Hub : Genes

Pcyt2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr10_105891801_105892120 0.11 0.12 1.4e-04 0.05 0.04 0.04 0.05 2.0e-05 1.3e-04 5.4e-05 2.0e-05
2 Liver alternative polyA XM_039087005.1 0.03 0.02 9.5e-04 0.01 0.02 0.01 0.02 8.0e-03 3.3e-03 1.1e-02 2.6e-03
3 Liver mRNA stability Pcyt2 0.07 0.05 1.1e-07 0.07 0.07 0.07 0.07 1.2e-08 6.2e-08 1.9e-08 1.5e-08
4 Brain isoform ratio XM_006247935.4 0.07 0.07 2.7e-04 0.04 0.03 0.04 0.03 1.7e-04 5.0e-04 1.6e-04 4.8e-04
5 Brain isoform ratio NM_053568.2 0.04 0.05 7.7e-03 0.01 0.01 0.01 0.01 4.4e-02 3.5e-02 2.9e-02 3.5e-02
6 Adipose gene expression Pcyt2 0.07 0.06 1.0e-04 0.03 0.04 0.04 0.04 1.8e-04 4.8e-05 5.9e-05 5.3e-05
7 Liver intron excision ratio chr10_105891315_105892120 0.17 0.11 5.8e-09 0.08 0.07 0.07 0.07 1.5e-09 1.8e-08 4.5e-08 2.8e-08
8 Liver intron excision ratio chr10_105893820_105894322 0.16 0.09 0.0e+00 0.17 0.16 0.16 0.16 1.3e-18 7.4e-17 1.3e-17 7.0e-18
9 Liver intron excision ratio chr10_105893861_105894322 0.15 0.08 5.6e-17 0.16 0.15 0.15 0.15 1.9e-17 6.5e-16 4.5e-16 8.3e-17
10 Liver alternative polyA XM_039087005.1 0.03 0.02 7.3e-04 0.02 0.03 0.01 0.02 9.0e-04 7.4e-04 1.9e-02 3.4e-03
11 Brain intron excision ratio chr10_105891315_105892120 0.14 0.1 1.3e-07 0.07 0.07 0.08 0.07 2.4e-07 2.1e-07 1.1e-07 2.3e-07
12 PL isoform ratio XM_006247935.4 0.05 0.03 1.1e-06 0.06 0.06 0.06 0.06 3.8e-07 3.1e-07 6.3e-07 7.9e-07
13 NAcc intron excision ratio chr10_105891315_105891748 0.04 0.02 6.3e-05 0.01 0.03 0.02 0.02 7.9e-03 3.2e-04 8.1e-04 1.3e-03
14 NAcc alternative polyA XM_039087005.1 0.03 0.03 6.4e-03 0.02 0.01 0.01 0.01 1.2e-03 1.3e-02 1.9e-02 7.1e-03
15 PL isoform ratio NM_053568.2 0.05 0.04 7.1e-05 0.02 0.04 0.03 0.03 2.9e-03 7.9e-05 2.0e-04 4.2e-04
16 Liver gene expression Pcyt2 0.02 0.02 9.7e-03 0.01 0.01 0 0.01 3.4e-02 2.4e-02 1.5e-01 2.4e-02
17 PL intron excision ratio chr10_105891315_105892120 0.04 0.03 2.2e-04 0.02 0.03 0.03 0.02 3.3e-03 3.6e-04 2.9e-04 1.4e-03
18 Liver isoform ratio XR_005489961.1 0.09 0.06 8.0e-05 0.01 0.02 0.03 0.01 3.9e-02 1.3e-03 5.8e-04 8.0e-03
19 NAcc isoform ratio XM_006247935.4 0.02 0.02 3.8e-03 0.03 0.02 0.02 0.02 5.8e-04 1.3e-03 2.5e-03 1.6e-03
20 NAcc intron excision ratio chr10_105891315_105892120 0.04 0.02 5.1e-05 0.04 0.04 0.04 0.04 1.1e-05 1.2e-05 1.9e-05 1.6e-05
21 OFC isoform ratio XM_039087004.1 0.32 0.2 6.4e-04 0.1 0.01 0.11 0.11 1.8e-03 1.4e-01 1.5e-03 1.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.20.30.8-0.4-0.3-0.5-0.70.6-0.5-0.70.7-0.7-0.7-0.90.4-0.30.5-0.30.9-0.30.9-0.5-0.5-0.2
Area under the delay curve1.81.93.11.51.31.41.7-1.61.51.5-1.51.51.41.7-1.41.3-1.31.3-1.21.2-1.11.11.10.4
BMI with tail0.72.24.8-1.1-1.3-1.6-1.10.4-1.3-1.71.7-1.7-1.7-1.51.3-1.11.4-1.21.9-1.21.8-1.4-1.4-2.2
BMI without tail6.513.522.9-2.7-3.1-3.7-2.42.1-2.9-4.14.1-4.1-4.4-3.43.4-2.74.4-3.24.8-2.64.6-4.2-4.2-4.3
Body weight4.318.223.0-4.7-4.6-4.8-4.54.2-4.4-4.64.6-4.6-4.5-4.64.2-4.04.1-3.93.9-3.83.9-4.1-4.1-2.9
Weight adjusted by age2.83.15.8-2.3-2.2-2.4-1.51.4-2.0-2.02.0-2.0-1.7-1.81.8-1.81.4-1.71.3-2.01.1-1.2-1.2-1.6
Bone surface0.30.51.3-0.9-0.6-0.7-1.11.1-0.8-0.80.8-0.8-0.7-1.00.6-0.60.5-0.50.5-0.50.6-0.6-0.60.4
Bone volume0.30.50.9-0.7-0.6-0.7-0.90.9-0.8-0.80.8-0.8-0.8-0.90.6-0.50.5-0.50.8-0.50.8-0.6-0.6-0.1
Breakpoint value in progressive ratio session0.40.41.4-0.4-1.0-0.60.8-0.5-0.9-0.40.4-0.4-0.30.30.8-1.00.1-0.9-0.2-1.2-0.4-0.1-0.1-1.1
Number of licking bursts0.30.41.5-0.6-0.1-0.5-1.21.0-0.3-0.60.6-0.6-0.5-1.10.1-0.00.40.00.80.20.8-0.3-0.30.3
Context. condit. distance diff. score0.81.03.6-0.5-0.6-1.0-0.20.2-0.3-1.01.0-1.0-1.2-0.80.5-0.11.1-0.31.9-0.21.9-1.0-1.0-1.9
Locomotion velocity, session 12.93.15.71.61.52.01.8-1.41.52.0-2.02.02.12.1-1.41.1-1.81.2-2.40.8-2.41.61.61.9
Locomotion distance, session 12.53.24.92.12.21.81.9-1.82.11.8-1.81.81.61.7-2.12.2-1.62.1-0.82.2-0.81.61.60.6
Locomotion velocity, session 25.16.07.42.42.42.72.3-1.82.52.7-2.72.72.62.7-2.52.3-2.52.4-2.42.4-2.32.52.51.9
Locomotion distance, session 20.30.51.20.80.90.61.0-0.61.00.6-0.60.60.40.6-0.81.0-0.30.90.21.10.20.20.2-0.1
Locomotion velocity, session 32.12.43.41.51.41.71.4-1.41.31.7-1.71.71.81.6-1.51.3-1.71.4-1.81.1-1.81.61.61.4
Locomotion distance, session 33.63.95.12.12.02.12.3-2.11.92.1-2.12.12.12.1-2.01.9-2.12.0-1.71.8-1.72.02.01.0
Stereotopy head waving bouts, day 30.70.81.40.70.81.00.7-0.60.71.0-1.01.01.10.8-0.80.6-1.00.7-1.20.8-1.10.90.91.2
Stereotopy head waving duration, day 30.40.40.60.50.60.70.4-0.40.60.7-0.70.70.80.6-0.70.6-0.80.6-0.70.8-0.70.70.70.7
Locomotion velocity, session 70.70.81.21.00.90.90.8-1.00.90.9-0.90.90.90.9-1.01.0-1.11.1-0.61.0-0.51.01.0-0.1
Locomotion distance, session 72.63.35.32.22.11.72.0-2.22.31.7-1.71.71.51.8-2.12.3-1.72.2-0.52.1-0.51.71.7-0.4
Stereotopy head waving bouts, day 70.20.20.8-0.4-0.5-0.5-0.00.1-0.5-0.50.5-0.5-0.4-0.30.4-0.40.3-0.30.4-0.10.4-0.4-0.4-0.9
Stereotopy head waving duration, day 70.40.40.8-0.9-0.9-0.7-0.70.8-0.8-0.70.7-0.7-0.6-0.70.6-0.70.5-0.50.4-0.30.5-0.6-0.6-0.4
Locomotion velocity, session 80.40.51.20.90.80.60.8-0.71.10.6-0.60.60.30.8-0.81.1-0.20.80.41.10.40.30.3-0.5
Locomotion distance, session 80.61.04.80.10.0-0.60.4-0.30.4-0.60.6-0.6-1.0-0.4-0.10.70.80.32.20.62.2-0.8-0.8-2.1
Degree of sensitization distance0.80.81.8-0.6-0.7-0.9-0.90.7-0.4-0.90.9-0.9-1.1-0.80.7-0.51.0-0.71.3-0.61.2-0.9-0.9-1.2
Degree of sensitization stereotypy0.50.61.7-0.6-0.8-0.8-0.20.3-0.7-0.80.8-0.8-0.8-0.50.7-0.60.7-0.60.8-0.60.8-0.8-0.8-1.3
Conditioned locomotion5.26.18.1-2.3-2.2-2.6-2.52.3-2.1-2.62.6-2.6-2.7-2.72.3-2.02.6-2.22.7-2.02.7-2.8-2.8-1.8
Cocaine response after cond. corrected0.20.20.60.50.30.40.6-0.80.10.4-0.40.40.30.50.0-0.1-0.2-0.1-0.6-0.3-0.70.30.30.2
Cocaine response after cond. not corrected0.60.71.11.10.91.01.0-1.00.70.9-0.90.90.81.0-0.60.5-0.70.5-1.00.3-1.00.80.80.7
Cocaine response before conditioning0.80.92.20.91.11.00.7-0.31.10.9-0.90.90.90.8-1.21.3-0.91.3-0.41.5-0.31.01.00.8
Saline control response3.44.55.1-2.2-2.2-2.2-2.22.2-2.2-2.32.3-2.3-2.2-2.22.1-2.02.3-2.01.9-1.81.9-2.2-2.2-1.2
Bone: connectivity density0.10.10.6-0.10.2-0.1-0.30.50.2-0.10.1-0.1-0.2-0.4-0.30.40.10.40.70.50.8-0.1-0.10.3
Bone: cortical apparent density2.83.74.72.12.12.12.0-2.21.92.1-2.12.12.11.9-1.91.8-2.11.8-1.91.5-1.91.81.81.2
Bone: cortical area6.59.913.6-3.5-3.4-3.4-3.73.5-3.7-3.43.4-3.4-3.1-3.43.2-3.22.9-3.12.4-2.92.4-2.8-2.8-1.1
Bone: cortical porosity0.70.82.4-1.0-1.2-0.6-0.90.7-1.4-0.50.5-0.5-0.2-0.51.2-1.50.4-1.3-0.9-1.4-1.0-0.2-0.20.5
Bone: cortical porosity0.90.92.5-1.2-1.3-0.9-1.00.8-1.5-0.80.8-0.8-0.5-0.71.3-1.60.6-1.4-0.5-1.4-0.5-0.4-0.40.1
Bone: cortical thickness5.18.312.5-3.3-3.2-3.0-3.43.3-3.5-3.13.1-3.1-2.7-3.03.1-3.32.6-3.11.6-3.11.7-2.6-2.6-0.5
Bone: cortical thickness1.72.02.9-1.5-1.5-1.5-1.61.4-1.7-1.51.5-1.5-1.3-1.51.6-1.61.3-1.50.9-1.50.9-1.2-1.2-0.7
Bone: cortical tissue density3.34.35.42.22.32.22.2-2.32.02.2-2.22.22.32.0-2.11.9-2.32.0-2.11.6-2.12.02.01.3
Condit. Reinf. active minus inactive responses2.52.83.5-1.6-1.8-1.8-1.31.4-1.7-1.81.8-1.8-1.9-1.51.8-1.61.8-1.71.7-1.61.6-1.8-1.8-1.6
Condit. Reinf. active-inactive response ratio1.01.11.4-1.0-1.1-1.2-0.80.6-1.1-1.21.2-1.2-1.2-1.01.1-1.01.0-1.11.1-1.11.0-1.0-1.0-1.2
Condit. Reinf. active responses4.65.77.0-2.3-2.4-2.5-2.22.3-2.3-2.52.5-2.5-2.6-2.22.4-2.22.6-2.42.4-2.02.3-2.6-2.6-1.9
Condit. Reinf. inactive responses1.31.52.3-1.2-1.3-1.2-1.11.3-1.1-1.21.2-1.2-1.4-1.01.3-1.11.5-1.31.2-0.91.2-1.5-1.5-1.1
Incentive salience index mean2.02.53.1-1.6-1.7-1.7-1.41.5-1.5-1.71.7-1.7-1.7-1.51.5-1.41.7-1.41.7-1.21.7-1.6-1.6-1.4
Condit. Reinf. lever presses0.10.10.5-0.1-0.1-0.2-0.20.30.0-0.20.2-0.2-0.3-0.2-0.20.30.10.30.60.50.7-0.0-0.0-0.5
Condit. Reinf. active minus inactive responses1.01.32.1-1.2-1.2-1.2-0.91.3-0.9-1.01.0-1.0-1.2-0.91.2-1.11.3-1.21.1-1.10.9-1.4-1.4-0.6
Condit. Reinf. active-inactive response ratio2.52.64.5-1.9-1.9-1.6-1.72.1-1.6-1.51.5-1.5-1.6-1.41.8-1.81.7-1.91.0-1.70.9-1.9-1.9-0.3
Condit. Reinf. active responses0.30.40.9-0.3-0.5-0.60.10.2-0.2-0.50.5-0.5-0.7-0.20.6-0.50.8-0.70.8-0.70.6-0.9-0.9-0.8
Condit. Reinf. inactive responses0.60.72.51.20.90.81.5-1.61.00.7-0.70.70.61.0-0.70.8-0.70.7-0.20.6-0.30.60.6-0.4
Condit. Reinf. lever presses0.30.41.5-0.2-0.4-0.70.0-0.3-0.2-0.50.5-0.5-0.7-0.40.5-0.30.7-0.41.0-0.50.8-0.8-0.8-1.2
Condit. Reinf. lever reinforcers received0.30.41.5-0.2-0.5-0.60.3-0.2-0.1-0.50.5-0.5-0.8-0.20.6-0.40.8-0.61.0-0.70.8-0.9-0.9-1.2
Conditioned reinforcement - actives0.20.21.3-0.50.1-0.5-1.10.6-0.0-0.20.2-0.2-0.3-1.0-0.20.30.10.30.60.60.7-0.2-0.20.3
Conditioned reinforcement - inactives1.51.73.1-1.8-1.7-1.7-1.31.5-1.4-1.11.1-1.1-1.3-1.11.4-1.41.3-1.40.9-1.50.7-1.1-1.1-0.7
Conditioned locomotion0.20.31.4-1.1-0.5-0.8-1.21.1-0.3-0.20.2-0.2-0.3-0.90.1-0.10.10.10.40.10.4-0.1-0.10.1
Patch foraging indifference point 0 sec0.10.10.3-0.3-0.4-0.5-0.0-0.4-0.5-0.40.4-0.4-0.3-0.30.3-0.30.2-0.30.3-0.40.4-0.5-0.5-0.5
Patch foraging indifference point AUC0.00.00.20.20.30.20.1-0.10.20.1-0.10.1-0.10.10.10.00.2-0.10.2-0.10.0-0.4-0.40.3
Delay disc. indifference point, 0s delay0.10.10.3-0.0-0.1-0.10.6-0.50.20.2-0.20.20.20.3-0.30.2-0.40.3-0.10.3-0.10.20.2-0.5
Delay disc. indifference point, 16s delay1.61.63.41.31.30.81.6-1.81.71.2-1.21.21.11.2-1.61.7-1.11.6-0.31.6-0.21.01.0-0.3
Delay disc. indifference point, 2s delay0.50.61.70.60.30.51.3-0.90.60.9-0.90.90.71.2-0.60.5-0.70.6-0.70.6-0.70.60.6-0.5
Delay disc. indifference point, 24s delay5.75.56.92.32.22.42.1-2.22.32.6-2.62.62.62.5-2.32.1-2.62.2-2.51.9-2.42.42.41.7
Delay disc. indifference point, 4s delay0.50.60.90.80.91.00.9-0.60.70.8-0.80.80.80.8-0.70.6-0.60.6-0.70.8-0.60.60.60.9
Delay disc. indifference point, 8s delay1.01.01.71.10.91.21.1-0.90.91.2-1.21.21.11.3-0.80.6-1.10.6-1.30.4-1.20.70.70.8
Indifference point function ln k0.81.11.91.11.10.91.1-1.31.01.0-1.01.01.10.9-1.21.2-1.11.2-0.71.1-0.71.41.40.2
Indifference point function log k0.81.11.91.11.10.91.1-1.31.01.0-1.01.01.10.9-1.21.2-1.11.2-0.71.1-0.71.41.40.2
Patch foraging total patch changes 0 sec0.10.20.5-0.2-0.4-0.60.2-0.6-0.4-0.40.4-0.4-0.4-0.20.3-0.30.2-0.30.4-0.40.5-0.5-0.5-0.7
Patch foraging total patch changes 12 sec0.00.10.20.1-0.10.00.3-0.3-0.20.0-0.00.0-0.10.20.3-0.30.1-0.3-0.1-0.3-0.2-0.4-0.40.1
Patch foraging total patch changes 18 sec0.20.21.70.60.50.01.0-1.30.50.2-0.20.2-0.00.3-0.20.4-0.00.30.40.10.3-0.2-0.2-0.4
Patch foraging total patch changes 24 sec0.60.81.5-0.9-0.9-1.2-0.70.2-0.9-0.90.9-0.9-1.0-1.00.9-0.80.8-0.80.9-0.90.9-0.9-0.9-0.8
Patch foraging total patch changes 6 sec0.30.50.9-0.8-0.8-0.7-0.60.6-0.9-0.60.6-0.6-0.6-0.60.8-0.80.7-0.80.3-0.60.3-0.8-0.80.1
Patch foraging time to switch 0 sec0.50.71.10.70.80.80.6-0.60.80.9-0.90.90.90.7-0.90.8-0.90.9-0.80.9-0.91.01.00.7
Patch foraging water rate 0 sec2.43.95.0-1.8-2.1-2.2-1.11.0-1.7-2.12.1-2.1-2.2-1.62.0-1.82.1-1.92.2-1.82.1-2.2-2.2-2.2
Patch foraging water rate 12 sec0.30.52.3-0.3-0.5-0.80.3-0.3-0.1-0.60.6-0.6-0.8-0.30.5-0.20.9-0.41.2-0.31.1-0.5-0.5-1.5
Patch foraging water rate 18 sec0.81.12.8-0.8-0.9-1.2-0.60.6-0.6-1.21.2-1.2-1.2-1.10.6-0.41.2-0.51.7-0.31.7-0.8-0.8-1.6
Patch foraging water rate 24 sec2.23.19.3-1.3-1.5-2.1-0.60.2-1.2-1.91.9-1.9-2.1-1.61.5-1.12.1-1.32.6-1.12.4-1.7-1.7-3.0
Patch foraging water rate 6 sec0.10.20.7-0.4-0.5-0.60.2-0.0-0.1-0.40.4-0.4-0.5-0.20.2-0.10.6-0.10.8-0.10.7-0.3-0.3-0.8
Seeking ratio, delayed vs. immediate footshock1.71.92.9-1.2-1.0-1.2-1.61.6-1.4-1.51.5-1.5-1.5-1.71.4-1.31.6-1.31.4-1.21.4-1.4-1.4-0.3
Distance traveled before self-admin1.11.23.0-1.0-1.4-1.0-0.90.6-1.5-1.11.1-1.1-0.9-0.71.4-1.50.6-1.40.2-1.70.1-0.8-0.8-1.1
Distance traveled after self-admin0.60.71.4-0.4-0.7-0.9-0.0-0.1-0.7-1.01.0-1.0-1.0-0.60.7-0.60.9-0.71.1-0.61.1-0.9-0.9-1.2
Extensor digitorum longus weight0.20.64.00.0-0.0-0.6-0.1-0.20.1-0.70.7-0.7-0.9-0.60.10.30.60.11.70.21.6-0.7-0.7-2.0
Bone: elastic displacement1.31.52.8-1.3-1.2-1.2-1.71.3-1.6-1.31.3-1.3-1.1-1.51.3-1.41.1-1.30.6-1.30.7-1.0-1.0-0.3
Bone: elastic work6.68.513.8-3.1-3.3-2.9-3.12.8-3.7-3.13.1-3.1-2.6-2.83.4-3.62.7-3.51.2-3.61.2-2.6-2.6-0.7
Bone: endosteal estimation0.10.20.80.10.1-0.20.1-0.10.2-0.30.3-0.3-0.4-0.3-0.10.30.20.20.90.20.9-0.1-0.1-0.9
Bone: endosteal perimeter0.71.52.9-1.4-1.3-1.3-1.71.6-1.4-1.41.4-1.4-1.2-1.51.2-1.21.0-1.11.0-1.11.1-0.9-0.9-0.3
Epididymis fat weight1.22.73.9-1.7-1.6-1.9-1.71.2-1.6-1.91.9-1.9-1.9-2.01.4-1.31.6-1.32.0-1.31.9-1.3-1.3-1.6
Delta time in closed arm before/after self-admin0.40.42.7-0.80.1-0.3-1.61.60.20.2-0.20.20.1-0.8-0.40.4-0.10.40.20.60.2-0.2-0.21.1
Delta time in open arm before/after self-admin0.30.32.20.2-0.2-0.30.9-1.2-0.0-0.30.3-0.3-0.10.2-0.00.1-0.10.10.3-0.10.30.10.1-1.5
Diff in mean of infusions in LGA sessions0.40.41.30.40.40.40.9-0.90.30.5-0.50.50.70.5-0.60.4-0.80.6-0.70.3-0.71.11.10.3
Delay discount exponential model param2.62.84.2-1.9-1.7-1.8-2.01.8-1.7-1.91.9-1.9-1.7-2.01.6-1.51.6-1.51.6-1.41.5-1.4-1.4-0.9
Extinction: sum of active levers before priming1.91.93.81.10.81.11.5-1.71.01.2-1.21.21.61.6-1.31.1-1.81.3-1.60.9-1.52.02.0-0.1
Active lever presses in extinction session 60.90.82.40.2-0.40.11.5-1.30.10.7-0.70.70.91.4-0.30.1-1.10.3-1.2-0.2-1.51.21.2-0.9
Bone: final force5.99.511.8-3.3-3.4-3.4-2.92.9-3.4-3.43.4-3.4-3.2-3.13.3-3.23.1-3.22.5-3.02.5-3.0-3.0-2.0
Bone: final moment6.710.914.0-3.5-3.6-3.6-3.23.1-3.7-3.63.6-3.6-3.4-3.33.5-3.53.2-3.42.5-3.32.5-3.1-3.1-2.1
Food consumed during 24 hour testing period0.60.84.9-0.8-1.4-1.0-0.20.5-0.8-0.80.8-0.8-0.8-0.10.7-0.70.7-0.60.7-0.50.7-0.8-0.8-2.2
Glucose3.85.715.42.21.72.62.5-2.61.72.6-2.62.62.83.0-1.40.9-2.41.1-3.80.3-3.92.22.21.8
Heart weight0.40.51.0-0.4-0.7-0.6-0.10.2-0.7-0.90.9-0.9-0.8-0.50.9-0.90.8-0.90.6-1.00.5-0.7-0.7-0.8
Delay discount hyperbolic model param2.52.74.3-1.8-1.6-1.7-2.11.8-1.7-1.81.8-1.8-1.7-2.01.5-1.51.6-1.41.5-1.41.4-1.4-1.4-0.7
Intermittent access intake day 1-15 change0.90.81.4-0.8-0.9-0.8-0.91.0-1.0-0.80.8-0.8-0.9-0.71.2-1.11.0-1.20.6-1.10.5-1.1-1.1-0.6
Intermittent access intake escalation0.80.81.1-0.8-0.9-0.9-0.91.0-0.9-0.80.8-0.8-1.0-0.71.0-0.91.0-1.00.7-0.80.7-1.1-1.1-0.8
Intermittent access intake escalation 21.81.83.3-1.6-1.7-1.4-1.11.4-1.8-1.21.2-1.2-1.2-1.01.7-1.81.1-1.70.5-1.80.4-1.2-1.2-0.9
Intermitt. access day 1 inactive lever presses1.21.23.1-1.2-1.8-1.3-0.20.6-1.2-1.01.0-1.0-1.0-0.31.3-1.41.1-1.40.6-1.60.4-0.9-0.9-1.4
Intermitt. access day 15 inactive lever presses1.51.62.8-1.5-1.4-1.7-1.51.3-1.0-1.31.3-1.3-1.3-1.31.0-0.91.2-0.91.4-0.81.4-1.2-1.2-1.4
Intermitt. access escalation Index1.41.22.6-1.2-0.9-1.4-1.31.1-0.6-1.11.1-1.1-1.2-1.30.6-0.41.1-0.51.5-0.21.6-1.2-1.2-1.0
Intermittent access day 1 total infusions0.40.40.7-0.4-0.4-0.4-0.60.5-0.6-0.70.7-0.7-0.8-0.80.7-0.60.8-0.70.7-0.60.7-0.8-0.8-0.0
Intermittent access day 15 total infusions0.91.01.3-1.0-0.9-1.0-1.11.0-0.9-1.01.0-1.0-1.1-1.01.0-0.91.1-0.91.1-0.71.0-1.1-1.1-0.7
Intermittent access terminal intake (last 3 days)1.51.62.6-1.4-1.2-1.3-1.61.5-1.3-1.21.2-1.2-1.3-1.51.3-1.31.3-1.31.1-1.11.1-1.3-1.3-0.5
Intermittent access total infusions0.70.81.1-0.8-0.7-0.8-1.11.0-0.8-0.90.9-0.9-1.0-1.00.9-0.81.0-0.81.0-0.60.9-1.1-1.1-0.4
Intermittent access day 1 locomotion0.50.51.0-1.0-0.7-1.0-0.80.8-0.5-0.60.6-0.6-0.8-0.90.5-0.40.7-0.40.9-0.30.8-0.7-0.7-0.5
Intermittent access day 15 total locomotion0.50.51.4-0.9-0.7-0.7-0.81.2-0.8-0.50.5-0.5-0.7-0.70.8-0.80.7-0.80.5-0.60.4-0.8-0.80.2
Intermittent access total locomotion0.60.71.5-1.2-1.0-1.0-1.01.2-0.8-0.60.6-0.6-0.8-0.80.7-0.70.8-0.70.7-0.60.6-0.8-0.8-0.4
Intermittent access standard deviation0.50.52.10.50.00.60.8-0.60.00.6-0.60.60.81.1-0.2-0.1-1.00.1-1.4-0.2-1.40.90.9-0.1
Left kidney weight0.10.31.8-0.7-0.4-0.2-0.91.2-0.6-0.20.2-0.2-0.0-0.60.2-0.40.0-0.2-0.30.0-0.1-0.1-0.11.3
Right kidney weight0.10.32.7-0.50.10.0-0.91.0-0.10.0-0.00.00.2-0.6-0.20.1-0.20.3-0.20.4-0.00.20.21.6
Cocaine induced anxiety3.64.212.6-2.2-2.9-2.1-1.01.3-2.7-1.91.9-1.9-1.8-1.02.7-3.01.5-2.80.5-3.50.2-1.3-1.3-1.4
Post-drug Anxiety0.50.53.2-0.5-1.0-0.50.2-0.0-0.9-0.40.4-0.4-0.40.21.0-1.20.4-1.1-0.3-1.8-0.4-0.3-0.3-0.3
Baseline Anxiety6.87.311.92.83.32.91.7-2.13.22.9-2.92.92.72.0-3.23.3-2.53.1-1.83.5-1.62.32.32.3
Tail length6.519.825.2-4.6-4.4-4.8-4.24.6-4.1-4.74.7-4.7-4.9-4.54.2-3.85.0-4.04.7-3.44.6-4.9-4.9-3.0
Length with tail2.910.517.9-4.2-3.6-3.6-4.04.2-3.6-3.33.3-3.3-3.1-3.63.2-3.23.0-3.02.3-2.92.4-2.9-2.9-0.7
Length without tail0.61.26.4-0.6-0.10.4-0.60.8-0.20.8-0.80.81.30.2-0.4-0.1-1.40.4-2.1-0.2-2.01.31.32.5
Times rat made contact with spout1.01.22.9-1.3-1.7-1.0-0.61.1-1.4-0.90.9-0.9-0.7-0.31.3-1.50.9-1.4-0.1-1.4-0.1-1.2-1.2-0.9
Lifetime Intake0.20.20.7-0.5-0.4-0.4-0.80.7-0.4-0.40.4-0.4-0.5-0.60.4-0.40.5-0.40.5-0.20.5-0.6-0.6-0.1
Liver weight, left0.20.31.50.20.10.50.2-0.3-0.00.5-0.50.50.70.5-0.1-0.2-0.7-0.0-1.2-0.4-1.20.60.60.7
Liver weight, right2.23.68.9-2.7-2.4-2.2-2.73.0-2.1-1.81.8-1.8-1.7-2.01.7-1.71.6-1.51.4-1.41.3-1.5-1.5-0.4
Locomotor activity0.71.11.51.01.11.01.2-1.21.01.0-1.01.01.10.9-1.11.0-1.21.1-0.90.9-0.91.11.10.6
Locomotor testing distance0.81.42.31.01.30.81.1-1.51.21.1-1.11.11.20.7-1.41.4-1.31.5-0.71.4-0.71.51.50.4
Locomotor testing rearing0.30.51.10.60.70.40.9-1.00.80.6-0.60.60.60.5-0.80.9-0.70.9-0.20.8-0.30.90.9-0.2
Locomotion in novel chamber0.20.20.80.30.30.00.5-0.90.70.3-0.30.30.40.4-0.60.6-0.60.6-0.00.20.10.30.3-0.3
Locomotion in novel chamber post-restriction2.53.04.4-1.3-1.4-1.2-1.92.0-1.7-1.91.9-1.9-1.9-1.71.9-1.82.1-2.01.5-1.71.5-1.9-1.9-0.2
Fecal boli incidents, locomotor time 10.50.61.00.80.80.80.6-0.70.90.9-0.90.90.70.7-0.91.0-0.81.0-0.41.0-0.30.50.50.3
Change in fecal boli incidents, locomotor task2.72.65.51.71.72.01.9-1.51.11.5-1.51.51.71.5-1.00.7-1.50.8-2.10.6-2.11.71.72.4
Time >=10cm from walls, locomotor time 11.01.03.1-0.3-0.0-0.4-1.20.9-0.3-1.21.2-1.2-1.1-1.30.5-0.31.1-0.51.4-0.21.7-1.4-1.40.1
Bouts of movement, locomotor time 12.02.23.01.61.51.61.5-1.71.51.5-1.51.51.61.5-1.51.4-1.31.4-1.41.3-1.41.71.71.1
Total resting periods, locomotor time 12.42.73.61.71.71.91.5-1.61.51.7-1.71.71.81.7-1.61.4-1.51.5-1.71.4-1.71.81.81.4
Rest time, locomotor task time 10.30.31.00.30.20.50.2-0.10.20.7-0.70.70.70.7-0.30.2-0.50.3-0.90.2-1.00.80.80.6
Distance moved, locomotor task time 10.70.71.3-0.8-0.5-0.8-1.00.8-0.7-1.11.1-1.1-0.9-1.10.7-0.60.9-0.61.0-0.61.0-0.7-0.7-0.7
Vertical activity count, locomotor time 11.51.63.5-1.3-1.1-1.5-1.31.0-0.8-1.51.5-1.5-1.3-1.50.8-0.61.1-0.71.6-0.71.7-0.9-0.9-1.9
Time >=10cm from walls, locomotor time 20.20.31.3-0.30.20.1-1.01.10.0-0.10.1-0.1-0.2-0.80.0-0.00.2-0.00.30.30.5-0.5-0.51.1
Bouts of movement, locomotor time 21.31.42.51.51.21.31.5-1.61.41.3-1.31.31.11.5-1.21.2-1.01.2-0.81.2-0.70.80.80.5
Total resting periods, locomotor time 20.80.91.51.11.00.91.0-1.21.21.0-1.01.00.81.0-1.11.2-0.71.1-0.41.2-0.30.60.60.4
Rest time, locomotor task time 20.10.10.30.30.30.5-0.10.00.20.2-0.20.20.30.2-0.30.2-0.10.3-0.30.4-0.20.50.50.6
Distance moved, locomotor task time 20.00.10.2-0.5-0.1-0.4-0.30.4-0.1-0.10.1-0.1-0.2-0.40.1-0.10.1-0.10.2-0.20.1-0.2-0.2-0.1
Vertical activity count, locomotor time 20.30.31.0-0.6-0.3-0.7-0.60.50.0-0.40.4-0.4-0.5-0.80.00.10.20.10.90.11.0-0.5-0.5-0.8
Light reinforcement 11.42.55.4-1.3-1.1-1.7-1.81.1-1.2-1.91.9-1.9-1.8-2.01.1-0.81.5-0.92.2-0.82.3-1.5-1.5-1.5
Light reinforcement 22.63.55.3-2.0-1.8-2.0-2.22.1-1.8-2.22.2-2.2-2.0-2.31.5-1.41.7-1.32.0-1.12.2-1.7-1.7-1.3
Bone: marrow area0.10.10.80.10.1-0.20.1-0.20.2-0.20.2-0.2-0.4-0.3-0.10.30.20.20.90.20.9-0.1-0.1-0.9
Bone: maximum diameter1.73.26.1-2.1-1.9-1.9-2.52.4-2.0-2.02.0-2.0-1.7-2.21.6-1.61.5-1.51.4-1.31.6-1.4-1.4-0.3
Bone: maximum force6.010.312.1-3.3-3.5-3.4-3.03.1-3.4-3.53.5-3.5-3.4-3.23.4-3.33.3-3.32.8-3.12.7-3.2-3.2-1.9
Bone: maximum moment6.711.613.8-3.6-3.7-3.6-3.23.2-3.7-3.73.7-3.7-3.5-3.43.7-3.63.5-3.62.8-3.42.7-3.4-3.4-2.0
Mean time between licks in bursts1.62.23.31.71.81.61.3-1.41.61.6-1.61.61.51.3-1.71.7-1.51.6-1.01.7-1.01.61.61.0
Mean num. licks in bursts0.30.41.4-0.2-1.0-0.30.8-0.4-0.6-0.10.1-0.1-0.10.80.7-0.90.2-0.8-0.5-1.0-0.6-0.4-0.4-1.2
Cd content in liver2.02.24.41.81.41.52.1-2.01.71.5-1.51.51.32.0-1.41.5-1.31.4-0.91.3-1.01.31.3-0.7
Co content in liver0.20.20.80.40.20.30.8-0.90.30.3-0.30.30.40.6-0.50.5-0.50.6-0.20.6-0.10.50.5-0.9
Cu content in liver0.20.31.2-0.7-1.1-0.4-0.30.5-0.9-0.30.3-0.3-0.00.10.6-0.80.2-0.6-0.6-0.7-0.5-0.1-0.1-0.2
Fe content in liver1.01.21.61.21.21.01.2-1.21.21.1-1.11.11.11.0-1.21.2-1.21.3-0.71.0-0.71.21.20.2
K content in liver2.62.64.3-1.8-1.6-1.8-1.81.9-1.5-1.71.7-1.7-1.8-1.81.2-1.01.5-1.01.9-0.62.1-1.6-1.6-0.9
Mg content in liver0.60.62.6-0.5-0.1-0.7-0.90.9-0.1-0.60.6-0.6-0.8-1.00.00.30.70.21.50.51.6-0.8-0.8-0.3
Mn content in liver0.30.41.0-0.8-0.7-0.6-0.81.0-0.6-0.60.6-0.6-0.5-0.60.6-0.60.6-0.60.3-0.40.4-0.5-0.50.3
Na content in liver0.00.00.2-0.3-0.2-0.2-0.40.4-0.2-0.10.1-0.10.0-0.2-0.10.0-0.10.1-0.10.10.00.20.20.4
Rb content in liver1.11.42.8-0.9-0.9-1.2-1.01.0-0.8-1.21.2-1.2-1.4-1.21.0-0.81.4-0.91.6-0.81.7-1.4-1.4-1.1
Se content in liver0.40.50.9-0.6-0.4-0.7-0.90.7-0.6-0.70.7-0.7-0.7-1.00.6-0.50.7-0.60.7-0.50.8-0.9-0.9-0.1
Sr content in liver0.50.52.10.20.40.5-0.1-0.2-0.10.5-0.50.50.80.2-0.0-0.3-0.7-0.1-1.5-0.4-1.40.60.61.4
Zn content in liver0.20.21.9-0.30.00.1-0.81.0-0.00.2-0.20.20.2-0.2-0.20.2-0.10.3-0.30.6-0.2-0.0-0.01.4
Bone: minimum diameter3.36.29.2-2.8-2.8-2.8-2.82.6-3.0-2.82.8-2.8-2.5-2.72.5-2.52.1-2.41.9-2.22.0-2.1-2.1-1.4
Time in familiar zone, hab. session 10.10.10.30.30.20.30.3-0.40.10.3-0.30.30.20.40.1-0.2-0.0-0.2-0.5-0.5-0.60.00.00.2
Time in novel zone, hab. session 10.00.00.1-0.2-0.1-0.20.2-0.0-0.0-0.20.2-0.2-0.1-0.1-0.10.10.10.10.30.40.4-0.1-0.1-0.3
Total zone transitions, hab. session 10.30.51.20.90.70.61.1-1.10.80.6-0.60.60.50.8-0.70.8-0.50.7-0.10.7-0.20.60.6-0.5
Total locomotion distance, hab. session 10.20.32.80.0-0.3-0.50.3-0.5-0.2-0.50.5-0.5-0.5-0.20.10.10.20.00.90.10.9-0.2-0.2-1.7
Locomotion velocity, hab. session 10.20.32.7-0.0-0.3-0.60.1-0.4-0.2-0.60.6-0.6-0.5-0.30.10.10.20.00.90.11.0-0.2-0.2-1.7
Time in familiar zone, hab. session 20.30.31.10.70.60.40.7-1.00.60.4-0.40.40.40.5-0.50.6-0.40.5-0.10.4-0.10.40.4-0.9
Time in novel zone, hab. session 20.10.11.0-0.00.20.2-0.00.30.20.2-0.20.20.20.1-0.20.2-0.10.2-0.20.3-0.20.10.11.0
Total zone transitions, hab. session 20.30.40.90.70.70.30.8-0.60.90.3-0.30.3-0.10.4-0.61.00.10.70.90.90.9-0.1-0.1-1.0
Total locomotion distance, hab. session 20.70.93.7-0.4-0.4-0.9-0.20.4-0.2-0.90.9-0.9-1.2-0.80.30.10.9-0.11.90.31.9-0.9-0.9-1.8
Locomotion velocity, hab. session 21.01.34.4-0.7-0.7-1.2-0.50.7-0.5-1.21.2-1.2-1.4-1.00.6-0.21.2-0.42.10.02.1-1.2-1.2-1.9
Novel to familiar place preference ratio2.42.54.5-1.6-2.0-1.6-1.21.1-2.0-1.61.6-1.6-1.4-1.22.0-2.11.6-2.00.6-2.10.5-1.5-1.5-0.8
Novelty place preference2.32.34.3-1.6-1.9-1.5-1.21.2-1.9-1.51.5-1.5-1.4-1.11.9-2.11.5-2.00.5-2.00.4-1.4-1.4-0.6
Time in novel zone, NPP test1.91.93.5-1.4-1.7-1.4-1.01.0-1.7-1.41.4-1.4-1.3-1.01.8-1.91.4-1.80.5-1.80.5-1.3-1.3-0.7
Total zone transitions, NPP test0.50.72.00.91.00.40.9-0.81.20.4-0.40.40.10.3-1.01.4-0.21.21.01.41.00.10.1-0.8
Total locomotion distance, NPP test0.50.73.60.10.1-0.50.2-0.20.4-0.50.5-0.5-0.8-0.5-0.30.70.50.51.90.81.9-0.5-0.5-1.7
Locomotion velocity, NPP test0.50.73.2-0.1-0.1-0.70.0-0.00.0-0.70.7-0.7-0.9-0.60.00.30.70.11.80.41.8-0.7-0.7-1.6
Intraocular pressure0.60.91.8-0.6-0.8-0.9-0.30.7-0.7-0.80.8-0.8-1.2-0.71.0-0.91.3-1.11.2-0.81.0-1.3-1.3-0.7
Delta distance traveled before/after self-admin0.40.41.10.70.80.31.0-1.00.90.3-0.30.30.20.3-0.71.0-0.20.80.51.10.50.40.40.0
Delta ambulatory time before/after self-admin1.01.12.81.11.40.81.3-1.21.51.0-1.01.00.80.7-1.31.5-0.71.4-0.01.7-0.00.90.90.7
Parametrial fat weight2.03.97.0-2.2-1.9-2.1-2.72.2-2.0-2.12.1-2.1-1.9-2.31.9-1.91.9-1.81.6-2.01.6-2.0-2.0-0.9
Pavlov. Cond. lever latency0.81.13.41.51.40.81.3-1.91.40.8-0.80.80.40.8-1.11.4-0.51.10.51.10.30.50.5-1.2
Pavlov. Cond. magazine entry latency2.02.55.1-1.8-2.0-1.5-1.41.6-2.1-1.51.5-1.5-1.3-1.22.0-2.21.5-2.10.3-2.20.2-1.6-1.6-0.2
Pavlov. Cond. change in total contacts0.20.20.8-0.4-0.6-0.2-0.10.2-0.8-0.20.2-0.20.1-0.00.6-0.9-0.0-0.7-0.8-0.9-0.8-0.0-0.00.3
Pavlov. Cond. index score2.93.65.8-2.3-2.3-1.9-2.12.4-2.4-1.91.9-1.9-1.6-1.82.1-2.31.7-2.10.7-2.10.8-1.7-1.7-0.1
Pavlov. Cond. latency score2.22.75.4-2.1-2.1-1.6-1.92.3-2.2-1.61.6-1.6-1.3-1.51.8-2.11.4-1.90.3-1.90.4-1.4-1.40.3
Pavlov. Cond. lever contacts0.70.82.4-1.3-1.1-0.8-1.21.6-1.2-0.80.8-0.8-0.6-0.90.9-1.00.5-0.80.0-0.80.1-0.5-0.50.7
Pavlov. Cond. magazine entry number1.72.15.31.61.81.21.3-1.41.91.2-1.21.20.90.9-1.92.2-1.22.00.32.30.31.31.3-0.2
Pavlov. Cond. intertrial magazine entries0.40.51.6-0.4-0.3-0.7-0.80.6-0.2-0.70.7-0.7-0.9-0.80.4-0.20.8-0.31.2-0.21.2-0.7-0.7-1.1
Pavlov. Cond. lever-magazine prob. diff.3.03.75.8-2.3-2.3-2.0-2.12.3-2.4-2.02.0-2.0-1.7-1.82.2-2.31.7-2.20.7-2.20.8-1.7-1.7-0.2
Pavlov. Cond. response bias1.62.04.0-1.7-1.8-1.3-1.51.7-1.9-1.31.3-1.3-1.0-1.11.7-2.01.2-1.8-0.0-1.9-0.0-1.2-1.20.3
Pavlov. Cond. lever latency0.71.03.40.60.71.10.30.00.51.0-1.01.01.20.8-0.70.5-1.00.7-1.50.6-1.41.11.11.8
Pavlov. Cond. magazine entry latency1.61.94.11.71.61.21.7-2.01.71.2-1.21.21.01.3-1.61.7-1.11.6-0.21.7-0.31.31.3-0.5
Pavlov. Cond. change in total contacts0.30.42.30.80.60.11.0-1.50.70.2-0.20.20.00.4-0.40.6-0.20.50.50.30.40.10.1-1.2
Pavlov. Cond. index score0.30.31.90.70.5-0.00.9-1.40.60.2-0.20.2-0.00.3-0.40.6-0.10.40.60.40.40.10.1-1.3
Pavlov. Cond. latency score0.20.31.80.50.4-0.10.8-1.20.50.1-0.10.1-0.10.2-0.30.6-0.00.40.70.40.60.00.0-1.4
Pavlov. Cond. lever contacts1.11.54.1-0.8-0.9-1.3-0.50.2-0.6-1.31.3-1.3-1.5-1.10.9-0.61.3-0.81.8-0.81.7-1.4-1.4-2.0
Pavlov. Cond. magazine entry number1.11.43.9-1.5-1.4-0.8-1.52.0-1.4-1.01.0-1.0-0.8-1.01.3-1.51.0-1.4-0.0-1.40.0-1.0-1.00.7
Pavlov. Cond. intertrial magazine entries2.02.63.6-1.7-1.6-1.6-1.61.8-1.4-1.61.6-1.6-1.7-1.61.7-1.61.9-1.71.4-1.61.4-1.9-1.9-0.6
Pavlov. Cond. lever-magazine prob. diff.0.40.52.50.80.60.11.2-1.60.70.3-0.30.30.10.5-0.50.7-0.30.60.50.50.30.30.3-1.3
Pavlov. Cond. response bias0.30.32.50.1-0.1-0.50.4-0.70.1-0.40.4-0.4-0.6-0.20.20.10.5-0.11.1-0.10.9-0.5-0.5-1.6
Time in closed arm before self-admin0.30.41.11.00.40.91.0-1.00.10.3-0.30.30.50.90.0-0.2-0.3-0.1-0.9-0.2-0.80.40.40.2
Time in closed arm after self-admin0.90.92.90.60.61.20.30.10.51.1-1.11.11.11.1-0.40.1-0.90.3-1.70.0-1.70.80.81.6
Time in open arm before self-admin0.30.41.5-0.60.3-0.2-1.01.10.30.3-0.30.30.2-0.7-0.60.7-0.20.70.20.90.20.30.31.2
Time in open arm after self-admin0.10.20.50.30.40.00.5-0.60.40.0-0.00.00.1-0.0-0.60.7-0.30.70.30.70.40.30.3-0.3
Bone: periosteal estimation2.24.55.9-2.2-2.1-2.3-2.42.2-2.3-2.42.4-2.4-2.3-2.42.1-1.92.0-1.92.0-1.82.1-1.9-1.9-1.2
Bone: periosteal perimeter3.25.38.8-2.7-2.6-2.3-3.02.9-2.9-2.42.4-2.4-2.0-2.52.5-2.61.9-2.41.1-2.41.2-1.9-1.9-0.0
Bone: post-yield work0.00.10.30.20.2-0.00.2-0.00.4-0.00.0-0.0-0.2-0.0-0.20.30.10.20.60.20.5-0.2-0.2-0.3
Progressive ratio test 1 active lever presses1.31.42.0-1.2-1.1-1.2-1.31.2-1.2-1.31.3-1.3-1.3-1.41.1-1.01.3-1.01.3-1.01.3-1.2-1.2-0.6
Progressive ratio test 1 breakpoint1.81.82.4-1.3-1.2-1.3-1.51.3-1.3-1.51.5-1.5-1.5-1.61.3-1.21.4-1.31.4-1.21.4-1.4-1.4-0.7
Progressive ratio test 1 inactive lever presses3.03.24.4-1.9-2.0-2.1-1.61.4-1.7-2.02.0-2.0-1.9-1.71.7-1.61.8-1.61.9-1.61.8-1.7-1.7-2.0
Progressive ratio test 2 active lever presses0.50.61.6-0.8-0.6-0.6-1.11.3-0.7-0.50.5-0.5-0.8-0.90.8-0.70.8-0.70.6-0.60.6-0.9-0.90.2
Progressive ratio test 2 breakpoint0.70.81.9-0.9-0.6-0.8-1.21.4-0.7-0.70.7-0.7-0.9-1.00.8-0.71.0-0.70.9-0.50.9-1.1-1.1-0.1
Progressive ratio test 2 inactive lever presses0.40.51.0-0.9-0.8-0.8-0.81.0-0.8-0.60.6-0.6-0.7-0.70.8-0.80.7-0.80.4-0.80.3-0.7-0.7-0.2
Incentive Sensitization - Responses0.30.31.0-0.4-0.2-0.2-0.71.0-0.4-0.30.3-0.3-0.6-0.50.6-0.50.7-0.60.4-0.60.3-0.9-0.90.4
Incentive Sensitization - Breakpoint0.20.20.9-0.3-0.2-0.2-0.60.9-0.3-0.20.2-0.2-0.4-0.40.5-0.50.6-0.60.3-0.50.2-0.8-0.80.5
Sum of active levers in priming session hrs 5-60.90.82.3-0.2-1.0-0.71.5-1.2-0.9-0.50.5-0.5-0.60.51.1-1.20.5-1.30.1-1.5-0.2-0.7-0.7-1.5
Progressive ratio0.50.60.90.70.60.70.9-0.80.70.9-0.90.90.81.0-0.80.8-0.70.8-0.70.7-0.80.70.70.1
Food seeking constrained by brief footshock0.30.41.50.6-0.00.61.1-0.80.20.5-0.50.50.61.2-0.30.1-0.60.2-0.9-0.1-0.80.40.4-0.7
Seeking ratio, punishment vs. effort0.20.20.5-0.3-0.5-0.4-0.20.1-0.4-0.60.6-0.6-0.5-0.30.5-0.40.4-0.40.5-0.30.6-0.5-0.5-0.7
Retroperitoneal fat weight5.016.420.7-4.2-4.1-4.5-4.33.3-4.2-4.64.6-4.6-4.2-4.54.0-3.83.9-3.73.8-3.93.9-3.7-3.7-3.2
Reaction time number correct0.81.15.60.10.3-0.80.2-0.80.6-0.80.8-0.8-1.0-1.0-0.30.90.70.52.40.92.4-0.6-0.6-1.8
Reaction time mean minus median0.20.20.9-0.00.10.3-0.00.1-0.00.4-0.40.40.60.2-0.20.0-0.70.2-0.9-0.1-0.90.80.80.8
Reaction time mean minus median AUC0.10.10.6-0.6-0.3-0.2-0.60.8-0.10.0-0.00.00.1-0.3-0.0-0.1-0.20.1-0.3-0.0-0.30.30.30.6
Reaction time num false alarms0.20.31.00.70.70.50.6-1.00.50.5-0.50.50.60.5-0.60.6-0.50.5-0.50.7-0.40.60.6-0.0
Reaction time num false alarms AUC0.60.81.51.01.10.80.8-1.11.00.9-0.90.90.90.8-1.01.0-0.81.0-0.61.2-0.61.01.00.3
Reaction time trials correct on left0.81.15.60.10.3-0.80.2-0.80.6-0.80.8-0.8-1.0-1.0-0.30.90.70.52.40.92.4-0.6-0.6-1.8
Reaction time trials on left0.81.25.80.10.3-0.90.1-0.70.6-0.80.8-0.8-1.0-1.0-0.30.90.70.62.40.92.4-0.6-0.6-1.8
Reaction time mean0.30.40.8-0.8-0.6-0.8-0.70.4-0.5-0.70.7-0.7-0.6-0.90.5-0.50.4-0.50.7-0.80.6-0.5-0.5-0.5
Reaction time mean AUC0.30.41.1-0.7-0.4-0.9-0.80.4-0.4-0.70.7-0.7-0.7-1.10.3-0.30.4-0.20.9-0.40.9-0.4-0.4-0.5
Median of all reaction times0.30.50.9-0.7-0.5-0.9-0.60.4-0.5-0.80.8-0.8-0.8-0.90.5-0.40.6-0.50.9-0.70.8-0.6-0.6-0.7
Reaction time omissions0.20.30.8-0.7-0.4-0.9-0.70.3-0.3-0.50.5-0.5-0.4-0.80.10.00.00.10.7-0.00.8-0.1-0.1-0.9
Reaction time false alarm rate0.81.13.00.80.71.10.7-0.70.51.2-1.21.21.31.2-0.70.5-1.10.6-1.70.6-1.61.11.11.0
Reaction time premature initiation rate1.52.04.41.71.51.52.1-1.61.41.6-1.61.61.41.8-1.21.2-1.21.1-1.21.3-1.21.01.00.6
Reaction time premature initiations0.91.33.61.61.50.91.9-1.81.60.9-0.90.90.61.0-1.21.5-0.61.20.21.60.20.50.5-0.4
Std. dev. reaction times0.30.40.70.40.60.40.5-0.70.70.6-0.60.60.70.4-0.70.6-0.80.7-0.50.4-0.50.80.80.2
Reaction time trials completed0.81.25.80.10.3-0.90.1-0.70.6-0.80.8-0.8-1.0-1.0-0.30.90.70.62.40.92.4-0.6-0.6-1.8
Reaction time trials AUC0.81.25.90.00.3-0.90.1-0.70.6-0.90.9-0.9-1.1-1.1-0.30.80.70.52.40.82.4-0.6-0.6-1.9
Run reversals in cocaine runway, females0.80.73.51.41.10.81.6-1.91.00.4-0.40.40.40.8-0.81.0-0.70.80.10.80.30.20.2-0.3
Run reversals in cocaine runway, males1.11.12.4-1.3-1.3-0.9-1.11.4-1.4-0.80.8-0.8-0.8-0.81.3-1.50.8-1.40.1-1.5-0.1-0.9-0.90.0
Latency to leave start box in cocaine runway0.30.30.70.80.80.60.3-0.60.60.5-0.50.50.40.3-0.60.7-0.20.6-0.00.8-0.10.40.40.3
Latency to leave start box in cocaine runway, F0.40.41.80.50.90.30.2-0.40.70.4-0.40.40.2-0.1-0.91.1-0.11.00.51.30.40.50.50.5
Latency to leave start box in cocaine runway, M0.10.10.20.1-0.10.2-0.40.4-0.2-0.10.1-0.1-0.20.00.4-0.40.3-0.5-0.1-0.4-0.1-0.4-0.4-0.0
Std. dev. time between licks in bursts1.11.35.3-0.5-0.4-1.1-0.60.3-0.2-1.11.1-1.1-1.4-1.20.30.11.1-0.12.30.12.3-1.1-1.1-1.8
Total sessions with >9 infusions0.30.31.10.10.60.4-0.60.40.50.5-0.50.50.4-0.1-0.60.6-0.40.6-0.20.8-0.10.40.41.1
Short access day 1 total inactive lever presses0.20.20.7-0.6-0.0-0.5-0.60.60.20.0-0.00.0-0.2-0.7-0.40.50.30.50.70.80.7-0.1-0.10.1
Short access day 10 total inactive lever presses3.43.85.3-1.9-2.3-1.9-1.52.0-2.0-1.91.9-1.9-2.1-1.42.3-2.22.2-2.31.5-2.21.3-2.0-2.0-1.5
Short access day 1 total infusions1.71.82.51.11.31.30.8-0.91.31.5-1.51.51.51.1-1.51.4-1.51.5-1.21.4-1.21.61.61.0
Short access day 10 total infusions0.50.50.8-0.8-0.8-0.7-0.80.8-0.9-0.70.7-0.7-0.8-0.70.9-0.90.7-0.90.5-0.90.4-0.8-0.8-0.2
Short access total infusions0.00.00.2-0.00.10.1-0.40.3-0.00.1-0.10.1-0.0-0.2-0.0-0.00.00.00.00.00.0-0.1-0.10.2
Short access day 1 locomotion0.50.61.90.30.70.80.00.10.50.7-0.70.70.90.4-0.70.5-0.90.7-1.00.6-0.91.01.01.4
Short access day 10 total locomotion0.20.20.9-0.1-0.10.30.30.3-0.00.6-0.60.60.50.5-0.1-0.1-0.50.0-0.9-0.2-1.00.50.50.5
Short access total locomotion0.50.51.40.30.50.8-0.00.30.50.9-0.90.90.80.5-0.60.4-0.70.5-1.00.5-1.00.80.81.2
One hour access (0.3 mA shock)1.72.02.7-1.3-1.2-1.4-1.61.4-1.3-1.51.5-1.5-1.6-1.61.4-1.21.6-1.31.5-1.11.6-1.6-1.6-0.6
Compulsive drug intake0.60.62.3-0.5-0.9-0.9-0.3-0.0-0.6-0.90.9-0.9-0.8-0.40.6-0.60.7-0.60.8-0.70.8-0.6-0.6-1.5
One hour access (shock baseline)0.40.52.3-0.8-0.3-0.6-1.51.4-0.3-0.50.5-0.5-0.6-1.20.3-0.20.7-0.20.80.10.8-0.7-0.70.5
Social response proportion0.30.40.80.60.60.40.9-0.70.90.7-0.70.70.50.6-0.70.8-0.60.7-0.20.7-0.30.40.4-0.1
Social responses0.10.10.50.10.30.00.1-0.30.30.1-0.10.10.30.0-0.60.6-0.40.70.10.60.20.40.4-0.5
Social time0.10.10.40.30.50.2-0.1-0.20.30.1-0.10.10.2-0.1-0.50.5-0.30.50.10.60.20.50.5-0.1
Soleus weight1.54.56.0-2.3-2.3-2.3-2.52.3-2.1-2.32.3-2.3-2.2-2.22.0-1.92.2-1.92.0-1.62.1-2.2-2.2-1.3
Bone: stiffness0.81.31.6-1.2-1.2-1.3-0.91.1-1.1-1.21.2-1.2-1.3-1.11.1-1.01.2-1.11.2-1.01.1-1.2-1.2-0.7
Tibialis anterior weight0.00.20.8-0.2-0.2-0.2-0.40.50.0-0.40.4-0.4-0.5-0.30.10.10.4-0.00.90.10.9-0.4-0.4-0.6
Time to tail flick, vehicle, before self-admin0.10.10.2-0.2-0.3-0.10.00.2-0.2-0.30.3-0.3-0.3-0.10.2-0.10.3-0.10.40.10.4-0.4-0.4-0.2
Time to tail flick, vehicle, after self-admin2.32.54.31.51.91.70.8-0.91.61.6-1.61.61.61.1-1.81.8-1.51.8-1.22.1-1.11.81.81.7
Time to tail flick, test, before self-admin0.10.10.4-0.2-0.30.00.20.6-0.20.1-0.10.1-0.20.30.5-0.40.5-0.6-0.1-0.3-0.2-0.4-0.40.2
Time to tail flick, test, after self-admin0.30.40.6-0.20.10.10.10.20.50.8-0.80.80.70.4-0.70.6-0.70.7-0.60.6-0.70.80.80.5
Delta time to tail flick, vehicle, before/after SA0.30.31.00.40.70.3-0.1-0.20.80.6-0.60.60.50.1-0.80.9-0.40.8-0.01.0-0.00.70.70.4
Delta time to tail flick, test, before/after SA0.70.71.30.40.70.60.5-0.80.50.8-0.80.81.00.5-0.80.6-1.10.8-1.00.4-1.01.11.10.9
Tibia length9.225.935.8-5.9-5.6-5.3-6.05.7-5.8-5.25.2-5.2-4.8-5.35.6-5.75.0-5.62.9-5.43.0-4.9-4.9-0.7
Ambulatory time before self-admin2.22.34.2-1.5-2.0-1.6-1.10.9-2.0-1.71.7-1.7-1.4-1.11.8-2.01.1-1.80.7-2.00.7-1.2-1.2-1.5
Ambulatory time after self-admin0.40.40.9-0.5-0.7-0.8-0.1-0.0-0.6-0.80.8-0.8-0.7-0.50.6-0.50.5-0.50.8-0.50.8-0.6-0.6-1.0
Bone: tissue strength1.61.52.7-1.2-1.1-1.4-1.21.2-1.1-1.41.4-1.4-1.4-1.41.0-0.81.3-0.91.6-0.51.6-1.1-1.1-1.2
Total heroin consumption0.30.41.2-0.2-0.7-0.30.8-0.8-0.50.0-0.00.00.30.60.2-0.5-0.6-0.2-0.8-0.7-0.90.80.8-1.1
Bone: trabecular number0.00.10.4-0.20.0-0.1-0.40.6-0.1-0.10.1-0.1-0.1-0.40.0-0.00.1-0.00.2-0.10.2-0.1-0.10.6
Bone: trabecular spacing0.60.85.60.1-0.1-0.70.1-0.40.0-0.70.7-0.7-1.0-0.60.10.30.70.11.90.41.9-0.6-0.6-2.4
Bone: trabecular thickness0.50.61.4-0.8-0.9-0.5-0.70.8-1.0-0.40.4-0.4-0.1-0.30.9-1.20.3-1.0-0.7-1.2-0.8-0.5-0.50.8
Bone: trabecular tissue density0.91.31.51.21.21.21.2-1.21.21.2-1.21.21.21.2-1.21.1-1.11.1-1.01.0-1.01.11.10.6
Water consumed over 24 hours0.10.20.8-0.2-0.50.20.40.1-0.10.3-0.30.30.50.7-0.1-0.1-0.40.1-0.90.2-0.90.30.3-0.1
Number of responses in last shaping day1.21.33.0-1.7-1.4-1.6-1.71.6-1.0-1.01.0-1.0-1.0-1.30.8-0.80.8-0.71.0-0.81.0-0.8-0.8-0.9