Hub : Genes

Pcnx3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_219515.10 0.05 0.04 2.1e-03 0.03 0.01 0.02 0.02 5.4e-04 1.7e-02 9.4e-03 5.4e-03
2 Liver mRNA stability Pcnx3 0.05 0.03 1.3e-04 0.02 0.02 0.02 0.02 3.0e-03 1.2e-03 2.6e-03 3.0e-03
3 RMTg mRNA stability Pcnx3 0.2 0.13 5.2e-04 0.08 0.09 0.1 0.06 3.2e-03 2.3e-03 1.3e-03 9.3e-03
4 PL gene expression Pcnx3 0.06 0.04 3.4e-05 0.04 0.04 0.04 0.04 7.4e-05 6.4e-05 5.4e-05 9.1e-05
5 Adipose mRNA stability Pcnx3 0.22 0.1 1.2e-03 0 0.02 0.03 0 1.4e-01 2.3e-03 7.4e-04 7.3e-02
6 BLA gene expression Pcnx3 0.11 0.06 5.5e-04 0.06 0.06 0.06 0.06 3.5e-04 2.5e-04 5.2e-04 2.3e-04
7 Adipose gene expression Pcnx3 0.13 0.06 8.2e-10 0.09 0.07 0.08 0.08 5.9e-10 7.7e-08 6.7e-09 1.7e-09
8 NAcc gene expression Pcnx3 0.03 0.02 2.1e-03 0.01 0.02 0.01 0.01 4.6e-02 1.0e-03 1.6e-02 8.7e-03
9 Brain gene expression Pcnx3 0.15 0.09 1.6e-08 0.1 0.09 0.1 0.1 2.8e-09 7.1e-09 8.7e-10 1.0e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.13.56.6-1.0-2.0-1.9-2.1-0.72.6-1.91.9-2.0
Area under the delay curve0.50.61.2-0.4-0.7-0.2-0.5-0.71.0-1.10.9-0.8
BMI with tail5.919.036.0-2.1-5.7-2.1-6.0-0.75.0-5.34.1-4.8
BMI without tail2.85.710.2-1.0-3.1-0.7-3.2-0.62.8-3.12.1-2.9
Body weight1.77.216.60.6-4.01.0-4.12.03.3-3.01.2-2.4
Weight adjusted by age0.60.72.21.1-0.71.1-0.61.50.5-0.1-0.4-0.2
Bone surface2.34.18.40.4-2.9-0.9-2.71.72.9-1.91.5-1.8
Bone volume1.83.05.8-0.3-2.2-1.6-2.10.62.4-1.71.7-1.7
Breakpoint value in progressive ratio session0.90.92.41.4-1.10.8-0.71.60.7-0.7-0.1-0.8
Number of licking bursts0.10.10.30.4-0.4-0.2-0.10.50.3-0.20.1-0.4
Context. condit. distance diff. score0.50.62.3-1.30.6-0.60.2-1.5-0.70.30.5-0.1
Locomotion velocity, session 10.20.21.0-0.10.21.0-0.10.3-0.50.2-0.60.6
Locomotion distance, session 11.51.94.0-0.7-1.7-0.5-1.8-0.32.0-1.61.2-1.4
Locomotion velocity, session 21.61.83.90.2-2.00.6-1.91.11.5-1.70.7-1.4
Locomotion distance, session 21.11.63.9-0.3-1.6-0.2-1.6-0.22.0-1.70.9-1.2
Locomotion velocity, session 31.31.53.3-1.8-1.1-0.7-1.8-1.11.0-1.11.3-0.8
Locomotion distance, session 30.00.00.1-0.4-0.00.0-0.2-0.20.1-0.10.10.2
Stereotopy head waving bouts, day 31.31.64.3-2.1-0.8-0.7-1.7-1.41.1-1.01.3-0.3
Stereotopy head waving duration, day 30.60.72.1-1.4-0.2-0.7-0.8-1.20.5-0.40.9-0.1
Locomotion velocity, session 72.72.94.2-1.8-1.3-1.6-1.7-1.81.5-1.72.1-1.8
Locomotion distance, session 70.81.01.5-1.1-0.9-0.4-1.2-1.11.0-1.21.0-1.0
Stereotopy head waving bouts, day 70.40.51.7-0.5-0.4-1.3-0.3-0.80.4-0.50.9-0.7
Stereotopy head waving duration, day 71.01.22.30.4-1.4-1.1-1.0-0.01.3-1.31.0-1.5
Locomotion velocity, session 80.40.51.50.4-0.31.2-0.61.20.10.1-0.80.3
Locomotion distance, session 80.71.02.5-1.6-0.8-0.5-1.4-0.80.6-0.81.3-0.7
Degree of sensitization distance1.11.12.0-1.2-1.0-0.7-1.4-0.81.2-1.11.1-1.0
Degree of sensitization stereotypy0.40.41.00.4-0.8-0.9-0.40.10.5-0.70.6-1.0
Conditioned locomotion0.50.51.80.7-0.71.3-0.81.00.5-0.1-0.4-0.2
Cocaine response after cond. corrected0.40.51.9-1.30.60.0-0.1-1.4-0.30.20.10.6
Cocaine response after cond. not corrected0.40.41.8-1.40.4-0.1-0.3-1.0-0.20.20.20.5
Cocaine response before conditioning0.20.21.20.7-0.5-0.2-0.11.10.0-0.1-0.0-0.4
Saline control response1.11.43.41.1-1.60.7-1.41.81.4-0.7-0.4-0.8
Bone: connectivity density2.53.98.7-0.1-2.5-1.3-2.40.52.9-2.11.6-2.2
Bone: cortical apparent density0.30.41.81.40.10.60.70.2-0.2-0.5-0.6-0.4
Bone: cortical area0.20.21.00.4-0.50.5-0.61.00.10.1-0.10.1
Bone: cortical porosity0.70.71.4-0.3-0.9-0.7-0.8-0.51.2-0.90.8-1.1
Bone: cortical porosity0.60.71.80.1-1.0-0.3-0.90.01.3-1.00.5-1.0
Bone: cortical thickness1.21.95.72.1-0.22.40.22.0-0.40.4-1.60.3
Bone: cortical thickness0.91.03.41.10.41.80.50.8-0.80.5-1.40.6
Bone: cortical tissue density0.40.52.21.50.10.70.80.4-0.2-0.5-0.7-0.3
Condit. Reinf. active minus inactive responses0.20.20.40.1-0.6-0.3-0.4-0.30.5-0.50.3-0.7
Condit. Reinf. active-inactive response ratio0.10.10.40.60.0-0.10.5-0.3-0.0-0.1-0.1-0.3
Condit. Reinf. active responses0.40.50.7-0.6-0.8-0.5-0.8-0.20.7-0.70.8-0.8
Condit. Reinf. inactive responses0.80.92.1-1.5-0.9-0.7-1.3-0.20.8-0.71.2-0.7
Incentive salience index mean0.70.91.6-0.4-1.2-0.3-1.2-0.31.1-1.00.9-1.2
Condit. Reinf. lever presses0.50.61.9-0.6-1.10.2-1.40.40.6-0.50.8-0.8
Condit. Reinf. active minus inactive responses0.20.31.6-0.3-0.1-1.30.0-0.30.50.00.6-0.1
Condit. Reinf. active-inactive response ratio0.60.62.2-1.3-0.1-1.5-0.4-0.40.4-0.11.20.1
Condit. Reinf. active responses0.40.61.80.2-0.6-1.4-0.2-0.31.2-0.50.7-0.9
Condit. Reinf. inactive responses0.50.61.80.7-0.8-0.6-0.2-0.31.2-0.80.2-1.3
Condit. Reinf. lever presses0.70.92.51.0-1.3-0.6-0.91.61.1-0.50.3-0.8
Condit. Reinf. lever reinforcers received0.40.51.40.6-0.6-1.2-0.10.11.2-0.40.5-0.9
Conditioned reinforcement - actives0.40.41.1-0.10.7-0.10.61.1-0.50.9-0.20.8
Conditioned reinforcement - inactives2.12.45.3-1.02.3-1.22.2-0.8-1.71.8-0.01.4
Conditioned locomotion3.23.88.7-1.33.0-0.52.6-0.2-2.42.4-0.52.2
Patch foraging indifference point 0 sec0.00.00.1-0.10.0-0.30.1-0.10.0-0.00.2-0.1
Patch foraging indifference point AUC1.01.24.61.8-0.90.8-0.32.10.6-0.5-0.5-0.5
Delay disc. indifference point, 0s delay0.70.71.5-1.0-0.6-0.1-0.7-0.90.9-1.21.1-0.7
Delay disc. indifference point, 16s delay0.60.61.6-0.60.0-1.30.3-1.20.2-0.80.9-0.3
Delay disc. indifference point, 2s delay0.20.20.5-0.7-0.3-0.7-0.4-0.50.3-0.30.6-0.0
Delay disc. indifference point, 24s delay0.20.20.90.20.40.90.4-0.3-0.20.0-0.50.3
Delay disc. indifference point, 4s delay0.30.30.5-0.7-0.40.1-0.4-0.60.7-0.70.6-0.6
Delay disc. indifference point, 8s delay0.20.20.6-0.3-0.40.5-0.3-0.40.8-0.60.4-0.4
Indifference point function ln k2.33.210.9-2.81.9-0.91.0-3.3-1.51.00.31.2
Indifference point function log k2.33.210.9-2.81.9-0.91.0-3.3-1.51.00.31.2
Patch foraging total patch changes 0 sec0.00.10.10.10.30.20.40.1-0.30.3-0.30.2
Patch foraging total patch changes 12 sec1.41.93.51.8-1.80.4-1.01.91.3-1.30.0-1.5
Patch foraging total patch changes 18 sec0.40.50.80.3-0.9-0.3-0.70.90.9-0.80.5-0.7
Patch foraging total patch changes 24 sec0.91.15.11.6-0.51.0-0.22.30.40.1-0.9-0.1
Patch foraging total patch changes 6 sec0.40.61.20.3-1.1-0.3-0.90.91.0-0.80.2-0.9
Patch foraging time to switch 0 sec2.74.17.4-0.4-2.7-1.2-2.50.12.4-2.32.0-2.6
Patch foraging water rate 0 sec3.35.310.5-0.43.20.62.8-0.8-2.92.9-1.72.9
Patch foraging water rate 12 sec4.87.415.8-1.14.00.53.1-1.9-3.13.2-2.03.4
Patch foraging water rate 18 sec1.21.63.1-1.41.80.11.0-1.2-1.31.5-0.61.7
Patch foraging water rate 24 sec2.43.36.4-1.12.50.61.7-1.3-2.32.1-1.12.4
Patch foraging water rate 6 sec2.43.67.0-1.12.60.71.8-1.4-2.02.4-1.52.5
Seeking ratio, delayed vs. immediate footshock0.60.72.0-0.1-0.6-1.0-0.3-1.40.6-0.90.7-1.0
Distance traveled before self-admin0.20.20.60.6-0.60.3-0.30.80.4-0.30.2-0.4
Distance traveled after self-admin0.10.10.50.7-0.10.00.30.30.0-0.0-0.1-0.3
Extensor digitorum longus weight2.28.818.72.4-4.32.4-3.83.52.6-2.80.3-2.8
Bone: elastic displacement1.71.93.40.01.81.01.5-0.3-1.41.8-1.61.8
Bone: elastic work0.60.73.00.80.11.70.10.9-0.10.5-1.30.7
Bone: endosteal estimation1.63.69.2-3.0-1.1-2.1-2.2-1.71.5-1.22.4-0.6
Bone: endosteal perimeter1.73.68.4-2.9-0.9-2.8-1.9-1.51.4-0.82.5-0.7
Epididymis fat weight0.71.76.4-2.50.8-1.80.1-1.8-0.10.31.30.4
Delta time in closed arm before/after self-admin0.30.21.3-0.5-0.11.2-0.50.30.3-0.1-0.40.2
Delta time in open arm before/after self-admin0.30.30.91.00.4-0.10.80.5-0.70.5-0.30.1
Diff in mean of infusions in LGA sessions0.60.72.21.00.21.30.41.5-0.30.4-0.80.5
Delay discount exponential model param0.40.40.90.30.60.10.40.6-0.80.9-0.70.7
Extinction: sum of active levers before priming2.22.24.31.2-2.10.5-1.60.81.6-1.80.7-2.0
Active lever presses in extinction session 61.61.56.51.4-0.11.8-0.12.6-0.40.6-1.00.8
Bone: final force1.01.63.50.6-1.90.8-1.91.71.3-1.00.4-1.0
Bone: final moment0.91.43.20.5-1.80.7-1.81.61.2-1.00.4-0.9
Food consumed during 24 hour testing period0.91.12.21.10.90.51.21.1-0.91.5-0.91.0
Glucose1.52.25.6-2.4-0.4-2.0-1.0-1.90.9-0.91.9-0.6
Heart weight0.81.13.8-2.00.9-1.10.4-1.8-0.40.30.70.4
Delay discount hyperbolic model param0.30.30.70.30.60.10.40.5-0.80.9-0.70.6
Intermittent access intake day 1-15 change1.41.42.30.21.50.61.41.0-1.31.5-0.81.4
Intermittent access intake escalation0.70.71.30.01.10.11.10.6-0.91.0-0.40.9
Intermittent access intake escalation 21.21.21.70.71.30.91.30.8-1.31.2-0.91.1
Intermitt. access day 1 inactive lever presses0.50.51.1-0.91.0-0.31.1-0.6-0.70.60.40.5
Intermitt. access day 15 inactive lever presses0.80.81.6-1.01.3-0.91.2-0.2-0.81.00.31.0
Intermitt. access escalation Index2.22.07.7-1.80.1-2.3-0.0-2.80.4-0.41.1-0.4
Intermittent access day 1 total infusions3.94.513.9-3.6-0.3-3.7-0.8-1.81.1-0.72.7-0.7
Intermittent access day 15 total infusions2.32.58.2-2.91.4-2.70.9-0.8-0.61.01.30.9
Intermittent access terminal intake (last 3 days)2.12.38.1-2.80.8-2.80.3-0.8-0.10.61.60.6
Intermittent access total infusions2.73.011.5-3.00.2-3.4-0.2-1.20.6-0.12.1-0.2
Intermittent access day 1 locomotion3.43.511.3-3.4-0.7-2.8-1.1-1.31.3-1.02.4-0.8
Intermittent access day 15 total locomotion1.11.24.4-2.11.0-1.70.7-0.2-0.30.61.10.5
Intermittent access total locomotion3.33.712.7-3.60.0-3.4-0.5-1.20.7-0.42.6-0.4
Intermittent access standard deviation0.80.81.7-0.41.30.31.20.8-0.91.2-0.31.1
Left kidney weight0.20.51.0-0.90.8-0.30.5-1.0-1.00.60.40.5
Right kidney weight0.30.82.3-0.10.90.50.80.6-1.51.0-0.31.2
Cocaine induced anxiety0.10.10.2-0.10.20.00.00.5-0.40.3-0.10.4
Post-drug Anxiety0.70.83.60.8-0.11.3-0.41.9-0.50.4-0.70.7
Baseline Anxiety1.31.44.81.2-0.62.2-0.62.10.1-0.2-0.80.1
Tail length1.13.59.12.20.93.01.12.1-1.11.4-2.41.4
Length with tail0.93.29.82.4-0.52.9-0.33.10.10.5-1.90.9
Length without tail0.61.45.41.2-1.11.2-1.12.30.9-0.2-0.70.3
Times rat made contact with spout0.30.30.90.8-0.50.2-0.10.00.7-0.7-0.1-0.9
Lifetime Intake2.73.010.5-3.0-0.1-3.2-0.5-1.20.9-0.42.1-0.4
Liver weight, left0.10.10.3-0.6-0.0-0.1-0.4-0.3-0.5-0.20.20.1
Liver weight, right0.20.31.3-1.2-0.10.1-0.9-0.1-0.20.00.10.5
Locomotor activity1.32.14.0-0.72.01.01.5-0.3-1.61.7-1.32.0
Locomotor testing distance1.62.75.5-0.82.31.01.7-0.6-1.71.8-1.62.3
Locomotor testing rearing0.81.33.0-0.71.70.21.3-0.9-0.71.4-0.91.4
Locomotion in novel chamber1.41.73.4-1.81.6-1.41.2-0.6-1.41.40.51.3
Locomotion in novel chamber post-restriction0.91.12.2-1.41.2-1.51.0-1.0-1.20.80.30.7
Fecal boli incidents, locomotor time 10.10.10.60.2-0.0-0.2-0.00.8-0.20.20.40.2
Change in fecal boli incidents, locomotor task0.50.51.1-1.0-0.70.3-1.1-0.10.8-0.80.4-0.5
Time >=10cm from walls, locomotor time 12.12.14.9-2.2-1.0-1.8-1.40.11.1-0.92.2-0.8
Bouts of movement, locomotor time 11.11.27.02.6-0.01.30.90.7-0.1-0.1-0.9-0.4
Total resting periods, locomotor time 10.70.84.92.2-0.10.80.70.6-0.0-0.2-0.5-0.5
Rest time, locomotor task time 10.80.91.9-0.51.20.50.90.3-1.21.2-0.41.4
Distance moved, locomotor task time 11.11.22.0-0.6-1.1-1.4-1.1-0.71.2-1.21.0-1.1
Vertical activity count, locomotor time 10.40.51.2-0.90.7-0.80.5-1.1-0.50.40.10.4
Time >=10cm from walls, locomotor time 20.10.10.20.3-0.20.00.10.30.1-0.10.4-0.5
Bouts of movement, locomotor time 20.30.32.11.4-0.20.20.4-0.00.2-0.5-0.3-0.5
Total resting periods, locomotor time 20.20.21.21.1-0.3-0.00.3-0.10.3-0.60.0-0.5
Rest time, locomotor task time 20.50.52.6-1.60.7-0.10.3-0.4-0.50.40.60.8
Distance moved, locomotor task time 20.20.31.61.3-0.40.3-0.10.40.2-0.1-0.6-0.4
Vertical activity count, locomotor time 21.21.32.60.51.21.11.00.3-1.31.3-1.61.2
Light reinforcement 10.20.41.10.40.90.11.10.1-0.60.7-0.70.6
Light reinforcement 20.50.61.3-0.51.0-0.70.7-0.0-1.11.10.11.0
Bone: marrow area1.73.89.6-3.1-1.2-2.1-2.2-1.81.5-1.32.4-0.7
Bone: maximum diameter0.10.31.2-0.3-0.30.0-0.71.10.10.40.20.6
Bone: maximum force2.44.18.7-0.1-2.9-0.4-2.91.32.6-2.11.6-2.0
Bone: maximum moment2.13.67.9-0.2-2.8-0.4-2.81.22.4-2.01.5-1.9
Mean time between licks in bursts0.30.41.70.3-0.21.3-0.40.70.4-0.2-0.90.1
Mean num. licks in bursts0.10.10.50.00.3-0.10.3-0.70.1-0.1-0.1-0.2
Cd content in liver1.21.32.6-0.11.6-0.31.60.2-1.31.6-0.51.5
Co content in liver2.12.55.60.82.21.12.4-0.3-1.71.6-1.71.4
Cu content in liver0.30.41.30.6-0.7-0.2-0.2-0.20.5-0.90.4-1.1
Fe content in liver0.10.20.8-0.1-0.10.3-0.40.9-0.10.3-0.20.4
K content in liver2.42.45.2-0.6-2.1-0.6-2.30.11.8-1.81.4-1.7
Mg content in liver3.23.34.5-1.0-1.9-1.9-1.8-1.32.0-2.11.9-2.1
Mn content in liver0.70.83.11.0-1.10.0-0.81.81.0-0.40.0-0.7
Na content in liver0.40.52.00.6-0.31.1-0.41.4-0.30.2-0.40.2
Rb content in liver1.11.34.2-1.3-0.1-1.8-0.0-2.10.8-0.61.1-0.8
Se content in liver0.40.52.9-0.1-0.3-1.7-0.10.20.90.10.7-0.3
Sr content in liver1.91.84.82.10.11.70.62.2-0.80.6-1.40.6
Zn content in liver0.50.61.10.8-1.00.3-0.60.40.8-1.00.3-1.0
Bone: minimum diameter2.34.46.7-2.5-1.4-2.6-1.9-2.31.8-1.82.6-1.7
Time in familiar zone, hab. session 10.50.51.3-0.9-0.3-1.1-0.5-0.80.1-0.40.8-0.6
Time in novel zone, hab. session 10.80.81.80.31.01.30.80.4-0.50.8-1.01.2
Total zone transitions, hab. session 10.30.51.30.6-0.9-0.1-0.50.30.7-0.80.3-1.2
Total locomotion distance, hab. session 10.40.61.4-1.2-0.5-0.2-0.9-0.80.4-0.71.1-0.6
Locomotion velocity, hab. session 10.40.50.9-0.7-0.7-0.2-0.9-0.70.6-0.80.9-0.7
Time in familiar zone, hab. session 20.30.30.7-0.30.50.80.10.1-0.30.5-0.90.9
Time in novel zone, hab. session 20.50.51.20.3-0.7-0.7-0.2-0.30.7-1.00.8-1.1
Total zone transitions, hab. session 23.44.49.7-0.4-2.6-1.2-2.4-0.43.1-2.51.8-2.5
Total locomotion distance, hab. session 22.12.84.1-1.5-1.7-1.0-2.0-1.22.0-1.91.8-1.5
Locomotion velocity, hab. session 22.12.84.2-1.7-1.6-1.2-2.0-1.31.9-1.72.0-1.4
Novel to familiar place preference ratio0.50.50.90.9-0.9-0.5-0.40.80.5-0.70.5-1.0
Novelty place preference0.30.30.70.7-0.6-0.7-0.10.50.3-0.60.5-0.8
Time in novel zone, NPP test0.20.30.50.6-0.6-0.6-0.10.40.3-0.50.5-0.7
Total zone transitions, NPP test1.42.04.10.5-2.00.3-1.70.91.8-1.60.8-1.8
Total locomotion distance, NPP test0.81.11.9-0.8-1.20.0-1.4-0.51.2-1.31.1-1.2
Locomotion velocity, NPP test0.71.01.6-0.5-1.20.0-1.2-0.51.1-1.31.1-1.3
Intraocular pressure1.52.13.90.41.80.71.81.2-1.82.0-0.91.6
Delta distance traveled before/after self-admin0.10.10.2-0.00.40.10.4-0.2-0.30.3-0.40.3
Delta ambulatory time before/after self-admin0.10.10.30.10.30.40.4-0.1-0.20.3-0.60.3
Parametrial fat weight1.52.97.7-2.8-0.4-2.1-0.9-2.50.5-0.92.3-0.8
Pavlov. Cond. lever latency0.30.41.00.31.00.11.0-0.1-0.60.6-0.70.6
Pavlov. Cond. magazine entry latency0.91.21.9-0.1-1.3-0.9-0.9-0.81.2-1.31.3-1.4
Pavlov. Cond. change in total contacts0.40.40.80.2-0.7-0.7-0.2-0.40.2-0.70.9-0.9
Pavlov. Cond. index score0.10.10.20.3-0.5-0.0-0.20.00.1-0.20.4-0.4
Pavlov. Cond. latency score0.10.20.4-0.1-0.6-0.1-0.5-0.20.3-0.40.6-0.5
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.50.1-0.6-0.30.2-0.20.5-0.3
Pavlov. Cond. magazine entry number0.10.21.0-1.00.1-0.1-0.4-0.40.3-0.10.10.1
Pavlov. Cond. intertrial magazine entries0.60.71.80.21.1-0.71.3-0.1-1.01.0-0.50.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.4-0.70.0-0.40.00.3-0.50.5-0.6
Pavlov. Cond. response bias0.00.10.30.6-0.20.00.20.0-0.30.10.1-0.1
Pavlov. Cond. lever latency0.20.30.8-0.20.70.20.8-0.9-0.50.2-0.40.4
Pavlov. Cond. magazine entry latency1.41.73.21.2-1.8-0.0-1.20.91.6-1.70.5-1.6
Pavlov. Cond. change in total contacts0.91.22.01.2-1.4-1.0-0.81.01.2-1.20.8-1.3
Pavlov. Cond. index score1.01.22.50.9-1.6-0.3-1.21.11.2-1.20.6-1.3
Pavlov. Cond. latency score0.91.12.30.6-1.5-0.3-1.31.01.1-1.20.7-1.2
Pavlov. Cond. lever contacts0.20.31.90.7-0.10.2-0.11.4-0.10.4-0.30.3
Pavlov. Cond. magazine entry number2.12.54.6-2.02.10.01.3-1.6-1.81.8-0.31.8
Pavlov. Cond. intertrial magazine entries0.30.41.0-1.00.8-0.20.4-0.5-0.80.80.10.8
Pavlov. Cond. lever-magazine prob. diff.1.11.42.81.1-1.7-0.2-1.21.21.3-1.30.6-1.4
Pavlov. Cond. response bias0.50.62.21.2-1.00.0-0.61.50.7-0.40.1-0.5
Time in closed arm before self-admin0.10.10.4-0.0-0.3-0.6-0.30.10.2-0.20.5-0.2
Time in closed arm after self-admin0.20.20.7-0.8-0.4-0.1-0.6-0.10.4-0.40.3-0.2
Time in open arm before self-admin0.30.31.9-0.30.40.30.3-1.40.0-0.1-0.40.1
Time in open arm after self-admin0.70.81.70.91.10.51.3-0.4-1.00.9-1.00.7
Bone: periosteal estimation0.61.12.9-1.6-1.0-0.9-1.7-0.30.8-0.61.4-0.2
Bone: periosteal perimeter0.40.71.7-0.8-0.9-0.9-1.30.21.1-0.41.0-0.4
Bone: post-yield work8.711.817.8-2.2-3.7-3.6-3.8-1.43.7-3.74.2-3.7
Progressive ratio test 1 active lever presses1.01.13.5-1.31.1-1.90.9-1.1-0.40.80.50.6
Progressive ratio test 1 breakpoint1.01.13.1-1.11.2-1.81.0-1.1-0.60.90.30.7
Progressive ratio test 1 inactive lever presses0.40.41.1-0.70.6-1.00.7-1.0-0.10.20.40.0
Progressive ratio test 2 active lever presses1.51.65.6-1.81.2-2.41.0-0.7-0.40.90.80.7
Progressive ratio test 2 breakpoint1.82.04.3-1.71.8-2.11.6-0.9-1.01.40.31.2
Progressive ratio test 2 inactive lever presses2.42.78.7-2.41.6-3.01.5-1.4-0.71.01.30.7
Incentive Sensitization - Responses0.30.31.5-0.70.2-1.20.20.00.20.10.60.0
Incentive Sensitization - Breakpoint0.30.31.4-0.80.4-1.20.30.00.10.30.50.2
Sum of active levers in priming session hrs 5-62.52.47.41.70.71.60.92.7-1.31.4-1.41.2
Progressive ratio3.64.17.6-0.4-2.8-0.6-2.70.32.6-2.52.0-2.2
Food seeking constrained by brief footshock0.10.10.30.1-0.10.4-0.10.30.1-0.0-0.50.1
Seeking ratio, punishment vs. effort2.32.85.50.02.30.52.2-0.7-2.02.0-1.81.8
Retroperitoneal fat weight1.75.715.2-3.91.7-3.50.7-3.9-0.70.71.80.8
Reaction time number correct0.50.72.00.60.31.40.11.2-0.40.6-0.90.9
Reaction time mean minus median0.81.12.71.3-1.50.3-1.01.60.7-0.90.3-0.9
Reaction time mean minus median AUC0.40.52.31.2-0.60.7-0.31.5-0.1-0.2-0.3-0.0
Reaction time num false alarms0.20.30.7-0.60.50.80.2-0.6-0.60.3-0.60.6
Reaction time num false alarms AUC0.20.21.3-0.10.11.2-0.1-0.1-0.4-0.1-0.60.3
Reaction time trials correct on left0.50.72.00.60.31.40.11.2-0.40.6-0.90.9
Reaction time trials on left0.60.82.40.70.31.60.11.3-0.40.7-1.00.9
Reaction time mean0.10.10.50.70.0-0.30.40.2-0.6-0.10.10.0
Reaction time mean AUC0.10.10.40.6-0.1-0.40.30.1-0.5-0.30.3-0.2
Median of all reaction times0.10.10.40.40.2-0.50.5-0.3-0.6-0.10.30.0
Reaction time omissions0.40.61.61.3-0.71.1-0.31.00.1-0.6-0.2-0.4
Reaction time false alarm rate0.10.20.6-0.70.20.3-0.1-0.8-0.4-0.2-0.20.1
Reaction time premature initiation rate0.60.82.81.4-0.61.7-0.50.60.2-0.3-1.30.0
Reaction time premature initiations1.42.06.92.2-0.42.6-0.21.6-0.10.1-1.90.4
Std. dev. reaction times0.20.31.31.1-0.50.1-0.10.9-0.1-0.40.0-0.3
Reaction time trials completed0.60.82.40.70.31.60.11.3-0.40.7-1.00.9
Reaction time trials AUC0.40.51.70.50.31.30.11.0-0.30.6-0.90.8
Run reversals in cocaine runway, females2.72.64.4-1.2-2.0-0.6-2.1-0.51.8-2.11.5-1.8
Run reversals in cocaine runway, males2.01.93.20.21.61.11.30.6-1.81.8-1.51.8
Latency to leave start box in cocaine runway1.11.21.7-1.0-1.0-1.3-1.1-0.91.0-1.11.3-1.1
Latency to leave start box in cocaine runway, F0.60.61.30.0-0.7-1.0-0.4-1.10.6-0.90.8-1.1
Latency to leave start box in cocaine runway, M0.40.41.5-1.2-0.5-0.3-1.00.40.4-0.30.50.1
Std. dev. time between licks in bursts0.30.41.5-0.30.51.20.10.0-0.60.2-0.90.6
Total sessions with >9 infusions1.41.66.3-2.5-0.3-1.8-0.8-0.90.7-0.51.5-0.4
Short access day 1 total inactive lever presses0.91.03.5-1.90.8-1.30.6-1.2-0.30.30.90.3
Short access day 10 total inactive lever presses0.80.91.9-1.21.4-0.21.3-1.1-1.00.8-0.00.9
Short access day 1 total infusions2.93.18.2-2.6-0.5-2.9-0.8-2.01.1-0.92.1-1.0
Short access day 10 total infusions4.95.413.3-3.1-1.5-3.6-1.8-1.42.2-1.72.9-1.5
Short access total infusions2.52.86.8-2.6-0.9-2.6-1.2-1.11.4-1.02.0-0.9
Short access day 1 locomotion2.12.26.8-2.6-0.4-2.5-0.7-1.01.1-0.71.8-0.7
Short access day 10 total locomotion1.92.25.0-2.2-0.6-2.2-0.8-1.41.3-0.91.8-0.8
Short access total locomotion1.92.04.9-2.2-0.7-2.0-0.9-1.01.3-0.91.8-0.9
One hour access (0.3 mA shock)2.93.47.4-2.72.2-2.51.7-1.3-1.31.70.71.6
Compulsive drug intake1.01.04.82.2-0.21.40.2-0.20.1-0.1-1.5-0.1
One hour access (shock baseline)2.52.97.1-2.71.9-2.41.5-0.7-1.21.51.11.3
Social response proportion0.30.41.30.7-0.70.0-0.51.20.7-0.50.0-0.3
Social responses0.20.30.80.60.20.60.20.9-0.10.5-0.70.4
Social time0.30.41.00.80.11.00.10.9-0.00.5-0.80.6
Soleus weight1.02.97.7-2.62.0-1.11.2-2.8-1.51.30.61.3
Bone: stiffness2.03.26.60.2-2.6-0.7-2.30.92.1-2.01.5-2.0
Tibialis anterior weight2.79.131.93.7-3.14.0-2.65.61.0-0.9-1.6-0.7
Time to tail flick, vehicle, before self-admin0.70.81.6-0.3-1.1-0.3-1.30.61.1-0.90.8-0.8
Time to tail flick, vehicle, after self-admin1.61.74.2-0.5-1.80.2-2.00.01.6-1.60.9-1.3
Time to tail flick, test, before self-admin2.01.94.0-2.0-0.9-1.4-1.4-1.31.4-1.21.6-1.0
Time to tail flick, test, after self-admin0.10.10.20.30.20.50.20.5-0.20.3-0.40.3
Delta time to tail flick, vehicle, before/after SA0.40.40.9-0.1-0.90.2-0.9-0.20.9-0.90.3-0.6
Delta time to tail flick, test, before/after SA3.63.26.52.51.22.01.61.7-1.71.6-2.11.3
Tibia length0.51.37.81.3-0.40.8-0.22.8-0.20.7-0.50.7
Ambulatory time before self-admin0.10.10.70.4-0.4-0.2-0.20.80.2-0.10.3-0.2
Ambulatory time after self-admin0.20.31.0-0.2-0.3-1.00.1-0.30.3-0.40.7-0.7
Bone: tissue strength0.10.10.40.1-0.2-0.6-0.20.30.6-0.10.3-0.4
Total heroin consumption1.61.94.02.0-1.71.4-1.21.51.2-1.2-0.3-1.1
Bone: trabecular number1.52.34.8-0.5-1.7-2.0-1.5-0.22.2-1.41.6-1.5
Bone: trabecular spacing0.20.30.80.00.60.90.6-0.3-0.90.1-0.60.4
Bone: trabecular thickness0.91.13.3-1.0-0.4-1.8-0.3-1.31.1-0.51.2-0.9
Bone: trabecular tissue density1.01.53.6-1.01.9-0.21.5-1.2-1.31.3-0.21.2
Water consumed over 24 hours0.50.62.81.70.00.60.70.80.10.3-0.8-0.1
Number of responses in last shaping day0.60.61.4-0.41.2-0.41.1-0.4-0.80.9-0.50.8