Pcbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye alternative TSS XM_063263981.1 0.23 0.14 8.0e-03 0.01 0.02 -0.02 0.02 2.6e-01 1.7e-01 6.9e-01 1.8e-01
2 PL intron excision ratio chr7_135498844_135500312 0.05 0.03 2.4e-04 0.03 0.03 0.03 0.04 1.2e-04 1.2e-04 1.2e-04 3.7e-05
3 NAcc isoform ratio XM_063263998.1 0.01 0.01 6.3e-03 0 0.01 0 0 3.3e-01 1.6e-02 6.3e-02 1.6e-01
4 Eye alternative TSS XM_063263975.1 0.31 0.17 4.0e-03 0 0.03 0.05 0.05 2.9e-01 1.2e-01 5.7e-02 5.4e-02
5 NAcc intron excision ratio chr7_135498844_135500312 0.01 0.01 5.5e-03 0 0.01 0.01 0 2.7e-01 2.1e-02 1.5e-02 9.4e-02
6 Brain mRNA stability Pcbp2 0.02 0.02 7.1e-03 0.01 0.02 0.02 0.02 1.5e-02 4.1e-03 8.2e-03 1.0e-02
7 Brain intron excision ratio chr7_135498844_135500312 0.03 0.03 6.3e-03 0.04 0.02 0.03 0.03 1.8e-04 3.0e-03 1.6e-03 1.1e-03
8 Eye alternative TSS XM_063263975.1 0.31 0.18 3.5e-03 0 0.03 0.06 0.05 2.9e-01 1.2e-01 4.9e-02 5.5e-02
9 Eye gene expression Pcbp2 0.74 0.16 4.2e-04 0.26 0.18 0.24 0.24 6.1e-05 1.1e-03 1.4e-04 1.4e-04
10 Eye intron excision ratio chr7_135486791_135487387 0.82 0.07 6.7e-10 0.51 0.46 0.48 0.52 1.5e-09 2.2e-08 7.9e-09 1.3e-09
11 Eye mRNA stability Pcbp2 0.51 0.17 1.4e-03 0.26 0.18 0.19 0.26 8.0e-05 1.1e-03 8.4e-04 7.8e-05
12 IC intron excision ratio chr7_135498844_135500312 0.11 0.08 8.0e-03 0.05 0.02 0.06 0.06 4.6e-03 5.0e-02 2.3e-03 1.9e-03
13 Eye intron excision ratio chr7_135487017_135487387 0.82 0.07 4.0e-10 0.52 0.46 0.47 0.51 1.0e-09 2.1e-08 1.6e-08 2.0e-09
14 pVTA intron excision ratio chr7_135497657_135498772 0.07 0.06 9.6e-03 0.02 0.01 0 0.01 1.2e-02 7.9e-02 3.1e-01 3.1e-02
15 NAcc intron excision ratio chr7_135497657_135498772 0.03 0.01 3.3e-03 0.02 0.01 0 0.01 7.8e-04 3.2e-02 5.2e-02 8.3e-03
16 pVTA intron excision ratio chr7_135494803_135497616 0.05 0.03 5.0e-04 0.04 0.02 0.03 0.04 2.8e-04 6.8e-03 2.0e-03 7.7e-04
17 Liver isoform ratio XM_063263995.1 0.19 0.12 2.7e-03 0.02 0.01 0.01 0.02 1.0e-03 1.6e-02 1.8e-02 6.5e-03
18 NAcc isoform ratio XM_017595007.3 0.04 0.03 4.0e-03 0.01 0.01 0 0 3.0e-02 2.8e-02 5.9e-02 6.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.61.13.3-1.7-1.3-1.71.8-1.6-1.3-0.51.6-0.40.50.5-0.6-0.5-0.4-0.40.40.3-0.2
Area under the delay curve0.60.71.3-0.8-1.0-0.70.5-0.4-0.8-1.10.7-0.90.90.9-0.5-0.9-1.0-1.01.10.2-0.6
BMI with tail1.34.57.5-2.7-2.6-2.72.7-2.5-2.4-1.72.2-1.91.81.8-2.3-1.8-1.7-1.71.92.0-0.6
BMI without tail0.61.93.3-1.8-1.3-1.71.8-1.5-1.7-1.11.6-1.41.31.2-1.3-1.3-1.1-1.11.01.2-0.7
Body weight0.41.93.7-1.9-1.7-1.81.9-1.4-1.6-1.31.8-1.31.31.2-0.9-1.3-1.2-1.21.30.6-0.5
Weight adjusted by age0.20.41.50.90.61.0-0.91.20.80.4-0.70.1-0.2-0.20.50.20.00.0-0.2-0.40.4
Bone surface1.62.96.6-2.5-2.1-2.62.4-2.4-2.1-1.22.2-1.11.21.2-1.2-1.2-1.2-1.21.30.9-0.8
Bone volume1.42.56.1-2.3-1.9-2.42.2-2.5-2.0-1.02.0-0.91.01.0-1.3-1.0-0.9-0.91.01.1-0.6
Breakpoint value in progressive ratio session0.81.02.1-1.2-1.5-1.11.1-1.0-1.0-0.50.9-1.00.80.9-1.2-0.8-0.9-0.90.81.20.1
Number of licking bursts0.50.81.40.60.90.9-0.00.40.61.1-0.51.1-1.1-1.1-0.11.11.21.2-1.20.51.1
Context. condit. distance diff. score0.20.20.7-0.3-0.1-0.50.5-0.9-0.20.40.10.5-0.5-0.5-0.40.50.40.4-0.30.40.3
Locomotion velocity, session 15.66.09.62.63.12.7-2.12.42.42.6-1.92.5-2.5-2.62.72.62.52.5-2.5-2.31.3
Locomotion distance, session 14.05.17.82.52.82.7-2.02.32.32.3-2.12.3-2.3-2.31.92.42.32.3-2.5-1.31.5
Locomotion velocity, session 24.24.87.71.72.42.0-1.12.11.82.5-0.82.4-2.5-2.52.82.52.42.4-2.5-2.41.7
Locomotion distance, session 23.95.47.32.62.72.7-2.32.52.52.4-2.32.3-2.4-2.41.92.42.32.3-2.3-1.51.8
Locomotion velocity, session 33.74.26.61.72.32.0-1.22.11.82.2-0.82.2-2.2-2.22.62.22.12.1-2.3-2.41.6
Locomotion distance, session 34.04.36.01.52.21.7-0.91.71.72.4-0.82.4-2.4-2.52.42.42.42.4-2.4-2.21.8
Stereotopy head waving bouts, day 31.61.92.7-1.3-1.5-1.31.2-1.5-1.4-1.41.0-1.41.31.3-1.6-1.3-1.4-1.41.41.7-1.0
Stereotopy head waving duration, day 30.50.70.9-0.8-0.8-0.80.7-0.7-0.8-0.90.8-0.90.90.9-0.4-0.9-1.0-1.00.80.4-0.8
Locomotion velocity, session 70.20.20.90.80.70.5-1.00.20.60.2-0.90.2-0.2-0.30.30.20.20.2-0.3-0.2-0.4
Locomotion distance, session 71.31.73.51.61.81.5-1.61.41.31.0-1.31.0-1.0-1.11.91.00.90.9-0.8-1.7-0.1
Stereotopy head waving bouts, day 72.73.05.6-1.3-1.7-1.61.1-2.0-1.6-1.80.8-1.91.81.8-2.3-1.8-1.8-1.81.62.4-1.7
Stereotopy head waving duration, day 72.53.13.7-1.6-1.8-1.81.3-1.9-1.7-1.91.2-1.91.81.9-1.9-1.8-1.8-1.81.61.8-1.7
Locomotion velocity, session 80.10.10.30.10.4-0.0-0.0-0.30.10.5-0.10.4-0.4-0.50.20.40.40.4-0.5-0.1-0.1
Locomotion distance, session 83.55.17.92.12.52.0-1.61.42.12.7-1.82.7-2.8-2.71.82.82.62.6-2.5-1.41.7
Degree of sensitization distance0.91.02.3-0.1-0.6-0.4-0.4-0.5-0.5-1.2-0.3-1.21.21.2-0.8-1.2-1.3-1.31.40.8-1.5
Degree of sensitization stereotypy1.92.03.4-1.2-1.4-1.41.0-1.7-1.3-1.50.8-1.51.41.5-1.9-1.4-1.4-1.41.21.9-1.5
Conditioned locomotion2.12.44.01.31.51.3-1.01.11.41.8-1.31.8-1.9-1.81.01.91.81.8-2.0-0.71.7
Cocaine response after cond. corrected0.91.02.01.41.31.4-1.31.21.20.9-1.41.0-1.0-0.90.51.00.80.8-0.6-0.20.5
Cocaine response after cond. not corrected0.80.91.91.31.11.2-1.41.01.20.8-1.30.9-0.9-0.80.60.80.80.8-0.6-0.40.5
Cocaine response before conditioning0.10.10.3-0.1-0.3-0.3-0.2-0.0-0.0-0.50.2-0.50.50.40.3-0.6-0.4-0.40.3-0.5-0.5
Saline control response0.30.40.90.70.50.6-0.70.60.80.6-0.90.6-0.6-0.60.00.50.70.7-0.90.20.9
Bone: connectivity density0.10.10.8-0.5-0.4-0.60.9-0.4-0.20.00.60.1-0.1-0.10.10.10.10.10.1-0.30.3
Bone: cortical apparent density0.40.62.91.40.81.2-1.30.70.90.1-1.70.1-0.0-0.0-0.6-0.00.10.10.00.9-0.3
Bone: cortical area0.60.91.8-1.3-1.3-1.21.3-1.0-1.0-0.71.0-0.70.70.7-1.0-0.8-0.7-0.70.70.80.2
Bone: cortical porosity0.20.31.80.20.30.1-0.30.40.30.30.00.3-0.4-0.41.20.40.30.3-0.3-1.40.1
Bone: cortical porosity0.40.51.80.40.50.4-0.40.70.60.7-0.20.6-0.7-0.71.20.70.60.6-0.6-1.30.5
Bone: cortical thickness0.20.40.7-0.4-0.6-0.60.2-0.4-0.5-0.70.2-0.70.80.8-0.4-0.8-0.8-0.80.60.3-0.6
Bone: cortical thickness1.41.63.41.51.21.5-1.41.81.51.0-1.31.0-1.0-1.01.71.00.80.8-0.9-1.70.9
Bone: cortical tissue density0.50.73.01.40.91.3-1.30.91.00.3-1.70.3-0.2-0.2-0.40.10.20.2-0.20.8-0.1
Condit. Reinf. active minus inactive responses0.91.01.51.11.01.2-1.01.21.11.0-1.11.0-0.9-1.00.70.91.01.0-1.1-0.51.1
Condit. Reinf. active-inactive response ratio0.60.71.20.80.70.9-0.71.10.90.8-0.70.8-0.7-0.70.70.70.80.8-0.7-0.71.0
Condit. Reinf. active responses2.32.84.11.71.71.8-1.61.81.81.7-1.71.7-1.7-1.71.31.61.71.7-2.0-1.11.6
Condit. Reinf. inactive responses2.12.63.91.81.81.7-1.71.61.71.6-1.71.5-1.6-1.61.41.61.51.5-2.0-1.21.1
Incentive salience index mean0.60.71.10.80.70.8-0.80.60.90.9-1.00.9-0.9-0.90.20.90.90.9-1.1-0.00.9
Condit. Reinf. lever presses0.10.20.90.30.20.1-0.2-0.40.20.4-0.50.4-0.4-0.4-0.70.50.40.4-0.50.90.2
Condit. Reinf. active minus inactive responses1.01.42.2-0.7-1.2-0.80.4-0.9-0.9-1.40.4-1.41.31.3-1.3-1.3-1.5-1.51.51.2-1.1
Condit. Reinf. active-inactive response ratio0.50.61.1-0.6-0.8-0.70.4-0.7-0.7-0.80.4-0.80.80.8-0.8-0.8-0.9-0.91.00.7-0.7
Condit. Reinf. active responses1.31.82.8-0.7-1.2-0.90.4-1.0-1.0-1.70.3-1.61.51.6-1.6-1.5-1.7-1.71.51.6-1.5
Condit. Reinf. inactive responses0.10.10.50.20.00.1-0.4-0.2-0.0-0.4-0.4-0.40.30.3-0.5-0.3-0.4-0.40.00.7-0.7
Condit. Reinf. lever presses0.10.20.70.50.10.5-0.80.80.5-0.2-0.6-0.20.30.20.2-0.3-0.3-0.30.2-0.30.0
Condit. Reinf. lever reinforcers received0.60.81.4-0.2-0.7-0.4-0.1-0.5-0.5-1.1-0.1-1.11.11.1-1.0-1.0-1.2-1.21.01.0-1.1
Conditioned reinforcement - actives0.91.55.70.0-0.7-0.4-0.5-0.6-0.6-1.5-0.3-1.51.51.5-0.6-1.5-1.6-1.61.60.8-2.4
Conditioned reinforcement - inactives0.50.73.60.90.30.2-1.90.10.5-0.5-1.4-0.70.70.70.3-0.7-0.6-0.60.3-0.3-1.6
Conditioned locomotion1.52.06.3-0.5-1.2-1.0-0.1-1.0-1.0-1.70.2-1.71.71.7-0.5-1.6-1.8-1.81.80.5-2.5
Patch foraging indifference point 0 sec1.12.13.21.71.81.7-1.31.11.51.6-1.61.6-1.6-1.60.71.61.41.4-1.5-0.21.0
Patch foraging indifference point AUC0.60.82.31.21.21.2-1.50.50.90.8-1.50.8-0.7-0.7-0.10.60.80.8-0.90.60.2
Delay disc. indifference point, 0s delay0.10.10.3-0.1-0.20.1-0.10.5-0.1-0.50.2-0.40.40.40.3-0.4-0.4-0.40.5-0.5-0.2
Delay disc. indifference point, 16s delay0.20.30.5-0.5-0.7-0.50.1-0.4-0.4-0.70.1-0.50.50.5-0.6-0.5-0.6-0.60.60.4-0.2
Delay disc. indifference point, 2s delay4.95.57.2-1.8-2.2-1.91.6-2.0-2.2-2.51.4-2.62.62.6-2.5-2.6-2.7-2.72.72.4-2.4
Delay disc. indifference point, 24s delay0.10.20.4-0.4-0.7-0.30.4-0.1-0.4-0.60.4-0.40.30.3-0.5-0.3-0.3-0.30.40.40.1
Delay disc. indifference point, 4s delay0.80.81.4-0.9-1.2-0.80.6-0.5-0.9-1.00.7-1.01.01.0-0.8-1.0-1.1-1.11.20.5-0.5
Delay disc. indifference point, 8s delay0.10.10.4-0.4-0.4-0.40.2-0.0-0.3-0.50.5-0.20.20.20.2-0.2-0.2-0.20.4-0.6-0.1
Indifference point function ln k0.71.35.2-1.8-1.5-1.42.3-0.6-1.3-0.72.1-0.70.60.5-0.0-0.5-0.7-0.70.8-0.40.4
Indifference point function log k0.71.35.2-1.8-1.5-1.42.3-0.6-1.3-0.72.1-0.70.60.5-0.0-0.5-0.7-0.70.8-0.40.4
Patch foraging total patch changes 0 sec1.73.14.51.92.12.0-1.41.61.82.0-1.72.0-2.0-2.01.12.01.81.8-1.9-0.71.4
Patch foraging total patch changes 12 sec2.12.76.52.32.02.2-2.41.41.91.4-2.61.4-1.4-1.40.31.41.41.4-1.50.20.9
Patch foraging total patch changes 18 sec2.63.96.92.42.52.2-2.51.12.02.1-2.62.1-2.1-2.00.62.02.02.0-2.30.10.9
Patch foraging total patch changes 24 sec0.91.52.41.31.51.4-1.00.51.11.3-1.51.3-1.3-1.3-0.31.31.41.4-1.50.80.9
Patch foraging total patch changes 6 sec0.50.82.61.51.61.4-1.30.60.80.7-1.30.6-0.6-0.60.30.60.60.6-0.80.2-0.6
Patch foraging time to switch 0 sec0.40.82.8-0.1-0.5-0.4-0.1-0.6-0.4-1.10.0-1.11.11.1-0.4-1.0-1.2-1.21.10.3-1.7
Patch foraging water rate 0 sec0.20.42.4-0.10.20.30.30.40.30.80.00.8-0.8-0.8-0.10.80.80.8-0.90.21.5
Patch foraging water rate 12 sec0.40.93.20.10.40.5-0.01.00.61.10.11.2-1.1-1.20.81.11.21.2-1.2-0.81.8
Patch foraging water rate 18 sec0.00.10.30.20.00.30.10.40.30.2-0.20.2-0.3-0.2-0.00.30.10.1-0.30.10.6
Patch foraging water rate 24 sec0.10.20.7-0.6-0.6-0.40.8-0.5-0.5-0.20.5-0.20.20.2-0.7-0.3-0.1-0.10.10.70.3
Patch foraging water rate 6 sec0.71.15.5-0.6-0.2-0.31.30.10.21.20.81.3-1.2-1.3-0.11.21.21.2-0.9-0.02.4
Seeking ratio, delayed vs. immediate footshock0.20.30.80.2-0.10.2-0.90.80.2-0.7-0.5-0.60.60.60.1-0.6-0.6-0.60.6-0.40.0
Distance traveled before self-admin0.30.41.0-0.5-0.6-0.60.2-0.6-0.6-0.50.4-0.60.70.7-0.1-0.7-0.9-0.91.0-0.0-1.0
Distance traveled after self-admin0.30.41.0-0.3-0.8-0.3-0.20.3-0.1-0.80.3-0.70.70.70.3-0.6-1.0-1.01.0-0.6-0.2
Extensor digitorum longus weight7.529.333.7-5.5-5.8-5.54.8-5.4-5.8-5.74.9-5.85.75.7-5.1-5.7-5.6-5.65.34.5-4.7
Bone: elastic displacement0.81.04.11.01.01.3-1.21.90.90.3-0.60.3-0.2-0.21.90.10.30.3-0.4-2.00.1
Bone: elastic work0.50.74.70.40.50.7-0.51.50.4-0.10.2-0.10.20.11.9-0.2-0.1-0.1-0.0-2.2-0.1
Bone: endosteal estimation1.02.26.7-2.4-1.9-2.22.6-2.0-1.9-0.62.4-0.60.60.5-1.2-0.6-0.5-0.50.60.90.4
Bone: endosteal perimeter1.02.15.9-2.3-1.9-2.02.4-1.8-1.8-0.72.1-0.70.70.6-1.4-0.7-0.6-0.60.81.10.5
Epididymis fat weight1.13.89.91.01.11.6-0.82.81.71.8-0.31.7-1.7-1.72.91.61.91.9-1.6-3.23.0
Delta time in closed arm before/after self-admin0.30.30.9-0.7-0.8-0.50.5-0.4-0.5-0.70.4-0.40.50.5-0.9-0.5-0.5-0.50.40.90.3
Delta time in open arm before/after self-admin2.32.34.51.51.51.4-1.41.61.61.7-1.11.6-1.5-1.52.11.41.31.3-1.3-2.00.9
Diff in mean of infusions in LGA sessions0.10.10.2-0.3-0.4-0.40.0-0.3-0.3-0.20.1-0.40.40.4-0.2-0.3-0.1-0.10.20.1-0.1
Delay discount exponential model param0.91.01.91.01.30.9-0.70.61.01.3-0.91.1-1.1-1.10.71.11.21.2-1.4-0.40.7
Extinction: sum of active levers before priming1.21.35.5-1.9-1.1-1.52.3-1.4-1.60.12.0-0.60.40.5-0.8-0.4-0.5-0.50.30.90.2
Active lever presses in extinction session 60.10.10.4-0.5-0.4-0.20.5-0.2-0.30.20.3-0.00.00.0-0.4-0.0-0.1-0.10.10.50.7
Bone: final force1.11.86.0-2.2-1.6-2.02.4-1.7-1.7-0.62.2-0.60.80.7-0.7-0.8-0.7-0.70.60.3-0.0
Bone: final moment1.52.47.3-2.5-1.9-2.32.7-1.9-2.0-0.92.6-0.90.90.9-0.8-1.0-0.9-0.90.80.4-0.2
Food consumed during 24 hour testing period0.50.71.6-0.00.4-0.00.20.00.41.10.01.1-1.0-1.00.60.91.21.2-1.3-0.61.2
Glucose0.20.31.40.60.60.4-1.20.40.3-0.2-0.70.0-0.2-0.10.80.20.10.1-0.2-0.8-0.6
Heart weight0.40.63.7-0.0-0.20.10.70.40.50.9-0.00.9-0.9-0.90.30.91.01.0-0.8-0.41.9
Delay discount hyperbolic model param1.21.32.41.11.41.0-0.80.71.11.4-1.01.3-1.3-1.30.81.31.41.4-1.6-0.50.9
Intermittent access intake day 1-15 change0.00.10.3-0.00.00.10.30.20.10.10.20.4-0.3-0.30.10.30.30.3-0.2-0.20.6
Intermittent access intake escalation0.00.10.5-0.00.00.20.40.30.10.10.30.4-0.4-0.40.10.40.30.3-0.2-0.20.7
Intermittent access intake escalation 20.10.10.30.10.10.2-0.00.20.20.4-0.00.4-0.4-0.40.30.40.30.3-0.2-0.40.5
Intermitt. access day 1 inactive lever presses0.51.93.2-0.7-1.1-1.20.2-1.4-0.9-1.40.2-1.61.71.7-1.6-1.8-1.6-1.61.41.3-1.8
Intermitt. access day 15 inactive lever presses0.20.30.7-0.2-0.5-0.5-0.1-0.1-0.2-0.90.1-0.70.80.8-0.1-0.9-0.6-0.60.5-0.3-0.7
Intermitt. access escalation Index2.53.57.4-1.2-1.3-1.51.0-2.1-1.7-2.20.9-2.02.02.0-1.9-2.0-2.0-2.02.02.0-2.7
Intermittent access day 1 total infusions0.30.51.40.7-0.00.3-1.20.00.3-0.6-1.1-0.70.60.6-0.6-0.5-0.7-0.70.60.8-1.1
Intermittent access day 15 total infusions0.20.31.60.70.20.4-0.8-0.10.2-0.6-0.8-0.40.40.4-0.4-0.4-0.4-0.40.50.6-1.3
Intermittent access terminal intake (last 3 days)0.71.03.20.5-0.30.0-0.8-0.4-0.1-1.3-0.8-1.11.11.1-1.1-1.1-1.1-1.11.21.2-1.8
Intermittent access total infusions0.91.14.00.3-0.4-0.2-0.7-0.7-0.3-1.1-0.8-1.21.11.1-1.2-1.1-1.1-1.11.21.4-2.0
Intermittent access day 1 locomotion0.50.61.60.1-0.4-0.2-0.4-0.5-0.3-0.5-0.5-1.10.80.9-0.9-0.7-1.0-1.01.01.1-1.3
Intermittent access day 15 total locomotion0.00.10.4-0.3-0.3-0.40.1-0.2-0.2-0.20.3-0.10.10.10.4-0.1-0.1-0.10.0-0.7-0.1
Intermittent access total locomotion0.50.51.8-0.2-0.4-0.6-0.1-0.7-0.5-0.90.0-0.90.90.9-0.6-0.9-0.9-0.90.80.6-1.3
Intermittent access standard deviation0.40.81.81.10.80.9-1.30.71.00.8-1.20.8-0.8-0.80.90.80.80.8-0.5-0.90.2
Left kidney weight0.00.10.4-0.1-0.0-0.10.20.20.10.50.10.4-0.4-0.40.50.30.30.3-0.3-0.60.5
Right kidney weight0.10.51.6-1.1-0.5-1.11.3-0.8-0.9-0.11.2-0.30.40.30.1-0.4-0.4-0.40.1-0.3-0.2
Cocaine induced anxiety1.31.93.4-1.6-1.2-1.51.5-1.2-1.7-1.51.8-1.41.41.4-0.4-1.4-1.4-1.41.40.2-1.5
Post-drug Anxiety0.60.61.9-1.3-1.0-1.01.3-0.6-1.0-0.71.4-0.50.50.5-0.5-0.5-0.5-0.50.50.10.2
Baseline Anxiety1.92.26.01.00.91.1-1.01.21.51.5-1.31.7-1.7-1.70.51.71.71.7-1.7-0.62.4
Tail length0.20.61.50.91.20.9-0.91.00.70.6-0.80.4-0.5-0.51.20.50.60.6-0.8-1.1-0.1
Length with tail0.00.21.20.20.30.4-0.30.70.30.20.00.1-0.0-0.10.9-0.1-0.0-0.0-0.0-1.10.1
Length without tail0.20.71.5-1.0-1.2-0.91.0-0.4-0.8-0.71.2-0.70.90.8-0.0-1.0-1.0-1.01.1-0.4-0.2
Times rat made contact with spout0.40.51.3-0.40.1-0.10.80.00.00.70.80.7-0.8-0.80.50.80.80.8-0.9-0.61.1
Lifetime Intake0.91.03.30.2-0.4-0.2-0.5-0.6-0.3-1.2-0.6-1.21.21.2-1.2-1.1-1.1-1.11.11.4-1.8
Liver weight, left3.25.310.5-3.2-2.9-3.03.2-2.2-2.7-2.13.2-2.02.02.0-1.2-2.0-2.0-2.01.90.7-1.0
Liver weight, right0.30.41.5-0.9-0.9-0.81.2-0.3-0.6-0.61.2-0.50.40.50.3-0.4-0.5-0.50.5-0.6-0.2
Locomotor activity0.20.21.0-0.2-0.1-0.3-0.5-0.3-0.3-0.50.1-0.50.50.50.3-0.5-0.5-0.50.7-0.4-1.0
Locomotor testing distance0.10.10.70.10.30.1-0.5-0.0-0.1-0.30.0-0.20.30.30.5-0.3-0.3-0.30.4-0.5-0.8
Locomotor testing rearing0.10.10.8-0.00.40.2-0.20.4-0.10.10.30.3-0.2-0.20.80.20.20.2-0.3-0.9-0.0
Locomotion in novel chamber4.96.39.4-2.8-2.4-2.62.7-2.2-2.8-3.12.8-2.52.72.7-1.8-2.7-2.5-2.52.51.4-1.9
Locomotion in novel chamber post-restriction1.01.73.6-0.7-0.7-0.90.3-1.1-1.0-1.90.2-1.51.51.5-1.5-1.5-1.5-1.51.11.5-1.6
Fecal boli incidents, locomotor time 12.23.34.01.81.71.9-1.41.91.92.0-1.31.9-1.9-1.91.91.91.81.8-1.7-1.81.6
Change in fecal boli incidents, locomotor task0.80.81.1-1.0-0.7-1.00.8-0.9-1.1-0.90.8-0.90.90.9-0.7-0.9-0.9-0.90.80.6-0.9
Time >=10cm from walls, locomotor time 10.50.61.20.70.70.8-0.51.00.90.7-0.60.7-0.7-0.70.50.70.80.8-0.7-0.71.1
Bouts of movement, locomotor time 11.01.12.51.31.01.2-1.50.91.20.8-1.61.0-1.0-1.00.60.91.01.0-1.0-0.40.6
Total resting periods, locomotor time 11.92.13.01.71.61.7-1.71.51.61.3-1.71.4-1.4-1.41.21.41.41.4-1.5-0.91.1
Rest time, locomotor task time 10.30.40.70.70.80.8-0.50.60.50.6-0.50.6-0.6-0.60.60.60.70.7-0.7-0.50.2
Distance moved, locomotor task time 10.40.61.3-0.5-0.7-0.40.4-0.2-0.5-1.10.3-1.01.01.0-1.1-0.9-0.9-0.90.81.1-0.2
Vertical activity count, locomotor time 10.92.13.6-0.8-1.4-1.20.2-1.4-1.1-1.90.2-1.61.61.6-1.7-1.6-1.6-1.61.71.6-1.7
Time >=10cm from walls, locomotor time 20.00.10.30.20.20.1-0.40.30.1-0.6-0.3-0.20.30.30.0-0.3-0.1-0.10.1-0.2-0.1
Bouts of movement, locomotor time 21.11.83.1-1.2-1.3-1.41.0-1.7-1.4-1.40.7-1.31.31.3-1.7-1.4-1.3-1.31.21.8-1.2
Total resting periods, locomotor time 21.11.83.6-1.1-1.3-1.30.8-1.7-1.3-1.40.5-1.31.41.4-1.8-1.4-1.3-1.31.21.9-1.3
Rest time, locomotor task time 20.50.71.00.91.00.8-0.70.30.80.9-1.01.0-0.9-0.90.40.91.01.0-0.9-0.10.2
Distance moved, locomotor task time 20.10.10.6-0.2-0.10.00.00.5-0.1-0.80.2-0.50.50.5-0.0-0.5-0.4-0.40.3-0.20.1
Vertical activity count, locomotor time 20.81.23.2-0.7-0.9-0.70.5-0.5-0.9-1.80.6-1.31.31.3-0.8-1.3-1.2-1.21.30.7-1.1
Light reinforcement 11.12.75.61.91.91.8-2.00.91.71.7-2.41.7-1.7-1.70.31.81.71.7-1.70.41.0
Light reinforcement 20.91.33.21.71.61.4-1.81.01.31.0-1.61.0-1.0-1.00.90.91.01.0-0.8-0.5-0.1
Bone: marrow area1.02.16.5-2.4-1.9-2.22.6-2.0-1.9-0.62.3-0.60.60.5-1.2-0.6-0.6-0.60.70.90.4
Bone: maximum diameter0.50.81.8-1.2-1.3-1.21.2-1.2-1.0-0.60.8-0.60.60.5-1.3-0.6-0.6-0.60.61.30.1
Bone: maximum force1.22.24.8-2.2-1.7-2.12.1-2.0-1.9-1.02.0-1.01.11.1-1.1-1.2-1.0-1.01.00.9-0.6
Bone: maximum moment1.62.86.2-2.5-1.9-2.32.4-2.2-2.2-1.22.4-1.11.31.2-1.1-1.3-1.2-1.21.10.8-0.7
Mean time between licks in bursts0.10.32.30.20.60.1-0.1-0.1-0.2-0.20.3-0.20.30.30.9-0.3-0.2-0.20.1-0.9-1.5
Mean num. licks in bursts0.30.51.5-0.8-0.8-0.80.4-0.1-0.5-0.61.0-0.60.60.60.7-0.6-0.6-0.60.5-1.2-0.3
Cd content in liver0.30.41.00.1-0.2-0.0-0.60.2-0.2-0.8-0.1-0.80.80.80.1-0.8-0.8-0.80.8-0.2-1.0
Co content in liver0.30.30.6-0.7-0.6-0.60.4-0.6-0.8-0.50.7-0.50.60.6-0.6-0.6-0.5-0.50.70.5-0.4
Cu content in liver3.64.29.9-2.7-2.7-2.53.2-2.3-2.2-1.52.6-1.61.61.5-2.2-1.6-1.6-1.61.61.9-0.1
Fe content in liver0.10.10.3-0.3-0.2-0.10.30.1-0.4-0.30.5-0.20.20.3-0.1-0.3-0.2-0.20.40.1-0.1
K content in liver0.30.20.9-0.8-0.3-0.60.9-0.7-0.70.20.90.2-0.1-0.2-0.40.10.20.2-0.40.50.3
Mg content in liver0.20.21.0-0.8-0.2-0.61.0-0.7-0.60.20.90.2-0.1-0.2-0.20.10.10.1-0.20.20.2
Mn content in liver0.10.11.2-0.10.3-0.3-0.5-0.6-0.3-0.10.00.00.0-0.00.1-0.0-0.2-0.20.3-0.0-1.1
Na content in liver1.11.22.8-1.5-1.0-1.61.1-1.7-1.4-0.81.3-0.90.90.8-0.8-0.9-0.8-0.80.80.6-1.0
Rb content in liver0.50.61.2-1.1-1.0-0.81.1-0.7-1.0-0.61.0-0.60.70.7-0.9-0.7-0.6-0.60.40.90.1
Se content in liver0.30.40.50.60.70.6-0.60.70.60.6-0.50.7-0.7-0.70.70.70.60.6-0.4-0.70.3
Sr content in liver0.50.40.90.00.50.10.10.20.20.70.20.9-0.9-0.90.90.90.70.7-0.7-0.90.4
Zn content in liver1.92.14.41.21.11.3-0.51.21.51.7-1.01.8-1.8-1.70.81.81.61.6-1.6-0.62.1
Bone: minimum diameter1.22.14.2-2.1-2.0-2.02.0-1.8-1.7-1.11.7-1.11.21.2-1.4-1.2-1.2-1.21.11.1-0.2
Time in familiar zone, hab. session 10.10.11.10.10.20.2-0.30.60.20.10.20.1-0.0-0.10.90.00.10.10.1-1.00.1
Time in novel zone, hab. session 10.60.63.1-0.3-0.7-0.50.3-1.0-0.5-0.6-0.2-0.70.60.6-1.6-0.6-0.7-0.70.51.8-0.6
Total zone transitions, hab. session 10.50.72.51.31.00.9-1.30.31.00.7-1.60.6-0.7-0.7-0.30.80.70.7-0.70.60.0
Total locomotion distance, hab. session 13.14.45.52.22.22.2-2.01.82.32.3-2.22.3-2.3-2.31.32.32.32.3-2.2-0.92.0
Locomotion velocity, hab. session 12.53.54.51.82.01.9-1.51.61.92.0-1.62.0-2.1-2.11.42.12.12.1-2.0-1.01.7
Time in familiar zone, hab. session 21.51.63.2-1.6-1.2-1.61.5-1.3-1.5-1.21.8-1.21.31.2-0.2-1.4-1.1-1.11.0-0.2-1.3
Time in novel zone, hab. session 20.40.40.90.80.60.9-0.60.60.70.6-0.90.5-0.6-0.5-0.40.60.50.5-0.50.70.8
Total zone transitions, hab. session 21.52.02.61.51.61.4-1.41.11.51.6-1.51.5-1.5-1.50.91.51.51.5-1.6-0.61.1
Total locomotion distance, hab. session 25.26.910.12.32.52.5-1.72.32.63.0-2.03.0-3.0-3.01.73.03.03.0-3.0-1.33.2
Locomotion velocity, hab. session 25.37.010.32.22.52.5-1.72.42.63.1-1.93.0-3.0-3.01.93.03.13.1-3.0-1.53.2
Novel to familiar place preference ratio0.10.21.00.1-0.10.30.10.20.30.3-0.30.3-0.4-0.3-0.50.40.20.2-0.40.61.0
Novelty place preference0.10.10.70.0-0.10.20.20.20.20.3-0.20.2-0.3-0.3-0.40.40.20.2-0.50.50.8
Time in novel zone, NPP test0.10.10.6-0.1-0.20.10.30.10.10.2-0.00.1-0.2-0.2-0.50.30.10.1-0.30.60.8
Total zone transitions, NPP test3.85.58.42.92.82.7-2.72.12.62.3-2.82.3-2.3-2.31.52.32.32.3-2.3-0.91.3
Total locomotion distance, NPP test8.411.513.73.53.63.5-3.03.23.63.6-3.13.6-3.7-3.72.73.73.63.6-3.6-2.13.1
Locomotion velocity, NPP test9.112.815.53.53.83.7-3.13.33.73.9-3.23.9-3.9-3.92.93.93.93.9-3.9-2.33.4
Intraocular pressure0.40.52.00.2-0.1-0.0-0.8-0.2-0.2-0.9-0.5-1.00.90.9-0.2-0.9-0.8-0.80.60.2-1.4
Delta distance traveled before/after self-admin1.92.06.00.90.91.1-0.81.71.51.3-0.71.5-1.5-1.51.41.51.41.4-1.5-1.62.4
Delta ambulatory time before/after self-admin1.31.65.50.70.50.9-0.71.61.31.1-0.51.3-1.3-1.31.41.31.21.2-1.3-1.62.3
Parametrial fat weight0.51.11.91.00.91.3-0.81.31.10.8-0.81.1-1.1-1.20.61.11.11.1-1.0-0.51.4
Pavlov. Cond. lever latency0.40.54.00.40.40.5-0.71.20.50.00.10.00.10.11.7-0.10.10.10.1-2.0-0.0
Pavlov. Cond. magazine entry latency2.93.75.1-1.5-1.7-1.61.3-2.0-1.9-2.11.1-2.12.12.1-2.1-2.1-2.0-2.02.12.1-2.3
Pavlov. Cond. change in total contacts2.32.55.7-1.4-1.6-1.51.5-1.9-1.5-1.41.0-1.41.41.4-2.3-1.5-1.5-1.51.42.4-1.0
Pavlov. Cond. index score2.73.47.9-1.6-1.8-1.71.6-2.3-1.9-1.71.1-1.61.61.6-2.7-1.6-1.7-1.71.62.8-1.5
Pavlov. Cond. latency score2.22.88.2-1.5-1.7-1.61.6-2.2-1.7-1.40.9-1.31.31.3-2.7-1.3-1.4-1.41.32.9-1.1
Pavlov. Cond. lever contacts0.60.84.2-0.7-0.6-0.80.9-1.5-0.8-0.30.3-0.30.20.2-1.7-0.2-0.4-0.40.32.1-0.4
Pavlov. Cond. magazine entry number1.92.43.61.11.41.2-0.91.51.41.7-0.71.7-1.7-1.71.91.71.61.6-1.7-1.91.7
Pavlov. Cond. intertrial magazine entries1.92.34.31.91.61.9-1.92.11.81.3-1.61.2-1.3-1.31.51.31.21.2-1.2-1.41.1
Pavlov. Cond. lever-magazine prob. diff.2.93.67.8-1.6-1.8-1.81.6-2.4-1.9-1.81.1-1.71.71.7-2.7-1.7-1.7-1.71.72.8-1.7
Pavlov. Cond. response bias1.31.62.6-0.9-1.0-1.10.8-1.5-1.2-1.30.6-1.31.31.3-1.5-1.3-1.3-1.31.21.6-1.6
Pavlov. Cond. lever latency1.01.43.2-1.5-1.1-1.51.6-1.8-1.5-0.91.4-0.80.80.8-1.1-0.7-0.8-0.80.81.0-1.0
Pavlov. Cond. magazine entry latency2.02.44.81.81.71.8-2.02.21.81.2-1.51.1-1.1-1.12.21.11.11.1-1.2-2.10.8
Pavlov. Cond. change in total contacts0.20.41.3-0.0-0.5-0.3-0.3-0.4-0.1-0.7-0.4-0.60.70.7-1.0-0.7-0.7-0.70.71.1-0.5
Pavlov. Cond. index score1.62.14.11.81.51.8-2.02.01.81.2-1.71.1-1.0-1.11.61.01.11.1-1.1-1.41.0
Pavlov. Cond. latency score1.82.34.41.91.61.9-2.02.11.91.3-1.71.2-1.2-1.21.61.11.21.2-1.2-1.41.1
Pavlov. Cond. lever contacts1.62.14.41.71.41.8-1.92.11.81.2-1.71.1-1.1-1.21.51.01.11.1-1.2-1.41.3
Pavlov. Cond. magazine entry number0.81.02.5-1.3-1.0-1.31.4-1.6-1.3-0.71.2-0.70.60.6-1.1-0.6-0.6-0.60.61.1-0.7
Pavlov. Cond. intertrial magazine entries0.20.40.90.20.40.40.10.70.40.70.10.6-0.6-0.70.90.70.60.6-0.6-0.90.9
Pavlov. Cond. lever-magazine prob. diff.1.01.43.11.51.21.5-1.81.71.50.8-1.40.8-0.7-0.71.30.60.80.8-0.8-1.20.6
Pavlov. Cond. response bias0.81.12.81.31.01.3-1.61.71.30.7-1.20.7-0.6-0.71.30.60.60.6-0.7-1.30.7
Time in closed arm before self-admin0.20.21.5-0.20.2-0.60.2-1.1-0.4-0.2-0.0-0.10.30.2-0.5-0.4-0.1-0.10.20.6-1.2
Time in closed arm after self-admin1.92.05.3-0.9-1.2-1.10.7-1.5-1.2-1.50.4-1.31.51.4-2.2-1.5-1.4-1.41.52.3-1.3
Time in open arm before self-admin2.52.74.4-1.3-1.6-1.30.8-1.1-1.5-2.01.0-2.11.91.9-1.6-1.8-2.0-2.01.91.5-1.5
Time in open arm after self-admin0.40.51.50.50.50.4-0.60.70.70.7-0.30.6-0.6-0.61.20.60.50.5-0.6-1.20.5
Bone: periosteal estimation1.42.97.7-2.6-2.3-2.52.8-2.2-2.1-0.92.4-0.90.90.9-1.6-1.0-0.9-0.91.01.20.2
Bone: periosteal perimeter1.52.65.1-2.3-2.2-2.02.2-1.8-1.9-1.21.9-1.31.31.2-1.7-1.3-1.3-1.31.31.50.0
Bone: post-yield work0.71.02.5-1.5-1.1-1.41.6-1.4-1.3-0.61.5-0.60.50.5-0.9-0.5-0.5-0.50.80.7-0.3
Progressive ratio test 1 active lever presses0.50.62.51.41.11.2-1.50.60.8-0.0-1.60.1-0.2-0.2-0.20.30.00.0-0.10.6-0.8
Progressive ratio test 1 breakpoint0.50.72.41.41.11.2-1.50.70.90.1-1.60.2-0.3-0.3-0.10.40.10.1-0.20.5-0.6
Progressive ratio test 1 inactive lever presses0.60.91.60.4-0.60.0-0.9-0.10.0-0.9-0.9-1.21.11.1-1.1-1.0-1.2-1.21.11.2-1.2
Progressive ratio test 2 active lever presses1.21.42.7-0.3-1.2-0.60.0-0.7-0.6-1.6-0.1-1.41.31.3-1.5-1.3-1.4-1.41.41.6-1.2
Progressive ratio test 2 breakpoint1.31.53.0-0.4-1.2-0.60.1-0.8-0.7-1.7-0.0-1.41.31.3-1.7-1.3-1.5-1.51.41.7-1.2
Progressive ratio test 2 inactive lever presses0.71.12.0-0.4-1.1-0.7-0.0-0.6-0.6-1.40.1-1.31.31.3-0.9-1.3-1.4-1.41.20.8-1.2
Incentive Sensitization - Responses1.01.52.9-1.1-1.7-1.11.0-1.0-1.0-1.60.8-1.21.21.2-1.5-1.1-1.2-1.21.31.4-0.5
Incentive Sensitization - Breakpoint1.41.83.4-1.2-1.8-1.31.1-1.2-1.2-1.80.9-1.31.31.3-1.7-1.3-1.4-1.41.41.5-0.6
Sum of active levers in priming session hrs 5-60.30.30.50.1-0.30.1-0.6-0.1-0.1-0.3-0.5-0.70.60.6-0.5-0.6-0.7-0.70.70.6-0.5
Progressive ratio0.20.30.7-0.1-0.40.1-0.20.4-0.3-0.3-0.2-0.60.60.6-0.3-0.6-0.8-0.80.80.4-0.4
Food seeking constrained by brief footshock0.50.62.80.90.10.8-1.30.60.90.4-1.70.2-0.2-0.2-1.00.10.10.1-0.11.40.8
Seeking ratio, punishment vs. effort0.10.10.40.40.20.1-0.6-0.20.40.0-0.60.1-0.1-0.1-0.30.10.20.2-0.30.40.1
Retroperitoneal fat weight1.14.57.12.12.42.1-2.52.62.21.5-1.72.1-2.0-2.02.71.92.12.1-1.7-2.61.4
Reaction time number correct0.10.31.2-0.7-0.3-0.30.70.1-0.6-0.21.1-0.30.10.10.80.0-0.4-0.40.2-1.00.0
Reaction time mean minus median0.10.20.80.50.10.1-0.9-0.30.2-0.3-0.8-0.30.30.2-0.3-0.3-0.4-0.40.50.3-0.8
Reaction time mean minus median AUC0.30.71.90.2-0.3-0.1-0.9-0.5-0.2-0.9-0.7-1.01.00.9-0.7-0.9-1.0-1.01.00.8-1.4
Reaction time num false alarms3.04.26.42.42.32.1-2.41.22.32.2-2.52.1-2.1-2.11.32.12.12.1-2.1-0.91.2
Reaction time num false alarms AUC2.03.16.92.42.11.9-2.61.02.11.6-2.61.6-1.6-1.61.11.61.71.7-1.6-0.70.5
Reaction time trials correct on left0.10.31.2-0.7-0.3-0.30.70.1-0.6-0.21.1-0.30.10.10.80.0-0.4-0.40.2-1.00.0
Reaction time trials on left0.10.21.2-0.6-0.2-0.20.50.2-0.4-0.11.0-0.20.00.10.90.1-0.3-0.30.1-1.10.1
Reaction time mean0.10.10.3-0.1-0.3-0.20.2-0.40.10.2-0.10.2-0.2-0.3-0.50.20.10.10.20.50.5
Reaction time mean AUC0.10.10.3-0.4-0.6-0.50.6-0.6-0.2-0.10.3-0.10.10.1-0.5-0.1-0.2-0.20.50.50.2
Median of all reaction times0.20.21.4-0.2-0.4-0.20.7-0.20.10.40.20.5-0.5-0.5-0.40.50.40.4-0.00.31.2
Reaction time omissions2.02.94.81.91.41.8-1.91.82.21.7-1.91.7-1.7-1.71.41.71.61.6-1.4-1.32.0
Reaction time false alarm rate1.62.36.82.11.71.6-2.20.61.91.4-2.61.4-1.3-1.30.21.21.51.5-1.40.30.4
Reaction time premature initiation rate0.10.20.40.50.30.2-0.50.30.60.3-0.60.4-0.4-0.40.30.40.40.4-0.3-0.40.2
Reaction time premature initiations0.10.11.10.00.1-0.1-0.20.30.20.10.10.2-0.3-0.30.80.30.10.1-0.2-1.00.1
Std. dev. reaction times0.10.10.50.4-0.00.1-0.6-0.20.2-0.3-0.7-0.20.20.2-0.4-0.2-0.3-0.30.50.5-0.4
Reaction time trials completed0.10.21.2-0.6-0.2-0.20.50.2-0.4-0.11.0-0.20.00.10.90.1-0.3-0.30.1-1.10.1
Reaction time trials AUC0.10.31.3-0.7-0.4-0.40.70.1-0.6-0.21.1-0.30.10.20.7-0.0-0.4-0.40.2-0.90.0
Run reversals in cocaine runway, females0.10.10.2-0.3-0.2-0.5-0.2-0.2-0.20.10.1-0.30.30.30.3-0.2-0.2-0.20.1-0.5-0.3
Run reversals in cocaine runway, males0.30.30.8-0.1-0.30.00.10.0-0.3-0.60.2-0.80.90.8-0.3-0.9-0.8-0.80.70.3-0.9
Latency to leave start box in cocaine runway0.20.20.6-0.4-0.3-0.40.3-0.5-0.4-0.70.2-0.40.40.4-0.8-0.4-0.3-0.30.20.7-0.2
Latency to leave start box in cocaine runway, F0.10.10.40.40.30.4-0.30.10.30.3-0.60.2-0.3-0.3-0.50.40.20.2-0.40.60.4
Latency to leave start box in cocaine runway, M1.31.23.0-1.3-1.1-1.41.0-1.3-1.2-1.71.1-0.91.11.1-0.8-1.3-0.9-0.90.80.5-0.9
Std. dev. time between licks in bursts0.81.11.90.81.31.1-0.31.00.71.2-0.31.1-1.1-1.11.41.11.01.0-1.2-1.20.6
Total sessions with >9 infusions0.50.62.10.4-0.2-0.0-0.7-0.30.0-0.9-0.9-0.80.80.8-1.1-0.8-0.9-0.90.51.5-1.0
Short access day 1 total inactive lever presses0.60.81.8-0.1-0.6-0.3-0.2-0.0-0.4-1.1-0.0-1.31.41.3-0.6-1.4-1.2-1.20.90.5-1.3
Short access day 10 total inactive lever presses0.30.81.7-0.6-0.9-0.90.0-0.5-0.5-0.80.2-1.01.21.2-0.8-1.3-1.1-1.11.00.6-0.7
Short access day 1 total infusions0.50.62.4-0.1-0.5-0.3-0.5-0.2-0.2-1.6-0.3-1.01.11.1-0.7-1.1-0.8-0.80.70.8-0.7
Short access day 10 total infusions0.40.61.60.7-0.10.3-0.9-0.20.2-0.6-1.1-0.80.60.6-1.0-0.5-0.7-0.70.51.3-1.1
Short access total infusions0.50.61.70.1-0.3-0.3-0.4-0.5-0.3-1.1-0.4-1.00.90.9-0.9-0.9-0.9-0.90.71.1-1.3
Short access day 1 locomotion0.20.30.6-0.2-0.6-0.4-0.0-0.6-0.4-0.6-0.1-0.70.60.6-0.6-0.5-0.6-0.60.40.7-0.8
Short access day 10 total locomotion0.00.10.30.1-0.0-0.2-0.2-0.40.10.0-0.4-0.20.00.0-0.50.0-0.1-0.10.10.6-0.2
Short access total locomotion0.20.21.10.40.00.1-0.5-0.20.1-0.3-0.6-0.50.30.3-0.7-0.2-0.4-0.40.31.1-0.6
One hour access (0.3 mA shock)3.23.74.7-1.7-2.1-1.91.5-1.9-1.8-2.21.3-2.02.02.0-2.1-2.0-2.1-2.12.01.9-1.8
Compulsive drug intake1.11.34.9-1.1-1.4-1.61.0-2.2-1.0-0.60.4-0.70.70.7-1.7-0.6-0.8-0.80.81.7-0.8
One hour access (shock baseline)1.52.33.7-1.1-1.4-0.90.9-0.4-1.3-1.91.1-1.91.91.9-1.2-1.9-1.9-1.91.91.0-1.4
Social response proportion0.60.72.91.10.70.9-1.71.21.10.4-1.10.3-0.3-0.31.10.30.30.3-0.2-1.20.3
Social responses1.31.73.41.51.51.4-1.81.21.41.1-1.51.2-1.2-1.21.21.31.21.2-1.3-1.00.6
Social time0.70.93.20.90.81.0-1.11.61.00.6-0.70.6-0.6-0.61.60.60.50.5-0.7-1.80.7
Soleus weight0.82.33.3-1.6-1.5-1.71.2-1.3-1.7-1.61.8-1.71.61.6-0.2-1.6-1.7-1.71.7-0.2-1.8
Bone: stiffness1.72.87.5-2.5-1.9-2.42.7-2.7-2.1-0.72.1-0.70.70.7-1.9-0.8-0.7-0.70.81.8-0.2
Tibialis anterior weight5.518.726.1-4.2-4.4-4.43.4-5.0-4.6-4.43.3-4.34.34.3-5.1-4.3-4.1-4.14.15.0-3.9
Time to tail flick, vehicle, before self-admin0.30.30.7-0.1-0.4-0.3-0.2-0.3-0.3-0.6-0.1-0.50.60.6-0.4-0.7-0.7-0.70.80.4-0.8
Time to tail flick, vehicle, after self-admin0.10.20.6-0.7-0.7-0.50.8-0.2-0.50.10.80.0-0.0-0.00.10.00.10.10.1-0.20.4
Time to tail flick, test, before self-admin0.30.32.10.90.70.6-1.50.40.6-0.1-1.10.2-0.1-0.10.30.1-0.1-0.10.1-0.2-0.7
Time to tail flick, test, after self-admin0.91.02.0-1.2-1.0-1.40.9-1.2-1.1-1.21.1-0.81.01.0-0.3-1.1-0.9-0.90.7-0.1-0.9
Delta time to tail flick, vehicle, before/after SA0.60.62.3-0.4-0.30.00.90.2-0.01.00.70.8-0.9-0.90.41.00.90.9-0.7-0.41.5
Delta time to tail flick, test, before/after SA0.40.41.7-1.1-0.8-1.11.3-0.6-0.7-0.41.1-0.20.40.4-0.1-0.5-0.1-0.1-0.1-0.20.4
Tibia length0.20.51.9-1.1-1.1-0.91.4-0.5-0.7-0.31.1-0.40.50.4-0.5-0.5-0.4-0.40.70.30.7
Ambulatory time before self-admin0.30.41.5-0.3-0.4-0.6-0.0-0.6-0.5-0.60.1-0.70.70.8-0.3-0.7-0.9-0.91.00.2-1.2
Ambulatory time after self-admin0.50.51.2-0.6-1.0-0.80.0-0.1-0.4-0.80.5-0.80.80.80.2-0.8-1.1-1.11.0-0.5-0.4
Bone: tissue strength1.81.92.4-1.5-1.4-1.41.1-1.4-1.6-1.41.3-1.41.51.4-1.4-1.5-1.3-1.31.11.3-1.1
Total heroin consumption0.70.82.4-1.4-1.5-1.21.6-1.0-1.1-0.21.3-0.50.40.5-0.7-0.4-0.5-0.50.50.60.4
Bone: trabecular number0.20.30.8-0.6-0.2-0.70.9-0.7-0.30.50.60.6-0.5-0.50.20.40.70.7-0.5-0.40.5
Bone: trabecular spacing0.30.51.8-0.0-0.5-0.2-0.1-0.5-0.3-0.6-0.2-0.70.60.6-1.2-0.6-0.8-0.80.71.3-0.6
Bone: trabecular thickness0.10.10.40.20.40.2-0.30.00.30.4-0.50.5-0.4-0.40.10.40.50.5-0.6-0.00.3
Bone: trabecular tissue density0.40.52.70.80.40.5-1.0-0.30.50.3-1.50.3-0.3-0.3-1.20.20.30.3-0.41.60.0
Water consumed over 24 hours0.20.30.6-0.30.3-0.00.80.1-0.10.50.70.5-0.5-0.50.60.50.60.6-0.7-0.60.6
Number of responses in last shaping day1.61.83.91.61.51.7-1.82.01.50.8-1.20.9-0.9-0.92.00.81.01.0-1.0-1.80.4