Hub : Genes

Pik3r2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Pik3r2 0.03 0.02 4.0e-03 0.03 0.03 0.02 0.02 3.5e-03 4.1e-03 8.8e-03 1.0e-02
2 PL mRNA stability Pik3r2 0.11 0.06 3.1e-10 0.07 0.1 0.09 0.09 1.1e-07 8.7e-11 2.4e-10 1.9e-10
3 Brain isoform ratio NM_022185.2 0.06 0.04 3.9e-06 0.06 0.06 0.05 0.06 4.3e-06 4.6e-06 1.1e-05 2.4e-06
4 Adipose mRNA stability Pik3r2 0.05 0.03 5.9e-07 0.05 0.05 0.04 0.04 6.8e-06 2.0e-06 4.0e-05 1.0e-05
5 Liver mRNA stability Pik3r2 0.05 0.03 1.4e-05 0.02 0.02 0.01 0.01 2.0e-03 2.1e-03 5.2e-02 8.4e-03
6 Brain gene expression Pik3r2 0.26 0.13 5.6e-17 0.17 0.18 0.17 0.18 5.0e-16 1.9e-16 8.0e-16 1.5e-16
7 NAcc gene expression Pik3r2 0.03 0.02 1.6e-06 0.04 0.04 0.04 0.04 5.5e-07 1.3e-06 1.2e-06 9.8e-07
8 Brain mRNA stability Pik3r2 0.23 0.09 0.0e+00 0.32 0.35 0.35 0.35 2.3e-30 1.8e-33 5.3e-34 5.0e-34
9 LHb gene expression Pik3r2 0.19 0.1 7.5e-04 0.18 0.12 0.11 0.14 4.7e-05 9.7e-04 1.2e-03 2.7e-04
10 IL mRNA stability Pik3r2 0.24 0.16 1.1e-03 0.06 0.1 0.08 0.09 1.6e-02 2.8e-03 5.7e-03 4.4e-03
11 Adipose gene expression Pik3r2 0.27 0.09 0.0e+00 0.26 0.27 0.27 0.28 1.5e-28 2.4e-30 1.8e-30 1.5e-30
12 NAcc mRNA stability Pik3r2 0.04 0.02 1.2e-08 0.06 0.06 0.06 0.06 9.3e-10 6.5e-10 1.6e-09 4.8e-10
13 Brain isoform ratio XM_063275283.1 0.03 0.02 3.1e-03 0.02 0.02 0.02 0.01 4.1e-03 7.1e-03 9.0e-03 1.5e-02
14 Brain isoform ratio XM_039094436.2 0.03 0.02 2.2e-03 0.02 0.02 0.02 0.01 8.2e-03 2.6e-03 1.0e-02 3.7e-02
15 IC gene expression Pik3r2 0.12 0.07 2.1e-04 0.03 0.06 0.03 0.05 2.1e-02 1.1e-03 2.3e-02 4.2e-03
16 PL gene expression Pik3r2 0.08 0.05 1.2e-07 0.05 0.04 0.06 0.04 6.5e-06 2.2e-05 5.6e-07 7.4e-05
17 OFC mRNA stability Pik3r2 0.19 0.1 2.9e-04 0.1 0.1 0.11 0.09 2.6e-03 2.1e-03 1.2e-03 3.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.30.62.40.71.40.80.70.6-0.7-0.50.4-0.50.1-0.60.1-1.5-0.6-0.3-0.4-1.2
Area under the delay curve0.10.10.5-0.5-0.3-0.3-0.2-0.40.30.3-0.00.40.0-0.10.30.1-0.1-0.2-0.60.7
BMI with tail1.13.77.12.42.72.12.62.3-2.1-2.01.7-2.22.3-1.91.4-1.4-1.4-1.4-0.20.9
BMI without tail2.47.412.02.93.42.83.53.0-2.8-2.82.7-2.73.3-3.02.5-1.6-2.4-2.4-1.52.0
Body weight3.716.029.44.75.44.45.04.7-4.3-4.23.8-4.54.3-4.33.4-3.4-3.4-3.1-1.41.1
Weight adjusted by age1.62.43.91.81.91.61.91.7-1.6-2.01.5-1.71.7-1.81.4-0.9-1.4-1.3-0.80.8
Bone surface0.10.21.10.51.00.40.40.3-0.4-0.20.0-0.2-0.1-0.1-0.4-0.70.00.20.5-1.1
Bone volume0.50.82.81.11.71.11.10.9-1.0-0.90.7-0.80.6-0.90.4-1.4-0.7-0.5-0.1-0.5
Breakpoint value in progressive ratio session0.10.21.0-0.10.2-0.50.00.00.20.0-0.30.0-0.20.2-0.30.40.50.51.0-0.6
Number of licking bursts0.10.10.3-0.3-0.5-0.3-0.4-0.60.40.4-0.20.1-0.30.5-0.1-0.00.20.2-0.1-0.2
Context. condit. distance diff. score0.10.10.20.3-0.20.4-0.10.3-0.3-0.10.3-0.2-0.2-0.10.3-0.4-0.20.2-0.4-0.4
Locomotion velocity, session 11.11.25.4-0.4-0.4-0.7-0.3-0.70.70.6-1.00.4-0.50.7-1.21.51.51.62.3-1.3
Locomotion distance, session 12.73.46.8-1.5-1.4-1.6-1.6-1.51.61.7-2.01.4-1.81.7-2.11.82.22.32.6-2.1
Locomotion velocity, session 20.70.82.20.71.20.81.5-0.0-0.4-1.20.8-1.11.4-1.30.90.2-0.6-0.5-0.10.5
Locomotion distance, session 23.24.56.7-2.1-1.7-2.1-1.8-2.12.22.0-2.31.9-2.01.9-2.41.82.42.42.6-2.1
Locomotion velocity, session 30.40.40.8-0.7-0.9-0.6-0.5-0.80.80.6-0.70.5-0.60.5-0.70.50.70.90.5-0.8
Locomotion distance, session 30.80.92.7-0.6-0.7-0.7-0.9-0.40.60.9-1.00.5-1.21.0-1.20.31.01.11.1-1.7
Stereotopy head waving bouts, day 30.60.62.5-0.7-1.0-0.5-0.9-0.70.60.6-0.60.7-1.10.6-0.6-0.40.51.00.3-1.6
Stereotopy head waving duration, day 30.10.10.6-0.2-0.5-0.0-0.3-0.50.30.0-0.10.3-0.50.1-0.0-0.60.10.5-0.0-0.8
Locomotion velocity, session 70.91.01.7-1.0-1.3-1.1-1.1-0.81.21.0-1.00.8-0.91.2-0.91.21.11.01.0-0.1
Locomotion distance, session 71.11.42.3-1.3-1.4-1.3-1.5-0.91.51.4-1.21.2-1.21.5-1.11.01.10.80.6-0.2
Stereotopy head waving bouts, day 70.20.21.90.10.30.20.2-0.30.0-0.2-0.0-0.2-0.2-0.3-0.0-0.30.10.60.6-1.4
Stereotopy head waving duration, day 70.30.40.90.60.80.80.90.2-0.6-0.80.6-0.80.5-1.00.5-0.6-0.5-0.0-0.1-0.7
Locomotion velocity, session 81.61.94.1-1.2-1.5-1.1-1.1-1.11.31.2-1.41.0-1.21.0-1.41.51.62.01.8-1.3
Locomotion distance, session 81.11.63.4-0.9-1.0-1.0-1.1-0.81.11.1-1.31.0-1.31.1-1.41.21.51.81.8-1.6
Degree of sensitization distance0.20.21.0-0.5-0.7-0.5-0.4-0.60.70.4-0.20.6-0.10.30.00.60.1-0.1-0.51.0
Degree of sensitization stereotypy0.20.20.90.60.70.60.50.2-0.5-0.50.3-0.60.1-0.50.2-0.5-0.10.20.6-1.0
Conditioned locomotion0.10.10.60.3-0.10.2-0.30.8-0.50.20.1-0.0-0.30.1-0.2-0.4-0.0-0.10.0-0.3
Cocaine response after cond. corrected0.70.84.30.6-0.10.70.10.4-0.8-0.50.9-0.60.2-0.60.9-1.3-1.2-1.2-2.10.7
Cocaine response after cond. not corrected0.20.21.9-0.1-0.60.0-0.3-0.1-0.10.10.30.0-0.2-0.00.3-0.4-0.5-0.5-1.40.6
Cocaine response before conditioning1.72.14.4-1.5-1.0-1.6-0.8-1.41.81.1-1.51.6-0.81.2-1.32.11.71.61.9-0.4
Saline control response0.30.51.2-0.5-0.2-0.6-0.3-0.60.50.6-0.70.4-0.50.5-0.80.50.81.01.1-1.1
Bone: connectivity density0.20.31.20.61.10.60.40.4-0.6-0.30.2-0.30.0-0.4-0.1-0.9-0.2-0.20.1-0.8
Bone: cortical apparent density0.30.41.8-0.9-0.0-0.7-0.1-0.90.80.6-0.60.50.10.2-0.41.30.50.20.2-0.0
Bone: cortical area4.97.513.03.03.63.03.13.0-2.9-3.02.7-2.82.7-2.72.5-3.2-2.5-2.2-1.21.2
Bone: cortical porosity0.40.42.8-0.3-0.2-0.5-0.3-0.30.30.5-0.70.2-0.40.6-0.80.50.90.81.7-0.3
Bone: cortical porosity0.40.42.9-0.2-0.2-0.4-0.3-0.10.20.5-0.60.2-0.40.6-0.90.40.90.81.7-0.4
Bone: cortical thickness3.05.010.12.63.02.62.42.6-2.6-2.32.1-2.31.8-2.11.8-3.2-1.9-1.5-0.6-0.0
Bone: cortical thickness2.02.38.01.81.61.91.02.1-2.0-1.31.5-1.60.5-1.21.1-2.8-1.3-0.8-0.6-0.6
Bone: cortical tissue density0.30.52.1-1.0-0.2-0.8-0.2-1.00.90.7-0.70.6-0.00.3-0.51.50.60.30.2-0.0
Condit. Reinf. active minus inactive responses0.30.42.00.60.70.60.30.8-0.7-0.50.3-0.5-0.1-0.40.2-1.4-0.10.20.6-0.9
Condit. Reinf. active-inactive response ratio0.30.42.60.50.60.50.20.7-0.6-0.50.5-0.5-0.1-0.30.6-1.6-0.5-0.3-0.2-0.5
Condit. Reinf. active responses0.40.51.30.80.80.70.51.0-0.8-0.60.4-0.80.1-0.60.3-1.1-0.20.20.6-0.7
Condit. Reinf. inactive responses0.20.30.50.70.60.60.70.7-0.6-0.50.4-0.60.6-0.60.20.2-0.2-0.20.20.5
Incentive salience index mean0.40.41.70.61.00.50.60.7-0.5-0.50.1-0.60.1-0.5-0.0-0.80.20.51.2-1.3
Condit. Reinf. lever presses0.40.63.60.41.10.30.80.4-0.0-0.5-0.2-0.50.2-0.4-0.40.00.60.91.9-1.6
Condit. Reinf. active minus inactive responses0.30.40.7-0.5-0.4-0.7-0.5-0.60.70.7-0.70.5-0.60.7-0.70.50.80.80.9-0.8
Condit. Reinf. active-inactive response ratio0.20.30.50.60.60.50.60.6-0.5-0.60.5-0.70.4-0.40.5-0.7-0.4-0.3-0.10.1
Condit. Reinf. active responses1.31.82.7-1.4-1.3-1.5-1.1-1.61.51.4-1.41.3-1.01.3-1.31.61.51.41.3-0.9
Condit. Reinf. inactive responses2.22.95.8-1.9-1.9-1.9-1.5-2.21.81.8-1.71.8-1.21.5-1.52.41.71.41.1-0.4
Condit. Reinf. lever presses0.10.10.6-0.00.2-0.10.5-0.2-0.1-0.20.2-0.10.6-0.30.30.7-0.1-0.2-0.30.6
Condit. Reinf. lever reinforcers received0.40.51.3-0.8-0.6-0.9-0.4-1.00.80.7-0.70.6-0.30.6-0.61.10.70.60.5-0.2
Conditioned reinforcement - actives1.42.43.91.81.42.01.51.7-1.7-1.61.6-1.61.5-1.51.4-1.2-1.6-1.6-1.21.2
Conditioned reinforcement - inactives7.511.014.63.43.33.63.33.5-3.8-3.53.3-3.53.0-3.33.2-3.7-3.4-3.3-2.52.3
Conditioned locomotion2.12.74.52.01.32.11.51.6-1.7-1.61.8-1.41.7-1.61.7-1.2-1.8-1.8-1.71.4
Patch foraging indifference point 0 sec2.24.05.42.32.22.22.32.3-2.3-2.02.1-2.22.1-2.22.0-1.6-1.8-1.5-1.31.2
Patch foraging indifference point AUC0.10.20.8-0.50.0-0.40.1-0.60.60.2-0.30.20.3-0.0-0.10.90.1-0.1-0.60.1
Delay disc. indifference point, 0s delay2.22.43.9-2.0-1.9-1.8-1.6-1.81.71.6-1.71.7-1.31.5-1.31.41.41.30.7-0.7
Delay disc. indifference point, 16s delay0.50.61.2-0.9-1.0-0.9-0.7-0.90.81.0-0.40.8-0.30.5-0.21.10.2-0.1-0.90.9
Delay disc. indifference point, 2s delay0.80.81.8-1.3-0.7-1.0-0.9-1.11.00.8-1.01.0-0.90.6-0.60.41.01.01.1-0.6
Delay disc. indifference point, 24s delay0.30.31.30.10.10.40.50.3-0.3-0.40.4-0.30.8-0.60.70.0-0.6-0.7-1.01.1
Delay disc. indifference point, 4s delay0.10.10.4-0.5-0.0-0.3-0.1-0.50.60.2-0.30.6-0.00.0-0.10.20.40.40.5-0.2
Delay disc. indifference point, 8s delay0.50.62.10.20.30.20.40.4-0.4-0.50.7-0.40.7-0.71.1-0.5-0.9-1.0-1.41.3
Indifference point function ln k0.61.02.41.50.81.30.71.5-1.5-1.01.2-0.90.7-0.70.9-1.0-0.8-0.8-0.00.8
Indifference point function log k0.61.02.41.50.81.30.71.5-1.5-1.01.2-0.90.7-0.70.9-1.0-0.8-0.8-0.00.8
Patch foraging total patch changes 0 sec3.46.48.22.82.72.72.92.8-2.8-2.62.6-2.82.7-2.72.5-2.0-2.3-2.1-1.71.7
Patch foraging total patch changes 12 sec0.81.01.90.80.90.91.30.9-0.9-0.91.0-1.11.3-1.11.1-0.5-1.0-0.9-1.40.9
Patch foraging total patch changes 18 sec0.00.00.3-0.0-0.1-0.10.1-0.2-0.10.3-0.1-0.10.1-0.1-0.20.10.0-0.0-0.5-0.2
Patch foraging total patch changes 24 sec0.30.51.21.00.70.90.61.1-0.9-0.60.7-0.80.4-0.70.5-1.0-0.5-0.4-0.4-0.2
Patch foraging total patch changes 6 sec1.32.03.41.41.51.51.81.5-1.3-1.51.5-1.51.8-1.81.6-0.7-1.2-1.0-1.30.8
Patch foraging time to switch 0 sec1.42.85.4-2.0-1.5-1.9-1.4-2.31.91.7-1.91.6-1.31.4-1.71.91.61.61.0-1.3
Patch foraging water rate 0 sec0.91.92.91.51.61.61.61.7-1.4-1.61.5-1.41.5-1.51.4-1.3-1.1-1.1-0.41.0
Patch foraging water rate 12 sec0.30.71.81.20.91.00.71.3-1.1-0.70.9-0.80.7-0.60.6-0.9-0.6-0.70.20.7
Patch foraging water rate 18 sec0.20.32.1-0.1-0.1-0.3-0.40.10.20.4-0.40.5-0.40.6-0.60.20.80.61.5-0.1
Patch foraging water rate 24 sec0.20.21.70.50.80.50.40.7-0.3-0.40.2-0.10.2-0.2-0.0-0.30.20.21.30.1
Patch foraging water rate 6 sec1.72.55.62.01.41.91.42.4-2.0-1.51.7-1.41.4-1.31.4-1.5-1.4-1.4-0.51.4
Seeking ratio, delayed vs. immediate footshock1.01.22.8-1.1-1.2-1.2-0.7-1.21.21.3-1.21.0-0.51.0-1.11.71.11.10.8-0.6
Distance traveled before self-admin0.50.61.50.71.00.61.20.9-0.6-1.10.7-0.81.1-1.00.8-0.1-0.7-0.5-0.30.5
Distance traveled after self-admin0.70.91.91.11.20.61.41.1-1.1-1.30.8-1.31.1-1.00.6-0.7-0.7-0.5-0.00.1
Extensor digitorum longus weight0.20.71.81.01.10.91.40.6-0.8-1.00.8-1.01.1-1.00.7-0.3-0.7-0.4-0.4-0.1
Bone: elastic displacement0.60.71.8-0.8-0.5-0.7-0.6-0.80.90.6-0.91.0-0.70.5-0.80.41.01.11.3-0.9
Bone: elastic work1.31.72.91.31.71.41.61.3-1.2-1.51.2-1.11.4-1.41.3-1.5-1.2-1.0-0.50.8
Bone: endosteal estimation0.30.63.50.50.40.40.50.4-0.3-0.70.7-0.30.8-0.50.80.1-0.7-1.0-0.91.9
Bone: endosteal perimeter1.22.53.41.81.41.61.41.6-1.6-1.81.7-1.51.5-1.31.6-1.6-1.5-1.6-1.01.9
Epididymis fat weight0.41.54.71.02.21.01.91.0-0.7-1.21.0-1.01.9-1.41.20.3-0.8-1.10.01.1
Delta time in closed arm before/after self-admin0.40.31.30.30.30.50.3-0.0-0.1-0.40.7-0.00.5-0.50.80.5-0.6-0.7-1.01.2
Delta time in open arm before/after self-admin1.11.12.3-1.3-0.7-1.5-0.8-1.01.20.9-1.11.1-0.71.0-1.01.41.00.90.7-0.6
Diff in mean of infusions in LGA sessions1.01.32.91.01.20.81.61.1-0.7-1.11.1-1.01.7-1.41.30.3-0.9-0.9-0.71.5
Delay discount exponential model param0.10.10.50.2-0.0-0.0-0.00.1-0.00.0-0.2-0.1-0.20.3-0.50.30.30.40.6-0.7
Extinction: sum of active levers before priming1.31.42.2-1.5-0.4-1.4-0.8-1.11.31.1-1.41.0-0.91.1-1.11.31.41.31.5-1.2
Active lever presses in extinction session 60.30.31.1-0.6-0.4-0.6-0.3-0.60.60.4-0.50.5-0.20.4-0.41.00.40.40.4-0.0
Bone: final force6.810.815.63.63.93.53.73.3-3.4-3.63.4-3.53.4-3.33.3-2.9-3.1-3.0-2.12.3
Bone: final moment6.710.714.53.63.83.53.63.4-3.5-3.63.4-3.43.3-3.23.3-2.8-3.2-3.1-2.22.4
Food consumed during 24 hour testing period0.91.22.8-0.9-0.5-1.0-0.8-0.41.01.0-1.30.9-1.11.0-1.40.71.31.41.5-1.7
Glucose1.21.92.91.31.71.41.71.5-1.0-1.41.3-1.31.7-1.61.4-1.2-1.1-1.2-0.61.3
Heart weight1.21.86.11.91.41.61.11.9-1.7-1.31.3-1.50.5-1.11.0-2.5-1.0-0.40.0-0.6
Delay discount hyperbolic model param0.10.10.30.2-0.00.0-0.00.2-0.1-0.0-0.2-0.2-0.10.3-0.40.30.20.20.4-0.5
Intermittent access intake day 1-15 change0.10.21.30.50.60.40.20.3-0.6-0.40.3-0.20.0-0.20.1-1.2-0.2-0.20.1-0.3
Intermittent access intake escalation0.10.11.00.20.30.1-0.10.0-0.3-0.1-0.00.1-0.30.1-0.2-1.00.00.10.3-0.5
Intermittent access intake escalation 20.20.30.70.40.80.30.70.4-0.6-0.60.4-0.60.7-0.50.4-0.4-0.5-0.6-0.30.3
Intermitt. access day 1 inactive lever presses0.10.40.70.60.50.80.60.8-0.7-0.70.6-0.70.5-0.60.6-0.8-0.6-0.5-0.60.2
Intermitt. access day 15 inactive lever presses0.10.21.40.6-0.30.4-0.10.4-0.4-0.30.1-0.3-0.30.2-0.3-1.2-0.1-0.0-0.0-0.3
Intermitt. access escalation Index0.40.61.1-0.8-1.0-0.8-0.9-0.60.71.1-0.81.0-0.80.8-0.70.40.60.50.2-0.4
Intermittent access day 1 total infusions1.42.23.81.80.91.71.21.6-1.5-1.31.7-1.31.4-1.31.6-0.9-1.5-1.6-1.61.9
Intermittent access day 15 total infusions0.40.62.11.00.60.60.40.9-1.1-0.60.8-0.60.3-0.50.6-1.4-0.7-0.8-0.60.6
Intermittent access terminal intake (last 3 days)0.40.61.41.00.60.60.40.8-1.1-0.50.8-0.70.4-0.40.6-1.2-0.8-0.9-0.70.8
Intermittent access total infusions1.92.33.01.61.31.31.31.6-1.6-1.41.7-1.31.3-1.41.7-1.3-1.6-1.7-1.61.7
Intermittent access day 1 locomotion2.63.35.02.11.62.21.71.9-1.8-1.82.1-1.51.8-1.82.0-0.9-1.8-1.9-1.62.0
Intermittent access day 15 total locomotion0.20.30.80.90.60.70.40.6-0.8-0.60.7-0.40.3-0.40.5-0.6-0.5-0.7-0.40.3
Intermittent access total locomotion2.53.04.11.91.72.01.71.7-1.7-1.72.0-1.51.7-1.72.0-1.0-1.7-1.8-1.61.8
Intermittent access standard deviation0.20.40.60.70.50.50.60.6-0.8-0.70.6-0.70.7-0.50.5-0.7-0.7-0.8-0.70.6
Left kidney weight0.31.23.11.21.71.11.81.3-1.0-1.10.9-1.11.5-1.40.8-0.2-0.7-0.5-0.00.1
Right kidney weight0.83.58.61.82.91.82.82.0-1.4-2.01.5-1.92.7-2.31.6-0.3-1.3-1.4-0.50.8
Cocaine induced anxiety1.42.03.51.91.21.61.61.4-1.3-1.81.6-1.41.5-1.51.5-0.8-1.2-1.1-0.91.0
Post-drug Anxiety0.00.00.20.40.00.10.30.0-0.2-0.50.2-0.20.4-0.20.1-0.1-0.1-0.1-0.00.1
Baseline Anxiety3.33.86.4-2.5-1.9-2.5-1.9-2.11.92.1-2.21.9-1.82.0-2.01.31.81.71.5-1.3
Tail length0.62.44.91.42.21.62.11.2-1.2-1.71.5-1.52.0-2.11.6-0.6-1.4-1.3-1.00.8
Length with tail1.45.912.92.53.62.63.12.5-2.4-2.72.2-2.72.7-3.02.2-1.8-2.1-1.9-1.10.3
Length without tail1.13.77.52.22.72.22.12.3-2.1-2.01.6-2.31.5-1.91.5-2.4-1.6-1.3-0.6-0.6
Times rat made contact with spout0.40.40.8-0.6-0.4-0.7-0.6-0.30.70.7-0.80.6-0.60.9-0.80.50.60.50.6-0.7
Lifetime Intake3.03.74.92.21.62.11.72.2-2.2-1.82.1-1.81.7-1.82.0-1.9-2.0-2.0-1.71.8
Liver weight, left0.91.62.8-1.4-0.4-1.3-0.7-1.41.51.2-1.41.2-0.81.0-1.21.51.41.31.7-1.3
Liver weight, right0.71.33.90.92.00.81.81.0-0.7-1.10.8-1.21.8-1.31.10.3-0.9-1.1-0.40.5
Locomotor activity0.61.04.1-0.90.4-0.7-0.1-1.21.10.4-1.00.9-0.40.4-0.80.51.11.22.0-1.5
Locomotor testing distance0.61.12.3-1.1-0.4-1.0-0.7-1.31.20.9-1.11.2-0.90.9-1.00.51.11.21.5-1.4
Locomotor testing rearing0.81.63.0-1.2-0.5-1.2-0.8-1.31.31.1-1.41.1-1.01.0-1.41.41.51.51.7-1.5
Locomotion in novel chamber0.10.10.4-0.30.5-0.10.20.00.2-0.1-0.20.10.1-0.10.00.30.10.10.2-0.7
Locomotion in novel chamber post-restriction0.30.53.1-0.30.4-0.2-0.4-0.30.20.2-0.60.2-0.80.5-0.8-0.30.70.81.4-1.8
Fecal boli incidents, locomotor time 10.10.20.5-0.4-0.4-0.6-0.4-0.70.60.2-0.30.6-0.10.3-0.10.40.2-0.1-0.10.6
Change in fecal boli incidents, locomotor task0.20.20.5-0.6-0.7-0.5-0.4-0.30.10.4-0.50.3-0.30.4-0.40.60.40.40.20.1
Time >=10cm from walls, locomotor time 10.10.11.00.30.10.00.10.00.20.40.40.20.4-0.10.10.6-0.1-0.4-0.51.0
Bouts of movement, locomotor time 10.70.72.4-1.0-0.5-0.8-0.5-1.01.10.8-1.00.6-0.50.8-1.01.50.90.60.6-0.8
Total resting periods, locomotor time 11.21.33.1-1.2-0.8-1.1-0.9-1.41.41.2-1.31.0-0.81.1-1.41.81.20.90.9-1.0
Rest time, locomotor task time 10.00.00.30.0-0.5-0.1-0.1-0.40.2-0.0-0.10.10.00.1-0.10.2-0.1-0.2-0.30.2
Distance moved, locomotor task time 10.00.00.2-0.2-0.1-0.2-0.10.4-0.20.20.00.1-0.00.10.00.10.00.0-0.20.4
Vertical activity count, locomotor time 10.10.21.0-1.00.3-0.60.1-0.10.40.3-0.50.40.00.2-0.20.50.40.40.5-0.3
Time >=10cm from walls, locomotor time 20.40.61.6-0.5-1.2-0.8-1.1-0.90.71.0-0.61.2-0.90.9-0.60.10.50.50.1-0.1
Bouts of movement, locomotor time 20.20.31.9-0.4-0.3-0.3-0.3-0.70.60.2-0.50.2-0.60.3-0.70.30.60.80.6-1.4
Total resting periods, locomotor time 20.10.21.5-0.1-0.2-0.1-0.2-0.50.40.0-0.3-0.0-0.50.1-0.60.10.40.60.4-1.2
Rest time, locomotor task time 20.30.41.00.30.70.50.80.3-0.5-0.90.5-1.00.7-0.90.6-0.0-0.7-0.6-0.40.3
Distance moved, locomotor task time 20.10.10.3-0.1-0.6-0.2-0.50.1-0.10.3-0.00.5-0.30.50.0-0.2-0.0-0.1-0.40.3
Vertical activity count, locomotor time 20.10.11.0-0.2-0.1-0.2-0.2-0.20.10.2-0.10.6-0.20.20.1-1.0-0.00.2-0.0-0.1
Light reinforcement 10.10.21.0-0.00.20.10.3-0.1-0.0-0.40.3-0.30.6-0.40.50.4-0.3-0.6-0.61.0
Light reinforcement 20.81.25.00.30.40.50.80.3-0.7-0.71.0-0.91.2-1.01.40.3-1.3-1.5-2.21.7
Bone: marrow area0.20.43.00.40.30.30.40.3-0.1-0.60.6-0.20.7-0.40.70.2-0.6-0.9-0.81.7
Bone: maximum diameter2.75.07.52.62.42.52.22.5-2.5-2.42.3-2.22.0-2.22.2-2.7-2.1-1.9-1.31.6
Bone: maximum force5.19.015.83.44.03.33.63.2-3.1-3.42.9-3.33.1-2.92.8-2.7-2.7-2.5-1.21.8
Bone: maximum moment4.78.313.53.23.73.13.33.1-3.0-3.32.9-3.12.9-2.82.8-2.5-2.6-2.5-1.31.9
Mean time between licks in bursts1.33.15.21.72.11.72.21.4-1.5-2.31.8-2.02.1-1.92.0-1.1-1.6-1.7-0.91.6
Mean num. licks in bursts0.00.10.40.10.3-0.0-0.00.6-0.2-0.0-0.20.2-0.20.1-0.4-0.10.10.00.3-0.4
Cd content in liver2.12.45.71.51.51.61.01.6-1.9-1.51.6-1.70.8-1.21.5-2.4-1.7-1.7-1.51.0
Co content in liver0.00.00.4-0.00.1-0.00.0-0.30.1-0.3-0.1-0.2-0.10.10.0-0.0-0.00.1-0.0-0.6
Cu content in liver2.32.75.6-1.2-1.3-1.2-1.7-0.91.11.4-1.71.6-2.01.6-1.90.81.92.12.4-2.3
Fe content in liver0.81.03.2-1.4-0.9-1.3-0.9-1.81.31.0-1.11.0-0.81.0-0.70.80.80.60.3-0.2
K content in liver1.51.53.4-1.3-1.8-1.3-1.6-1.11.11.1-1.21.2-1.41.4-1.11.21.11.10.7-0.4
Mg content in liver0.10.10.30.0-0.50.0-0.40.3-0.20.1-0.10.1-0.50.3-0.20.10.20.30.3-0.3
Mn content in liver0.10.10.40.40.00.30.00.4-0.4-0.30.2-0.4-0.1-0.10.1-0.20.10.20.6-0.1
Na content in liver3.73.94.9-2.1-1.9-2.1-1.9-1.72.12.0-2.12.2-1.81.9-2.01.92.12.12.0-1.6
Rb content in liver3.03.57.11.91.11.91.12.2-2.2-1.82.0-1.91.1-1.51.9-2.7-2.1-1.9-2.31.2
Se content in liver0.40.41.2-0.5-0.6-0.4-0.7-0.30.40.6-0.60.5-0.80.7-0.60.00.80.91.1-0.7
Sr content in liver0.40.31.0-0.8-0.3-0.7-0.3-0.90.80.5-0.50.5-0.10.4-0.61.00.50.20.30.2
Zn content in liver0.10.10.4-0.4-0.2-0.3-0.1-0.10.20.2-0.40.3-0.10.1-0.50.40.40.40.70.1
Bone: minimum diameter1.62.95.61.72.41.72.21.4-1.5-2.01.6-1.62.1-1.81.6-1.4-1.5-1.6-0.91.5
Time in familiar zone, hab. session 10.10.10.30.20.50.10.50.4-0.2-0.30.2-0.30.5-0.50.20.0-0.2-0.3-0.10.5
Time in novel zone, hab. session 10.10.10.60.1-0.10.2-0.2-0.1-0.1-0.00.10.0-0.30.10.1-0.8-0.10.0-0.0-0.2
Total zone transitions, hab. session 10.81.22.6-1.0-0.7-1.1-0.8-1.21.01.1-1.10.9-0.80.8-1.11.61.31.21.5-0.5
Total locomotion distance, hab. session 12.33.25.8-1.8-1.2-1.9-1.6-1.91.91.7-2.01.8-1.61.6-1.91.92.11.92.4-1.2
Locomotion velocity, hab. session 12.33.25.7-1.8-1.2-1.9-1.5-2.01.81.7-1.91.7-1.51.6-1.82.32.11.92.4-1.0
Time in familiar zone, hab. session 20.10.10.40.40.30.30.30.6-0.5-0.30.3-0.10.4-0.30.3-0.2-0.2-0.3-0.30.4
Time in novel zone, hab. session 20.00.00.4-0.20.0-0.1-0.1-0.60.3-0.0-0.0-0.1-0.1-0.00.1-0.0-0.2-0.3-0.30.1
Total zone transitions, hab. session 20.20.20.7-0.1-0.4-0.3-0.5-0.10.10.4-0.40.0-0.60.4-0.50.60.50.50.8-0.4
Total locomotion distance, hab. session 20.60.83.1-0.4-0.5-0.6-0.8-0.40.50.7-0.90.4-1.10.8-1.00.51.11.21.8-1.3
Locomotion velocity, hab. session 20.91.13.7-0.7-0.6-0.8-0.9-0.60.70.9-1.10.6-1.20.9-1.20.81.31.41.9-1.3
Novel to familiar place preference ratio0.30.31.2-0.00.50.20.4-0.5-0.0-0.50.5-0.10.6-0.60.7-0.1-0.7-1.0-1.10.9
Novelty place preference0.30.30.9-0.10.30.10.2-0.60.0-0.40.4-0.00.5-0.50.7-0.1-0.6-0.9-1.00.9
Time in novel zone, NPP test0.20.20.8-0.40.0-0.2-0.1-0.90.4-0.10.10.30.2-0.20.40.2-0.3-0.6-0.70.8
Total zone transitions, NPP test1.11.63.4-1.0-1.0-1.1-1.2-0.80.91.2-1.31.1-1.41.3-1.51.41.51.51.8-1.3
Total locomotion distance, NPP test2.53.47.0-1.5-1.4-1.6-1.8-1.11.51.8-1.91.8-2.01.8-2.11.52.22.32.6-2.0
Locomotion velocity, NPP test2.33.26.0-1.5-1.5-1.6-1.7-1.11.41.8-1.91.7-1.91.8-2.01.72.12.22.5-1.8
Intraocular pressure1.62.33.61.31.41.51.41.0-1.3-1.71.6-1.41.3-1.61.7-1.9-1.8-1.6-1.71.0
Delta distance traveled before/after self-admin0.30.31.00.31.00.10.90.7-0.6-0.80.4-0.80.8-0.60.4-0.3-0.4-0.50.00.2
Delta ambulatory time before/after self-admin0.10.10.40.10.50.00.40.4-0.4-0.40.1-0.60.2-0.20.1-0.7-0.2-0.20.10.1
Parametrial fat weight3.78.612.52.82.82.73.22.8-2.7-3.03.1-2.93.5-3.03.2-0.9-3.1-3.3-3.03.1
Pavlov. Cond. lever latency0.60.74.10.4-0.40.4-0.20.4-0.7-0.30.8-0.10.3-0.20.9-0.7-0.9-1.3-1.62.0
Pavlov. Cond. magazine entry latency0.10.10.40.30.60.30.60.4-0.4-0.20.3-0.50.6-0.50.20.2-0.3-0.3-0.40.0
Pavlov. Cond. change in total contacts0.50.51.60.61.30.71.20.5-0.4-0.80.5-1.00.9-1.00.5-0.3-0.5-0.2-0.0-0.5
Pavlov. Cond. index score0.30.41.4-0.50.3-0.50.2-0.40.60.4-0.60.1-0.10.1-0.71.10.70.81.0-1.2
Pavlov. Cond. latency score0.60.72.5-0.60.1-0.60.0-0.70.80.6-0.90.2-0.30.3-0.91.21.01.21.3-1.6
Pavlov. Cond. lever contacts0.40.42.3-0.30.6-0.30.4-0.40.60.1-0.6-0.10.1-0.0-0.60.70.70.91.2-1.5
Pavlov. Cond. magazine entry number0.20.20.6-0.4-0.7-0.4-0.8-0.70.40.3-0.40.6-0.70.5-0.3-0.50.30.30.3-0.1
Pavlov. Cond. intertrial magazine entries0.50.62.90.1-0.30.1-0.70.4-0.10.2-0.30.1-1.20.7-0.5-1.50.40.91.0-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-0.30.3-0.30.2-0.30.50.3-0.5-0.00.00.1-0.60.90.60.70.8-1.0
Pavlov. Cond. response bias0.10.10.40.20.60.10.50.4-0.1-0.10.0-0.40.4-0.3-0.00.50.10.10.3-0.6
Pavlov. Cond. lever latency0.60.82.0-0.4-1.1-0.5-1.40.00.51.0-0.80.7-1.41.1-1.1-0.10.80.70.9-0.8
Pavlov. Cond. magazine entry latency0.40.51.20.51.00.51.10.3-0.4-0.70.7-0.81.0-0.90.7-0.1-0.7-0.6-1.10.1
Pavlov. Cond. change in total contacts0.40.71.80.61.00.61.30.2-0.6-1.00.8-1.01.3-1.01.0-0.2-0.8-0.6-0.80.4
Pavlov. Cond. index score0.91.22.60.81.30.81.60.3-0.8-1.31.1-1.11.6-1.41.3-0.3-1.1-0.9-1.30.7
Pavlov. Cond. latency score0.50.61.60.41.00.51.2-0.0-0.4-0.90.7-0.71.2-1.00.9-0.1-0.8-0.6-1.10.3
Pavlov. Cond. lever contacts0.40.61.50.40.90.51.2-0.0-0.4-0.90.7-0.61.2-1.01.00.1-0.7-0.5-0.80.6
Pavlov. Cond. magazine entry number1.31.63.5-0.9-1.6-1.0-1.9-0.70.91.4-1.21.3-1.81.5-1.40.31.31.11.4-0.8
Pavlov. Cond. intertrial magazine entries0.71.12.1-0.7-1.2-0.9-1.3-0.70.71.1-1.00.8-1.21.3-1.20.91.20.91.4-0.2
Pavlov. Cond. lever-magazine prob. diff.1.01.32.90.81.40.91.70.4-0.8-1.31.1-1.21.6-1.41.3-0.3-1.1-0.9-1.30.7
Pavlov. Cond. response bias0.81.12.40.71.30.81.60.4-0.8-1.21.0-1.01.6-1.21.2-0.0-0.9-0.9-0.90.9
Time in closed arm before self-admin5.36.79.53.02.32.53.03.0-2.9-3.12.6-2.92.8-2.82.5-2.3-2.4-2.0-1.61.3
Time in closed arm after self-admin6.36.88.42.82.02.72.62.4-2.6-2.72.9-2.42.7-2.72.9-1.8-2.8-2.6-2.72.4
Time in open arm before self-admin2.02.13.9-1.4-0.7-1.0-1.2-1.31.51.6-1.51.1-1.41.3-1.51.91.71.72.0-1.7
Time in open arm after self-admin4.54.98.6-2.1-1.2-1.9-1.8-2.12.22.1-2.42.1-2.22.1-2.51.82.52.62.9-2.8
Bone: periosteal estimation1.73.65.22.02.32.02.11.9-1.8-2.21.9-1.72.0-1.81.9-1.8-1.8-1.8-1.11.8
Bone: periosteal perimeter4.67.910.33.23.13.12.93.0-3.1-3.12.9-2.92.6-2.72.7-3.2-2.7-2.5-1.81.8
Bone: post-yield work0.10.10.5-0.1-0.1-0.2-0.4-0.20.20.1-0.30.3-0.50.5-0.30.00.30.20.7-0.1
Progressive ratio test 1 active lever presses2.93.66.32.51.92.51.92.3-2.0-1.92.2-2.01.8-1.91.9-1.3-1.6-1.5-1.11.4
Progressive ratio test 1 breakpoint2.73.35.82.41.82.41.82.2-1.9-1.72.1-1.91.7-1.81.8-1.3-1.6-1.4-1.01.3
Progressive ratio test 1 inactive lever presses1.31.83.21.61.31.61.51.8-1.5-1.41.4-1.41.4-1.41.2-1.1-1.2-1.1-0.70.9
Progressive ratio test 2 active lever presses1.31.52.01.41.01.21.01.3-1.4-1.01.4-1.11.1-1.21.4-1.0-1.3-1.4-1.31.4
Progressive ratio test 2 breakpoint1.01.11.61.20.81.00.91.0-1.2-0.81.2-0.91.0-1.01.2-0.8-1.1-1.2-1.21.3
Progressive ratio test 2 inactive lever presses1.32.25.32.01.21.61.21.9-1.9-1.51.5-1.71.0-1.21.1-2.3-1.4-1.2-0.90.6
Incentive Sensitization - Responses0.20.31.70.3-0.1-0.2-0.00.3-0.60.10.5-0.20.3-0.10.5-0.3-0.7-0.9-1.31.2
Incentive Sensitization - Breakpoint0.20.21.40.0-0.3-0.4-0.30.0-0.30.30.30.10.10.10.30.1-0.5-0.8-1.21.1
Sum of active levers in priming session hrs 5-64.44.16.1-2.3-1.8-2.0-2.4-2.22.02.2-2.22.1-2.52.3-2.00.41.91.81.6-1.8
Progressive ratio0.00.00.2-0.2-0.2-0.2-0.2-0.10.00.1-0.10.1-0.20.1-0.0-0.2-0.2-0.2-0.5-0.1
Food seeking constrained by brief footshock0.40.52.0-0.2-0.4-0.4-1.0-0.60.20.5-0.30.5-1.30.7-0.4-1.40.20.30.0-1.0
Seeking ratio, punishment vs. effort0.40.51.0-0.5-0.4-0.6-0.8-0.80.60.7-0.70.7-1.00.8-0.7-0.20.80.91.0-1.0
Retroperitoneal fat weight2.711.314.23.53.73.53.83.7-3.3-3.53.6-3.23.8-3.53.5-2.5-3.3-3.3-2.32.9
Reaction time number correct0.61.15.3-0.6-0.2-0.8-0.4-0.50.90.7-1.20.8-0.60.9-1.30.81.41.42.3-1.3
Reaction time mean minus median0.00.10.3-0.2-0.1-0.30.0-0.30.40.1-0.20.1-0.0-0.1-0.20.50.30.30.2-0.5
Reaction time mean minus median AUC0.00.10.20.40.00.20.10.5-0.3-0.20.2-0.40.0-0.20.1-0.20.10.10.2-0.3
Reaction time num false alarms0.91.22.11.11.11.31.01.1-1.1-1.31.1-1.30.8-1.21.1-1.4-1.1-0.9-0.90.2
Reaction time num false alarms AUC0.60.91.90.80.91.10.80.7-0.9-1.20.9-1.10.7-1.11.1-1.4-1.0-0.8-0.90.3
Reaction time trials correct on left0.61.15.3-0.6-0.2-0.8-0.4-0.50.90.7-1.20.8-0.60.9-1.30.81.41.42.3-1.3
Reaction time trials on left0.61.15.1-0.5-0.1-0.7-0.3-0.40.90.7-1.10.7-0.60.8-1.30.81.41.32.3-1.2
Reaction time mean1.21.93.91.11.11.21.31.0-1.0-1.41.5-1.31.5-1.51.6-0.7-1.5-1.7-2.01.6
Reaction time mean AUC0.60.92.40.60.50.60.80.4-0.5-0.91.0-0.81.1-1.01.1-0.2-1.0-1.3-1.61.4
Median of all reaction times1.82.55.81.21.01.31.31.1-1.2-1.51.7-1.41.6-1.51.9-1.0-1.9-2.1-2.42.1
Reaction time omissions0.91.22.41.01.51.01.50.7-0.8-1.40.9-1.51.5-1.41.0-0.5-1.0-1.1-0.70.6
Reaction time false alarm rate1.41.93.21.11.11.51.01.1-1.4-1.51.5-1.50.9-1.51.6-1.7-1.6-1.4-1.80.7
Reaction time premature initiation rate0.50.71.9-0.3-0.5-0.6-0.7-0.10.40.8-0.70.6-1.00.8-1.00.51.11.31.4-1.3
Reaction time premature initiations0.71.24.9-0.4-0.3-0.7-0.6-0.20.60.8-1.00.8-1.00.9-1.30.81.51.62.2-1.6
Std. dev. reaction times0.30.51.00.50.90.60.90.5-0.4-0.80.6-0.80.9-1.00.70.0-0.6-0.7-0.60.2
Reaction time trials completed0.61.15.1-0.5-0.1-0.7-0.3-0.40.90.7-1.10.7-0.60.8-1.30.81.41.32.3-1.2
Reaction time trials AUC0.40.74.1-0.30.1-0.6-0.2-0.30.70.5-0.90.6-0.40.6-1.10.71.21.12.0-1.0
Run reversals in cocaine runway, females3.73.75.52.11.92.12.02.2-2.3-2.01.9-2.31.7-1.81.7-2.1-1.9-1.8-1.31.2
Run reversals in cocaine runway, males1.51.62.0-1.1-1.2-1.2-1.2-0.91.11.1-1.31.1-1.31.4-1.41.21.41.31.3-1.4
Latency to leave start box in cocaine runway0.00.00.50.40.0-0.00.1-0.1-0.1-0.00.1-0.10.10.0-0.20.70.0-0.10.10.1
Latency to leave start box in cocaine runway, F0.10.20.50.70.60.40.50.3-0.4-0.50.3-0.60.4-0.40.20.2-0.2-0.30.4-0.0
Latency to leave start box in cocaine runway, M0.30.20.7-0.2-0.8-0.6-0.6-0.50.40.5-0.20.5-0.30.5-0.20.80.2-0.0-0.60.5
Std. dev. time between licks in bursts1.72.33.71.51.91.51.81.2-1.3-1.91.5-1.81.7-1.51.6-1.2-1.5-1.5-1.01.3
Total sessions with >9 infusions5.16.112.53.02.43.52.43.0-2.8-2.32.7-2.62.2-2.42.4-2.1-2.3-2.2-1.61.8
Short access day 1 total inactive lever presses2.22.95.52.11.12.01.31.9-2.0-1.31.7-1.61.3-1.41.4-2.4-1.9-1.9-1.91.3
Short access day 10 total inactive lever presses0.10.20.8-0.3-0.9-0.3-0.3-0.20.40.4-0.40.3-0.30.4-0.50.20.40.60.0-0.3
Short access day 1 total infusions3.64.87.72.42.32.82.22.6-2.5-2.02.2-2.32.0-2.12.0-2.3-2.2-2.0-1.31.5
Short access day 10 total infusions1.21.53.81.80.91.90.91.6-1.5-1.21.3-1.20.8-1.00.9-1.5-1.1-1.1-0.60.8
Short access total infusions2.83.66.82.31.62.61.72.3-2.2-1.72.0-1.91.6-1.71.7-1.8-1.8-1.8-1.41.7
Short access day 1 locomotion7.18.812.23.32.93.52.93.3-3.1-2.93.2-2.92.8-3.13.1-2.5-3.1-2.8-2.42.3
Short access day 10 total locomotion0.91.74.02.01.72.01.41.6-1.4-1.21.3-1.30.9-1.10.8-1.6-0.8-0.60.3-0.1
Short access total locomotion3.23.87.92.62.12.81.82.3-2.1-1.82.2-1.91.6-1.91.9-1.8-1.8-1.6-1.01.1
One hour access (0.3 mA shock)1.01.24.90.90.60.90.50.6-1.1-0.81.1-0.80.5-0.81.2-2.2-1.3-1.2-1.41.0
Compulsive drug intake0.70.91.7-1.3-1.3-1.2-1.3-1.00.81.1-0.90.9-1.11.1-0.80.10.60.5-0.1-0.3
One hour access (shock baseline)2.43.64.52.11.82.01.81.8-2.0-2.02.1-1.81.8-1.92.1-2.0-2.0-1.9-1.61.5
Social response proportion2.12.46.91.61.91.81.31.6-1.7-1.81.4-1.40.8-1.71.3-2.6-1.5-1.1-0.9-0.7
Social responses0.20.32.0-0.10.70.10.0-0.50.0-0.3-0.20.0-0.4-0.2-0.1-1.00.10.40.7-1.4
Social time0.10.11.0-0.00.20.30.0-0.2-0.2-0.30.1-0.3-0.2-0.30.4-1.0-0.20.20.2-0.6
Soleus weight1.23.55.01.81.71.72.01.4-1.8-1.82.0-2.02.2-1.82.1-0.9-2.0-2.1-2.02.2
Bone: stiffness4.37.010.43.03.22.83.12.9-2.9-2.92.6-3.12.7-2.52.4-2.4-2.4-2.1-1.31.5
Tibialis anterior weight0.10.31.50.00.7-0.10.5-0.20.1-0.0-0.4-0.40.10.1-0.60.40.50.61.0-1.2
Time to tail flick, vehicle, before self-admin0.30.31.11.00.00.7-0.10.6-0.8-0.20.6-0.5-0.0-0.00.2-1.0-0.5-0.8-0.60.7
Time to tail flick, vehicle, after self-admin0.20.20.70.20.40.50.70.20.1-0.30.3-0.00.8-0.60.40.8-0.3-0.3-0.20.5
Time to tail flick, test, before self-admin2.52.65.31.71.52.01.41.5-1.7-1.61.8-1.71.2-1.61.8-2.3-1.7-1.4-1.30.9
Time to tail flick, test, after self-admin0.30.30.8-0.6-0.8-0.1-0.9-0.50.50.6-0.20.7-0.70.6-0.2-0.40.0-0.1-0.70.5
Delta time to tail flick, vehicle, before/after SA0.40.31.2-0.5-0.3-0.3-0.0-0.60.80.4-0.60.7-0.00.1-0.41.10.50.80.7-0.8
Delta time to tail flick, test, before/after SA1.21.22.0-1.3-1.2-1.2-1.3-1.01.21.3-1.21.4-1.11.3-1.21.21.00.60.4-0.1
Tibia length0.51.32.21.51.31.31.31.5-1.4-1.21.2-1.50.9-1.10.9-1.3-1.0-0.7-0.50.2
Ambulatory time before self-admin0.71.02.70.81.20.51.61.1-0.8-1.30.9-1.11.6-1.31.00.3-0.8-0.7-0.50.6
Ambulatory time after self-admin1.21.43.41.21.80.61.81.3-1.1-1.61.0-1.41.5-1.30.9-0.5-0.8-0.60.00.2
Bone: tissue strength0.20.20.80.10.40.10.60.3-0.0-0.30.2-0.10.7-0.40.30.7-0.1-0.20.10.9
Total heroin consumption0.10.10.5-0.40.50.00.50.1-0.1-0.50.1-0.10.5-0.40.6-0.0-0.2-0.3-0.10.7
Bone: trabecular number0.40.62.60.81.60.91.00.7-0.7-0.70.5-0.70.5-0.80.3-1.1-0.6-0.4-0.3-0.7
Bone: trabecular spacing0.10.10.5-0.4-0.5-0.4-0.2-0.40.4-0.0-0.10.3-0.00.40.20.60.1-0.1-0.00.7
Bone: trabecular thickness0.40.51.40.71.20.80.60.9-0.7-0.50.4-0.70.3-0.70.1-1.2-0.3-0.10.3-0.7
Bone: trabecular tissue density0.81.14.0-0.9-0.7-1.1-0.7-0.91.11.0-1.00.8-0.61.1-0.92.01.21.01.5-0.2
Water consumed over 24 hours0.20.20.7-0.10.2-0.3-0.20.10.30.3-0.50.1-0.40.5-0.60.30.60.50.9-0.9
Number of responses in last shaping day0.30.32.50.60.50.70.20.7-0.6-0.10.3-0.6-0.1-0.20.1-1.6-0.3-0.20.2-0.3