Hub : Genes

Pcgf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg mRNA stability Pcgf5 0.15 0.09 5.9e-03 0.03 0.09 0.05 0.04 5.0e-02 3.0e-03 2.2e-02 3.2e-02
2 Liver isoform ratio NM_001129882.1 0.05 0.03 2.3e-05 0.03 0.03 0.02 0.03 1.3e-04 5.4e-04 1.0e-03 6.9e-04
3 PL gene expression Pcgf5 0.07 0.04 5.0e-07 0.07 0.06 0.06 0.06 4.4e-08 3.5e-07 9.0e-07 2.3e-07
4 Liver alternative polyA XM_017589708.3 0.05 0.03 1.9e-06 0.04 0.04 0.03 0.03 4.8e-05 2.2e-05 1.4e-04 1.3e-04
5 Brain mRNA stability Pcgf5 0.03 0.02 5.4e-03 0 0.02 0 0.01 3.2e-01 6.1e-03 1.3e-01 8.1e-02
6 Liver alternative polyA NM_001129882.1 0.05 0.03 2.9e-06 0.04 0.04 0.03 0.03 7.1e-05 3.5e-05 1.6e-04 2.1e-04
7 IC intron excision ratio chr1_243577130_243587315 0.1 0.08 9.8e-03 0.05 0.01 0.01 0.02 3.5e-03 9.9e-02 9.9e-02 4.4e-02
8 Liver isoform ratio XM_017589708.3 0.04 0.03 2.7e-05 0.04 0.04 0.03 0.03 4.6e-05 3.6e-05 1.9e-04 1.7e-04
9 NAcc gene expression Pcgf5 0.08 0.06 1.8e-05 0.03 0.04 0.04 0.04 3.0e-05 9.3e-07 9.3e-07 4.0e-07
10 RMTg gene expression Pcgf5 0.36 0.15 2.9e-03 0.05 0.12 0.08 0.1 1.7e-02 4.4e-04 3.7e-03 1.4e-03
11 IC intron excision ratio chr1_243571612_243587315 0.14 0.08 2.4e-03 0.03 0.04 0.04 0.05 2.4e-02 1.0e-02 8.2e-03 4.8e-03
12 PL alternative polyA XM_017589708.3 0.03 0.02 2.6e-03 0.01 0.02 0.01 0.02 2.2e-02 1.6e-03 6.4e-02 4.4e-03
13 PL alternative polyA NM_001129882.1 0.03 0.02 1.3e-03 0.03 0.03 0.01 0.03 4.7e-04 7.6e-04 2.2e-02 6.7e-04
14 Liver gene expression Pcgf5 0.04 0.03 1.9e-04 0.02 0.02 0.01 0.01 5.2e-03 8.7e-04 3.9e-02 7.2e-03
15 PL isoform ratio NM_001129882.1 0.04 0.02 2.0e-04 0.02 0.04 0.03 0.03 1.9e-03 7.0e-05 5.4e-04 6.0e-04
16 Adipose mRNA stability Pcgf5 0.04 0.03 1.1e-03 0.01 0.01 0.01 0.01 1.2e-02 1.9e-02 4.1e-02 2.4e-02
17 NAcc isoform ratio NM_001129882.1 0.06 0.04 7.9e-07 0.05 0.04 0.05 0.05 2.6e-08 1.8e-07 4.1e-08 3.4e-08
18 NAcc alternative polyA NM_001129882.1 0.06 0.04 2.0e-06 0.05 0.04 0.04 0.05 5.0e-08 1.5e-06 1.2e-06 5.8e-08
19 NAcc alternative polyA XM_017589708.3 0.06 0.04 1.3e-06 0.05 0.04 0.04 0.05 1.7e-08 1.7e-06 2.2e-06 4.0e-08
20 pVTA alternative polyA NM_001129882.1 0.1 0.1 5.2e-04 0.04 0.03 0.06 0.03 2.7e-04 2.6e-03 8.7e-06 9.6e-04
21 pVTA alternative polyA XM_017589708.3 0.09 0.08 6.2e-04 0.04 0.03 0.06 0.03 2.3e-04 3.0e-03 7.4e-06 8.5e-04
22 pVTA isoform ratio NM_001129882.1 0.05 0.04 4.8e-03 0.04 0.01 0.05 0.02 5.2e-04 2.8e-02 5.8e-05 4.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density5.19.418.73.74.24.34.23.4-4.1-4.04.1-4.10.3-2.63.12.82.8-2.9-0.31.92.5-1.81.5-1.61.2
Area under the delay curve0.50.85.51.0-0.4-0.5-0.30.30.5-0.9-0.50.72.30.5-1.0-0.6-1.31.11.7-0.8-0.90.70.1-0.20.0
BMI with tail0.10.42.30.31.50.50.70.4-0.7-0.10.7-0.4-0.7-0.40.71.10.8-0.7-0.5-0.30.20.2-0.50.5-0.8
BMI without tail0.21.34.00.70.4-0.1-0.20.40.30.4-0.41.01.31.0-0.9-0.4-1.11.01.2-2.0-1.52.0-1.71.6-1.6
Body weight1.04.310.93.32.91.61.22.4-1.0-1.40.50.12.61.2-1.2-0.4-1.61.43.2-3.3-1.92.7-2.42.2-2.2
Weight adjusted by age0.20.71.60.40.80.90.90.4-0.9-0.81.0-1.2-0.2-0.71.01.10.9-1.0-0.21.21.2-1.20.3-0.3-0.1
Bone surface2.85.411.92.93.13.13.22.7-3.2-3.43.2-2.90.7-2.22.42.12.1-2.3-0.21.31.9-0.90.7-0.80.3
Bone volume3.26.414.63.53.83.83.63.3-3.5-3.63.4-3.30.9-2.02.31.82.0-2.10.31.11.6-0.90.4-0.60.1
Breakpoint value in progressive ratio session0.30.52.80.80.60.4-0.00.40.1-0.4-0.30.40.40.9-0.8-0.6-0.90.91.7-0.8-0.80.7-0.30.3-0.0
Number of licking bursts1.23.610.2-1.6-1.5-1.7-2.3-2.12.32.5-2.31.7-1.43.2-2.2-1.0-2.32.22.4-1.5-1.11.2-1.21.2-0.9
Context. condit. distance diff. score1.51.85.51.81.81.71.92.3-1.9-1.91.5-0.81.4-1.90.7-0.61.0-0.7-1.3-0.4-0.70.4-0.50.5-0.6
Locomotion velocity, session 11.31.45.4-2.3-1.1-1.6-1.5-2.21.41.6-1.00.7-2.20.90.01.10.0-0.1-0.40.80.9-0.9-0.00.1-0.1
Locomotion distance, session 10.10.20.7-0.8-0.6-0.5-0.4-0.60.40.0-0.30.2-0.80.10.00.40.1-0.1-0.20.30.2-0.60.1-0.1-0.0
Locomotion velocity, session 20.40.51.8-1.3-0.9-1.1-0.9-1.10.91.2-0.70.9-0.90.4-0.30.0-0.20.2-0.60.1-0.2-0.6-0.20.2-0.2
Locomotion distance, session 20.81.12.0-0.7-1.0-0.8-1.1-0.71.11.1-1.21.3-0.41.4-1.3-1.1-1.21.30.9-1.2-1.20.9-1.11.0-0.8
Locomotion velocity, session 30.20.20.70.40.30.20.20.5-0.2-0.30.00.10.40.1-0.3-0.6-0.30.40.4-0.5-0.90.5-0.80.8-0.8
Locomotion distance, session 30.70.82.70.80.40.30.31.0-0.2-0.5-0.20.51.00.2-0.8-1.6-0.60.80.6-0.9-1.60.9-1.31.3-1.3
Stereotopy head waving bouts, day 30.50.61.8-0.2-0.0-0.00.50.0-0.6-0.40.8-0.50.1-1.21.21.31.1-1.3-1.30.81.2-0.70.2-0.20.0
Stereotopy head waving duration, day 30.50.61.80.20.10.10.60.1-0.6-0.60.8-0.70.3-1.11.21.41.0-1.2-0.90.71.2-0.70.5-0.40.3
Locomotion velocity, session 70.50.62.31.40.80.90.81.4-0.7-1.10.4-0.11.5-0.5-0.2-1.0-0.10.20.3-0.4-0.90.10.1-0.10.0
Locomotion distance, session 70.50.62.21.50.91.00.91.4-0.8-1.30.5-0.41.4-0.4-0.0-0.9-0.00.10.5-0.3-0.80.10.2-0.30.2
Stereotopy head waving bouts, day 70.10.10.6-0.5-0.4-0.6-0.3-0.40.30.2-0.10.4-0.1-0.10.10.40.1-0.1-0.3-0.00.1-0.1-0.60.6-0.7
Stereotopy head waving duration, day 70.10.10.7-0.40.1-0.3-0.0-0.40.00.10.20.1-0.2-0.20.40.80.3-0.4-0.30.30.6-0.4-0.30.3-0.5
Locomotion velocity, session 80.20.30.60.20.60.50.40.3-0.5-0.40.4-0.6-0.3-0.60.50.10.5-0.4-0.60.50.5-0.70.8-0.80.7
Locomotion distance, session 80.40.61.80.70.50.80.91.3-0.9-0.90.5-0.00.7-1.1-0.0-1.20.4-0.1-1.1-0.7-1.20.4-0.50.5-0.4
Degree of sensitization distance0.10.10.80.40.10.20.10.1-0.0-0.30.0-0.20.6-0.10.10.1-0.1-0.00.2-0.10.2-0.00.9-0.90.9
Degree of sensitization stereotypy0.00.10.4-0.1-0.1-0.2-0.1-0.20.1-0.1-0.00.10.00.1-0.00.3-0.10.00.2-0.00.0-0.1-0.50.5-0.6
Conditioned locomotion0.30.31.40.71.01.20.80.8-0.8-0.50.6-0.9-0.5-0.10.30.10.4-0.30.10.30.1-0.40.00.0-0.0
Cocaine response after cond. corrected0.20.20.80.50.20.00.50.5-0.4-0.80.5-0.50.8-0.30.40.20.2-0.40.30.30.5-0.5-0.70.6-0.9
Cocaine response after cond. not corrected0.30.53.01.10.20.10.40.8-0.3-1.00.20.01.70.1-0.3-0.5-0.50.41.1-0.5-0.50.2-0.80.7-0.9
Cocaine response before conditioning1.11.34.10.6-0.5-0.7-0.80.10.9-0.1-1.11.61.90.8-1.4-1.3-1.61.51.4-1.5-2.01.30.0-0.10.2
Saline control response0.81.09.41.70.10.30.91.6-0.8-1.80.7-0.23.1-1.00.1-1.1-0.0-0.10.3-0.1-0.4-0.1-0.10.0-0.5
Bone: connectivity density3.86.010.22.22.82.93.02.0-3.0-2.83.2-3.1-0.4-2.32.92.72.6-2.8-0.82.12.4-1.92.0-2.11.7
Bone: cortical apparent density0.30.42.3-1.0-1.5-1.2-0.7-0.90.70.6-0.40.70.2-0.10.20.30.1-0.3-0.60.40.3-0.4-0.10.2-0.3
Bone: cortical area1.93.09.53.12.92.22.02.8-1.8-2.01.4-0.92.3-0.3-0.2-0.6-0.30.31.5-1.5-0.91.7-1.61.5-1.6
Bone: cortical porosity0.10.10.7-0.4-0.2-0.1-0.2-0.30.20.8-0.20.1-0.60.20.10.10.2-0.1-0.40.4-0.1-0.60.2-0.10.1
Bone: cortical porosity0.10.10.60.00.10.1-0.1-0.10.10.8-0.20.1-0.20.5-0.1-0.1-0.10.10.10.0-0.3-0.1-0.20.2-0.2
Bone: cortical thickness1.62.76.51.81.20.50.31.3-0.2-0.7-0.20.62.21.1-1.4-1.6-1.61.52.4-2.1-1.62.3-2.62.4-2.5
Bone: cortical thickness0.81.03.50.2-0.3-0.3-0.40.10.40.5-0.60.70.81.0-1.0-0.9-1.01.01.2-1.0-1.01.3-1.81.8-1.9
Bone: cortical tissue density0.30.52.4-1.1-1.6-1.2-0.7-1.00.70.7-0.40.70.1-0.10.20.40.2-0.3-0.70.50.4-0.5-0.10.1-0.3
Condit. Reinf. active minus inactive responses1.11.31.9-0.6-0.9-1.2-1.1-0.61.20.5-1.31.40.61.1-1.4-1.2-1.31.31.0-1.0-1.21.2-1.31.3-1.2
Condit. Reinf. active-inactive response ratio0.70.72.3-1.5-1.0-1.3-1.3-1.41.21.2-1.10.8-0.90.7-0.5-0.1-0.40.4-0.10.30.0-0.1-0.30.3-0.3
Condit. Reinf. active responses0.91.13.90.90.1-0.2-0.00.80.1-0.5-0.40.72.00.4-1.0-1.3-1.01.01.0-1.1-1.51.0-1.61.5-1.7
Condit. Reinf. inactive responses1.21.66.32.31.11.21.42.1-1.3-1.91.0-0.42.5-0.6-0.1-0.7-0.20.20.9-0.9-1.00.6-1.21.0-1.3
Incentive salience index mean2.12.84.5-0.2-0.9-1.4-1.4-0.41.40.7-1.71.91.41.6-2.1-1.9-2.02.01.7-1.9-1.92.1-2.02.0-1.9
Condit. Reinf. lever presses2.03.05.9-0.4-1.3-1.6-1.5-0.51.61.0-1.82.11.71.5-2.0-1.9-2.02.01.3-2.2-2.02.4-2.12.0-1.9
Condit. Reinf. active minus inactive responses0.71.02.51.20.40.50.51.3-0.5-1.10.10.51.60.0-0.7-1.5-0.60.70.8-1.4-1.31.1-1.41.3-1.3
Condit. Reinf. active-inactive response ratio0.20.30.80.5-0.10.30.30.6-0.2-0.70.00.40.7-0.1-0.4-0.9-0.30.40.3-0.9-0.70.6-0.80.8-0.8
Condit. Reinf. active responses1.11.64.82.21.21.31.42.1-1.3-2.11.0-0.32.2-0.5-0.2-1.0-0.20.21.0-0.9-0.90.8-1.21.1-1.3
Condit. Reinf. inactive responses0.60.83.01.71.30.91.01.5-0.9-1.50.8-0.61.6-0.2-0.0-0.2-0.20.11.1-0.2-0.20.3-0.70.6-0.8
Condit. Reinf. lever presses0.10.20.50.50.20.40.40.5-0.4-0.60.3-0.40.50.0-0.0-0.4-0.10.00.50.1-0.0-0.3-0.60.6-0.7
Condit. Reinf. lever reinforcers received0.91.23.71.80.91.01.11.8-1.0-1.80.7-0.11.9-0.3-0.3-1.0-0.30.30.9-0.9-0.80.8-1.31.1-1.3
Conditioned reinforcement - actives0.31.02.61.61.41.21.11.1-1.1-0.81.2-0.70.9-0.70.91.60.6-0.70.00.30.5-0.51.1-1.21.2
Conditioned reinforcement - inactives0.82.33.71.71.41.51.71.4-1.6-1.61.7-1.11.4-1.81.71.51.4-1.6-0.90.80.9-0.81.9-1.91.8
Conditioned locomotion1.21.83.90.91.41.11.30.7-1.3-1.01.5-1.1-0.1-1.51.72.01.5-1.6-1.11.01.2-1.21.8-1.81.5
Patch foraging indifference point 0 sec0.51.54.9-0.0-0.3-0.5-1.1-0.81.11.5-1.11.1-0.12.1-1.40.3-1.71.52.2-2.1-1.01.1-1.01.0-0.6
Patch foraging indifference point AUC0.81.99.00.4-1.2-1.7-1.0-0.21.2-0.6-1.11.93.00.6-1.2-1.2-1.61.31.6-2.1-1.61.7-0.60.5-0.9
Delay disc. indifference point, 0s delay0.80.94.91.60.70.50.41.2-0.3-1.20.00.22.20.2-0.7-1.1-0.90.81.5-1.0-1.21.0-0.40.3-0.3
Delay disc. indifference point, 16s delay0.30.53.41.30.20.40.50.8-0.4-1.50.5-0.31.8-0.3-0.00.2-0.40.11.00.0-0.1-0.10.4-0.40.3
Delay disc. indifference point, 2s delay0.20.21.30.6-0.30.10.30.3-0.3-1.00.4-0.41.1-0.40.30.40.1-0.30.30.60.4-0.60.5-0.50.1
Delay disc. indifference point, 24s delay1.42.28.20.5-1.2-1.3-1.1-0.21.3-0.1-1.31.92.91.0-1.7-1.7-2.01.81.7-1.8-1.91.9-0.50.5-0.4
Delay disc. indifference point, 4s delay0.91.05.21.3-0.0-0.1-0.10.70.2-1.1-0.30.62.30.5-1.0-0.8-1.31.11.9-1.1-1.21.0-0.20.1-0.3
Delay disc. indifference point, 8s delay0.71.23.0-0.2-1.5-1.5-1.3-0.91.40.1-1.21.31.61.1-1.3-0.5-1.61.31.7-0.6-0.70.60.0-0.0-0.1
Indifference point function ln k0.31.03.80.31.31.81.20.9-1.30.31.0-1.5-1.9-0.40.80.81.2-0.8-1.00.90.7-0.9-0.40.4-0.1
Indifference point function log k0.31.03.80.31.31.81.20.9-1.30.31.0-1.5-1.9-0.40.80.81.2-0.8-1.00.90.7-0.9-0.40.4-0.1
Patch foraging total patch changes 0 sec0.51.44.80.1-0.2-0.4-1.0-0.71.11.4-1.01.10.02.1-1.30.3-1.61.42.2-2.0-1.01.0-1.11.1-0.7
Patch foraging total patch changes 12 sec1.11.43.2-0.5-1.4-1.8-1.5-1.21.60.9-1.31.61.11.4-1.1-0.2-1.51.11.7-1.5-0.71.0-0.30.3-0.4
Patch foraging total patch changes 18 sec0.51.13.30.3-0.7-0.9-0.7-0.40.90.6-0.81.11.21.3-1.0-0.2-1.31.11.8-1.7-1.00.9-1.11.0-1.1
Patch foraging total patch changes 24 sec0.72.37.90.5-0.9-0.6-1.1-0.31.30.5-1.41.41.51.8-1.9-1.1-2.22.02.6-2.8-1.62.2-0.80.8-0.5
Patch foraging total patch changes 6 sec1.52.66.2-0.3-1.3-1.9-1.8-1.32.00.9-1.72.01.52.0-1.7-0.5-2.21.82.5-2.4-1.31.6-0.70.6-0.6
Patch foraging time to switch 0 sec0.31.15.5-1.9-1.0-0.8-1.2-1.71.11.8-1.00.3-2.31.1-0.4-0.0-0.30.4-0.00.90.7-0.40.2-0.10.4
Patch foraging water rate 0 sec0.10.51.20.90.60.50.71.1-0.7-0.70.6-0.11.1-0.70.2-0.10.3-0.3-0.5-0.8-0.60.7-1.01.0-1.1
Patch foraging water rate 12 sec0.10.21.20.61.10.50.10.3-0.1-0.2-0.0-0.2-0.30.7-0.40.0-0.40.51.1-0.5-0.3-0.0-0.60.5-0.5
Patch foraging water rate 18 sec0.10.21.10.91.01.00.50.8-0.5-0.30.3-0.20.1-0.1-0.1-0.1-0.10.20.1-0.6-0.3-0.10.2-0.30.6
Patch foraging water rate 24 sec0.91.24.12.01.71.01.01.8-0.9-1.30.6-0.32.0-0.2-0.4-0.8-0.50.50.9-1.5-0.80.6-1.00.9-0.8
Patch foraging water rate 6 sec0.10.20.5-0.00.20.20.40.1-0.40.20.5-0.6-0.5-0.40.50.40.6-0.5-0.6-0.40.7-0.5-0.10.1-0.1
Seeking ratio, delayed vs. immediate footshock0.10.21.1-0.4-0.1-0.4-0.3-0.10.20.5-0.40.4-0.40.1-0.3-0.5-0.10.2-0.4-1.0-0.50.50.3-0.30.5
Distance traveled before self-admin0.10.20.6-0.3-0.8-0.7-0.20.10.2-0.0-0.30.40.6-0.4-0.3-0.5-0.10.2-0.5-0.4-0.50.6-0.20.1-0.3
Distance traveled after self-admin1.83.26.00.70.70.91.70.8-1.7-1.72.0-2.00.2-2.32.51.92.3-2.4-1.62.02.3-1.91.9-1.91.4
Extensor digitorum longus weight0.41.86.02.01.21.20.92.0-0.8-1.50.30.32.4-0.5-0.7-2.3-0.60.80.6-1.9-2.01.9-0.20.1-0.1
Bone: elastic displacement1.82.37.3-2.7-1.9-1.2-1.0-2.10.81.7-0.40.2-2.7-0.50.91.31.2-1.1-2.31.81.2-1.81.0-0.91.0
Bone: elastic work1.82.48.6-2.0-1.3-0.5-0.1-1.3-0.01.00.4-0.5-2.2-1.41.61.81.9-1.8-2.92.01.6-2.11.3-1.21.2
Bone: endosteal estimation2.66.313.13.23.13.63.53.2-3.5-3.33.4-3.30.8-2.62.42.02.3-2.3-0.81.21.6-1.11.3-1.41.2
Bone: endosteal perimeter2.66.313.42.73.43.73.52.9-3.5-2.93.3-3.3-0.4-2.52.52.12.5-2.4-1.21.51.9-1.31.3-1.41.2
Epididymis fat weight0.42.25.62.12.42.12.22.2-2.1-1.92.0-1.80.8-1.21.21.01.2-1.2-0.1-0.70.7-0.1-0.40.3-0.4
Delta time in closed arm before/after self-admin2.32.24.6-1.5-0.6-1.4-1.7-1.51.72.1-1.81.6-1.22.1-1.5-1.0-1.41.51.0-1.2-1.11.3-1.51.6-1.4
Delta time in open arm before/after self-admin1.11.34.20.9-0.10.61.21.1-1.1-2.11.3-1.11.6-1.81.30.31.2-1.3-1.01.00.9-1.20.8-0.90.5
Diff in mean of infusions in LGA sessions0.10.10.70.00.70.60.40.3-0.40.20.2-0.1-0.9-0.40.0-0.20.3-0.1-0.6-0.2-0.40.3-0.40.4-0.1
Delay discount exponential model param0.70.95.5-0.90.50.60.5-0.2-0.60.70.6-0.8-2.4-0.71.10.71.5-1.2-1.80.91.0-0.80.00.10.1
Extinction: sum of active levers before priming0.30.51.30.30.7-0.1-0.30.20.40.2-0.60.70.40.7-1.1-0.8-1.01.10.7-0.9-1.11.0-0.70.7-0.5
Active lever presses in extinction session 60.70.72.41.61.01.31.21.5-1.2-1.21.0-0.70.8-0.50.4-0.20.4-0.30.50.3-0.1-0.0-0.10.1-0.1
Bone: final force0.61.03.51.91.61.51.21.6-1.1-1.20.8-0.71.00.0-0.1-0.1-0.20.21.2-1.0-0.31.1-0.70.6-0.6
Bone: final moment0.50.82.61.61.51.51.21.3-1.1-1.11.0-1.00.6-0.10.20.40.1-0.11.0-0.50.20.6-0.30.3-0.3
Food consumed during 24 hour testing period0.40.82.7-0.4-0.5-0.5-0.9-0.71.00.8-1.00.6-0.41.7-1.1-0.6-1.21.21.6-1.2-0.51.0-0.70.6-0.5
Glucose0.10.10.7-0.40.2-0.1-0.2-0.20.10.2-0.2-0.0-0.4-0.2-0.2-0.5-0.00.1-0.6-0.8-0.10.5-0.20.2-0.3
Heart weight0.10.21.1-0.30.3-0.1-0.2-0.60.2-0.20.1-0.1-0.3-0.10.61.00.3-0.50.1-0.30.8-0.00.5-0.50.1
Delay discount hyperbolic model param0.50.74.4-0.80.50.60.4-0.1-0.60.70.5-0.7-2.1-0.50.90.51.3-1.0-1.60.70.8-0.6-0.10.10.0
Intermittent access intake day 1-15 change0.10.73.10.71.81.40.90.5-0.9-0.20.9-0.6-0.9-0.30.81.60.7-0.7-0.2-0.10.4-0.20.5-0.50.5
Intermittent access intake escalation0.10.83.30.91.81.51.10.8-1.1-0.31.1-0.7-0.7-0.60.91.40.8-0.8-0.5-0.20.4-0.10.5-0.50.5
Intermittent access intake escalation 20.10.31.8-0.10.90.60.30.1-0.40.50.3-0.1-1.4-0.20.40.70.5-0.4-0.7-0.4-0.00.2-0.10.10.1
Intermitt. access day 1 inactive lever presses0.00.41.50.2-1.0-0.20.40.3-0.3-1.00.5-0.21.2-1.10.70.10.6-0.7-0.60.50.5-0.40.4-0.4-0.2
Intermitt. access day 15 inactive lever presses0.74.07.11.71.61.72.11.6-2.1-2.72.4-2.01.1-2.52.32.32.0-2.2-1.41.92.0-1.92.0-2.11.8
Intermitt. access escalation Index0.20.51.6-0.3-0.5-1.2-0.8-0.40.80.3-0.81.21.00.3-0.7-1.3-0.70.60.4-0.6-0.90.7-0.30.3-0.3
Intermittent access day 1 total infusions0.61.83.11.71.41.71.71.5-1.6-1.71.7-1.10.8-1.51.31.31.1-1.2-0.50.60.6-0.71.4-1.51.5
Intermittent access day 15 total infusions1.12.77.42.32.72.42.22.0-2.2-1.72.1-1.20.6-1.61.51.91.3-1.4-0.70.20.5-0.51.4-1.51.4
Intermittent access terminal intake (last 3 days)1.42.54.91.62.22.01.91.5-1.9-1.21.9-1.2-0.0-1.71.72.01.6-1.7-1.30.40.8-0.81.6-1.71.7
Intermittent access total infusions1.92.24.71.82.21.91.91.7-1.9-1.41.8-1.10.4-1.71.51.61.4-1.4-1.10.30.6-0.71.5-1.61.6
Intermittent access day 1 locomotion0.71.22.61.61.31.51.51.5-1.5-1.31.4-0.90.7-1.31.01.00.9-0.9-0.60.40.1-0.30.9-1.00.9
Intermittent access day 15 total locomotion0.83.05.51.22.12.02.11.4-2.1-1.32.2-1.8-0.8-1.92.12.32.1-2.0-1.61.11.4-1.41.4-1.51.2
Intermittent access total locomotion2.32.84.51.52.12.02.11.6-2.1-1.32.1-1.6-0.4-1.91.92.11.9-1.9-1.50.71.0-1.01.6-1.61.5
Intermittent access standard deviation0.10.72.71.21.61.31.21.1-1.1-0.81.1-0.70.2-0.70.70.90.6-0.7-0.40.30.4-0.40.3-0.40.3
Left kidney weight0.21.96.11.92.10.80.41.3-0.3-0.7-0.10.41.41.2-1.2-0.3-1.51.42.4-2.5-1.41.7-1.51.4-1.3
Right kidney weight0.53.512.11.31.3-0.1-0.70.30.80.3-1.21.41.32.5-2.2-0.8-2.52.43.3-3.5-2.22.7-1.81.6-1.3
Cocaine induced anxiety0.20.51.61.10.91.10.80.9-0.8-1.30.8-0.61.0-0.60.50.00.3-0.40.30.20.3-0.10.3-0.30.2
Post-drug Anxiety1.01.22.10.71.11.11.10.7-1.1-1.51.3-1.40.2-1.21.20.91.1-1.2-0.41.41.4-1.31.0-1.00.8
Baseline Anxiety0.61.02.6-0.30.40.50.7-0.0-0.7-0.20.9-1.3-1.3-0.81.11.11.2-1.1-1.01.61.4-1.60.9-0.80.7
Tail length0.94.916.43.10.70.80.42.1-0.2-0.9-0.30.74.01.6-2.0-1.9-2.42.23.6-3.4-2.43.1-2.52.3-2.0
Length with tail1.46.322.94.42.51.91.43.0-1.1-2.30.5-0.14.31.6-1.7-1.3-2.32.04.8-3.1-1.92.6-2.42.1-2.0
Length without tail0.83.915.43.93.62.92.43.1-2.2-2.91.8-1.72.1-0.10.1-0.0-0.30.12.7-1.0-0.20.4-0.90.8-0.9
Times rat made contact with spout0.40.52.31.1-0.00.50.40.9-0.3-0.90.10.21.50.2-0.3-0.6-0.50.41.0-0.7-0.70.8-0.60.5-0.5
Lifetime Intake1.92.34.31.72.11.91.81.5-1.8-1.41.8-1.20.2-1.61.51.71.4-1.5-0.90.50.7-0.81.8-1.92.0
Liver weight, left0.50.82.21.31.21.00.81.2-0.7-1.00.5-0.70.70.2-0.3-0.2-0.30.41.1-0.7-0.40.6-1.41.4-1.5
Liver weight, right0.91.54.32.12.11.71.71.8-1.6-1.91.5-1.11.1-0.80.80.90.5-0.60.6-0.60.20.1-0.60.5-0.7
Locomotor activity0.60.93.2-1.1-1.0-0.7-1.0-1.21.01.8-0.90.3-1.51.6-0.60.1-0.60.60.9-0.20.00.1-1.11.1-1.0
Locomotor testing distance0.61.55.6-1.6-1.3-1.3-1.5-1.81.52.4-1.30.9-1.62.1-0.70.3-0.80.81.1-0.10.10.0-0.90.9-0.7
Locomotor testing rearing0.10.30.90.10.2-0.0-0.10.10.10.9-0.20.3-0.40.8-0.4-0.3-0.40.50.6-0.3-0.60.7-0.90.9-0.8
Locomotion in novel chamber1.21.63.70.31.11.41.61.1-1.8-0.11.6-1.7-1.6-1.31.50.51.9-1.6-1.90.91.0-1.00.1-0.0-0.1
Locomotion in novel chamber post-restriction0.51.45.12.11.41.31.62.2-1.5-1.01.1-0.91.7-0.7-0.0-0.80.10.00.1-0.6-0.60.6-1.31.2-1.0
Fecal boli incidents, locomotor time 10.20.52.20.40.60.20.30.5-0.3-0.70.20.10.7-0.90.4-0.10.4-0.4-0.7-0.3-0.30.51.5-1.41.5
Change in fecal boli incidents, locomotor task0.60.61.2-0.3-1.0-0.6-0.8-0.60.90.6-0.90.90.11.1-0.9-0.6-1.01.01.1-0.6-0.70.5-0.80.8-0.8
Time >=10cm from walls, locomotor time 11.31.65.62.31.61.31.32.3-1.2-1.90.7-0.62.4-0.7-0.6-1.7-0.50.60.7-1.0-0.91.0-0.60.6-0.6
Bouts of movement, locomotor time 10.50.63.00.10.70.4-0.2-0.20.21.3-0.40.2-1.41.7-0.60.4-0.60.71.5-0.7-0.60.6-0.70.7-0.4
Total resting periods, locomotor time 10.50.53.30.60.80.5-0.00.10.10.8-0.20.1-0.81.6-0.50.4-0.70.71.8-0.7-0.60.5-0.60.5-0.3
Rest time, locomotor task time 10.20.31.3-0.5-0.2-0.1-0.4-0.80.40.8-0.10.0-1.10.60.41.00.2-0.30.30.40.5-0.50.6-0.60.5
Distance moved, locomotor task time 10.51.35.70.7-0.9-0.6-0.30.70.4-1.4-0.71.02.40.0-1.4-2.0-1.31.30.9-1.2-1.51.5-0.60.6-0.5
Vertical activity count, locomotor time 10.00.10.50.1-0.00.0-0.00.20.0-0.3-0.20.20.20.1-0.5-0.7-0.40.50.0-0.2-0.50.4-0.10.10.2
Time >=10cm from walls, locomotor time 20.41.38.01.50.1-0.10.11.10.0-1.3-0.30.62.8-0.0-1.0-1.7-1.21.11.2-1.5-1.31.5-0.10.0-0.1
Bouts of movement, locomotor time 20.31.12.5-1.0-1.2-1.1-1.5-1.31.51.0-1.41.6-0.31.1-1.0-0.3-1.11.10.8-1.0-0.90.90.3-0.30.4
Total resting periods, locomotor time 20.41.53.0-1.0-1.2-1.1-1.6-1.41.71.4-1.61.7-0.51.5-1.3-0.4-1.41.31.1-1.2-1.11.10.2-0.20.3
Rest time, locomotor task time 20.61.14.8-0.40.00.0-0.9-0.80.91.7-1.10.6-1.72.2-1.1-0.0-1.21.21.7-0.7-0.90.9-0.40.4-0.1
Distance moved, locomotor task time 20.81.08.11.0-0.5-0.40.41.2-0.3-1.70.20.52.8-1.1-0.4-1.6-0.30.3-0.3-0.7-1.01.0-0.70.6-0.8
Vertical activity count, locomotor time 20.20.41.9-0.2-0.7-0.7-0.3-0.20.4-0.8-0.20.71.4-0.8-0.0-0.4-0.1-0.1-0.60.0-0.20.20.8-0.90.8
Light reinforcement 10.20.92.60.40.71.20.90.3-0.9-1.01.0-1.3-1.2-0.31.11.60.9-1.00.20.61.2-0.60.9-0.90.9
Light reinforcement 20.51.23.6-1.9-1.4-0.9-0.9-1.90.80.6-0.40.0-1.8-0.00.81.40.7-0.8-0.80.81.6-1.11.0-0.90.8
Bone: marrow area2.87.014.13.33.23.83.73.3-3.7-3.43.5-3.40.8-2.72.62.22.5-2.5-0.91.21.7-1.21.4-1.51.2
Bone: maximum diameter4.69.222.44.14.74.64.54.4-4.4-4.04.1-3.71.2-3.12.61.72.6-2.5-0.90.91.3-0.70.3-0.40.0
Bone: maximum force1.01.95.72.42.32.32.12.2-2.0-1.81.8-1.50.9-0.80.90.70.7-0.70.5-0.30.20.5-0.30.2-0.3
Bone: maximum moment0.91.84.82.12.22.22.01.8-1.9-1.71.8-1.70.5-0.81.11.10.9-1.00.40.10.60.10.0-0.10.0
Mean time between licks in bursts0.21.14.2-2.0-1.4-1.5-1.4-1.91.41.9-1.11.0-1.40.7-0.30.1-0.20.2-0.80.30.30.0-0.20.4-0.3
Mean num. licks in bursts1.23.39.12.11.41.92.42.4-2.3-2.72.3-1.52.1-3.01.90.51.9-1.9-1.91.00.6-0.61.0-1.00.7
Cd content in liver1.11.23.8-1.9-1.1-1.7-1.6-1.91.61.9-1.31.3-1.21.0-0.60.2-0.60.5-0.20.0-0.40.1-0.10.1-0.0
Co content in liver0.70.92.5-1.2-0.9-1.0-0.3-1.00.30.20.1-0.1-0.5-1.01.00.91.0-1.1-1.61.41.4-1.20.9-0.90.6
Cu content in liver1.01.24.3-1.3-1.5-1.0-0.8-1.70.80.2-0.2-0.4-1.20.40.71.50.3-0.60.31.82.1-1.41.2-1.10.8
Fe content in liver1.01.23.1-1.3-1.8-1.3-1.5-1.51.51.2-1.41.2-0.61.3-1.1-0.6-1.11.10.8-0.7-0.41.0-0.30.3-0.1
K content in liver0.20.20.8-0.4-0.8-0.4-0.5-0.30.50.6-0.60.20.10.3-0.4-0.9-0.30.4-0.0-0.00.2-0.10.3-0.30.3
Mg content in liver0.10.21.1-0.6-1.0-0.6-0.5-0.50.50.3-0.40.10.10.1-0.1-0.3-0.10.1-0.10.30.5-0.1-0.10.1-0.2
Mn content in liver0.60.61.9-1.2-1.1-1.1-1.2-1.41.21.2-1.00.7-0.71.0-0.5-0.1-0.60.50.5-0.00.2-0.1-0.10.10.0
Na content in liver0.80.92.2-0.7-1.4-1.2-1.1-0.61.20.5-1.21.10.50.8-1.2-1.5-1.11.20.6-0.6-0.60.2-0.70.7-0.7
Rb content in liver0.10.10.70.40.00.50.30.4-0.3-0.30.2-0.4-0.10.3-0.2-0.3-0.20.20.6-0.40.20.8-0.30.2-0.2
Se content in liver12.715.034.9-5.6-5.8-5.7-5.7-5.95.74.9-5.14.5-2.34.1-3.1-1.4-3.23.01.5-1.1-0.81.3-1.01.1-0.8
Sr content in liver1.81.54.0-1.0-0.2-0.20.3-0.6-0.4-0.40.8-0.9-1.2-1.41.61.71.6-1.7-1.81.92.0-1.90.9-0.80.5
Zn content in liver3.54.110.1-2.7-3.2-3.1-2.9-2.62.92.6-2.72.6-0.41.8-1.8-1.6-1.71.70.2-0.8-0.91.1-0.70.8-0.6
Bone: minimum diameter2.24.313.43.53.73.33.13.4-3.0-2.62.6-2.21.5-1.61.20.51.1-1.00.1-0.40.10.6-0.10.0-0.1
Time in familiar zone, hab. session 10.20.20.80.10.20.30.3-0.0-0.30.10.4-0.5-0.5-0.00.60.50.5-0.60.10.90.6-0.70.3-0.30.2
Time in novel zone, hab. session 10.50.51.0-0.9-0.9-0.8-1.0-0.91.00.9-1.00.8-0.50.8-0.8-0.4-0.70.80.1-0.7-0.40.5-0.10.10.1
Total zone transitions, hab. session 10.10.10.50.20.10.40.30.2-0.3-0.70.3-0.5-0.4-0.00.30.40.3-0.30.30.50.5-0.7-0.20.2-0.5
Total locomotion distance, hab. session 10.30.51.3-0.9-1.1-0.5-0.7-0.70.70.7-0.70.4-0.90.9-0.5-0.4-0.40.50.50.3-0.4-0.4-0.90.9-1.0
Locomotion velocity, hab. session 10.40.61.8-0.9-1.3-0.7-0.8-0.70.80.6-0.90.7-0.60.7-0.7-0.6-0.50.70.4-0.1-0.70.0-0.90.9-1.0
Time in familiar zone, hab. session 20.20.20.7-0.7-0.5-0.5-0.5-0.80.50.8-0.3-0.1-0.60.30.20.40.1-0.2-0.20.40.7-0.40.2-0.10.2
Time in novel zone, hab. session 20.10.10.30.10.30.20.20.2-0.2-0.50.2-0.00.0-0.40.20.10.2-0.2-0.30.1-0.00.00.3-0.30.2
Total zone transitions, hab. session 20.50.61.4-0.7-0.7-0.8-0.8-0.80.90.4-0.80.6-0.41.1-0.7-0.2-0.80.71.1-0.4-0.30.2-1.11.0-1.2
Total locomotion distance, hab. session 20.71.01.8-1.3-1.0-1.0-1.2-1.21.11.1-1.10.8-1.31.2-0.9-0.4-0.70.80.6-0.3-0.50.1-1.21.2-1.2
Locomotion velocity, hab. session 20.81.11.9-1.2-1.0-1.0-1.2-1.11.21.3-1.20.9-1.21.4-1.1-0.7-0.91.00.8-0.5-0.80.4-1.31.3-1.2
Novel to familiar place preference ratio0.50.71.61.10.91.21.00.9-1.0-1.31.0-0.80.1-0.60.71.00.6-0.60.30.20.30.00.9-0.90.9
Novelty place preference0.60.81.61.00.91.31.10.9-1.1-1.21.1-1.0-0.1-0.70.91.10.8-0.80.10.40.5-0.11.1-1.11.1
Time in novel zone, NPP test0.40.51.50.60.71.10.70.4-0.7-0.70.7-0.8-0.7-0.20.71.00.5-0.60.20.30.5-0.11.2-1.11.2
Total zone transitions, NPP test0.81.32.4-0.7-1.1-1.0-1.3-0.81.31.0-1.41.0-0.01.6-1.4-1.2-1.41.41.3-0.8-0.90.3-1.21.2-1.1
Total locomotion distance, NPP test0.91.23.2-1.2-1.8-1.3-1.3-1.01.31.0-1.31.0-0.11.1-1.2-1.1-1.01.10.5-0.8-0.70.6-1.41.3-1.3
Locomotion velocity, NPP test0.91.32.7-0.7-1.7-1.2-1.1-0.61.10.7-1.21.10.61.0-1.2-1.3-1.11.20.7-1.1-1.00.9-1.61.5-1.5
Intraocular pressure0.10.20.80.40.20.90.50.3-0.5-0.50.5-0.7-0.70.20.20.50.2-0.20.5-0.80.2-0.00.3-0.30.4
Delta distance traveled before/after self-admin3.43.75.91.52.11.92.21.5-2.2-2.12.4-2.30.2-2.22.42.02.2-2.3-1.31.72.0-1.81.6-1.61.4
Delta ambulatory time before/after self-admin2.84.97.92.12.32.22.62.0-2.6-2.72.8-2.41.0-2.72.72.02.4-2.6-1.41.82.1-1.81.8-1.81.5
Parametrial fat weight2.15.010.90.1-0.8-1.3-1.8-0.51.91.2-2.32.61.52.7-2.8-2.3-2.92.92.9-2.8-2.83.3-2.22.1-2.0
Pavlov. Cond. lever latency1.62.04.8-0.30.60.80.7-0.4-0.8-0.21.2-1.5-1.9-0.81.72.21.6-1.7-1.02.02.2-2.01.5-1.51.3
Pavlov. Cond. magazine entry latency2.02.54.1-0.9-0.8-1.5-1.6-0.91.71.5-1.92.00.51.5-2.0-1.8-1.91.90.9-1.8-1.91.7-1.81.8-1.4
Pavlov. Cond. change in total contacts2.52.74.7-1.0-1.3-1.8-1.7-1.01.81.2-1.92.20.71.6-1.9-1.6-1.81.81.2-1.6-1.91.7-1.91.9-1.7
Pavlov. Cond. index score2.83.56.8-0.1-0.6-1.2-1.4-0.21.41.0-1.92.11.41.7-2.4-2.5-2.32.41.5-2.5-2.62.5-2.22.2-1.8
Pavlov. Cond. latency score2.93.77.60.2-0.5-1.1-1.20.21.20.7-1.72.01.91.5-2.4-2.7-2.32.41.6-2.7-2.72.6-2.42.3-2.0
Pavlov. Cond. lever contacts2.12.55.1-0.0-0.9-1.2-1.2-0.11.20.6-1.51.91.71.2-2.0-2.2-1.91.91.3-2.2-2.32.2-1.71.7-1.4
Pavlov. Cond. magazine entry number1.31.72.81.00.41.21.40.9-1.4-1.71.6-1.50.2-1.51.61.21.5-1.6-0.61.31.4-1.31.4-1.41.0
Pavlov. Cond. intertrial magazine entries0.50.52.11.50.50.80.91.3-0.8-1.20.7-0.41.4-0.20.0-0.2-0.10.10.8-0.3-0.40.3-0.50.4-0.6
Pavlov. Cond. lever-magazine prob. diff.3.03.76.7-0.4-0.9-1.5-1.6-0.51.71.3-2.12.31.21.8-2.5-2.4-2.32.41.5-2.4-2.62.4-2.22.1-1.7
Pavlov. Cond. response bias1.82.23.6-1.3-1.0-1.6-1.8-1.31.81.8-1.91.8-0.11.7-1.8-1.4-1.71.70.8-1.4-1.51.5-1.41.4-1.0
Pavlov. Cond. lever latency0.10.10.7-0.30.10.3-0.2-0.10.10.7-0.30.3-0.80.2-0.2-0.3-0.10.2-0.2-0.6-0.50.60.3-0.20.5
Pavlov. Cond. magazine entry latency0.81.21.9-0.9-1.0-1.4-1.3-1.01.40.9-1.41.30.11.2-1.2-1.2-1.21.20.9-0.6-1.00.6-1.01.0-1.1
Pavlov. Cond. change in total contacts0.20.53.50.6-0.3-0.4-0.10.50.2-0.6-0.20.51.90.0-0.6-1.1-0.70.60.6-0.5-0.80.2-0.70.7-0.8
Pavlov. Cond. index score0.30.41.70.4-0.2-0.5-0.20.20.3-0.4-0.40.41.30.4-0.7-0.8-0.80.70.9-0.4-0.70.3-1.00.9-1.1
Pavlov. Cond. latency score0.20.31.40.5-0.0-0.3-0.00.40.1-0.5-0.10.21.20.2-0.5-0.7-0.60.50.8-0.3-0.60.1-0.90.9-1.1
Pavlov. Cond. lever contacts0.10.10.70.2-0.0-0.30.10.1-0.1-0.70.2-0.30.8-0.30.20.10.1-0.20.10.50.4-0.5-0.30.2-0.5
Pavlov. Cond. magazine entry number1.31.72.60.81.31.61.50.9-1.5-0.91.6-1.6-0.7-1.31.51.61.5-1.5-1.10.91.4-0.81.3-1.31.4
Pavlov. Cond. intertrial magazine entries0.40.82.61.61.01.30.91.4-0.8-1.00.5-0.40.90.2-0.4-0.6-0.50.51.3-1.2-0.71.3-0.50.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.51.40.3-0.3-0.6-0.40.10.4-0.2-0.50.51.20.5-0.8-0.9-0.90.81.0-0.5-0.80.3-1.11.0-1.2
Pavlov. Cond. response bias0.30.41.1-0.3-0.7-1.0-0.7-0.50.80.0-0.70.70.90.5-0.6-0.6-0.70.60.7-0.1-0.40.0-0.70.6-0.8
Time in closed arm before self-admin0.10.10.6-0.2-0.6-0.1-0.2-0.30.20.2-0.10.1-0.30.00.20.10.1-0.1-0.10.20.2-0.30.6-0.70.8
Time in closed arm after self-admin1.31.52.8-1.1-1.5-1.5-1.5-1.21.51.7-1.61.3-0.01.6-1.3-1.4-1.31.30.9-0.8-0.90.9-1.01.0-0.8
Time in open arm before self-admin0.20.21.6-0.80.0-0.3-0.2-0.60.20.7-0.1-0.2-1.30.10.21.00.3-0.2-0.40.20.4-0.0-0.20.2-0.3
Time in open arm after self-admin1.51.63.00.60.91.11.30.7-1.4-1.51.6-1.7-0.5-1.31.61.71.4-1.5-0.61.51.6-1.71.0-1.00.7
Bone: periosteal estimation2.66.215.13.83.93.93.73.7-3.6-3.43.3-3.01.5-2.11.91.41.7-1.70.10.30.9-0.00.3-0.40.1
Bone: periosteal perimeter2.03.910.83.13.33.22.93.2-2.9-2.62.5-2.21.2-1.51.20.61.2-1.10.1-0.00.30.2-0.1-0.0-0.2
Bone: post-yield work1.11.96.32.52.01.61.31.8-1.1-1.70.9-0.41.80.4-0.3-0.1-0.60.52.2-1.4-0.91.7-1.10.9-1.0
Progressive ratio test 1 active lever presses2.13.65.61.61.82.12.21.6-2.2-1.92.4-2.10.3-2.32.12.12.0-2.1-1.61.61.7-1.71.8-1.81.9
Progressive ratio test 1 breakpoint1.83.15.01.61.71.92.11.6-2.1-1.82.2-1.90.4-2.12.01.91.9-2.0-1.41.41.5-1.61.6-1.61.7
Progressive ratio test 1 inactive lever presses0.82.14.01.71.51.51.51.2-1.5-1.81.7-0.90.8-1.51.62.01.2-1.5-0.30.70.8-0.81.9-2.01.9
Progressive ratio test 2 active lever presses3.55.08.42.42.82.72.92.3-2.9-2.42.9-2.30.3-2.42.32.82.2-2.3-1.41.11.5-1.41.8-1.91.8
Progressive ratio test 2 breakpoint4.25.49.12.52.92.83.02.4-3.0-2.53.0-2.40.3-2.62.52.92.3-2.4-1.51.21.6-1.51.9-2.01.9
Progressive ratio test 2 inactive lever presses1.23.97.21.51.91.92.11.4-2.1-1.92.3-1.80.0-2.32.32.72.1-2.3-1.71.51.8-1.72.2-2.32.2
Incentive Sensitization - Responses0.92.55.72.12.42.22.11.8-2.1-2.02.0-1.20.3-1.51.52.31.3-1.4-0.30.10.5-0.41.2-1.31.2
Incentive Sensitization - Breakpoint1.22.86.42.32.52.32.21.9-2.2-2.12.1-1.30.4-1.61.62.31.4-1.5-0.30.30.6-0.51.3-1.41.3
Sum of active levers in priming session hrs 5-60.50.41.5-0.8-0.9-0.6-0.6-1.10.60.4-0.30.3-0.40.30.40.30.1-0.30.41.20.8-1.00.9-0.80.6
Progressive ratio0.30.92.70.00.1-0.8-0.50.10.50.6-0.91.00.11.0-1.3-1.5-1.11.30.7-1.7-1.51.5-0.60.6-0.4
Food seeking constrained by brief footshock0.40.52.10.61.41.00.30.7-0.30.4-0.1-0.2-0.80.7-0.9-0.6-0.70.90.6-1.1-0.91.0-0.20.20.3
Seeking ratio, punishment vs. effort0.00.10.3-0.0-0.10.5-0.1-0.20.10.1-0.1-0.3-0.20.2-0.20.4-0.30.20.40.20.3-0.20.1-0.10.2
Retroperitoneal fat weight0.10.41.30.90.70.40.50.8-0.5-0.60.4-0.20.70.2-0.0-0.1-0.10.10.7-1.0-0.31.0-1.11.1-1.1
Reaction time number correct0.51.63.91.61.72.01.71.6-1.7-1.41.6-2.00.4-1.11.10.31.1-1.1-0.41.31.0-0.80.8-0.80.8
Reaction time mean minus median0.10.42.1-0.80.6-0.30.0-0.6-0.10.80.3-0.2-1.4-0.20.61.20.7-0.7-1.00.30.8-0.80.2-0.20.4
Reaction time mean minus median AUC0.10.51.3-0.9-0.0-0.6-0.1-0.70.00.50.2-0.2-1.1-0.30.61.10.7-0.7-1.00.21.1-1.00.5-0.50.5
Reaction time num false alarms0.40.72.01.40.51.00.61.3-0.6-0.70.20.11.10.2-0.7-0.9-0.60.71.1-1.1-1.40.9-0.60.6-0.8
Reaction time num false alarms AUC0.40.82.50.90.20.60.10.8-0.00.1-0.30.50.80.9-1.1-1.1-1.11.11.4-1.5-1.61.0-0.80.8-0.9
Reaction time trials correct on left0.51.63.91.61.72.01.71.6-1.7-1.41.6-2.00.4-1.11.10.31.1-1.1-0.41.31.0-0.80.8-0.80.8
Reaction time trials on left0.51.63.81.61.61.91.71.6-1.6-1.31.6-1.90.5-1.11.10.31.0-1.0-0.41.30.9-0.70.7-0.70.7
Reaction time mean0.91.96.9-2.6-1.7-2.3-1.9-2.31.82.1-1.51.3-1.81.0-0.60.1-0.50.5-0.8-0.10.1-0.2-0.20.3-0.3
Reaction time mean AUC0.92.28.5-2.9-2.0-2.5-2.1-2.62.02.3-1.71.4-2.00.9-0.60.1-0.40.4-1.0-0.00.1-0.20.00.1-0.0
Median of all reaction times1.52.38.5-2.9-2.2-2.4-2.1-2.52.02.2-1.81.3-1.91.1-0.7-0.1-0.50.6-0.90.10.1-0.2-0.10.2-0.2
Reaction time omissions0.20.31.8-0.4-0.3-0.9-0.2-0.10.20.2-0.20.50.5-0.1-0.4-0.4-0.20.2-0.3-0.1-0.30.2-1.21.2-1.3
Reaction time false alarm rate0.71.03.00.3-0.4-0.1-0.40.20.40.4-0.71.10.51.1-1.2-1.0-1.21.31.4-1.7-1.71.1-1.01.0-1.1
Reaction time premature initiation rate0.20.42.21.21.50.80.60.9-0.6-0.70.4-0.40.30.3-0.2-0.1-0.30.30.9-0.5-0.4-0.10.2-0.20.3
Reaction time premature initiations0.51.56.62.22.62.11.71.9-1.6-1.51.3-1.60.6-0.30.40.10.3-0.30.80.20.1-0.40.6-0.60.7
Std. dev. reaction times0.20.62.3-1.5-0.5-1.4-0.9-1.30.81.3-0.60.6-1.20.4-0.10.7-0.0-0.0-0.6-0.20.4-0.5-0.30.3-0.2
Reaction time trials completed0.51.63.81.61.61.91.71.6-1.6-1.31.6-1.90.5-1.11.10.31.0-1.0-0.41.30.9-0.70.7-0.70.7
Reaction time trials AUC0.31.23.01.41.41.71.41.4-1.4-1.21.3-1.70.5-0.90.90.10.9-0.8-0.31.20.7-0.60.6-0.60.6
Run reversals in cocaine runway, females0.40.41.7-0.7-0.00.10.1-0.5-0.10.70.3-0.6-1.3-0.00.81.10.8-0.8-0.71.11.0-0.90.2-0.10.3
Run reversals in cocaine runway, males0.80.92.1-0.5-0.4-0.7-0.9-0.71.01.1-1.01.0-0.41.4-1.2-0.6-1.21.21.2-0.6-0.91.0-0.90.8-0.3
Latency to leave start box in cocaine runway0.71.02.81.10.40.61.41.7-1.4-1.41.2-0.71.0-1.60.5-0.20.9-0.6-1.2-0.2-0.30.3-1.11.1-1.1
Latency to leave start box in cocaine runway, F0.50.61.50.7-0.20.30.81.2-0.8-0.80.50.21.0-1.00.1-0.50.3-0.2-0.8-0.8-0.80.9-1.21.2-1.1
Latency to leave start box in cocaine runway, M0.70.61.70.81.00.81.11.1-1.1-1.01.1-1.30.1-0.90.60.30.7-0.6-0.60.50.5-0.6-0.40.4-0.5
Std. dev. time between licks in bursts1.01.95.6-2.4-1.7-1.8-2.0-2.31.92.3-1.71.3-1.71.3-0.70.0-0.70.7-0.20.10.1-0.10.10.00.2
Total sessions with >9 infusions0.20.31.30.60.40.00.0-0.00.0-0.20.10.40.7-0.00.11.1-0.2-0.00.4-0.2-0.10.20.9-1.01.1
Short access day 1 total inactive lever presses1.12.34.61.01.01.21.60.9-1.6-1.41.9-1.5-0.1-1.72.12.11.9-2.0-0.91.51.6-1.51.5-1.51.1
Short access day 10 total inactive lever presses0.10.76.00.9-0.7-0.8-0.20.40.3-0.8-0.30.72.40.3-0.4-0.7-0.80.51.4-0.5-0.70.8-0.60.5-0.7
Short access day 1 total infusions0.10.21.40.4-0.1-0.2-0.0-0.20.1-0.10.20.20.5-0.20.30.8-0.0-0.20.20.00.2-0.21.1-1.11.2
Short access day 10 total infusions0.40.63.9-0.10.00.2-0.1-0.40.10.10.20.3-0.2-0.50.71.10.4-0.6-0.60.30.3-0.41.7-1.72.0
Short access total infusions0.91.24.21.01.11.10.90.6-0.9-0.81.1-0.60.1-1.01.11.50.8-1.0-0.40.60.7-0.71.9-1.92.1
Short access day 1 locomotion0.10.11.1-0.0-0.2-0.6-0.2-0.30.20.3-0.00.70.3-0.20.11.00.0-0.1-0.6-0.3-0.40.40.1-0.20.2
Short access day 10 total locomotion0.00.10.8-0.6-0.3-0.1-0.2-0.30.10.9-0.10.4-0.70.00.10.10.2-0.1-0.70.1-0.20.3-0.20.20.0
Short access total locomotion0.20.21.2-0.7-0.5-0.5-0.4-0.70.40.8-0.20.6-0.6-0.00.31.10.2-0.3-0.60.1-0.10.10.4-0.30.4
One hour access (0.3 mA shock)4.04.711.02.73.32.92.92.4-2.8-2.42.8-2.20.3-2.22.12.61.9-2.0-1.10.91.3-1.31.5-1.61.5
Compulsive drug intake0.30.52.81.20.50.30.51.0-0.5-1.20.3-0.21.7-0.4-0.1-0.3-0.20.20.4-0.7-0.50.4-0.50.4-0.7
One hour access (shock baseline)0.82.15.71.22.42.01.61.0-1.6-0.81.6-1.4-1.1-0.91.31.91.2-1.3-0.60.81.1-1.01.7-1.71.9
Social response proportion1.51.93.9-0.60.60.80.9-0.1-1.00.01.2-1.5-2.0-1.11.71.51.9-1.8-1.91.81.8-1.61.3-1.21.0
Social responses1.31.73.90.31.21.11.10.3-1.1-0.51.4-1.5-1.2-0.91.72.01.6-1.6-1.11.31.5-1.21.6-1.51.3
Social time0.50.81.6-0.8-0.9-1.3-1.2-1.11.21.2-1.11.2-0.21.1-0.9-0.4-1.00.90.7-0.9-0.61.00.1-0.10.2
Soleus weight1.13.25.51.32.11.92.21.6-2.2-2.02.3-2.3-0.1-2.32.21.62.2-2.2-1.61.41.8-1.11.0-1.00.6
Bone: stiffness1.22.17.62.82.42.11.62.4-1.5-1.51.0-0.71.8-0.0-0.3-0.8-0.40.41.5-1.7-1.21.9-0.60.5-0.4
Tibialis anterior weight0.62.18.62.51.31.51.42.6-1.3-1.90.8-0.12.9-1.1-0.3-2.1-0.10.30.1-1.3-1.81.30.0-0.10.0
Time to tail flick, vehicle, before self-admin0.81.02.2-1.0-0.3-0.4-0.0-0.8-0.10.10.4-0.4-1.2-0.81.11.31.1-1.2-1.41.11.2-1.31.5-1.41.4
Time to tail flick, vehicle, after self-admin1.12.36.31.00.1-0.1-0.60.60.70.5-1.11.61.41.7-1.9-1.9-1.92.02.1-2.2-2.52.1-1.31.3-1.1
Time to tail flick, test, before self-admin0.80.92.01.11.41.31.41.3-1.4-0.91.3-1.10.5-1.31.00.21.1-1.0-1.10.30.3-0.2-0.20.2-0.1
Time to tail flick, test, after self-admin0.30.32.2-0.1-1.2-0.7-0.5-0.30.50.2-0.40.71.5-0.1-0.2-0.4-0.30.20.0-0.4-0.30.3-0.10.1-0.2
Delta time to tail flick, vehicle, before/after SA3.43.67.62.40.80.90.32.0-0.2-0.4-0.50.92.41.5-2.1-2.6-2.12.22.7-2.5-2.72.6-2.01.9-1.7
Delta time to tail flick, test, before/after SA0.30.41.2-0.4-1.1-0.9-0.9-0.70.90.4-0.80.90.60.6-0.6-0.3-0.80.70.7-0.6-0.50.50.1-0.1-0.0
Tibia length0.20.52.80.80.30.40.10.5-0.0-0.2-0.0-0.20.51.0-0.6-0.4-0.80.71.7-0.7-0.00.8-1.01.0-1.0
Ambulatory time before self-admin0.10.31.0-0.9-1.0-1.0-0.6-0.50.60.5-0.70.8-0.0-0.0-0.4-0.5-0.20.3-0.6-0.5-0.60.6-0.30.3-0.5
Ambulatory time after self-admin1.93.06.40.91.11.21.91.2-1.9-1.82.1-1.80.3-2.52.41.82.3-2.4-1.91.51.7-1.41.5-1.51.0
Bone: tissue strength0.30.31.1-0.8-0.2-0.5-0.6-1.00.60.6-0.40.0-0.80.30.20.60.0-0.1-0.00.40.7-0.30.8-0.70.8
Total heroin consumption0.40.51.91.41.11.10.70.9-0.7-1.30.6-0.40.60.10.30.3-0.0-0.11.40.3-0.0-0.10.4-0.50.3
Bone: trabecular number3.05.610.72.73.33.23.12.3-3.0-2.73.2-3.2-0.2-1.72.52.42.2-2.40.01.82.2-1.71.5-1.51.2
Bone: trabecular spacing2.02.95.0-0.9-1.7-2.0-1.9-1.02.01.3-2.12.21.31.6-2.1-2.2-2.12.11.3-1.5-1.81.2-1.51.5-1.4
Bone: trabecular thickness2.23.07.72.12.82.72.31.9-2.3-2.12.2-2.3-0.3-1.11.61.81.4-1.50.30.91.2-0.81.1-1.21.1
Bone: trabecular tissue density1.22.14.51.91.41.82.12.1-2.1-2.12.0-1.21.1-2.01.40.71.5-1.4-1.00.40.3-0.40.3-0.40.1
Water consumed over 24 hours0.51.03.00.8-0.40.2-0.30.40.4-0.0-0.70.71.21.1-1.1-1.7-1.21.21.6-1.3-1.41.4-0.60.5-0.4
Number of responses in last shaping day0.50.74.30.20.3-0.10.4-0.1-0.4-0.50.7-0.30.0-0.71.02.10.8-1.0-0.51.10.8-1.01.0-1.00.7