Pes1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Pes1 0.04 0.03 6.0e-05 0.03 0.04 0.03 0.03 5.2e-04 4.3e-05 1.1e-04 2.0e-04
2 pVTA mRNA stability Pes1 0.04 0.02 7.8e-04 0.03 0.04 0.05 0.05 1.0e-03 2.3e-04 7.2e-05 1.1e-04
3 IL mRNA stability Pes1 0.21 0.1 3.8e-04 0.1 0.12 0.09 0.11 2.8e-03 9.1e-04 3.6e-03 1.6e-03
4 NAcc intron excision ratio chr14_83079752_83080593 0.02 0.01 2.5e-03 0.01 0.02 0.01 0.01 2.3e-03 1.6e-03 6.2e-03 1.9e-03
5 Brain mRNA stability Pes1 0.21 0.07 0.0e+00 0.28 0.3 0.3 0.31 1.2e-26 1.6e-28 1.9e-28 6.0e-29
6 OFC gene expression Pes1 0.19 0.11 2.8e-03 0.09 0.11 0.03 0.1 4.0e-03 1.6e-03 8.3e-02 2.0e-03
7 Liver mRNA stability Pes1 0.05 0.03 1.4e-05 0.05 0.03 0.04 0.04 2.0e-06 6.6e-04 2.0e-05 1.1e-05
8 PL mRNA stability Pes1 0.09 0.04 3.3e-11 0.11 0.1 0.1 0.11 6.9e-12 1.5e-11 2.4e-11 9.5e-12
9 NAcc mRNA stability Pes1 0.05 0.02 6.0e-07 0.04 0.03 0.04 0.04 4.9e-07 1.1e-05 7.3e-07 2.6e-06
10 PL intron excision ratio chr14_83079752_83080593 0.05 0.02 3.0e-06 0.08 0.05 0.08 0.08 2.3e-09 1.6e-06 5.8e-09 7.3e-09
11 pVTA gene expression Pes1 0.07 0.04 1.1e-05 0.07 0.05 0.05 0.06 4.6e-06 1.0e-04 6.3e-05 1.2e-05
12 pVTA intron excision ratio chr14_83079752_83080593 0.03 0.02 5.3e-03 0.02 0.02 0.02 0.02 9.0e-03 1.4e-02 6.1e-03 9.7e-03
13 Brain intron excision ratio chr14_83074383_83079673 0.03 0.02 8.6e-03 0.01 0.02 0.02 0.01 3.0e-02 5.8e-03 2.6e-03 2.0e-02
14 Adipose mRNA stability Pes1 0.13 0.06 2.9e-15 0.13 0.13 0.13 0.13 6.2e-14 2.1e-14 7.2e-14 1.9e-14
15 BLA mRNA stability Pes1 0.05 0.03 6.5e-03 0.02 0.03 0.04 0.02 3.0e-02 8.8e-03 3.4e-03 2.0e-02
16 Adipose gene expression Pes1 0.04 0.03 9.6e-03 -0 0 -0 -0 8.1e-01 1.6e-01 5.4e-01 7.9e-01
17 NAcc gene expression Pes1 0.05 0.03 6.3e-04 0 0 0.01 0 4.4e-02 2.5e-01 1.8e-02 2.4e-01
18 LHb mRNA stability Pes1 0.17 0.1 8.1e-03 0.18 0.02 0.05 0.13 4.4e-05 8.7e-02 2.6e-02 4.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.61.04.3-0.81.5-0.6-1.2-0.7-0.41.2-0.10.81.2-0.11.01.6-0.70.2-2.10.01.1
Area under the delay curve6.39.715.02.9-3.23.23.43.23.0-2.8-2.5-3.5-3.6-2.3-3.9-2.13.3-3.32.8-2.6-3.9
BMI with tail0.93.09.82.0-2.11.82.21.01.6-1.3-0.4-1.8-1.9-0.7-1.9-1.71.5-1.53.1-0.5-2.1
BMI without tail0.21.14.01.9-1.41.41.40.51.1-0.6-0.4-0.8-0.8-0.6-0.8-0.80.2-0.52.00.4-0.9
Body weight3.013.321.74.7-4.54.44.53.54.0-2.9-3.0-3.7-3.5-3.1-3.7-2.93.1-3.24.0-2.6-3.5
Weight adjusted by age0.82.43.71.9-1.91.81.81.51.6-1.1-1.2-1.7-1.7-1.0-1.8-1.51.3-1.41.4-1.0-1.8
Bone surface0.10.10.30.30.00.40.20.50.4-0.2-0.5-0.5-0.2-0.4-0.20.10.4-0.5-0.1-0.3-0.2
Bone volume0.10.10.60.00.60.1-0.20.10.20.2-0.5-0.00.4-0.40.30.7-0.0-0.2-0.8-0.30.4
Breakpoint value in progressive ratio session0.10.20.80.40.10.40.40.30.6-0.1-0.4-0.5-0.5-0.4-0.50.10.5-0.50.1-0.9-0.5
Number of licking bursts0.51.43.21.7-1.01.41.11.11.3-1.3-1.8-0.4-0.3-1.7-1.10.20.2-1.40.0-1.2-1.5
Context. condit. distance diff. score1.82.24.8-1.51.6-1.5-1.7-1.9-1.42.21.41.61.41.51.31.2-1.41.2-1.01.50.9
Locomotion velocity, session 10.80.93.0-1.70.4-1.5-0.7-0.6-1.40.31.60.20.11.70.4-0.8-0.11.00.40.70.2
Locomotion distance, session 10.91.23.5-1.31.4-1.1-1.4-1.2-1.01.90.80.80.80.80.81.1-0.90.5-1.21.20.5
Locomotion velocity, session 21.72.07.4-2.71.2-2.3-1.6-1.0-2.10.31.60.80.91.51.3-0.3-0.41.5-1.20.21.4
Locomotion distance, session 22.73.87.6-2.82.2-2.5-2.3-2.1-2.41.82.41.61.62.41.81.0-1.11.7-0.82.01.3
Locomotion velocity, session 30.50.51.6-0.90.8-0.8-0.9-0.9-0.71.30.80.60.50.70.40.7-0.40.2-0.60.9-0.0
Locomotion distance, session 30.50.51.5-0.0-0.90.10.60.70.0-0.80.3-1.0-0.90.5-0.8-1.10.9-0.31.20.0-1.0
Stereotopy head waving bouts, day 31.31.52.3-1.41.0-1.4-1.5-1.3-1.31.50.71.11.30.91.50.8-1.21.1-1.31.01.4
Stereotopy head waving duration, day 32.32.84.7-1.81.5-1.8-1.9-2.0-1.72.21.51.51.81.51.91.1-1.81.6-1.11.91.6
Locomotion velocity, session 70.20.21.9-0.4-0.5-0.30.10.1-0.3-0.10.6-0.2-0.30.5-0.2-1.40.70.40.3-0.2-0.1
Locomotion distance, session 70.40.61.7-1.30.6-1.0-0.9-0.8-0.90.81.10.40.41.20.40.1-0.00.6-0.20.70.1
Stereotopy head waving bouts, day 70.40.41.00.8-1.00.80.80.60.7-0.5-0.5-0.7-0.5-0.3-0.6-0.30.5-0.60.9-0.2-0.8
Stereotopy head waving duration, day 70.30.41.01.0-1.00.90.80.60.8-0.3-0.6-0.6-0.4-0.4-0.6-0.10.3-0.60.90.0-0.7
Locomotion velocity, session 83.23.97.0-2.62.1-2.6-2.2-1.9-2.41.22.01.82.12.22.20.8-1.52.3-1.21.42.0
Locomotion distance, session 87.310.514.9-3.53.5-3.5-3.7-3.8-3.33.93.13.43.33.13.32.4-3.03.0-2.23.32.7
Degree of sensitization distance4.44.76.7-2.22.4-2.2-2.5-2.5-2.02.61.62.52.41.52.41.7-2.12.0-2.11.52.3
Degree of sensitization stereotypy0.70.81.71.3-1.11.21.10.91.1-0.8-0.9-0.7-0.7-0.7-0.8-0.20.6-0.81.0-0.4-0.8
Conditioned locomotion0.20.31.90.10.70.2-0.4-0.40.31.00.10.20.3-0.1-0.11.4-0.1-0.6-0.40.3-0.4
Cocaine response after cond. corrected0.81.21.90.8-1.11.11.01.31.2-1.0-1.2-1.3-1.2-1.3-1.1-0.41.1-1.30.1-1.4-0.9
Cocaine response after cond. not corrected2.23.25.51.7-1.81.91.72.02.0-1.4-2.2-1.8-1.8-2.4-1.8-0.61.6-2.10.2-2.2-1.4
Cocaine response before conditioning0.30.30.70.7-0.60.60.60.40.7-0.0-0.7-0.3-0.7-0.8-0.7-0.50.4-0.5-0.0-0.6-0.5
Saline control response0.91.23.6-1.60.9-1.4-1.0-1.2-1.41.21.90.50.41.70.4-0.6-0.31.00.11.40.0
Bone: connectivity density0.30.41.7-0.60.9-0.4-0.8-0.5-0.21.10.00.40.60.10.41.1-0.4-0.0-1.30.20.3
Bone: cortical apparent density0.10.20.50.70.30.60.40.30.5-0.4-0.50.0-0.2-0.2-0.40.70.0-0.70.6-0.1-0.5
Bone: cortical area3.04.99.73.1-2.72.72.82.12.5-1.6-2.2-1.9-2.1-2.3-2.2-2.01.6-1.92.0-1.5-1.8
Bone: cortical porosity0.40.51.00.4-0.90.60.50.80.7-0.7-0.8-0.6-0.7-0.8-0.6-0.30.8-0.6-0.4-1.0-0.4
Bone: cortical porosity0.20.20.50.4-0.70.50.20.50.5-0.4-0.6-0.2-0.4-0.6-0.3-0.00.4-0.4-0.3-0.5-0.1
Bone: cortical thickness2.84.710.53.2-2.52.92.62.12.7-1.4-2.3-1.7-1.9-2.4-2.2-1.31.5-2.11.8-1.3-1.9
Bone: cortical thickness0.30.42.00.70.20.6-0.1-0.30.61.0-0.10.4-0.0-0.3-0.41.4-0.6-0.8-0.10.9-0.8
Bone: cortical tissue density0.10.20.50.70.20.60.40.30.5-0.5-0.5-0.1-0.2-0.3-0.40.60.1-0.70.7-0.1-0.6
Condit. Reinf. active minus inactive responses0.30.41.2-0.8-0.2-0.50.10.1-0.5-0.10.7-0.8-0.51.1-0.4-1.00.80.21.00.2-0.6
Condit. Reinf. active-inactive response ratio1.41.55.8-2.00.5-1.7-0.8-0.8-1.70.12.1-0.00.22.40.5-0.90.11.41.01.20.2
Condit. Reinf. active responses0.10.20.6-0.6-0.1-0.5-0.1-0.1-0.50.20.6-0.3-0.10.8-0.0-0.60.30.30.70.5-0.2
Condit. Reinf. inactive responses0.40.52.11.2-0.40.90.60.40.90.1-1.20.1-0.1-1.5-0.30.2-0.1-0.7-0.3-0.5-0.1
Incentive salience index mean0.60.82.10.1-0.90.30.80.80.2-0.60.1-1.2-1.20.3-1.0-1.41.3-0.41.4-0.3-1.2
Condit. Reinf. lever presses0.81.22.11.1-1.11.11.31.01.0-0.6-0.6-1.1-1.4-0.7-1.4-1.01.1-1.11.4-0.6-1.5
Condit. Reinf. active minus inactive responses0.50.81.9-0.70.6-0.9-0.8-1.2-1.01.40.90.90.60.90.7-0.1-0.91.1-0.51.30.5
Condit. Reinf. active-inactive response ratio0.10.10.8-0.2-0.0-0.10.1-0.1-0.10.30.3-0.3-0.60.4-0.6-0.30.4-0.20.40.3-0.9
Condit. Reinf. active responses1.62.34.0-1.81.4-1.9-1.6-1.9-1.92.01.81.41.11.91.1-0.0-1.01.7-0.81.80.7
Condit. Reinf. inactive responses1.92.94.0-1.91.6-2.0-1.8-1.9-2.01.81.81.71.71.91.70.4-1.42.0-1.01.71.5
Condit. Reinf. lever presses0.30.41.2-0.50.4-0.6-0.5-0.9-0.71.01.00.60.30.90.3-0.5-0.20.70.21.1-0.0
Condit. Reinf. lever reinforcers received1.11.63.3-1.61.0-1.5-1.3-1.6-1.51.81.71.00.71.70.7-0.3-0.61.3-0.41.70.3
Conditioned reinforcement - actives0.52.13.01.4-1.71.51.71.71.5-1.6-1.5-1.6-1.6-1.2-1.3-1.01.6-1.21.2-1.6-0.8
Conditioned reinforcement - inactives1.43.96.51.6-2.51.82.32.31.6-2.4-1.3-2.4-2.4-1.0-1.9-2.42.3-1.32.0-1.6-1.4
Conditioned locomotion1.32.03.21.5-1.61.51.51.71.5-1.8-1.6-1.5-1.2-1.6-1.1-0.91.2-1.20.5-1.7-0.6
Patch foraging indifference point 0 sec0.00.10.40.6-0.20.40.30.20.3-0.2-0.6-0.00.1-0.5-0.2-0.1-0.0-0.30.2-0.2-0.4
Patch foraging indifference point AUC0.41.03.0-1.50.6-1.3-0.8-1.0-1.40.51.70.30.31.70.4-1.1-0.21.3-0.00.90.2
Delay disc. indifference point, 0s delay7.58.511.53.0-2.83.33.03.03.3-2.6-2.7-3.3-3.2-2.4-3.4-0.63.2-3.22.5-2.4-3.2
Delay disc. indifference point, 16s delay3.34.78.71.6-2.11.82.22.21.8-2.2-1.7-2.4-2.5-1.4-2.8-1.62.5-2.41.8-2.4-3.0
Delay disc. indifference point, 2s delay7.38.111.03.0-3.13.23.03.13.1-2.4-2.7-3.2-3.2-2.4-3.3-1.42.8-3.02.1-2.2-3.0
Delay disc. indifference point, 24s delay3.45.512.41.7-2.22.12.22.52.2-2.0-1.7-2.5-2.8-1.6-3.2-0.82.6-3.01.8-2.1-3.5
Delay disc. indifference point, 4s delay5.25.57.92.2-2.62.42.52.62.3-2.1-1.9-2.6-2.8-2.0-2.8-1.92.5-2.41.8-1.9-2.6
Delay disc. indifference point, 8s delay1.01.83.51.2-1.51.21.61.11.0-1.3-0.5-1.6-1.6-0.7-1.6-1.71.3-1.01.9-0.6-1.6
Indifference point function ln k0.20.51.90.40.10.5-0.00.20.70.4-1.20.10.2-1.40.10.70.1-0.7-1.3-0.90.3
Indifference point function log k0.20.51.90.40.10.5-0.00.20.70.4-1.20.10.2-1.40.10.70.1-0.7-1.3-0.90.3
Patch foraging total patch changes 0 sec0.00.10.30.6-0.40.40.40.20.2-0.4-0.4-0.1-0.1-0.4-0.3-0.40.0-0.20.4-0.1-0.4
Patch foraging total patch changes 12 sec0.10.10.50.7-0.40.50.5-0.00.5-0.2-0.4-0.0-0.2-0.4-0.3-0.1-0.0-0.20.4-0.1-0.4
Patch foraging total patch changes 18 sec0.20.42.1-0.2-0.6-0.20.50.3-0.4-1.00.6-0.5-0.40.8-0.2-1.40.30.71.30.2-0.2
Patch foraging total patch changes 24 sec0.93.07.1-1.61.6-1.8-1.6-2.2-1.91.82.31.71.62.31.40.7-1.71.60.22.70.6
Patch foraging total patch changes 6 sec0.10.11.7-0.0-0.3-0.10.20.1-0.2-0.20.3-0.2-0.20.2-0.3-1.30.30.30.2-0.2-0.4
Patch foraging time to switch 0 sec0.20.64.61.20.10.80.20.20.7-0.2-0.70.70.8-0.50.62.1-0.8-0.20.60.50.7
Patch foraging water rate 0 sec0.20.98.90.2-1.30.10.90.4-0.0-0.60.2-0.9-1.0-0.3-0.7-3.00.60.20.6-0.6-0.5
Patch foraging water rate 12 sec0.10.43.2-0.3-0.6-0.30.1-0.3-0.50.40.5-0.2-0.20.60.3-1.8-0.11.10.20.60.6
Patch foraging water rate 18 sec0.40.82.70.50.50.0-0.6-0.8-0.01.6-0.41.21.1-0.90.80.6-1.50.3-1.60.80.9
Patch foraging water rate 24 sec0.60.83.5-0.1-0.5-0.60.0-0.3-0.80.40.70.70.30.51.0-1.8-0.91.90.20.81.6
Patch foraging water rate 6 sec0.20.42.50.4-0.80.10.3-0.0-0.10.3-0.10.2-0.0-0.10.5-1.6-0.51.1-0.10.41.0
Seeking ratio, delayed vs. immediate footshock0.40.62.1-1.41.2-1.2-0.9-0.7-1.1-0.40.60.30.10.50.3-0.3-0.10.4-1.3-0.30.4
Distance traveled before self-admin0.10.20.9-0.70.9-0.5-0.7-0.3-0.50.30.60.10.10.10.30.4-0.00.1-0.90.00.3
Distance traveled after self-admin0.10.10.40.20.20.4-0.10.30.4-0.2-0.3-0.5-0.5-0.5-0.40.50.5-0.6-0.4-0.3-0.3
Extensor digitorum longus weight2.711.017.34.0-4.23.83.93.63.5-2.8-3.6-3.3-3.3-3.4-3.2-3.02.7-2.72.3-3.0-2.5
Bone: elastic displacement0.30.30.90.50.50.2-0.2-0.30.10.5-0.50.61.0-0.30.70.9-0.90.3-0.70.30.7
Bone: elastic work0.50.73.01.7-0.61.20.70.41.10.2-1.60.10.4-1.40.20.4-0.8-0.3-0.4-0.20.4
Bone: endosteal estimation0.00.10.50.1-0.2-0.1-0.1-0.2-0.20.20.00.40.4-0.20.5-0.4-0.50.6-0.30.10.7
Bone: endosteal perimeter0.30.72.20.9-1.10.81.10.90.6-0.7-0.6-0.9-0.9-0.7-0.8-1.50.7-0.40.7-0.8-0.6
Epididymis fat weight0.83.98.12.8-2.02.72.32.02.6-1.2-2.3-1.6-1.4-2.3-1.8-0.41.6-2.11.5-2.0-1.6
Delta time in closed arm before/after self-admin2.32.25.5-1.32.2-1.2-1.8-2.0-0.82.20.61.51.30.91.02.3-1.30.5-1.80.80.6
Delta time in open arm before/after self-admin3.33.98.21.8-2.61.72.42.41.4-2.9-0.8-1.9-2.1-0.8-1.9-2.32.1-1.12.7-1.2-1.6
Diff in mean of infusions in LGA sessions0.10.20.7-0.40.6-0.2-0.3-0.2-0.20.00.8-0.00.00.5-0.10.70.2-0.30.30.5-0.5
Delay discount exponential model param6.89.314.2-2.83.2-3.1-3.3-3.1-2.92.72.43.43.52.23.82.2-3.23.2-2.82.53.8
Extinction: sum of active levers before priming0.91.34.20.2-0.60.60.81.00.7-1.1-0.3-1.5-1.5-0.6-1.7-0.61.5-1.60.9-1.4-2.1
Active lever presses in extinction session 61.01.02.30.9-0.61.20.81.11.3-1.0-1.3-1.2-0.9-1.2-0.80.51.3-1.10.0-1.5-0.3
Bone: final force0.30.41.91.4-1.10.90.90.30.6-0.4-0.3-0.1-0.2-0.6-0.2-0.7-0.3-0.01.20.4-0.1
Bone: final moment0.30.52.11.5-1.11.00.90.50.7-0.5-0.7-0.0-0.1-0.9-0.1-0.6-0.2-0.10.80.10.1
Food consumed during 24 hour testing period0.20.53.0-0.8-0.2-0.9-0.0-0.3-1.0-0.21.10.30.11.0-0.1-1.7-0.00.80.50.1-0.5
Glucose6.810.737.60.0-3.90.63.23.90.3-4.90.3-4.0-3.90.4-2.9-6.14.1-0.54.5-2.8-2.4
Heart weight0.40.71.30.5-1.00.61.00.80.6-1.0-0.2-0.8-1.0-0.5-1.0-1.10.8-0.60.9-0.9-0.8
Delay discount hyperbolic model param7.59.714.4-3.03.3-3.2-3.4-3.2-3.02.82.43.53.62.33.82.2-3.23.2-2.92.53.7
Intermittent access intake day 1-15 change0.10.72.00.2-1.10.40.90.90.4-1.4-0.0-1.1-1.1-0.1-0.3-1.31.10.11.1-0.90.4
Intermittent access intake escalation0.21.12.10.4-1.30.71.11.10.7-1.5-0.5-1.4-1.4-0.5-0.8-1.41.4-0.41.0-1.3-0.1
Intermittent access intake escalation 20.20.31.10.4-0.70.30.50.60.3-1.1-0.3-0.4-0.4-0.50.1-0.70.30.20.4-0.50.7
Intermitt. access day 1 inactive lever presses0.00.61.20.4-0.70.60.70.60.7-0.0-0.3-1.0-1.1-0.2-1.0-1.11.0-0.70.3-0.8-0.9
Intermitt. access day 15 inactive lever presses0.42.110.00.4-1.60.41.51.00.2-1.20.8-1.4-1.80.5-1.7-3.21.4-0.22.2-0.3-2.0
Intermitt. access escalation Index0.20.72.0-1.00.6-1.0-0.7-1.0-1.01.21.20.60.71.40.20.2-0.70.40.61.0-0.6
Intermittent access day 1 total infusions0.82.34.11.7-1.31.81.61.81.7-2.0-1.7-1.6-1.5-1.4-1.5-0.31.6-1.51.1-1.2-1.1
Intermittent access day 15 total infusions1.53.87.21.7-2.41.92.22.31.8-2.7-1.7-2.3-2.3-1.5-1.7-1.62.3-1.21.6-2.0-0.8
Intermittent access terminal intake (last 3 days)1.22.24.91.4-1.81.51.61.81.4-2.2-1.5-1.8-1.7-1.2-1.0-1.31.6-0.71.1-1.6-0.1
Intermittent access total infusions2.22.75.01.5-1.91.61.72.11.6-2.2-1.9-2.0-1.8-1.4-1.2-1.21.9-1.00.9-1.9-0.3
Intermittent access day 1 locomotion0.10.10.3-0.40.5-0.3-0.5-0.1-0.3-0.20.20.10.30.20.30.4-0.10.0-0.60.20.3
Intermittent access day 15 total locomotion1.14.36.72.3-2.32.32.52.32.2-2.6-1.7-2.2-2.1-1.7-2.1-1.52.0-1.72.0-1.8-1.7
Intermittent access total locomotion1.61.93.31.0-1.61.21.41.71.2-1.7-1.2-1.8-1.6-0.9-1.4-1.51.7-1.00.8-1.6-1.0
Intermittent access standard deviation0.00.10.50.4-0.50.30.30.40.2-0.5-0.1-0.4-0.3-0.10.1-0.70.30.20.30.20.6
Left kidney weight0.21.87.42.7-1.52.21.40.62.10.2-2.0-0.5-0.2-2.2-0.6-0.2-0.0-0.9-0.0-0.8-0.2
Right kidney weight0.43.111.03.3-1.32.81.50.82.80.5-2.8-0.7-0.4-2.9-1.01.00.2-2.1-0.3-1.0-0.8
Cocaine induced anxiety0.61.74.80.7-1.50.81.41.30.7-1.5-0.3-1.4-1.6-0.8-1.6-2.21.5-1.01.1-1.2-1.5
Post-drug Anxiety2.22.54.31.1-1.51.31.61.61.3-1.9-0.8-1.8-1.9-1.2-2.0-1.41.8-1.71.6-1.5-2.1
Baseline Anxiety0.20.31.80.5-0.10.60.30.50.7-0.4-0.6-0.4-0.3-0.4-0.31.30.4-0.80.6-0.4-0.2
Tail length0.63.57.12.7-2.32.42.22.32.1-1.6-2.5-1.6-1.3-2.6-1.3-1.51.1-1.20.3-1.8-0.6
Length with tail1.56.613.83.7-3.23.33.02.93.1-1.8-3.3-2.1-2.0-3.4-2.1-1.81.6-2.00.9-2.6-1.3
Length without tail0.84.07.12.6-2.22.52.22.12.5-1.3-2.7-1.7-1.6-2.4-1.9-0.71.6-2.10.8-2.4-1.5
Times rat made contact with spout1.21.44.0-2.00.9-1.9-0.9-0.9-1.9-0.22.00.60.41.90.3-1.1-0.11.10.20.6-0.5
Lifetime Intake1.92.34.31.3-1.61.51.62.01.5-2.1-1.8-1.8-1.7-1.5-1.1-1.11.8-0.90.6-1.9-0.2
Liver weight, left0.10.21.20.30.40.3-0.3-0.60.31.1-0.40.30.4-0.50.20.5-0.4-0.1-0.90.10.2
Liver weight, right0.30.51.50.40.4-0.0-0.4-0.9-0.11.20.50.90.9-0.00.70.5-1.00.5-0.21.20.6
Locomotor activity0.30.52.9-0.6-0.7-0.60.20.7-0.7-1.10.3-0.2-0.30.70.4-1.70.31.20.4-0.21.0
Locomotor testing distance0.41.12.21.3-1.41.21.21.21.1-1.1-1.5-0.9-0.9-1.2-0.5-1.01.0-0.50.4-1.00.1
Locomotor testing rearing0.62.14.11.2-1.81.21.61.81.1-1.9-1.3-1.6-1.5-1.3-1.1-2.01.5-0.90.9-1.5-0.6
Locomotion in novel chamber0.20.31.3-0.10.4-0.1-0.6-0.60.00.90.10.50.5-0.10.11.1-0.5-0.3-0.80.4-0.2
Locomotion in novel chamber post-restriction0.82.35.0-2.21.6-2.0-1.7-1.8-1.91.32.21.21.12.11.20.6-0.91.1-0.21.60.6
Fecal boli incidents, locomotor time 10.20.51.3-1.10.4-1.0-0.9-0.7-0.90.70.70.50.50.70.7-0.3-0.40.9-0.90.20.7
Change in fecal boli incidents, locomotor task0.91.02.9-1.40.8-1.4-0.8-0.8-1.40.11.70.70.71.40.8-0.2-0.61.20.11.00.5
Time >=10cm from walls, locomotor time 10.30.32.00.60.20.40.1-0.20.50.00.10.50.6-0.30.71.4-0.2-0.20.70.40.9
Bouts of movement, locomotor time 10.20.21.0-0.1-0.50.10.30.40.1-0.30.0-0.5-0.30.3-0.60.10.5-0.51.0-0.2-1.0
Total resting periods, locomotor time 10.30.41.7-0.2-0.60.00.40.60.1-0.40.3-0.7-0.50.7-0.7-0.30.7-0.51.3-0.1-1.2
Rest time, locomotor task time 10.20.31.1-0.7-0.3-0.7-0.2-0.0-0.80.10.90.00.01.0-0.3-1.0-0.10.00.40.5-1.0
Distance moved, locomotor task time 10.10.31.30.70.20.40.0-0.30.3-0.1-0.70.50.3-0.60.61.0-0.60.4-0.50.01.2
Vertical activity count, locomotor time 10.10.72.4-0.51.2-0.5-0.8-0.7-0.50.10.20.90.60.11.11.3-0.80.9-1.00.21.5
Time >=10cm from walls, locomotor time 20.10.30.6-0.60.8-0.6-0.6-0.8-0.50.30.50.60.40.10.60.7-0.40.2-0.20.30.7
Bouts of movement, locomotor time 20.10.30.70.4-0.40.60.60.20.60.1-0.4-0.9-0.70.0-0.6-0.60.8-0.40.6-0.3-0.4
Total resting periods, locomotor time 20.10.41.00.3-0.40.50.60.20.50.1-0.2-1.0-0.90.3-0.8-0.90.9-0.40.9-0.2-0.8
Rest time, locomotor task time 20.30.61.3-0.90.4-1.0-0.7-0.7-1.00.81.00.70.61.10.5-0.1-0.60.7-0.01.0-0.0
Distance moved, locomotor task time 20.10.21.10.30.20.2-0.1-0.40.2-0.0-0.40.30.4-0.50.31.0-0.6-0.0-0.3-0.00.4
Vertical activity count, locomotor time 20.10.10.7-0.00.20.2-0.10.10.3-0.3-0.4-0.2-0.2-0.5-0.20.80.1-0.4-0.7-0.7-0.0
Light reinforcement 10.20.92.21.5-1.41.31.20.81.2-0.1-1.2-0.9-0.6-1.3-0.7-0.80.2-0.80.8-0.2-0.5
Light reinforcement 20.10.31.31.1-0.50.70.4-0.10.40.3-0.70.30.4-0.50.4-0.0-0.70.30.20.50.6
Bone: marrow area0.00.10.40.0-0.1-0.2-0.1-0.3-0.20.30.10.40.3-0.10.5-0.3-0.50.6-0.20.10.6
Bone: maximum diameter2.65.29.92.5-2.92.33.02.32.0-2.3-1.7-2.2-2.4-1.8-2.2-3.11.9-1.42.6-1.8-1.7
Bone: maximum force0.20.31.81.3-0.70.80.70.20.6-0.0-0.60.10.1-0.60.0-0.4-0.50.10.70.40.1
Bone: maximum moment0.20.41.91.4-0.80.90.70.30.7-0.1-0.90.20.1-0.90.1-0.4-0.50.00.20.00.3
Mean time between licks in bursts0.21.13.4-1.80.7-1.7-1.0-0.7-1.70.31.50.50.81.40.5-0.6-0.80.9-0.60.6-0.0
Mean num. licks in bursts1.23.38.9-2.91.6-2.5-1.7-1.6-2.51.13.00.80.62.81.2-0.8-0.32.00.11.61.1
Cd content in liver0.10.10.5-0.0-0.50.00.40.5-0.1-0.60.1-0.4-0.20.1-0.1-0.40.00.20.7-0.0-0.0
Co content in liver0.80.91.70.9-1.31.01.01.01.0-0.4-0.8-1.1-1.0-0.8-1.1-0.91.2-0.90.5-1.0-1.0
Cu content in liver0.20.20.7-0.1-0.00.20.10.30.40.2-0.4-0.6-0.5-0.4-0.60.40.6-0.9-0.0-0.7-0.7
Fe content in liver0.91.23.8-1.90.9-1.5-1.4-1.1-1.31.11.60.50.51.70.50.4-0.10.6-0.50.90.1
K content in liver5.25.19.22.2-1.82.52.02.42.7-1.2-2.8-2.3-2.1-2.7-2.5-0.22.3-3.00.4-2.7-2.3
Mg content in liver4.44.96.72.3-2.22.52.32.32.6-1.5-2.4-2.2-2.2-2.4-2.4-0.92.2-2.61.2-2.5-2.2
Mn content in liver0.10.20.60.1-0.10.20.10.50.3-0.2-0.5-0.4-0.4-0.6-0.3-0.00.6-0.4-0.6-0.8-0.1
Na content in liver4.34.88.91.0-2.21.62.12.41.7-2.4-1.1-2.8-2.8-1.2-2.7-2.03.0-2.41.8-2.3-2.6
Rb content in liver0.70.81.31.1-1.11.11.01.01.0-0.6-1.1-0.9-0.9-0.6-1.1-0.30.8-0.90.8-0.9-1.0
Se content in liver3.13.76.91.9-1.52.11.82.12.2-1.0-2.4-1.9-1.9-2.5-2.1-0.61.9-2.20.1-2.6-1.7
Sr content in liver1.61.43.11.2-1.61.01.61.30.8-1.7-0.7-1.2-1.2-0.7-1.0-1.81.0-0.41.6-1.0-0.6
Zn content in liver0.20.21.10.7-0.30.60.50.40.60.1-0.8-0.20.0-1.10.0-0.3-0.1-0.2-0.4-0.50.4
Bone: minimum diameter0.10.10.40.4-0.10.10.0-0.30.10.6-0.20.40.3-0.20.4-0.3-0.50.5-0.30.20.6
Time in familiar zone, hab. session 11.51.62.6-1.01.1-1.2-1.3-1.3-1.30.71.21.41.51.41.61.0-1.41.5-0.51.61.4
Time in novel zone, hab. session 11.11.22.51.1-0.81.21.11.11.2-0.7-1.4-1.0-1.1-1.6-1.1-0.70.9-1.2-0.1-1.5-0.8
Total zone transitions, hab. session 10.91.32.8-1.60.9-1.5-1.1-1.0-1.60.51.70.70.81.71.0-0.1-0.61.3-0.01.50.7
Total locomotion distance, hab. session 10.20.21.1-1.00.4-0.8-0.5-0.1-0.7-0.00.6-0.10.00.70.2-0.40.20.4-0.20.20.1
Locomotion velocity, hab. session 10.20.31.4-1.20.3-0.9-0.5-0.2-0.80.20.8-0.10.00.90.2-0.40.20.40.10.50.1
Time in familiar zone, hab. session 22.73.15.8-1.52.3-1.6-2.0-2.0-1.41.71.52.01.91.31.82.4-1.91.2-1.41.71.4
Time in novel zone, hab. session 22.02.26.21.7-2.11.41.91.61.2-1.4-1.3-1.4-1.4-1.1-1.2-2.51.2-0.61.5-1.2-0.8
Total zone transitions, hab. session 20.20.31.2-0.4-0.3-0.40.10.1-0.5-0.00.7-0.5-0.20.70.0-1.10.20.50.90.60.0
Total locomotion distance, hab. session 20.30.32.3-0.2-0.6-0.20.50.4-0.4-0.60.4-0.6-0.30.5-0.1-1.50.40.51.10.10.1
Locomotion velocity, hab. session 20.30.52.30.0-0.90.10.70.7-0.0-0.80.1-0.9-0.70.2-0.5-1.50.70.01.2-0.2-0.3
Novel to familiar place preference ratio1.31.73.70.1-1.20.51.21.20.4-1.5-0.0-1.7-1.80.2-1.7-1.91.9-0.81.8-0.7-1.8
Novelty place preference1.31.63.70.2-1.20.51.21.20.4-1.4-0.1-1.6-1.80.1-1.6-1.91.8-0.81.7-0.8-1.7
Time in novel zone, NPP test1.11.43.70.1-1.10.41.11.00.3-1.30.0-1.5-1.70.2-1.5-1.91.6-0.61.6-0.7-1.6
Total zone transitions, NPP test0.10.10.8-0.10.20.0-0.2-0.10.10.9-0.3-0.00.0-0.0-0.20.40.1-0.4-0.30.2-0.3
Total locomotion distance, NPP test0.10.10.4-0.0-0.00.10.10.30.20.2-0.4-0.4-0.3-0.1-0.50.00.7-0.60.0-0.3-0.6
Locomotion velocity, NPP test0.20.31.00.1-0.30.40.30.60.5-0.1-0.7-0.7-0.6-0.3-0.80.11.0-1.00.1-0.6-0.9
Intraocular pressure0.71.13.3-0.6-0.4-0.80.0-0.3-1.1-0.61.80.10.41.80.7-1.6-0.01.51.71.30.5
Delta distance traveled before/after self-admin0.40.50.80.9-0.70.90.70.80.9-0.7-0.9-0.6-0.6-0.6-0.60.30.6-0.80.6-0.3-0.5
Delta ambulatory time before/after self-admin0.10.10.70.2-0.00.30.00.30.4-0.1-0.5-0.1-0.1-0.4-0.20.90.2-0.7-0.1-0.2-0.3
Parametrial fat weight1.43.214.1-0.8-1.6-0.51.21.2-0.9-2.31.9-1.9-1.62.2-1.1-3.21.80.73.80.2-1.5
Pavlov. Cond. lever latency0.10.10.3-0.3-0.3-0.10.00.3-0.0-0.4-0.1-0.4-0.2-0.3-0.1-0.20.1-0.1-0.4-0.50.1
Pavlov. Cond. magazine entry latency1.41.92.9-1.51.7-1.5-1.5-1.5-1.61.21.41.41.11.71.20.7-1.21.5-0.71.61.0
Pavlov. Cond. change in total contacts0.50.61.70.2-0.50.30.70.80.2-1.20.1-0.9-0.90.3-0.8-0.91.1-0.41.3-0.2-1.0
Pavlov. Cond. index score0.70.92.0-0.91.4-1.0-1.1-1.1-1.01.11.01.00.81.20.70.9-0.70.8-0.41.30.4
Pavlov. Cond. latency score0.70.91.8-0.71.3-0.8-1.0-1.1-0.91.00.91.10.81.10.80.9-0.80.8-0.31.30.5
Pavlov. Cond. lever contacts0.20.30.8-0.20.7-0.3-0.4-0.7-0.30.70.50.60.50.60.40.5-0.30.40.10.90.2
Pavlov. Cond. magazine entry number1.31.64.01.8-1.51.61.41.31.6-1.0-1.7-1.0-0.7-2.0-0.9-0.30.7-1.30.4-1.5-0.6
Pavlov. Cond. intertrial magazine entries1.21.43.31.4-1.01.50.91.01.70.1-1.8-0.7-0.9-1.8-1.20.00.9-1.6-0.5-1.5-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.02.1-0.91.4-0.9-1.1-1.2-0.91.20.91.10.81.10.81.0-0.80.7-0.51.20.5
Pavlov. Cond. response bias0.10.20.5-0.60.7-0.5-0.5-0.4-0.40.50.40.30.10.70.10.3-0.00.3-0.20.4-0.0
Pavlov. Cond. lever latency2.53.57.92.4-1.82.41.82.22.4-1.5-2.8-1.7-1.2-2.6-1.40.30.9-2.10.1-2.0-1.0
Pavlov. Cond. magazine entry latency0.10.10.40.3-0.30.20.2-0.10.0-0.10.20.0-0.40.2-0.3-0.40.10.00.60.4-0.5
Pavlov. Cond. change in total contacts0.51.23.0-1.10.9-1.2-0.9-1.3-1.40.91.71.00.61.70.6-0.4-0.51.20.31.50.3
Pavlov. Cond. index score0.81.22.9-1.21.0-1.3-1.0-1.4-1.41.01.71.00.61.70.7-0.3-0.61.30.21.50.4
Pavlov. Cond. latency score0.81.32.9-1.21.1-1.3-1.1-1.5-1.41.11.71.20.61.60.8-0.1-0.71.30.01.50.4
Pavlov. Cond. lever contacts2.23.36.9-2.41.9-2.3-1.9-2.2-2.31.62.61.61.12.61.3-0.1-0.91.9-0.31.90.9
Pavlov. Cond. magazine entry number0.10.20.5-0.0-0.00.30.00.50.5-0.0-0.5-0.5-0.1-0.5-0.20.40.5-0.6-0.6-0.7-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.40.2-0.1-0.20.10.10.4-0.4-0.10.1-0.40.10.10.4-0.3-0.7-0.70.2
Pavlov. Cond. lever-magazine prob. diff.0.91.32.7-1.21.1-1.3-1.1-1.5-1.41.01.71.20.71.70.8-0.1-0.71.30.11.60.5
Pavlov. Cond. response bias1.11.63.5-1.61.2-1.6-1.2-1.6-1.60.91.91.20.81.90.9-0.1-0.61.40.11.40.5
Time in closed arm before self-admin0.30.51.70.40.2-0.0-0.4-0.7-0.11.0-0.11.01.1-0.60.70.6-1.30.3-0.90.70.5
Time in closed arm after self-admin1.61.85.5-0.51.5-0.7-1.4-1.8-0.42.30.01.71.7-0.11.12.0-1.80.3-2.00.80.6
Time in open arm before self-admin0.00.00.3-0.00.30.0-0.00.10.1-0.1-0.5-0.1-0.1-0.00.20.2-0.10.2-0.2-0.10.6
Time in open arm after self-admin1.11.24.50.5-1.30.51.21.20.3-1.80.2-1.1-1.30.4-0.7-1.81.20.22.1-0.2-0.3
Bone: periosteal estimation0.51.13.11.8-1.51.41.40.91.2-0.6-1.2-0.7-0.8-1.3-0.8-1.30.4-0.60.9-0.6-0.5
Bone: periosteal perimeter1.93.75.72.4-2.42.22.41.92.0-1.4-1.6-1.9-2.0-1.7-2.0-2.11.6-1.61.9-1.4-1.8
Bone: post-yield work0.10.20.4-0.40.4-0.4-0.4-0.2-0.4-0.2-0.10.50.30.20.50.1-0.30.6-0.6-0.20.6
Progressive ratio test 1 active lever presses1.32.24.00.8-1.31.21.31.71.3-1.6-1.4-1.9-1.9-1.2-1.7-1.02.0-1.60.6-1.9-1.4
Progressive ratio test 1 breakpoint1.42.34.20.8-1.31.31.41.71.4-1.6-1.5-2.0-2.0-1.3-1.8-1.02.0-1.60.6-1.9-1.5
Progressive ratio test 1 inactive lever presses1.53.96.51.3-2.21.62.12.11.4-2.5-1.1-2.5-2.5-1.0-2.3-2.42.4-1.41.8-1.8-2.1
Progressive ratio test 2 active lever presses1.21.85.21.2-1.51.31.51.71.2-2.3-1.2-1.5-1.4-0.9-1.1-1.01.5-0.81.3-1.3-0.6
Progressive ratio test 2 breakpoint1.21.64.71.1-1.41.21.41.61.1-2.2-1.1-1.4-1.3-0.8-1.0-0.91.4-0.71.3-1.2-0.5
Progressive ratio test 2 inactive lever presses1.44.48.82.0-2.71.92.62.21.6-3.0-1.2-2.3-2.2-0.9-2.0-2.42.0-1.23.0-1.2-1.7
Incentive Sensitization - Responses0.30.93.61.2-1.21.01.21.10.7-1.9-0.7-0.7-0.6-0.1-0.5-0.50.6-0.21.7-0.3-0.4
Incentive Sensitization - Breakpoint0.30.83.31.2-1.10.91.11.00.7-1.8-0.6-0.6-0.4-0.1-0.4-0.50.4-0.01.7-0.1-0.2
Sum of active levers in priming session hrs 5-61.21.12.31.00.01.20.91.01.3-0.9-1.2-1.2-1.1-1.3-1.10.51.1-1.50.3-1.4-0.8
Progressive ratio0.00.10.60.5-0.50.30.20.50.2-0.7-0.50.10.1-0.20.20.30.10.20.1-0.10.3
Food seeking constrained by brief footshock2.93.66.42.4-1.62.32.02.32.1-2.5-1.9-1.5-1.8-1.9-2.2-0.51.7-1.90.9-1.6-2.2
Seeking ratio, punishment vs. effort0.30.81.60.8-0.60.90.90.70.9-0.3-0.6-1.0-1.2-0.8-1.3-1.00.8-1.00.3-0.7-1.3
Retroperitoneal fat weight0.52.012.60.1-1.50.21.20.9-0.2-1.21.6-1.6-1.11.4-0.9-2.31.20.33.50.7-1.3
Reaction time number correct0.41.33.2-1.10.5-1.4-0.8-0.8-1.50.51.01.01.21.01.4-1.1-1.11.8-0.61.01.6
Reaction time mean minus median0.00.10.4-0.30.2-0.20.00.1-0.1-0.4-0.00.0-0.1-0.2-0.30.10.2-0.10.1-0.6-0.4
Reaction time mean minus median AUC0.10.50.70.8-0.70.70.80.70.7-0.7-0.8-0.6-0.7-0.7-0.7-0.30.6-0.60.8-0.7-0.6
Reaction time num false alarms0.91.52.81.7-1.21.71.31.01.6-0.9-1.2-1.1-1.3-1.0-1.4-0.01.3-1.31.3-0.6-1.2
Reaction time num false alarms AUC0.61.43.71.9-1.21.81.30.91.7-0.7-1.4-0.8-1.0-1.1-1.10.41.0-1.21.1-0.4-0.9
Reaction time trials correct on left0.41.33.2-1.10.5-1.4-0.8-0.8-1.50.51.01.01.21.01.4-1.1-1.11.8-0.61.01.6
Reaction time trials on left0.41.33.2-1.20.5-1.4-0.9-0.8-1.50.61.01.11.21.01.5-1.1-1.11.8-0.61.01.6
Reaction time mean0.10.21.20.00.40.1-0.10.30.3-0.3-0.40.20.0-0.50.01.10.0-0.4-0.3-0.60.2
Reaction time mean AUC0.10.21.30.10.40.2-0.10.20.3-0.1-0.50.30.1-0.50.11.1-0.0-0.3-0.4-0.50.4
Median of all reaction times0.10.21.90.00.50.1-0.20.20.3-0.1-0.40.40.2-0.50.21.4-0.1-0.4-0.5-0.40.4
Reaction time omissions0.10.10.4-0.70.3-0.5-0.5-0.1-0.50.40.20.10.30.70.30.1-0.00.2-0.10.40.2
Reaction time false alarm rate2.23.06.22.5-1.42.51.71.42.4-1.0-2.0-1.3-1.6-1.7-1.80.91.5-2.21.3-1.0-1.7
Reaction time premature initiation rate2.13.37.5-1.41.9-1.5-1.9-2.6-1.42.71.71.91.81.41.61.6-2.11.4-1.32.31.1
Reaction time premature initiations1.33.96.7-1.71.8-1.9-2.0-2.6-2.02.52.02.12.01.72.00.7-2.22.1-1.32.41.8
Std. dev. reaction times0.00.10.50.0-0.00.00.20.30.1-0.7-0.0-0.0-0.1-0.1-0.10.20.2-0.10.6-0.3-0.1
Reaction time trials completed0.41.33.2-1.20.5-1.4-0.9-0.8-1.50.61.01.11.21.01.5-1.1-1.11.8-0.61.01.6
Reaction time trials AUC0.31.12.7-1.00.5-1.3-0.8-0.7-1.40.50.81.01.10.81.4-1.1-1.01.6-0.70.81.5
Run reversals in cocaine runway, females0.20.22.4-0.30.4-0.1-0.5-0.2-0.10.30.50.30.30.40.21.5-0.1-0.10.40.70.0
Run reversals in cocaine runway, males0.00.00.20.10.40.10.1-0.1-0.00.2-0.0-0.1-0.1-0.1-0.2-0.1-0.1-0.20.10.1-0.5
Latency to leave start box in cocaine runway0.10.20.60.0-0.50.30.20.50.20.10.3-0.6-0.70.0-0.7-0.40.7-0.30.2-0.1-0.7
Latency to leave start box in cocaine runway, F0.50.61.61.2-1.01.11.00.71.0-0.3-0.2-0.8-0.9-0.6-0.9-0.50.7-0.60.9-0.0-0.7
Latency to leave start box in cocaine runway, M0.40.31.6-1.30.1-0.8-0.60.1-0.60.30.8-0.3-0.40.6-0.5-0.50.60.1-0.5-0.2-0.7
Std. dev. time between licks in bursts0.71.32.3-1.51.2-1.5-1.4-1.2-1.41.01.41.11.11.20.70.6-1.10.7-1.01.20.0
Total sessions with >9 infusions0.10.10.3-0.20.3-0.1-0.2-0.2-0.10.50.1-0.1-0.20.30.1-0.30.10.3-0.40.20.3
Short access day 1 total inactive lever presses1.12.14.71.3-2.01.31.71.81.1-1.7-1.2-1.5-1.6-0.8-1.4-2.21.6-0.41.1-1.1-1.1
Short access day 10 total inactive lever presses0.00.22.20.2-0.70.20.40.20.10.5-0.0-0.5-0.40.1-0.3-1.50.20.4-0.10.0-0.1
Short access day 1 total infusions0.10.10.50.3-0.10.30.00.30.30.4-0.5-0.1-0.1-0.40.20.10.20.1-0.4-0.00.7
Short access day 10 total infusions0.00.10.3-0.30.4-0.2-0.3-0.0-0.3-0.10.00.10.10.30.30.00.00.5-0.30.30.6
Short access total infusions0.10.20.40.3-0.30.40.30.70.3-0.5-0.7-0.5-0.5-0.4-0.0-0.40.60.0-0.2-0.40.5
Short access day 1 locomotion0.50.81.7-0.41.0-0.6-0.9-1.0-0.71.30.20.91.10.51.10.6-1.11.0-1.30.91.1
Short access day 10 total locomotion0.83.15.3-2.32.1-2.1-2.3-1.7-2.11.71.41.41.71.91.60.8-1.41.5-2.21.51.1
Short access total locomotion2.03.04.3-1.91.8-1.9-2.1-1.9-2.02.01.51.31.71.91.70.4-1.61.8-2.01.71.4
One hour access (0.3 mA shock)0.91.03.70.6-1.00.81.01.40.8-1.9-0.9-1.2-1.1-0.7-0.5-0.91.3-0.30.7-1.40.3
Compulsive drug intake1.62.34.9-1.62.1-1.4-2.0-1.7-1.12.11.21.61.51.01.12.2-1.20.5-1.90.90.5
One hour access (shock baseline)1.54.09.11.5-2.41.72.22.61.6-3.0-2.0-2.4-2.2-1.5-1.5-2.02.3-1.11.5-2.3-0.5
Social response proportion0.30.41.1-0.90.1-1.0-0.30.0-1.1-0.50.70.20.70.80.5-0.7-0.50.50.30.30.1
Social responses0.20.31.6-0.6-0.3-0.70.10.3-0.8-0.80.70.00.30.80.2-1.3-0.10.60.6-0.0-0.0
Social time0.60.92.2-1.21.1-1.3-1.1-0.7-1.20.31.01.11.50.81.00.8-1.00.5-0.60.80.4
Soleus weight0.82.37.12.7-2.02.11.81.41.8-1.0-2.4-0.7-0.7-2.3-0.6-1.30.2-0.80.1-1.30.1
Bone: stiffness0.10.10.40.2-0.30.20.1-0.20.20.50.40.1-0.20.1-0.3-0.20.2-0.20.60.5-0.5
Tibialis anterior weight1.45.08.12.6-2.82.42.72.52.2-2.3-2.2-2.2-2.4-1.9-2.3-2.11.9-1.71.8-2.0-1.9
Time to tail flick, vehicle, before self-admin0.20.20.80.9-0.60.70.40.20.5-0.8-0.40.00.3-0.30.20.5-0.10.10.70.20.3
Time to tail flick, vehicle, after self-admin0.10.21.0-0.70.1-0.4-0.5-0.0-0.30.10.3-0.2-0.11.00.00.40.40.30.00.3-0.1
Time to tail flick, test, before self-admin0.20.20.7-0.40.1-0.4-0.4-0.5-0.40.90.30.40.40.00.4-0.4-0.20.7-0.70.40.5
Time to tail flick, test, after self-admin1.11.23.91.2-1.61.01.31.20.8-1.0-1.0-0.9-1.0-0.9-1.0-2.00.8-0.40.4-0.9-0.8
Delta time to tail flick, vehicle, before/after SA0.40.52.2-1.50.7-1.0-0.8-0.3-0.90.70.9-0.1-0.11.20.0-0.00.30.3-0.40.3-0.2
Delta time to tail flick, test, before/after SA0.40.51.20.6-0.90.50.90.90.4-1.1-0.5-0.6-0.8-0.3-0.8-1.00.6-0.50.7-0.8-0.7
Tibia length0.30.72.31.30.21.00.0-0.21.00.9-1.40.70.6-1.10.21.5-0.9-0.5-0.80.10.3
Ambulatory time before self-admin0.00.10.5-0.30.6-0.1-0.4-0.0-0.1-0.10.2-0.1-0.1-0.20.10.40.3-0.2-0.7-0.30.3
Ambulatory time after self-admin0.10.21.0-0.40.6-0.0-0.50.00.00.2-0.1-0.1-0.1-0.1-0.01.00.3-0.4-0.9-0.40.1
Bone: tissue strength0.90.93.8-0.10.4-0.6-0.6-0.7-0.70.30.11.21.50.11.60.0-1.21.5-0.80.51.9
Total heroin consumption0.30.30.7-0.20.9-0.3-0.5-0.7-0.20.90.20.50.7-0.20.70.6-0.60.2-0.8-0.00.8
Bone: trabecular number0.30.52.70.00.80.1-0.5-0.20.30.9-0.70.30.6-0.70.41.4-0.4-0.4-1.6-0.30.5
Bone: trabecular spacing0.50.73.20.5-1.00.30.90.6-0.1-1.30.5-0.5-0.50.5-0.4-1.70.40.51.80.3-0.3
Bone: trabecular thickness1.21.76.6-0.41.8-0.4-1.3-1.00.01.7-0.61.21.5-0.81.12.6-1.2-0.2-2.5-0.11.2
Bone: trabecular tissue density0.10.20.4-0.60.5-0.6-0.4-0.4-0.5-0.20.50.40.20.60.20.40.10.30.20.00.1
Water consumed over 24 hours1.01.94.4-1.81.2-2.0-1.3-1.4-2.10.21.81.51.31.71.2-0.4-1.31.7-0.70.90.7
Number of responses in last shaping day0.10.20.9-0.3-0.1-0.1-0.0-0.1-0.10.10.9-0.1-0.40.7-0.4-0.10.50.10.70.4-0.6