Hub : Genes

Pla2g12a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg intron excision ratio chr2_221126136_221126650 0.46 0.17 2.4e-03 -0.01 0.09 0.01 0.02 8.4e-01 1.9e-03 1.6e-01 8.0e-02
2 RMTg intron excision ratio chr2_221126173_221126650 0.47 0.17 1.6e-03 -0.01 0.11 0 0.04 6.4e-01 7.5e-04 3.0e-01 3.2e-02
3 PL gene expression Pla2g12a 0.12 0.08 3.2e-04 0.02 0.04 0.04 0.03 5.9e-03 4.7e-05 6.0e-05 7.5e-04
4 IL gene expression Pla2g12a 0.52 0.3 4.9e-04 0.06 0.11 0.08 0.06 1.4e-02 1.2e-03 5.7e-03 1.6e-02
5 NAcc intron excision ratio chr2_221126173_221126650 0.03 0.03 4.7e-04 0.01 0.02 0.01 0.01 1.9e-03 2.9e-04 5.4e-03 2.3e-03
6 IL mRNA stability Pla2g12a 0.15 0.1 5.6e-04 0.15 0.12 0.14 0.14 2.0e-04 7.6e-04 2.7e-04 2.8e-04
7 NAcc intron excision ratio chr2_221126136_221126650 0.03 0.02 9.8e-04 0.01 0.02 0.01 0.01 5.2e-03 1.0e-03 2.6e-03 7.2e-03
8 Brain intron excision ratio chr2_221126136_221126650 0.02 0.02 4.8e-03 0.02 0.01 0.01 0.01 4.8e-03 1.3e-02 8.0e-02 1.6e-02
9 Brain mRNA stability Pla2g12a 0.22 0.13 5.6e-17 0.16 0.18 0.19 0.17 9.3e-15 9.6e-17 3.9e-17 5.8e-16
10 PL mRNA stability Pla2g12a 0.16 0.07 0.0e+00 0.26 0.25 0.25 0.25 7.4e-28 8.0e-27 2.7e-27 3.3e-27
11 NAcc mRNA stability Pla2g12a 0.11 0.06 0.0e+00 0.15 0.17 0.16 0.16 4.4e-22 7.7e-25 5.9e-23 2.8e-23
12 BLA mRNA stability Pla2g12a 0.15 0.08 2.6e-09 0.11 0.16 0.16 0.15 1.7e-06 1.3e-08 9.6e-09 1.9e-08
13 IC mRNA stability Pla2g12a 0.56 0.22 4.4e-13 0.23 0.23 0.2 0.22 3.9e-10 3.0e-10 1.0e-08 1.3e-09
14 Liver mRNA stability Pla2g12a 0.2 0.1 0.0e+00 0.22 0.23 0.22 0.22 1.9e-23 3.7e-25 2.5e-24 3.1e-24
15 Adipose gene expression Pla2g12a 0.11 0.1 5.1e-03 0.01 0.01 0.01 0.01 1.4e-02 1.3e-02 1.7e-02 1.8e-02
16 pVTA gene expression Pla2g12a 0.14 0.08 6.1e-16 0.15 0.17 0.14 0.16 7.0e-12 1.1e-13 1.3e-11 3.7e-13
17 Liver isoform ratio NM_001395579.1 0.12 0.08 5.2e-12 0.09 0.09 0.07 0.1 2.8e-10 1.8e-10 9.5e-09 1.1e-10
18 Brain gene expression Pla2g12a 0.54 0.17 4.9e-11 0.1 0.12 0.11 0.11 8.3e-10 3.7e-11 1.1e-10 2.8e-10
19 NAcc gene expression Pla2g12a 0.07 0.05 2.2e-11 0.06 0.08 0.08 0.08 4.4e-10 3.7e-12 3.8e-12 4.3e-12
20 OFC gene expression Pla2g12a 0.33 0.23 1.3e-03 0.13 0.1 0.07 0.12 5.2e-04 2.5e-03 9.1e-03 8.2e-04
21 Liver isoform ratio NM_001395580.1 0.12 0.08 1.7e-12 0.1 0.1 0.08 0.1 1.0e-10 7.3e-11 6.1e-09 5.2e-11
22 BLA intron excision ratio chr2_221126136_221126650 0.16 0.11 3.4e-05 0.02 0.06 0.03 0.04 3.1e-02 4.3e-04 6.5e-03 3.8e-03
23 pVTA mRNA stability Pla2g12a 0.31 0.2 0.0e+00 0.2 0.22 0.21 0.23 1.2e-15 9.3e-18 5.3e-17 2.5e-18
24 Adipose isoform ratio NM_001395579.1 0.07 0.05 1.5e-07 0.05 0.06 0.06 0.06 4.5e-06 7.7e-07 7.3e-07 1.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.61.17.6-2.72.8-1.5-1.00.30.3-0.2-0.10.3-0.0-0.2-0.0-0.2-0.2-2.2-0.4-0.3-0.2-0.60.30.30.6-0.5-0.7
Area under the delay curve0.40.42.6-1.61.6-0.8-0.50.50.8-0.4-0.50.90.30.30.20.20.2-0.90.10.40.30.1-0.4-0.30.00.3-0.1
BMI with tail0.82.75.30.4-0.5-1.9-2.31.82.0-1.8-1.61.31.91.71.61.81.81.31.91.50.71.6-1.4-1.6-1.91.72.1
BMI without tail0.72.26.02.3-2.4-0.4-1.31.11.3-1.2-1.10.41.11.31.41.41.42.41.71.20.51.5-1.0-1.2-1.91.52.1
Body weight0.62.85.20.5-0.6-1.6-2.21.81.4-1.9-1.71.21.81.71.91.81.81.51.91.60.91.7-1.4-1.6-2.01.72.3
Weight adjusted by age1.92.84.2-1.61.5-1.8-1.91.91.9-1.9-1.91.92.01.71.81.61.70.41.71.71.31.5-1.6-1.6-1.61.41.5
Bone surface0.20.53.1-1.71.8-1.2-0.80.30.1-0.3-0.10.00.1-0.00.10.0-0.0-1.4-0.1-0.30.1-0.30.30.30.3-0.4-0.2
Bone volume0.50.94.3-2.12.1-1.6-1.30.90.9-0.8-0.70.70.70.50.70.60.6-1.10.40.40.60.3-0.4-0.4-0.20.30.3
Breakpoint value in progressive ratio session0.10.10.4-0.40.40.60.6-0.20.20.20.1-0.2-0.5-0.30.2-0.4-0.3-0.2-0.30.00.3-0.3-0.10.10.4-0.0-0.3
Number of licking bursts0.91.52.8-0.80.7-0.9-1.01.41.6-1.4-1.71.31.21.41.31.21.30.71.31.31.11.3-1.3-1.3-1.31.21.0
Context. condit. distance diff. score0.80.91.3-0.40.3-0.8-0.91.11.0-1.1-1.11.01.01.11.11.01.00.61.01.10.71.0-1.0-1.0-1.01.11.1
Locomotion velocity, session 10.10.10.40.2-0.3-0.4-0.60.40.5-0.4-0.40.10.40.40.30.40.40.30.50.20.00.3-0.1-0.2-0.50.20.5
Locomotion distance, session 10.40.62.1-0.60.5-1.2-1.50.91.1-0.9-1.00.70.70.70.60.60.7-0.00.70.5-0.00.5-0.5-0.4-0.80.60.7
Locomotion velocity, session 21.21.42.10.6-0.6-0.7-0.91.20.4-1.2-1.10.91.41.41.31.41.41.41.41.11.31.4-1.0-1.1-1.51.11.4
Locomotion distance, session 21.31.82.8-0.60.5-1.2-1.51.61.6-1.6-1.71.51.51.51.51.41.50.81.51.31.11.4-1.2-1.2-1.51.31.3
Locomotion velocity, session 33.33.87.8-1.00.8-2.0-2.12.12.8-2.1-2.02.22.12.02.12.02.00.82.02.11.81.9-2.0-2.0-1.92.11.8
Locomotion distance, session 31.31.44.6-1.21.2-2.0-2.11.41.5-1.4-1.31.31.21.00.91.01.1-0.31.10.80.10.8-0.7-0.8-1.00.91.1
Stereotopy head waving bouts, day 30.10.10.4-0.60.6-0.4-0.2-0.00.00.00.30.10.1-0.10.30.0-0.1-0.6-0.10.20.2-0.1-0.3-0.10.20.1-0.2
Stereotopy head waving duration, day 30.10.10.7-0.40.4-0.00.4-0.4-0.30.40.8-0.2-0.1-0.3-0.0-0.1-0.3-0.7-0.4-0.10.5-0.3-0.00.10.6-0.2-0.5
Locomotion velocity, session 72.12.34.8-1.00.9-2.1-2.21.81.0-1.8-1.81.41.81.71.51.71.70.41.61.30.91.5-1.2-1.3-1.61.41.6
Locomotion distance, session 74.15.16.6-0.80.6-2.3-2.62.52.5-2.5-2.52.52.52.52.32.42.51.32.42.31.82.3-2.2-2.3-2.42.42.4
Stereotopy head waving bouts, day 70.10.20.60.4-0.40.50.5-0.2-0.80.20.4-0.6-0.1-0.2-0.0-0.1-0.10.2-0.1-0.60.3-0.00.70.60.1-0.5-0.1
Stereotopy head waving duration, day 70.10.10.40.3-0.30.50.6-0.3-0.50.30.4-0.5-0.2-0.2-0.1-0.1-0.20.1-0.2-0.60.5-0.10.60.60.2-0.5-0.2
Locomotion velocity, session 80.30.41.30.3-0.30.20.00.61.1-0.6-0.90.10.50.80.70.60.71.00.70.20.80.8-0.0-0.1-0.80.20.6
Locomotion distance, session 82.63.85.6-0.40.3-1.3-1.72.22.4-2.2-2.32.02.12.22.22.12.21.52.21.92.02.2-1.9-1.8-2.21.91.9
Degree of sensitization distance0.10.10.40.3-0.40.30.30.2-0.0-0.2-0.30.10.20.40.30.30.30.60.30.40.50.4-0.5-0.4-0.30.30.3
Degree of sensitization stereotypy0.10.10.40.3-0.30.50.5-0.1-0.50.00.2-0.30.00.10.10.10.10.40.1-0.50.70.20.60.4-0.1-0.40.0
Conditioned locomotion0.20.30.50.1-0.1-0.4-0.60.6-0.1-0.6-0.60.40.70.60.50.60.60.50.60.40.40.6-0.3-0.4-0.60.40.5
Cocaine response after cond. corrected4.04.86.3-1.61.5-2.2-2.12.41.8-2.4-2.42.52.52.42.42.42.30.82.22.32.42.2-2.3-2.3-2.12.22.0
Cocaine response after cond. not corrected3.13.75.1-1.21.1-1.8-1.92.21.4-2.2-2.31.92.12.12.22.12.10.92.01.92.12.0-1.9-1.9-1.91.82.0
Cocaine response before conditioning0.50.61.41.2-1.11.10.9-0.8-0.70.70.5-1.2-0.9-0.7-0.6-0.7-0.60.4-0.6-0.9-0.8-0.50.90.90.4-0.7-0.2
Saline control response0.20.21.6-1.21.2-0.6-0.40.20.9-0.1-0.30.20.0-0.1-0.3-0.1-0.1-1.0-0.2-0.0-0.2-0.3-0.00.10.3-0.0-0.3
Bone: connectivity density0.71.15.5-2.32.3-1.9-1.50.90.8-0.9-0.60.90.80.60.60.60.6-1.40.40.40.60.2-0.5-0.4-0.20.30.2
Bone: cortical apparent density0.20.32.0-1.41.4-0.7-0.30.4-0.2-0.4-0.30.70.40.30.40.30.2-0.70.10.40.80.2-0.4-0.40.10.2-0.2
Bone: cortical area1.52.33.70.3-0.21.31.5-1.6-1.81.61.9-1.6-1.4-1.7-1.3-1.6-1.6-1.1-1.6-1.7-0.9-1.61.71.61.7-1.6-1.5
Bone: cortical porosity0.80.82.1-1.11.0-0.8-0.71.11.3-1.0-1.10.90.91.01.10.90.90.10.90.71.50.9-0.7-0.7-0.70.70.7
Bone: cortical porosity1.81.93.9-0.60.5-0.9-1.01.52.0-1.5-1.51.41.51.51.71.51.50.91.51.31.91.5-1.3-1.3-1.41.31.4
Bone: cortical thickness0.61.02.00.9-0.81.41.4-1.2-1.41.11.4-1.0-0.9-1.0-0.7-0.9-1.0-0.1-1.0-1.0-0.1-0.91.11.01.0-0.9-0.8
Bone: cortical thickness0.60.74.92.2-2.21.20.8-0.4-0.80.30.3-0.6-0.1-0.00.30.10.01.60.20.00.40.30.0-0.0-0.30.20.6
Bone: cortical tissue density0.30.32.1-1.51.5-0.7-0.30.4-0.2-0.4-0.30.80.50.30.40.30.3-0.70.10.40.80.2-0.4-0.40.00.2-0.2
Condit. Reinf. active minus inactive responses1.01.12.71.4-1.5-0.3-0.90.80.9-0.9-0.70.31.01.00.91.01.01.61.20.80.51.1-0.8-0.9-1.31.01.5
Condit. Reinf. active-inactive response ratio0.91.02.21.2-1.3-0.3-0.90.81.2-0.8-0.70.40.90.90.91.01.01.51.10.90.61.0-0.8-0.9-1.21.01.4
Condit. Reinf. active responses1.11.42.90.7-0.8-1.2-1.71.21.0-1.3-1.10.71.31.21.01.31.31.21.40.90.31.2-0.9-1.0-1.61.11.7
Condit. Reinf. inactive responses0.20.31.2-0.50.4-1.1-1.10.70.2-0.6-0.60.40.60.50.30.50.5-0.10.50.2-0.20.4-0.3-0.3-0.60.30.5
Incentive salience index mean0.40.53.51.8-1.90.3-0.20.1-0.2-0.20.0-0.40.30.30.30.40.41.50.60.2-0.00.5-0.2-0.2-0.70.41.0
Condit. Reinf. lever presses0.81.13.82.0-1.91.20.8-1.0-1.70.91.0-1.3-0.9-0.8-0.8-0.7-0.70.7-0.6-1.0-1.1-0.61.00.90.4-0.8-0.1
Condit. Reinf. active minus inactive responses0.30.41.00.0-0.1-0.3-0.40.7-0.3-0.7-0.90.51.00.80.70.80.80.80.80.40.80.9-0.5-0.5-0.80.40.7
Condit. Reinf. active-inactive response ratio0.30.41.10.8-0.80.1-0.20.4-0.7-0.4-0.50.20.70.60.50.70.61.10.70.30.60.7-0.4-0.4-0.70.40.7
Condit. Reinf. active responses0.81.12.0-0.40.3-0.6-0.81.20.6-1.2-1.41.11.31.31.21.21.20.91.20.91.41.3-1.0-1.0-1.20.91.0
Condit. Reinf. inactive responses1.72.25.5-2.12.0-1.7-1.61.62.3-1.6-1.71.81.31.41.51.21.3-0.31.21.41.21.1-1.5-1.3-1.01.20.9
Condit. Reinf. lever presses0.20.21.21.1-1.10.90.7-0.3-0.30.2-0.0-0.4-0.10.1-0.1-0.00.00.90.1-0.2-0.00.20.20.2-0.2-0.20.0
Condit. Reinf. lever reinforcers received0.60.81.5-0.30.2-0.4-0.51.00.7-1.0-1.20.91.11.11.01.01.00.81.00.71.21.1-0.8-0.8-1.00.70.8
Conditioned reinforcement - actives1.93.314.7-3.83.8-3.5-2.81.81.3-1.7-1.31.71.61.01.11.11.1-2.30.80.90.70.5-0.8-0.7-0.50.70.6
Conditioned reinforcement - inactives0.91.45.9-2.42.4-2.4-1.91.10.9-1.0-0.80.80.80.60.60.70.6-1.60.50.90.20.2-0.9-0.8-0.20.70.3
Conditioned locomotion4.25.422.4-4.74.7-4.0-3.12.32.1-2.2-1.92.62.21.71.61.81.7-2.31.31.41.61.1-1.4-1.3-0.91.10.7
Patch foraging indifference point 0 sec0.20.42.3-1.51.5-1.0-0.70.1-0.3-0.1-0.20.10.2-0.2-0.4-0.2-0.2-1.3-0.3-0.2-0.4-0.40.30.30.4-0.4-0.5
Patch foraging indifference point AUC0.00.10.2-0.30.30.10.30.0-0.50.0-0.3-0.2-0.1-0.0-0.3-0.1-0.1-0.1-0.1-0.4-0.0-0.00.40.50.0-0.5-0.3
Delay disc. indifference point, 0s delay0.20.20.6-0.20.20.1-0.00.30.4-0.3-0.50.80.00.40.60.30.40.40.30.70.50.4-0.7-0.6-0.30.70.4
Delay disc. indifference point, 16s delay0.91.07.2-2.72.7-1.4-0.90.50.5-0.4-0.41.10.20.10.20.10.1-1.8-0.10.20.2-0.2-0.3-0.10.3-0.0-0.4
Delay disc. indifference point, 2s delay0.20.21.11.0-1.00.70.6-0.2-0.30.10.20.30.00.00.20.10.00.80.10.40.40.2-0.4-0.4-0.10.50.4
Delay disc. indifference point, 24s delay1.31.52.6-0.80.81.21.3-1.2-0.61.20.8-1.0-1.6-1.2-1.0-1.5-1.3-1.2-1.4-1.3-1.3-1.31.11.41.4-1.5-1.5
Delay disc. indifference point, 4s delay1.01.13.9-2.02.0-1.7-1.31.01.2-1.0-0.91.20.90.70.60.70.7-1.00.60.80.60.5-0.8-0.8-0.40.70.4
Delay disc. indifference point, 8s delay0.30.42.3-1.51.5-0.9-0.70.50.9-0.5-0.50.60.30.30.30.20.3-0.80.20.30.10.1-0.3-0.3-0.10.20.0
Indifference point function ln k0.20.31.10.6-0.60.10.00.30.3-0.4-0.10.40.40.50.80.60.50.80.60.71.10.6-0.6-0.7-0.50.80.8
Indifference point function log k0.20.31.10.6-0.60.10.00.30.3-0.4-0.10.40.40.50.80.60.50.80.60.71.10.6-0.6-0.7-0.50.80.8
Patch foraging total patch changes 0 sec0.30.52.9-1.71.7-1.3-1.20.60.2-0.5-0.70.50.60.3-0.00.20.2-1.10.20.1-0.1-0.0-0.0-0.1-0.00.0-0.1
Patch foraging total patch changes 12 sec0.20.31.80.4-0.40.20.0-0.3-0.00.3-0.3-0.7-0.5-0.4-0.8-0.6-0.4-0.0-0.4-0.7-1.3-0.40.80.70.1-0.6-0.3
Patch foraging total patch changes 18 sec0.20.31.0-0.60.6-0.6-0.5-0.0-0.20.0-0.2-0.4-0.3-0.2-0.5-0.3-0.2-0.7-0.2-0.7-1.0-0.40.80.80.1-0.8-0.5
Patch foraging total patch changes 24 sec0.71.27.1-2.72.7-1.9-1.70.80.6-0.8-1.00.70.50.30.10.10.2-1.80.10.0-0.5-0.20.00.0-0.0-0.2-0.3
Patch foraging total patch changes 6 sec0.20.42.0-1.41.4-0.5-0.3-0.10.10.1-0.10.1-0.3-0.3-0.2-0.5-0.4-1.2-0.5-0.3-0.5-0.60.30.40.5-0.5-0.8
Patch foraging time to switch 0 sec0.00.10.70.8-0.80.30.0-0.00.4-0.0-0.1-0.2-0.10.10.00.00.10.60.2-0.0-0.40.20.1-0.0-0.30.10.3
Patch foraging water rate 0 sec0.61.31.8-1.11.0-1.3-1.31.31.1-1.3-1.31.31.31.11.11.11.10.21.11.11.21.0-1.2-1.1-1.01.11.0
Patch foraging water rate 12 sec0.10.10.6-0.50.6-0.3-0.0-0.20.50.20.70.3-0.2-0.30.0-0.2-0.3-0.8-0.30.20.1-0.4-0.3-0.20.50.1-0.2
Patch foraging water rate 18 sec1.11.72.80.5-0.41.41.5-1.6-0.91.61.7-1.0-1.4-1.5-1.5-1.5-1.5-0.8-1.5-1.3-1.2-1.41.21.31.5-1.4-1.4
Patch foraging water rate 24 sec0.60.91.60.5-0.51.10.8-1.1-0.61.11.1-0.8-1.2-1.2-0.8-1.3-1.2-0.4-1.1-0.8-1.3-1.20.70.91.0-0.8-0.7
Patch foraging water rate 6 sec0.30.51.4-0.20.2-0.2-0.20.60.8-0.6-0.50.80.40.60.90.70.70.50.61.01.20.7-1.1-0.9-0.60.90.6
Seeking ratio, delayed vs. immediate footshock0.50.61.20.9-0.90.80.9-0.8-0.80.81.1-0.8-0.7-0.7-0.7-0.5-0.6-0.0-0.6-1.00.2-0.51.10.90.6-0.8-0.5
Distance traveled before self-admin1.51.910.3-3.23.2-2.9-2.20.90.9-0.8-0.60.70.60.1-0.00.20.2-2.50.10.7-0.7-0.4-0.6-0.60.10.5-0.2
Distance traveled after self-admin0.20.20.40.2-0.10.50.5-0.5-0.30.50.4-0.6-0.6-0.5-0.6-0.6-0.6-0.2-0.5-0.0-0.6-0.60.10.00.50.0-0.4
Extensor digitorum longus weight0.83.35.70.2-0.01.01.4-2.0-1.92.02.4-1.8-1.7-2.1-1.9-1.9-2.1-1.8-2.1-1.8-1.4-2.11.81.82.2-1.9-1.9
Bone: elastic displacement0.80.92.90.7-0.80.1-0.00.70.8-0.7-0.51.01.00.91.01.00.91.31.01.01.71.1-1.1-1.0-0.91.10.9
Bone: elastic work0.00.00.40.1-0.10.10.10.10.1-0.10.00.30.30.10.20.10.10.10.10.10.60.1-0.1-0.1-0.00.10.1
Bone: endosteal estimation0.51.25.0-1.92.0-0.8-0.3-0.5-0.30.50.6-0.6-0.7-0.9-0.9-0.9-0.9-2.2-1.0-0.8-1.1-1.20.70.81.2-0.9-1.2
Bone: endosteal perimeter1.02.14.0-0.81.00.20.6-1.3-1.11.31.5-1.4-1.4-1.6-1.6-1.6-1.6-2.0-1.6-1.5-1.6-1.71.51.51.7-1.6-1.6
Epididymis fat weight0.10.52.51.5-1.60.3-0.20.3-0.0-0.3-0.3-0.20.10.40.50.40.51.40.60.5-0.20.5-0.3-0.5-0.80.71.0
Delta time in closed arm before/after self-admin4.34.06.1-0.0-0.1-2.0-2.32.21.9-2.2-2.11.82.42.12.02.22.21.52.32.01.42.1-2.0-2.0-2.32.12.5
Delta time in open arm before/after self-admin0.60.61.61.2-1.20.1-0.10.40.2-0.4-0.30.50.70.60.60.70.61.30.70.90.90.8-1.0-1.0-0.71.00.9
Diff in mean of infusions in LGA sessions0.50.62.6-1.41.4-0.7-0.5-0.3-0.20.30.4-0.3-0.5-0.7-0.6-0.7-0.7-1.6-0.7-0.5-1.1-0.90.50.50.8-0.6-0.8
Delay discount exponential model param0.30.32.21.5-1.50.70.4-0.4-0.70.30.4-0.7-0.2-0.1-0.1-0.1-0.10.8-0.0-0.3-0.1-0.00.30.2-0.1-0.20.1
Extinction: sum of active levers before priming0.50.53.21.7-1.80.70.30.10.3-0.2-0.3-0.10.10.40.40.30.41.70.50.4-0.10.6-0.4-0.4-0.80.50.9
Active lever presses in extinction session 60.50.51.20.6-0.61.11.0-0.8-0.50.80.8-0.5-0.8-0.8-0.8-0.9-0.8-0.1-0.8-0.4-0.4-0.80.30.50.8-0.4-0.7
Bone: final force0.10.11.1-0.20.2-0.00.10.30.1-0.3-0.20.10.50.30.70.40.30.20.30.21.00.4-0.2-0.2-0.20.20.3
Bone: final moment0.10.10.9-0.40.4-0.10.00.30.1-0.3-0.10.10.40.30.60.30.2-0.00.20.20.90.3-0.1-0.2-0.10.10.2
Food consumed during 24 hour testing period0.30.40.60.1-0.1-0.7-0.70.80.4-0.8-0.80.30.70.70.60.80.80.50.80.50.80.7-0.5-0.5-0.80.50.8
Glucose0.10.21.41.1-1.20.60.20.0-0.1-0.10.0-0.20.00.20.40.10.21.00.30.30.10.3-0.4-0.3-0.40.40.5
Heart weight0.20.21.60.4-0.50.70.8-0.01.30.00.00.40.10.30.30.30.20.60.20.31.20.4-0.3-0.2-0.10.2-0.2
Delay discount hyperbolic model param0.20.31.51.2-1.20.60.4-0.4-0.70.40.4-0.8-0.3-0.3-0.2-0.2-0.20.6-0.1-0.4-0.2-0.20.40.40.1-0.3-0.0
Intermittent access intake day 1-15 change0.30.62.6-1.61.6-1.4-1.00.80.9-0.7-0.70.70.80.50.20.50.5-0.90.40.60.30.3-0.5-0.5-0.30.40.2
Intermittent access intake escalation0.30.73.3-1.81.8-1.7-1.30.80.8-0.7-0.70.60.70.40.00.40.4-1.20.30.5-0.10.1-0.4-0.4-0.20.30.2
Intermittent access intake escalation 20.10.10.4-0.50.5-0.3-0.1-0.1-0.30.20.1-0.1-0.1-0.3-0.6-0.3-0.3-0.6-0.3-0.4-0.6-0.30.40.40.3-0.5-0.4
Intermitt. access day 1 inactive lever presses0.00.00.20.0-0.00.20.30.1-0.1-0.1-0.10.20.10.20.20.10.10.20.10.20.50.2-0.0-0.2-0.10.2-0.0
Intermitt. access day 15 inactive lever presses0.91.84.20.0-0.1-0.3-0.21.31.7-1.3-1.41.41.51.41.51.41.41.41.41.52.01.6-1.4-1.5-1.31.41.2
Intermitt. access escalation Index0.91.21.91.0-1.01.31.3-1.2-1.01.21.3-1.4-1.2-1.2-1.3-1.1-1.1-0.2-1.1-1.1-1.0-1.01.01.11.0-1.1-0.9
Intermittent access day 1 total infusions3.86.115.6-4.03.9-3.8-3.22.82.4-2.7-2.52.82.42.22.32.22.2-1.21.92.11.91.8-1.9-1.9-1.71.91.4
Intermittent access day 15 total infusions2.94.317.4-4.24.1-3.7-2.92.21.9-2.1-1.92.01.81.51.41.51.5-2.11.21.31.00.9-1.1-1.2-0.91.10.8
Intermittent access terminal intake (last 3 days)3.95.115.8-4.03.9-3.6-2.82.42.2-2.3-2.02.52.31.91.82.01.9-1.51.61.91.81.4-1.7-1.7-1.21.61.0
Intermittent access total infusions5.66.617.4-4.24.1-4.1-3.32.82.5-2.7-2.42.72.62.22.32.32.2-1.41.92.22.01.7-2.0-2.0-1.62.01.5
Intermittent access day 1 locomotion5.77.217.6-4.24.1-4.2-3.63.02.8-2.9-2.82.92.62.32.42.32.4-1.32.12.21.81.8-2.1-2.1-1.82.01.7
Intermittent access day 15 total locomotion2.54.526.2-5.15.1-4.1-3.01.71.6-1.6-1.31.61.30.80.70.80.8-3.40.40.80.30.1-0.6-0.7-0.00.50.1
Intermittent access total locomotion4.95.928.7-5.45.4-4.5-3.42.22.2-2.1-1.82.21.91.31.31.41.3-3.11.01.50.80.6-1.3-1.4-0.61.10.5
Intermittent access standard deviation0.30.62.5-1.11.1-1.6-1.50.90.7-0.9-0.60.60.90.60.50.60.6-0.50.60.70.10.4-0.7-0.7-0.50.70.6
Left kidney weight0.41.74.31.5-1.60.1-0.40.91.8-1.0-0.90.71.31.21.11.31.32.11.41.31.31.5-1.1-1.4-1.51.41.5
Right kidney weight0.73.17.71.9-2.0-0.0-0.61.42.4-1.4-1.40.91.61.81.61.81.82.82.01.61.92.0-1.5-1.7-2.11.82.1
Cocaine induced anxiety0.40.64.22.0-2.01.00.5-0.2-0.30.10.0-0.20.10.20.10.20.21.60.3-0.10.10.40.30.0-0.50.10.6
Post-drug Anxiety0.30.32.21.5-1.50.70.5-0.5-0.80.50.7-0.5-0.2-0.3-0.2-0.2-0.30.6-0.2-0.2-0.2-0.20.20.10.10.00.2
Baseline Anxiety0.10.10.3-0.00.10.20.4-0.3-0.50.30.5-0.2-0.2-0.4-0.2-0.3-0.3-0.3-0.40.10.1-0.3-0.2-0.10.50.1-0.2
Tail length0.10.62.31.2-1.11.20.8-0.7-1.50.70.6-0.8-0.9-0.6-0.2-0.7-0.60.4-0.5-0.6-0.4-0.50.60.60.5-0.5-0.3
Length with tail0.00.11.60.5-0.50.40.2-0.1-1.30.0-0.0-0.3-0.10.00.30.00.00.50.1-0.20.20.10.30.3-0.1-0.30.2
Length without tail0.41.27.5-2.72.7-1.9-1.50.9-0.3-0.8-0.80.80.70.40.50.40.4-1.60.20.20.20.1-0.2-0.2-0.10.00.1
Times rat made contact with spout2.52.94.2-1.21.1-2.0-2.01.91.9-1.9-1.61.71.91.81.81.91.80.41.71.71.71.6-1.7-1.7-1.61.71.5
Lifetime Intake6.37.617.5-4.03.9-4.2-3.63.12.7-3.0-2.72.92.92.52.62.62.5-1.02.32.42.22.1-2.3-2.3-2.02.21.9
Liver weight, left1.82.94.70.2-0.11.01.2-1.8-2.01.81.8-1.8-1.8-2.0-2.2-1.9-1.9-1.5-1.9-1.6-2.1-2.01.61.61.9-1.6-1.8
Liver weight, right0.81.44.22.0-2.01.91.6-1.3-1.71.31.1-1.1-1.2-1.0-0.9-1.0-1.00.8-0.9-0.7-0.9-0.70.80.70.7-0.6-0.6
Locomotor activity3.45.215.5-3.53.4-3.9-3.52.51.7-2.4-2.12.62.31.92.02.01.9-1.41.71.91.31.4-2.0-1.9-1.41.71.3
Locomotor testing distance3.25.88.5-1.81.7-2.9-2.92.72.1-2.6-2.42.82.72.52.62.62.50.42.42.62.22.3-2.6-2.5-2.22.42.1
Locomotor testing rearing1.22.44.3-2.02.0-2.0-1.91.61.3-1.6-1.72.11.71.51.41.41.4-0.31.31.71.11.2-1.7-1.6-1.11.40.9
Locomotion in novel chamber1.72.14.90.3-0.11.11.7-1.7-1.81.72.2-1.1-1.3-1.6-1.6-1.3-1.6-1.3-1.6-1.2-0.2-1.41.41.31.9-1.4-1.8
Locomotion in novel chamber post-restriction0.30.52.21.1-1.10.50.60.20.3-0.3-0.10.40.70.60.50.80.61.20.60.51.50.9-0.5-0.5-0.60.50.6
Fecal boli incidents, locomotor time 10.10.10.4-0.20.2-0.6-0.60.40.7-0.4-0.60.10.50.30.10.40.40.00.40.3-0.00.3-0.5-0.3-0.40.30.4
Change in fecal boli incidents, locomotor task1.31.33.00.6-0.61.51.7-1.4-1.31.41.5-0.8-1.3-1.2-0.8-1.2-1.2-0.4-1.2-1.0-0.2-1.01.01.11.2-1.0-1.3
Time >=10cm from walls, locomotor time 11.21.32.61.4-1.31.11.1-1.3-0.81.31.6-1.3-0.9-1.1-1.1-0.9-1.1-0.2-1.0-1.3-0.5-1.01.41.31.0-1.2-1.0
Bouts of movement, locomotor time 10.91.02.50.3-0.3-0.2-0.40.91.5-0.9-1.30.80.81.00.70.80.91.20.91.40.31.0-1.6-1.3-1.11.31.2
Total resting periods, locomotor time 11.71.93.8-0.30.3-1.0-1.11.41.9-1.4-1.81.21.31.41.11.31.41.01.31.80.61.4-2.0-1.7-1.41.71.5
Rest time, locomotor task time 10.50.63.2-1.71.8-1.6-1.20.40.3-0.3-0.4-0.20.0-0.1-0.4-0.0-0.0-1.5-0.20.2-1.0-0.3-0.4-0.10.20.1-0.1
Distance moved, locomotor task time 10.30.51.40.7-0.61.01.0-0.9-0.90.91.2-0.5-0.6-0.7-0.6-0.6-0.7-0.1-0.7-0.60.1-0.60.60.50.8-0.6-0.8
Vertical activity count, locomotor time 10.71.64.52.1-2.12.01.7-1.5-1.51.41.6-1.1-1.2-1.1-0.9-1.1-1.10.6-1.0-0.8-0.5-0.90.80.60.9-0.7-0.7
Time >=10cm from walls, locomotor time 20.20.32.41.5-1.60.80.5-0.20.20.10.2-0.4-0.10.10.30.10.11.10.2-0.10.50.3-0.00.1-0.30.10.4
Bouts of movement, locomotor time 22.84.56.2-0.20.1-2.1-2.42.42.2-2.4-2.42.02.52.31.92.42.41.52.42.11.52.3-2.1-2.2-2.42.22.3
Total resting periods, locomotor time 23.56.18.3-0.20.1-2.4-2.72.72.5-2.7-2.72.42.92.72.32.82.81.82.82.61.92.7-2.6-2.6-2.82.62.7
Rest time, locomotor task time 20.20.20.8-0.50.5-0.3-0.0-0.4-0.40.40.4-0.4-0.5-0.5-0.5-0.5-0.5-0.8-0.5-0.2-0.9-0.60.10.30.5-0.3-0.5
Distance moved, locomotor task time 20.00.00.3-0.20.20.30.4-0.10.20.10.30.10.00.00.00.0-0.0-0.1-0.10.30.60.0-0.3-0.30.20.2-0.2
Vertical activity count, locomotor time 20.10.10.30.4-0.40.60.4-0.4-0.30.40.4-0.4-0.4-0.3-0.4-0.4-0.30.0-0.3-0.2-0.3-0.30.10.20.3-0.3-0.3
Light reinforcement 10.10.30.6-0.00.10.50.8-0.7-0.20.70.7-0.2-0.6-0.7-0.7-0.6-0.7-0.5-0.7-0.5-0.3-0.60.30.60.8-0.6-0.8
Light reinforcement 21.72.55.41.9-1.82.22.3-1.9-1.81.82.1-1.5-1.7-1.5-1.6-1.4-1.50.1-1.5-1.5-0.7-1.21.31.41.4-1.4-1.3
Bone: marrow area0.51.24.8-1.81.9-0.7-0.3-0.5-0.40.60.7-0.6-0.7-1.0-0.9-0.9-1.0-2.2-1.1-0.8-1.2-1.20.80.91.2-1.0-1.2
Bone: maximum diameter4.07.511.3-0.70.91.11.5-2.7-2.42.83.0-2.7-2.8-3.1-2.9-3.1-3.1-3.2-3.1-2.9-3.0-3.42.92.93.2-2.9-3.0
Bone: maximum force0.10.20.4-0.60.60.00.3-0.2-0.30.20.4-0.4-0.1-0.40.0-0.3-0.4-0.7-0.4-0.40.2-0.40.50.40.5-0.5-0.4
Bone: maximum moment0.10.20.8-0.80.9-0.10.2-0.2-0.30.20.4-0.3-0.1-0.4-0.1-0.3-0.4-0.9-0.5-0.50.2-0.50.50.50.6-0.5-0.4
Mean time between licks in bursts0.10.20.80.7-0.70.50.40.00.7-0.1-0.1-0.00.20.40.50.40.30.90.30.40.60.5-0.5-0.4-0.40.30.3
Mean num. licks in bursts0.00.00.30.2-0.2-0.5-0.3-0.0-0.30.00.5-0.10.2-0.10.10.20.0-0.30.0-0.00.2-0.10.00.00.10.10.2
Cd content in liver7.48.211.00.20.01.82.2-3.0-2.53.03.0-2.9-3.2-3.2-3.2-3.2-3.2-2.5-3.2-3.0-3.3-3.32.93.03.2-3.1-3.1
Co content in liver0.20.30.50.0-0.00.40.4-0.5-0.70.50.5-0.5-0.6-0.6-0.4-0.6-0.6-0.3-0.6-0.7-0.6-0.60.60.70.5-0.6-0.5
Cu content in liver0.70.93.1-1.51.5-0.4-0.1-0.5-0.60.60.5-0.4-0.8-0.9-0.6-1.0-0.9-1.8-1.0-0.7-1.0-1.20.70.81.1-0.8-1.1
Fe content in liver0.70.81.30.2-0.10.70.8-1.1-0.91.11.1-0.8-1.1-1.2-1.0-1.1-1.1-0.8-1.1-0.6-1.1-1.10.50.61.1-0.7-0.9
K content in liver0.50.52.5-1.61.5-1.1-0.80.80.4-0.7-0.50.80.80.50.50.50.5-0.70.40.40.70.4-0.2-0.4-0.20.30.1
Mg content in liver1.41.42.7-1.31.2-1.6-1.61.41.2-1.4-1.31.31.41.11.21.21.2-0.01.11.10.91.0-1.0-1.1-1.01.11.0
Mn content in liver0.91.04.1-2.02.0-1.7-1.41.11.2-1.0-1.00.91.00.80.60.80.8-0.90.70.50.70.5-0.4-0.5-0.50.40.3
Na content in liver0.30.31.3-1.21.1-1.1-1.10.70.2-0.6-0.70.50.50.40.40.40.4-0.50.40.30.10.2-0.3-0.2-0.30.20.3
Rb content in liver0.40.51.2-0.10.1-0.5-0.40.60.3-0.6-0.40.90.90.70.70.80.70.40.70.91.10.7-0.8-0.9-0.50.90.6
Se content in liver0.20.21.2-1.11.1-0.8-0.60.3-0.3-0.3-0.30.30.20.10.10.20.1-0.70.10.10.00.0-0.1-0.10.00.0-0.1
Sr content in liver0.40.32.3-1.51.5-0.6-0.20.4-0.0-0.4-0.40.30.30.20.50.20.2-0.80.00.20.90.1-0.2-0.10.10.1-0.0
Zn content in liver4.34.810.1-1.81.90.30.9-1.9-2.51.92.1-1.7-2.1-2.4-2.1-2.4-2.4-3.2-2.5-2.1-2.4-2.72.12.12.6-2.2-2.7
Bone: minimum diameter0.71.23.6-1.31.4-0.20.2-0.7-0.50.80.9-1.0-0.9-1.1-0.9-1.1-1.1-1.9-1.2-1.2-0.8-1.31.31.31.3-1.3-1.2
Time in familiar zone, hab. session 10.20.20.6-0.10.10.10.2-0.5-0.10.50.8-0.2-0.2-0.4-0.3-0.3-0.4-0.6-0.4-0.50.0-0.40.50.40.5-0.5-0.5
Time in novel zone, hab. session 11.01.01.6-0.70.6-0.9-1.01.20.1-1.1-1.21.01.01.11.11.01.10.51.01.30.91.0-1.3-1.2-1.01.21.0
Total zone transitions, hab. session 11.82.65.7-2.01.9-2.1-2.21.82.4-1.8-1.91.91.61.51.41.31.5-0.31.41.50.91.2-1.4-1.4-1.31.41.0
Total locomotion distance, hab. session 12.12.94.6-1.00.9-1.9-2.11.91.7-1.9-1.91.81.91.91.61.81.80.61.81.81.31.7-1.8-1.8-1.71.81.5
Locomotion velocity, hab. session 11.72.44.2-0.90.8-1.7-2.11.81.9-1.8-1.81.61.71.71.41.61.70.61.71.60.91.5-1.5-1.5-1.71.51.4
Time in familiar zone, hab. session 22.32.43.9-0.20.31.01.4-1.7-1.41.72.0-1.2-1.6-1.8-1.7-1.7-1.8-1.6-1.8-1.5-1.3-1.81.41.51.9-1.5-1.8
Time in novel zone, hab. session 21.61.62.4-0.30.2-0.9-1.11.41.0-1.4-1.61.31.21.41.51.31.41.01.41.41.21.4-1.4-1.4-1.41.41.3
Total zone transitions, hab. session 21.41.85.1-0.70.6-1.0-1.31.52.3-1.4-1.71.51.21.41.51.21.40.71.41.41.01.3-1.4-1.3-1.31.41.2
Total locomotion distance, hab. session 22.33.15.3-1.11.0-1.6-1.92.02.3-1.9-2.11.91.81.91.91.71.80.81.81.91.51.7-1.9-1.8-1.71.81.6
Locomotion velocity, hab. session 22.33.04.9-1.31.2-1.7-1.92.02.2-1.9-2.11.91.81.81.81.71.80.61.81.91.41.6-1.9-1.8-1.71.81.5
Novel to familiar place preference ratio1.71.95.8-0.80.7-0.6-0.51.41.1-1.4-1.51.71.51.61.71.51.50.91.41.42.41.6-1.5-1.4-1.21.31.1
Novelty place preference1.11.25.4-0.80.8-0.2-0.11.00.8-1.0-1.11.51.11.21.41.21.10.61.01.12.31.3-1.1-1.0-0.80.90.6
Time in novel zone, NPP test1.51.65.8-1.41.3-0.7-0.41.31.1-1.2-1.31.81.31.41.61.31.20.31.11.32.41.3-1.4-1.2-0.91.10.7
Total zone transitions, NPP test0.71.04.3-0.70.6-1.2-1.51.22.1-1.2-1.31.00.91.00.90.81.00.31.00.70.20.8-0.7-0.6-1.10.80.9
Total locomotion distance, NPP test3.14.25.6-0.1-0.1-1.6-2.12.22.3-2.3-2.31.92.12.32.22.22.31.72.32.21.72.2-2.2-2.1-2.42.32.3
Locomotion velocity, NPP test2.33.24.60.3-0.4-1.3-1.81.91.9-2.0-2.01.51.82.01.91.92.01.82.11.81.42.0-1.8-1.8-2.21.92.1
Intraocular pressure0.00.00.10.3-0.3-0.0-0.00.1-0.2-0.1-0.1-0.10.10.00.10.10.10.20.1-0.10.10.10.10.0-0.10.00.3
Delta distance traveled before/after self-admin1.61.78.52.9-2.92.82.1-1.1-0.91.00.7-0.9-0.7-0.4-0.4-0.6-0.52.1-0.3-0.50.0-0.00.50.50.1-0.3-0.1
Delta ambulatory time before/after self-admin2.02.413.03.6-3.63.22.4-1.3-1.21.20.9-1.1-0.9-0.5-0.4-0.7-0.62.5-0.4-0.5-0.0-0.10.50.50.1-0.30.0
Parametrial fat weight0.30.82.41.6-1.61.30.9-0.80.30.80.6-1.2-0.9-0.7-0.7-0.8-0.60.6-0.5-0.9-0.8-0.60.90.80.3-0.7-0.2
Pavlov. Cond. lever latency0.50.72.7-0.30.2-0.00.20.61.4-0.6-0.70.90.80.90.80.90.80.60.70.91.71.0-0.9-0.9-0.60.80.3
Pavlov. Cond. magazine entry latency0.10.20.70.5-0.50.0-0.10.1-0.9-0.10.20.30.40.20.40.30.20.40.30.40.80.3-0.3-0.4-0.20.40.4
Pavlov. Cond. change in total contacts0.50.53.11.7-1.80.3-0.30.2-0.6-0.2-0.1-0.30.40.40.40.40.41.40.60.4-0.00.5-0.2-0.4-0.80.61.2
Pavlov. Cond. index score0.30.42.10.2-0.10.20.1-0.6-1.50.60.9-0.5-0.5-0.7-0.5-0.6-0.7-0.6-0.6-0.5-0.6-0.80.60.60.6-0.5-0.4
Pavlov. Cond. latency score0.30.32.00.1-0.10.0-0.0-0.5-1.40.50.7-0.5-0.5-0.6-0.5-0.6-0.6-0.6-0.5-0.5-0.7-0.70.60.50.6-0.5-0.3
Pavlov. Cond. lever contacts0.70.92.60.4-0.40.30.1-0.8-1.60.80.9-1.1-0.9-1.0-1.0-1.0-0.9-0.6-0.9-1.1-1.6-1.11.11.10.8-0.9-0.5
Pavlov. Cond. magazine entry number0.10.11.0-0.40.4-0.2-0.10.21.0-0.2-0.5-0.00.00.1-0.10.00.1-0.10.1-0.2-0.30.10.20.2-0.1-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.30.31.2-0.50.6-0.3-0.3-0.20.70.30.0-0.6-0.5-0.5-0.7-0.6-0.5-0.8-0.5-0.7-1.1-0.70.60.70.4-0.7-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.62.30.4-0.40.40.4-0.8-1.50.81.1-0.8-0.7-0.9-0.7-0.8-0.8-0.5-0.8-0.7-0.7-0.90.80.70.8-0.6-0.5
Pavlov. Cond. response bias0.40.52.91.0-0.90.60.4-0.7-1.70.71.0-0.7-0.6-0.7-0.5-0.6-0.60.1-0.5-0.5-0.5-0.60.50.50.5-0.4-0.1
Pavlov. Cond. lever latency0.20.21.1-1.01.0-1.0-0.80.50.3-0.5-0.30.40.30.20.50.30.2-0.70.20.30.30.1-0.2-0.3-0.10.30.2
Pavlov. Cond. magazine entry latency1.21.42.21.0-0.91.41.3-1.3-0.81.31.2-1.5-1.2-1.2-1.3-1.3-1.2-0.3-1.2-1.4-1.2-1.11.31.31.1-1.3-1.2
Pavlov. Cond. change in total contacts0.10.20.7-0.10.10.60.8-0.5-0.00.50.5-0.1-0.3-0.4-0.5-0.4-0.5-0.3-0.5-0.3-0.1-0.40.20.30.5-0.5-0.7
Pavlov. Cond. index score0.50.71.00.7-0.71.01.0-1.0-0.60.90.8-1.0-0.8-0.8-1.0-0.9-0.8-0.1-0.8-0.9-0.8-0.70.80.80.7-0.9-0.9
Pavlov. Cond. latency score0.50.71.00.3-0.30.80.9-0.9-0.80.90.8-1.0-0.8-0.8-1.0-0.9-0.9-0.4-0.9-1.0-0.9-0.80.90.90.8-1.0-1.0
Pavlov. Cond. lever contacts0.50.71.91.3-1.31.41.3-0.9-0.50.90.7-0.9-0.7-0.6-0.9-0.7-0.70.5-0.6-0.8-0.7-0.50.70.80.5-0.8-0.6
Pavlov. Cond. magazine entry number1.51.92.7-0.60.5-1.3-1.41.50.7-1.5-1.41.51.41.51.61.51.50.81.51.61.41.4-1.5-1.5-1.41.61.6
Pavlov. Cond. intertrial magazine entries8.412.616.9-1.61.3-3.1-3.43.83.8-3.8-3.63.93.83.94.13.93.81.93.83.93.73.7-3.8-3.9-3.53.93.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.5-0.40.80.8-0.8-0.40.80.7-0.8-0.6-0.7-0.8-0.7-0.7-0.2-0.7-0.7-0.7-0.60.60.70.6-0.8-0.8
Pavlov. Cond. response bias0.81.12.81.7-1.61.71.5-1.2-0.31.11.0-1.2-1.0-0.9-1.1-0.9-0.90.6-0.8-0.9-0.9-0.60.80.90.6-0.9-0.7
Time in closed arm before self-admin0.20.21.5-1.21.20.00.3-0.00.20.10.10.20.1-0.1-0.0-0.2-0.2-0.8-0.3-0.20.6-0.20.30.20.4-0.3-0.6
Time in closed arm after self-admin2.12.33.8-0.70.6-1.6-1.81.71.6-1.7-1.71.51.91.71.51.71.60.71.61.41.21.6-1.4-1.5-1.61.41.6
Time in open arm before self-admin1.51.72.6-0.70.80.61.0-1.3-1.21.31.3-1.1-1.5-1.4-1.2-1.4-1.4-1.6-1.5-1.3-1.2-1.51.21.31.6-1.4-1.6
Time in open arm after self-admin0.70.72.81.5-1.51.61.7-0.9-1.00.91.0-0.8-0.8-0.6-0.4-0.4-0.50.7-0.5-0.30.5-0.20.30.30.5-0.3-0.4
Bone: periosteal estimation1.12.25.4-1.31.40.10.6-1.3-1.31.31.6-1.3-1.3-1.6-1.4-1.5-1.6-2.3-1.7-1.5-1.2-1.81.51.61.9-1.6-1.8
Bone: periosteal perimeter1.52.53.6-0.20.40.60.9-1.6-1.31.61.8-1.6-1.6-1.8-1.7-1.7-1.8-1.8-1.8-1.8-1.7-1.91.81.81.8-1.8-1.6
Bone: post-yield work0.60.92.4-0.50.6-0.2-0.0-0.8-1.10.80.9-0.9-0.9-1.1-0.9-1.0-1.0-1.3-1.0-1.1-1.5-1.21.11.11.0-1.1-0.8
Progressive ratio test 1 active lever presses6.58.117.1-4.14.0-4.1-3.63.23.1-3.1-2.93.02.82.72.72.72.7-0.92.42.42.22.2-2.3-2.3-2.12.21.9
Progressive ratio test 1 breakpoint6.37.717.6-4.24.1-4.0-3.43.13.1-3.0-2.82.92.72.62.62.62.6-1.02.32.42.22.1-2.3-2.2-2.02.11.7
Progressive ratio test 1 inactive lever presses2.53.66.1-2.52.4-2.1-1.72.12.3-2.0-2.12.11.81.91.91.91.8-0.21.61.92.21.7-1.8-1.7-1.41.61.2
Progressive ratio test 2 active lever presses3.54.120.5-4.54.5-3.5-2.62.01.9-1.9-1.72.01.71.41.31.31.3-2.31.01.01.10.8-0.9-0.9-0.60.70.4
Progressive ratio test 2 breakpoint3.54.020.6-4.54.5-3.4-2.51.91.8-1.8-1.72.01.61.31.31.31.2-2.40.91.01.10.8-0.9-0.9-0.50.70.3
Progressive ratio test 2 inactive lever presses2.64.311.7-3.43.4-3.1-2.52.22.3-2.2-2.02.42.11.81.81.81.7-1.21.51.81.71.4-1.7-1.6-1.21.51.1
Incentive Sensitization - Responses1.11.611.3-3.33.4-2.2-1.40.70.5-0.6-0.60.80.60.20.20.20.1-2.4-0.1-0.00.2-0.20.20.20.4-0.3-0.5
Incentive Sensitization - Breakpoint1.21.510.5-3.23.2-2.2-1.40.80.6-0.7-0.60.90.60.30.30.30.2-2.3-0.00.00.2-0.10.10.10.3-0.2-0.4
Sum of active levers in priming session hrs 5-63.23.04.92.2-2.12.22.0-1.9-1.71.91.8-2.0-1.9-1.8-1.7-1.7-1.70.2-1.6-1.6-1.6-1.51.71.61.4-1.5-1.2
Progressive ratio2.03.25.4-1.11.20.20.7-1.5-1.51.51.6-1.8-1.8-1.9-2.1-1.8-1.8-2.3-1.9-2.0-2.1-2.02.12.01.9-2.1-2.0
Food seeking constrained by brief footshock1.41.89.6-3.13.1-2.3-1.91.21.1-1.1-0.91.20.70.61.00.60.6-1.80.40.70.40.2-0.9-0.6-0.20.40.2
Seeking ratio, punishment vs. effort1.92.74.5-0.50.4-1.3-1.61.81.5-1.8-1.71.91.71.82.11.71.71.01.81.81.81.7-2.0-1.8-1.71.81.7
Retroperitoneal fat weight0.10.53.41.8-1.81.10.6-0.1-0.10.10.0-0.6-0.20.20.40.20.21.60.4-0.20.50.40.30.1-0.5-0.10.4
Reaction time number correct0.20.41.40.7-0.70.2-0.00.40.4-0.5-0.30.70.60.60.70.70.61.00.70.71.20.7-0.6-0.6-0.70.80.8
Reaction time mean minus median0.00.10.30.4-0.40.10.0-0.0-0.40.0-0.2-0.5-0.20.1-0.3-0.00.00.30.1-0.3-0.40.10.40.2-0.2-0.2-0.0
Reaction time mean minus median AUC0.20.51.00.4-0.40.91.0-0.8-1.00.70.5-1.0-0.7-0.6-0.7-0.6-0.6-0.0-0.6-0.9-0.4-0.51.00.80.5-0.9-0.8
Reaction time num false alarms0.10.10.30.4-0.4-0.4-0.50.20.1-0.2-0.3-0.10.30.2-0.00.20.20.20.30.1-0.30.20.0-0.2-0.30.20.5
Reaction time num false alarms AUC0.10.20.80.9-0.9-0.1-0.30.2-0.1-0.2-0.3-0.20.40.20.00.30.30.70.30.2-0.20.3-0.0-0.3-0.50.40.7
Reaction time trials correct on left0.20.41.40.7-0.70.2-0.00.40.4-0.5-0.30.70.60.60.70.70.61.00.70.71.20.7-0.6-0.6-0.70.80.8
Reaction time trials on left0.20.41.40.7-0.80.20.00.40.4-0.4-0.30.70.50.60.70.70.61.00.70.71.20.7-0.6-0.6-0.70.80.8
Reaction time mean0.50.81.40.4-0.31.01.2-1.0-0.51.01.0-1.1-1.0-0.9-1.0-0.9-0.9-0.4-0.9-0.8-0.6-0.80.90.80.9-0.9-1.2
Reaction time mean AUC0.50.81.50.5-0.41.11.2-1.0-0.51.01.0-1.2-1.0-0.9-0.9-0.9-0.9-0.3-0.9-0.9-0.6-0.80.90.80.9-0.9-1.1
Median of all reaction times0.70.91.80.3-0.21.11.3-1.1-0.41.11.2-1.1-1.0-1.1-1.0-1.1-1.1-0.6-1.1-0.8-0.6-1.00.80.81.1-0.9-1.3
Reaction time omissions0.10.20.60.4-0.50.0-0.00.3-0.0-0.3-0.30.10.40.50.50.50.50.70.50.40.40.6-0.5-0.5-0.60.30.3
Reaction time false alarm rate0.10.10.40.1-0.1-0.2-0.2-0.1-0.40.1-0.0-0.6-0.1-0.2-0.4-0.2-0.2-0.2-0.2-0.3-0.7-0.20.40.30.1-0.3-0.0
Reaction time premature initiation rate0.20.31.60.5-0.50.60.70.10.4-0.1-0.20.50.40.50.50.50.40.80.40.31.20.7-0.4-0.3-0.30.30.1
Reaction time premature initiations0.20.41.91.0-1.00.80.80.10.4-0.1-0.10.40.30.50.60.60.41.20.50.31.40.8-0.4-0.3-0.40.40.4
Std. dev. reaction times0.10.20.50.1-0.00.40.5-0.4-0.70.40.3-0.7-0.4-0.3-0.5-0.4-0.4-0.2-0.4-0.6-0.2-0.30.60.50.4-0.6-0.6
Reaction time trials completed0.20.41.40.7-0.80.20.00.40.4-0.4-0.30.70.50.60.70.70.61.00.70.71.20.7-0.6-0.6-0.70.80.8
Reaction time trials AUC0.30.51.50.7-0.70.1-0.10.50.5-0.6-0.40.80.60.70.90.80.71.10.80.71.20.8-0.7-0.7-0.80.90.9
Run reversals in cocaine runway, females0.20.21.0-0.90.9-0.6-0.60.1-0.0-0.1-0.30.1-0.0-0.1-0.2-0.2-0.1-0.6-0.1-0.0-1.0-0.30.00.00.0-0.1-0.2
Run reversals in cocaine runway, males0.50.51.40.9-0.91.21.1-0.8-0.70.80.7-0.7-0.9-0.7-0.5-0.8-0.70.2-0.7-0.5-0.5-0.60.40.50.6-0.5-0.4
Latency to leave start box in cocaine runway1.11.22.31.4-1.41.00.9-1.1-1.51.10.9-1.5-1.2-1.0-1.5-0.9-1.00.1-0.9-1.2-1.4-0.91.21.10.7-1.1-0.5
Latency to leave start box in cocaine runway, F1.01.13.71.9-1.91.51.3-1.1-1.21.11.0-1.3-1.0-0.8-1.1-0.7-0.80.7-0.7-0.9-0.8-0.50.90.90.5-0.8-0.3
Latency to leave start box in cocaine runway, M0.20.20.7-0.50.5-0.8-0.70.1-0.4-0.1-0.2-0.2-0.2-0.2-0.6-0.1-0.1-0.6-0.1-0.3-0.9-0.30.30.20.1-0.3-0.0
Std. dev. time between licks in bursts0.40.62.01.4-1.41.20.9-0.8-0.90.70.6-1.1-0.7-0.5-0.3-0.5-0.50.7-0.4-0.6-0.7-0.30.60.60.3-0.5-0.1
Total sessions with >9 infusions3.23.89.6-2.92.8-3.1-2.72.21.9-2.1-1.91.91.91.81.91.81.8-0.81.61.71.41.4-1.7-1.6-1.41.51.3
Short access day 1 total inactive lever presses0.40.52.3-1.31.4-0.8-0.3-0.2-0.10.20.4-0.5-0.3-0.6-0.6-0.5-0.5-1.5-0.6-0.5-0.6-0.70.60.60.7-0.5-0.7
Short access day 10 total inactive lever presses0.92.23.40.3-0.21.11.2-1.5-1.51.61.4-1.5-1.5-1.7-1.9-1.7-1.7-1.2-1.7-1.6-1.6-1.71.81.61.7-1.5-1.5
Short access day 1 total infusions2.23.06.2-2.22.1-2.5-2.31.91.7-1.9-1.71.91.71.71.81.71.7-0.41.51.61.31.4-1.6-1.5-1.41.51.3
Short access day 10 total infusions5.26.610.5-3.12.9-3.2-2.82.92.7-2.8-2.52.82.82.52.72.62.5-0.22.32.62.72.2-2.5-2.5-2.02.41.9
Short access total infusions6.07.712.3-2.92.7-3.5-3.33.22.9-3.1-2.93.03.02.83.02.92.80.22.72.72.52.5-2.6-2.6-2.52.62.3
Short access day 1 locomotion1.01.33.1-1.71.6-1.8-1.71.21.0-1.2-1.11.30.90.91.20.91.0-0.50.91.10.50.7-1.2-1.0-0.81.00.8
Short access day 10 total locomotion1.62.915.1-3.93.9-3.1-2.51.61.5-1.5-1.31.41.20.91.00.90.9-2.20.70.80.60.4-0.7-0.8-0.40.60.2
Short access total locomotion3.03.612.7-3.63.5-3.2-2.72.01.8-1.9-1.71.71.51.41.61.51.5-1.51.31.41.21.0-1.3-1.3-1.01.20.8
One hour access (0.3 mA shock)2.42.88.3-2.92.8-2.5-2.01.81.5-1.7-1.51.91.81.41.51.41.4-1.01.21.41.41.1-1.3-1.3-0.91.10.8
Compulsive drug intake0.81.06.32.5-2.51.71.3-0.6-0.20.50.5-0.3-0.2-0.10.2-0.0-0.11.80.10.40.60.3-0.4-0.4-0.20.50.4
One hour access (shock baseline)2.03.012.4-3.53.5-3.2-2.61.91.5-1.8-1.61.61.71.31.11.31.3-1.71.00.70.80.8-0.6-0.6-0.80.50.7
Social response proportion0.10.20.80.9-0.90.20.00.0-0.4-0.1-0.1-0.3-0.20.20.00.20.20.70.3-0.5-0.10.30.40.4-0.4-0.30.4
Social responses0.20.20.50.6-0.6-0.1-0.20.4-0.2-0.4-0.40.40.30.50.50.60.50.70.50.10.40.6-0.3-0.1-0.60.20.6
Social time0.30.42.00.00.0-0.2-0.1-0.4-1.30.40.3-1.0-0.8-0.6-0.9-0.5-0.5-0.6-0.6-0.7-1.4-0.60.80.60.4-0.5-0.3
Soleus weight0.10.20.5-0.40.3-0.7-0.50.40.3-0.4-0.10.30.50.30.30.50.4-0.20.30.40.70.3-0.3-0.4-0.20.30.3
Bone: stiffness0.00.10.3-0.30.3-0.10.00.20.5-0.2-0.20.10.30.20.40.20.20.00.1-0.00.50.20.1-0.0-0.1-0.00.1
Tibialis anterior weight0.00.00.30.2-0.2-0.1-0.00.0-0.1-0.00.30.00.30.10.20.20.10.00.10.10.50.1-0.1-0.1-0.00.10.2
Time to tail flick, vehicle, before self-admin1.01.04.1-1.51.6-1.0-0.7-0.4-0.40.50.6-0.7-0.7-0.9-1.0-0.9-0.9-2.0-0.9-0.7-1.6-1.20.70.71.0-0.8-0.9
Time to tail flick, vehicle, after self-admin2.12.84.9-1.41.3-1.2-1.41.91.6-1.9-2.12.21.81.92.01.71.80.81.71.71.81.8-1.7-1.6-1.61.61.4
Time to tail flick, test, before self-admin0.20.20.6-0.40.4-0.6-0.80.50.7-0.4-0.40.30.40.30.40.30.3-0.10.30.30.00.2-0.3-0.2-0.30.40.4
Time to tail flick, test, after self-admin3.23.44.8-0.40.3-1.8-2.02.01.7-2.0-1.82.02.21.91.81.91.91.11.92.11.41.8-2.2-2.1-1.92.12.1
Delta time to tail flick, vehicle, before/after SA6.86.59.0-0.1-0.1-1.2-1.62.62.4-2.7-2.82.82.62.93.02.82.92.52.82.72.93.0-2.7-2.6-2.92.72.7
Delta time to tail flick, test, before/after SA0.70.81.70.9-0.9-0.2-0.40.70.5-0.8-0.60.71.10.90.61.01.01.31.00.81.01.1-0.8-0.9-1.10.91.1
Tibia length0.41.02.20.3-0.30.91.0-1.1-1.51.11.1-1.1-1.0-1.1-1.0-1.0-1.1-0.6-1.0-1.1-0.7-1.01.21.11.0-1.0-0.9
Ambulatory time before self-admin1.31.910.3-3.23.2-2.8-2.10.91.1-0.9-0.60.80.60.20.00.30.3-2.40.10.8-0.5-0.3-0.7-0.70.10.6-0.2
Ambulatory time after self-admin0.30.30.70.8-0.80.90.7-0.6-0.40.60.6-0.8-0.6-0.6-0.6-0.6-0.60.2-0.5-0.1-0.6-0.50.10.10.40.0-0.3
Bone: tissue strength0.10.10.2-0.00.00.20.3-0.3-0.30.40.5-0.2-0.3-0.4-0.3-0.3-0.4-0.4-0.4-0.2-0.2-0.40.10.10.4-0.2-0.3
Total heroin consumption0.70.92.81.3-1.31.71.5-1.1-0.81.11.1-0.7-1.0-0.9-0.7-0.9-0.90.3-0.8-0.5-0.0-0.70.50.60.8-0.5-0.7
Bone: trabecular number0.91.58.7-3.03.0-2.1-1.61.01.0-0.9-0.71.00.70.50.70.50.5-1.80.30.40.60.1-0.5-0.4-0.00.20.0
Bone: trabecular spacing1.72.23.91.5-1.52.01.8-1.7-1.31.71.5-1.5-1.7-1.5-1.6-1.6-1.60.0-1.5-1.3-1.7-1.31.31.31.3-1.2-1.2
Bone: trabecular thickness0.30.41.20.3-0.3-0.2-0.20.50.3-0.5-0.40.70.70.60.70.70.60.70.60.61.10.7-0.6-0.6-0.60.70.7
Bone: trabecular tissue density0.10.10.40.6-0.60.60.6-0.3-0.40.30.3-0.4-0.2-0.3-0.3-0.2-0.20.3-0.2-0.30.2-0.10.40.20.2-0.2-0.2
Water consumed over 24 hours0.60.81.7-0.60.5-1.3-1.31.01.3-1.0-0.80.91.00.90.91.00.90.10.90.90.80.8-0.8-0.9-0.80.90.8
Number of responses in last shaping day2.42.66.3-2.01.9-2.5-2.41.91.7-1.8-1.61.41.51.41.61.51.5-0.41.41.61.01.1-1.4-1.6-1.31.51.5