.21.2-1.11.21.1-1.1-1.1-1.21.21.1-1.21.2-1.11.11.2-1.1
Time in familiar zone, hab. session 20.00.00.1-0.10.20.0-0.10.10.10.1-0.10.1-0.1-0.10.20.20.1-0.1-0.1-0.10.1-0.1-0.0-0.1-0.1
Time in novel zone, hab. session 20.30.30.6-0.60.40.6-0.60.50.60.6-0.60.5-0.6-0.50.40.40.6-0.5-0.60.8-0.80.7-0.6-0.50.7
Total zone transitions, hab. session 20.20.20.30.5-0.4-0.50.5-0.5-0.5-0.50.5-0.50.50.5-0.4-0.4-0.50.50.5-0.50.5-0.60.50.4-0.4
Total locomotion distance, hab. session 20.20.30.30.5-0.5-0.50.5-0.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.60.60.5-0.50.5-0.50.50.5-0.4
Locomotion velocity, hab. session 20.50.60.70.8-0.8-0.80.8-0.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.80.80.8-0.70.7-0.80.80.8-0.7
Novel to familiar place preference ratio0.50.50.7-0.70.60.7-0.70.80.70.7-0.70.8-0.7-0.80.70.60.8-0.7-0.70.5-0.50.6-0.7-0.80.6
Novelty place preference0.90.91.2-1.00.91.0-1.01.01.01.0-1.01.0-1.0-1.00.90.91.1-1.0-0.90.8-0.80.9-0.9-1.10.9
Time in novel zone, NPP test1.21.31.5-1.11.01.1-1.21.21.21.2-1.21.2-1.2-1.21.11.01.2-1.2-1.11.0-1.01.1-1.1-1.21.0
Total zone transitions, NPP test1.52.12.61.5-1.4-1.51.5-1.5-1.5-1.51.5-1.51.51.5-1.4-1.4-1.51.51.5-1.41.4-1.61.51.4-1.3
Total locomotion distance, NPP test1.82.52.81.6-1.5-1.61.6-1.6-1.6-1.61.6-1.61.61.6-1.5-1.5-1.61.61.6-1.51.5-1.61.71.6-1.4
Locomotion velocity, NPP test3.44.85.32.2-2.1-2.22.2-2.2-2.2-2.22.2-2.22.22.2-2.1-2.1-2.22.22.2-2.22.2-2.22.32.2-2.1
Intraocular pressure3.44.85.5-2.22.32.2-2.22.22.22.2-2.22.2-2.2-2.22.32.32.2-2.2-2.22.1-2.12.0-2.1-2.12.2
Delta distance traveled before/after self-admin1.82.02.7-1.41.41.4-1.41.41.41.4-1.41.4-1.5-1.31.41.31.4-1.5-1.51.3-1.31.3-1.6-1.41.1
Delta ambulatory time before/after self-admin0.40.40.8-0.60.60.7-0.70.70.70.7-0.70.6-0.7-0.50.70.50.7-0.7-0.70.6-0.60.5-0.9-0.70.5
Parametrial fat weight5.610.912.8-3.33.33.3-3.33.13.33.4-3.43.2-3.4-3.43.33.33.3-3.4-3.43.2-3.23.1-3.6-3.43.0
Pavlov. Cond. lever latency1.72.22.6-1.41.51.4-1.51.51.51.5-1.51.5-1.5-1.51.51.51.4-1.5-1.51.6-1.61.3-1.4-1.51.2
Pavlov. Cond. magazine entry latency0.00.00.00.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.10.1-0.1-0.1-0.10.10.1-0.20.2-0.10.10.20.0
Pavlov. Cond. change in total contacts0.10.10.10.2-0.2-0.20.2-0.3-0.2-0.20.2-0.30.20.3-0.3-0.2-0.20.20.2-0.40.4-0.10.20.30.1
Pavlov. Cond. index score0.70.91.20.9-0.9-0.90.9-1.0-0.9-0.90.9-1.01.01.0-1.0-0.9-0.91.00.9-1.11.1-0.80.91.0-0.7
Pavlov. Cond. latency score0.60.81.10.9-0.9-0.90.9-0.9-0.9-0.90.9-0.90.90.9-1.0-0.9-0.90.90.9-1.01.0-0.70.91.0-0.6
Pavlov. Cond. lever contacts1.21.41.71.1-1.2-1.11.2-1.2-1.2-1.21.2-1.21.21.2-1.3-1.2-1.21.21.2-1.31.3-1.01.11.3-1.0
Pavlov. Cond. magazine entry number0.30.40.5-0.60.60.6-0.60.70.70.6-0.60.6-0.7-0.60.70.60.7-0.7-0.70.7-0.70.5-0.7-0.70.4
Pavlov. Cond. intertrial magazine entries1.51.82.11.4-1.4-1.31.3-1.4-1.3-1.31.3-1.41.31.4-1.4-1.4-1.41.31.3-1.21.2-1.31.21.3-1.4
Pavlov. Cond. lever-magazine prob. diff.1.72.12.71.4-1.4-1.41.4-1.5-1.5-1.41.4-1.51.51.5-1.5-1.4-1.41.51.4-1.61.6-1.31.41.5-1.2
Pavlov. Cond. response bias1.41.72.01.3-1.3-1.31.3-1.3-1.3-1.31.3-1.31.31.3-1.4-1.3-1.31.31.3-1.41.4-1.11.31.4-1.1
Pavlov. Cond. lever latency1.72.32.5-1.51.51.5-1.51.61.51.5-1.51.6-1.5-1.61.51.61.6-1.5-1.51.4-1.41.4-1.5-1.61.4
Pavlov. Cond. magazine entry latency0.10.10.20.4-0.3-0.40.4-0.3-0.4-0.40.4-0.30.40.3-0.3-0.3-0.30.40.4-0.30.3-0.40.40.4-0.5
Pavlov. Cond. change in total contacts0.60.91.00.9-1.0-0.90.9-1.0-1.0-0.91.0-1.01.01.0-1.0-1.0-1.01.00.9-0.90.9-0.71.01.0-0.6
Pavlov. Cond. index score0.81.01.21.0-1.1-1.01.0-1.1-1.0-1.01.0-1.11.01.1-1.0-1.1-1.11.11.0-0.90.9-0.81.01.1-0.8
Pavlov. Cond. latency score0.70.91.10.9-1.0-0.91.0-1.0-1.0-1.01.0-1.01.01.0-1.0-1.0-1.01.01.0-0.80.8-0.81.01.0-0.8
Pavlov. Cond. lever contacts0.91.21.51.1-1.1-1.11.1-1.2-1.1-1.11.1-1.21.11.2-1.1-1.2-1.21.11.1-1.01.0-0.91.11.2-0.9
Pavlov. Cond. magazine entry number0.00.10.1-0.20.20.2-0.20.20.20.2-0.20.2-0.2-0.20.20.20.2-0.2-0.30.3-0.30.2-0.3-0.30.3
Pavlov. Cond. intertrial magazine entries2.73.53.9-1.92.01.9-1.91.91.91.9-1.91.9-1.9-1.92.01.91.9-1.9-1.91.8-1.81.8-1.7-1.91.7
Pavlov. Cond. lever-magazine prob. diff.0.50.70.80.8-0.9-0.80.8-0.9-0.8-0.80.8-0.90.80.9-0.9-0.9-0.90.90.8-0.70.7-0.60.90.9-0.6
Pavlov. Cond. response bias1.72.32.51.5-1.6-1.51.5-1.6-1.5-1.51.5-1.61.51.6-1.5-1.6-1.61.61.5-1.51.5-1.41.51.6-1.3
Time in closed arm before self-admin0.60.71.2-0.81.10.8-0.81.00.80.8-0.80.9-0.8-0.71.00.90.8-0.8-0.90.6-0.60.7-0.6-0.80.7
Time in closed arm after self-admin1.51.62.0-1.31.41.3-1.31.31.31.3-1.31.2-1.3-1.11.31.21.2-1.3-1.31.2-1.21.3-1.1-1.11.2
Time in open arm before self-admin0.20.20.40.4-0.6-0.40.5-0.5-0.5-0.50.5-0.40.50.4-0.5-0.5-0.60.50.5-0.20.2-0.30.40.5-0.3
Time in open arm after self-admin2.73.03.81.8-1.9-1.71.7-1.8-1.8-1.71.7-1.81.71.6-1.8-1.8-1.71.71.7-1.51.5-1.81.51.4-1.9
Bone: periosteal estimation0.61.21.51.1-1.1-1.11.1-1.1-1.1-1.11.1-1.11.11.1-1.2-1.1-1.01.11.1-1.21.2-1.01.11.1-0.7
Bone: periosteal perimeter0.20.40.50.6-0.7-0.60.6-0.6-0.6-0.60.6-0.60.60.6-0.7-0.7-0.60.60.6-0.70.7-0.50.50.6-0.3
Bone: post-yield work0.40.50.60.7-0.8-0.70.7-0.7-0.7-0.70.7-0.70.70.7-0.8-0.7-0.70.70.7-0.80.8-0.60.70.7-0.8
Progressive ratio test 1 active lever presses0.30.30.50.6-0.7-0.60.6-0.6-0.6-0.60.6-0.60.60.7-0.7-0.7-0.70.60.5-0.50.5-0.50.40.7-0.5
Progressive ratio test 1 breakpoint0.30.30.50.6-0.7-0.50.6-0.5-0.5-0.50.5-0.50.50.7-0.6-0.6-0.70.50.5-0.40.4-0.50.40.6-0.4
Progressive ratio test 1 inactive lever presses0.91.01.41.0-1.2-1.01.0-1.0-1.0-1.01.0-1.11.01.1-1.1-1.1-1.10.90.8-1.11.1-1.10.80.7-1.0
Progressive ratio test 2 active lever presses0.00.00.2-0.10.10.1-0.10.40.20.1-0.10.4-0.1-0.20.20.20.2-0.10.00.3-0.30.30.10.10.2
Progressive ratio test 2 breakpoint0.00.00.1-0.10.10.1-0.10.30.10.1-0.10.3-0.1-0.10.20.10.1-0.00.10.2-0.20.20.20.20.1
Progressive ratio test 2 inactive lever presses0.50.60.80.8-0.9-0.80.8-0.6-0.8-0.80.8-0.70.70.8-0.8-0.9-0.80.70.8-0.90.9-0.70.80.6-0.9
Incentive Sensitization - Responses0.10.10.4-0.30.40.3-0.30.60.30.3-0.30.6-0.3-0.50.50.40.5-0.3-0.10.4-0.40.40.1-0.10.2
Incentive Sensitization - Breakpoint0.30.30.7-0.50.60.5-0.60.80.60.5-0.50.8-0.5-0.70.80.60.7-0.5-0.30.6-0.60.6-0.1-0.30.4
Sum of active levers in priming session hrs 5-61.31.21.41.1-1.1-1.11.1-1.0-1.1-1.11.1-1.01.11.2-1.0-1.2-1.11.11.1-1.11.1-1.11.21.2-1.1
Progressive ratio0.50.61.0-0.80.60.8-0.70.80.70.8-0.80.8-0.7-0.50.60.60.5-0.8-0.90.8-0.81.0-0.9-0.81.0
Food seeking constrained by brief footshock2.43.03.41.7-1.7-1.71.7-1.7-1.7-1.71.7-1.61.71.6-1.7-1.7-1.61.71.8-1.81.8-1.81.81.8-1.8
Seeking ratio, punishment vs. effort1.72.12.61.5-1.3-1.51.4-1.5-1.4-1.41.4-1.51.41.2-1.3-1.3-1.21.41.5-1.61.6-1.61.61.4-1.6
Retroperitoneal fat weight21.971.974.1-8.68.48.6-8.58.58.58.5-8.58.5-8.5-8.58.38.48.5-8.5-8.58.4-8.48.4-8.6-8.58.4
Reaction time number correct0.60.91.51.0-0.8-1.01.0-1.0-1.0-1.01.0-1.01.01.0-0.8-0.8-0.91.01.0-1.01.0-0.81.21.0-0.7
Reaction time mean minus median0.00.00.20.1-0.0-0.10.00.2-0.0-0.10.00.20.0-0.10.10.20.1-0.00.2-0.40.4-0.50.00.1-0.4
Reaction time mean minus median AUC0.00.00.1-0.00.10.0-0.10.30.10.1-0.10.3-0.2-0.30.20.30.2-0.10.0-0.20.2-0.3-0.2-0.1-0.1
Reaction time num false alarms0.30.40.60.7-0.7-0.70.7-0.7-0.7-0.70.7-0.60.70.6-0.7-0.8-0.70.70.7-0.60.6-0.60.70.6-0.6
Reaction time num false alarms AUC0.60.81.00.9-0.9-0.90.9-0.9-0.9-0.90.9-0.70.90.8-0.9-1.0-0.80.91.0-0.90.9-0.91.00.8-0.9
Reaction time trials correct on left0.60.91.51.0-0.8-1.01.0-1.0-1.0-1.01.0-1.01.01.0-0.8-0.8-0.91.01.0-1.01.0-0.81.21.0-0.7
Reaction time trials on left0.71.01.51.0-0.8-1.01.0-1.1-1.0-1.01.0-1.01.11.0-0.9-0.9-1.01.11.1-1.01.0-0.91.21.1-0.8
Reaction time mean1.01.42.0-1.21.31.1-1.21.41.21.2-1.21.3-1.2-1.31.31.41.2-1.2-1.21.0-1.00.9-1.2-1.30.7
Reaction time mean AUC0.81.11.7-1.01.21.0-1.11.31.11.1-1.11.2-1.1-1.11.21.31.1-1.1-1.00.8-0.80.7-1.1-1.10.6
Median of all reaction times1.11.52.0-1.21.31.2-1.21.41.31.2-1.21.3-1.2-1.31.31.41.2-1.3-1.21.1-1.11.0-1.2-1.30.8
Reaction time omissions0.10.10.40.3-0.2-0.30.3-0.3-0.3-0.30.3-0.30.30.4-0.2-0.2-0.40.30.3-0.20.2-0.50.10.2-0.6
Reaction time false alarm rate0.00.10.20.2-0.3-0.20.2-0.2-0.2-0.20.2-0.10.20.2-0.3-0.4-0.20.20.2-0.20.2-0.30.20.1-0.3
Reaction time premature initiation rate0.10.10.2-0.40.20.4-0.40.40.40.4-0.40.3-0.4-0.40.20.30.4-0.3-0.30.5-0.50.5-0.5-0.40.5
Reaction time premature initiations0.00.00.10.2-0.3-0.20.2-0.2-0.2-0.20.2-0.20.20.2-0.3-0.2-0.10.30.3-0.10.1-0.00.30.3-0.0
Std. dev. reaction times0.40.50.8-0.70.80.6-0.70.90.70.7-0.70.8-0.7-0.70.90.90.7-0.7-0.60.5-0.50.4-0.7-0.70.4
Reaction time trials completed0.71.01.51.0-0.8-1.01.0-1.1-1.0-1.01.0-1.01.11.0-0.9-0.9-1.01.11.1-1.01.0-0.91.21.1-0.8
Reaction time trials AUC0.91.32.01.1-1.0-1.21.1-1.2-1.1-1.21.2-1.11.21.1-1.0-1.0-1.11.21.2-1.11.1-1.01.41.2-0.9
Run reversals in cocaine runway, females0.00.00.10.1-0.2-0.10.1-0.0-0.1-0.10.1-0.00.10.2-0.2-0.2-0.10.20.2-0.00.00.10.30.30.1
Run reversals in cocaine runway, males0.60.61.00.8-0.6-0.80.8-0.7-0.7-0.80.8-0.60.80.7-0.7-0.6-0.70.70.8-1.01.0-0.91.00.7-0.6
Latency to leave start box in cocaine runway0.30.30.80.6-0.5-0.60.6-0.6-0.6-0.60.6-0.60.60.7-0.5-0.5-0.70.60.5-0.40.4-0.70.40.5-0.9
Latency to leave start box in cocaine runway, F0.50.50.80.7-0.7-0.70.7-0.9-0.7-0.70.7-0.90.70.9-0.7-0.7-0.90.70.6-0.40.4-0.80.60.6-0.9
Latency to leave start box in cocaine runway, M0.10.10.20.3-0.3-0.30.3-0.3-0.3-0.30.3-0.30.30.4-0.4-0.3-0.50.30.3-0.20.2-0.20.10.4-0.3
Std. dev. time between licks in bursts0.10.10.1-0.30.30.3-0.30.30.30.3-0.30.3-0.3-0.30.20.30.3-0.3-0.30.1-0.10.2-0.3-0.30.1
Total sessions with >9 infusions0.70.81.10.9-1.0-0.80.9-0.9-0.9-0.80.8-0.90.81.0-1.1-0.9-1.00.80.7-0.90.9-1.00.40.6-0.9
Short access day 1 total inactive lever presses2.93.24.31.8-1.9-1.81.8-2.0-1.8-1.81.8-2.01.82.0-2.0-1.8-2.01.71.5-1.71.7-1.91.51.3-2.1
Short access day 10 total inactive lever presses0.50.50.80.7-0.8-0.70.7-0.9-0.7-0.70.7-0.90.70.8-0.9-0.8-0.80.70.6-0.70.7-0.80.50.5-0.5
Short access day 1 total infusions1.71.82.91.3-1.5-1.31.3-1.6-1.3-1.31.3-1.51.31.7-1.6-1.4-1.71.20.9-1.31.3-1.50.70.7-1.5
Short access day 10 total infusions3.03.33.71.8-1.9-1.81.8-1.8-1.8-1.81.8-1.81.81.9-1.8-1.9-1.91.81.8-1.71.7-1.71.81.8-1.9
Short access total infusions1.21.31.91.1-1.4-1.11.1-1.2-1.1-1.11.1-1.21.11.3-1.3-1.3-1.31.10.9-1.21.2-1.10.80.9-1.2
Short access day 1 locomotion4.04.35.32.1-2.1-2.12.1-2.0-2.1-2.12.1-2.02.12.1-2.1-2.0-2.12.02.0-2.22.2-2.31.91.9-2.1
Short access day 10 total locomotion0.80.91.71.0-0.9-1.00.9-0.8-0.9-0.90.9-0.80.90.8-0.8-0.8-0.80.91.0-1.31.3-1.21.00.9-1.0
Short access total locomotion0.20.20.50.4-0.5-0.40.4-0.4-0.4-0.40.4-0.40.40.5-0.5-0.5-0.50.40.4-0.70.7-0.70.20.3-0.5
One hour access (0.3 mA shock)1.21.41.81.2-1.3-1.21.2-1.1-1.2-1.21.2-1.11.21.2-1.2-1.3-1.21.21.2-1.01.0-1.11.11.3-1.0
Compulsive drug intake0.10.10.7-0.30.00.3-0.3-0.10.20.3-0.3-0.1-0.3-0.1-0.00.10.1-0.3-0.40.5-0.50.4-0.8-0.30.4
One hour access (shock baseline)1.01.22.01.1-1.1-1.11.1-0.9-1.1-1.11.1-0.91.11.0-0.9-1.1-1.01.11.2-1.11.1-1.11.41.2-1.0
Social response proportion0.50.50.9-0.70.80.7-0.80.90.80.8-0.80.8-0.8-0.90.70.80.9-0.8-0.70.4-0.40.4-1.0-0.70.3
Social responses0.20.20.4-0.30.60.3-0.40.60.40.4-0.40.6-0.5-0.60.60.60.6-0.5-0.4-0.10.1-0.1-0.4-0.3-0.1
Social time1.01.42.4-1.11.31.1-1.21.51.21.2-1.21.5-1.3-1.51.31.41.4-1.3-1.00.5-0.50.6-1.2-1.00.6
Soleus weight5.516.018.14.1-3.9-4.14.0-3.9-4.0-4.04.0-4.04.04.0-3.9-3.9-3.93.94.0-4.14.1-4.34.03.9-4.2
Bone: stiffness0.00.00.1-0.20.10.2-0.20.20.20.2-0.20.2-0.2-0.20.10.20.2-0.2-0.20.0-0.00.3-0.2-0.30.4
Tibialis anterior weight4.113.916.13.8-3.6-3.83.7-3.6-3.7-3.73.7-3.63.73.6-3.7-3.6-3.63.63.7-4.04.0-4.03.63.5-4.0
Time to tail flick, vehicle, before self-admin2.02.12.9-1.41.61.4-1.51.71.51.4-1.41.6-1.5-1.71.51.51.6-1.4-1.31.3-1.31.4-1.0-1.41.1
Time to tail flick, vehicle, after self-admin3.74.05.0-2.02.21.9-2.02.22.02.0-2.02.2-2.0-2.12.22.22.1-2.0-1.91.7-1.71.8-1.7-2.01.6
Time to tail flick, test, before self-admin0.50.50.80.7-0.7-0.70.7-0.7-0.7-0.70.7-0.70.70.9-0.7-0.7-0.70.60.6-0.60.6-0.80.60.6-0.9
Time to tail flick, test, after self-admin0.10.10.2-0.30.20.2-0.30.30.20.2-0.20.2-0.2-0.20.30.20.4-0.2-0.20.4-0.40.4-0.2-0.10.3
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.10.20.1-0.20.20.20.2-0.20.2-0.2-0.00.30.20.2-0.2-0.20.0-0.00.2-0.2-0.00.1
Delta time to tail flick, test, before/after SA0.40.30.60.6-0.6-0.60.6-0.5-0.6-0.60.6-0.60.60.5-0.5-0.6-0.50.60.7-0.50.5-0.30.70.8-0.3
Tibia length2.87.98.2-2.92.82.9-2.92.82.82.9-2.92.8-2.9-2.82.82.82.8-2.9-2.92.7-2.72.8-2.8-2.82.9
Ambulatory time before self-admin0.30.30.60.6-0.6-0.60.6-0.5-0.6-0.60.6-0.50.60.5-0.4-0.7-0.60.60.6-0.40.4-0.40.60.8-0.3
Ambulatory time after self-admin0.30.30.6-0.50.60.5-0.60.70.60.5-0.50.7-0.6-0.60.70.50.6-0.6-0.50.5-0.50.4-0.7-0.40.3
Bone: tissue strength0.50.40.6-0.60.60.7-0.70.60.70.7-0.70.6-0.7-0.60.60.60.7-0.7-0.70.8-0.80.6-0.7-0.70.4
Total heroin consumption2.83.23.81.8-1.8-1.81.9-1.9-1.8-1.81.8-1.81.92.0-1.7-1.7-1.91.81.7-1.71.7-1.81.71.6-1.9
Bone: trabecular number4.26.57.62.6-2.5-2.62.6-2.5-2.6-2.62.6-2.62.52.5-2.5-2.5-2.62.52.5-2.52.5-2.72.42.5-2.7
Bone: trabecular spacing2.32.93.5-1.71.81.7-1.81.81.81.7-1.71.9-1.8-1.81.81.81.9-1.8-1.71.4-1.41.5-1.7-1.71.5
Bone: trabecular thickness0.50.60.70.8-0.8-0.80.8-0.7-0.8-0.80.8-0.70.80.7-0.7-0.8-0.80.80.8-0.70.7-0.80.80.9-0.8
Bone: trabecular tissue density0.10.10.20.3-0.3-0.30.3-0.4-0.3-0.30.3-0.30.40.4-0.3-0.4-0.30.40.4-0.20.20.00.40.4-0.0
Water consumed over 24 hours1.51.82.21.3-1.5-1.31.4-1.4-1.4-1.31.3-1.41.41.4-1.5-1.4-1.41.41.3-1.31.3-1.11.31.3-1.1
Number of responses in last shaping day0.00.00.10.2-0.2-0.20.2-0.1-0.2-0.20.2-0.20.10.1-0.2-0.1-0.10.20.2-0.30.3-0.10.20.2-0.0