Hub : Genes

Pclo

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Pclo 0.07 0.04 1.5e-04 0.07 0.06 0.06 0.04 1.4e-04 3.7e-04 4.3e-04 1.9e-03
2 PL alternative polyA XM_039108295.1 0.21 0.1 3.0e-07 0.03 0.06 0.06 0.06 1.0e-04 2.9e-07 9.0e-07 6.5e-07
3 PL alternative polyA NM_001110797.2 0.2 0.09 5.8e-07 0.04 0.06 0.05 0.06 7.8e-05 5.3e-07 2.6e-06 7.6e-07
4 Liver gene expression Pclo 0.03 0.02 1.5e-04 0.03 0.02 0.02 0.02 6.7e-04 3.2e-03 3.2e-03 5.5e-03
5 OFC alternative polyA XM_039108295.1 0.12 0.09 7.7e-03 0.01 0.09 0.04 0.03 1.9e-01 3.8e-03 3.6e-02 5.5e-02
6 Brain gene expression Pclo 0.04 0.03 3.5e-04 0.04 0.03 0.02 0.02 3.0e-04 1.4e-03 2.6e-03 3.1e-03
7 LHb mRNA stability Pclo 0.37 0.19 2.3e-03 0.12 0.08 0.08 0.1 1.0e-03 6.7e-03 6.8e-03 2.7e-03
8 Brain alternative polyA NM_001110797.2 0.05 0.04 3.3e-03 0.03 0.03 0.03 0.03 8.3e-04 1.2e-03 1.0e-03 1.2e-03
9 Brain alternative polyA XM_039108295.1 0.05 0.04 3.0e-03 0.03 0.03 0.03 0.03 6.6e-04 1.1e-03 9.8e-04 1.2e-03
10 OFC isoform ratio NM_001110797.2 0.26 0.21 7.1e-03 0.05 0.08 0.06 0.06 2.5e-02 7.0e-03 1.6e-02 1.4e-02
11 PL isoform ratio NM_020098.2 0.03 0.03 9.0e-03 0.02 0.02 0.02 0.01 5.3e-03 3.6e-03 1.4e-03 1.2e-02
12 Brain isoform ratio NM_001110797.2 0.09 0.06 5.6e-04 0.04 0.04 0.04 0.04 6.7e-05 8.3e-05 1.8e-04 1.1e-04
13 Brain isoform ratio NM_020098.2 0.06 0.04 2.3e-04 0.04 0.03 0.03 0.03 1.6e-04 6.9e-04 1.0e-03 1.5e-03
14 BLA mRNA stability Pclo 0.08 0.06 1.1e-03 0.04 0.05 0.03 0.03 3.4e-03 1.3e-03 1.2e-02 9.1e-03
15 Adipose gene expression Pclo 0.17 0.09 0.0e+00 0.14 0.15 0.16 0.16 7.3e-16 2.2e-16 1.5e-17 5.4e-17
16 PL isoform ratio NM_001110797.2 0.18 0.09 1.7e-06 0.06 0.05 0.05 0.05 2.1e-07 2.8e-06 5.1e-06 2.2e-06
17 IL gene expression Pclo 0.26 0.16 3.1e-03 0.06 0.08 0.07 0.05 1.3e-02 7.1e-03 9.9e-03 2.7e-02
18 Brain mRNA stability Pclo 0.37 0.13 0.0e+00 0.25 0.26 0.27 0.26 3.1e-23 8.8e-24 7.9e-25 2.4e-24
19 NAcc alternative polyA NM_001110797.2 0.04 0.03 1.6e-03 0.03 0.02 0.02 0.02 2.1e-04 4.7e-03 2.9e-03 5.6e-03
20 NAcc alternative polyA XM_039108295.1 0.04 0.03 4.7e-04 0.03 0.03 0.02 0.02 8.7e-05 6.7e-04 9.1e-04 9.0e-04
21 NAcc gene expression Pclo 0.05 0.03 6.7e-04 0.01 0.02 0.02 0.02 9.8e-03 1.1e-03 1.2e-03 1.4e-03
22 PL mRNA stability Pclo 0.1 0.07 3.7e-05 0.02 0.04 0.04 0.03 3.5e-03 1.0e-05 5.0e-05 2.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.50.81.7-0.60.6-0.7-0.80.8-0.8-1.30.9-0.9-1.0-0.90.8-0.81.1-1.20.91.1-0.80.9-0.9-1.11.1
Area under the delay curve0.30.31.2-0.00.9-0.9-0.00.10.1-0.80.8-0.8-0.2-0.60.2-0.20.3-0.01.1-0.4-0.90.4-0.4-0.30.2
BMI with tail0.10.30.9-0.4-0.60.7-0.40.3-0.60.5-0.90.90.10.0-0.60.6-0.20.1-0.60.61.0-0.20.20.5-0.4
BMI without tail1.32.67.9-0.5-1.61.7-0.60.1-0.72.1-2.52.50.90.6-1.81.8-1.31.2-2.10.12.8-1.51.52.0-1.9
Body weight0.10.41.6-0.60.2-0.1-0.71.0-1.3-0.1-0.30.3-0.8-0.60.3-0.30.7-0.60.51.20.10.3-0.3-0.30.5
Weight adjusted by age0.20.20.70.4-0.00.00.4-0.20.10.5-0.30.30.3-0.2-0.20.2-0.60.8-0.3-0.80.4-0.50.50.7-0.6
Bone surface0.10.20.80.7-0.40.30.7-0.50.4-0.6-0.00.00.10.80.0-0.00.3-0.60.00.3-0.70.2-0.2-0.90.8
Bone volume0.40.62.00.20.2-0.30.30.1-0.0-1.40.9-0.9-0.6-0.40.7-0.70.8-1.10.80.7-1.10.7-0.7-1.31.4
Breakpoint value in progressive ratio session0.50.51.2-0.0-0.50.5-0.30.1-0.50.4-0.40.40.4-0.2-1.11.1-0.71.1-0.8-0.41.1-0.90.91.1-0.9
Number of licking bursts0.91.02.1-0.51.2-1.2-0.50.9-0.8-1.21.5-1.5-1.1-1.41.1-1.11.0-0.71.20.6-0.90.7-0.7-0.70.9
Context. condit. distance diff. score0.70.82.6-1.40.2-0.1-1.40.9-1.31.0-0.80.80.00.2-1.01.0-0.40.7-0.80.21.3-0.50.51.4-1.6
Locomotion velocity, session 10.60.61.9-0.31.2-1.3-0.00.4-0.0-1.41.2-1.2-0.7-0.71.1-1.10.6-0.30.9-0.4-0.80.2-0.2-0.50.6
Locomotion distance, session 12.12.75.2-0.22.1-2.2-0.00.6-0.1-2.32.1-2.1-1.4-0.92.0-2.01.6-1.61.90.2-2.31.5-1.5-1.81.6
Locomotion velocity, session 20.60.72.30.7-0.40.41.0-0.80.80.1-0.60.60.80.1-0.60.6-1.11.3-0.8-1.50.7-0.90.90.9-0.8
Locomotion distance, session 20.20.31.10.80.3-0.41.0-0.70.9-0.60.3-0.30.20.20.0-0.0-0.10.00.1-1.0-0.7-0.30.3-0.40.3
Locomotion velocity, session 31.82.15.3-1.82.3-2.3-1.42.0-2.0-1.71.4-1.4-1.7-1.31.2-1.21.3-0.91.50.9-1.00.5-0.5-0.20.3
Locomotion distance, session 30.50.52.4-1.51.1-1.0-1.21.2-1.5-0.40.3-0.3-0.7-0.40.0-0.00.30.00.10.50.1-0.20.20.6-0.7
Stereotopy head waving bouts, day 30.40.51.5-0.61.0-1.0-0.60.8-0.5-1.20.6-0.6-0.8-0.70.6-0.60.7-0.60.90.4-0.70.5-0.5-0.40.4
Stereotopy head waving duration, day 30.60.82.60.31.0-1.10.20.20.2-1.61.0-1.0-0.6-0.81.1-1.10.6-0.61.3-0.2-1.20.6-0.6-0.80.8
Locomotion velocity, session 70.20.20.70.00.7-0.70.00.4-0.4-0.50.9-0.9-0.30.00.2-0.20.2-0.00.3-0.1-0.4-0.40.40.1-0.1
Locomotion distance, session 70.60.83.0-1.51.2-1.1-1.41.7-1.70.10.4-0.4-1.0-0.20.3-0.30.8-0.60.41.2-0.1-0.00.00.3-0.4
Stereotopy head waving bouts, day 72.62.95.0-1.51.1-1.1-1.61.8-1.7-1.81.6-1.6-1.9-2.11.5-1.51.9-1.91.42.2-1.11.9-1.9-1.61.8
Stereotopy head waving duration, day 72.63.26.9-1.21.2-1.3-1.21.4-1.3-2.21.9-1.9-1.8-2.61.9-1.91.8-1.71.71.6-1.42.2-2.2-1.82.1
Locomotion velocity, session 80.81.02.2-0.91.3-1.3-0.80.9-0.7-1.21.2-1.2-1.1-1.50.9-0.90.9-0.71.20.4-1.00.9-0.9-0.80.8
Locomotion distance, session 80.71.13.8-0.90.3-0.2-0.60.4-0.71.0-1.01.00.40.6-1.31.3-0.91.1-1.1-0.81.3-1.11.11.7-1.9
Degree of sensitization distance0.20.20.80.5-0.60.70.3-0.30.40.9-0.60.60.30.8-0.30.3-0.1-0.2-0.30.30.2-0.20.2-0.0-0.0
Degree of sensitization stereotypy1.61.74.6-1.30.5-0.5-1.31.3-1.5-1.21.1-1.1-1.5-2.11.0-1.01.4-1.40.81.8-0.61.7-1.7-1.31.5
Conditioned locomotion0.50.61.20.8-0.90.90.7-0.91.00.1-0.30.30.90.8-0.90.9-0.90.8-0.7-0.90.5-1.11.10.6-0.6
Cocaine response after cond. corrected0.50.61.5-1.11.1-1.1-1.11.2-1.1-0.70.6-0.6-0.9-1.10.4-0.40.4-0.20.60.4-0.00.5-0.50.3-0.2
Cocaine response after cond. not corrected0.10.10.3-0.30.5-0.5-0.30.4-0.3-0.20.2-0.2-0.3-0.10.1-0.10.2-0.20.20.1-0.10.3-0.30.0-0.1
Cocaine response before conditioning0.50.62.61.1-1.01.00.9-1.11.10.9-0.80.80.71.6-0.50.5-0.2-0.4-0.6-0.1-0.1-0.20.2-0.60.4
Saline control response0.10.10.3-0.1-0.30.3-0.0-0.20.20.1-0.00.00.10.30.2-0.20.2-0.6-0.00.3-0.00.5-0.5-0.50.4
Bone: connectivity density0.40.61.1-0.70.8-0.8-1.00.9-0.9-0.80.5-0.5-0.9-0.10.7-0.70.9-1.10.61.0-0.70.7-0.7-0.70.6
Bone: cortical apparent density0.50.72.80.4-0.40.30.3-0.20.5-0.20.5-0.5-0.50.20.7-0.70.9-1.50.71.1-0.90.9-0.9-1.61.7
Bone: cortical area0.91.44.42.1-1.81.71.9-1.71.50.3-1.01.01.31.6-0.90.9-0.80.3-1.0-0.60.3-0.90.9-0.20.2
Bone: cortical porosity0.60.62.71.7-0.50.51.5-1.31.5-0.1-0.30.31.01.0-0.20.2-0.60.7-0.1-1.1-0.2-0.30.3-0.0-0.1
Bone: cortical porosity2.52.76.32.5-1.71.72.4-2.32.31.0-1.31.32.12.0-1.21.2-1.71.6-1.2-1.90.8-1.31.30.8-0.9
Bone: cortical thickness0.30.41.60.8-1.31.20.5-0.50.30.2-0.80.80.50.8-0.60.6-0.3-0.2-0.80.40.6-0.50.5-0.10.2
Bone: cortical thickness0.30.41.4-0.00.1-0.1-0.10.10.0-1.20.4-0.4-0.4-0.30.7-0.70.6-0.90.70.6-0.60.7-0.7-0.90.9
Bone: cortical tissue density0.50.72.50.2-0.30.30.2-0.10.4-0.10.5-0.5-0.50.10.7-0.70.9-1.40.71.1-0.90.9-0.9-1.61.6
Condit. Reinf. active minus inactive responses0.10.10.6-0.40.3-0.3-0.40.3-0.2-0.40.2-0.2-0.4-0.80.0-0.00.1-0.00.1-0.0-0.10.1-0.1-0.10.1
Condit. Reinf. active-inactive response ratio0.00.00.1-0.10.1-0.1-0.20.00.1-0.2-0.20.20.00.2-0.30.3-0.20.1-0.2-0.40.2-0.30.30.3-0.3
Condit. Reinf. active responses0.30.41.1-0.40.6-0.6-0.30.4-0.1-0.60.6-0.6-0.7-1.00.7-0.70.7-0.60.70.3-0.70.7-0.7-0.80.9
Condit. Reinf. inactive responses0.50.61.90.20.3-0.30.4-0.00.3-0.50.9-0.9-0.6-1.01.0-1.00.7-0.70.90.4-1.10.9-0.9-1.31.4
Incentive salience index mean0.10.10.3-0.30.3-0.4-0.20.2-0.1-0.50.4-0.4-0.4-0.60.1-0.10.2-0.10.3-0.0-0.40.2-0.2-0.30.3
Condit. Reinf. lever presses0.60.92.4-0.10.7-0.7-0.00.30.0-1.11.1-1.1-0.8-0.50.9-0.91.0-1.01.10.7-1.50.9-0.9-1.41.4
Condit. Reinf. active minus inactive responses0.40.51.1-0.41.1-1.1-0.50.7-0.7-1.10.7-0.7-0.8-0.00.7-0.70.9-0.90.70.6-0.90.4-0.4-0.70.5
Condit. Reinf. active-inactive response ratio0.20.20.50.30.5-0.50.10.1-0.0-0.70.4-0.4-0.30.20.4-0.40.5-0.60.40.2-0.70.2-0.2-0.60.5
Condit. Reinf. active responses0.10.20.5-0.60.6-0.6-0.60.5-0.6-0.70.4-0.4-0.40.10.1-0.10.4-0.40.00.3-0.2-0.10.1-0.1-0.1
Condit. Reinf. inactive responses0.30.41.0-0.8-0.30.3-0.70.4-0.50.4-0.50.50.10.3-0.80.8-0.30.3-0.90.21.0-0.70.70.7-0.8
Condit. Reinf. lever presses3.14.214.9-3.92.4-2.3-3.73.2-3.5-1.51.3-1.3-2.4-1.80.9-0.91.8-1.51.12.3-0.41.0-1.0-0.20.2
Condit. Reinf. lever reinforcers received0.30.41.1-1.00.9-0.9-1.00.9-1.0-0.90.6-0.6-0.7-0.20.2-0.20.6-0.60.20.5-0.30.1-0.1-0.1-0.1
Conditioned reinforcement - actives2.82.83.8-1.51.6-1.6-1.41.4-1.2-1.41.4-1.4-1.8-1.51.9-1.91.9-1.91.91.7-1.61.9-1.9-1.71.7
Conditioned reinforcement - inactives0.70.71.5-0.81.1-1.1-0.80.7-0.6-0.90.7-0.7-0.9-1.21.1-1.10.9-0.50.90.4-0.70.9-0.9-0.70.6
Conditioned locomotion1.31.64.3-1.10.8-0.8-1.21.0-0.8-1.01.2-1.2-1.2-0.31.3-1.31.6-2.11.01.6-0.91.4-1.4-1.61.4
Patch foraging indifference point 0 sec0.20.31.7-0.70.4-0.4-0.80.6-0.9-0.60.7-0.7-0.4-1.30.6-0.60.10.20.20.1-0.00.2-0.20.2-0.1
Patch foraging indifference point AUC0.30.31.2-0.3-0.30.3-0.30.3-0.40.0-0.20.2-0.5-0.30.2-0.20.7-1.1-0.01.1-0.30.8-0.8-0.90.9
Delay disc. indifference point, 0s delay0.10.20.6-0.40.7-0.7-0.30.6-0.8-0.30.4-0.4-0.3-0.2-0.20.20.10.00.50.1-0.1-0.30.30.4-0.3
Delay disc. indifference point, 16s delay1.01.01.9-0.81.2-1.2-0.80.7-0.5-1.11.0-1.0-0.9-1.20.7-0.71.1-0.91.40.6-1.11.3-1.3-0.90.8
Delay disc. indifference point, 2s delay0.60.71.60.50.4-0.50.3-0.10.3-1.01.0-1.0-0.4-0.90.9-0.90.7-0.71.30.2-1.20.9-0.9-1.11.1
Delay disc. indifference point, 24s delay0.30.31.10.70.3-0.40.7-0.71.0-0.80.7-0.70.1-0.40.4-0.40.10.10.7-0.7-0.90.3-0.3-0.60.5
Delay disc. indifference point, 4s delay0.40.41.1-0.11.0-1.0-0.00.4-0.4-0.90.9-0.9-0.4-0.90.8-0.80.4-0.20.9-0.2-0.70.5-0.5-0.10.2
Delay disc. indifference point, 8s delay0.30.41.5-0.11.1-1.10.10.00.2-0.90.8-0.8-0.2-0.50.0-0.00.10.41.2-0.8-0.8-0.10.1-0.00.1
Indifference point function ln k0.30.41.20.50.5-0.50.7-0.50.6-1.11.0-1.00.3-0.40.5-0.5-0.30.80.6-1.1-0.5-0.10.10.1-0.1
Indifference point function log k0.30.41.20.50.5-0.50.7-0.50.6-1.11.0-1.00.3-0.40.5-0.5-0.30.80.6-1.1-0.5-0.10.10.1-0.1
Patch foraging total patch changes 0 sec0.30.52.3-0.90.4-0.4-1.00.8-1.1-0.60.8-0.8-0.6-1.50.7-0.70.30.00.30.40.00.4-0.40.10.1
Patch foraging total patch changes 12 sec0.50.72.0-0.90.2-0.2-1.20.9-1.2-0.60.7-0.7-0.9-1.10.6-0.60.8-1.10.31.4-0.31.0-1.0-0.70.7
Patch foraging total patch changes 18 sec1.11.44.0-1.30.5-0.6-1.51.2-1.2-0.60.7-0.7-1.4-2.01.2-1.21.2-1.41.01.5-0.81.2-1.2-1.11.3
Patch foraging total patch changes 24 sec1.61.94.1-0.80.8-0.8-1.11.1-1.1-1.31.3-1.3-1.5-1.11.4-1.41.6-2.01.11.8-1.51.7-1.7-1.81.7
Patch foraging total patch changes 6 sec0.91.45.7-2.31.0-0.9-2.41.8-2.30.2-0.00.0-1.0-2.20.2-0.20.20.2-0.30.60.80.3-0.31.0-0.8
Patch foraging time to switch 0 sec0.30.51.8-1.31.2-1.1-1.41.2-1.1-0.00.1-0.1-0.60.20.0-0.00.4-0.20.20.30.20.1-0.10.5-0.7
Patch foraging water rate 0 sec0.40.71.80.50.1-0.10.4-0.40.6-1.01.0-1.0-0.3-0.41.0-1.00.7-0.90.80.3-1.30.9-0.9-1.31.3
Patch foraging water rate 12 sec2.74.17.3-0.72.3-2.3-0.31.0-0.4-2.32.3-2.3-1.8-2.22.7-2.71.9-1.72.60.7-2.62.2-2.2-2.12.1
Patch foraging water rate 18 sec2.23.05.80.12.0-2.10.20.70.0-2.32.2-2.2-1.5-1.02.4-2.41.6-1.42.10.5-2.31.6-1.6-1.91.9
Patch foraging water rate 24 sec1.31.84.00.90.7-0.81.1-0.30.8-1.61.4-1.4-0.6-0.61.8-1.81.1-1.41.60.2-2.01.4-1.4-1.92.0
Patch foraging water rate 6 sec1.42.15.70.31.4-1.50.20.30.2-1.91.8-1.8-1.0-0.81.5-1.51.4-1.71.80.5-2.41.4-1.4-1.91.7
Seeking ratio, delayed vs. immediate footshock0.40.51.80.7-0.60.60.6-0.81.00.6-0.50.50.91.3-0.70.7-0.70.6-0.5-0.80.3-0.50.50.5-0.7
Distance traveled before self-admin3.74.06.0-1.72.0-2.0-1.51.8-1.6-2.01.9-1.9-2.1-2.02.2-2.22.2-2.32.01.8-1.92.4-2.4-1.81.8
Distance traveled after self-admin2.22.44.8-1.51.4-1.4-1.41.4-1.3-1.31.5-1.5-1.5-1.92.2-2.21.5-1.51.11.4-1.31.9-1.9-1.21.2
Extensor digitorum longus weight0.41.73.01.5-1.51.51.6-1.71.71.1-1.01.01.51.0-1.11.1-1.41.2-1.1-1.50.8-1.41.40.7-0.6
Bone: elastic displacement0.40.51.3-0.8-0.00.1-0.90.6-0.90.6-0.90.90.10.9-0.70.7-0.20.3-0.70.40.8-0.50.50.9-1.1
Bone: elastic work0.10.20.70.40.1-0.10.3-0.10.1-0.90.4-0.4-0.1-0.20.4-0.40.3-0.20.50.2-0.60.6-0.6-0.50.4
Bone: endosteal estimation0.30.62.91.6-0.70.71.7-1.31.4-0.30.1-0.10.70.2-0.10.1-0.50.4-0.0-0.9-0.4-0.10.1-0.40.4
Bone: endosteal perimeter0.61.34.82.2-1.01.02.1-1.81.70.5-0.50.51.31.8-0.70.7-0.80.7-0.6-1.2-0.2-0.70.7-0.1-0.1
Epididymis fat weight0.51.34.8-1.71.5-1.4-1.71.9-2.2-0.30.7-0.7-1.4-1.10.6-0.61.1-0.51.01.2-0.20.2-0.2-0.00.2
Delta time in closed arm before/after self-admin0.80.81.7-0.00.3-0.30.00.4-0.2-0.90.9-0.9-0.8-0.71.2-1.21.0-1.00.91.0-0.71.1-1.1-1.31.3
Delta time in open arm before/after self-admin0.90.91.50.5-0.90.90.6-1.11.10.9-0.80.81.11.0-0.90.9-1.01.0-1.0-1.20.5-1.21.20.8-0.8
Diff in mean of infusions in LGA sessions0.30.31.0-0.10.4-0.5-0.30.5-0.4-0.90.9-0.9-0.6-1.00.3-0.30.4-0.20.70.3-0.80.2-0.2-0.30.5
Delay discount exponential model param0.30.31.1-0.2-0.70.7-0.20.1-0.30.8-0.70.70.10.5-0.20.2-0.2-0.0-1.10.50.9-0.30.30.3-0.3
Extinction: sum of active levers before priming0.10.10.40.30.2-0.20.30.10.0-0.60.6-0.6-0.2-0.6-0.10.1-0.10.20.4-0.2-0.6-0.10.1-0.00.2
Active lever presses in extinction session 61.11.12.4-1.31.5-1.5-1.31.2-1.1-1.21.2-1.2-1.1-1.31.0-1.00.9-0.61.20.3-0.70.7-0.7-0.30.3
Bone: final force0.60.92.11.3-1.41.41.4-1.41.20.1-1.01.01.10.5-0.70.7-0.90.7-1.0-0.80.8-0.60.60.2-0.0
Bone: final moment0.60.92.41.4-1.31.31.6-1.41.20.0-1.01.01.10.6-0.70.7-0.90.7-0.9-0.90.6-0.60.60.1-0.0
Food consumed during 24 hour testing period0.70.81.5-0.31.2-1.2-0.20.40.1-1.01.0-1.0-0.8-0.71.1-1.10.9-0.80.90.1-1.11.2-1.2-1.00.9
Glucose0.30.41.71.3-0.70.71.0-0.80.90.10.2-0.20.20.10.3-0.30.1-0.50.10.1-0.60.5-0.5-0.91.0
Heart weight3.04.36.0-1.92.4-2.4-1.72.2-1.8-2.11.9-1.9-2.4-1.72.2-2.22.4-2.32.12.1-1.72.2-2.2-1.91.8
Delay discount hyperbolic model param0.30.31.3-0.1-0.80.8-0.10.0-0.10.8-0.80.80.20.6-0.40.4-0.30.1-1.10.30.9-0.40.40.4-0.3
Intermittent access intake day 1-15 change3.63.66.6-1.11.3-1.3-1.21.7-1.5-1.71.7-1.7-2.1-2.01.9-1.92.3-2.41.82.6-1.82.2-2.2-2.22.3
Intermittent access intake escalation2.62.65.9-0.60.8-0.8-0.71.2-1.1-1.41.2-1.2-1.7-1.41.6-1.62.0-2.21.32.4-1.62.0-2.0-2.22.2
Intermittent access intake escalation 20.80.83.00.60.1-0.10.5-0.00.2-0.70.6-0.6-0.6-0.31.1-1.11.0-1.20.81.0-1.21.1-1.1-1.61.7
Intermitt. access day 1 inactive lever presses4.34.69.02.9-2.12.13.0-3.02.91.1-1.31.32.72.1-1.91.9-2.32.1-1.8-2.81.2-2.12.11.2-1.3
Intermitt. access day 15 inactive lever presses0.60.61.30.9-1.11.10.9-1.00.90.6-0.70.70.90.6-0.70.7-0.80.7-0.8-0.60.9-0.60.60.4-0.3
Intermitt. access escalation Index3.32.96.10.9-1.31.41.1-1.20.91.8-1.71.71.70.4-1.91.9-2.12.5-1.7-2.01.9-1.91.92.2-2.0
Intermittent access day 1 total infusions0.20.31.0-0.80.8-0.8-0.60.3-0.2-0.70.6-0.6-0.3-1.00.4-0.40.20.00.6-0.5-0.30.2-0.20.1-0.1
Intermittent access day 15 total infusions1.41.63.9-1.21.2-1.2-1.01.2-1.0-1.31.2-1.2-1.3-2.01.3-1.31.3-1.21.21.1-1.01.4-1.4-1.11.1
Intermittent access terminal intake (last 3 days)1.01.13.4-0.51.2-1.2-0.40.6-0.3-1.31.2-1.2-0.9-1.81.3-1.30.9-0.61.30.1-1.11.0-1.0-0.91.0
Intermittent access total infusions1.01.13.0-0.71.3-1.4-0.50.6-0.2-1.41.3-1.3-0.9-1.71.2-1.20.9-0.51.30.0-1.21.0-1.0-0.80.9
Intermittent access day 1 locomotion0.20.20.9-0.40.4-0.5-0.2-0.10.1-0.90.9-0.9-0.1-0.40.3-0.30.2-0.30.3-0.3-0.40.2-0.2-0.30.2
Intermittent access day 15 total locomotion2.02.24.9-1.61.1-1.1-1.61.5-1.5-1.31.3-1.3-1.6-0.91.2-1.21.9-2.21.02.1-1.21.6-1.6-1.51.3
Intermittent access total locomotion1.82.03.7-0.91.3-1.3-0.90.9-0.6-1.81.9-1.9-1.3-1.21.5-1.51.5-1.61.41.0-1.61.5-1.5-1.61.5
Intermittent access standard deviation0.10.10.4-0.1-0.50.6-0.10.0-0.10.2-0.30.30.00.3-0.10.10.1-0.3-0.40.60.50.1-0.1-0.10.2
Left kidney weight0.10.21.6-0.4-0.10.2-0.40.5-0.90.1-0.20.2-0.40.40.2-0.20.6-0.60.11.30.00.4-0.4-0.50.4
Right kidney weight0.20.61.8-0.4-0.40.5-0.70.7-1.21.3-1.31.3-0.10.9-0.70.70.0-0.0-0.91.11.1-0.50.50.5-0.5
Cocaine induced anxiety0.40.51.20.9-0.70.70.9-0.90.90.8-0.60.60.91.1-0.50.5-0.60.4-0.5-0.70.5-0.50.50.3-0.4
Post-drug Anxiety0.60.71.81.2-0.50.51.3-1.21.30.3-0.40.41.01.2-0.70.7-0.90.8-0.3-1.30.2-0.80.80.5-0.6
Baseline Anxiety0.40.40.70.5-0.30.30.6-0.40.50.3-0.50.50.60.8-0.80.8-0.70.8-0.6-0.80.4-0.80.80.8-0.8
Tail length0.31.02.4-0.0-0.90.9-0.0-0.2-0.31.3-1.41.40.70.4-1.01.0-0.91.0-1.1-0.41.5-1.21.21.2-1.1
Length with tail0.00.10.30.3-0.00.00.20.1-0.40.4-0.50.50.00.4-0.20.2-0.10.20.0-0.00.2-0.60.60.2-0.2
Length without tail0.51.12.80.21.2-1.20.20.5-0.2-1.11.1-1.1-1.0-0.11.2-1.21.2-1.11.50.6-1.71.0-1.0-1.31.3
Times rat made contact with spout0.40.51.4-0.30.1-0.0-0.0-0.10.10.4-0.30.30.4-0.1-0.80.8-0.81.2-0.5-1.00.6-1.01.01.2-1.1
Lifetime Intake1.21.33.1-1.41.5-1.5-1.11.1-0.8-1.31.2-1.2-1.2-1.81.2-1.21.1-0.71.40.5-1.01.1-1.1-0.70.7
Liver weight, left0.20.41.30.30.2-0.20.10.3-0.3-0.10.6-0.6-0.50.10.6-0.60.7-1.10.51.0-0.70.7-0.7-0.90.9
Liver weight, right0.91.55.11.1-1.61.60.8-0.50.11.6-1.51.50.72.3-1.61.6-0.5-0.3-1.50.70.9-1.31.30.3-0.4
Locomotor activity0.20.41.5-1.0-0.10.1-1.00.8-1.00.6-0.60.6-0.5-0.10.2-0.20.6-0.8-0.31.20.70.5-0.5-0.20.2
Locomotor testing distance0.61.02.9-0.70.2-0.2-0.80.6-0.5-0.30.2-0.2-0.9-0.31.3-1.31.3-1.70.51.6-0.51.3-1.3-1.61.4
Locomotor testing rearing0.30.41.1-0.2-1.01.0-0.2-0.0-0.20.9-1.01.00.10.9-0.70.70.1-0.6-1.00.80.8-0.40.4-0.20.1
Locomotion in novel chamber0.81.03.2-1.20.3-0.3-1.31.1-1.3-0.50.5-0.5-1.1-1.30.3-0.31.2-1.40.41.8-0.21.2-1.2-1.01.0
Locomotion in novel chamber post-restriction0.20.31.1-1.1-0.10.1-1.00.4-0.70.6-0.60.6-0.1-0.6-0.10.1-0.10.3-0.5-0.01.1-0.20.20.5-0.3
Fecal boli incidents, locomotor time 11.51.72.6-0.61.5-1.5-0.71.1-0.8-1.61.6-1.6-1.3-1.11.5-1.51.3-1.31.40.9-1.21.4-1.4-1.11.1
Change in fecal boli incidents, locomotor task0.40.41.8-1.40.4-0.3-1.20.9-1.10.4-0.40.4-0.5-0.40.3-0.30.4-0.20.10.80.30.1-0.10.2-0.2
Time >=10cm from walls, locomotor time 12.02.05.62.3-1.51.52.2-2.02.01.2-1.11.11.72.4-1.11.1-1.40.9-0.8-1.50.6-0.90.90.5-0.6
Bouts of movement, locomotor time 10.91.02.5-0.6-0.40.5-0.3-0.30.10.7-0.70.70.80.2-1.11.1-1.21.5-1.1-1.11.3-1.21.21.6-1.6
Total resting periods, locomotor time 10.80.92.4-0.8-0.40.4-0.5-0.1-0.10.6-0.60.60.70.2-1.11.1-1.11.4-1.0-0.91.3-1.21.21.5-1.5
Rest time, locomotor task time 10.40.41.4-1.20.9-0.9-1.20.9-0.7-0.60.6-0.6-0.6-0.60.6-0.60.4-0.40.30.20.00.4-0.40.2-0.3
Distance moved, locomotor task time 11.21.44.11.9-2.02.01.9-1.61.31.2-1.31.31.11.1-0.80.8-0.50.0-0.90.10.2-0.30.3-0.50.6
Vertical activity count, locomotor time 10.40.42.01.4-0.90.91.3-0.90.90.4-0.40.40.50.30.1-0.1-0.20.0-0.20.0-0.3-0.10.1-0.50.7
Time >=10cm from walls, locomotor time 20.20.30.5-0.20.7-0.7-0.20.3-0.1-0.60.7-0.7-0.3-0.40.6-0.60.3-0.10.7-0.1-0.70.7-0.7-0.10.1
Bouts of movement, locomotor time 22.02.27.41.6-0.80.71.7-1.92.00.3-0.30.31.70.9-1.51.5-1.82.1-0.7-2.70.5-1.81.81.3-1.3
Total resting periods, locomotor time 21.81.97.71.6-0.40.41.8-1.82.00.0-0.00.01.60.8-1.21.2-1.72.0-0.4-2.80.2-1.61.61.2-1.3
Rest time, locomotor task time 20.30.41.30.9-0.10.20.7-0.70.70.4-0.40.40.80.6-0.20.2-0.70.8-0.3-1.10.4-0.60.60.8-0.8
Distance moved, locomotor task time 20.30.42.3-1.0-0.20.2-0.90.7-0.80.1-0.00.0-0.6-0.4-0.20.20.7-0.9-0.21.50.10.5-0.5-0.60.5
Vertical activity count, locomotor time 20.10.10.5-0.6-0.40.4-0.50.3-0.40.4-0.40.4-0.1-0.1-0.30.30.1-0.1-0.50.70.5-0.30.30.00.0
Light reinforcement 10.30.63.2-1.70.8-0.8-1.81.3-1.5-0.10.3-0.3-0.8-0.30.2-0.20.5-0.20.00.80.30.1-0.10.3-0.4
Light reinforcement 20.20.31.10.60.0-0.00.7-0.60.70.4-0.10.10.60.7-0.30.3-0.60.9-0.3-1.00.1-0.50.50.5-0.6
Bone: marrow area0.30.63.01.6-0.80.71.7-1.41.4-0.20.1-0.10.70.2-0.10.1-0.50.4-0.1-0.9-0.4-0.10.1-0.40.5
Bone: maximum diameter2.13.812.63.6-2.22.13.3-3.02.91.0-1.31.32.32.9-1.41.4-1.61.0-1.3-1.90.2-1.31.30.1-0.3
Bone: maximum force0.91.54.72.1-1.81.82.2-1.91.80.2-1.01.01.41.1-0.80.8-1.00.6-1.0-0.90.5-0.70.7-0.10.2
Bone: maximum moment0.91.65.32.2-1.71.62.3-1.91.80.1-0.90.91.41.2-0.80.8-1.00.6-1.0-1.00.4-0.80.8-0.10.1
Mean time between licks in bursts1.72.34.41.4-1.31.31.0-0.80.61.3-2.12.11.21.3-1.61.6-1.51.4-1.8-1.11.7-2.12.11.5-1.4
Mean num. licks in bursts1.01.21.80.3-1.01.00.6-1.00.91.1-1.31.31.21.0-1.41.4-1.21.2-1.2-1.11.0-1.01.01.1-1.2
Cd content in liver0.40.41.2-0.60.0-0.0-0.70.7-0.9-0.40.0-0.0-0.8-0.90.6-0.60.7-0.90.21.10.10.4-0.4-0.70.9
Co content in liver1.31.53.40.80.9-1.01.0-0.51.1-1.21.5-1.5-0.4-0.51.7-1.70.8-0.91.4-0.3-1.81.4-1.4-1.61.5
Cu content in liver0.10.10.40.5-0.60.60.6-0.50.60.40.2-0.20.2-0.50.0-0.0-0.20.10.0-0.2-0.00.0-0.0-0.30.5
Fe content in liver0.60.71.1-0.80.6-0.6-0.80.9-0.9-0.51.0-1.0-0.9-0.91.0-1.00.9-0.90.81.0-0.61.0-1.0-0.70.9
K content in liver2.52.44.41.4-1.41.41.5-1.61.51.4-1.51.51.72.1-1.71.7-1.61.5-1.3-1.61.0-1.91.91.3-1.4
Mg content in liver1.61.63.10.3-1.11.20.2-0.50.21.5-1.51.51.01.8-1.61.6-1.21.0-1.5-0.51.4-1.71.71.4-1.5
Mn content in liver1.21.32.80.7-1.51.50.7-0.90.51.4-1.71.71.10.6-1.31.3-1.11.0-1.2-0.61.2-1.31.30.9-0.8
Na content in liver2.93.08.6-0.5-0.20.3-0.60.2-0.71.3-1.81.81.02.1-2.42.4-1.61.8-1.9-1.21.8-2.42.42.6-2.9
Rb content in liver0.20.31.00.30.5-0.50.2-0.10.3-0.50.6-0.6-0.20.30.7-0.70.4-0.70.8-0.1-1.00.2-0.2-0.70.6
Se content in liver1.31.64.0-1.3-0.80.9-1.51.0-1.82.0-1.51.50.00.4-1.41.4-0.40.5-1.21.11.8-1.11.11.4-1.3
Sr content in liver0.10.10.4-0.60.2-0.2-0.30.4-0.4-0.10.3-0.3-0.3-0.50.1-0.10.2-0.10.20.3-0.00.2-0.2-0.00.1
Zn content in liver0.20.31.0-0.2-0.30.4-0.2-0.0-0.11.0-0.70.70.30.7-0.50.5-0.40.3-0.6-0.10.7-0.50.50.6-0.7
Bone: minimum diameter0.91.85.12.2-1.71.62.2-2.01.80.7-0.90.91.51.8-1.11.1-1.00.7-1.1-1.20.3-0.90.9-0.0-0.0
Time in familiar zone, hab. session 10.70.61.40.50.3-0.30.10.5-0.4-1.00.8-0.8-0.8-0.80.7-0.70.9-0.91.01.1-1.10.8-0.8-1.11.2
Time in novel zone, hab. session 11.41.42.20.3-1.01.00.6-1.00.81.4-1.41.41.21.4-1.21.2-1.21.0-1.5-1.11.3-1.21.21.1-1.3
Total zone transitions, hab. session 12.12.95.8-1.61.6-1.6-1.61.9-2.0-1.61.4-1.4-2.0-0.71.6-1.62.2-2.41.42.4-1.41.5-1.5-1.71.6
Total locomotion distance, hab. session 10.40.62.3-1.10.5-0.4-1.11.0-1.1-0.10.1-0.1-0.80.30.6-0.61.0-1.20.41.5-0.30.5-0.5-0.70.5
Locomotion velocity, hab. session 10.70.92.5-1.30.8-0.8-1.31.2-1.3-0.40.5-0.5-1.1-0.20.9-0.91.3-1.40.71.6-0.50.8-0.8-0.90.7
Time in familiar zone, hab. session 20.40.41.80.8-1.41.30.5-0.50.50.20.0-0.00.2-0.0-0.30.30.2-0.6-0.10.9-0.10.4-0.4-0.81.0
Time in novel zone, hab. session 20.50.52.6-0.81.6-1.6-0.50.5-0.4-0.90.6-0.6-0.5-0.40.8-0.80.20.20.6-0.8-0.40.1-0.10.3-0.4
Total zone transitions, hab. session 20.30.41.0-0.7-0.20.3-0.50.2-0.41.0-0.80.80.20.9-0.70.7-0.3-0.0-0.70.00.8-0.80.80.6-0.7
Total locomotion distance, hab. session 20.91.12.8-0.2-0.80.90.1-0.50.21.7-1.71.70.91.6-1.21.2-0.80.5-1.2-0.41.3-1.01.01.0-1.2
Locomotion velocity, hab. session 20.60.92.5-0.2-0.60.6-0.0-0.30.11.6-1.51.50.71.5-1.01.0-0.60.3-1.0-0.31.1-0.90.90.8-1.1
Novel to familiar place preference ratio1.31.32.60.3-0.80.80.2-0.60.11.3-1.21.21.11.1-1.21.2-1.31.4-1.3-1.11.4-1.41.41.6-1.6
Novelty place preference1.71.73.20.4-0.90.90.4-0.80.31.4-1.31.31.31.3-1.41.4-1.51.6-1.5-1.41.5-1.61.61.8-1.8
Time in novel zone, NPP test1.71.73.00.6-0.90.90.5-0.90.51.3-1.31.31.31.4-1.31.3-1.61.6-1.5-1.41.4-1.61.61.7-1.7
Total zone transitions, NPP test0.50.71.4-1.11.0-1.0-0.80.8-0.7-0.70.8-0.8-1.0-0.60.9-0.91.0-1.20.60.7-0.70.8-0.8-0.90.7
Total locomotion distance, NPP test0.20.31.1-1.1-0.30.3-0.90.5-0.80.8-0.80.8-0.20.2-0.30.30.2-0.5-0.60.80.80.1-0.10.2-0.3
Locomotion velocity, NPP test0.20.31.0-0.9-0.50.5-0.70.3-0.61.0-1.01.00.00.2-0.40.40.0-0.4-0.70.70.90.1-0.10.2-0.3
Intraocular pressure0.50.72.01.20.5-0.61.1-0.51.0-1.01.0-1.0-0.1-0.80.6-0.60.10.21.1-0.9-1.40.1-0.1-0.70.9
Delta distance traveled before/after self-admin0.20.20.70.4-0.80.90.3-0.40.30.6-0.40.40.50.00.0-0.0-0.40.4-0.70.10.60.0-0.00.2-0.1
Delta ambulatory time before/after self-admin1.11.22.50.6-1.21.30.5-0.80.51.6-1.31.31.20.6-0.80.8-1.21.4-1.5-0.71.5-1.01.01.3-1.2
Parametrial fat weight0.10.20.80.8-0.40.30.9-0.70.40.3-0.20.20.70.3-0.40.4-0.60.4-0.5-0.80.4-0.10.10.4-0.5
Pavlov. Cond. lever latency0.50.61.7-0.0-0.60.60.0-0.40.20.7-0.60.60.7-0.3-0.70.7-1.01.1-0.9-0.91.3-0.70.71.2-1.1
Pavlov. Cond. magazine entry latency0.20.31.7-0.2-0.30.3-0.40.3-0.50.7-0.60.6-0.11.3-0.60.60.2-0.3-0.60.80.2-0.50.50.0-0.2
Pavlov. Cond. change in total contacts0.10.10.80.3-0.30.30.2-0.0-0.0-0.1-0.00.00.00.9-0.50.50.1-0.1-0.30.4-0.1-0.40.4-0.10.0
Pavlov. Cond. index score0.10.20.80.0-0.0-0.0-0.10.2-0.20.20.0-0.0-0.30.90.0-0.00.6-0.60.10.8-0.50.0-0.0-0.60.5
Pavlov. Cond. latency score0.10.10.50.10.2-0.2-0.00.2-0.1-0.10.2-0.2-0.30.70.1-0.10.5-0.50.30.6-0.70.1-0.1-0.70.5
Pavlov. Cond. lever contacts0.20.21.80.6-0.50.40.5-0.30.30.3-0.20.20.21.3-0.40.40.1-0.2-0.30.3-0.3-0.40.4-0.30.2
Pavlov. Cond. magazine entry number0.20.21.50.20.3-0.30.4-0.30.5-0.60.4-0.40.2-1.20.4-0.4-0.30.40.4-0.9-0.10.4-0.40.2-0.0
Pavlov. Cond. intertrial magazine entries1.11.32.50.4-0.90.90.4-0.80.71.2-1.11.11.20.5-1.21.2-1.41.6-1.2-1.41.4-1.21.21.5-1.5
Pavlov. Cond. lever-magazine prob. diff.0.10.11.10.1-0.20.2-0.00.1-0.10.2-0.10.1-0.21.1-0.20.20.4-0.5-0.00.7-0.4-0.20.2-0.50.4
Pavlov. Cond. response bias0.20.32.6-0.1-0.30.3-0.30.3-0.40.5-0.40.4-0.21.6-0.30.30.5-0.7-0.21.2-0.2-0.20.2-0.40.2
Pavlov. Cond. lever latency1.92.610.43.2-1.61.53.0-2.63.00.8-0.70.71.90.8-0.40.4-1.51.4-0.5-2.20.0-0.70.70.10.1
Pavlov. Cond. magazine entry latency0.50.62.2-1.50.8-0.8-1.51.2-1.4-0.80.5-0.5-0.8-0.4-0.10.10.6-0.60.30.9-0.10.2-0.20.2-0.3
Pavlov. Cond. change in total contacts1.01.45.4-2.31.2-1.1-2.32.0-2.3-0.60.6-0.6-1.3-0.4-0.20.21.0-1.10.21.6-0.10.3-0.30.1-0.3
Pavlov. Cond. index score1.72.18.1-2.81.6-1.5-2.72.4-2.7-1.00.8-0.8-1.7-0.50.2-0.21.3-1.40.52.0-0.30.5-0.5-0.0-0.2
Pavlov. Cond. latency score1.72.27.2-2.71.7-1.6-2.52.3-2.6-1.10.9-0.9-1.7-0.50.4-0.41.5-1.50.72.0-0.60.7-0.7-0.30.1
Pavlov. Cond. lever contacts2.53.412.8-3.61.9-1.8-3.53.0-3.4-1.10.9-0.9-2.1-0.90.5-0.51.7-1.60.62.5-0.10.6-0.6-0.1-0.1
Pavlov. Cond. magazine entry number0.50.62.41.5-0.80.71.5-1.21.50.5-0.30.30.7-0.00.3-0.3-0.50.5-0.1-0.9-0.10.1-0.1-0.30.5
Pavlov. Cond. intertrial magazine entries0.40.52.21.4-0.90.91.5-1.21.40.6-0.20.20.60.50.5-0.5-0.20.1-0.1-0.3-0.10.2-0.2-0.60.7
Pavlov. Cond. lever-magazine prob. diff.1.82.28.1-2.81.6-1.5-2.72.5-2.8-1.00.8-0.8-1.7-0.70.2-0.21.4-1.40.62.0-0.30.6-0.6-0.1-0.1
Pavlov. Cond. response bias1.92.510.0-3.21.6-1.5-3.12.7-3.1-1.10.8-0.8-1.8-0.90.3-0.31.3-1.20.42.10.10.4-0.40.1-0.2
Time in closed arm before self-admin0.40.50.70.5-0.70.70.1-0.60.50.8-0.80.80.80.6-0.60.6-0.80.8-0.8-0.80.7-0.80.80.9-0.8
Time in closed arm after self-admin0.20.20.70.3-0.50.50.1-0.10.00.0-0.00.0-0.10.20.4-0.40.4-0.70.10.80.10.5-0.5-0.60.6
Time in open arm before self-admin0.80.92.1-0.40.6-0.7-0.10.7-0.8-0.90.9-0.9-0.9-0.90.8-0.81.1-1.11.01.2-0.91.4-1.4-1.11.1
Time in open arm after self-admin0.20.20.70.6-0.10.10.8-0.70.7-0.30.3-0.30.4-0.00.0-0.0-0.30.60.1-0.8-0.4-0.40.4-0.00.2
Bone: periosteal estimation0.81.65.92.4-1.61.52.4-2.12.00.2-0.60.61.41.2-0.80.8-1.00.8-0.7-1.30.1-0.80.8-0.20.2
Bone: periosteal perimeter0.91.54.62.0-1.51.41.9-1.71.50.7-1.11.11.42.1-1.01.0-0.90.5-1.1-0.90.3-0.90.90.1-0.2
Bone: post-yield work0.50.61.91.2-0.60.51.3-1.01.4-0.60.6-0.60.2-0.00.5-0.50.2-0.50.5-0.1-0.90.5-0.5-1.21.4
Progressive ratio test 1 active lever presses0.70.72.4-1.51.0-0.9-1.31.0-1.0-0.70.8-0.8-0.9-1.50.7-0.70.6-0.50.70.4-0.30.5-0.5-0.10.2
Progressive ratio test 1 breakpoint0.50.62.3-1.50.9-0.9-1.30.9-1.0-0.60.7-0.7-0.7-1.50.5-0.50.4-0.10.60.1-0.10.2-0.20.2-0.1
Progressive ratio test 1 inactive lever presses0.50.61.00.3-0.70.70.4-0.80.80.3-0.40.40.90.7-0.80.8-0.90.7-1.0-1.00.8-1.01.00.7-0.8
Progressive ratio test 2 active lever presses0.70.81.9-0.91.0-1.0-0.80.8-0.7-1.21.1-1.1-0.9-1.40.8-0.80.8-0.40.80.5-0.70.7-0.7-0.50.6
Progressive ratio test 2 breakpoint0.70.82.1-0.91.1-1.1-0.70.8-0.6-1.21.2-1.2-0.9-1.50.9-0.90.8-0.51.00.4-0.90.7-0.7-0.60.7
Progressive ratio test 2 inactive lever presses0.10.10.60.4-0.10.10.5-0.60.7-0.70.2-0.20.3-0.20.1-0.1-0.30.3-0.1-0.80.0-0.10.1-0.10.1
Incentive Sensitization - Responses0.30.41.0-0.10.6-0.6-0.00.3-0.3-0.90.8-0.8-0.5-1.00.6-0.60.6-0.20.50.3-0.70.7-0.7-0.60.6
Incentive Sensitization - Breakpoint0.50.51.1-0.10.7-0.70.00.4-0.3-1.00.9-0.9-0.6-1.00.8-0.80.7-0.30.60.4-0.80.8-0.8-0.70.7
Sum of active levers in priming session hrs 5-60.60.61.0-0.60.7-0.7-0.90.7-0.8-0.91.0-1.0-0.9-0.60.5-0.50.9-1.00.80.7-1.00.2-0.2-0.80.8
Progressive ratio0.10.10.50.3-0.70.70.3-0.60.60.0-0.10.10.50.4-0.40.4-0.3-0.0-0.4-0.30.2-0.20.2-0.0-0.0
Food seeking constrained by brief footshock3.34.17.3-1.12.1-2.1-1.01.3-0.8-2.52.5-2.5-1.9-2.22.7-2.71.9-1.92.31.0-2.22.0-2.0-1.92.0
Seeking ratio, punishment vs. effort1.92.34.0-0.91.6-1.7-0.81.2-0.9-1.51.6-1.6-1.6-1.92.0-2.01.6-1.31.71.1-1.51.6-1.6-1.41.5
Retroperitoneal fat weight0.20.51.40.1-0.30.3-0.00.2-0.71.0-0.90.90.3-0.3-0.70.7-0.61.0-0.5-0.31.2-0.80.81.1-0.9
Reaction time number correct0.91.42.5-1.51.6-1.5-1.51.6-1.5-0.50.7-0.7-1.3-0.21.3-1.31.4-1.20.81.4-0.61.0-1.0-0.60.4
Reaction time mean minus median2.12.85.11.4-2.22.31.1-1.41.41.9-2.02.01.72.0-1.81.8-1.61.3-1.9-0.71.7-1.61.61.1-1.1
Reaction time mean minus median AUC2.83.66.81.7-2.62.61.4-1.81.71.9-2.12.12.02.3-2.02.0-1.91.7-2.1-1.01.8-2.02.01.3-1.2
Reaction time num false alarms0.30.41.41.1-0.90.91.2-0.91.1-0.2-0.20.20.4-0.40.3-0.3-0.2-0.0-0.0-0.1-0.00.4-0.4-0.60.8
Reaction time num false alarms AUC0.50.61.81.2-0.70.71.4-0.91.2-0.50.2-0.20.2-0.70.8-0.80.2-0.40.40.0-0.50.9-0.9-1.21.4
Reaction time trials correct on left0.91.42.5-1.51.6-1.5-1.51.6-1.5-0.50.7-0.7-1.3-0.21.3-1.31.4-1.20.81.4-0.61.0-1.0-0.60.4
Reaction time trials on left0.81.12.4-1.51.4-1.3-1.51.5-1.5-0.40.5-0.5-1.2-0.11.1-1.11.3-1.10.71.4-0.50.9-0.9-0.50.3
Reaction time mean2.63.67.51.6-2.72.71.3-1.81.62.3-2.12.12.01.3-2.02.0-2.01.8-2.1-1.01.9-1.81.81.4-1.1
Reaction time mean AUC3.24.39.11.9-3.03.01.6-2.01.82.5-2.22.22.21.6-2.22.2-2.11.9-2.3-1.12.1-2.02.01.5-1.2
Median of all reaction times1.82.55.81.4-2.42.41.1-1.51.32.0-1.71.71.70.8-1.61.6-1.61.5-1.8-0.81.7-1.51.51.2-0.8
Reaction time omissions4.35.910.61.0-3.23.30.4-1.20.53.1-3.03.02.02.1-3.13.1-2.22.0-3.0-0.43.0-2.72.72.2-2.0
Reaction time false alarm rate0.60.93.81.8-1.41.31.9-1.61.8-0.3-0.10.10.8-0.5-0.00.0-0.70.4-0.0-0.9-0.10.1-0.1-0.50.8
Reaction time premature initiation rate0.20.20.8-0.90.4-0.4-0.80.3-0.50.6-0.20.20.00.1-0.20.2-0.30.70.0-0.40.4-0.30.30.8-0.7
Reaction time premature initiations0.30.42.0-1.41.1-1.0-1.30.9-1.00.20.2-0.2-0.60.00.5-0.50.30.10.50.3-0.10.2-0.20.3-0.4
Std. dev. reaction times3.75.29.61.9-3.13.11.6-2.12.02.5-2.62.62.42.2-2.42.4-2.32.1-2.5-1.32.3-2.32.31.7-1.6
Reaction time trials completed0.81.12.4-1.51.4-1.3-1.51.5-1.5-0.40.5-0.5-1.2-0.11.1-1.11.3-1.10.71.4-0.50.9-0.9-0.50.3
Reaction time trials AUC1.01.52.8-1.61.6-1.5-1.61.7-1.5-0.60.7-0.7-1.4-0.31.3-1.31.4-1.20.91.5-0.61.1-1.1-0.70.5
Run reversals in cocaine runway, females0.10.10.50.70.0-0.00.7-0.40.50.2-0.20.20.30.5-0.10.1-0.30.2-0.0-0.50.30.4-0.40.2-0.3
Run reversals in cocaine runway, males0.30.20.90.1-0.40.40.2-0.60.70.4-0.50.50.61.0-0.30.3-0.50.5-0.5-0.70.4-0.50.50.4-0.5
Latency to leave start box in cocaine runway2.22.43.8-1.12.0-2.0-1.11.2-0.8-1.81.7-1.7-1.5-0.21.8-1.81.8-1.91.81.1-1.71.6-1.6-1.51.3
Latency to leave start box in cocaine runway, F2.32.53.5-1.81.7-1.7-1.81.6-1.5-1.11.3-1.3-1.7-0.61.8-1.81.9-1.81.61.7-1.41.7-1.7-1.41.1
Latency to leave start box in cocaine runway, M0.30.30.90.60.5-0.60.6-0.30.5-0.80.5-0.5-0.11.00.4-0.40.3-0.80.4-0.3-0.50.3-0.3-0.60.3
Std. dev. time between licks in bursts2.22.63.91.5-1.81.81.3-1.51.01.3-1.71.71.71.4-1.91.9-1.71.6-2.0-1.41.6-1.91.91.4-1.4
Total sessions with >9 infusions0.30.42.0-1.40.7-0.7-1.10.8-0.8-0.50.7-0.7-0.5-0.60.1-0.10.20.00.60.2-0.3-0.00.00.3-0.3
Short access day 1 total inactive lever presses0.60.61.5-0.30.4-0.5-0.20.1-0.0-1.21.1-1.1-0.5-0.60.9-0.90.8-1.00.50.5-0.71.1-1.1-1.11.0
Short access day 10 total inactive lever presses1.82.03.31.4-1.51.51.4-1.51.31.1-1.41.41.61.2-1.51.5-1.51.4-1.8-1.51.4-1.41.41.1-1.2
Short access day 1 total infusions0.20.21.9-1.40.4-0.3-1.00.4-0.50.1-0.10.1-0.1-0.60.0-0.0-0.00.30.1-0.20.20.0-0.00.5-0.5
Short access day 10 total infusions2.22.55.6-2.01.8-1.7-2.11.9-1.8-1.51.4-1.4-1.7-2.41.5-1.51.5-1.31.61.3-0.91.4-1.4-0.80.8
Short access total infusions0.40.52.5-1.60.8-0.8-1.30.9-0.9-0.40.4-0.4-0.6-0.90.5-0.50.5-0.20.70.4-0.20.4-0.40.0-0.0
Short access day 1 locomotion0.70.71.80.2-0.50.60.1-0.70.40.9-0.60.61.00.3-0.80.8-1.11.3-0.7-1.40.9-1.01.01.2-1.2
Short access day 10 total locomotion2.22.54.5-1.21.3-1.4-1.41.2-0.8-1.92.1-2.1-1.5-1.51.5-1.51.8-2.01.51.4-1.41.7-1.7-1.61.5
Short access total locomotion0.60.61.5-1.10.9-0.9-1.10.8-0.7-1.01.2-1.2-0.7-0.90.6-0.60.7-0.70.70.5-0.60.6-0.6-0.40.3
One hour access (0.3 mA shock)0.91.11.9-1.01.2-1.2-0.91.0-0.8-1.11.1-1.1-1.1-1.41.0-1.01.2-1.11.00.9-0.91.1-1.1-0.90.8
Compulsive drug intake0.20.20.70.4-0.70.70.3-0.30.30.3-0.20.20.20.8-0.40.40.1-0.6-0.70.50.10.1-0.1-0.50.3
One hour access (shock baseline)0.80.92.3-0.81.4-1.4-0.70.8-0.4-1.31.1-1.1-0.9-1.51.1-1.10.7-0.31.3-0.0-1.00.7-0.7-0.40.5
Social response proportion0.20.20.50.1-0.40.40.1-0.20.00.5-0.60.60.30.7-0.60.6-0.30.4-0.3-0.10.5-0.50.50.3-0.4
Social responses0.70.91.8-0.2-1.01.0-0.3-0.1-0.31.1-1.21.20.61.3-1.21.2-0.60.6-1.30.21.3-0.90.90.9-1.0
Social time0.30.52.0-1.40.5-0.4-1.11.0-0.80.30.1-0.1-0.7-0.30.7-0.70.7-0.50.51.10.10.6-0.6-0.30.3
Soleus weight7.221.032.9-2.05.0-5.1-2.03.4-2.1-5.75.6-5.6-4.8-3.95.0-5.04.9-4.85.43.2-5.64.4-4.4-4.94.8
Bone: stiffness2.53.910.42.9-2.52.43.2-3.03.10.9-1.41.42.41.8-1.51.5-1.91.5-1.5-2.20.9-1.51.50.5-0.3
Tibialis anterior weight0.93.14.9-1.11.3-1.4-1.11.4-1.1-1.81.9-1.9-1.9-2.21.9-1.91.9-1.92.01.7-1.91.8-1.8-1.92.1
Time to tail flick, vehicle, before self-admin1.92.03.6-0.51.6-1.6-0.61.1-0.9-1.91.9-1.9-1.5-0.61.3-1.31.6-1.51.61.4-1.81.2-1.2-1.61.4
Time to tail flick, vehicle, after self-admin1.31.42.6-0.60.6-0.6-0.50.9-0.8-1.01.2-1.2-1.2-1.21.0-1.01.3-1.61.41.6-1.51.3-1.3-1.41.6
Time to tail flick, test, before self-admin0.70.61.6-0.61.2-1.3-0.51.0-0.7-0.90.8-0.8-1.0-0.50.8-0.80.9-0.70.60.6-0.60.8-0.8-0.60.5
Time to tail flick, test, after self-admin1.81.83.4-0.81.6-1.6-0.50.9-0.5-1.81.9-1.9-1.3-1.31.5-1.51.2-1.01.60.5-1.61.3-1.3-1.21.2
Delta time to tail flick, vehicle, before/after SA0.50.50.90.3-0.90.90.5-0.60.60.9-0.80.80.80.0-0.60.6-1.00.9-0.6-0.80.6-0.70.70.9-0.6
Delta time to tail flick, test, before/after SA0.30.30.7-0.50.5-0.5-0.40.2-0.1-0.80.8-0.8-0.4-0.80.5-0.50.4-0.10.8-0.0-0.70.4-0.4-0.40.4
Tibia length0.20.51.2-0.31.0-1.0-0.71.0-1.0-1.10.7-0.7-0.8-0.60.8-0.80.8-0.70.70.7-0.50.4-0.4-0.30.3
Ambulatory time before self-admin2.62.74.2-1.61.7-1.7-1.41.5-1.3-1.71.6-1.6-1.7-1.61.8-1.81.7-1.71.71.3-1.42.1-2.1-1.41.4
Ambulatory time after self-admin0.50.61.5-1.10.7-0.6-0.90.6-0.6-0.40.5-0.5-0.6-1.01.2-1.20.6-0.50.40.5-0.41.2-1.2-0.30.3
Bone: tissue strength0.60.51.30.40.6-0.70.20.3-0.1-0.90.8-0.8-0.70.20.7-0.70.9-1.10.60.8-1.10.7-0.7-1.10.9
Total heroin consumption0.20.21.00.10.3-0.3-0.20.3-0.0-0.60.8-0.8-0.5-1.00.3-0.30.2-0.00.6-0.1-0.4-0.10.1-0.20.5
Bone: trabecular number0.91.52.5-1.01.0-1.0-1.31.2-1.1-1.51.1-1.1-1.4-1.01.1-1.11.4-1.61.11.6-0.91.2-1.2-1.31.3
Bone: trabecular spacing0.71.02.30.7-1.01.01.2-1.31.20.8-0.80.81.20.3-0.90.9-1.31.1-0.9-1.50.7-0.80.80.8-0.7
Bone: trabecular thickness0.40.51.90.10.3-0.30.30.10.1-0.71.0-1.0-0.5-1.40.8-0.80.4-0.30.80.1-0.70.6-0.6-0.71.0
Bone: trabecular tissue density0.60.82.00.6-1.41.40.6-0.70.41.4-1.11.10.90.7-1.01.0-0.80.5-1.2-0.21.2-0.90.90.7-0.5
Water consumed over 24 hours0.10.10.70.4-0.10.10.4-0.50.60.2-0.00.00.4-0.2-0.20.2-0.40.6-0.3-0.90.3-0.20.20.2-0.2
Number of responses in last shaping day1.11.13.1-0.81.3-1.3-0.80.7-0.1-1.81.7-1.7-0.9-0.61.0-1.00.8-0.71.40.2-1.40.7-0.7-0.80.7