Hub : Genes

Pcnx3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_006230948.5 0.02 0.01 6.2e-03 0.01 0.01 0.01 0.01 5.7e-03 6.9e-03 3.3e-02 2.1e-02
2 Adipose mRNA stability Pcnx3 0.24 0.11 4.7e-04 0 0.03 0.03 0.01 2.9e-01 3.8e-04 2.7e-04 2.1e-02
3 NAcc gene expression Pcnx3 0.02 0.02 1.3e-03 0.03 0.01 0.01 0.02 7.9e-06 2.1e-02 1.5e-02 3.4e-04
4 RMTg mRNA stability Pcnx3 0.18 0.12 1.2e-03 0.12 0.12 0.15 0.12 5.2e-04 6.0e-04 9.0e-05 5.0e-04
5 BLA gene expression Pcnx3 0.12 0.07 1.1e-04 0.07 0.07 0.07 0.07 1.3e-04 1.2e-04 1.1e-04 1.1e-04
6 Brain gene expression Pcnx3 0.12 0.07 1.0e-06 0.07 0.06 0.07 0.08 2.1e-07 2.1e-06 2.2e-07 9.6e-08
7 Liver mRNA stability Pcnx3 0.06 0.03 9.5e-05 0.04 0.03 0.02 0.03 4.1e-05 7.5e-04 2.5e-03 3.9e-04
8 PL gene expression Pcnx3 0.05 0.03 9.3e-05 0.03 0.03 0.03 0.03 2.6e-04 2.2e-04 4.7e-04 8.1e-04
9 Adipose gene expression Pcnx3 0.13 0.06 5.2e-09 0.08 0.06 0.07 0.07 2.3e-09 4.8e-07 1.1e-08 1.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.03.44.9-1.9-0.01.91.42.22.2-1.92.11.9
Area under the delay curve0.60.71.2-0.81.10.80.60.80.8-0.30.91.1
BMI with tail5.619.327.3-4.4-0.34.52.25.25.2-5.05.14.9
BMI without tail2.37.011.8-2.40.22.61.13.23.4-2.73.03.3
Body weight2.19.016.2-2.7-2.32.9-0.23.73.2-4.03.23.1
Weight adjusted by age0.20.32.0-0.2-1.40.0-0.60.30.1-0.3-0.1-0.1
Bone surface3.15.78.0-2.8-2.32.50.82.62.4-2.82.42.1
Bone volume2.34.16.4-2.5-1.22.31.42.12.0-2.22.21.8
Breakpoint value in progressive ratio session1.01.23.0-1.4-1.71.4-0.21.01.1-0.80.81.0
Number of licking bursts0.10.10.4-0.5-0.60.50.40.20.1-0.10.20.3
Context. condit. distance diff. score0.40.53.50.51.9-0.30.3-0.20.10.4-0.1-0.0
Locomotion velocity, session 10.30.31.10.8-0.0-0.7-1.1-0.2-0.4-0.0-0.4-0.2
Locomotion distance, session 11.62.13.3-1.20.31.20.61.81.8-1.61.61.8
Locomotion velocity, session 21.82.13.3-1.5-1.01.40.41.81.5-1.71.51.8
Locomotion distance, session 21.21.73.5-1.10.21.10.61.71.5-1.31.51.9
Locomotion velocity, session 31.01.12.8-0.70.80.70.51.30.8-1.71.31.2
Locomotion distance, session 30.00.00.10.10.1-0.1-0.10.1-0.3-0.20.10.2
Stereotopy head waving bouts, day 31.01.22.7-0.31.40.40.41.30.9-1.71.31.0
Stereotopy head waving duration, day 30.40.51.8-0.31.30.30.50.60.5-0.70.70.5
Locomotion velocity, session 72.32.63.6-1.41.41.31.91.71.7-1.41.71.8
Locomotion distance, session 70.70.91.6-0.50.90.50.41.31.2-1.11.11.2
Stereotopy head waving bouts, day 70.50.61.6-1.00.31.01.30.60.6-0.40.70.5
Stereotopy head waving duration, day 71.01.22.5-1.6-0.21.61.01.01.1-0.71.11.1
Locomotion velocity, session 80.40.51.70.7-1.2-0.7-1.30.3-0.1-0.6-0.10.0
Locomotion distance, session 80.70.91.4-0.61.10.70.71.10.9-1.21.11.1
Degree of sensitization distance1.11.12.1-0.70.50.60.51.41.4-1.41.21.0
Degree of sensitization stereotypy0.60.71.8-1.3-0.51.30.90.50.6-0.40.70.6
Conditioned locomotion0.40.51.6-0.3-1.30.3-0.90.60.3-0.90.40.3
Cocaine response after cond. corrected0.30.41.70.91.3-0.9-0.4-0.2-0.2-0.1-0.2-0.3
Cocaine response after cond. not corrected0.20.31.00.81.0-0.8-0.4-0.1-0.2-0.2-0.1-0.2
Cocaine response before conditioning0.20.21.1-0.7-1.10.50.30.10.2-0.00.20.2
Saline control response0.81.14.1-0.4-2.00.3-0.71.11.0-1.30.70.7
Bone: connectivity density2.84.36.4-2.2-1.12.11.02.52.5-2.32.32.0
Bone: cortical apparent density0.30.41.70.2-0.0-0.1-0.3-0.8-0.31.3-0.8-0.2
Bone: cortical area0.20.42.3-0.5-1.50.2-0.10.30.1-0.80.30.1
Bone: cortical porosity0.30.40.6-0.70.20.80.20.70.7-0.50.70.8
Bone: cortical porosity0.50.60.8-0.8-0.20.9-0.10.90.8-0.80.80.9
Bone: cortical thickness0.81.46.80.6-2.6-0.6-1.9-0.5-0.50.3-0.8-0.4
Bone: cortical thickness0.70.82.71.0-1.0-1.0-1.6-0.5-0.50.5-0.8-0.5
Bone: cortical tissue density0.30.41.70.2-0.2-0.1-0.4-0.8-0.31.3-0.8-0.3
Condit. Reinf. active minus inactive responses0.30.40.7-0.60.30.70.80.60.7-0.20.50.8
Condit. Reinf. active-inactive response ratio0.10.10.5-0.20.40.30.4-0.10.20.7-0.10.3
Condit. Reinf. active responses0.60.71.4-0.90.31.01.20.80.8-0.70.91.0
Condit. Reinf. inactive responses0.80.92.0-1.00.20.91.11.00.7-1.41.10.9
Incentive salience index mean1.11.32.1-1.10.41.21.01.31.3-1.11.21.4
Condit. Reinf. lever presses1.01.42.4-1.3-0.31.20.71.31.2-1.51.31.1
Condit. Reinf. active minus inactive responses0.10.21.2-0.5-0.10.31.10.10.10.00.20.0
Condit. Reinf. active-inactive response ratio0.40.42.5-0.70.20.41.60.1-0.3-0.60.5-0.0
Condit. Reinf. active responses0.40.51.5-0.9-0.10.81.20.50.80.10.50.6
Condit. Reinf. inactive responses0.40.51.8-0.60.10.70.20.81.40.20.50.9
Condit. Reinf. lever presses0.91.33.3-1.4-1.81.30.90.90.8-0.90.90.7
Condit. Reinf. lever reinforcers received0.30.51.1-0.9-0.50.81.10.50.70.10.40.5
Conditioned reinforcement - actives0.30.51.20.3-1.1-0.20.2-0.7-1.00.1-0.5-1.0
Conditioned reinforcement - inactives0.91.42.40.80.7-0.70.8-1.4-1.51.4-1.1-1.6
Conditioned locomotion2.93.75.31.91.9-1.61.0-2.3-2.22.3-1.7-2.2
Patch foraging indifference point 0 sec0.00.00.1-0.30.20.2-0.00.20.30.00.20.2
Patch foraging indifference point AUC0.40.63.2-0.7-1.80.8-1.10.0-0.0-0.1-0.10.1
Delay disc. indifference point, 0s delay1.11.24.2-0.72.00.80.80.90.8-0.81.11.4
Delay disc. indifference point, 16s delay0.40.41.4-0.51.10.71.20.10.10.40.30.7
Delay disc. indifference point, 2s delay0.20.20.6-0.50.50.40.80.30.2-0.60.60.4
Delay disc. indifference point, 24s delay0.20.20.40.70.4-0.6-0.5-0.3-0.30.4-0.4-0.1
Delay disc. indifference point, 4s delay0.50.51.6-0.31.30.30.20.70.7-0.60.70.8
Delay disc. indifference point, 8s delay0.30.31.0-0.41.00.4-0.00.60.6-0.10.50.6
Indifference point function ln k1.32.38.51.82.9-1.91.2-0.9-0.80.9-0.7-0.9
Indifference point function log k1.32.38.51.82.9-1.91.2-0.9-0.80.9-0.7-0.9
Patch foraging total patch changes 0 sec0.00.10.40.3-0.0-0.3-0.6-0.1-0.00.3-0.2-0.1
Patch foraging total patch changes 12 sec1.41.82.9-1.4-1.71.7-0.81.31.5-0.91.01.4
Patch foraging total patch changes 18 sec0.40.51.2-1.0-0.61.10.20.70.6-0.60.70.7
Patch foraging total patch changes 24 sec0.30.62.8-0.0-1.7-0.1-1.40.10.2-0.3-0.3-0.1
Patch foraging total patch changes 6 sec0.40.60.8-0.6-0.80.6-0.40.90.9-0.90.70.9
Patch foraging time to switch 0 sec2.75.68.6-2.9-0.42.91.62.62.5-2.32.62.5
Patch foraging water rate 0 sec3.26.710.13.20.8-3.2-0.7-2.9-2.82.5-2.8-2.9
Patch foraging water rate 12 sec4.910.318.54.22.0-4.3-0.6-3.4-3.42.9-3.2-3.4
Patch foraging water rate 18 sec1.52.34.92.21.3-2.1-0.2-1.4-1.50.9-1.3-1.5
Patch foraging water rate 24 sec3.14.37.52.71.6-2.7-0.5-2.2-2.21.5-2.0-2.2
Patch foraging water rate 6 sec3.75.411.33.21.2-3.4-0.7-2.3-2.41.6-2.2-2.4
Seeking ratio, delayed vs. immediate footshock0.60.81.5-0.81.20.81.20.70.80.10.71.0
Distance traveled before self-admin0.71.02.2-1.5-0.61.40.70.90.9-0.70.90.9
Distance traveled after self-admin0.10.10.2-0.4-0.30.3-0.5-0.10.20.5-0.10.1
Extensor digitorum longus weight2.39.217.9-2.7-4.22.8-1.93.32.9-3.72.52.7
Bone: elastic displacement2.42.85.62.4-0.0-2.3-1.3-1.6-1.71.3-1.8-1.7
Bone: elastic work0.50.72.41.0-1.2-0.8-1.6-0.0-0.1-0.1-0.5-0.2
Bone: endosteal estimation1.22.75.4-1.31.41.11.81.81.3-2.32.01.2
Bone: endosteal perimeter1.32.75.7-1.61.31.22.41.61.2-2.11.91.0
Epididymis fat weight0.51.64.00.92.0-1.01.7-1.1-1.30.5-0.5-1.4
Delta time in closed arm before/after self-admin0.30.31.20.60.2-0.5-1.10.50.3-0.60.10.3
Delta time in open arm before/after self-admin0.20.20.7-0.5-0.80.50.2-0.4-0.30.4-0.3-0.3
Diff in mean of infusions in LGA sessions0.10.20.80.1-0.9-0.0-0.90.0-0.1-0.2-0.1-0.1
Delay discount exponential model param0.40.50.90.7-0.9-0.7-0.4-0.7-0.60.3-0.7-1.0
Extinction: sum of active levers before priming2.02.23.3-1.8-0.71.80.41.61.8-1.31.51.7
Active lever presses in extinction session 60.90.94.5-0.9-2.10.8-0.40.40.1-1.20.50.3
Bone: final force1.01.63.4-1.2-1.81.1-0.21.41.0-1.81.10.9
Bone: final moment0.91.53.1-1.1-1.81.1-0.31.31.0-1.81.10.9
Food consumed during 24 hour testing period0.71.01.80.6-0.9-0.8-0.3-1.2-1.31.1-1.1-1.2
Glucose1.21.96.9-0.82.60.71.61.11.0-1.11.51.1
Heart weight2.13.26.6-0.92.61.01.02.01.9-2.02.11.9
Delay discount hyperbolic model param0.50.50.90.8-0.9-0.7-0.5-0.7-0.70.4-0.8-0.9
Intermittent access intake day 1-15 change0.51.11.90.90.4-0.80.1-1.4-1.41.2-1.1-1.4
Intermittent access intake escalation0.61.22.10.90.2-0.80.1-1.4-1.51.1-1.2-1.5
Intermittent access intake escalation 20.91.01.90.70.3-0.7-0.1-1.4-1.41.2-1.1-1.3
Intermitt. access day 1 inactive lever presses0.10.31.20.00.40.1-1.1-0.5-0.40.8-0.5-0.3
Intermitt. access day 15 inactive lever presses0.20.41.6-0.10.80.31.3-0.5-0.80.6-0.2-0.6
Intermitt. access escalation Index0.71.04.20.41.9-0.52.0-0.4-0.20.9-0.1-0.2
Intermittent access day 1 total infusions1.52.510.0-1.01.61.33.21.10.9-1.11.80.8
Intermittent access day 15 total infusions0.81.25.40.61.2-0.22.3-0.9-1.10.5-0.2-1.1
Intermittent access terminal intake (last 3 days)0.81.17.50.01.10.22.7-0.4-0.7-0.10.4-0.7
Intermittent access total infusions1.11.38.7-0.31.00.62.90.3-0.0-0.71.0-0.1
Intermittent access day 1 locomotion0.91.24.7-0.71.40.92.20.60.5-0.61.20.5
Intermittent access day 15 total locomotion0.61.16.30.01.20.32.5-0.7-0.70.60.0-0.8
Intermittent access total locomotion1.72.012.9-0.61.80.93.6-0.1-0.2-0.10.8-0.3
Intermittent access standard deviation0.51.01.81.00.6-0.7-0.4-1.2-1.30.9-1.0-1.3
Left kidney weight0.10.63.2-0.31.80.41.30.10.1-0.20.60.1
Right kidney weight0.10.40.80.60.8-0.50.1-0.7-0.90.2-0.4-0.7
Cocaine induced anxiety0.00.00.1-0.3-0.30.3-0.00.0-0.00.00.00.0
Post-drug Anxiety0.20.21.1-0.5-1.10.2-0.30.40.2-0.50.20.3
Baseline Anxiety0.20.21.10.3-0.6-0.5-1.00.1-0.1-0.2-0.2-0.0
Tail length0.31.13.61.1-1.1-0.9-1.9-0.6-0.70.6-1.0-0.6
Length with tail0.41.67.70.2-2.8-0.1-2.40.4-0.2-0.9-0.20.0
Length without tail0.51.77.70.5-2.8-0.5-2.40.3-0.4-1.0-0.2-0.1
Times rat made contact with spout0.20.20.6-0.30.10.5-0.10.50.60.20.20.8
Lifetime Intake0.91.16.4-0.30.90.62.50.40.2-0.81.00.1
Liver weight, left0.30.51.31.10.8-1.1-0.3-0.4-0.6-0.1-0.4-0.8
Liver weight, right0.61.13.01.71.5-1.5-0.5-0.4-0.7-0.1-0.4-0.9
Locomotor activity1.82.96.42.50.8-2.2-1.2-1.6-1.71.2-1.6-1.7
Locomotor testing distance2.03.78.62.91.1-2.7-1.2-1.8-1.81.3-1.8-1.8
Locomotor testing rearing1.22.45.02.21.4-2.2-1.1-1.3-1.21.3-1.3-1.5
Locomotion in novel chamber1.01.32.71.01.6-0.91.4-1.1-1.20.7-0.6-1.2
Locomotion in novel chamber post-restriction0.61.02.50.51.3-0.31.6-1.1-0.81.1-0.6-0.8
Fecal boli incidents, locomotor time 10.10.20.7-0.6-0.40.60.8-0.2-0.40.3-0.1-0.1
Change in fecal boli incidents, locomotor task0.40.41.20.10.5-0.1-0.40.70.7-1.10.70.7
Time >=10cm from walls, locomotor time 12.12.25.9-1.61.01.72.41.00.9-1.41.61.0
Bouts of movement, locomotor time 10.50.52.0-0.5-0.30.3-1.2-0.5-0.21.4-0.80.0
Total resting periods, locomotor time 10.30.41.5-0.6-0.20.5-0.7-0.4-0.11.2-0.50.1
Rest time, locomotor task time 10.60.81.60.80.8-0.8-0.0-1.1-1.30.8-0.8-1.0
Distance moved, locomotor task time 10.91.31.9-1.1-0.11.01.31.41.4-1.01.31.2
Vertical activity count, locomotor time 10.10.20.60.50.5-0.50.8-0.1-0.10.4-0.2-0.3
Time >=10cm from walls, locomotor time 20.10.20.6-0.70.10.70.50.10.20.20.20.1
Bouts of movement, locomotor time 20.10.20.5-0.7-0.10.6-0.40.10.30.6-0.00.6
Total resting periods, locomotor time 20.10.30.7-0.80.20.7-0.10.20.30.50.10.7
Rest time, locomotor task time 20.40.53.20.31.8-0.20.5-0.7-0.80.3-0.1-0.3
Distance moved, locomotor task time 20.20.21.5-0.1-1.2-0.1-0.50.20.3-0.0-0.20.0
Vertical activity count, locomotor time 21.21.73.21.8-0.9-1.8-1.2-1.1-1.00.9-1.4-1.3
Light reinforcement 10.10.30.80.70.1-0.6-0.4-0.7-0.40.9-0.7-0.6
Light reinforcement 20.30.51.10.2-0.1-0.41.1-0.8-1.00.5-0.5-0.9
Bone: marrow area1.32.95.7-1.41.61.21.91.81.4-2.42.11.3
Bone: maximum diameter0.20.31.4-0.5-1.20.10.10.2-0.2-1.10.4-0.2
Bone: maximum force2.74.87.9-2.5-1.92.30.82.52.1-2.82.31.9
Bone: maximum moment2.54.57.6-2.4-1.82.20.72.42.0-2.82.21.9
Mean time between licks in bursts0.20.41.80.9-0.3-0.8-1.30.10.0-0.3-0.20.0
Mean num. licks in bursts0.10.20.80.40.9-0.2-0.2-0.00.20.5-0.20.0
Cd content in liver0.50.51.4-0.10.50.11.2-0.9-0.71.0-0.4-0.7
Co content in liver3.03.45.52.20.9-2.0-1.4-2.0-1.62.4-2.1-1.6
Cu content in liver0.50.61.2-0.80.61.01.10.40.80.30.50.9
Fe content in liver0.30.41.00.7-1.0-0.7-0.8-0.1-0.5-0.7-0.2-0.5
K content in liver1.11.02.0-0.8-0.10.80.21.31.2-1.41.21.2
Mg content in liver0.30.31.0-0.11.00.20.70.50.5-0.40.50.7
Mn content in liver0.80.94.7-0.9-2.20.70.20.70.5-1.00.60.4
Na content in liver0.60.61.90.6-1.3-0.5-1.4-0.5-0.7-0.0-0.6-0.7
Rb content in liver0.40.42.70.71.6-0.60.5-0.10.10.5-0.10.1
Se content in liver0.20.31.9-0.2-0.30.01.4-0.2-0.30.2-0.0-0.3
Sr content in liver0.70.63.50.0-1.9-0.1-1.1-0.4-0.40.3-0.6-0.4
Zn content in liver0.20.30.9-0.50.10.60.00.50.90.00.30.7
Bone: minimum diameter2.03.76.0-1.91.71.62.41.92.0-1.72.11.7
Time in familiar zone, hab. session 10.40.31.2-0.40.60.31.10.50.6-0.40.60.5
Time in novel zone, hab. session 11.11.12.21.40.1-1.3-1.5-0.9-1.10.7-1.0-1.0
Total zone transitions, hab. session 10.50.71.2-1.0-0.41.10.70.81.1-0.30.71.1
Total locomotion distance, hab. session 10.50.71.3-0.71.10.70.50.80.9-0.80.90.9
Locomotion velocity, hab. session 10.50.71.0-0.80.70.90.30.91.0-0.80.91.0
Time in familiar zone, hab. session 20.70.72.21.3-0.2-1.3-1.5-0.3-0.4-0.2-0.5-0.6
Time in novel zone, hab. session 20.70.71.6-1.20.51.21.30.60.70.10.70.9
Total zone transitions, hab. session 23.74.77.3-2.20.32.21.22.62.7-2.02.42.6
Total locomotion distance, hab. session 22.22.94.1-1.41.41.51.12.01.9-1.71.92.0
Locomotion velocity, hab. session 22.22.93.9-1.51.41.61.31.91.8-1.82.01.9
Novel to familiar place preference ratio0.80.82.4-1.6-0.91.40.90.50.7-0.20.60.5
Novelty place preference0.50.61.8-1.4-0.51.20.90.30.60.00.50.5
Time in novel zone, NPP test0.40.41.3-1.1-0.41.00.80.30.50.00.40.4
Total zone transitions, NPP test1.72.43.7-1.7-0.71.80.31.91.9-1.41.61.8
Total locomotion distance, NPP test1.01.42.3-1.10.81.20.51.41.5-1.11.31.5
Locomotion velocity, NPP test1.01.32.3-1.20.71.30.61.31.5-0.91.21.4
Intraocular pressure1.52.23.71.1-0.0-1.0-0.8-1.9-1.81.7-1.7-1.9
Delta distance traveled before/after self-admin0.90.91.71.30.3-1.2-1.3-0.9-0.70.9-1.0-0.7
Delta ambulatory time before/after self-admin0.70.81.81.20.1-1.1-1.3-0.8-0.60.8-0.9-0.6
Parametrial fat weight0.51.16.6-0.22.60.21.7-0.2-0.40.00.5-0.2
Pavlov. Cond. lever latency0.50.61.00.80.0-0.9-0.5-0.9-0.81.0-0.9-0.9
Pavlov. Cond. magazine entry latency1.41.93.3-1.70.61.81.31.31.4-0.91.31.5
Pavlov. Cond. change in total contacts1.01.02.5-1.60.31.61.50.60.7-0.10.70.9
Pavlov. Cond. index score0.30.30.9-0.9-0.00.90.50.40.5-0.30.50.5
Pavlov. Cond. latency score0.40.50.9-0.90.21.00.60.70.7-0.60.70.7
Pavlov. Cond. lever contacts0.50.61.0-0.80.30.90.50.90.8-1.00.90.9
Pavlov. Cond. magazine entry number0.10.20.70.70.3-0.9-0.40.1-0.1-0.3-0.0-0.2
Pavlov. Cond. intertrial magazine entries0.70.81.70.6-0.1-0.70.6-1.1-1.01.3-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.71.6-1.2-0.01.30.70.70.8-0.50.70.9
Pavlov. Cond. response bias0.10.20.6-0.7-0.20.80.40.10.20.10.20.3
Pavlov. Cond. lever latency0.20.31.80.71.4-0.4-0.2-0.20.10.6-0.30.1
Pavlov. Cond. magazine entry latency2.02.44.0-2.0-1.52.00.31.61.7-1.11.41.7
Pavlov. Cond. change in total contacts1.01.64.5-2.1-1.41.91.20.80.8-0.51.01.0
Pavlov. Cond. index score1.31.73.6-1.9-1.61.70.71.11.0-1.01.11.1
Pavlov. Cond. latency score1.21.63.3-1.8-1.61.60.71.10.9-1.11.11.0
Pavlov. Cond. lever contacts0.20.31.7-0.7-1.30.50.20.2-0.1-0.50.3-0.0
Pavlov. Cond. magazine entry number2.32.95.42.32.3-2.2-0.4-1.5-1.61.0-1.3-1.6
Pavlov. Cond. intertrial magazine entries0.30.40.70.70.7-0.80.1-0.7-0.80.4-0.5-0.8
Pavlov. Cond. lever-magazine prob. diff.1.41.93.9-2.0-1.71.80.71.21.1-1.01.21.2
Pavlov. Cond. response bias0.91.22.3-1.5-1.51.40.40.90.8-0.90.90.9
Time in closed arm before self-admin0.20.31.5-0.70.40.61.20.10.1-0.10.40.1
Time in closed arm after self-admin0.10.10.30.20.5-0.20.50.10.2-0.20.20.1
Time in open arm before self-admin0.60.61.61.31.0-1.2-1.0-0.1-0.00.5-0.50.0
Time in open arm after self-admin0.20.20.90.4-0.1-0.4-1.0-0.3-0.20.5-0.5-0.2
Bone: periosteal estimation0.61.34.0-1.2-0.20.91.01.20.8-2.01.40.8
Bone: periosteal perimeter0.71.12.7-1.2-0.50.91.01.20.8-1.61.30.8
Bone: post-yield work10.214.922.3-4.71.04.44.03.93.9-3.64.23.8
Progressive ratio test 1 active lever presses0.10.10.80.0-0.20.20.9-0.1-0.2-0.10.1-0.3
Progressive ratio test 1 breakpoint0.10.10.8-0.0-0.30.30.9-0.1-0.2-0.10.1-0.3
Progressive ratio test 1 inactive lever presses0.10.10.30.00.10.3-0.4-0.3-0.30.5-0.3-0.3
Progressive ratio test 2 active lever presses0.50.63.20.30.5-0.01.8-0.7-0.80.4-0.1-0.9
Progressive ratio test 2 breakpoint0.60.63.00.40.4-0.11.7-0.7-0.90.4-0.2-0.9
Progressive ratio test 2 inactive lever presses1.32.27.00.72.0-0.42.6-1.3-1.41.5-0.6-1.3
Incentive Sensitization - Responses0.40.62.1-0.7-0.10.81.40.70.5-0.80.80.5
Incentive Sensitization - Breakpoint0.40.52.1-0.60.10.71.50.60.3-0.60.70.3
Sum of active levers in priming session hrs 5-62.52.36.80.6-2.6-0.8-1.0-1.6-1.80.9-1.6-1.8
Progressive ratio3.45.37.5-2.50.32.71.62.62.4-2.42.62.4
Food seeking constrained by brief footshock0.00.00.10.2-0.3-0.20.20.20.1-0.20.10.1
Seeking ratio, punishment vs. effort2.63.76.82.50.3-2.6-1.2-2.0-1.82.0-2.1-1.9
Retroperitoneal fat weight1.56.223.82.64.9-2.41.9-1.9-2.01.6-1.1-2.2
Reaction time number correct0.30.61.20.8-1.0-0.9-1.1-0.6-0.9-0.1-0.6-0.7
Reaction time mean minus median0.61.63.7-1.9-1.71.70.11.00.9-0.90.91.0
Reaction time mean minus median AUC0.20.52.4-0.9-1.50.8-0.60.2-0.0-0.40.20.2
Reaction time num false alarms0.40.51.61.30.7-1.1-1.0-0.2-0.20.2-0.5-0.1
Reaction time num false alarms AUC0.20.31.30.90.3-0.7-1.20.10.1-0.1-0.20.3
Reaction time trials correct on left0.30.61.20.8-1.0-0.9-1.1-0.6-0.9-0.1-0.6-0.7
Reaction time trials on left0.40.71.40.8-1.1-0.9-1.2-0.6-0.9-0.1-0.6-0.7
Reaction time mean0.10.20.7-0.80.10.70.4-0.1-0.20.60.00.2
Reaction time mean AUC0.20.31.0-1.00.31.00.5-0.0-0.00.50.20.4
Median of all reaction times0.20.30.6-0.60.80.60.6-0.2-0.20.7-0.00.2
Reaction time omissions0.40.51.1-1.0-1.10.9-0.50.60.4-0.40.40.7
Reaction time false alarm rate0.20.20.80.60.9-0.4-0.40.20.3-0.1-0.00.4
Reaction time premature initiation rate0.50.73.50.4-1.2-0.4-1.90.60.5-0.70.00.5
Reaction time premature initiations0.81.46.90.8-1.9-0.8-2.60.1-0.0-0.4-0.50.1
Std. dev. reaction times0.20.41.4-1.2-0.81.00.00.30.2-0.00.30.5
Reaction time trials completed0.40.71.40.8-1.1-0.9-1.2-0.6-0.9-0.1-0.6-0.7
Reaction time trials AUC0.30.61.20.8-0.9-0.9-1.1-0.5-0.8-0.2-0.6-0.7
Run reversals in cocaine runway, females2.12.13.3-1.10.51.10.91.71.8-1.71.71.8
Run reversals in cocaine runway, males2.22.23.21.7-0.7-1.7-1.0-1.7-1.80.9-1.6-1.8
Latency to leave start box in cocaine runway1.11.31.7-1.20.81.31.21.11.2-1.01.31.1
Latency to leave start box in cocaine runway, F0.60.71.2-1.00.91.10.90.71.0-0.20.80.9
Latency to leave start box in cocaine runway, M0.60.62.3-0.5-0.30.50.40.80.5-1.50.90.5
Std. dev. time between licks in bursts0.50.72.11.40.1-1.3-1.4-0.3-0.3-0.1-0.5-0.4
Total sessions with >9 infusions1.11.32.9-0.90.01.01.71.21.0-1.31.40.9
Short access day 1 total inactive lever presses0.20.31.50.41.2-0.30.4-0.3-0.50.2-0.0-0.4
Short access day 10 total inactive lever presses0.10.30.90.40.9-0.3-0.6-0.4-0.40.7-0.4-0.2
Short access day 1 total infusions0.71.03.6-0.41.30.61.90.60.5-0.91.10.5
Short access day 10 total infusions3.03.810.3-1.80.72.03.21.81.6-1.82.31.5
Short access total infusions1.41.84.4-0.90.61.12.11.31.1-1.71.71.0
Short access day 1 locomotion0.50.64.0-0.11.00.32.00.10.1-0.20.50.0
Short access day 10 total locomotion0.40.83.0-0.81.11.01.70.50.4-0.40.90.4
Short access total locomotion0.70.84.3-0.61.00.72.10.40.4-0.40.80.3
One hour access (0.3 mA shock)1.31.53.21.21.8-0.81.6-1.2-1.30.9-0.5-1.3
Compulsive drug intake0.70.95.10.9-0.6-1.0-2.3-0.1-0.10.4-0.8-0.0
One hour access (shock baseline)1.01.55.60.61.7-0.22.4-1.1-1.20.8-0.3-1.2
Social response proportion0.20.20.8-0.6-0.90.5-0.10.30.2-0.10.20.2
Social responses0.20.30.70.4-0.8-0.3-0.8-0.3-0.40.2-0.4-0.5
Social time0.30.41.70.5-0.7-0.5-1.3-0.3-0.60.1-0.5-0.6
Soleus weight0.92.67.91.72.8-1.60.7-1.4-1.61.3-1.0-1.5
Bone: stiffness2.23.66.0-2.4-1.42.20.92.01.8-2.01.91.8
Tibialis anterior weight2.17.037.2-1.3-6.11.2-3.41.60.8-2.60.70.8
Time to tail flick, vehicle, before self-admin0.70.71.0-0.9-0.10.80.91.00.8-1.01.00.8
Time to tail flick, vehicle, after self-admin2.73.55.4-1.70.81.80.82.22.1-2.32.22.1
Time to tail flick, test, before self-admin1.51.64.8-0.52.20.72.00.91.0-0.71.21.0
Time to tail flick, test, after self-admin0.10.10.20.0-0.4-0.2-0.3-0.3-0.3-0.1-0.2-0.4
Delta time to tail flick, vehicle, before/after SA0.90.91.4-0.80.40.9-0.21.11.1-1.21.11.2
Delta time to tail flick, test, before/after SA3.43.56.51.1-2.5-1.4-2.5-1.8-1.81.4-2.0-1.9
Tibia length0.41.28.4-0.8-2.90.50.2-0.4-0.7-0.4-0.2-0.6
Ambulatory time before self-admin0.61.02.3-1.5-0.61.40.90.80.8-0.60.90.8
Ambulatory time after self-admin0.20.30.5-0.70.60.70.6-0.00.40.50.20.3
Bone: tissue strength0.10.10.7-0.40.10.40.80.30.2-0.10.30.3
Total heroin consumption1.11.22.3-1.3-1.51.2-1.21.01.0-0.80.61.1
Bone: trabecular number1.82.94.2-2.1-0.71.91.71.91.9-1.61.91.6
Bone: trabecular spacing0.50.61.11.01.0-0.8-1.0-0.7-0.60.8-0.7-0.4
Bone: trabecular thickness0.50.61.3-0.80.80.81.10.70.9-0.40.80.7
Bone: trabecular tissue density1.52.23.01.41.6-1.40.3-1.7-1.71.6-1.4-1.6
Water consumed over 24 hours0.10.20.60.0-0.80.1-0.5-0.2-0.00.7-0.40.2
Number of responses in last shaping day0.20.30.90.6-0.1-0.5-1.0-0.4-0.40.3-0.5-0.4