Hub : Genes

Pcgf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg mRNA stability Pcgf5 0.15 0.09 5.9e-03 0.03 0.09 0.05 0.04 5.0e-02 3.0e-03 2.2e-02 3.1e-02
2 Liver isoform ratio NM_001129882.1 0.05 0.03 2.3e-05 0.03 0.03 0.02 0.03 1.3e-04 5.4e-04 1.0e-03 7.0e-04
3 PL gene expression Pcgf5 0.07 0.04 5.0e-07 0.07 0.06 0.06 0.06 4.4e-08 3.5e-07 9.0e-07 2.2e-07
4 Liver alternative polyA XM_017589708.3 0.05 0.03 1.9e-06 0.04 0.04 0.03 0.03 4.8e-05 2.2e-05 1.4e-04 1.2e-04
5 Brain mRNA stability Pcgf5 0.03 0.02 5.4e-03 0 0.02 0 0.01 3.2e-01 6.1e-03 1.3e-01 8.2e-02
6 Liver alternative polyA NM_001129882.1 0.05 0.03 2.9e-06 0.04 0.04 0.03 0.03 7.1e-05 3.5e-05 1.6e-04 2.1e-04
7 Liver isoform ratio XM_017589708.3 0.04 0.03 2.7e-05 0.04 0.04 0.03 0.03 4.6e-05 3.6e-05 1.9e-04 1.8e-04
8 NAcc gene expression Pcgf5 0.08 0.06 1.8e-05 0.03 0.04 0.04 0.04 3.0e-05 9.3e-07 9.3e-07 3.8e-07
9 RMTg gene expression Pcgf5 0.36 0.15 2.9e-03 0.05 0.12 0.08 0.1 1.7e-02 4.4e-04 3.7e-03 1.3e-03
10 IC intron excision ratio chr1_243571612_243587315 0.14 0.08 2.4e-03 0.03 0.04 0.04 0.05 2.4e-02 1.0e-02 8.2e-03 4.4e-03
11 PL alternative polyA XM_017589708.3 0.03 0.02 2.6e-03 0.01 0.02 0.01 0.02 2.2e-02 1.6e-03 6.4e-02 4.2e-03
12 PL alternative polyA NM_001129882.1 0.03 0.02 1.3e-03 0.03 0.03 0.01 0.03 4.7e-04 7.6e-04 2.2e-02 6.1e-04
13 Liver gene expression Pcgf5 0.04 0.03 1.9e-04 0.02 0.02 0.01 0.01 5.2e-03 8.7e-04 3.6e-02 7.3e-03
14 PL isoform ratio NM_001129882.1 0.04 0.02 2.0e-04 0.02 0.04 0.03 0.03 1.9e-03 7.0e-05 5.4e-04 6.4e-04
15 Adipose mRNA stability Pcgf5 0.04 0.03 1.1e-03 0.01 0.01 0.01 0.01 1.2e-02 1.9e-02 4.1e-02 2.5e-02
16 NAcc isoform ratio NM_001129882.1 0.06 0.04 7.9e-07 0.05 0.04 0.05 0.05 2.6e-08 1.8e-07 4.1e-08 3.3e-08
17 NAcc alternative polyA NM_001129882.1 0.06 0.04 2.0e-06 0.05 0.04 0.04 0.05 5.0e-08 1.5e-06 1.2e-06 6.1e-08
18 NAcc alternative polyA XM_017589708.3 0.06 0.04 1.3e-06 0.05 0.04 0.04 0.05 1.7e-08 1.7e-06 2.2e-06 4.2e-08
19 pVTA alternative polyA NM_001129882.1 0.1 0.1 5.2e-04 0.04 0.03 0.06 0.03 2.7e-04 2.6e-03 8.7e-06 9.2e-04
20 pVTA alternative polyA XM_017589708.3 0.09 0.08 6.2e-04 0.04 0.03 0.06 0.04 2.3e-04 3.0e-03 7.5e-06 8.1e-04
21 pVTA isoform ratio NM_001129882.1 0.05 0.04 4.8e-03 0.04 0.01 0.05 0.02 5.2e-04 2.8e-02 4.7e-05 4.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density5.29.018.73.7-4.2-4.34.23.4-4.14.1-4.10.3-2.63.1-2.82.8-2.90.3-1.9-2.51.8-1.41.6-1.1
Area under the delay curve0.70.85.51.00.40.5-0.30.30.5-0.50.72.30.5-1.00.6-1.31.1-1.70.80.9-0.7-0.10.1-0.1
BMI with tail0.10.52.30.3-1.5-0.50.70.4-0.70.7-0.4-0.7-0.40.7-1.10.8-0.70.50.3-0.2-0.20.5-0.40.8
BMI without tail0.41.34.00.7-0.40.1-0.20.40.3-0.41.01.31.0-0.90.4-1.11.0-1.22.01.5-2.01.6-1.61.6
Body weight1.04.410.93.3-2.9-1.61.22.4-1.00.50.12.61.2-1.20.4-1.61.4-3.23.31.9-2.72.4-2.32.2
Weight adjusted by age0.50.71.60.4-0.8-0.90.90.4-0.91.0-1.2-0.2-0.71.0-1.10.9-1.00.2-1.2-1.21.2-0.30.30.1
Bone surface2.85.110.52.9-3.1-3.13.22.7-3.23.2-2.90.7-2.22.4-2.12.1-2.30.2-1.3-1.90.9-0.60.8-0.2
Bone volume3.46.014.63.5-3.8-3.83.63.3-3.53.4-3.30.9-2.02.3-1.82.0-2.1-0.3-1.1-1.60.9-0.40.5-0.1
Breakpoint value in progressive ratio session0.40.52.80.8-0.6-0.4-0.00.40.1-0.30.40.40.9-0.80.6-0.90.9-1.70.80.8-0.70.3-0.3-0.0
Number of licking bursts2.23.510.3-1.61.51.7-2.3-2.12.3-2.31.7-1.43.2-2.21.0-2.32.2-2.41.51.1-1.21.2-1.20.8
Context. condit. distance diff. score1.41.75.51.8-1.8-1.71.92.3-1.91.5-0.81.4-1.90.70.61.0-0.71.30.40.7-0.40.5-0.50.6
Locomotion velocity, session 11.31.45.4-2.31.11.6-1.5-2.21.4-1.00.7-2.20.90.0-1.10.0-0.10.4-0.8-0.90.90.1-0.00.2
Locomotion distance, session 10.10.20.7-0.80.60.5-0.4-0.60.4-0.30.2-0.80.10.0-0.40.1-0.10.2-0.3-0.20.6-0.00.10.0
Locomotion velocity, session 20.40.51.8-1.30.91.1-0.9-1.10.9-0.70.9-0.90.4-0.3-0.0-0.20.20.6-0.10.20.60.2-0.20.2
Locomotion distance, session 20.81.12.0-0.71.00.8-1.1-0.71.1-1.21.3-0.41.4-1.31.1-1.21.3-0.91.21.2-0.91.1-1.00.8
Locomotion velocity, session 30.20.20.70.4-0.3-0.20.20.5-0.20.00.10.40.1-0.30.6-0.30.4-0.40.50.9-0.50.8-0.80.8
Locomotion distance, session 30.80.82.70.8-0.4-0.30.31.0-0.2-0.20.51.00.2-0.81.6-0.60.8-0.60.91.6-0.91.3-1.31.2
Stereotopy head waving bouts, day 30.50.61.8-0.20.00.00.50.0-0.60.8-0.50.1-1.21.2-1.31.1-1.31.3-0.8-1.20.7-0.20.20.0
Stereotopy head waving duration, day 30.50.61.80.2-0.1-0.10.60.1-0.60.8-0.70.3-1.11.2-1.41.0-1.20.9-0.7-1.20.7-0.50.5-0.2
Locomotion velocity, session 70.50.62.31.4-0.8-0.90.81.4-0.70.4-0.11.5-0.5-0.21.0-0.10.2-0.30.40.9-0.1-0.10.1-0.1
Locomotion distance, session 70.40.62.21.5-0.9-1.00.91.4-0.80.5-0.41.4-0.4-0.00.9-0.00.1-0.50.30.8-0.1-0.30.2-0.2
Stereotopy head waving bouts, day 70.10.10.6-0.50.40.6-0.3-0.40.3-0.10.4-0.1-0.10.1-0.40.1-0.10.30.0-0.10.10.6-0.60.8
Stereotopy head waving duration, day 70.10.10.7-0.4-0.10.3-0.0-0.40.00.20.1-0.2-0.20.4-0.80.3-0.40.3-0.3-0.60.40.3-0.30.6
Locomotion velocity, session 80.20.30.60.2-0.6-0.50.40.3-0.50.4-0.6-0.3-0.60.5-0.10.5-0.40.6-0.5-0.50.7-0.80.8-0.7
Locomotion distance, session 80.40.61.80.7-0.5-0.80.91.3-0.90.5-0.00.7-1.1-0.01.20.4-0.11.10.71.2-0.40.5-0.50.4
Degree of sensitization distance0.10.20.90.4-0.1-0.20.10.1-0.00.0-0.20.6-0.10.1-0.1-0.1-0.0-0.20.1-0.20.0-0.90.8-0.9
Degree of sensitization stereotypy0.00.10.4-0.10.10.2-0.1-0.20.1-0.00.10.00.1-0.0-0.3-0.10.0-0.20.0-0.00.10.5-0.50.6
Conditioned locomotion0.30.31.40.7-1.0-1.20.80.8-0.80.6-0.9-0.5-0.10.3-0.10.4-0.3-0.1-0.3-0.10.40.0-0.00.0
Cocaine response after cond. corrected0.20.20.90.5-0.2-0.00.50.5-0.40.5-0.50.8-0.30.4-0.20.2-0.4-0.3-0.3-0.50.50.7-0.60.9
Cocaine response after cond. not corrected0.40.53.01.1-0.2-0.10.40.8-0.30.20.01.70.1-0.30.5-0.50.4-1.10.50.5-0.20.8-0.70.9
Cocaine response before conditioning1.21.44.10.60.50.7-0.80.10.9-1.11.61.90.8-1.41.3-1.61.5-1.41.52.0-1.3-0.10.0-0.3
Saline control response0.70.99.41.7-0.1-0.30.91.6-0.80.7-0.23.1-1.00.11.1-0.0-0.1-0.30.10.40.10.1-0.10.4
Bone: connectivity density3.85.910.22.2-2.8-2.93.02.0-3.03.2-3.1-0.4-2.32.9-2.72.6-2.80.8-2.1-2.41.9-2.02.1-1.6
Bone: cortical apparent density0.30.42.3-1.01.51.2-0.7-0.90.7-0.40.70.2-0.10.2-0.30.1-0.30.6-0.4-0.30.40.1-0.10.3
Bone: cortical area1.93.09.53.1-2.9-2.22.02.8-1.81.4-0.92.3-0.3-0.20.6-0.30.3-1.51.50.9-1.71.7-1.61.6
Bone: cortical porosity0.10.10.4-0.40.20.1-0.2-0.30.2-0.20.1-0.60.20.1-0.10.2-0.10.4-0.40.10.6-0.20.1-0.2
Bone: cortical porosity0.00.00.20.0-0.1-0.1-0.1-0.10.1-0.20.1-0.20.5-0.10.1-0.10.1-0.1-0.00.30.10.2-0.20.2
Bone: cortical thickness1.72.86.51.8-1.2-0.50.31.3-0.2-0.20.62.21.1-1.41.6-1.61.5-2.42.11.6-2.32.6-2.52.5
Bone: cortical thickness0.91.13.50.20.30.3-0.40.10.4-0.60.70.81.0-1.00.9-1.01.0-1.21.01.0-1.31.8-1.81.9
Bone: cortical tissue density0.30.52.4-1.11.61.2-0.7-1.00.7-0.40.70.1-0.10.2-0.40.2-0.30.7-0.5-0.40.50.1-0.10.3
Condit. Reinf. active minus inactive responses1.21.31.9-0.60.91.2-1.1-0.61.2-1.31.40.61.1-1.41.2-1.31.3-1.01.01.2-1.21.3-1.21.2
Condit. Reinf. active-inactive response ratio0.60.72.3-1.51.01.3-1.3-1.41.2-1.10.8-0.90.7-0.50.1-0.40.40.1-0.3-0.00.10.3-0.30.3
Condit. Reinf. active responses0.91.23.90.9-0.10.2-0.00.80.1-0.40.72.00.4-1.01.3-1.01.0-1.01.11.5-1.01.6-1.61.6
Condit. Reinf. inactive responses1.21.56.32.3-1.1-1.21.42.1-1.31.0-0.42.5-0.6-0.10.7-0.20.2-0.90.91.0-0.61.1-1.11.2
Incentive salience index mean2.32.84.5-0.20.91.4-1.4-0.41.4-1.71.91.41.6-2.11.9-2.02.0-1.71.91.9-2.12.0-2.01.8
Condit. Reinf. lever presses2.23.15.9-0.41.31.6-1.5-0.51.6-1.82.11.71.5-2.01.9-2.02.0-1.32.22.0-2.42.0-2.01.8
Condit. Reinf. active minus inactive responses0.81.02.51.2-0.4-0.50.51.3-0.50.10.51.60.0-0.71.5-0.60.7-0.81.41.3-1.11.4-1.31.3
Condit. Reinf. active-inactive response ratio0.30.30.80.50.1-0.30.30.6-0.20.00.40.7-0.1-0.40.9-0.30.4-0.30.90.7-0.60.8-0.80.8
Condit. Reinf. active responses1.11.54.82.2-1.2-1.31.42.1-1.31.0-0.32.2-0.5-0.21.0-0.20.2-1.00.90.9-0.81.2-1.11.3
Condit. Reinf. inactive responses0.60.83.01.7-1.3-0.91.01.5-0.90.8-0.61.6-0.2-0.00.2-0.20.1-1.10.20.2-0.30.7-0.60.8
Condit. Reinf. lever presses0.10.10.50.5-0.2-0.40.40.5-0.40.3-0.40.50.0-0.00.4-0.10.0-0.5-0.10.00.30.6-0.60.7
Condit. Reinf. lever reinforcers received0.81.13.71.8-0.9-1.01.11.8-1.00.7-0.11.9-0.3-0.31.0-0.30.3-0.90.90.8-0.81.2-1.11.3
Conditioned reinforcement - actives0.61.02.61.6-1.4-1.21.11.1-1.11.2-0.70.9-0.70.9-1.60.6-0.7-0.0-0.3-0.50.5-1.11.1-1.2
Conditioned reinforcement - inactives1.52.23.71.7-1.4-1.51.71.4-1.61.7-1.11.4-1.81.7-1.51.4-1.60.9-0.8-0.90.8-1.91.9-1.8
Conditioned locomotion1.41.83.90.9-1.4-1.11.30.7-1.31.5-1.1-0.1-1.51.7-2.01.5-1.61.1-1.0-1.21.2-1.81.8-1.5
Patch foraging indifference point 0 sec0.81.54.9-0.00.30.5-1.1-0.81.1-1.11.2-0.12.1-1.4-0.3-1.71.5-2.22.11.0-1.11.0-1.00.6
Patch foraging indifference point AUC1.42.09.00.41.21.7-1.0-0.21.2-1.11.93.00.6-1.21.2-1.61.3-1.62.11.6-1.70.5-0.50.8
Delay disc. indifference point, 0s delay0.80.94.91.6-0.7-0.50.41.2-0.30.00.22.20.2-0.71.1-0.90.8-1.51.01.2-1.00.4-0.30.3
Delay disc. indifference point, 16s delay0.40.43.41.3-0.2-0.40.50.8-0.40.5-0.31.8-0.3-0.0-0.2-0.40.1-1.0-0.00.10.1-0.40.4-0.4
Delay disc. indifference point, 2s delay0.20.21.30.60.3-0.10.30.3-0.30.4-0.41.1-0.40.3-0.40.1-0.3-0.3-0.6-0.40.6-0.40.5-0.1
Delay disc. indifference point, 24s delay2.02.38.20.51.21.3-1.1-0.21.3-1.31.92.91.0-1.71.7-2.01.8-1.71.81.9-1.90.4-0.50.4
Delay disc. indifference point, 4s delay0.90.95.21.30.00.1-0.10.70.2-0.30.62.30.5-1.00.8-1.31.1-1.91.11.2-1.00.2-0.20.3
Delay disc. indifference point, 8s delay1.11.33.0-0.21.51.5-1.3-0.91.4-1.21.31.61.1-1.30.5-1.61.3-1.70.60.7-0.6-0.0-0.00.0
Indifference point function ln k0.61.13.80.3-1.3-1.81.20.9-1.31.0-1.5-1.9-0.40.8-0.81.2-0.81.0-0.9-0.70.90.4-0.40.2
Indifference point function log k0.61.13.80.3-1.3-1.81.20.9-1.31.0-1.5-1.9-0.40.8-0.81.2-0.81.0-0.9-0.70.90.4-0.40.2
Patch foraging total patch changes 0 sec0.71.44.80.10.20.4-1.0-0.71.1-1.01.10.02.1-1.3-0.3-1.61.4-2.22.01.0-1.01.1-1.10.7
Patch foraging total patch changes 12 sec1.11.53.2-0.51.41.8-1.5-1.21.6-1.31.61.11.4-1.10.2-1.51.1-1.71.50.7-1.00.3-0.30.4
Patch foraging total patch changes 18 sec0.71.13.30.30.70.9-0.7-0.40.9-0.81.11.21.3-1.00.2-1.31.1-1.81.71.0-0.91.1-1.01.1
Patch foraging total patch changes 24 sec1.42.47.90.50.90.6-1.1-0.31.3-1.41.41.51.8-1.91.1-2.22.0-2.62.81.6-2.20.8-0.80.5
Patch foraging total patch changes 6 sec1.82.76.2-0.31.31.9-1.8-1.32.0-1.72.01.52.0-1.70.5-2.21.8-2.52.41.3-1.60.7-0.70.6
Patch foraging time to switch 0 sec0.51.05.5-1.91.00.8-1.2-1.71.1-1.00.3-2.31.1-0.40.0-0.30.40.0-0.9-0.70.4-0.20.2-0.3
Patch foraging water rate 0 sec0.20.51.20.9-0.6-0.50.71.1-0.70.6-0.11.1-0.70.20.10.3-0.30.50.80.6-0.71.0-1.01.1
Patch foraging water rate 12 sec0.10.31.20.6-1.1-0.50.10.3-0.1-0.0-0.2-0.30.7-0.4-0.0-0.40.5-1.10.50.30.00.6-0.50.5
Patch foraging water rate 18 sec0.20.21.10.9-1.0-1.00.50.8-0.50.3-0.20.1-0.1-0.10.1-0.10.2-0.10.60.30.1-0.20.2-0.6
Patch foraging water rate 24 sec0.91.24.12.0-1.7-1.01.01.8-0.90.6-0.32.0-0.2-0.40.8-0.50.5-0.91.50.8-0.61.0-0.90.8
Patch foraging water rate 6 sec0.10.20.5-0.0-0.2-0.20.40.1-0.40.5-0.6-0.5-0.40.5-0.40.6-0.50.60.4-0.70.50.1-0.10.1
Seeking ratio, delayed vs. immediate footshock0.10.21.1-0.40.10.4-0.3-0.10.2-0.40.4-0.40.1-0.30.5-0.10.20.41.00.5-0.5-0.30.3-0.5
Distance traveled before self-admin0.10.20.6-0.30.80.7-0.20.10.2-0.30.40.6-0.4-0.30.5-0.10.20.50.40.5-0.60.1-0.10.3
Distance traveled after self-admin2.63.26.00.7-0.7-0.91.70.8-1.72.0-2.00.2-2.32.5-1.92.3-2.41.6-2.0-2.31.9-1.91.9-1.3
Extensor digitorum longus weight0.51.86.02.0-1.2-1.20.92.0-0.80.30.32.4-0.5-0.72.3-0.60.8-0.61.92.0-1.90.1-0.2-0.0
Bone: elastic displacement2.02.37.3-2.71.91.2-1.0-2.10.8-0.40.2-2.7-0.50.9-1.31.2-1.12.3-1.8-1.21.8-1.01.0-0.9
Bone: elastic work1.92.58.6-2.01.30.5-0.1-1.3-0.00.4-0.5-2.2-1.41.6-1.81.9-1.82.9-2.0-1.62.1-1.31.3-1.2
Bone: endosteal estimation2.86.113.13.2-3.1-3.63.53.2-3.53.4-3.20.8-2.62.4-2.02.3-2.30.8-1.2-1.61.1-1.31.4-1.2
Bone: endosteal perimeter2.96.213.42.7-3.4-3.73.52.9-3.53.3-3.3-0.4-2.52.5-2.12.5-2.41.2-1.5-1.91.3-1.31.4-1.2
Epididymis fat weight0.62.15.62.1-2.4-2.12.22.2-2.12.0-1.80.8-1.21.2-1.01.2-1.20.10.7-0.70.10.4-0.30.5
Delta time in closed arm before/after self-admin2.22.14.3-1.50.61.4-1.7-1.51.7-1.81.6-1.22.1-1.51.0-1.41.5-1.01.21.1-1.31.5-1.51.4
Delta time in open arm before/after self-admin1.21.23.40.90.1-0.61.21.1-1.11.3-1.11.6-1.81.3-0.31.2-1.31.0-1.0-0.91.2-0.80.8-0.4
Diff in mean of infusions in LGA sessions0.10.20.70.0-0.7-0.60.40.3-0.40.2-0.1-0.9-0.40.00.20.3-0.10.60.20.4-0.30.4-0.40.1
Delay discount exponential model param0.91.05.5-0.9-0.5-0.60.5-0.2-0.60.6-0.8-2.4-0.71.1-0.71.5-1.21.8-0.9-1.00.80.0-0.0-0.0
Extinction: sum of active levers before priming0.50.51.30.3-0.70.1-0.30.20.4-0.60.70.40.7-1.10.8-1.01.1-0.70.91.1-1.00.7-0.70.5
Active lever presses in extinction session 60.60.62.41.6-1.0-1.31.21.5-1.21.0-0.70.8-0.50.40.20.4-0.3-0.5-0.30.10.00.1-0.10.0
Bone: final force0.61.03.51.9-1.6-1.51.21.6-1.10.8-0.71.00.0-0.10.1-0.20.2-1.21.00.3-1.10.7-0.70.6
Bone: final moment0.50.82.61.6-1.5-1.51.21.3-1.11.0-1.00.6-0.10.2-0.40.1-0.1-1.00.5-0.2-0.60.4-0.30.3
Food consumed during 24 hour testing period0.60.82.7-0.40.50.5-0.9-0.71.0-1.00.6-0.41.7-1.10.6-1.21.2-1.61.20.5-1.00.7-0.60.4
Glucose0.10.10.7-0.4-0.20.1-0.2-0.20.1-0.2-0.0-0.4-0.2-0.20.5-0.00.10.60.80.1-0.50.2-0.20.3
Heart weight0.10.21.1-0.3-0.30.1-0.2-0.60.20.1-0.2-0.3-0.10.6-1.00.3-0.5-0.10.3-0.80.0-0.50.5-0.0
Delay discount hyperbolic model param0.60.74.4-0.8-0.5-0.60.4-0.1-0.60.5-0.7-2.1-0.50.9-0.51.3-1.01.6-0.7-0.80.60.1-0.10.0
Intermittent access intake day 1-15 change0.30.73.10.7-1.8-1.40.90.5-0.90.9-0.6-0.9-0.30.8-1.60.7-0.70.20.1-0.40.2-0.50.5-0.5
Intermittent access intake escalation0.40.83.30.9-1.8-1.51.10.8-1.11.1-0.7-0.7-0.60.9-1.40.8-0.80.50.2-0.40.1-0.50.5-0.5
Intermittent access intake escalation 20.20.31.8-0.1-0.9-0.60.30.1-0.40.3-0.1-1.4-0.20.4-0.70.5-0.40.70.40.0-0.20.1-0.1-0.1
Intermitt. access day 1 inactive lever presses0.10.31.50.21.00.20.40.3-0.30.5-0.21.2-1.10.7-0.10.6-0.70.6-0.5-0.50.4-0.40.40.2
Intermitt. access day 15 inactive lever presses1.93.96.21.7-1.6-1.72.11.6-2.12.4-2.01.1-2.52.3-2.32.0-2.21.4-1.9-2.01.9-2.02.0-1.8
Intermitt. access escalation Index0.40.51.6-0.30.51.2-0.8-0.40.8-0.81.21.00.3-0.71.3-0.70.6-0.40.60.9-0.70.2-0.30.3
Intermittent access day 1 total infusions1.11.73.11.7-1.4-1.71.71.5-1.61.7-1.10.8-1.51.3-1.31.1-1.20.5-0.6-0.60.7-1.41.4-1.5
Intermittent access day 15 total infusions1.82.77.42.3-2.7-2.42.22.0-2.22.1-1.20.6-1.61.5-1.91.3-1.40.7-0.2-0.50.5-1.41.4-1.5
Intermittent access terminal intake (last 3 days)1.92.54.91.6-2.2-2.01.91.5-1.91.9-1.2-0.0-1.71.7-2.01.6-1.71.3-0.4-0.80.8-1.61.6-1.7
Intermittent access total infusions1.92.24.71.8-2.2-1.91.91.7-1.91.8-1.10.4-1.71.5-1.61.4-1.41.1-0.3-0.60.7-1.51.5-1.6
Intermittent access day 1 locomotion1.01.22.61.6-1.3-1.51.51.5-1.51.4-0.90.7-1.31.0-1.00.9-0.90.6-0.4-0.10.3-1.01.0-0.9
Intermittent access day 15 total locomotion1.73.15.51.2-2.1-2.02.11.4-2.12.2-1.8-0.8-1.92.1-2.32.1-2.01.6-1.1-1.41.4-1.41.4-1.2
Intermittent access total locomotion2.42.84.51.5-2.1-2.02.11.6-2.12.1-1.6-0.4-1.91.9-2.11.9-1.91.5-0.7-1.01.0-1.61.6-1.5
Intermittent access standard deviation0.30.72.71.2-1.6-1.31.21.1-1.11.1-0.70.2-0.70.7-0.90.6-0.70.4-0.3-0.40.4-0.30.3-0.3
Left kidney weight0.42.06.11.9-2.1-0.80.41.3-0.3-0.10.41.41.2-1.20.3-1.51.4-2.42.51.4-1.71.5-1.41.3
Right kidney weight0.83.612.11.3-1.30.1-0.70.30.8-1.21.41.32.5-2.20.8-2.52.4-3.33.52.2-2.71.7-1.71.3
Cocaine induced anxiety0.30.41.11.1-0.9-1.10.80.9-0.80.8-0.61.0-0.60.5-0.00.3-0.4-0.3-0.2-0.30.1-0.20.3-0.2
Post-drug Anxiety1.11.11.90.7-1.1-1.11.10.7-1.11.3-1.40.2-1.21.2-0.91.1-1.20.4-1.4-1.41.3-1.01.0-0.8
Baseline Anxiety0.91.02.6-0.3-0.4-0.50.7-0.0-0.70.9-1.3-1.3-0.81.1-1.11.2-1.11.0-1.6-1.41.6-0.80.8-0.6
Tail length1.35.116.43.1-0.7-0.80.42.1-0.2-0.30.84.01.6-2.01.9-2.42.2-3.63.42.4-3.12.5-2.41.9
Length with tail1.56.422.94.4-2.5-1.91.43.0-1.10.5-0.14.31.6-1.71.3-2.32.0-4.83.11.9-2.62.4-2.21.9
Length without tail1.23.715.43.9-3.6-2.92.43.1-2.21.8-1.72.1-0.10.10.0-0.30.1-2.71.00.2-0.41.0-0.90.9
Times rat made contact with spout0.40.42.31.10.0-0.50.40.9-0.30.10.21.50.2-0.30.6-0.50.4-1.00.70.7-0.80.5-0.50.5
Lifetime Intake1.92.44.31.7-2.1-1.91.81.5-1.81.8-1.20.2-1.61.5-1.71.4-1.50.9-0.5-0.70.8-1.91.8-2.0
Liver weight, left0.50.82.31.3-1.2-1.00.81.2-0.70.5-0.70.70.2-0.30.2-0.30.4-1.10.70.4-0.61.4-1.41.5
Liver weight, right0.81.44.32.1-2.1-1.71.71.8-1.61.5-1.11.1-0.80.8-0.90.5-0.6-0.60.6-0.2-0.10.6-0.50.8
Locomotor activity0.50.82.7-1.11.00.7-1.0-1.21.0-0.90.3-1.51.6-0.6-0.1-0.60.6-0.90.2-0.0-0.11.1-1.11.0
Locomotor testing distance0.71.34.2-1.61.31.3-1.5-1.81.5-1.30.9-1.62.1-0.7-0.3-0.80.8-1.10.1-0.1-0.00.9-0.90.7
Locomotor testing rearing0.10.30.90.1-0.20.0-0.10.10.1-0.20.3-0.40.8-0.40.3-0.40.5-0.60.30.6-0.70.9-0.90.8
Locomotion in novel chamber1.31.73.70.3-1.1-1.41.61.1-1.81.6-1.7-1.6-1.31.5-0.51.9-1.61.9-0.9-1.01.0-0.00.10.1
Locomotion in novel chamber post-restriction0.91.45.12.1-1.4-1.31.62.2-1.51.1-0.91.7-0.7-0.00.80.10.0-0.10.60.6-0.61.3-1.21.0
Fecal boli incidents, locomotor time 10.30.52.40.4-0.6-0.20.30.5-0.30.20.10.7-0.90.40.10.4-0.40.70.30.3-0.5-1.51.4-1.5
Change in fecal boli incidents, locomotor task0.70.71.2-0.31.00.6-0.8-0.60.9-0.90.90.11.1-0.90.6-1.01.0-1.10.60.7-0.50.8-0.80.8
Time >=10cm from walls, locomotor time 11.51.65.62.3-1.6-1.31.32.3-1.20.7-0.62.4-0.7-0.61.7-0.50.6-0.71.00.9-1.00.6-0.60.6
Bouts of movement, locomotor time 10.50.63.00.1-0.7-0.4-0.2-0.20.2-0.40.2-1.41.7-0.6-0.4-0.60.7-1.50.70.6-0.60.7-0.70.4
Total resting periods, locomotor time 10.50.53.30.6-0.8-0.5-0.00.10.1-0.20.1-0.81.6-0.5-0.4-0.70.7-1.80.70.6-0.50.5-0.50.3
Rest time, locomotor task time 10.20.31.3-0.50.20.1-0.4-0.80.4-0.10.0-1.10.60.4-1.00.2-0.3-0.3-0.4-0.50.5-0.60.6-0.4
Distance moved, locomotor task time 10.81.35.70.70.90.6-0.30.70.4-0.71.02.40.0-1.42.0-1.31.3-0.91.21.5-1.50.7-0.60.4
Vertical activity count, locomotor time 10.00.10.50.10.0-0.0-0.00.20.0-0.20.20.20.1-0.50.7-0.40.5-0.00.20.5-0.40.1-0.1-0.2
Time >=10cm from walls, locomotor time 20.81.28.01.5-0.10.10.11.10.0-0.30.62.8-0.0-1.01.7-1.21.1-1.21.51.3-1.50.1-0.10.1
Bouts of movement, locomotor time 20.71.12.5-1.01.21.1-1.5-1.31.5-1.41.6-0.31.1-1.00.3-1.11.1-0.81.00.9-0.9-0.40.3-0.5
Total resting periods, locomotor time 20.81.43.0-1.01.21.1-1.6-1.41.7-1.61.7-0.51.5-1.30.4-1.41.3-1.11.21.1-1.1-0.20.2-0.4
Rest time, locomotor task time 20.81.04.8-0.4-0.0-0.0-0.9-0.80.9-1.10.6-1.72.2-1.10.0-1.21.2-1.70.70.9-0.90.4-0.40.1
Distance moved, locomotor task time 20.80.98.11.00.50.40.41.2-0.30.20.52.8-1.1-0.41.6-0.30.30.30.71.0-1.00.7-0.60.8
Vertical activity count, locomotor time 20.20.31.9-0.20.70.7-0.3-0.20.4-0.20.71.4-0.8-0.00.4-0.1-0.10.6-0.00.2-0.2-0.80.8-0.8
Light reinforcement 10.30.92.60.4-0.7-1.20.90.3-0.91.0-1.3-1.2-0.31.1-1.60.9-1.0-0.2-0.6-1.20.6-0.80.9-0.8
Light reinforcement 20.81.23.6-1.91.40.9-0.9-1.90.8-0.40.0-1.8-0.00.8-1.40.7-0.80.8-0.8-1.61.1-1.01.0-0.8
Bone: marrow area3.16.714.13.3-3.2-3.83.73.3-3.73.5-3.40.8-2.72.6-2.22.5-2.50.9-1.2-1.71.2-1.41.5-1.2
Bone: maximum diameter4.88.922.44.1-4.7-4.64.54.4-4.44.1-3.71.2-3.12.6-1.72.6-2.50.9-0.9-1.30.7-0.20.30.0
Bone: maximum force1.11.95.72.4-2.3-2.32.12.2-2.01.8-1.50.9-0.80.9-0.70.7-0.7-0.50.3-0.2-0.50.3-0.20.3
Bone: maximum moment1.01.74.82.1-2.2-2.22.01.8-1.91.8-1.70.5-0.81.1-1.10.9-1.0-0.4-0.1-0.6-0.1-0.00.10.0
Mean time between licks in bursts0.41.04.2-2.01.41.5-1.4-1.91.4-1.11.0-1.40.7-0.3-0.1-0.20.20.8-0.3-0.3-0.00.2-0.30.3
Mean num. licks in bursts2.03.19.12.1-1.4-1.92.42.4-2.32.3-1.52.1-3.01.9-0.51.9-1.91.9-1.0-0.60.6-1.00.9-0.7
Cd content in liver1.01.13.8-1.91.11.7-1.6-1.91.6-1.31.3-1.21.0-0.6-0.2-0.60.50.2-0.00.4-0.10.1-0.10.0
Co content in liver0.80.92.5-1.20.91.0-0.3-1.00.30.1-0.1-0.5-1.01.0-0.91.0-1.11.6-1.4-1.41.2-0.90.9-0.6
Cu content in liver1.11.34.3-1.31.51.0-0.8-1.70.8-0.2-0.4-1.20.40.7-1.50.3-0.6-0.3-1.8-2.11.4-1.11.1-0.8
Fe content in liver1.01.23.1-1.31.81.3-1.5-1.51.5-1.41.2-0.61.3-1.10.6-1.11.1-0.80.70.4-1.00.3-0.20.1
K content in liver0.20.20.8-0.40.80.4-0.5-0.30.5-0.60.20.10.3-0.40.9-0.30.40.00.0-0.20.1-0.30.2-0.3
Mg content in liver0.20.21.1-0.61.00.6-0.5-0.50.5-0.40.10.10.1-0.10.3-0.10.10.1-0.3-0.50.10.1-0.10.2
Mn content in liver0.50.61.9-1.21.11.1-1.2-1.41.2-1.00.7-0.71.0-0.50.1-0.60.5-0.50.0-0.20.10.1-0.1-0.0
Na content in liver0.90.92.2-0.71.41.2-1.1-0.61.2-1.21.10.50.8-1.21.5-1.11.2-0.60.60.6-0.20.7-0.70.7
Rb content in liver0.10.10.70.4-0.0-0.50.30.4-0.30.2-0.4-0.10.3-0.20.3-0.20.2-0.60.4-0.2-0.80.3-0.20.2
Se content in liver12.314.534.9-5.65.85.7-5.7-5.95.7-5.14.5-2.34.1-3.11.4-3.23.0-1.51.10.8-1.30.9-1.00.8
Sr content in liver1.91.64.0-1.00.20.20.3-0.6-0.40.8-0.9-1.2-1.41.6-1.71.6-1.71.8-1.9-2.01.9-0.80.9-0.4
Zn content in liver3.63.910.1-2.73.23.1-2.9-2.62.9-2.72.6-0.41.8-1.81.6-1.71.7-0.20.80.9-1.10.6-0.70.5
Bone: minimum diameter2.34.213.43.5-3.7-3.33.13.4-3.02.6-2.21.5-1.61.2-0.51.1-1.0-0.10.4-0.1-0.60.2-0.10.1
Time in familiar zone, hab. session 10.20.20.80.1-0.2-0.30.3-0.0-0.30.4-0.5-0.5-0.00.6-0.50.5-0.6-0.1-0.9-0.60.7-0.30.3-0.1
Time in novel zone, hab. session 10.50.51.0-0.90.90.8-1.0-0.91.0-1.00.8-0.50.8-0.80.4-0.70.8-0.10.70.4-0.50.1-0.1-0.1
Total zone transitions, hab. session 10.10.10.50.2-0.1-0.40.30.2-0.30.3-0.5-0.4-0.00.3-0.40.3-0.3-0.3-0.5-0.50.70.3-0.20.5
Total locomotion distance, hab. session 10.30.51.3-0.91.10.5-0.7-0.70.7-0.70.4-0.90.9-0.50.4-0.40.5-0.5-0.30.40.40.9-0.91.1
Locomotion velocity, hab. session 10.40.61.8-0.91.30.7-0.8-0.70.8-0.90.7-0.60.7-0.70.6-0.50.7-0.40.10.7-0.00.9-0.91.0
Time in familiar zone, hab. session 20.20.20.7-0.70.50.5-0.5-0.80.5-0.3-0.1-0.60.30.2-0.40.1-0.20.2-0.4-0.70.4-0.20.2-0.2
Time in novel zone, hab. session 20.10.10.20.1-0.3-0.20.20.2-0.20.2-0.00.0-0.40.2-0.10.2-0.20.3-0.10.0-0.0-0.30.3-0.2
Total zone transitions, hab. session 20.50.61.4-0.70.70.8-0.8-0.80.9-0.80.6-0.41.1-0.70.2-0.80.7-1.10.40.3-0.21.1-1.01.2
Total locomotion distance, hab. session 20.71.01.8-1.31.01.0-1.2-1.21.1-1.10.8-1.31.2-0.90.4-0.70.8-0.60.30.5-0.11.2-1.21.2
Locomotion velocity, hab. session 20.81.12.0-1.21.01.0-1.2-1.11.2-1.20.9-1.21.4-1.10.7-0.91.0-0.80.50.8-0.41.3-1.31.3
Novel to familiar place preference ratio0.60.61.41.1-0.9-1.21.00.9-1.01.0-0.80.1-0.60.7-1.00.6-0.6-0.3-0.2-0.3-0.0-0.90.9-0.9
Novelty place preference0.70.81.61.0-0.9-1.31.10.9-1.11.1-1.0-0.1-0.70.9-1.10.8-0.8-0.1-0.4-0.50.1-1.01.1-1.1
Time in novel zone, NPP test0.50.51.50.6-0.7-1.10.70.4-0.70.7-0.8-0.7-0.20.7-1.00.5-0.6-0.2-0.3-0.50.1-1.11.1-1.2
Total zone transitions, NPP test0.91.32.4-0.71.11.0-1.3-0.81.3-1.41.0-0.01.6-1.41.2-1.41.4-1.30.80.9-0.31.2-1.21.1
Total locomotion distance, NPP test0.91.23.2-1.21.81.3-1.3-1.01.3-1.31.0-0.11.1-1.21.1-1.01.1-0.50.80.7-0.61.3-1.31.3
Locomotion velocity, NPP test0.91.32.7-0.71.71.2-1.1-0.61.1-1.21.10.61.0-1.21.3-1.11.2-0.71.11.0-0.91.6-1.51.5
Intraocular pressure0.10.20.80.4-0.2-0.90.50.3-0.50.5-0.7-0.70.20.2-0.50.2-0.2-0.50.8-0.20.0-0.20.3-0.4
Delta distance traveled before/after self-admin3.43.65.91.5-2.1-1.92.21.5-2.22.4-2.30.2-2.22.4-2.02.2-2.31.3-1.7-2.01.8-1.61.6-1.3
Delta ambulatory time before/after self-admin3.84.77.92.1-2.3-2.22.62.0-2.62.8-2.41.0-2.72.7-2.02.4-2.61.4-1.8-2.11.8-1.81.8-1.4
Parametrial fat weight2.25.110.90.10.81.3-1.8-0.51.9-2.32.61.52.7-2.82.3-2.92.9-2.92.82.8-3.32.1-2.21.9
Pavlov. Cond. lever latency1.62.14.8-0.3-0.6-0.80.7-0.4-0.81.2-1.5-1.9-0.81.7-2.21.6-1.71.0-2.0-2.22.0-1.51.5-1.2
Pavlov. Cond. magazine entry latency2.02.54.1-0.90.81.5-1.6-0.91.7-1.92.00.51.5-2.01.8-1.91.9-0.91.81.9-1.71.7-1.81.4
Pavlov. Cond. change in total contacts2.62.74.7-1.01.31.8-1.7-1.01.8-1.92.20.71.6-1.91.6-1.81.8-1.21.61.9-1.71.9-1.91.7
Pavlov. Cond. index score2.83.66.8-0.10.61.2-1.4-0.21.4-1.92.11.41.7-2.42.5-2.32.4-1.52.52.6-2.52.2-2.21.8
Pavlov. Cond. latency score3.03.87.60.20.51.1-1.20.21.2-1.72.01.91.5-2.42.7-2.32.4-1.62.72.7-2.62.3-2.31.9
Pavlov. Cond. lever contacts2.22.65.1-0.00.91.2-1.2-0.11.2-1.51.91.71.2-2.02.2-1.91.9-1.32.22.3-2.21.7-1.71.3
Pavlov. Cond. magazine entry number1.31.62.61.0-0.4-1.21.40.9-1.41.6-1.50.2-1.51.6-1.21.5-1.60.6-1.3-1.41.3-1.31.4-1.0
Pavlov. Cond. intertrial magazine entries0.40.52.11.5-0.5-0.80.91.3-0.80.7-0.41.4-0.20.00.2-0.10.1-0.80.30.4-0.30.5-0.50.6
Pavlov. Cond. lever-magazine prob. diff.3.03.86.7-0.40.91.5-1.6-0.51.7-2.12.31.21.8-2.52.4-2.32.4-1.52.42.6-2.42.1-2.11.7
Pavlov. Cond. response bias1.82.23.6-1.31.01.6-1.8-1.31.8-1.91.8-0.11.7-1.81.4-1.71.7-0.81.41.5-1.51.4-1.41.0
Pavlov. Cond. lever latency0.10.10.7-0.3-0.1-0.3-0.2-0.10.1-0.30.3-0.80.2-0.20.3-0.10.20.20.60.5-0.6-0.30.2-0.5
Pavlov. Cond. magazine entry latency1.01.21.9-0.91.01.4-1.3-1.01.4-1.41.30.11.2-1.21.2-1.21.2-0.90.61.0-0.61.0-1.01.1
Pavlov. Cond. change in total contacts0.30.53.50.60.30.4-0.10.50.2-0.20.51.90.0-0.61.1-0.70.6-0.60.50.8-0.20.7-0.70.8
Pavlov. Cond. index score0.30.51.70.40.20.5-0.20.20.3-0.40.41.30.4-0.70.8-0.80.7-0.90.40.7-0.31.0-0.91.1
Pavlov. Cond. latency score0.30.31.40.50.00.3-0.00.40.1-0.10.21.20.2-0.50.7-0.60.5-0.80.30.6-0.10.9-0.91.1
Pavlov. Cond. lever contacts0.10.10.70.20.00.30.10.1-0.10.2-0.30.8-0.30.2-0.10.1-0.2-0.1-0.5-0.40.50.3-0.20.5
Pavlov. Cond. magazine entry number1.41.72.60.8-1.3-1.61.50.9-1.51.6-1.6-0.7-1.31.5-1.61.5-1.51.1-0.9-1.40.8-1.31.3-1.3
Pavlov. Cond. intertrial magazine entries0.50.82.61.6-1.0-1.30.91.4-0.80.5-0.40.90.2-0.40.6-0.50.5-1.31.20.7-1.30.5-0.40.3
Pavlov. Cond. lever-magazine prob. diff.0.40.61.40.30.30.6-0.40.10.4-0.50.51.20.5-0.80.9-0.90.8-1.00.50.8-0.31.1-1.11.2
Pavlov. Cond. response bias0.30.41.1-0.30.71.0-0.7-0.50.8-0.70.70.90.5-0.60.6-0.70.6-0.70.10.4-0.00.6-0.60.8
Time in closed arm before self-admin0.10.10.6-0.20.60.1-0.2-0.30.2-0.10.1-0.30.10.2-0.10.1-0.10.1-0.2-0.20.3-0.70.7-0.8
Time in closed arm after self-admin1.41.52.5-1.11.51.5-1.5-1.21.5-1.61.3-0.01.6-1.31.4-1.31.3-0.90.80.9-0.91.0-1.00.8
Time in open arm before self-admin0.20.21.6-0.8-0.00.3-0.2-0.60.2-0.1-0.2-1.30.10.2-1.00.3-0.20.4-0.2-0.40.00.2-0.20.3
Time in open arm after self-admin1.51.63.00.6-0.9-1.11.30.7-1.41.6-1.7-0.5-1.31.6-1.71.4-1.50.6-1.5-1.61.7-0.91.0-0.6
Bone: periosteal estimation2.85.915.13.8-3.9-3.93.73.7-3.63.3-3.01.5-2.11.9-1.41.7-1.7-0.1-0.3-0.90.0-0.20.3-0.1
Bone: periosteal perimeter2.23.710.83.1-3.3-3.22.93.2-2.92.5-2.21.2-1.51.2-0.61.2-1.1-0.10.0-0.3-0.20.1-0.10.2
Bone: post-yield work1.21.86.32.5-2.0-1.61.31.8-1.10.9-0.41.80.4-0.30.1-0.60.5-2.21.40.9-1.71.1-1.01.0
Progressive ratio test 1 active lever presses2.93.65.61.6-1.8-2.12.21.6-2.22.4-2.10.3-2.32.1-2.12.0-2.11.6-1.6-1.71.7-1.81.8-1.9
Progressive ratio test 1 breakpoint2.63.15.01.6-1.7-1.92.11.6-2.12.2-1.90.4-2.12.0-1.91.9-2.01.4-1.4-1.51.6-1.61.6-1.7
Progressive ratio test 1 inactive lever presses1.42.13.91.7-1.5-1.51.51.2-1.51.7-0.90.8-1.51.6-2.01.2-1.50.3-0.7-0.80.8-2.01.9-2.0
Progressive ratio test 2 active lever presses4.24.98.42.4-2.8-2.72.92.3-2.92.9-2.30.3-2.42.3-2.82.2-2.31.4-1.1-1.51.4-1.81.9-1.8
Progressive ratio test 2 breakpoint4.75.49.12.5-2.9-2.83.02.4-3.03.0-2.40.3-2.62.5-2.92.3-2.41.5-1.2-1.61.5-1.92.0-1.9
Progressive ratio test 2 inactive lever presses2.43.97.21.5-1.9-1.92.11.4-2.12.3-1.80.0-2.32.3-2.72.1-2.31.7-1.5-1.81.7-2.22.2-2.2
Incentive Sensitization - Responses1.72.55.72.1-2.4-2.22.11.8-2.12.0-1.20.3-1.51.5-2.31.3-1.40.3-0.1-0.50.4-1.21.3-1.2
Incentive Sensitization - Breakpoint2.12.76.42.3-2.5-2.32.21.9-2.22.1-1.30.4-1.61.6-2.31.4-1.50.3-0.3-0.60.5-1.31.4-1.3
Sum of active levers in priming session hrs 5-60.50.51.5-0.80.90.6-0.6-1.10.6-0.30.3-0.40.30.4-0.30.1-0.3-0.4-1.2-0.81.0-0.90.8-0.6
Progressive ratio0.60.92.70.0-0.10.8-0.50.10.5-0.91.00.11.0-1.31.5-1.11.3-0.71.71.5-1.50.6-0.60.3
Food seeking constrained by brief footshock0.40.52.10.6-1.4-1.00.30.7-0.3-0.1-0.2-0.80.7-0.90.6-0.70.9-0.61.10.9-1.00.2-0.2-0.3
Seeking ratio, punishment vs. effort0.00.10.3-0.00.1-0.5-0.1-0.20.1-0.1-0.3-0.20.2-0.2-0.4-0.30.2-0.4-0.2-0.30.2-0.00.1-0.2
Retroperitoneal fat weight0.10.51.30.9-0.7-0.40.50.8-0.50.4-0.20.70.2-0.00.1-0.10.1-0.71.00.3-1.01.1-1.11.1
Reaction time number correct0.81.63.91.6-1.7-2.01.71.6-1.71.6-2.00.4-1.11.1-0.31.1-1.10.4-1.3-1.00.8-0.80.7-0.8
Reaction time mean minus median0.20.42.1-0.8-0.60.30.0-0.6-0.10.3-0.2-1.4-0.20.6-1.20.7-0.71.0-0.3-0.80.8-0.20.3-0.4
Reaction time mean minus median AUC0.20.51.3-0.90.00.6-0.1-0.70.00.2-0.2-1.1-0.30.6-1.10.7-0.71.0-0.2-1.11.0-0.50.5-0.5
Reaction time num false alarms0.50.72.01.4-0.5-1.00.61.3-0.60.20.11.10.2-0.70.9-0.60.7-1.11.11.4-0.90.6-0.60.8
Reaction time num false alarms AUC0.60.92.50.9-0.2-0.60.10.8-0.0-0.30.50.80.9-1.11.1-1.11.1-1.41.51.6-1.00.8-0.80.8
Reaction time trials correct on left0.81.63.91.6-1.7-2.01.71.6-1.71.6-2.00.4-1.11.1-0.31.1-1.10.4-1.3-1.00.8-0.80.7-0.8
Reaction time trials on left0.81.53.81.6-1.6-1.91.71.6-1.61.6-1.90.5-1.11.1-0.31.0-1.00.4-1.3-0.90.7-0.70.7-0.7
Reaction time mean1.11.86.9-2.61.72.3-1.9-2.31.8-1.51.3-1.81.0-0.6-0.1-0.50.50.80.1-0.10.20.2-0.20.3
Reaction time mean AUC1.32.18.5-2.92.02.5-2.1-2.62.0-1.71.4-2.00.9-0.6-0.1-0.40.41.00.0-0.10.2-0.00.00.0
Median of all reaction times1.52.28.5-2.92.22.4-2.1-2.52.0-1.81.3-1.91.1-0.70.1-0.50.60.9-0.1-0.10.20.1-0.10.3
Reaction time omissions0.20.31.8-0.40.30.9-0.2-0.10.2-0.20.50.5-0.1-0.40.4-0.20.20.30.10.3-0.21.3-1.21.4
Reaction time false alarm rate0.71.03.00.30.40.1-0.40.20.4-0.71.10.51.1-1.21.0-1.21.3-1.41.71.7-1.11.0-1.01.1
Reaction time premature initiation rate0.30.42.21.2-1.5-0.80.60.9-0.60.4-0.40.30.3-0.20.1-0.30.3-0.90.50.40.1-0.20.2-0.3
Reaction time premature initiations0.81.56.62.2-2.6-2.11.71.9-1.61.3-1.60.6-0.30.4-0.10.3-0.3-0.8-0.2-0.10.4-0.60.6-0.7
Std. dev. reaction times0.30.62.3-1.50.51.4-0.9-1.30.8-0.60.6-1.20.4-0.1-0.7-0.0-0.00.60.2-0.40.50.3-0.20.2
Reaction time trials completed0.81.53.81.6-1.6-1.91.71.6-1.61.6-1.90.5-1.11.1-0.31.0-1.00.4-1.3-0.90.7-0.70.7-0.7
Reaction time trials AUC0.61.23.01.4-1.4-1.71.41.4-1.41.3-1.70.5-0.90.9-0.10.9-0.80.3-1.2-0.70.6-0.60.5-0.6
Run reversals in cocaine runway, females0.40.41.7-0.70.0-0.10.1-0.5-0.10.3-0.6-1.3-0.00.8-1.10.8-0.80.7-1.1-1.00.9-0.20.2-0.3
Run reversals in cocaine runway, males0.80.82.1-0.50.40.7-0.9-0.71.0-1.01.0-0.41.4-1.20.6-1.21.2-1.20.60.9-1.00.9-0.80.3
Latency to leave start box in cocaine runway0.91.02.81.1-0.4-0.61.41.7-1.41.2-0.71.0-1.60.50.20.9-0.61.20.20.3-0.31.2-1.11.1
Latency to leave start box in cocaine runway, F0.50.61.50.70.2-0.30.81.2-0.80.50.21.0-1.00.10.50.3-0.20.80.80.8-0.91.2-1.21.1
Latency to leave start box in cocaine runway, M0.70.61.70.8-1.0-0.81.11.1-1.11.1-1.30.1-0.90.6-0.30.7-0.60.6-0.5-0.50.60.5-0.40.5
Std. dev. time between licks in bursts1.21.75.6-2.41.71.8-2.0-2.31.9-1.71.3-1.71.3-0.7-0.0-0.70.70.2-0.1-0.10.1-0.10.0-0.2
Total sessions with >9 infusions0.20.31.40.6-0.4-0.00.0-0.00.00.10.40.7-0.00.1-1.1-0.2-0.0-0.40.20.1-0.2-1.00.9-1.2
Short access day 1 total inactive lever presses1.72.34.61.0-1.0-1.21.60.9-1.61.9-1.5-0.1-1.72.1-2.11.9-2.00.9-1.5-1.61.5-1.51.5-1.1
Short access day 10 total inactive lever presses0.30.76.00.90.70.8-0.20.40.3-0.30.72.40.3-0.40.7-0.80.5-1.40.50.7-0.80.5-0.50.7
Short access day 1 total infusions0.20.31.50.40.10.2-0.0-0.20.10.20.20.5-0.20.3-0.8-0.0-0.2-0.2-0.0-0.20.2-1.11.1-1.2
Short access day 10 total infusions0.50.64.0-0.1-0.0-0.2-0.1-0.40.10.20.3-0.2-0.50.7-1.10.4-0.60.6-0.3-0.30.4-1.81.7-2.0
Short access total infusions1.01.34.41.0-1.1-1.10.90.6-0.91.1-0.60.1-1.01.1-1.50.8-1.00.4-0.6-0.70.7-1.91.9-2.1
Short access day 1 locomotion0.10.11.1-0.00.20.6-0.2-0.30.2-0.00.70.3-0.20.1-1.00.0-0.10.60.30.4-0.4-0.20.2-0.3
Short access day 10 total locomotion0.10.10.5-0.60.30.1-0.2-0.30.1-0.10.4-0.70.00.1-0.10.2-0.10.7-0.10.2-0.30.2-0.2-0.0
Short access total locomotion0.20.21.2-0.70.50.5-0.4-0.70.4-0.20.6-0.6-0.00.3-1.10.2-0.30.6-0.10.1-0.1-0.40.3-0.4
One hour access (0.3 mA shock)4.04.611.02.7-3.3-2.92.92.4-2.82.8-2.20.3-2.32.1-2.61.9-2.01.1-0.9-1.31.3-1.51.5-1.5
Compulsive drug intake0.30.42.81.2-0.5-0.30.51.0-0.50.3-0.21.7-0.4-0.10.3-0.20.2-0.40.70.5-0.40.5-0.50.7
One hour access (shock baseline)1.42.15.71.2-2.4-2.01.61.0-1.61.6-1.4-1.1-0.91.3-1.91.2-1.30.6-0.8-1.11.0-1.71.7-1.9
Social response proportion1.71.93.9-0.6-0.6-0.80.9-0.1-1.01.2-1.5-2.0-1.11.7-1.51.9-1.81.9-1.8-1.81.6-1.31.2-1.0
Social responses1.41.73.90.3-1.2-1.11.10.3-1.11.4-1.5-1.2-0.91.7-2.01.6-1.61.1-1.3-1.51.2-1.51.5-1.3
Social time0.60.81.6-0.80.91.3-1.2-1.11.2-1.11.2-0.21.0-0.90.4-1.00.9-0.70.90.6-1.0-0.10.1-0.3
Soleus weight1.13.25.51.3-2.1-1.92.21.6-2.22.3-2.3-0.1-2.32.2-1.62.2-2.21.6-1.4-1.81.1-1.01.0-0.6
Bone: stiffness1.32.17.62.8-2.4-2.11.62.4-1.51.0-0.71.8-0.0-0.30.8-0.40.4-1.51.71.2-1.90.6-0.50.4
Tibialis anterior weight0.62.08.62.5-1.3-1.51.42.6-1.30.8-0.02.9-1.1-0.32.1-0.10.3-0.11.31.8-1.3-0.1-0.0-0.1
Time to tail flick, vehicle, before self-admin1.01.12.1-1.00.30.4-0.0-0.8-0.10.4-0.4-1.2-0.81.1-1.31.1-1.21.4-1.1-1.21.3-1.51.4-1.4
Time to tail flick, vehicle, after self-admin1.82.46.31.0-0.10.1-0.60.60.7-1.11.61.41.7-1.91.9-1.92.0-2.12.22.5-2.11.3-1.31.0
Time to tail flick, test, before self-admin0.90.92.01.1-1.4-1.31.41.3-1.41.3-1.10.5-1.31.0-0.21.1-1.01.1-0.3-0.30.20.2-0.20.2
Time to tail flick, test, after self-admin0.30.32.2-0.11.20.7-0.5-0.30.5-0.40.71.5-0.1-0.20.4-0.30.2-0.00.40.3-0.30.1-0.10.1
Delta time to tail flick, vehicle, before/after SA3.93.77.62.4-0.8-0.90.32.0-0.2-0.50.92.41.5-2.12.6-2.12.2-2.72.52.7-2.62.0-1.91.6
Delta time to tail flick, test, before/after SA0.40.41.2-0.41.10.9-0.9-0.70.9-0.80.90.60.6-0.60.3-0.80.7-0.70.60.5-0.5-0.10.1-0.0
Tibia length0.20.52.80.8-0.3-0.40.10.5-0.0-0.0-0.20.51.0-0.60.4-0.80.7-1.70.70.0-0.81.1-1.01.0
Ambulatory time before self-admin0.20.31.0-0.91.01.0-0.6-0.50.6-0.70.8-0.0-0.0-0.40.5-0.20.30.60.50.6-0.60.3-0.30.5
Ambulatory time after self-admin2.63.06.40.9-1.1-1.21.91.2-1.92.1-1.80.3-2.52.4-1.82.3-2.41.9-1.5-1.71.4-1.51.5-1.0
Bone: tissue strength0.30.31.1-0.80.20.5-0.6-1.00.6-0.40.0-0.80.30.2-0.60.0-0.10.0-0.4-0.70.3-0.80.8-0.8
Total heroin consumption0.40.51.91.4-1.1-1.10.70.9-0.70.6-0.40.60.10.3-0.3-0.0-0.1-1.4-0.30.00.1-0.40.4-0.3
Bone: trabecular number3.35.510.72.7-3.3-3.23.12.3-3.03.2-3.2-0.2-1.72.5-2.42.2-2.4-0.0-1.8-2.21.7-1.41.5-1.1
Bone: trabecular spacing2.23.05.0-0.91.72.0-1.9-1.02.0-2.12.21.31.6-2.12.2-2.12.1-1.31.51.8-1.21.5-1.51.4
Bone: trabecular thickness2.43.07.72.1-2.8-2.72.31.9-2.32.2-2.3-0.3-1.11.6-1.81.4-1.5-0.3-0.9-1.20.8-1.11.2-1.1
Bone: trabecular tissue density1.32.04.51.9-1.4-1.82.12.1-2.12.0-1.21.1-2.01.4-0.71.5-1.41.0-0.4-0.30.4-0.30.3-0.1
Water consumed over 24 hours0.71.03.00.80.4-0.2-0.30.40.4-0.70.71.21.1-1.11.7-1.21.2-1.61.31.4-1.40.6-0.60.3
Number of responses in last shaping day0.60.74.30.2-0.30.10.4-0.1-0.40.7-0.30.0-0.71.0-2.10.8-1.00.5-1.1-0.81.0-1.01.0-0.7