Hub : Genes

Pgs1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr10_103246003_103249667 0.04 0.02 7.2e-05 0.02 0.04 0.04 0.03 5.8e-03 1.2e-04 3.2e-04 2.0e-03
2 Brain isoform ratio XM_006247855.4 0.05 0.03 1.6e-04 0.05 0.05 0.05 0.05 3.8e-05 2.0e-05 2.2e-05 2.6e-05
3 BLA gene expression Pgs1 0.07 0.05 1.5e-04 0.03 0.03 0.01 0.02 1.4e-02 8.9e-03 9.9e-02 1.8e-02
4 Adipose mRNA stability Pgs1 0.03 0.02 8.9e-05 0.03 0.03 0.02 0.03 2.9e-04 5.8e-04 1.2e-03 8.1e-04
5 NAcc isoform ratio XM_006247855.4 0.02 0.02 3.3e-03 0.01 0.01 0 0.01 2.2e-02 9.7e-03 2.6e-01 1.8e-02
6 IL gene expression Pgs1 0.16 0.12 6.4e-03 0.03 0.06 0.05 0.07 5.9e-02 1.7e-02 2.7e-02 1.0e-02
7 NAcc intron excision ratio chr10_103246003_103249667 0.02 0.02 7.5e-03 0.01 0.01 0.01 0.01 2.6e-02 1.1e-02 2.4e-02 2.5e-02
8 PL gene expression Pgs1 0.1 0.07 1.4e-07 0.07 0.06 0.06 0.07 6.5e-08 1.1e-06 6.4e-07 3.9e-08
9 PL isoform ratio XM_006247855.4 0.03 0.02 2.4e-03 0.02 0.02 0.03 0.02 1.2e-03 2.9e-03 7.5e-04 1.8e-03
10 Liver mRNA stability Pgs1 0.05 0.04 1.7e-04 0.03 0.02 0.02 0.02 6.1e-04 1.7e-03 3.7e-03 1.0e-03
11 Brain isoform ratio XM_221142.10 0.08 0.05 6.4e-05 0.06 0.05 0.05 0.06 5.0e-06 1.3e-05 8.1e-06 6.3e-06
12 Brain gene expression Pgs1 0.32 0.15 2.8e-15 0.17 0.17 0.15 0.17 2.3e-15 1.3e-15 3.8e-14 1.6e-15
13 IL intron excision ratio chr10_103228179_103229807 0.15 0.11 4.1e-03 -0.01 0.01 -0.01 -0.01 7.6e-01 2.2e-01 5.0e-01 6.6e-01
14 OFC gene expression Pgs1 0.25 0.16 1.8e-03 0.05 0.07 0.06 0.07 2.5e-02 1.0e-02 1.4e-02 8.4e-03
15 Brain mRNA stability Pgs1 0.12 0.09 2.3e-09 0.09 0.1 0.12 0.11 2.3e-08 1.2e-09 3.6e-11 2.2e-10
16 IL intron excision ratio chr10_103225516_103228102 0.18 0.12 2.2e-03 -0.01 0.02 -0.01 -0 7.0e-01 1.1e-01 4.7e-01 3.9e-01
17 Liver intron excision ratio chr10_103233322_103241803 0.04 0.04 4.2e-04 0.03 0.03 0.02 0.03 2.0e-04 8.6e-04 1.4e-03 4.7e-04
18 Liver intron excision ratio chr10_103246003_103249667 0.05 0.04 1.1e-05 0.05 0.04 0.04 0.05 1.8e-06 1.4e-05 8.3e-06 4.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.91.53.6-1.7-0.9-1.2-0.5-1.7-0.3-1.7-1.6-0.3-1.5-1.5-0.9-0.70.4-1.90.5-1.11.1
Area under the delay curve1.51.65.41.01.01.30.51.22.31.31.00.11.40.90.81.61.80.4-1.61.5-1.5
BMI with tail0.72.210.70.60.2-0.50.20.0-3.3-0.30.72.80.20.50.9-1.8-2.81.22.0-1.11.1
BMI without tail1.02.03.5-1.4-1.3-1.6-1.6-1.6-1.9-1.6-0.9-0.8-1.1-1.1-0.6-1.7-1.4-0.61.7-1.81.8
Body weight0.52.15.02.01.51.21.11.7-0.71.52.01.21.91.71.90.2-1.02.20.00.8-0.8
Weight adjusted by age0.10.10.4-0.10.30.20.3-0.10.5-0.10.0-0.3-0.00.40.30.30.6-0.5-0.4-0.20.2
Bone surface1.12.010.8-0.11.31.11.20.12.70.20.50.10.90.61.11.93.3-0.2-2.30.9-0.9
Bone volume0.50.85.4-0.90.50.10.5-0.81.7-0.7-0.2-0.40.0-0.10.50.82.3-1.0-1.2-0.00.0
Breakpoint value in progressive ratio session0.40.51.7-0.40.70.00.8-0.60.1-0.60.7-0.40.70.81.30.01.10.4-0.3-0.90.9
Number of licking bursts0.10.10.30.20.10.2-0.50.20.30.30.2-0.30.50.00.10.20.20.3-0.10.3-0.3
Context. condit. distance diff. score0.30.41.20.20.70.50.90.20.50.20.60.50.50.70.80.61.10.6-0.70.2-0.2
Locomotion velocity, session 10.60.61.71.10.40.90.11.30.81.30.4-0.10.50.3-0.10.8-0.20.4-0.61.3-1.3
Locomotion distance, session 12.93.87.8-1.6-2.1-2.0-2.2-1.6-1.6-1.6-1.8-2.8-1.9-1.7-1.9-2.1-2.2-2.02.1-1.71.7
Locomotion velocity, session 20.70.81.6-0.8-0.9-0.9-0.7-0.8-0.7-0.9-1.1-0.2-1.1-0.9-1.1-0.9-0.7-1.30.9-0.70.7
Locomotion distance, session 26.08.411.0-2.7-3.1-3.1-2.8-2.7-2.5-2.8-3.2-2.0-3.2-3.0-3.0-3.1-3.0-3.33.1-2.72.7
Locomotion velocity, session 30.20.20.70.4-0.30.3-0.40.60.70.7-0.2-0.60.3-0.1-0.60.5-0.20.1-0.30.8-0.8
Locomotion distance, session 30.50.53.00.1-0.6-0.6-0.6-0.0-1.5-0.1-0.3-0.2-0.1-0.4-0.5-1.0-1.70.41.2-0.40.4
Stereotopy head waving bouts, day 31.92.24.21.41.91.61.91.21.21.21.71.11.52.01.81.41.41.2-1.51.1-1.1
Stereotopy head waving duration, day 32.12.54.41.22.01.72.01.11.71.11.61.11.42.01.91.72.10.9-1.91.1-1.1
Locomotion velocity, session 70.10.21.0-0.4-0.3-0.1-0.4-0.20.6-0.1-0.3-1.0-0.1-0.4-0.40.30.6-0.2-0.40.1-0.1
Locomotion distance, session 72.53.25.1-2.3-1.8-2.0-1.5-2.2-1.3-2.2-1.8-1.5-1.7-2.0-1.5-1.7-0.8-1.61.5-2.02.0
Stereotopy head waving bouts, day 73.84.35.62.02.42.22.22.01.72.02.31.82.22.22.32.11.92.1-2.11.9-1.9
Stereotopy head waving duration, day 75.77.08.72.62.93.02.82.62.72.62.61.82.52.52.62.92.72.1-2.92.7-2.7
Locomotion velocity, session 80.70.92.60.40.81.00.70.61.60.70.40.30.60.50.41.41.60.3-1.51.1-1.1
Locomotion distance, session 82.53.75.1-2.2-1.9-2.2-1.6-2.3-1.6-2.3-1.9-1.7-2.0-1.7-1.6-2.0-1.2-2.11.8-2.22.2
Degree of sensitization distance2.92.96.3-2.5-1.6-1.7-1.4-2.30.2-2.2-1.9-1.6-1.9-1.9-1.5-0.90.6-2.50.5-1.71.7
Degree of sensitization stereotypy1.71.92.71.41.51.51.31.41.01.41.51.21.61.31.51.41.11.7-1.41.3-1.3
Conditioned locomotion0.20.31.1-0.6-0.4-0.5-0.7-0.6-0.1-0.6-0.3-1.1-0.4-0.2-0.2-0.4-0.1-0.70.4-0.50.5
Cocaine response after cond. corrected0.30.31.10.50.70.50.60.4-0.00.30.81.10.70.90.70.20.00.7-0.20.1-0.1
Cocaine response after cond. not corrected0.10.10.30.20.40.30.30.20.40.30.40.50.40.50.30.40.30.2-0.40.3-0.3
Cocaine response before conditioning0.30.41.0-0.6-0.5-0.1-0.5-0.31.0-0.1-0.8-1.0-0.4-0.9-0.90.50.9-0.9-0.60.3-0.3
Saline control response0.60.82.2-0.0-0.80.2-1.50.51.30.7-0.8-1.1-0.0-0.9-1.50.90.8-0.2-0.81.1-1.1
Bone: connectivity density1.01.63.6-1.8-1.1-1.1-0.9-1.60.0-1.5-1.9-0.4-1.7-1.9-1.4-0.40.6-1.70.2-0.90.9
Bone: cortical apparent density1.92.56.7-1.0-1.2-1.5-0.7-1.2-2.6-1.5-1.40.8-1.6-1.2-1.2-2.1-2.3-1.12.1-1.81.8
Bone: cortical area2.43.67.62.42.21.92.52.10.11.82.12.82.02.42.30.9-0.11.9-0.71.5-1.5
Bone: cortical porosity1.92.12.81.51.61.71.61.51.71.51.21.31.11.21.21.71.40.8-1.61.6-1.6
Bone: cortical porosity2.83.14.21.71.92.01.91.72.11.71.61.61.51.41.62.01.81.1-2.01.8-1.8
Bone: cortical thickness1.72.713.51.70.30.20.71.3-3.00.80.53.50.20.70.2-1.4-3.71.22.00.1-0.1
Bone: cortical thickness1.21.410.21.10.10.10.20.8-1.80.60.33.20.20.30.2-0.9-2.50.81.30.1-0.1
Bone: cortical tissue density2.02.66.5-1.0-1.2-1.5-0.7-1.3-2.6-1.5-1.50.8-1.7-1.3-1.2-2.1-2.3-1.22.1-1.81.8
Condit. Reinf. active minus inactive responses0.10.20.4-0.5-0.4-0.3-0.5-0.40.4-0.3-0.40.2-0.6-0.5-0.5-0.00.4-0.7-0.1-0.20.2
Condit. Reinf. active-inactive response ratio0.40.41.7-0.8-0.1-0.20.1-0.70.8-0.7-0.6-0.3-0.9-0.4-0.30.21.1-1.3-0.4-0.40.4
Condit. Reinf. active responses0.60.71.9-0.8-1.1-0.8-1.4-0.70.0-0.6-1.0-0.5-1.1-1.0-1.2-0.5-0.3-1.10.5-0.40.4
Condit. Reinf. inactive responses0.81.03.4-0.8-1.4-1.1-1.9-0.6-0.6-0.5-0.9-1.1-0.7-1.1-1.3-0.9-1.2-0.61.0-0.50.5
Incentive salience index mean0.10.10.4-0.2-0.2-0.0-0.4-0.10.6-0.0-0.30.1-0.4-0.3-0.40.20.5-0.5-0.30.1-0.1
Condit. Reinf. lever presses0.10.20.6-0.3-0.5-0.3-0.8-0.20.3-0.2-0.3-0.7-0.4-0.4-0.4-0.2-0.1-0.80.2-0.10.1
Condit. Reinf. active minus inactive responses0.50.72.20.40.50.80.50.61.50.70.4-1.10.50.40.31.11.30.0-1.20.8-0.8
Condit. Reinf. active-inactive response ratio0.20.30.80.30.20.50.10.50.90.60.2-0.40.20.1-0.00.70.80.2-0.70.6-0.6
Condit. Reinf. active responses0.20.31.3-0.6-0.1-0.2-0.0-0.50.6-0.4-0.3-1.1-0.3-0.2-0.10.20.9-0.9-0.4-0.30.3
Condit. Reinf. inactive responses0.60.72.0-1.2-0.7-0.8-0.6-1.1-0.1-1.1-0.9-1.1-0.9-0.8-0.7-0.50.1-1.40.4-0.90.9
Condit. Reinf. lever presses1.11.54.8-1.6-1.1-1.2-1.1-1.50.2-1.4-1.3-1.5-1.5-1.2-1.0-0.70.2-2.20.4-1.21.2
Condit. Reinf. lever reinforcers received0.20.31.0-0.8-0.1-0.4-0.0-0.80.3-0.8-0.3-1.0-0.4-0.30.0-0.10.7-1.0-0.1-0.70.7
Conditioned reinforcement - actives1.11.12.6-1.0-0.9-1.1-0.9-1.1-0.9-1.1-0.7-1.6-0.8-1.0-0.5-1.1-0.9-1.01.1-1.21.2
Conditioned reinforcement - inactives0.20.20.40.60.50.50.70.6-0.10.50.4-0.20.40.30.40.3-0.20.5-0.30.5-0.5
Conditioned locomotion1.31.64.2-1.3-1.0-1.3-0.8-1.4-1.0-1.5-0.9-2.0-0.9-1.0-0.5-1.4-1.0-1.41.3-1.61.6
Patch foraging indifference point 0 sec1.11.88.0-1.6-1.4-1.5-1.3-1.5-0.6-1.5-1.0-2.8-1.0-0.8-1.0-1.2-0.6-1.51.1-1.41.4
Patch foraging indifference point AUC1.71.94.8-1.5-1.9-1.4-2.2-1.2-0.3-1.1-1.8-1.2-1.5-1.9-2.1-0.8-0.2-1.40.8-0.80.8
Delay disc. indifference point, 0s delay1.31.42.81.30.91.30.81.51.61.50.81.00.90.80.41.40.60.2-1.21.7-1.7
Delay disc. indifference point, 16s delay0.30.30.6-0.7-0.5-0.5-0.8-0.70.2-0.6-0.5-0.7-0.4-0.5-0.4-0.30.5-0.60.2-0.50.5
Delay disc. indifference point, 2s delay0.80.93.90.60.60.70.20.72.00.80.7-1.71.30.50.51.01.1-0.4-1.00.9-0.9
Delay disc. indifference point, 24s delay0.10.10.4-0.2-0.2-0.1-0.4-0.10.5-0.1-0.40.3-0.4-0.2-0.40.00.5-0.6-0.10.1-0.1
Delay disc. indifference point, 4s delay1.61.74.41.21.01.40.61.42.11.51.00.11.50.90.71.61.50.5-1.61.6-1.6
Delay disc. indifference point, 8s delay4.64.88.52.02.02.31.42.22.92.41.91.12.21.71.52.62.51.8-2.62.6-2.6
Indifference point function ln k0.60.82.80.60.70.01.30.1-1.7-0.20.71.20.40.91.1-0.9-1.60.51.0-0.60.6
Indifference point function log k0.60.82.80.60.70.01.30.1-1.7-0.20.71.20.40.91.1-0.9-1.60.51.0-0.60.6
Patch foraging total patch changes 0 sec1.52.47.5-1.8-1.6-1.7-1.4-1.8-0.8-1.7-1.3-2.7-1.3-1.0-1.1-1.5-0.7-1.81.4-1.61.6
Patch foraging total patch changes 12 sec3.74.88.0-2.4-2.7-2.5-2.8-2.2-1.4-2.1-2.3-2.3-2.3-2.2-2.5-2.0-1.4-2.01.9-1.91.9
Patch foraging total patch changes 18 sec2.43.111.8-2.3-1.9-1.8-2.4-2.00.4-1.8-1.6-3.4-1.3-1.7-1.6-0.90.7-1.80.6-1.31.3
Patch foraging total patch changes 24 sec0.40.52.7-0.2-0.10.2-0.30.11.60.30.1-1.30.10.3-0.20.81.6-0.2-0.90.6-0.6
Patch foraging total patch changes 6 sec1.92.85.2-1.8-1.9-1.8-2.3-1.7-1.1-1.7-1.8-1.4-1.8-1.6-1.8-1.6-0.9-1.71.5-1.51.5
Patch foraging time to switch 0 sec0.30.51.00.70.80.80.70.70.30.70.70.90.80.50.70.80.61.0-0.80.7-0.7
Patch foraging water rate 0 sec0.71.14.0-1.2-1.3-1.1-1.4-1.1-0.1-1.0-0.9-2.0-1.0-0.7-1.1-0.8-0.3-1.10.8-0.90.9
Patch foraging water rate 12 sec0.71.14.6-0.2-0.3-0.80.1-0.6-2.1-0.8-0.01.5-0.60.30.1-1.5-1.60.01.6-1.21.2
Patch foraging water rate 18 sec0.30.41.2-0.8-0.3-0.7-0.2-0.9-0.7-1.0-0.5-0.0-0.4-0.3-0.1-0.7-0.2-0.60.6-1.11.1
Patch foraging water rate 24 sec1.52.13.4-1.8-1.4-1.7-1.7-1.9-0.9-1.8-1.2-1.5-1.3-1.1-1.0-1.4-0.4-1.11.3-1.81.8
Patch foraging water rate 6 sec0.30.52.40.1-0.4-0.5-0.3-0.1-1.4-0.3-0.11.0-0.30.2-0.2-1.0-1.6-0.01.2-0.50.5
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.2-0.7-0.3-0.2-0.1-0.1-0.1-0.7-0.4-0.6-0.9-1.0-0.1-0.3-0.40.20.1-0.1
Distance traveled before self-admin1.21.32.71.10.91.30.91.31.41.40.9-0.30.90.70.61.40.80.7-1.41.6-1.6
Distance traveled after self-admin1.21.42.8-1.7-1.0-1.3-0.9-1.7-0.3-1.6-1.1-1.6-1.0-1.0-0.7-0.90.2-1.30.7-1.41.4
Extensor digitorum longus weight1.45.58.3-2.1-2.4-2.6-2.5-2.3-2.8-2.3-2.0-1.6-2.0-2.1-1.7-2.8-2.8-1.92.9-2.52.5
Bone: elastic displacement1.61.96.2-0.6-1.2-1.3-0.7-0.8-2.3-1.0-1.20.9-1.3-0.9-1.2-1.8-2.5-1.02.0-1.11.1
Bone: elastic work0.60.84.01.00.60.41.00.7-1.40.40.52.00.30.80.7-0.5-1.40.70.70.2-0.2
Bone: endosteal estimation1.63.415.8-0.11.91.31.7-0.03.20.21.6-1.11.61.62.42.04.0-0.0-2.50.7-0.7
Bone: endosteal perimeter4.910.126.21.73.63.13.11.84.92.03.0-0.23.13.13.63.85.11.3-4.32.6-2.6
Epididymis fat weight0.20.62.40.40.50.00.40.1-1.0-0.10.91.60.70.91.1-0.6-0.81.00.7-0.60.6
Delta time in closed arm before/after self-admin0.70.72.90.40.70.70.40.51.30.60.80.30.50.60.51.11.70.9-1.20.8-0.8
Delta time in open arm before/after self-admin1.21.12.1-1.0-1.3-1.1-1.2-0.9-0.5-0.9-1.5-0.4-1.1-1.5-1.3-0.9-0.9-1.30.9-0.70.7
Diff in mean of infusions in LGA sessions0.91.03.00.21.30.71.10.01.10.01.2-0.71.31.21.70.71.70.6-1.0-0.30.3
Delay discount exponential model param1.92.06.2-1.1-1.2-1.4-0.7-1.3-2.5-1.5-1.2-0.3-1.6-1.0-0.9-1.7-1.9-0.61.7-1.61.6
Extinction: sum of active levers before priming0.10.10.20.20.1-0.00.10.0-0.4-0.10.10.20.00.30.2-0.3-0.50.00.4-0.10.1
Active lever presses in extinction session 60.30.30.8-0.6-0.1-0.4-0.3-0.7-0.8-0.70.0-0.3-0.40.20.3-0.4-0.10.10.3-0.90.9
Bone: final force1.11.76.31.71.51.41.71.50.01.31.22.50.91.41.20.80.31.3-0.61.1-1.1
Bone: final moment1.11.86.21.71.61.51.81.50.11.31.32.50.91.51.30.80.41.3-0.71.1-1.1
Food consumed during 24 hour testing period0.40.52.1-0.2-0.20.2-0.70.11.40.3-0.3-0.9-0.3-0.3-0.50.91.4-0.3-0.90.7-0.7
Glucose0.30.42.80.30.3-0.00.30.0-1.1-0.10.21.70.5-0.10.5-0.5-0.80.90.6-0.50.5
Heart weight0.50.72.20.90.60.20.90.5-1.50.20.90.50.50.91.1-0.7-1.40.90.9-0.30.3
Delay discount hyperbolic model param1.71.86.0-1.1-1.1-1.3-0.6-1.3-2.4-1.4-1.10.1-1.6-1.0-0.9-1.6-1.8-0.41.7-1.51.5
Intermittent access intake day 1-15 change0.30.31.00.60.10.5-0.00.80.50.80.10.50.3-0.2-0.30.70.30.7-0.71.0-1.0
Intermittent access intake escalation0.20.20.60.2-0.10.3-0.20.40.70.5-0.1-0.10.1-0.4-0.40.70.60.4-0.70.8-0.8
Intermittent access intake escalation 20.20.20.6-0.3-0.6-0.2-0.8-0.1-0.00.0-0.5-0.5-0.3-0.8-0.70.10.00.1-0.10.2-0.2
Intermitt. access day 1 inactive lever presses2.02.23.01.51.61.71.71.51.31.51.3-0.31.51.41.41.71.31.3-1.71.6-1.6
Intermitt. access day 15 inactive lever presses0.20.30.7-0.6-0.7-0.5-0.8-0.5-0.3-0.4-0.8-0.4-0.3-0.8-0.7-0.3-0.3-0.30.3-0.30.3
Intermitt. access escalation Index1.11.02.90.60.91.00.70.81.50.90.50.80.60.70.51.31.70.7-1.41.1-1.1
Intermittent access day 1 total infusions0.20.21.00.20.60.10.7-0.1-0.3-0.20.5-0.60.40.71.0-0.3-0.20.00.3-0.50.5
Intermittent access day 15 total infusions0.10.10.60.00.20.20.20.10.40.10.1-0.70.10.00.20.30.50.0-0.40.2-0.2
Intermittent access terminal intake (last 3 days)0.20.20.40.30.60.50.50.30.50.30.5-0.50.40.40.60.50.60.4-0.60.4-0.4
Intermittent access total infusions0.10.20.60.20.60.30.70.10.20.00.5-0.50.40.50.80.20.40.2-0.3-0.00.0
Intermittent access day 1 locomotion0.70.71.8-0.9-0.5-0.9-0.4-1.0-0.6-1.1-0.6-1.3-0.7-0.5-0.1-1.0-0.5-1.00.9-1.21.2
Intermittent access day 15 total locomotion0.20.22.20.20.30.10.60.1-0.30.00.3-1.50.40.30.5-0.1-0.30.20.1-0.10.1
Intermittent access total locomotion0.40.52.8-0.6-0.3-0.6-0.2-0.7-0.6-0.8-0.4-1.7-0.3-0.4-0.0-0.8-0.6-0.60.7-0.90.9
Intermittent access standard deviation4.24.46.72.42.32.22.22.31.12.32.32.02.62.12.31.90.92.6-1.72.0-2.0
Left kidney weight2.77.611.23.33.13.02.93.11.63.03.31.73.03.23.12.41.23.1-2.22.5-2.5
Right kidney weight0.92.54.62.11.81.71.82.00.51.91.90.71.81.91.81.1-0.11.7-0.91.5-1.5
Cocaine induced anxiety0.80.93.00.70.50.90.40.91.11.00.31.70.40.20.01.21.00.7-1.11.3-1.3
Post-drug Anxiety0.20.20.6-0.2-0.30.1-0.50.00.70.2-0.30.7-0.1-0.2-0.60.50.80.1-0.60.5-0.5
Baseline Anxiety0.10.10.7-0.2-0.1-0.3-0.1-0.2-0.5-0.3-0.0-0.80.00.10.1-0.4-0.6-0.10.4-0.40.4
Tail length0.31.19.2-1.0-0.8-0.5-1.3-0.71.3-0.4-0.7-3.0-0.3-0.9-0.80.41.0-0.8-0.5-0.00.0
Length with tail1.14.05.32.12.02.21.52.22.32.32.1-0.42.11.91.82.21.61.8-2.12.2-2.2
Length without tail3.47.411.93.53.03.03.13.21.23.03.22.72.83.22.92.00.72.9-1.82.6-2.6
Times rat made contact with spout0.20.30.7-0.7-0.6-0.5-0.8-0.60.2-0.5-0.6-0.7-0.6-0.7-0.6-0.20.3-0.50.2-0.30.3
Lifetime Intake0.20.20.90.40.70.40.80.2-0.10.20.70.30.40.70.90.20.20.4-0.30.0-0.0
Liver weight, left2.94.66.02.32.42.32.32.21.42.12.32.42.42.22.22.01.72.4-1.91.9-1.9
Liver weight, right0.81.42.61.61.21.30.91.50.41.41.40.81.31.21.20.8-0.11.5-0.71.2-1.2
Locomotor activity0.10.21.6-0.2-0.1-0.20.1-0.20.3-0.2-0.2-1.3-0.7-0.0-0.1-0.2-0.1-1.00.2-0.30.3
Locomotor testing distance0.20.31.0-0.40.40.00.7-0.50.8-0.4-0.0-1.0-0.50.20.40.21.0-1.0-0.4-0.30.3
Locomotor testing rearing1.01.64.1-1.5-1.3-1.2-1.0-1.40.1-1.3-1.5-1.9-1.6-1.4-1.3-0.80.0-2.00.6-0.90.9
Locomotion in novel chamber0.60.71.6-1.2-0.7-0.5-1.1-0.91.0-0.7-1.0-0.6-0.7-1.0-0.80.31.3-1.1-0.5-0.10.1
Locomotion in novel chamber post-restriction0.30.42.6-0.10.60.50.5-0.01.10.00.30.00.20.50.50.91.60.2-1.10.1-0.1
Fecal boli incidents, locomotor time 10.50.61.6-0.9-0.3-0.8-0.2-1.1-0.6-1.2-0.40.0-0.4-0.20.2-0.9-0.3-1.00.7-1.31.3
Change in fecal boli incidents, locomotor task0.20.20.5-0.1-0.3-0.3-0.2-0.2-0.4-0.2-0.1-0.7-0.2-0.1-0.2-0.5-0.7-0.40.6-0.40.4
Time >=10cm from walls, locomotor time 10.30.31.4-0.10.20.40.20.11.10.2-0.1-0.50.1-0.2-0.10.81.2-0.1-0.90.5-0.5
Bouts of movement, locomotor time 10.30.31.90.2-0.2-0.2-0.00.1-0.7-0.00.01.40.0-0.1-0.0-0.6-1.30.00.7-0.30.3
Total resting periods, locomotor time 10.30.31.90.1-0.3-0.3-0.1-0.1-0.7-0.2-0.21.4-0.1-0.3-0.1-0.7-1.2-0.10.8-0.40.4
Rest time, locomotor task time 10.40.41.70.70.60.30.90.4-1.00.30.71.30.50.60.9-0.2-0.70.90.3-0.10.1
Distance moved, locomotor task time 10.40.54.6-0.5-0.6-0.3-0.8-0.30.5-0.2-0.7-2.1-0.5-0.6-0.90.20.6-0.4-0.20.1-0.1
Vertical activity count, locomotor time 11.31.46.4-1.3-1.4-1.2-1.8-1.1-0.1-0.9-1.2-2.5-0.8-1.1-1.3-0.7-0.3-0.80.6-0.70.7
Time >=10cm from walls, locomotor time 20.40.41.0-0.3-0.7-0.5-0.5-0.3-0.9-0.4-0.8-0.3-1.0-0.9-1.0-0.6-1.0-0.40.7-0.30.3
Bouts of movement, locomotor time 20.20.20.60.30.70.40.80.20.30.20.6-0.10.30.50.80.40.70.5-0.50.2-0.2
Total resting periods, locomotor time 20.20.30.80.20.70.40.90.10.40.10.6-0.20.30.50.90.40.80.4-0.50.1-0.1
Rest time, locomotor task time 20.70.82.80.41.20.71.40.30.70.31.10.31.11.01.70.61.10.7-0.80.1-0.1
Distance moved, locomotor task time 20.40.41.70.0-0.8-0.4-0.80.1-0.90.1-0.7-0.7-0.6-0.4-1.1-0.6-1.3-0.30.80.0-0.0
Vertical activity count, locomotor time 20.40.41.4-0.2-0.7-0.6-0.7-0.3-0.8-0.3-0.2-1.2-0.20.0-0.5-0.8-1.2-0.20.9-0.50.5
Light reinforcement 12.03.67.5-1.8-2.3-2.1-2.4-1.7-1.7-1.7-1.9-2.7-1.7-1.8-2.1-1.8-1.8-1.41.9-1.61.6
Light reinforcement 20.20.31.2-0.1-0.8-0.4-1.10.0-0.60.1-0.4-0.9-0.1-0.2-0.9-0.3-0.80.40.40.0-0.0
Bone: marrow area1.63.516.0-0.02.01.31.70.03.30.31.6-1.01.71.72.42.14.00.0-2.60.7-0.7
Bone: maximum diameter6.411.817.53.04.23.74.12.93.52.93.72.13.83.84.23.53.52.6-3.63.0-3.0
Bone: maximum force1.11.95.61.51.81.42.01.2-0.11.01.52.41.11.81.80.70.51.4-0.70.8-0.8
Bone: maximum moment1.12.05.01.51.91.42.21.2-0.01.01.52.21.11.91.80.80.61.3-0.70.8-0.8
Mean time between licks in bursts0.10.22.60.20.10.10.30.1-0.20.1-0.11.6-0.3-0.3-0.0-0.1-0.4-0.30.1-0.00.0
Mean num. licks in bursts0.50.61.2-0.9-0.8-0.8-0.3-0.9-0.6-1.0-0.9-0.2-1.1-0.7-0.7-0.8-0.4-0.90.7-1.01.0
Cd content in liver1.21.34.6-0.5-0.8-1.1-0.5-0.8-2.1-1.0-0.80.9-0.8-0.9-0.6-1.6-1.9-0.31.7-1.21.2
Co content in liver0.50.61.5-0.8-0.6-0.9-0.2-0.9-1.2-1.0-0.60.7-0.6-0.5-0.4-1.0-0.6-0.50.9-1.01.0
Cu content in liver0.00.10.40.20.00.00.00.2-0.30.20.1-0.20.10.40.1-0.2-0.60.00.20.2-0.2
Fe content in liver0.40.52.4-0.10.30.40.10.01.60.20.2-0.60.30.20.30.91.5-0.4-1.10.6-0.6
K content in liver0.20.20.6-0.1-0.20.10.00.10.60.1-0.5-0.8-0.3-0.1-0.60.40.6-0.4-0.40.4-0.4
Mg content in liver1.71.73.0-1.5-1.4-1.3-1.0-1.4-0.8-1.4-1.7-1.1-1.7-1.4-1.6-1.0-0.5-1.70.9-1.11.1
Mn content in liver0.91.01.51.00.91.10.51.20.91.20.80.50.90.90.51.20.91.1-1.11.2-1.2
Na content in liver0.60.61.90.50.50.80.60.71.30.70.1-0.10.40.50.01.11.40.0-1.11.1-1.1
Rb content in liver2.63.24.2-1.8-2.0-1.9-1.9-1.8-1.6-1.8-2.0-0.6-2.0-2.1-1.9-1.8-1.6-1.61.7-1.81.8
Se content in liver0.60.72.2-0.8-0.8-0.4-1.1-0.51.0-0.4-1.0-1.5-0.9-1.0-1.20.20.7-1.2-0.30.1-0.1
Sr content in liver0.20.20.80.50.20.20.40.4-0.90.30.30.60.30.40.1-0.2-0.60.70.40.1-0.1
Zn content in liver1.21.32.61.31.31.31.61.30.71.11.11.10.91.41.20.90.50.8-0.81.2-1.2
Bone: minimum diameter2.34.37.61.62.52.22.81.52.71.52.00.42.12.32.42.32.70.7-2.41.9-1.9
Time in familiar zone, hab. session 10.10.10.3-0.1-0.4-0.3-0.2-0.1-0.3-0.1-0.2-0.1-0.2-0.2-0.2-0.3-0.6-0.10.4-0.10.1
Time in novel zone, hab. session 10.40.40.70.60.60.70.50.70.60.70.30.80.30.30.20.80.70.4-0.80.8-0.8
Total zone transitions, hab. session 12.23.16.0-1.8-1.8-1.8-1.7-1.7-1.1-1.8-2.1-0.8-2.3-1.8-1.9-1.7-1.2-2.51.6-1.61.6
Total locomotion distance, hab. session 11.92.74.1-1.6-1.8-1.7-1.7-1.5-1.2-1.6-1.7-1.7-1.9-1.5-1.7-1.7-1.5-2.01.7-1.51.5
Locomotion velocity, hab. session 12.63.65.1-1.8-2.1-2.0-2.0-1.8-1.5-1.8-1.9-2.1-2.1-1.7-1.9-2.0-1.8-2.32.0-1.81.8
Time in familiar zone, hab. session 20.10.10.6-0.2-0.2-0.3-0.0-0.3-0.8-0.3-0.00.0-0.10.1-0.0-0.4-0.30.30.4-0.40.4
Time in novel zone, hab. session 20.40.40.80.60.70.70.80.60.80.60.40.90.40.40.40.80.80.2-0.80.7-0.7
Total zone transitions, hab. session 26.07.810.2-3.0-2.9-3.1-2.5-3.1-2.3-3.1-3.0-1.6-2.9-2.7-2.6-2.9-2.1-3.22.8-3.03.0
Total locomotion distance, hab. session 26.07.99.7-2.8-3.0-3.1-2.8-2.9-2.8-2.9-2.7-2.4-2.6-2.5-2.6-3.1-2.7-2.63.1-2.92.9
Locomotion velocity, hab. session 26.08.19.8-2.8-3.1-3.1-2.9-2.8-2.7-2.9-2.8-2.6-2.7-2.5-2.7-3.1-2.8-2.83.1-2.92.9
Novel to familiar place preference ratio2.22.33.7-1.8-1.4-1.7-0.8-1.9-1.3-1.9-1.5-0.8-1.9-1.4-1.1-1.6-0.8-1.81.4-1.81.8
Novelty place preference1.71.72.8-1.6-1.1-1.4-0.7-1.7-1.0-1.7-1.3-0.7-1.7-1.2-0.9-1.3-0.6-1.61.1-1.51.5
Time in novel zone, NPP test2.02.13.3-1.7-1.3-1.6-0.8-1.8-1.2-1.8-1.4-0.7-1.8-1.4-1.1-1.4-0.7-1.71.3-1.71.7
Total zone transitions, NPP test4.36.17.9-2.6-2.8-2.7-2.7-2.5-2.1-2.5-2.6-2.0-2.5-2.3-2.6-2.5-2.0-2.72.5-2.42.4
Total locomotion distance, NPP test7.910.814.0-3.1-3.6-3.6-3.5-3.2-3.3-3.2-3.1-3.1-2.9-2.9-3.1-3.7-3.4-3.03.7-3.33.3
Locomotion velocity, NPP test6.79.412.1-2.9-3.4-3.4-3.3-3.0-3.0-3.0-2.9-2.8-2.7-2.7-2.9-3.5-3.1-2.83.5-3.13.1
Intraocular pressure0.60.93.1-1.4-0.5-1.0-0.7-1.5-0.5-1.4-0.3-1.7-0.7-0.40.2-0.60.4-0.40.3-1.31.3
Delta distance traveled before/after self-admin2.93.15.2-2.1-1.6-2.0-1.5-2.2-1.6-2.3-1.8-0.4-1.7-1.6-1.3-1.9-0.8-1.51.8-2.22.2
Delta ambulatory time before/after self-admin3.13.46.0-2.3-1.7-2.1-1.6-2.4-1.5-2.4-2.0-0.6-1.9-1.7-1.4-1.9-0.4-1.71.7-2.32.3
Parametrial fat weight0.10.11.20.10.0-0.10.00.1-0.40.10.4-1.10.20.60.3-0.2-0.30.30.3-0.10.1
Pavlov. Cond. lever latency0.40.41.3-1.2-0.4-0.7-0.1-1.2-0.4-1.1-0.5-0.5-0.5-0.7-0.2-0.30.6-0.10.1-0.90.9
Pavlov. Cond. magazine entry latency2.12.74.51.71.61.91.31.82.11.81.50.01.41.61.31.91.60.9-1.92.0-2.0
Pavlov. Cond. change in total contacts0.40.51.3-0.2-0.3-0.5-0.1-0.4-0.9-0.6-0.50.5-0.7-0.3-0.3-1.0-1.1-0.91.0-0.80.8
Pavlov. Cond. index score1.11.42.31.51.21.40.71.51.41.51.20.21.01.41.01.20.70.6-1.11.4-1.4
Pavlov. Cond. latency score1.51.93.31.81.31.60.81.81.41.81.50.51.31.61.11.30.70.9-1.21.7-1.7
Pavlov. Cond. lever contacts0.10.10.60.60.00.2-0.30.6-0.10.50.20.20.00.3-0.0-0.2-0.8-0.20.40.3-0.3
Pavlov. Cond. magazine entry number2.73.44.5-2.0-2.1-2.1-1.7-2.0-2.0-2.0-1.9-0.8-1.6-2.0-1.7-2.0-1.6-1.21.9-2.02.0
Pavlov. Cond. intertrial magazine entries1.82.23.8-1.8-1.6-1.6-1.5-1.7-1.0-1.7-1.7-0.2-1.6-1.9-1.5-1.3-0.8-1.51.2-1.51.5
Pavlov. Cond. lever-magazine prob. diff.0.70.91.61.21.01.10.61.31.21.20.90.10.71.10.71.00.60.2-0.91.2-1.2
Pavlov. Cond. response bias1.11.32.01.41.31.41.01.41.21.41.20.50.91.31.01.10.80.5-1.01.3-1.3
Pavlov. Cond. lever latency1.31.74.61.81.01.20.91.8-0.31.71.21.91.21.20.70.7-0.52.1-0.41.4-1.4
Pavlov. Cond. magazine entry latency0.40.51.5-0.8-0.2-0.7-0.1-1.0-0.8-1.0-0.1-0.6-0.3-0.20.3-0.8-0.4-0.50.7-1.21.2
Pavlov. Cond. change in total contacts0.91.22.5-1.5-0.8-1.2-0.7-1.6-0.5-1.5-0.9-1.1-0.9-1.0-0.3-1.0-0.2-1.40.7-1.51.5
Pavlov. Cond. index score0.81.12.6-1.4-0.7-1.0-0.6-1.40.0-1.4-0.7-1.6-0.8-0.9-0.2-0.70.1-1.60.5-1.31.3
Pavlov. Cond. latency score0.50.72.0-1.1-0.4-0.8-0.4-1.20.2-1.1-0.4-1.4-0.5-0.60.0-0.50.3-1.30.2-1.11.1
Pavlov. Cond. lever contacts1.41.96.2-1.9-1.2-1.3-1.1-1.70.7-1.6-1.4-2.2-1.4-1.4-1.0-0.60.6-2.50.3-1.21.2
Pavlov. Cond. magazine entry number0.91.12.51.20.71.10.61.30.81.30.51.60.70.70.11.10.61.0-0.91.5-1.5
Pavlov. Cond. intertrial magazine entries1.01.37.2-0.8-0.6-0.1-0.8-0.42.1-0.1-0.7-2.7-0.5-0.4-0.90.82.0-1.4-1.00.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.91.12.7-1.5-0.7-1.1-0.7-1.5-0.0-1.4-0.8-1.6-0.8-0.9-0.2-0.70.1-1.60.5-1.41.4
Pavlov. Cond. response bias1.01.43.4-1.5-1.0-1.2-0.9-1.5-0.0-1.4-1.0-1.7-1.1-1.1-0.6-0.8-0.1-1.80.7-1.31.3
Time in closed arm before self-admin0.20.32.00.2-0.2-0.2-0.10.1-1.00.0-0.20.40.3-0.2-0.2-0.6-1.40.20.7-0.20.2
Time in closed arm after self-admin2.32.33.61.51.81.51.81.41.01.41.81.31.91.71.91.31.21.9-1.31.2-1.2
Time in open arm before self-admin0.40.40.80.60.70.70.70.6-0.10.50.60.90.40.80.50.60.40.9-0.60.6-0.6
Time in open arm after self-admin0.50.60.9-0.9-0.8-0.8-0.9-0.9-0.6-0.8-1.0-0.2-0.9-0.9-0.9-0.5-0.3-0.70.5-0.60.6
Bone: periosteal estimation2.34.79.61.62.82.12.81.42.31.42.51.12.52.63.12.02.61.3-2.21.5-1.5
Bone: periosteal perimeter5.28.612.43.03.53.23.42.82.62.73.31.83.23.43.52.82.32.4-2.82.7-2.7
Bone: post-yield work0.50.71.6-1.1-0.4-0.8-0.1-1.2-0.6-1.3-0.8-0.4-0.8-0.6-0.3-0.80.2-0.90.6-1.21.2
Progressive ratio test 1 active lever presses0.10.10.3-0.6-0.1-0.3-0.0-0.60.2-0.5-0.2-0.4-0.4-0.20.1-0.00.5-0.5-0.1-0.40.4
Progressive ratio test 1 breakpoint0.10.10.3-0.50.0-0.20.1-0.50.0-0.5-0.10.1-0.4-0.00.2-0.10.4-0.3-0.0-0.40.4
Progressive ratio test 1 inactive lever presses0.30.30.70.50.50.60.50.50.80.50.3-0.90.40.30.30.70.40.1-0.70.6-0.6
Progressive ratio test 2 active lever presses0.30.42.9-0.6-0.1-0.5-0.0-0.7-0.4-0.7-0.1-1.7-0.2-0.10.2-0.5-0.1-0.50.4-0.80.8
Progressive ratio test 2 breakpoint0.30.42.1-0.6-0.2-0.5-0.1-0.7-0.5-0.7-0.2-1.5-0.3-0.30.1-0.6-0.3-0.50.5-0.80.8
Progressive ratio test 2 inactive lever presses0.10.10.90.10.10.00.20.0-0.30.00.1-0.90.2-0.10.1-0.0-0.20.20.0-0.00.0
Incentive Sensitization - Responses0.50.51.60.80.80.60.80.7-0.00.61.0-1.31.00.91.00.3-0.30.6-0.20.4-0.4
Incentive Sensitization - Breakpoint0.70.71.51.01.00.80.90.80.10.81.2-1.21.21.01.10.5-0.20.8-0.40.6-0.6
Sum of active levers in priming session hrs 5-60.30.31.10.10.80.40.7-0.10.5-0.10.6-0.10.60.71.00.40.90.1-0.5-0.00.0
Progressive ratio0.20.20.8-0.10.4-0.10.5-0.4-0.2-0.40.5-0.70.50.60.9-0.4-0.10.10.3-0.70.7
Food seeking constrained by brief footshock0.50.61.51.01.00.81.00.80.30.81.2-0.01.11.11.20.50.00.8-0.40.3-0.3
Seeking ratio, punishment vs. effort0.30.30.80.60.30.70.20.80.80.90.20.10.20.1-0.00.80.40.3-0.70.9-0.9
Retroperitoneal fat weight0.41.43.41.11.31.00.71.00.71.01.8-0.51.81.51.81.00.81.6-1.00.7-0.7
Reaction time number correct2.84.07.7-2.6-2.3-2.2-2.8-2.4-1.1-2.3-2.2-1.4-1.8-2.2-2.1-1.6-0.5-1.91.4-1.91.9
Reaction time mean minus median0.50.61.51.20.70.90.91.2-0.11.10.9-0.20.80.80.60.5-0.51.1-0.30.8-0.8
Reaction time mean minus median AUC0.81.02.01.30.91.20.91.40.71.40.90.10.81.00.51.10.21.0-0.91.3-1.3
Reaction time num false alarms0.30.45.1-0.5-0.4-0.5-0.3-0.50.1-0.4-0.1-2.30.1-0.10.1-0.4-0.1-0.20.3-0.50.5
Reaction time num false alarms AUC0.50.76.4-0.8-0.6-0.7-0.4-0.8-0.0-0.8-0.4-2.5-0.1-0.3-0.1-0.6-0.1-0.50.5-0.80.8
Reaction time trials correct on left2.84.07.7-2.6-2.3-2.2-2.8-2.4-1.1-2.3-2.2-1.4-1.8-2.2-2.1-1.6-0.5-1.91.4-1.91.9
Reaction time trials on left2.83.97.6-2.6-2.2-2.2-2.7-2.4-1.1-2.3-2.2-1.5-1.8-2.2-2.0-1.5-0.5-1.91.3-1.91.9
Reaction time mean0.00.10.40.30.30.20.60.3-0.10.20.2-0.00.10.10.30.1-0.30.0-0.00.2-0.2
Reaction time mean AUC0.00.10.40.20.10.00.40.1-0.40.00.1-0.1-0.1-0.00.2-0.2-0.6-0.10.3-0.10.1
Median of all reaction times0.00.00.30.10.20.10.50.10.10.00.00.2-0.0-0.10.2-0.0-0.2-0.20.00.1-0.1
Reaction time omissions0.60.81.41.00.80.90.71.10.81.11.00.01.01.10.80.90.61.2-0.81.0-1.0
Reaction time false alarm rate0.30.42.20.60.60.51.00.50.60.50.7-1.50.80.80.80.30.20.5-0.30.3-0.3
Reaction time premature initiation rate3.04.16.5-1.8-1.8-2.1-1.5-2.0-2.4-2.1-1.91.0-2.5-1.8-1.6-2.4-2.1-2.02.4-2.22.2
Reaction time premature initiations5.67.810.5-3.0-2.8-3.1-2.6-3.2-2.7-3.2-2.80.0-3.2-2.7-2.4-3.0-2.0-2.92.8-3.13.1
Std. dev. reaction times0.10.10.50.50.20.30.40.5-0.50.40.3-0.10.20.30.2-0.0-0.70.40.10.2-0.2
Reaction time trials completed2.83.97.6-2.6-2.2-2.2-2.7-2.4-1.1-2.3-2.2-1.5-1.8-2.2-2.0-1.5-0.5-1.91.3-1.91.9
Reaction time trials AUC3.34.88.7-2.8-2.5-2.4-3.0-2.6-1.3-2.5-2.4-1.5-2.1-2.4-2.2-1.8-0.7-2.11.5-2.12.1
Run reversals in cocaine runway, females0.20.20.70.30.30.2-0.00.30.40.30.7-0.40.80.60.60.1-0.10.2-0.10.2-0.2
Run reversals in cocaine runway, males0.50.51.80.40.3-0.10.30.1-1.3-0.00.60.80.50.80.7-0.7-1.10.90.8-0.60.6
Latency to leave start box in cocaine runway0.40.41.3-0.6-0.4-0.7-0.1-0.7-1.1-0.8-0.30.0-0.6-0.2-0.2-0.9-0.7-0.30.9-0.90.9
Latency to leave start box in cocaine runway, F0.50.61.2-0.8-0.8-0.8-0.6-0.8-1.1-0.8-0.6-0.1-1.0-0.6-0.7-0.8-0.6-0.30.8-0.80.8
Latency to leave start box in cocaine runway, M0.90.81.7-0.8-0.6-1.0-0.4-1.1-1.1-1.2-0.60.0-0.6-0.6-0.2-1.3-1.0-0.91.3-1.21.2
Std. dev. time between licks in bursts1.51.83.2-1.7-1.5-1.4-1.7-1.5-0.4-1.4-1.4-1.5-1.4-1.5-1.4-0.9-0.4-1.80.8-1.01.0
Total sessions with >9 infusions0.80.92.21.01.30.91.40.8-0.10.71.21.40.91.31.50.50.21.0-0.50.4-0.4
Short access day 1 total inactive lever presses0.30.30.90.50.80.61.00.40.10.40.50.60.30.80.80.50.40.4-0.50.3-0.3
Short access day 10 total inactive lever presses1.01.11.91.10.91.21.01.20.71.30.71.31.00.70.51.20.71.2-1.11.4-1.4
Short access day 1 total infusions1.01.12.01.11.41.11.30.90.10.81.21.30.91.41.40.70.51.2-0.70.7-0.7
Short access day 10 total infusions1.21.43.40.91.61.21.60.80.80.71.50.71.11.61.81.01.20.9-1.10.6-0.6
Short access total infusions0.30.30.80.50.70.40.80.3-0.50.20.70.90.30.90.90.0-0.20.6-0.0-0.00.0
Short access day 1 locomotion0.30.31.70.70.70.50.70.6-0.00.50.51.30.60.70.70.2-0.10.6-0.10.3-0.3
Short access day 10 total locomotion0.30.30.60.70.70.60.80.6-0.20.50.60.70.60.70.80.2-0.20.6-0.20.3-0.3
Short access total locomotion0.80.81.61.31.10.81.21.0-0.70.81.11.00.81.21.20.1-0.81.00.10.4-0.4
One hour access (0.3 mA shock)0.20.20.6-0.7-0.1-0.5-0.2-0.7-0.4-0.7-0.3-0.0-0.1-0.20.2-0.40.0-0.20.3-0.80.8
Compulsive drug intake0.80.82.9-0.6-0.7-0.9-0.6-0.7-1.7-0.8-0.7-0.0-0.4-0.6-0.4-1.1-1.5-0.11.1-0.90.9
One hour access (shock baseline)0.20.20.9-0.10.20.20.1-0.10.90.00.1-0.70.20.00.30.50.9-0.2-0.60.1-0.1
Social response proportion0.60.61.5-0.5-0.7-0.8-0.9-0.6-1.2-0.7-0.4-0.4-0.2-0.7-0.3-1.1-1.2-0.31.1-0.90.9
Social responses0.20.30.9-0.1-0.7-0.4-1.0-0.1-0.6-0.1-0.50.2-0.4-0.8-0.8-0.5-0.9-0.40.6-0.10.1
Social time0.81.03.2-0.6-1.0-1.0-0.8-0.7-1.6-0.8-0.7-0.4-0.8-0.7-0.7-1.3-1.8-0.71.4-1.11.1
Soleus weight0.82.46.2-0.8-1.7-1.6-1.9-0.9-2.4-1.0-1.3-0.8-1.2-1.4-1.5-2.0-2.5-0.72.2-1.31.3
Bone: stiffness1.32.15.91.81.71.51.81.60.31.41.62.41.31.51.60.90.41.6-0.81.2-1.2
Tibialis anterior weight0.20.71.9-0.4-0.7-0.8-0.7-0.6-1.3-0.7-0.7-0.2-0.5-0.6-0.5-1.2-1.4-0.71.2-0.70.7
Time to tail flick, vehicle, before self-admin1.01.02.9-0.4-1.2-0.9-1.2-0.4-1.0-0.4-1.10.4-1.3-1.1-1.3-1.0-1.7-1.11.2-0.40.4
Time to tail flick, vehicle, after self-admin1.51.64.71.51.31.01.51.2-0.91.01.52.21.51.41.50.2-0.71.9-0.00.6-0.6
Time to tail flick, test, before self-admin0.60.53.0-0.7-0.7-0.4-0.6-0.50.7-0.4-0.7-1.7-0.9-0.7-0.7-0.00.2-1.4-0.00.1-0.1
Time to tail flick, test, after self-admin0.70.71.40.90.90.80.70.80.20.81.11.21.11.01.10.60.21.1-0.60.6-0.6
Delta time to tail flick, vehicle, before/after SA0.30.31.10.20.70.30.80.1-0.30.00.8-0.20.90.81.00.10.30.9-0.2-0.10.1
Delta time to tail flick, test, before/after SA1.71.65.21.51.31.11.01.3-0.41.21.42.31.51.41.30.6-0.12.1-0.50.6-0.6
Tibia length11.733.144.26.65.96.35.26.64.66.66.23.46.35.85.35.73.66.4-5.36.1-6.1
Ambulatory time before self-admin1.91.93.81.51.11.51.11.71.51.81.2-0.91.31.00.81.60.61.1-1.52.0-2.0
Ambulatory time after self-admin0.40.41.1-1.0-0.5-0.7-0.4-1.0-0.2-1.0-0.8-0.9-0.6-0.4-0.4-0.40.4-0.70.2-0.70.7
Bone: tissue strength0.90.92.0-0.9-0.5-0.90.1-1.1-1.4-1.2-0.7-0.6-1.1-0.3-0.3-1.1-0.7-0.81.0-1.31.3
Total heroin consumption2.53.05.21.62.21.82.31.41.41.42.00.71.92.22.21.61.81.7-1.61.2-1.2
Bone: trabecular number0.30.51.3-1.0-0.5-0.5-0.5-0.80.4-0.8-1.1-0.1-1.0-1.0-0.80.00.8-1.1-0.2-0.20.2
Bone: trabecular spacing0.30.30.90.60.40.40.10.60.40.61.0-0.70.80.80.70.30.20.8-0.20.2-0.2
Bone: trabecular thickness0.60.72.7-1.1-0.5-0.7-0.2-1.1-0.2-1.1-1.10.3-1.2-1.0-0.6-0.50.2-1.60.4-0.60.6
Bone: trabecular tissue density0.30.43.00.6-0.10.2-0.40.60.30.70.6-1.70.90.60.20.1-0.40.60.10.4-0.4
Water consumed over 24 hours0.30.41.4-0.5-0.8-0.4-1.2-0.20.2-0.1-0.8-1.0-0.6-0.8-1.1-0.00.2-0.30.10.1-0.1
Number of responses in last shaping day1.71.72.81.71.51.51.51.60.81.51.40.71.61.41.51.10.31.2-1.01.3-1.3