Hub : Genes

Pdgfb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Pdgfb 0.04 0.03 9.7e-04 0.04 0.03 0.04 0.03 3.7e-04 9.9e-04 7.7e-04 3.5e-03
2 RMTg gene expression Pdgfb 0.23 0.11 8.1e-04 0.04 0.12 0.12 0.1 4.3e-02 4.6e-04 3.8e-04 1.4e-03
3 Brain gene expression Pdgfb 0.08 0.04 3.1e-06 0.06 0.05 0.05 0.05 3.9e-06 1.4e-05 1.8e-05 3.9e-05
4 BLA gene expression Pdgfb 0.11 0.08 4.1e-03 0.02 0.02 0.03 0.02 1.9e-02 2.5e-02 6.9e-03 3.3e-02
5 NAcc gene expression Pdgfb 0.04 0.03 1.6e-04 0.01 0.02 0.02 0.01 2.3e-03 5.3e-04 3.4e-04 2.7e-03
6 PL isoform ratio NM_031524.1 0.03 0.02 1.0e-03 0.03 0.03 0.02 0.03 4.2e-04 2.2e-04 5.6e-03 4.7e-04
7 PL alternative TSS NM_031524.1 0.03 0.02 4.6e-03 0.02 0.03 0.02 0.02 5.1e-03 5.4e-04 5.5e-03 3.7e-03
8 PL alternative TSS XM_039078420.2 0.03 0.02 3.1e-03 0.02 0.02 0.02 0.02 1.1e-03 2.2e-03 3.1e-03 1.8e-03
9 Brain mRNA stability Pdgfb 0.04 0.03 6.4e-03 0.01 0.03 0.01 0.01 3.0e-02 2.1e-03 3.7e-02 1.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.20.30.50.40.30.50.6-0.1-0.2-0.4-0.2
Area under the delay curve2.02.34.91.82.22.11.81.5-0.8-1.20.8-0.2
BMI with tail0.41.43.4-1.3-1.5-1.8-1.3-0.80.41.0-1.20.2
BMI without tail0.20.62.0-0.1-1.4-0.7-0.6-0.30.60.7-1.30.1
Body weight1.04.29.5-2.6-2.6-2.4-2.9-3.1-0.10.6-0.2-0.7
Weight adjusted by age0.40.61.5-0.1-1.1-0.2-1.0-1.20.90.6-0.60.7
Bone surface0.10.20.40.10.50.70.2-0.0-0.4-0.60.5-0.4
Bone volume0.00.00.10.20.20.10.00.2-0.1-0.1-0.1-0.1
Breakpoint value in progressive ratio session0.20.20.4-0.40.4-0.30.60.5-0.6-0.40.3-0.6
Number of licking bursts0.30.52.11.10.51.40.90.50.3-0.30.00.4
Context. condit. distance diff. score5.36.412.5-2.7-3.3-3.2-3.5-3.01.32.1-1.11.0
Locomotion velocity, session 11.31.44.1-0.70.81.3-0.2-0.9-1.2-1.52.0-1.2
Locomotion distance, session 12.22.88.31.82.02.91.61.4-0.5-1.31.70.1
Locomotion velocity, session 20.20.20.4-0.60.4-0.3-0.1-0.1-0.6-0.40.4-0.5
Locomotion distance, session 24.25.810.42.33.23.22.72.4-1.7-2.41.8-1.1
Locomotion velocity, session 32.63.05.8-0.9-2.2-1.4-2.4-2.01.71.8-0.91.6
Locomotion distance, session 31.61.85.31.0-1.20.3-0.7-0.42.11.5-0.92.3
Stereotopy head waving bouts, day 31.01.12.5-1.50.50.0-0.3-0.7-1.4-1.21.1-1.6
Stereotopy head waving duration, day 31.92.26.9-2.6-0.2-1.1-1.2-1.6-1.6-0.91.0-1.9
Locomotion velocity, session 71.01.13.8-2.0-1.0-1.3-1.0-1.20.40.60.30.3
Locomotion distance, session 70.40.51.7-0.80.20.1-0.2-0.8-0.7-0.81.3-0.6
Stereotopy head waving bouts, day 73.13.55.7-2.1-2.4-2.4-2.4-2.01.11.7-1.10.7
Stereotopy head waving duration, day 72.83.47.1-1.8-2.2-2.7-1.9-1.31.32.0-1.80.9
Locomotion velocity, session 81.41.74.1-2.0-0.9-0.9-1.5-2.0-0.8-0.51.1-1.0
Locomotion distance, session 80.50.71.7-0.2-1.0-0.9-1.3-0.70.71.0-0.60.7
Degree of sensitization distance2.32.36.2-2.00.6-1.0-0.1-0.6-2.2-1.51.3-2.5
Degree of sensitization stereotypy2.72.95.3-1.5-2.2-2.3-2.0-1.61.31.8-1.21.0
Conditioned locomotion0.30.41.2-0.6-0.7-0.7-1.1-1.0-0.00.20.1-0.1
Cocaine response after cond. corrected0.30.41.0-0.40.60.1-0.1-0.1-1.0-0.90.8-0.9
Cocaine response after cond. not corrected0.10.20.4-0.10.5-0.1-0.00.2-0.6-0.50.3-0.6
Cocaine response before conditioning0.50.61.70.4-0.3-0.30.10.61.11.1-1.31.0
Saline control response0.71.01.5-0.4-1.2-0.8-1.1-0.71.21.2-1.10.8
Bone: connectivity density0.10.10.3-0.3-0.00.2-0.2-0.4-0.3-0.40.3-0.5
Bone: cortical apparent density1.31.73.90.9-1.3-0.2-1.0-0.72.01.6-1.51.8
Bone: cortical area0.60.92.2-1.00.8-0.5-0.1-0.1-1.5-1.01.0-1.3
Bone: cortical porosity0.50.52.0-1.20.1-1.40.20.3-0.8-0.2-0.0-0.9
Bone: cortical porosity1.31.43.9-2.00.2-1.7-0.2-0.3-1.4-0.70.8-1.6
Bone: cortical thickness0.30.51.60.21.30.20.80.7-0.8-0.70.5-0.4
Bone: cortical thickness1.31.53.50.71.91.20.80.8-1.4-1.51.5-0.8
Bone: cortical tissue density1.21.63.60.8-1.3-0.2-1.0-0.81.91.5-1.31.7
Condit. Reinf. active minus inactive responses0.10.10.40.20.30.60.1-0.0-0.0-0.30.1-0.1
Condit. Reinf. active-inactive response ratio0.40.40.7-0.5-0.6-0.6-0.8-0.70.60.6-0.40.6
Condit. Reinf. active responses0.40.51.91.40.30.80.60.80.60.2-0.90.3
Condit. Reinf. inactive responses0.91.13.51.90.10.81.01.20.90.4-1.40.5
Incentive salience index mean0.10.20.60.60.40.80.40.40.1-0.2-0.10.0
Condit. Reinf. lever presses0.20.20.50.70.30.50.60.70.2-0.0-0.50.1
Condit. Reinf. active minus inactive responses1.41.85.0-0.01.31.40.6-0.1-1.6-1.82.2-1.3
Condit. Reinf. active-inactive response ratio1.31.53.5-0.41.00.90.1-0.3-1.6-1.71.9-1.6
Condit. Reinf. active responses1.11.55.1-0.81.00.70.2-0.5-1.5-1.52.3-1.2
Condit. Reinf. inactive responses0.30.31.4-0.90.40.00.1-0.4-0.5-0.41.2-0.1
Condit. Reinf. lever presses0.40.51.30.90.71.01.20.8-0.4-0.60.1-0.3
Condit. Reinf. lever reinforcers received1.01.44.2-0.61.00.70.4-0.3-1.5-1.52.0-1.3
Conditioned reinforcement - actives0.91.54.10.01.61.40.70.7-1.2-1.42.0-0.4
Conditioned reinforcement - inactives2.94.36.70.92.42.62.21.8-2.0-2.42.2-1.5
Conditioned locomotion2.12.75.0-0.52.11.01.00.9-2.2-2.12.1-1.8
Patch foraging indifference point 0 sec0.20.30.90.50.50.50.60.3-0.5-0.7-0.4-1.0
Patch foraging indifference point AUC1.21.76.60.81.52.61.00.3-0.7-1.41.5-0.2
Delay disc. indifference point, 0s delay0.30.40.9-0.40.7-0.30.40.6-0.9-0.5-0.1-0.9
Delay disc. indifference point, 16s delay2.42.65.51.92.22.32.01.8-0.6-1.20.7-0.0
Delay disc. indifference point, 2s delay1.92.16.91.02.61.01.82.0-0.9-0.90.70.0
Delay disc. indifference point, 24s delay1.11.24.10.90.72.00.3-0.7-0.7-1.31.6-0.4
Delay disc. indifference point, 4s delay1.41.53.11.51.81.41.31.2-0.9-1.10.7-0.4
Delay disc. indifference point, 8s delay1.72.05.61.91.72.41.71.2-0.5-1.00.6-0.0
Indifference point function ln k1.52.66.8-1.1-2.0-2.6-1.8-1.31.01.7-1.30.6
Indifference point function log k1.52.66.8-1.1-2.0-2.6-1.8-1.31.01.7-1.30.6
Patch foraging total patch changes 0 sec0.30.50.91.00.80.80.90.8-0.4-0.6-0.6-0.7
Patch foraging total patch changes 12 sec0.50.71.3-0.21.20.70.40.2-1.1-1.10.7-1.0
Patch foraging total patch changes 18 sec1.92.95.1-0.01.91.91.70.8-2.0-2.31.5-2.0
Patch foraging total patch changes 24 sec0.30.51.60.21.01.30.90.5-0.4-0.80.5-0.4
Patch foraging total patch changes 6 sec1.72.65.10.72.02.21.50.9-1.5-2.11.1-1.6
Patch foraging time to switch 0 sec0.20.41.1-0.30.4-1.00.61.0-0.6-0.1-0.3-0.7
Patch foraging water rate 0 sec0.10.31.20.4-0.11.1-0.3-0.6-0.2-0.60.2-0.5
Patch foraging water rate 12 sec0.20.41.30.7-0.40.10.10.10.90.7-1.10.5
Patch foraging water rate 18 sec0.10.20.90.7-0.10.90.2-0.10.1-0.4-0.1-0.4
Patch foraging water rate 24 sec0.60.81.9-0.6-1.4-1.0-1.1-1.30.40.6-0.8-0.2
Patch foraging water rate 6 sec0.71.02.50.8-1.30.2-0.2-0.41.61.2-1.31.1
Seeking ratio, delayed vs. immediate footshock0.40.51.11.10.20.50.70.90.60.4-0.80.6
Distance traveled before self-admin1.11.53.51.01.90.91.61.9-1.0-0.90.2-0.5
Distance traveled after self-admin1.62.04.20.41.21.31.20.6-1.8-2.01.1-2.0
Extensor digitorum longus weight0.62.45.92.41.21.01.72.40.70.5-1.41.1
Bone: elastic displacement0.20.20.8-0.4-0.5-0.2-0.5-0.90.10.10.2-0.0
Bone: elastic work1.01.32.7-1.50.4-0.8-0.6-0.6-1.6-1.11.2-1.6
Bone: endosteal estimation0.71.53.4-1.60.2-0.7-0.7-0.9-1.6-1.21.2-1.8
Bone: endosteal perimeter0.71.55.2-2.3-0.4-1.5-1.1-1.0-1.1-0.40.8-1.2
Epididymis fat weight1.96.614.5-3.8-2.6-3.7-3.5-3.3-0.11.10.1-0.5
Delta time in closed arm before/after self-admin0.40.41.2-0.41.10.30.10.0-0.7-0.71.1-0.3
Delta time in open arm before/after self-admin0.10.10.40.60.00.40.50.40.0-0.2-0.0-0.1
Diff in mean of infusions in LGA sessions0.50.61.8-0.9-0.00.0-0.3-0.9-0.8-0.81.4-0.8
Delay discount exponential model param2.12.34.7-1.9-2.1-2.2-1.8-1.50.71.2-0.70.1
Extinction: sum of active levers before priming0.90.91.9-1.01.20.10.50.6-1.3-1.01.4-0.9
Active lever presses in extinction session 60.20.20.5-0.70.1-0.40.10.2-0.5-0.30.6-0.5
Bone: final force1.01.64.1-1.01.2-0.10.1-0.1-2.0-1.61.5-1.7
Bone: final moment1.21.94.7-1.11.20.0-0.0-0.2-2.2-1.71.6-1.9
Food consumed during 24 hour testing period0.81.12.4-1.60.6-0.20.0-0.3-1.5-1.11.2-1.4
Glucose0.10.20.7-0.4-0.2-0.50.40.4-0.5-0.2-0.1-0.8
Heart weight1.32.05.4-2.3-0.7-1.2-1.1-1.4-1.5-0.90.8-1.9
Delay discount hyperbolic model param2.02.34.9-1.9-2.2-2.0-1.8-1.60.71.1-0.6-0.0
Intermittent access intake day 1-15 change0.10.20.40.6-0.40.10.30.50.60.4-0.60.4
Intermittent access intake escalation0.20.40.70.9-0.50.30.20.50.80.6-0.80.7
Intermittent access intake escalation 20.20.20.40.5-0.40.20.30.50.60.4-0.70.4
Intermitt. access day 1 inactive lever presses0.31.12.9-0.10.60.40.70.4-1.6-1.31.0-1.7
Intermitt. access day 15 inactive lever presses0.61.22.00.60.91.41.11.0-1.1-1.41.1-1.1
Intermitt. access escalation Index0.40.51.80.5-0.20.10.40.40.90.7-1.40.8
Intermittent access day 1 total infusions2.03.35.9-0.22.41.41.51.2-2.3-2.22.3-1.6
Intermittent access day 15 total infusions1.01.52.71.01.61.61.31.5-0.9-1.11.1-0.3
Intermittent access terminal intake (last 3 days)1.11.52.80.61.71.41.31.4-1.0-1.21.3-0.4
Intermittent access total infusions3.64.27.70.12.81.91.91.7-2.4-2.42.6-1.5
Intermittent access day 1 locomotion2.32.94.70.32.21.51.81.8-1.9-1.91.6-1.5
Intermittent access day 15 total locomotion0.91.62.9-0.51.20.80.90.8-1.7-1.61.7-1.4
Intermittent access total locomotion2.22.65.0-0.91.41.11.00.5-2.2-2.22.1-2.0
Intermittent access standard deviation1.32.75.3-0.21.90.41.41.4-2.3-1.91.8-2.1
Left kidney weight3.817.848.2-6.9-2.6-5.1-5.3-5.5-2.3-0.42.7-2.6
Right kidney weight4.520.554.3-7.4-3.0-5.6-5.6-5.8-2.7-0.62.7-3.2
Cocaine induced anxiety0.71.03.6-1.9-0.7-1.0-1.2-1.2-0.5-0.10.8-0.5
Post-drug Anxiety1.01.12.4-1.0-1.5-0.8-1.6-1.50.70.7-0.20.4
Baseline Anxiety0.50.61.91.40.20.90.30.40.90.4-0.60.9
Tail length0.20.62.70.3-1.60.3-0.6-1.00.90.5-0.70.2
Length with tail0.83.310.0-1.8-2.5-1.6-2.7-3.20.30.60.2-0.4
Length without tail1.44.510.6-3.3-1.2-2.2-2.5-3.1-1.4-0.61.4-1.9
Times rat made contact with spout0.30.31.1-0.30.21.0-0.1-0.5-0.3-0.61.0-0.1
Lifetime Intake4.25.19.5-0.43.11.61.81.6-2.8-2.82.8-1.9
Liver weight, left1.42.44.3-1.4-1.8-1.7-2.1-1.91.21.5-0.51.3
Liver weight, right4.88.416.3-2.2-4.0-3.4-3.5-2.92.43.0-2.01.8
Locomotor activity0.81.33.7-1.9-1.1-1.1-1.6-1.6-0.30.10.2-0.6
Locomotor testing distance0.10.10.20.2-0.40.2-0.2-0.20.40.3-0.50.3
Locomotor testing rearing0.40.82.5-1.6-0.4-1.2-1.1-1.0-0.40.10.5-0.4
Locomotion in novel chamber2.12.75.61.8-1.00.30.30.92.31.8-2.42.2
Locomotion in novel chamber post-restriction0.50.81.80.90.50.20.91.30.90.7-1.01.2
Fecal boli incidents, locomotor time 11.52.24.2-0.11.61.81.20.4-1.8-2.11.5-1.7
Change in fecal boli incidents, locomotor task2.42.36.5-1.1-1.8-1.0-2.4-2.61.11.00.11.0
Time >=10cm from walls, locomotor time 10.70.72.0-0.60.1-0.2-0.4-0.7-1.2-1.01.0-1.4
Bouts of movement, locomotor time 10.70.82.4-1.6-0.8-0.9-1.1-1.3-0.10.10.8-0.0
Total resting periods, locomotor time 10.40.51.4-1.2-0.2-0.4-0.5-0.8-0.6-0.41.1-0.4
Rest time, locomotor task time 10.70.92.2-1.40.3-0.2-0.1-0.5-1.3-1.01.5-1.2
Distance moved, locomotor task time 10.71.01.70.3-1.0-1.0-1.1-0.51.21.3-1.31.0
Vertical activity count, locomotor time 10.20.41.3-0.1-1.1-0.3-0.7-0.80.50.3-0.8-0.1
Time >=10cm from walls, locomotor time 20.10.10.50.0-0.40.30.0-0.4-0.4-0.40.1-0.7
Bouts of movement, locomotor time 20.30.41.3-0.7-0.1-1.20.10.60.40.8-0.30.8
Total resting periods, locomotor time 20.20.30.7-0.60.4-0.80.50.8-0.00.30.20.4
Rest time, locomotor task time 20.40.51.70.10.80.70.40.0-0.8-0.91.3-0.5
Distance moved, locomotor task time 20.60.71.2-0.5-1.0-1.1-0.9-0.50.81.0-1.00.5
Vertical activity count, locomotor time 20.30.41.0-1.0-0.9-0.4-0.5-0.90.00.1-0.3-0.5
Light reinforcement 10.10.20.60.10.80.40.40.4-0.4-0.50.4-0.5
Light reinforcement 20.81.23.8-0.6-1.0-2.0-0.9-0.20.81.4-1.00.8
Bone: marrow area0.71.63.7-1.70.2-0.7-0.8-0.9-1.7-1.31.3-1.9
Bone: maximum diameter1.42.65.6-2.40.3-1.2-1.1-1.2-2.1-1.31.6-2.1
Bone: maximum force1.83.27.6-1.51.50.00.1-0.3-2.8-2.32.2-2.5
Bone: maximum moment2.03.58.2-1.71.50.0-0.0-0.5-2.9-2.42.3-2.6
Mean time between licks in bursts0.41.02.31.50.80.51.11.50.60.4-0.90.8
Mean num. licks in bursts0.60.92.2-1.5-0.8-1.0-1.4-1.3-0.20.20.7-0.2
Cd content in liver0.60.73.1-0.0-0.7-0.1-1.5-1.80.30.10.50.3
Co content in liver0.91.12.90.81.21.71.00.8-0.9-1.20.7-0.6
Cu content in liver3.54.112.13.51.52.42.52.90.5-0.2-1.10.7
Fe content in liver0.91.13.9-0.9-0.9-1.0-0.8-1.0-1.2-0.80.2-2.0
K content in liver0.20.20.50.7-0.10.40.50.50.40.2-0.30.4
Mg content in liver0.20.20.40.50.20.50.60.6-0.2-0.4-0.1-0.3
Mn content in liver0.30.41.0-0.2-0.4-0.5-0.2-0.30.90.9-0.51.0
Na content in liver0.40.41.71.3-0.00.70.60.80.1-0.2-0.6-0.2
Rb content in liver0.70.91.70.31.10.60.60.3-1.2-1.31.1-1.0
Se content in liver1.41.63.11.6-0.9-0.2-0.30.31.81.5-1.71.7
Sr content in liver2.82.46.92.60.51.31.31.81.40.9-1.51.7
Zn content in liver0.10.20.60.7-0.40.5-0.2-0.30.40.2-0.00.4
Bone: minimum diameter0.61.12.3-1.50.6-0.6-0.0-0.2-1.4-1.11.0-1.5
Time in familiar zone, hab. session 10.40.41.1-0.20.50.8-0.1-0.5-0.7-0.81.0-0.4
Time in novel zone, hab. session 10.50.51.6-0.5-0.9-1.3-0.5-0.20.30.6-0.8-0.2
Total zone transitions, hab. session 11.41.94.92.2-0.21.50.50.51.91.0-0.92.1
Total locomotion distance, hab. session 10.91.33.50.9-1.00.7-0.4-0.51.91.2-0.71.8
Locomotion velocity, hab. session 10.70.92.31.2-0.51.20.10.01.50.8-0.51.5
Time in familiar zone, hab. session 21.21.22.90.3-1.0-0.3-0.6-0.31.61.5-1.41.7
Time in novel zone, hab. session 21.11.22.7-0.40.90.30.50.3-1.5-1.51.3-1.6
Total zone transitions, hab. session 21.41.84.61.31.52.11.20.7-0.9-1.51.4-0.7
Total locomotion distance, hab. session 21.31.73.51.01.61.91.51.1-1.0-1.41.0-0.8
Locomotion velocity, hab. session 21.72.35.01.41.82.21.81.4-1.0-1.61.1-0.9
Novel to familiar place preference ratio1.41.53.8-1.0-1.8-1.4-2.0-1.80.50.7-0.20.1
Novelty place preference2.22.35.4-1.2-2.2-1.7-2.3-2.20.81.0-0.40.4
Time in novel zone, NPP test2.52.76.4-1.3-2.4-1.8-2.5-2.40.81.0-0.40.4
Total zone transitions, NPP test1.11.75.92.20.72.41.00.60.9-0.10.31.2
Total locomotion distance, NPP test0.60.83.51.20.91.90.80.30.0-0.60.70.2
Locomotion velocity, NPP test0.71.03.61.51.11.91.10.80.3-0.40.40.5
Intraocular pressure0.71.13.1-1.8-0.5-1.3-1.1-1.7-0.10.20.7-0.1
Delta distance traveled before/after self-admin1.31.34.1-1.2-1.1-0.2-1.1-2.0-0.7-0.81.0-1.3
Delta ambulatory time before/after self-admin1.11.43.5-1.1-0.70.1-1.0-1.9-1.0-1.21.4-1.5
Parametrial fat weight1.02.34.5-0.6-2.1-1.4-1.2-1.31.71.7-1.81.2
Pavlov. Cond. lever latency0.10.10.5-0.4-0.2-0.1-0.5-0.7-0.2-0.10.3-0.1
Pavlov. Cond. magazine entry latency0.70.91.90.51.31.01.31.4-0.5-0.70.6-0.0
Pavlov. Cond. change in total contacts1.81.94.10.82.01.41.91.7-1.0-1.30.7-0.7
Pavlov. Cond. index score0.40.51.10.11.00.71.00.9-0.6-0.70.6-0.4
Pavlov. Cond. latency score0.20.30.70.10.70.60.90.8-0.4-0.40.3-0.2
Pavlov. Cond. lever contacts0.40.51.60.60.80.61.21.3-0.0-0.2-0.30.0
Pavlov. Cond. magazine entry number0.70.91.8-0.5-1.4-1.1-1.3-1.20.40.7-0.8-0.1
Pavlov. Cond. intertrial magazine entries0.50.61.61.10.71.30.60.2-0.4-0.90.2-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.20.90.60.90.9-0.4-0.50.5-0.1
Pavlov. Cond. response bias0.60.81.80.41.30.81.31.3-0.5-0.60.5-0.1
Pavlov. Cond. lever latency0.40.51.5-0.8-0.5-0.5-1.2-1.00.40.50.40.8
Pavlov. Cond. magazine entry latency2.32.84.42.02.01.92.11.8-1.2-1.60.5-1.2
Pavlov. Cond. change in total contacts1.82.88.1-0.21.40.81.10.3-2.4-2.31.6-2.8
Pavlov. Cond. index score1.11.42.61.31.21.31.61.2-1.0-1.30.4-1.2
Pavlov. Cond. latency score1.31.73.11.41.41.61.81.3-1.0-1.40.5-1.2
Pavlov. Cond. lever contacts0.40.61.50.90.40.51.21.0-0.4-0.5-0.5-0.8
Pavlov. Cond. magazine entry number0.80.91.8-1.4-1.0-1.1-1.1-0.90.71.0-0.40.8
Pavlov. Cond. intertrial magazine entries0.50.73.1-1.80.1-0.3-0.5-0.7-0.9-0.61.1-0.6
Pavlov. Cond. lever-magazine prob. diff.1.01.32.51.31.21.31.61.3-0.9-1.10.2-1.1
Pavlov. Cond. response bias0.91.22.51.01.11.01.61.2-1.0-1.10.2-1.2
Time in closed arm before self-admin1.62.15.61.91.01.42.42.2-0.2-0.5-0.9-0.6
Time in closed arm after self-admin0.30.30.8-0.40.40.20.3-0.1-0.7-0.70.6-0.9
Time in open arm before self-admin0.60.61.3-0.1-0.7-0.2-1.0-0.91.00.9-0.41.2
Time in open arm after self-admin0.70.81.60.8-0.80.1-0.3-0.11.31.1-1.01.3
Bone: periosteal estimation0.81.83.9-1.70.6-0.9-0.6-0.7-1.9-1.41.3-2.0
Bone: periosteal perimeter1.42.47.9-2.8-0.3-1.6-1.4-1.5-1.5-0.71.2-1.6
Bone: post-yield work1.72.55.2-0.31.51.40.7-0.1-2.1-2.22.3-1.8
Progressive ratio test 1 active lever presses2.73.36.40.02.51.61.51.3-2.2-2.22.3-1.5
Progressive ratio test 1 breakpoint2.43.05.80.12.41.61.41.2-2.0-2.12.2-1.3
Progressive ratio test 1 inactive lever presses3.75.39.80.33.11.62.62.4-2.7-2.62.0-2.1
Progressive ratio test 2 active lever presses2.22.66.0-0.22.01.51.20.8-1.8-2.02.4-1.1
Progressive ratio test 2 breakpoint2.22.55.7-0.12.11.51.20.9-1.8-1.92.4-1.0
Progressive ratio test 2 inactive lever presses1.22.03.50.91.61.91.81.8-0.9-1.31.2-0.4
Incentive Sensitization - Responses0.10.10.40.10.30.50.40.2-0.0-0.30.70.2
Incentive Sensitization - Breakpoint0.10.10.7-0.10.30.40.30.1-0.2-0.30.80.1
Sum of active levers in priming session hrs 5-60.00.00.00.1-0.2-0.10.10.1-0.0-0.0-0.0-0.2
Progressive ratio0.20.40.80.20.60.50.60.4-0.8-0.80.3-0.9
Food seeking constrained by brief footshock0.30.41.2-0.70.70.1-0.3-0.2-0.8-0.61.1-0.5
Seeking ratio, punishment vs. effort0.10.10.5-0.60.3-0.3-0.2-0.2-0.3-0.10.7-0.1
Retroperitoneal fat weight2.39.823.4-4.8-2.9-4.5-4.2-4.1-0.11.3-0.2-0.6
Reaction time number correct0.91.74.70.2-1.3-0.4-0.3-0.02.01.8-1.22.2
Reaction time mean minus median0.00.00.10.3-0.1-0.10.10.4-0.1-0.0-0.2-0.1
Reaction time mean minus median AUC0.10.31.1-0.7-0.7-1.1-0.7-0.30.20.5-0.30.1
Reaction time num false alarms0.10.20.7-0.1-0.5-0.1-0.1-0.10.50.5-0.80.3
Reaction time num false alarms AUC0.20.30.60.0-0.6-0.1-0.2-0.30.70.6-0.80.5
Reaction time trials correct on left0.91.74.70.2-1.3-0.4-0.3-0.02.01.8-1.22.2
Reaction time trials on left0.91.74.90.3-1.2-0.3-0.30.02.11.8-1.22.2
Reaction time mean0.10.10.50.7-0.4-0.40.00.3-0.00.1-0.5-0.2
Reaction time mean AUC0.10.10.40.6-0.4-0.4-0.10.10.00.1-0.4-0.1
Median of all reaction times0.10.20.70.8-0.3-0.40.10.4-0.00.1-0.6-0.2
Reaction time omissions0.40.51.41.10.50.60.91.20.30.1-0.30.7
Reaction time false alarm rate0.00.00.20.1-0.1-0.1-0.1-0.1-0.1-0.0-0.5-0.4
Reaction time premature initiation rate1.31.84.6-0.21.20.90.80.5-1.9-1.81.3-2.2
Reaction time premature initiations0.20.41.0-0.30.40.60.40.3-0.9-0.80.8-1.0
Std. dev. reaction times0.10.20.6-0.0-0.7-0.6-0.4-0.3-0.00.2-0.3-0.2
Reaction time trials completed0.91.74.90.3-1.2-0.3-0.30.02.11.8-1.22.2
Reaction time trials AUC0.81.53.8-0.1-1.3-0.5-0.4-0.21.91.7-1.12.0
Run reversals in cocaine runway, females0.50.51.3-0.0-1.1-0.4-0.6-0.81.00.8-0.40.6
Run reversals in cocaine runway, males0.70.72.1-0.60.10.3-1.3-1.4-0.3-0.31.50.2
Latency to leave start box in cocaine runway0.50.51.9-0.5-0.5-1.4-0.7-0.00.50.9-0.80.6
Latency to leave start box in cocaine runway, F0.10.10.30.40.5-0.30.10.60.10.2-0.50.3
Latency to leave start box in cocaine runway, M1.61.53.8-1.2-1.7-1.9-1.3-0.90.81.3-0.80.6
Std. dev. time between licks in bursts0.50.71.61.20.81.30.90.7-0.5-0.80.1-0.6
Total sessions with >9 infusions3.23.98.2-2.02.10.00.60.4-2.9-2.32.8-2.2
Short access day 1 total inactive lever presses4.96.512.5-0.12.52.21.50.8-3.5-3.52.7-3.5
Short access day 10 total inactive lever presses0.30.61.5-1.0-0.7-0.1-0.7-1.2-0.6-0.50.7-0.9
Short access day 1 total infusions1.72.34.8-0.91.60.61.10.7-2.2-2.01.6-1.9
Short access day 10 total infusions2.02.55.6-1.22.00.10.80.8-2.4-1.92.0-1.8
Short access total infusions3.74.89.8-1.52.70.61.31.0-3.1-2.72.7-2.5
Short access day 1 locomotion1.01.22.4-0.21.10.71.00.9-1.5-1.31.0-1.4
Short access day 10 total locomotion1.22.14.60.61.51.02.11.8-1.6-1.50.6-1.6
Short access total locomotion1.82.14.2-0.41.70.51.41.3-2.1-1.71.2-1.8
One hour access (0.3 mA shock)3.03.58.41.32.81.92.32.9-1.1-1.31.3-0.2
Compulsive drug intake0.30.31.40.7-0.11.2-0.1-0.70.4-0.20.50.5
One hour access (shock baseline)1.01.65.60.51.90.51.62.4-0.9-0.70.5-0.4
Social response proportion0.60.72.80.60.8-0.51.01.7-0.6-0.2-0.6-0.6
Social responses0.60.72.00.31.40.81.00.8-0.7-0.90.7-0.5
Social time2.02.75.71.82.21.82.42.4-0.7-1.10.1-0.4
Soleus weight0.31.03.1-0.10.81.80.5-0.3-0.8-1.21.5-0.6
Bone: stiffness1.11.94.9-1.11.1-0.20.20.0-2.2-1.71.2-2.2
Tibialis anterior weight1.34.510.33.22.52.52.83.0-0.0-0.6-0.50.6
Time to tail flick, vehicle, before self-admin0.20.20.5-0.30.10.50.2-0.1-0.5-0.60.6-0.7
Time to tail flick, vehicle, after self-admin0.20.20.90.9-0.50.80.1-0.50.3-0.1-0.2-0.2
Time to tail flick, test, before self-admin0.20.20.7-0.30.2-0.5-0.3-0.20.40.6-0.10.8
Time to tail flick, test, after self-admin0.20.20.50.5-0.30.20.20.10.70.5-0.50.6
Delta time to tail flick, vehicle, before/after SA0.30.30.50.70.60.50.50.4-0.6-0.60.3-0.6
Delta time to tail flick, test, before/after SA0.70.82.21.5-0.60.90.70.61.00.5-1.00.6
Tibia length0.51.33.4-1.0-0.0-0.2-1.1-1.5-1.3-1.11.8-1.1
Ambulatory time before self-admin0.60.92.31.21.31.01.31.5-0.3-0.4-0.20.0
Ambulatory time after self-admin0.91.12.71.10.71.60.90.4-0.9-1.40.5-1.1
Bone: tissue strength0.40.41.2-0.8-0.7-0.8-0.9-1.10.00.10.4-0.1
Total heroin consumption0.60.72.0-0.31.30.50.50.4-1.0-1.01.4-0.6
Bone: trabecular number0.30.50.7-0.4-0.8-0.5-0.8-0.60.80.8-0.50.7
Bone: trabecular spacing1.62.14.7-1.20.90.2-0.0-0.7-2.0-1.92.2-1.9
Bone: trabecular thickness0.81.03.20.3-0.6-0.80.00.91.11.3-1.81.0
Bone: trabecular tissue density0.81.24.62.10.10.81.01.30.60.3-1.60.1
Water consumed over 24 hours0.40.51.1-0.10.41.10.0-0.4-0.8-1.01.1-0.7
Number of responses in last shaping day4.85.310.80.83.21.23.13.3-2.3-2.11.1-1.8