Hub : Genes

Pdlim1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Pdlim1 0.3 0.17 1.3e-05 0.12 0.2 0.13 0.17 8.3e-04 1.3e-05 4.6e-04 7.4e-05
2 Liver mRNA stability Pdlim1 0.05 0.03 1.8e-05 0.01 0.03 0.02 0.02 1.5e-02 3.0e-04 3.3e-03 2.1e-03
3 IC gene expression Pdlim1 0.12 0.09 6.7e-04 0.05 0.04 0.06 0.08 2.7e-03 9.4e-03 2.3e-03 3.9e-04
4 Brain gene expression Pdlim1 0.11 0.07 1.4e-11 0.11 0.12 0.08 0.12 3.0e-10 2.9e-11 3.7e-08 8.1e-11
5 Eye gene expression Pdlim1 0.8 0.16 3.1e-06 0.26 0.24 0.19 0.23 8.1e-05 1.3e-04 8.4e-04 1.7e-04
6 Adipose mRNA stability Pdlim1 0.03 0.02 3.6e-03 0.01 0.01 0.01 0.01 4.0e-02 8.5e-03 3.7e-02 4.8e-02
7 pVTA gene expression Pdlim1 0.07 0.04 3.8e-06 0.06 0.08 0.07 0.07 1.0e-05 6.7e-07 3.7e-06 3.4e-06
8 PL gene expression Pdlim1 0.14 0.09 0.0e+00 0.15 0.17 0.18 0.18 2.2e-16 1.4e-18 1.6e-19 7.4e-19
9 Adipose gene expression Pdlim1 0.19 0.15 2.6e-06 0.01 0.03 0.06 0.04 1.4e-02 1.3e-04 4.5e-07 3.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.12.1-1.31.3-1.5-1.11.2-0.9-0.7-0.9-0.1
Area under the delay curve1.61.82.91.2-1.20.71.4-1.41.61.71.21.5
BMI with tail0.41.53.1-1.51.5-1.8-1.31.1-0.9-0.7-1.2-0.1
BMI without tail0.00.20.5-0.50.5-0.1-0.40.3-0.3-0.2-0.70.1
Body weight0.21.11.7-0.80.8-0.2-1.01.3-1.2-1.3-1.1-1.2
Weight adjusted by age0.20.30.7-0.70.8-0.9-0.50.4-0.3-0.1-0.30.6
Bone surface1.42.53.4-1.81.8-1.7-1.71.7-1.6-1.4-1.4-0.8
Bone volume1.62.93.7-1.91.9-1.6-1.91.9-1.7-1.6-1.6-1.0
Breakpoint value in progressive ratio session0.50.61.40.9-0.91.20.7-1.00.70.50.20.4
Number of licking bursts1.72.84.31.5-1.40.71.7-1.91.92.11.71.8
Context. condit. distance diff. score0.30.30.4-0.60.6-0.4-0.70.5-0.6-0.7-0.6-0.6
Locomotion velocity, session 15.15.57.32.3-2.21.62.5-2.62.62.72.12.3
Locomotion distance, session 11.82.32.71.6-1.61.31.6-1.61.61.61.41.3
Locomotion velocity, session 21.01.21.71.0-1.00.71.2-1.21.31.30.81.1
Locomotion distance, session 20.81.11.71.0-1.00.61.2-1.11.21.31.30.9
Locomotion velocity, session 30.10.20.60.3-0.40.80.1-0.1-0.0-0.20.2-0.6
Locomotion distance, session 30.70.73.20.1-0.21.1-0.30.5-0.7-1.0-0.3-1.8
Stereotopy head waving bouts, day 30.20.20.40.4-0.40.40.4-0.50.50.50.30.6
Stereotopy head waving duration, day 30.50.61.50.6-0.50.20.7-0.80.91.00.61.2
Locomotion velocity, session 70.60.71.1-0.80.7-0.4-0.90.9-0.9-1.0-0.6-1.0
Locomotion distance, session 70.91.11.5-1.11.0-0.8-1.11.2-1.2-1.2-0.6-1.2
Stereotopy head waving bouts, day 72.32.63.51.7-1.71.61.6-1.91.71.61.11.4
Stereotopy head waving duration, day 70.81.01.41.1-1.11.01.0-1.21.11.00.50.9
Locomotion velocity, session 80.00.10.20.2-0.20.40.2-0.30.20.10.20.1
Locomotion distance, session 80.10.10.20.1-0.1-0.00.2-0.40.40.40.30.4
Degree of sensitization distance0.40.41.6-0.20.2-0.90.3-0.30.50.70.31.3
Degree of sensitization stereotypy2.52.73.61.8-1.81.71.7-1.91.71.61.11.2
Conditioned locomotion1.72.02.5-1.51.5-1.6-1.61.4-1.4-1.4-1.4-0.4
Cocaine response after cond. corrected0.10.20.70.2-0.2-0.30.3-0.30.40.50.30.8
Cocaine response after cond. not corrected0.30.30.40.6-0.60.50.6-0.50.60.50.50.5
Cocaine response before conditioning1.21.44.11.4-1.42.01.2-1.00.80.61.0-0.3
Saline control response1.82.33.51.7-1.71.91.6-1.61.51.31.30.8
Bone: connectivity density1.93.05.9-2.12.1-2.4-1.81.7-1.5-1.2-1.4-0.5
Bone: cortical apparent density1.62.23.81.3-1.30.71.6-1.51.61.71.32.0
Bone: cortical area1.42.13.7-1.11.00.2-1.51.5-1.7-1.9-1.4-1.8
Bone: cortical porosity0.40.52.0-0.00.1-0.70.4-0.40.60.90.41.4
Bone: cortical porosity0.10.10.6-0.20.2-0.60.1-0.10.20.40.20.8
Bone: cortical thickness0.60.94.41.1-1.22.10.7-0.60.40.10.3-0.3
Bone: cortical thickness2.32.84.71.9-1.92.21.7-1.91.61.41.21.0
Bone: cortical tissue density1.72.34.31.3-1.30.61.6-1.51.71.81.32.1
Condit. Reinf. active minus inactive responses0.40.40.70.8-0.80.70.7-0.40.60.50.80.1
Condit. Reinf. active-inactive response ratio0.10.10.20.3-0.40.50.3-0.00.10.10.5-0.3
Condit. Reinf. active responses0.20.30.60.6-0.60.60.6-0.30.40.40.80.1
Condit. Reinf. inactive responses0.20.30.40.5-0.40.30.5-0.50.60.60.60.6
Incentive salience index mean0.40.51.40.9-0.91.20.7-0.50.50.30.7-0.3
Condit. Reinf. lever presses0.50.72.01.0-1.01.40.8-0.70.60.40.6-0.1
Condit. Reinf. active minus inactive responses2.22.83.3-1.81.8-1.7-1.71.7-1.7-1.6-1.5-1.5
Condit. Reinf. active-inactive response ratio1.11.32.0-1.31.4-1.4-1.21.1-1.1-0.9-1.0-0.6
Condit. Reinf. active responses1.62.24.1-1.31.3-0.7-1.51.4-1.6-1.8-1.4-2.0
Condit. Reinf. inactive responses0.50.62.60.3-0.31.3-0.30.1-0.5-0.9-0.4-1.6
Condit. Reinf. lever presses0.10.20.70.5-0.50.80.3-0.30.1-0.10.1-0.5
Condit. Reinf. lever reinforcers received0.81.12.6-0.80.8-0.3-1.11.0-1.2-1.3-1.0-1.6
Conditioned reinforcement - actives0.60.91.71.1-1.10.81.2-0.80.91.01.30.3
Conditioned reinforcement - inactives0.50.71.21.0-0.90.50.9-1.10.90.80.40.4
Conditioned locomotion0.40.60.80.9-0.90.80.9-0.60.70.70.8-0.1
Patch foraging indifference point 0 sec0.10.20.60.6-0.60.80.4-0.20.20.00.3-0.3
Patch foraging indifference point AUC3.85.57.42.7-2.62.42.5-2.72.42.22.20.8
Delay disc. indifference point, 0s delay0.50.61.9-0.91.0-1.4-0.60.5-0.3-0.1-0.80.6
Delay disc. indifference point, 16s delay1.11.21.51.1-1.00.81.1-1.21.21.20.91.1
Delay disc. indifference point, 2s delay0.30.31.30.00.0-0.40.4-0.40.60.90.41.2
Delay disc. indifference point, 24s delay4.14.65.22.3-2.31.92.3-2.22.32.22.31.5
Delay disc. indifference point, 4s delay0.90.91.60.9-0.80.51.0-1.01.21.30.81.0
Delay disc. indifference point, 8s delay3.64.25.62.0-2.01.52.2-2.22.32.41.91.8
Indifference point function ln k2.84.86.2-2.52.5-2.1-2.32.5-2.3-2.1-2.2-0.8
Indifference point function log k2.84.86.2-2.52.5-2.1-2.32.5-2.3-2.1-2.2-0.8
Patch foraging total patch changes 0 sec0.10.20.70.5-0.50.80.3-0.10.1-0.10.2-0.5
Patch foraging total patch changes 12 sec3.85.06.22.5-2.52.12.4-2.52.32.12.21.0
Patch foraging total patch changes 18 sec1.32.02.81.6-1.61.01.5-1.71.61.51.30.7
Patch foraging total patch changes 24 sec0.50.81.61.2-1.21.30.9-0.80.80.60.9-0.4
Patch foraging total patch changes 6 sec3.85.98.12.8-2.82.72.6-2.52.42.12.20.9
Patch foraging time to switch 0 sec0.51.11.80.9-0.90.31.0-1.11.21.30.81.4
Patch foraging water rate 0 sec0.71.52.6-1.21.2-0.7-1.41.1-1.3-1.3-1.6-0.8
Patch foraging water rate 12 sec0.30.61.6-0.50.5-0.1-0.70.7-0.8-0.9-0.8-1.3
Patch foraging water rate 18 sec0.30.51.0-0.60.6-0.2-0.70.6-0.8-0.8-0.6-1.0
Patch foraging water rate 24 sec0.30.40.8-0.70.7-0.4-0.70.6-0.7-0.7-0.9-0.2
Patch foraging water rate 6 sec0.10.10.5-0.30.3-0.0-0.30.2-0.3-0.3-0.7-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.80.1-0.10.1-0.20.2-0.3-0.5-0.1-0.9
Distance traveled before self-admin0.10.10.9-0.00.00.20.10.00.20.30.40.9
Distance traveled after self-admin0.30.40.7-0.80.8-0.5-0.50.7-0.5-0.30.20.8
Extensor digitorum longus weight0.10.60.9-0.80.8-1.0-0.80.9-0.8-0.7-0.4-0.4
Bone: elastic displacement0.50.62.6-0.70.7-1.6-0.40.3-0.10.2-0.41.0
Bone: elastic work0.40.51.5-0.80.8-1.2-0.60.4-0.3-0.2-0.60.6
Bone: endosteal estimation2.76.07.4-2.72.7-2.4-2.62.7-2.5-2.4-2.2-1.7
Bone: endosteal perimeter2.96.17.5-2.72.7-2.4-2.72.7-2.6-2.4-2.2-1.5
Epididymis fat weight1.65.46.9-2.62.6-2.2-2.52.4-2.4-2.2-2.6-1.0
Delta time in closed arm before/after self-admin0.10.10.20.1-0.10.5-0.10.1-0.2-0.3-0.4-0.4
Delta time in open arm before/after self-admin0.30.30.9-0.70.7-0.9-0.60.4-0.4-0.2-0.50.2
Diff in mean of infusions in LGA sessions0.60.81.5-0.90.9-1.1-1.00.7-0.8-0.8-1.20.1
Delay discount exponential model param1.82.03.0-1.31.3-0.9-1.51.5-1.7-1.7-1.3-1.4
Extinction: sum of active levers before priming0.20.20.5-0.10.10.2-0.40.1-0.4-0.6-0.7-0.6
Active lever presses in extinction session 60.60.61.5-0.80.9-1.1-0.60.1-0.10.1-1.11.2
Bone: final force0.10.20.4-0.20.10.5-0.30.5-0.5-0.6-0.4-0.4
Bone: final moment0.20.30.7-0.40.40.3-0.60.7-0.7-0.8-0.6-0.5
Food consumed during 24 hour testing period0.71.02.21.2-1.21.51.0-0.90.80.60.90.3
Glucose0.30.41.3-0.30.30.2-0.60.5-0.7-0.9-0.4-1.1
Heart weight1.32.04.7-0.90.90.0-1.41.2-1.5-1.8-1.6-2.2
Delay discount hyperbolic model param1.21.42.3-1.01.0-0.6-1.21.2-1.4-1.5-1.1-1.3
Intermittent access intake day 1-15 change0.71.52.3-1.31.3-1.5-1.21.3-1.2-1.1-0.8-1.1
Intermittent access intake escalation1.02.13.4-1.61.5-1.8-1.51.6-1.5-1.3-1.0-1.2
Intermittent access intake escalation 21.31.53.3-1.31.3-1.8-1.11.3-1.1-0.9-0.7-1.3
Intermitt. access day 1 inactive lever presses0.00.20.6-0.40.4-0.5-0.20.3-0.10.1-0.00.8
Intermitt. access day 15 inactive lever presses0.20.50.7-0.70.6-0.8-0.70.8-0.7-0.7-0.4-0.9
Intermitt. access escalation Index0.60.91.0-0.90.9-1.0-1.00.9-1.0-1.0-0.7-1.0
Intermittent access day 1 total infusions0.10.20.60.3-0.30.40.4-0.50.40.40.10.8
Intermittent access day 15 total infusions1.11.62.1-1.21.2-1.0-1.31.3-1.4-1.4-1.1-1.4
Intermittent access terminal intake (last 3 days)0.30.30.8-0.50.5-0.4-0.50.6-0.6-0.6-0.5-0.9
Intermittent access total infusions0.10.10.1-0.30.3-0.1-0.20.3-0.3-0.3-0.2-0.3
Intermittent access day 1 locomotion0.30.40.6-0.60.6-0.6-0.70.8-0.6-0.6-0.5-0.2
Intermittent access day 15 total locomotion0.40.70.90.9-0.80.90.9-0.90.90.90.60.7
Intermittent access total locomotion0.20.31.30.3-0.30.20.4-0.40.50.70.21.1
Intermittent access standard deviation0.20.40.7-0.60.5-0.7-0.60.7-0.7-0.7-0.4-0.8
Left kidney weight0.10.73.60.9-0.91.90.6-0.30.2-0.10.0-0.6
Right kidney weight0.31.36.21.4-1.42.50.9-0.70.60.20.40.0
Cocaine induced anxiety1.01.42.0-1.41.4-1.0-1.31.2-1.2-1.0-1.40.2
Post-drug Anxiety2.12.33.5-1.71.7-1.2-1.61.4-1.6-1.5-1.9-0.4
Baseline Anxiety0.30.30.9-0.40.3-0.4-0.50.3-0.7-0.8-0.5-0.9
Tail length0.10.31.10.1-0.11.1-0.20.4-0.5-0.7-0.4-0.8
Length with tail0.20.73.20.9-0.91.80.40.1-0.1-0.40.3-1.1
Length without tail0.10.20.80.5-0.50.70.30.1-0.1-0.20.2-0.9
Times rat made contact with spout0.30.30.50.5-0.50.50.6-0.50.60.60.70.4
Lifetime Intake0.10.10.1-0.30.3-0.1-0.30.2-0.3-0.2-0.30.1
Liver weight, left0.00.10.2-0.0-0.00.5-0.10.4-0.2-0.2-0.20.0
Liver weight, right0.40.81.1-0.80.8-0.2-1.01.0-1.0-1.0-1.0-0.4
Locomotor activity0.00.10.40.2-0.20.70.0-0.20.0-0.1-0.1-0.2
Locomotor testing distance0.10.21.00.4-0.41.00.1-0.30.20.0-0.20.0
Locomotor testing rearing0.10.20.4-0.60.6-0.2-0.60.5-0.5-0.4-0.60.1
Locomotion in novel chamber2.53.24.7-2.12.2-2.0-2.01.7-1.7-1.5-1.7-0.2
Locomotion in novel chamber post-restriction0.10.21.00.5-0.51.00.3-0.30.20.00.3-0.4
Fecal boli incidents, locomotor time 10.00.00.10.0-0.0-0.30.0-0.20.30.20.00.2
Change in fecal boli incidents, locomotor task0.10.10.30.1-0.10.30.00.1-0.2-0.20.3-0.5
Time >=10cm from walls, locomotor time 10.91.03.31.0-1.11.80.7-0.40.1-0.20.5-1.5
Bouts of movement, locomotor time 11.82.02.51.3-1.31.11.5-1.41.51.61.51.4
Total resting periods, locomotor time 13.03.34.01.8-1.81.62.0-1.91.91.91.81.5
Rest time, locomotor task time 11.21.52.61.0-0.90.61.2-1.31.41.51.11.6
Distance moved, locomotor task time 10.91.34.0-0.60.50.1-1.01.1-1.3-1.6-0.6-2.0
Vertical activity count, locomotor time 10.30.84.0-0.30.20.1-0.60.7-0.9-1.1-0.3-2.0
Time >=10cm from walls, locomotor time 20.30.51.70.8-0.81.30.6-0.40.40.30.7-0.4
Bouts of movement, locomotor time 23.45.47.02.2-2.21.72.6-2.62.62.72.22.0
Total resting periods, locomotor time 23.56.27.92.4-2.41.92.8-2.82.82.82.42.1
Rest time, locomotor task time 22.32.93.61.7-1.71.31.7-1.91.91.91.61.6
Distance moved, locomotor task time 21.41.72.8-1.11.1-0.3-1.31.6-1.6-1.7-1.1-1.5
Vertical activity count, locomotor time 20.20.30.7-0.30.30.0-0.50.6-0.6-0.7-0.3-0.8
Light reinforcement 10.20.40.60.5-0.50.40.7-0.50.70.70.80.6
Light reinforcement 22.23.34.61.6-1.61.21.9-1.72.02.11.92.1
Bone: marrow area2.86.07.5-2.72.7-2.4-2.62.6-2.5-2.3-2.2-1.6
Bone: maximum diameter3.87.18.6-2.82.8-2.0-2.92.9-2.9-2.8-2.5-2.0
Bone: maximum force0.20.30.5-0.60.6-0.2-0.60.7-0.7-0.7-0.6-0.4
Bone: maximum moment0.30.60.8-0.80.8-0.4-0.80.9-0.9-0.9-0.7-0.5
Mean time between licks in bursts0.10.30.5-0.50.5-0.3-0.60.7-0.7-0.7-0.5-0.7
Mean num. licks in bursts1.62.43.5-1.51.4-0.7-1.61.8-1.8-1.9-1.4-1.6
Cd content in liver1.21.41.71.2-1.21.21.3-1.21.21.11.20.7
Co content in liver0.60.72.4-0.10.11.0-0.50.8-0.9-1.1-0.5-1.6
Cu content in liver5.86.98.02.7-2.72.12.8-2.82.82.82.32.5
Fe content in liver2.12.53.11.7-1.61.21.8-1.71.71.71.31.4
K content in liver1.41.41.81.1-1.10.71.3-1.31.31.31.11.2
Mg content in liver1.21.21.71.0-1.00.61.2-1.21.31.31.01.2
Mn content in liver6.16.810.32.3-2.20.92.8-2.83.03.22.43.0
Na content in liver1.81.92.71.4-1.31.11.4-1.61.51.50.91.6
Rb content in liver0.10.10.20.3-0.30.40.2-0.20.20.10.30.0
Se content in liver19.823.427.55.1-5.04.05.2-5.15.25.14.64.0
Sr content in liver0.60.50.60.7-0.70.70.7-0.80.70.70.60.8
Zn content in liver2.42.73.21.7-1.71.31.7-1.81.81.81.51.4
Bone: minimum diameter7.313.316.0-3.73.7-2.6-4.03.9-4.0-4.0-3.5-3.2
Time in familiar zone, hab. session 10.20.20.8-0.60.6-0.9-0.50.4-0.3-0.2-0.30.1
Time in novel zone, hab. session 10.50.50.80.8-0.80.70.8-0.70.70.70.90.6
Total zone transitions, hab. session 10.30.40.70.5-0.50.20.6-0.60.70.70.60.8
Total locomotion distance, hab. session 12.23.13.51.9-1.91.61.9-1.91.91.81.71.4
Locomotion velocity, hab. session 13.44.85.82.4-2.42.32.3-2.32.22.12.01.4
Time in familiar zone, hab. session 20.30.40.7-0.60.6-0.6-0.60.4-0.5-0.5-0.8-0.6
Time in novel zone, hab. session 20.60.61.00.8-0.80.70.8-0.60.70.71.00.6
Total zone transitions, hab. session 20.10.20.20.4-0.40.40.5-0.40.40.40.50.1
Total locomotion distance, hab. session 20.50.70.90.9-0.91.00.9-0.90.80.80.70.3
Locomotion velocity, hab. session 20.71.01.21.1-1.11.01.1-1.11.01.00.90.5
Novel to familiar place preference ratio0.40.41.5-0.10.1-1.00.3-0.30.60.90.31.2
Novelty place preference0.40.51.5-0.20.2-1.10.3-0.30.50.80.31.2
Time in novel zone, NPP test0.40.51.5-0.20.2-1.20.3-0.20.50.90.41.2
Total zone transitions, NPP test0.40.51.40.9-0.91.20.7-0.60.50.40.8-0.2
Total locomotion distance, NPP test2.83.85.72.2-2.22.42.1-2.01.91.71.80.8
Locomotion velocity, NPP test2.23.15.72.1-2.12.41.9-1.81.61.41.50.5
Intraocular pressure0.10.21.1-0.10.2-0.4-0.0-0.20.20.3-0.51.1
Delta distance traveled before/after self-admin1.71.92.7-1.61.6-1.6-1.41.4-1.4-1.3-1.2-0.4
Delta ambulatory time before/after self-admin2.32.84.1-1.91.9-2.0-1.81.8-1.7-1.6-1.5-0.6
Parametrial fat weight0.20.41.60.6-0.61.20.1-0.3-0.1-0.5-0.3-1.2
Pavlov. Cond. lever latency0.30.41.6-0.70.8-1.3-0.50.4-0.3-0.2-0.30.2
Pavlov. Cond. magazine entry latency0.91.14.11.3-1.32.00.9-0.80.50.20.6-0.6
Pavlov. Cond. change in total contacts0.30.31.40.6-0.61.20.3-0.20.0-0.20.1-0.8
Pavlov. Cond. index score1.01.33.81.4-1.41.91.1-1.00.80.60.8-0.2
Pavlov. Cond. latency score0.70.93.21.2-1.21.80.8-0.80.60.30.5-0.4
Pavlov. Cond. lever contacts0.60.72.61.0-1.11.60.8-0.70.60.40.5-0.2
Pavlov. Cond. magazine entry number0.30.31.4-0.60.7-1.2-0.40.2-0.10.1-0.30.7
Pavlov. Cond. intertrial magazine entries0.20.30.40.5-0.50.20.5-0.40.50.60.60.5
Pavlov. Cond. lever-magazine prob. diff.1.01.23.31.3-1.41.81.1-0.90.80.60.8-0.2
Pavlov. Cond. response bias0.50.62.50.9-1.01.60.7-0.40.30.10.6-0.5
Pavlov. Cond. lever latency0.70.93.0-1.21.2-1.7-0.90.9-0.6-0.4-0.60.3
Pavlov. Cond. magazine entry latency0.50.61.61.0-1.01.20.8-0.70.60.40.7-0.1
Pavlov. Cond. change in total contacts0.10.20.80.5-0.50.90.2-0.30.0-0.2-0.1-0.6
Pavlov. Cond. index score0.81.13.11.3-1.31.81.0-1.00.70.50.7-0.3
Pavlov. Cond. latency score0.91.13.11.3-1.31.81.0-1.00.80.50.8-0.2
Pavlov. Cond. lever contacts0.60.82.61.1-1.11.60.8-0.80.50.30.5-0.4
Pavlov. Cond. magazine entry number1.92.45.3-1.91.9-2.3-1.61.5-1.3-1.0-1.3-0.1
Pavlov. Cond. intertrial magazine entries0.60.91.9-1.21.2-1.4-1.01.0-0.8-0.6-0.8-0.2
Pavlov. Cond. lever-magazine prob. diff.0.91.23.31.4-1.41.81.1-1.00.80.50.8-0.2
Pavlov. Cond. response bias0.81.03.21.2-1.31.80.9-0.90.70.40.6-0.4
Time in closed arm before self-admin0.10.21.10.0-0.10.20.2-0.20.30.50.41.0
Time in closed arm after self-admin0.30.31.50.2-0.30.40.40.00.30.60.71.2
Time in open arm before self-admin0.20.20.8-0.40.5-0.9-0.30.3-0.2-0.1-0.50.0
Time in open arm after self-admin0.20.20.8-0.40.4-0.6-0.4-0.1-0.2-0.2-0.9-0.1
Bone: periosteal estimation2.24.65.5-2.22.2-1.4-2.32.4-2.3-2.3-2.1-1.8
Bone: periosteal perimeter2.74.75.7-2.32.3-1.7-2.42.4-2.4-2.3-2.0-1.5
Bone: post-yield work0.30.40.6-0.70.7-0.4-0.70.8-0.7-0.7-0.5-0.6
Progressive ratio test 1 active lever presses0.30.41.00.5-0.50.20.6-0.50.70.80.71.0
Progressive ratio test 1 breakpoint0.40.51.00.6-0.60.40.7-0.60.70.80.71.0
Progressive ratio test 1 inactive lever presses0.20.20.7-0.40.4-0.6-0.40.2-0.2-0.2-0.60.8
Progressive ratio test 2 active lever presses0.20.30.50.4-0.40.20.6-0.50.60.70.60.5
Progressive ratio test 2 breakpoint0.20.30.50.4-0.40.20.6-0.50.60.70.60.5
Progressive ratio test 2 inactive lever presses0.10.20.50.1-0.1-0.00.4-0.40.50.70.40.7
Incentive Sensitization - Responses0.10.10.30.2-0.20.30.3-0.30.30.40.5-0.1
Incentive Sensitization - Breakpoint0.10.10.30.3-0.30.40.4-0.40.40.40.5-0.2
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.1-0.10.1-0.20.20.1-0.30.2
Progressive ratio0.40.71.8-0.60.6-0.8-0.70.7-0.7-0.8-0.8-1.4
Food seeking constrained by brief footshock0.40.51.00.9-0.91.00.7-0.70.50.40.5-0.2
Seeking ratio, punishment vs. effort1.11.62.31.3-1.31.51.2-1.31.11.11.31.1
Retroperitoneal fat weight0.20.71.2-0.70.7-0.4-0.80.6-0.9-1.0-1.1-1.1
Reaction time number correct0.81.53.1-1.61.6-1.8-1.21.3-1.1-0.7-0.8-0.2
Reaction time mean minus median0.30.61.8-0.40.4-0.0-0.70.8-0.9-1.1-0.7-1.3
Reaction time mean minus median AUC0.30.71.2-0.60.6-0.4-0.80.8-1.0-1.1-0.9-0.9
Reaction time num false alarms0.10.20.9-0.00.00.4-0.10.4-0.4-0.40.2-1.0
Reaction time num false alarms AUC0.20.31.7-0.10.00.6-0.20.5-0.5-0.60.2-1.3
Reaction time trials correct on left0.81.53.1-1.61.6-1.8-1.21.3-1.1-0.7-0.8-0.2
Reaction time trials on left0.81.53.1-1.61.6-1.8-1.21.3-1.1-0.8-0.8-0.2
Reaction time mean0.20.20.70.6-0.70.80.4-0.30.2-0.00.4-0.5
Reaction time mean AUC0.20.40.90.8-0.80.90.6-0.40.30.10.6-0.3
Median of all reaction times0.30.40.60.8-0.80.80.6-0.60.50.30.7-0.0
Reaction time omissions0.40.61.3-0.60.6-0.6-0.70.8-0.9-1.0-0.6-1.1
Reaction time false alarm rate0.30.51.70.6-0.71.30.3-0.20.0-0.20.5-1.1
Reaction time premature initiation rate0.40.52.10.7-0.71.10.3-0.1-0.1-0.40.0-1.4
Reaction time premature initiations0.30.52.4-0.10.10.2-0.30.5-0.7-0.8-0.4-1.6
Std. dev. reaction times0.40.72.8-0.20.10.3-0.50.8-0.9-1.2-0.4-1.7
Reaction time trials completed0.81.53.1-1.61.6-1.8-1.21.3-1.1-0.8-0.8-0.2
Reaction time trials AUC0.71.43.0-1.51.5-1.7-1.11.2-1.0-0.6-0.8-0.1
Run reversals in cocaine runway, females1.31.32.30.8-0.80.21.2-1.01.31.51.41.4
Run reversals in cocaine runway, males2.12.13.91.8-1.82.01.5-1.31.31.01.20.3
Latency to leave start box in cocaine runway3.94.45.5-2.32.3-2.3-2.32.2-2.1-1.9-2.0-1.1
Latency to leave start box in cocaine runway, F5.25.97.3-2.72.7-2.7-2.62.6-2.4-2.2-2.5-1.2
Latency to leave start box in cocaine runway, M0.30.30.6-0.70.7-0.8-0.60.6-0.6-0.4-0.3-0.1
Std. dev. time between licks in bursts0.30.40.80.6-0.60.30.6-0.70.70.80.50.9
Total sessions with >9 infusions0.20.31.50.2-0.20.10.3-0.20.40.50.51.2
Short access day 1 total inactive lever presses1.11.53.1-1.51.5-1.8-1.20.7-0.7-0.4-1.31.2
Short access day 10 total inactive lever presses0.00.00.20.1-0.1-0.0-0.1-0.1-0.1-0.2-0.40.5
Short access day 1 total infusions0.91.23.60.8-0.80.90.9-1.21.11.20.61.9
Short access day 10 total infusions0.91.11.41.1-1.11.21.1-0.91.01.01.11.0
Short access total infusions0.30.41.80.3-0.30.60.4-0.50.50.50.31.3
Short access day 1 locomotion0.30.31.8-0.60.6-0.5-0.20.20.10.40.21.3
Short access day 10 total locomotion0.40.82.00.7-0.70.60.8-0.70.91.00.81.4
Short access total locomotion0.30.41.80.2-0.2-0.00.4-0.30.60.80.81.3
One hour access (0.3 mA shock)0.10.20.3-0.50.5-0.4-0.30.6-0.3-0.2-0.2-0.4
Compulsive drug intake2.42.83.5-1.71.7-1.6-1.81.6-1.7-1.8-1.9-1.2
One hour access (shock baseline)0.10.20.40.3-0.30.60.4-0.10.20.30.6-0.4
Social response proportion1.31.54.8-1.51.5-2.2-1.11.1-0.9-0.6-0.9-0.3
Social responses1.21.61.8-1.31.3-1.3-1.31.2-1.2-1.2-1.2-1.3
Social time0.00.10.30.2-0.20.60.00.2-0.1-0.2-0.10.1
Soleus weight0.92.63.3-1.81.8-1.7-1.61.8-1.6-1.5-1.4-1.3
Bone: stiffness0.30.40.8-0.50.50.1-0.60.8-0.8-0.9-0.5-0.9
Tibialis anterior weight0.31.01.5-1.11.1-1.2-1.01.1-1.0-0.9-0.6-0.5
Time to tail flick, vehicle, before self-admin0.80.82.20.5-0.50.40.8-0.91.01.10.71.5
Time to tail flick, vehicle, after self-admin0.10.20.3-0.50.5-0.6-0.30.5-0.3-0.2-0.50.1
Time to tail flick, test, before self-admin0.10.10.2-0.40.4-0.2-0.40.3-0.3-0.4-0.40.2
Time to tail flick, test, after self-admin0.40.42.20.0-0.0-0.50.3-0.20.50.70.51.5
Delta time to tail flick, vehicle, before/after SA0.20.20.3-0.30.3-0.3-0.30.5-0.4-0.4-0.4-0.6
Delta time to tail flick, test, before/after SA0.60.61.40.5-0.50.10.7-0.60.81.00.81.2
Tibia length0.10.10.50.0-0.10.7-0.20.3-0.3-0.5-0.2-0.6
Ambulatory time before self-admin0.20.21.20.0-0.00.30.2-0.00.30.50.71.1
Ambulatory time after self-admin0.60.71.5-1.11.1-1.2-0.80.9-0.6-0.30.00.9
Bone: tissue strength0.40.40.6-0.50.5-0.4-0.60.7-0.7-0.7-0.5-0.8
Total heroin consumption0.10.20.80.2-0.10.6-0.1-0.50.0-0.3-0.90.0
Bone: trabecular number0.40.71.4-1.01.0-1.2-0.90.9-0.7-0.6-0.8-0.1
Bone: trabecular spacing0.20.20.90.5-0.60.90.3-0.20.1-0.10.2-0.6
Bone: trabecular thickness1.11.41.7-1.21.2-0.9-1.31.3-1.3-1.3-1.2-0.7
Bone: trabecular tissue density0.71.11.5-1.21.2-1.1-1.21.1-1.0-0.9-1.00.1
Water consumed over 24 hours0.50.60.90.7-0.70.50.9-0.80.90.91.00.8
Number of responses in last shaping day0.10.10.3-0.20.1-0.6-0.00.20.00.10.60.2