Pcbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye alternative TSS XM_063263981.1 0.23 0.14 8.0e-03 0.01 0.02 -0.02 0.02 2.6e-01 1.7e-01 6.9e-01 1.8e-01
2 PL intron excision ratio chr7_135498844_135500312 0.05 0.03 2.4e-04 0.03 0.03 0.03 0.04 1.2e-04 1.2e-04 1.2e-04 3.7e-05
3 NAcc isoform ratio XM_063263998.1 0.01 0.01 6.3e-03 0 0.01 0 0 3.3e-01 1.6e-02 6.3e-02 1.6e-01
4 Eye alternative TSS XM_063263975.1 0.31 0.17 4.0e-03 0 0.03 0.05 0.06 2.9e-01 1.2e-01 5.4e-02 5.2e-02
5 NAcc intron excision ratio chr7_135498844_135500312 0.01 0.01 5.5e-03 0 0.01 0.01 0 2.7e-01 2.1e-02 1.5e-02 1.1e-01
6 Brain mRNA stability Pcbp2 0.02 0.02 7.1e-03 0.01 0.02 0.02 0.02 1.5e-02 4.1e-03 8.2e-03 1.1e-02
7 Brain intron excision ratio chr7_135498844_135500312 0.03 0.03 6.3e-03 0.04 0.02 0.03 0.03 1.8e-04 3.0e-03 1.6e-03 1.1e-03
8 Eye alternative TSS XM_063263975.1 0.31 0.18 3.5e-03 0 0.03 0.06 0.05 2.9e-01 1.2e-01 5.0e-02 5.3e-02
9 Eye gene expression Pcbp2 0.74 0.16 4.2e-04 0.26 0.18 0.24 0.24 6.1e-05 1.1e-03 1.4e-04 1.3e-04
10 Eye intron excision ratio chr7_135486791_135487387 0.82 0.07 6.7e-10 0.51 0.46 0.48 0.52 1.5e-09 2.2e-08 7.9e-09 1.2e-09
11 Eye mRNA stability Pcbp2 0.51 0.17 1.4e-03 0.26 0.18 0.19 0.26 8.0e-05 1.1e-03 8.4e-04 7.8e-05
12 Eye intron excision ratio chr7_135487017_135487387 0.82 0.07 4.0e-10 0.52 0.46 0.47 0.51 1.0e-09 2.1e-08 1.6e-08 1.9e-09
13 IC intron excision ratio chr7_135498844_135500312 0.11 0.08 8.0e-03 0.05 0.02 0.06 0.06 4.6e-03 5.0e-02 2.3e-03 1.9e-03
14 pVTA intron excision ratio chr7_135497657_135498772 0.07 0.06 9.6e-03 0.02 0.01 0 0.01 1.2e-02 7.9e-02 3.1e-01 3.1e-02
15 NAcc intron excision ratio chr7_135497657_135498772 0.03 0.01 3.3e-03 0.02 0.01 0 0.01 7.8e-04 3.2e-02 5.2e-02 6.2e-03
16 pVTA intron excision ratio chr7_135494803_135497616 0.05 0.03 5.0e-04 0.04 0.02 0.03 0.04 2.8e-04 6.8e-03 2.0e-03 8.3e-04
17 Liver isoform ratio XM_063263995.1 0.19 0.12 2.7e-03 0.02 0.01 0.01 0.02 1.0e-03 1.6e-02 1.8e-02 6.6e-03
18 NAcc isoform ratio XM_017595007.3 0.04 0.03 4.0e-03 0.01 0.01 0 0 3.0e-02 2.8e-02 5.9e-02 5.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.61.13.3-1.7-1.3-1.71.81.6-1.30.5-1.60.40.50.50.5-0.60.40.4-0.4-0.3-0.2
Area under the delay curve0.40.71.3-0.8-1.0-0.70.50.4-0.81.1-0.70.90.90.90.9-0.51.01.0-1.1-0.2-0.6
BMI with tail1.34.57.5-2.7-2.6-2.72.72.5-2.41.7-2.21.91.81.81.8-2.31.71.7-1.9-2.0-0.6
BMI without tail0.41.93.3-1.8-1.3-1.71.81.5-1.71.1-1.61.41.31.21.3-1.31.11.1-1.0-1.2-0.7
Body weight0.41.93.7-1.9-1.7-1.81.91.4-1.61.3-1.81.31.31.21.3-0.91.21.2-1.3-0.6-0.5
Weight adjusted by age0.10.41.50.90.61.0-0.9-1.20.8-0.40.7-0.1-0.2-0.2-0.20.5-0.0-0.00.20.40.4
Bone surface1.52.96.6-2.5-2.1-2.62.42.4-2.11.2-2.21.11.21.21.2-1.21.21.2-1.3-0.9-0.8
Bone volume1.22.56.1-2.3-1.9-2.42.22.5-2.01.0-2.00.91.01.01.0-1.30.90.9-1.0-1.1-0.6
Breakpoint value in progressive ratio session0.51.02.1-1.2-1.5-1.11.11.0-1.00.5-0.91.00.80.90.8-1.20.90.9-0.8-1.20.1
Number of licking bursts0.30.81.40.60.90.9-0.0-0.40.6-1.10.5-1.1-1.1-1.1-1.1-0.1-1.2-1.21.2-0.51.1
Context. condit. distance diff. score0.20.20.7-0.3-0.1-0.50.50.9-0.2-0.4-0.1-0.5-0.5-0.5-0.5-0.4-0.4-0.40.3-0.40.3
Locomotion velocity, session 15.46.09.62.63.12.7-2.1-2.42.4-2.61.9-2.5-2.5-2.6-2.62.7-2.5-2.52.52.31.3
Locomotion distance, session 14.05.17.82.52.82.7-2.0-2.32.3-2.32.1-2.3-2.3-2.3-2.41.8-2.3-2.32.51.31.5
Locomotion velocity, session 24.04.87.71.72.42.0-1.1-2.11.8-2.50.8-2.4-2.5-2.5-2.52.8-2.4-2.42.52.41.7
Locomotion distance, session 23.85.47.32.62.72.7-2.3-2.52.5-2.42.3-2.3-2.4-2.4-2.41.9-2.3-2.32.31.51.8
Locomotion velocity, session 33.64.26.61.72.32.0-1.2-2.11.8-2.20.8-2.2-2.2-2.2-2.22.6-2.1-2.12.32.41.6
Locomotion distance, session 33.84.36.01.52.21.7-0.9-1.71.7-2.40.8-2.4-2.4-2.5-2.42.4-2.4-2.42.42.21.8
Stereotopy head waving bouts, day 31.61.92.7-1.3-1.5-1.31.21.5-1.41.4-1.01.41.31.31.3-1.61.41.4-1.4-1.7-1.0
Stereotopy head waving duration, day 30.50.70.9-0.8-0.8-0.80.70.7-0.80.9-0.80.90.90.90.9-0.41.01.0-0.8-0.4-0.8
Locomotion velocity, session 70.20.20.90.80.70.5-1.0-0.20.6-0.20.8-0.2-0.2-0.3-0.20.3-0.2-0.20.30.2-0.4
Locomotion distance, session 71.31.73.41.61.81.5-1.6-1.41.3-1.01.3-1.0-1.0-1.1-1.01.8-0.9-0.90.81.7-0.1
Stereotopy head waving bouts, day 72.63.05.6-1.3-1.7-1.61.12.0-1.61.8-0.81.91.81.81.8-2.31.81.8-1.6-2.4-1.7
Stereotopy head waving duration, day 72.53.13.7-1.6-1.8-1.81.31.9-1.71.9-1.21.91.81.91.8-1.91.81.8-1.6-1.8-1.7
Locomotion velocity, session 80.10.10.30.10.4-0.0-0.00.30.1-0.50.1-0.4-0.4-0.5-0.40.2-0.4-0.40.50.1-0.1
Locomotion distance, session 83.55.17.92.12.52.0-1.6-1.42.1-2.71.8-2.7-2.8-2.7-2.81.8-2.6-2.62.51.41.7
Degree of sensitization distance0.91.02.3-0.1-0.6-0.4-0.40.5-0.51.20.31.21.21.21.2-0.81.31.3-1.4-0.8-1.5
Degree of sensitization stereotypy1.82.03.4-1.2-1.4-1.41.01.7-1.31.5-0.81.51.41.51.4-1.91.41.4-1.2-1.9-1.5
Conditioned locomotion2.02.44.01.31.51.3-1.0-1.11.4-1.81.3-1.8-1.9-1.8-1.91.0-1.8-1.82.00.71.7
Cocaine response after cond. corrected0.71.02.01.41.31.4-1.3-1.21.2-0.91.4-1.0-1.0-0.9-1.00.5-0.8-0.80.60.20.5
Cocaine response after cond. not corrected0.60.91.91.31.11.2-1.4-1.01.2-0.81.3-0.9-0.9-0.8-0.80.6-0.8-0.80.60.40.5
Cocaine response before conditioning0.10.10.3-0.1-0.3-0.3-0.20.0-0.00.5-0.20.50.50.40.60.30.40.4-0.30.5-0.5
Saline control response0.30.40.90.70.50.6-0.7-0.60.8-0.60.9-0.6-0.6-0.6-0.50.0-0.7-0.70.9-0.20.9
Bone: connectivity density0.10.10.8-0.5-0.4-0.60.90.4-0.2-0.0-0.6-0.1-0.1-0.1-0.10.1-0.1-0.1-0.10.30.3
Bone: cortical apparent density0.40.62.91.40.81.2-1.3-0.70.9-0.11.7-0.1-0.0-0.00.0-0.6-0.1-0.1-0.0-0.9-0.3
Bone: cortical area0.50.91.8-1.3-1.3-1.21.31.0-1.00.7-1.00.70.70.70.8-1.00.70.7-0.7-0.80.2
Bone: cortical porosity0.20.31.80.20.30.1-0.3-0.40.3-0.3-0.0-0.3-0.4-0.4-0.41.2-0.3-0.30.31.40.1
Bone: cortical porosity0.40.51.80.40.50.4-0.4-0.70.6-0.70.2-0.6-0.7-0.7-0.71.2-0.6-0.60.61.30.5
Bone: cortical thickness0.20.40.7-0.4-0.6-0.60.20.4-0.50.7-0.20.70.80.80.8-0.40.80.8-0.6-0.3-0.6
Bone: cortical thickness1.31.63.41.51.21.5-1.4-1.81.5-1.01.3-1.0-1.0-1.0-1.01.7-0.8-0.80.91.70.9
Bone: cortical tissue density0.40.73.01.40.91.3-1.3-0.91.0-0.31.7-0.3-0.2-0.2-0.1-0.4-0.2-0.20.2-0.8-0.1
Condit. Reinf. active minus inactive responses0.91.01.51.11.01.2-1.0-1.21.1-1.01.1-1.0-0.9-1.0-0.90.7-1.0-1.01.10.51.1
Condit. Reinf. active-inactive response ratio0.60.71.20.80.70.9-0.7-1.10.9-0.80.7-0.8-0.7-0.7-0.70.7-0.8-0.80.70.71.0
Condit. Reinf. active responses2.22.84.11.71.71.8-1.6-1.81.8-1.71.7-1.7-1.7-1.7-1.61.3-1.7-1.72.01.11.6
Condit. Reinf. inactive responses2.02.63.91.81.81.7-1.7-1.61.7-1.61.7-1.5-1.6-1.6-1.61.4-1.5-1.52.01.21.1
Incentive salience index mean0.50.71.10.80.70.8-0.8-0.60.9-0.91.0-0.9-0.9-0.9-0.90.2-0.9-0.91.10.00.9
Condit. Reinf. lever presses0.10.20.90.30.20.1-0.20.40.2-0.40.5-0.4-0.4-0.4-0.5-0.7-0.4-0.40.5-0.90.2
Condit. Reinf. active minus inactive responses0.91.42.2-0.7-1.2-0.80.40.9-0.91.4-0.41.41.31.31.3-1.31.51.5-1.5-1.2-1.1
Condit. Reinf. active-inactive response ratio0.40.61.1-0.6-0.8-0.70.40.7-0.70.8-0.40.80.80.80.8-0.80.90.9-1.0-0.7-0.7
Condit. Reinf. active responses1.31.82.8-0.7-1.2-0.90.41.0-1.01.7-0.31.61.51.61.5-1.61.71.7-1.5-1.6-1.5
Condit. Reinf. inactive responses0.10.10.50.20.00.1-0.40.2-0.00.40.40.40.30.30.3-0.50.40.4-0.0-0.7-0.7
Condit. Reinf. lever presses0.10.20.70.50.10.5-0.8-0.80.50.20.60.20.30.20.30.20.30.3-0.20.30.0
Condit. Reinf. lever reinforcers received0.60.81.4-0.2-0.7-0.4-0.10.5-0.51.10.11.11.11.11.0-1.01.21.2-1.0-1.0-1.1
Conditioned reinforcement - actives0.41.55.70.0-0.7-0.4-0.50.6-0.61.50.31.51.51.51.5-0.61.61.6-1.6-0.8-2.4
Conditioned reinforcement - inactives0.30.73.60.90.30.2-1.9-0.10.50.51.40.70.70.70.70.30.60.6-0.30.3-1.6
Conditioned locomotion1.32.06.3-0.5-1.2-1.0-0.11.0-1.01.7-0.21.71.71.71.6-0.51.81.8-1.8-0.5-2.5
Patch foraging indifference point 0 sec0.72.13.21.71.81.7-1.3-1.11.5-1.61.6-1.6-1.6-1.6-1.60.6-1.4-1.41.50.21.0
Patch foraging indifference point AUC0.30.82.31.21.21.2-1.5-0.50.9-0.81.5-0.8-0.7-0.7-0.6-0.1-0.8-0.80.9-0.60.2
Delay disc. indifference point, 0s delay0.10.10.3-0.1-0.20.1-0.1-0.5-0.10.5-0.20.40.40.40.40.30.40.4-0.50.5-0.2
Delay disc. indifference point, 16s delay0.20.30.5-0.5-0.7-0.50.10.4-0.40.7-0.10.50.50.50.5-0.60.60.6-0.6-0.4-0.2
Delay disc. indifference point, 2s delay4.95.57.2-1.8-2.2-1.91.62.0-2.22.5-1.42.62.62.62.6-2.52.72.7-2.7-2.4-2.4
Delay disc. indifference point, 24s delay0.10.20.4-0.4-0.7-0.30.40.1-0.40.6-0.40.40.30.30.3-0.50.30.3-0.4-0.40.1
Delay disc. indifference point, 4s delay0.80.81.4-0.9-1.2-0.80.60.5-0.91.0-0.71.01.01.01.0-0.71.11.1-1.2-0.5-0.5
Delay disc. indifference point, 8s delay0.10.10.4-0.4-0.4-0.40.20.0-0.30.5-0.50.20.20.20.20.20.20.2-0.40.6-0.1
Indifference point function ln k0.41.35.2-1.8-1.5-1.42.30.6-1.30.7-2.10.70.60.50.5-0.00.70.7-0.80.40.4
Indifference point function log k0.41.35.2-1.8-1.5-1.42.30.6-1.30.7-2.10.70.60.50.5-0.00.70.7-0.80.40.4
Patch foraging total patch changes 0 sec1.13.14.51.92.12.0-1.4-1.61.8-2.01.7-2.0-2.0-2.0-2.01.1-1.8-1.81.90.71.4
Patch foraging total patch changes 12 sec2.02.76.52.32.02.2-2.4-1.41.9-1.42.6-1.4-1.4-1.4-1.40.3-1.4-1.41.5-0.20.9
Patch foraging total patch changes 18 sec1.73.96.92.42.52.2-2.5-1.12.0-2.12.6-2.1-2.1-2.0-2.00.6-2.0-2.02.3-0.10.9
Patch foraging total patch changes 24 sec0.41.52.41.31.51.4-1.0-0.51.1-1.31.5-1.3-1.3-1.3-1.3-0.3-1.4-1.41.5-0.80.9
Patch foraging total patch changes 6 sec0.50.82.61.51.61.4-1.3-0.60.8-0.71.3-0.6-0.6-0.6-0.60.3-0.6-0.60.8-0.2-0.6
Patch foraging time to switch 0 sec0.20.82.8-0.1-0.5-0.4-0.10.6-0.41.1-0.01.11.11.11.0-0.41.21.2-1.1-0.3-1.7
Patch foraging water rate 0 sec0.10.42.4-0.10.20.30.3-0.40.3-0.8-0.0-0.8-0.8-0.8-0.8-0.1-0.8-0.80.9-0.21.5
Patch foraging water rate 12 sec0.20.93.20.10.40.5-0.0-1.00.6-1.1-0.1-1.2-1.1-1.2-1.10.8-1.2-1.21.20.81.8
Patch foraging water rate 18 sec0.00.10.30.20.00.30.1-0.40.3-0.20.2-0.2-0.3-0.2-0.3-0.0-0.1-0.10.3-0.10.6
Patch foraging water rate 24 sec0.10.20.7-0.6-0.6-0.40.80.5-0.50.2-0.50.20.20.20.3-0.70.10.1-0.1-0.70.3
Patch foraging water rate 6 sec0.71.15.5-0.6-0.2-0.31.3-0.10.2-1.2-0.8-1.3-1.2-1.3-1.2-0.0-1.2-1.20.90.02.4
Seeking ratio, delayed vs. immediate footshock0.20.30.80.2-0.10.2-0.9-0.80.20.70.50.60.60.60.60.10.60.6-0.60.40.0
Distance traveled before self-admin0.20.41.0-0.5-0.6-0.60.20.6-0.60.5-0.40.60.70.70.7-0.00.90.9-1.00.0-1.0
Distance traveled after self-admin0.20.41.0-0.3-0.8-0.3-0.2-0.3-0.10.8-0.30.70.70.70.60.31.01.0-1.00.6-0.2
Extensor digitorum longus weight7.329.333.7-5.5-5.8-5.54.85.4-5.85.7-4.95.85.75.75.7-5.15.65.6-5.3-4.5-4.7
Bone: elastic displacement0.81.04.11.01.01.3-1.2-1.90.9-0.30.6-0.3-0.2-0.2-0.11.9-0.3-0.30.42.00.1
Bone: elastic work0.50.74.70.40.50.7-0.5-1.50.40.1-0.20.10.20.10.21.90.10.10.02.2-0.1
Bone: endosteal estimation0.92.26.7-2.4-1.9-2.22.62.0-1.90.6-2.40.60.60.50.6-1.20.50.5-0.6-0.90.4
Bone: endosteal perimeter0.82.15.9-2.3-1.9-2.02.41.8-1.80.7-2.10.70.70.60.7-1.40.60.6-0.8-1.10.5
Epididymis fat weight0.83.89.91.01.11.6-0.8-2.81.7-1.80.3-1.7-1.7-1.7-1.62.9-1.9-1.91.63.23.0
Delta time in closed arm before/after self-admin0.30.30.9-0.7-0.8-0.50.50.4-0.50.7-0.40.40.50.50.5-0.90.50.5-0.4-0.90.3
Delta time in open arm before/after self-admin1.92.34.51.51.51.4-1.4-1.61.6-1.71.1-1.6-1.5-1.5-1.42.1-1.3-1.31.32.00.9
Diff in mean of infusions in LGA sessions0.00.10.2-0.3-0.4-0.40.00.3-0.30.2-0.10.40.40.40.3-0.20.10.1-0.2-0.1-0.1
Delay discount exponential model param0.81.01.91.01.30.9-0.7-0.61.0-1.30.9-1.1-1.1-1.1-1.10.7-1.2-1.21.40.40.7
Extinction: sum of active levers before priming0.91.35.5-1.9-1.1-1.52.31.4-1.6-0.1-2.00.60.40.50.4-0.80.50.5-0.3-0.90.2
Active lever presses in extinction session 60.10.10.4-0.5-0.4-0.20.50.2-0.3-0.2-0.30.00.00.00.0-0.40.10.1-0.1-0.50.7
Bone: final force1.11.86.0-2.2-1.6-2.02.41.7-1.70.6-2.20.60.80.70.8-0.70.70.7-0.6-0.3-0.0
Bone: final moment1.52.47.3-2.5-1.9-2.32.71.9-2.00.9-2.60.90.90.91.0-0.70.90.9-0.8-0.4-0.2
Food consumed during 24 hour testing period0.30.71.6-0.00.4-0.00.2-0.00.4-1.1-0.0-1.1-1.0-1.0-0.90.6-1.2-1.21.30.61.2
Glucose0.20.31.40.60.60.4-1.2-0.40.30.20.7-0.0-0.2-0.1-0.20.8-0.1-0.10.20.8-0.6
Heart weight0.40.63.7-0.0-0.20.10.7-0.40.5-0.90.0-0.9-0.9-0.9-0.90.3-1.0-1.00.80.41.9
Delay discount hyperbolic model param1.01.32.41.11.41.0-0.8-0.71.1-1.41.0-1.3-1.3-1.3-1.30.8-1.4-1.41.60.50.9
Intermittent access intake day 1-15 change0.00.10.3-0.00.00.10.3-0.20.1-0.1-0.2-0.4-0.3-0.3-0.30.1-0.3-0.30.20.20.6
Intermittent access intake escalation0.00.10.5-0.00.00.20.4-0.30.1-0.1-0.3-0.4-0.4-0.4-0.40.1-0.3-0.30.20.20.7
Intermittent access intake escalation 20.10.10.30.10.10.2-0.0-0.20.2-0.40.0-0.4-0.4-0.4-0.40.3-0.3-0.30.20.40.5
Intermitt. access day 1 inactive lever presses0.21.93.2-0.7-1.1-1.20.21.4-0.91.4-0.21.61.71.71.8-1.61.61.6-1.4-1.3-1.8
Intermitt. access day 15 inactive lever presses0.10.30.7-0.2-0.5-0.5-0.10.1-0.20.9-0.10.70.80.80.9-0.10.60.6-0.50.3-0.7
Intermitt. access escalation Index1.13.57.4-1.2-1.3-1.51.02.1-1.72.2-0.92.02.02.02.0-1.92.02.0-2.0-2.0-2.7
Intermittent access day 1 total infusions0.20.51.40.7-0.00.3-1.2-0.00.30.61.10.70.60.60.5-0.60.70.7-0.6-0.8-1.1
Intermittent access day 15 total infusions0.10.31.60.70.20.4-0.80.10.20.60.80.40.40.40.4-0.50.40.4-0.5-0.6-1.3
Intermittent access terminal intake (last 3 days)0.61.03.20.5-0.30.0-0.80.4-0.11.30.81.11.11.11.1-1.11.11.1-1.2-1.2-1.8
Intermittent access total infusions0.91.14.00.3-0.4-0.2-0.70.7-0.31.10.81.21.11.11.1-1.21.11.1-1.2-1.4-2.0
Intermittent access day 1 locomotion0.30.61.60.1-0.4-0.2-0.40.5-0.30.50.51.10.80.90.7-0.91.01.0-1.0-1.1-1.3
Intermittent access day 15 total locomotion0.00.10.4-0.3-0.3-0.40.10.2-0.20.2-0.30.10.10.10.10.40.10.1-0.00.7-0.1
Intermittent access total locomotion0.50.51.8-0.2-0.4-0.6-0.10.7-0.50.9-0.00.90.90.90.9-0.60.90.9-0.8-0.6-1.3
Intermittent access standard deviation0.10.81.81.10.80.9-1.3-0.71.0-0.81.2-0.8-0.8-0.8-0.80.9-0.8-0.80.50.90.2
Left kidney weight0.00.10.4-0.1-0.0-0.10.2-0.20.1-0.5-0.1-0.4-0.4-0.4-0.30.5-0.3-0.30.30.60.5
Right kidney weight0.10.51.6-1.1-0.5-1.11.30.8-0.90.1-1.20.30.40.30.40.10.40.4-0.10.3-0.2
Cocaine induced anxiety0.71.93.4-1.6-1.2-1.51.51.2-1.71.5-1.81.41.41.41.4-0.41.41.4-1.4-0.2-1.5
Post-drug Anxiety0.60.61.9-1.3-1.0-1.01.30.6-1.00.7-1.40.50.50.50.5-0.50.50.5-0.5-0.10.2
Baseline Anxiety1.32.26.01.00.91.1-1.0-1.21.5-1.51.3-1.7-1.7-1.7-1.70.5-1.7-1.71.70.62.4
Tail length0.10.61.50.91.20.9-0.9-1.00.7-0.60.8-0.4-0.5-0.5-0.51.2-0.6-0.60.81.1-0.1
Length with tail0.00.21.20.20.30.4-0.3-0.70.3-0.2-0.0-0.1-0.0-0.10.10.90.00.00.01.10.1
Length without tail0.10.71.5-1.0-1.2-0.91.00.4-0.80.7-1.20.70.90.81.0-0.01.01.0-1.10.4-0.2
Times rat made contact with spout0.40.51.3-0.40.1-0.10.8-0.00.0-0.7-0.8-0.7-0.8-0.8-0.80.6-0.8-0.80.90.61.1
Lifetime Intake0.81.03.30.2-0.4-0.2-0.50.6-0.31.20.61.21.21.21.1-1.21.11.1-1.1-1.4-1.8
Liver weight, left3.15.310.5-3.2-2.9-3.03.22.2-2.72.1-3.22.02.02.02.0-1.22.02.0-1.9-0.7-1.0
Liver weight, right0.30.41.5-0.9-0.9-0.81.20.3-0.60.6-1.20.50.40.50.40.30.50.5-0.50.6-0.2
Locomotor activity0.20.21.0-0.2-0.1-0.3-0.50.3-0.30.5-0.10.50.50.50.50.30.50.5-0.70.4-1.0
Locomotor testing distance0.00.10.70.10.30.1-0.50.0-0.10.3-0.00.20.30.30.30.50.30.3-0.40.5-0.8
Locomotor testing rearing0.00.10.8-0.00.40.2-0.2-0.4-0.1-0.1-0.3-0.3-0.2-0.2-0.20.8-0.2-0.20.30.9-0.0
Locomotion in novel chamber4.76.39.4-2.8-2.4-2.62.72.2-2.83.1-2.82.52.72.72.7-1.82.52.5-2.5-1.4-1.9
Locomotion in novel chamber post-restriction0.61.73.6-0.7-0.7-0.90.31.1-1.01.9-0.21.51.51.51.5-1.51.51.5-1.1-1.5-1.6
Fecal boli incidents, locomotor time 11.23.34.01.81.71.9-1.4-1.91.9-2.01.3-1.9-1.9-1.9-1.91.9-1.8-1.81.71.81.6
Change in fecal boli incidents, locomotor task0.70.81.1-1.0-0.7-1.00.80.9-1.10.9-0.80.90.90.90.9-0.70.90.9-0.8-0.6-0.9
Time >=10cm from walls, locomotor time 10.50.61.20.70.70.8-0.5-1.00.9-0.70.6-0.7-0.7-0.7-0.70.5-0.8-0.80.70.71.1
Bouts of movement, locomotor time 10.81.12.51.31.01.2-1.5-0.91.2-0.81.6-1.0-1.0-1.0-0.90.6-1.0-1.01.00.40.6
Total resting periods, locomotor time 11.92.13.01.71.61.7-1.7-1.51.6-1.31.7-1.4-1.4-1.4-1.41.2-1.4-1.41.50.91.1
Rest time, locomotor task time 10.20.40.70.70.80.8-0.5-0.60.5-0.60.5-0.6-0.6-0.6-0.60.6-0.7-0.70.70.50.2
Distance moved, locomotor task time 10.20.61.3-0.5-0.7-0.40.40.2-0.51.1-0.31.01.01.00.9-1.10.90.9-0.8-1.1-0.2
Vertical activity count, locomotor time 10.32.13.6-0.8-1.4-1.20.21.4-1.11.9-0.21.61.61.61.6-1.71.61.6-1.7-1.6-1.7
Time >=10cm from walls, locomotor time 20.00.10.30.20.20.1-0.4-0.30.10.60.30.20.30.30.30.00.10.1-0.10.2-0.1
Bouts of movement, locomotor time 20.51.83.1-1.2-1.3-1.41.01.7-1.41.4-0.71.31.31.31.4-1.71.31.3-1.2-1.8-1.2
Total resting periods, locomotor time 20.51.83.6-1.1-1.3-1.30.81.7-1.31.4-0.51.31.41.41.4-1.81.31.3-1.2-1.9-1.3
Rest time, locomotor task time 20.40.71.00.91.00.8-0.7-0.30.8-0.91.0-1.0-0.9-0.9-0.90.3-1.0-1.00.90.10.2
Distance moved, locomotor task time 20.10.10.6-0.2-0.10.00.0-0.5-0.10.8-0.20.50.50.50.5-0.00.40.4-0.30.20.1
Vertical activity count, locomotor time 20.51.23.2-0.7-0.9-0.70.50.5-0.91.8-0.61.31.31.31.3-0.81.21.2-1.3-0.7-1.1
Light reinforcement 10.62.75.61.91.91.8-2.0-0.91.7-1.72.4-1.7-1.7-1.7-1.80.3-1.7-1.71.7-0.41.0
Light reinforcement 20.61.33.21.71.61.4-1.8-1.01.3-1.01.6-1.0-1.0-1.0-0.90.8-1.0-1.00.80.5-0.1
Bone: marrow area0.92.16.5-2.4-1.9-2.22.62.0-1.90.6-2.30.60.60.50.6-1.20.60.6-0.7-0.90.4
Bone: maximum diameter0.40.81.8-1.2-1.3-1.21.21.2-1.00.6-0.80.60.60.50.6-1.30.60.6-0.6-1.30.1
Bone: maximum force1.12.24.8-2.2-1.7-2.12.12.0-1.91.0-2.01.01.11.11.2-1.11.01.0-1.0-0.9-0.6
Bone: maximum moment1.52.86.2-2.5-1.9-2.32.42.2-2.21.2-2.41.11.31.21.3-1.11.21.2-1.1-0.8-0.7
Mean time between licks in bursts0.00.32.30.20.60.1-0.10.1-0.20.2-0.30.20.30.30.30.90.20.2-0.10.9-1.5
Mean num. licks in bursts0.20.51.5-0.8-0.8-0.80.40.1-0.50.6-1.00.60.60.60.60.80.60.6-0.51.2-0.3
Cd content in liver0.30.41.00.1-0.2-0.0-0.6-0.2-0.20.80.10.80.80.80.80.10.80.8-0.80.2-1.0
Co content in liver0.30.30.6-0.7-0.6-0.60.40.6-0.80.5-0.70.50.60.60.6-0.60.50.5-0.7-0.5-0.4
Cu content in liver3.54.29.9-2.7-2.7-2.53.22.3-2.21.5-2.61.61.61.51.6-2.21.61.6-1.6-1.9-0.1
Fe content in liver0.10.10.3-0.3-0.2-0.10.3-0.1-0.40.3-0.50.20.20.30.3-0.10.20.2-0.4-0.1-0.1
K content in liver0.30.20.9-0.8-0.3-0.60.90.7-0.7-0.2-0.9-0.2-0.1-0.2-0.1-0.4-0.2-0.20.4-0.50.3
Mg content in liver0.20.21.0-0.8-0.2-0.61.00.7-0.6-0.2-0.9-0.2-0.1-0.2-0.1-0.2-0.1-0.10.2-0.20.2
Mn content in liver0.10.11.2-0.10.3-0.3-0.50.6-0.30.1-0.0-0.00.0-0.00.00.10.20.2-0.30.0-1.1
Na content in liver1.11.22.8-1.5-1.0-1.61.11.7-1.40.8-1.30.90.90.80.9-0.80.80.8-0.8-0.6-1.0
Rb content in liver0.50.61.2-1.1-1.0-0.81.10.7-1.00.6-1.00.60.70.70.7-0.90.60.6-0.4-0.90.1
Se content in liver0.30.40.50.60.70.6-0.6-0.70.6-0.60.5-0.7-0.7-0.7-0.70.7-0.6-0.60.40.70.3
Sr content in liver0.50.40.90.00.50.10.1-0.20.2-0.7-0.2-0.9-0.9-0.9-0.90.9-0.7-0.70.70.90.4
Zn content in liver1.82.14.41.21.11.3-0.5-1.21.5-1.71.0-1.8-1.8-1.7-1.80.8-1.6-1.61.60.62.1
Bone: minimum diameter1.12.14.2-2.1-2.0-2.02.01.8-1.71.1-1.71.11.21.21.2-1.41.21.2-1.1-1.1-0.2
Time in familiar zone, hab. session 10.10.11.10.10.20.2-0.3-0.60.2-0.1-0.2-0.1-0.0-0.1-0.00.9-0.1-0.1-0.11.00.1
Time in novel zone, hab. session 10.60.63.1-0.3-0.7-0.50.31.0-0.50.60.20.70.60.60.6-1.60.70.7-0.5-1.8-0.6
Total zone transitions, hab. session 10.50.72.51.31.00.9-1.3-0.31.0-0.71.6-0.6-0.7-0.7-0.8-0.3-0.7-0.70.7-0.60.0
Total locomotion distance, hab. session 13.14.45.52.22.22.2-2.0-1.82.3-2.32.2-2.3-2.3-2.3-2.31.3-2.3-2.32.20.92.0
Locomotion velocity, hab. session 12.43.54.51.82.01.9-1.5-1.61.9-2.01.6-2.0-2.1-2.1-2.11.4-2.1-2.12.01.01.7
Time in familiar zone, hab. session 21.41.63.2-1.6-1.2-1.61.51.3-1.51.2-1.81.21.31.21.4-0.21.11.1-1.00.2-1.3
Time in novel zone, hab. session 20.40.40.90.80.60.9-0.6-0.60.7-0.60.9-0.5-0.6-0.5-0.6-0.4-0.5-0.50.5-0.70.8
Total zone transitions, hab. session 21.52.02.61.51.61.4-1.4-1.11.5-1.61.5-1.5-1.5-1.5-1.50.9-1.5-1.51.60.61.1
Total locomotion distance, hab. session 25.26.810.12.32.52.5-1.7-2.32.6-3.02.0-3.0-3.0-3.0-3.01.7-3.0-3.03.01.33.2
Locomotion velocity, hab. session 25.37.010.32.22.52.5-1.7-2.42.6-3.11.9-3.0-3.0-3.0-3.01.9-3.1-3.13.01.53.2
Novel to familiar place preference ratio0.10.21.00.1-0.10.30.1-0.20.3-0.30.3-0.3-0.4-0.3-0.4-0.5-0.2-0.20.4-0.61.0
Novelty place preference0.10.10.70.0-0.10.20.2-0.20.2-0.30.2-0.2-0.3-0.3-0.4-0.4-0.2-0.20.5-0.50.8
Time in novel zone, NPP test0.10.10.6-0.1-0.20.10.3-0.10.1-0.20.0-0.1-0.2-0.2-0.3-0.5-0.1-0.10.3-0.60.8
Total zone transitions, NPP test3.75.58.42.92.82.7-2.7-2.12.6-2.32.8-2.3-2.3-2.3-2.31.5-2.3-2.32.30.91.3
Total locomotion distance, NPP test8.211.413.73.53.63.5-3.0-3.23.6-3.63.1-3.6-3.7-3.7-3.72.7-3.6-3.63.62.13.1
Locomotion velocity, NPP test9.012.815.53.53.83.7-3.1-3.33.7-3.93.2-3.9-3.9-3.9-3.92.9-3.9-3.93.92.33.4
Intraocular pressure0.30.52.00.2-0.1-0.0-0.80.2-0.20.90.41.00.90.90.9-0.20.80.8-0.6-0.2-1.4
Delta distance traveled before/after self-admin1.82.06.00.90.91.1-0.8-1.71.5-1.30.7-1.5-1.5-1.5-1.51.4-1.4-1.41.51.62.4
Delta ambulatory time before/after self-admin0.91.65.50.70.50.9-0.7-1.61.3-1.10.5-1.3-1.3-1.3-1.31.4-1.2-1.21.31.62.3
Parametrial fat weight0.51.11.91.00.91.3-0.8-1.31.1-0.80.8-1.1-1.1-1.2-1.10.6-1.1-1.11.00.51.4
Pavlov. Cond. lever latency0.40.54.00.40.40.5-0.7-1.20.5-0.0-0.1-0.00.10.10.11.7-0.1-0.1-0.12.0-0.0
Pavlov. Cond. magazine entry latency2.93.75.1-1.5-1.7-1.61.32.0-1.92.1-1.12.12.12.12.1-2.12.02.0-2.1-2.1-2.3
Pavlov. Cond. change in total contacts2.32.55.7-1.4-1.6-1.51.51.9-1.51.4-1.01.41.41.41.5-2.31.51.5-1.4-2.4-1.0
Pavlov. Cond. index score2.73.47.9-1.6-1.8-1.71.62.3-1.91.7-1.11.61.61.61.6-2.71.71.7-1.6-2.8-1.5
Pavlov. Cond. latency score2.22.88.2-1.5-1.7-1.61.62.2-1.71.4-0.91.31.31.31.3-2.71.41.4-1.3-2.9-1.1
Pavlov. Cond. lever contacts0.60.84.2-0.7-0.6-0.80.91.5-0.80.3-0.30.30.20.20.2-1.70.40.4-0.3-2.1-0.4
Pavlov. Cond. magazine entry number1.92.43.61.11.41.2-0.9-1.51.4-1.70.7-1.7-1.7-1.7-1.71.9-1.6-1.61.71.91.7
Pavlov. Cond. intertrial magazine entries1.92.34.31.91.61.9-1.9-2.11.8-1.31.6-1.2-1.3-1.3-1.31.5-1.2-1.21.21.41.1
Pavlov. Cond. lever-magazine prob. diff.2.93.67.8-1.6-1.8-1.81.62.4-1.91.8-1.11.71.71.71.7-2.71.71.7-1.7-2.8-1.7
Pavlov. Cond. response bias1.31.62.6-0.9-1.0-1.10.81.5-1.21.3-0.61.31.31.31.3-1.51.31.3-1.2-1.6-1.6
Pavlov. Cond. lever latency1.01.43.2-1.5-1.1-1.51.61.8-1.50.9-1.40.80.80.80.7-1.10.80.8-0.8-1.0-1.0
Pavlov. Cond. magazine entry latency1.72.44.81.81.71.8-2.0-2.21.8-1.21.5-1.1-1.1-1.1-1.12.2-1.1-1.11.22.10.8
Pavlov. Cond. change in total contacts0.20.41.3-0.0-0.5-0.3-0.30.4-0.10.70.40.60.70.70.7-1.00.70.7-0.7-1.1-0.5
Pavlov. Cond. index score1.32.14.11.81.51.8-2.0-2.01.8-1.21.7-1.1-1.0-1.1-1.01.6-1.1-1.11.11.41.0
Pavlov. Cond. latency score1.52.34.41.91.61.9-2.0-2.11.9-1.31.7-1.2-1.2-1.2-1.11.6-1.2-1.21.21.41.1
Pavlov. Cond. lever contacts1.42.14.41.71.41.8-1.9-2.11.8-1.21.7-1.1-1.1-1.2-1.01.5-1.1-1.11.21.41.3
Pavlov. Cond. magazine entry number0.81.02.5-1.3-1.0-1.31.41.6-1.30.7-1.20.70.60.60.6-1.10.60.6-0.6-1.1-0.7
Pavlov. Cond. intertrial magazine entries0.20.40.90.20.40.40.1-0.70.4-0.7-0.1-0.6-0.6-0.7-0.70.9-0.6-0.60.60.90.9
Pavlov. Cond. lever-magazine prob. diff.0.91.43.11.51.21.5-1.8-1.71.5-0.81.4-0.8-0.7-0.7-0.61.3-0.8-0.80.81.20.6
Pavlov. Cond. response bias0.81.12.81.31.01.3-1.6-1.71.3-0.71.2-0.7-0.6-0.7-0.61.3-0.6-0.60.71.30.7
Time in closed arm before self-admin0.10.21.5-0.20.2-0.60.21.1-0.40.20.00.10.30.20.4-0.50.10.1-0.2-0.6-1.2
Time in closed arm after self-admin1.82.05.3-0.9-1.2-1.10.71.5-1.21.5-0.41.31.51.41.5-2.21.41.4-1.5-2.3-1.3
Time in open arm before self-admin2.22.74.4-1.3-1.6-1.30.81.1-1.52.0-1.02.11.91.91.8-1.62.02.0-1.9-1.5-1.5
Time in open arm after self-admin0.40.51.50.50.50.4-0.6-0.70.7-0.70.3-0.6-0.6-0.6-0.61.2-0.5-0.50.61.20.5
Bone: periosteal estimation1.22.97.7-2.6-2.3-2.52.82.2-2.10.9-2.40.90.90.91.0-1.50.90.9-1.0-1.20.2
Bone: periosteal perimeter1.32.65.1-2.3-2.2-2.02.21.8-1.91.2-1.91.31.31.21.3-1.71.31.3-1.3-1.50.0
Bone: post-yield work0.61.02.5-1.5-1.1-1.41.61.4-1.30.6-1.50.60.50.50.5-0.80.50.5-0.8-0.7-0.3
Progressive ratio test 1 active lever presses0.40.62.51.41.11.2-1.5-0.60.80.01.6-0.1-0.2-0.2-0.3-0.2-0.0-0.00.1-0.6-0.8
Progressive ratio test 1 breakpoint0.40.72.41.41.11.2-1.5-0.70.9-0.11.6-0.2-0.3-0.3-0.4-0.1-0.1-0.10.2-0.5-0.6
Progressive ratio test 1 inactive lever presses0.30.91.60.4-0.60.0-0.90.10.00.90.91.21.11.11.0-1.11.21.2-1.1-1.2-1.2
Progressive ratio test 2 active lever presses1.01.42.7-0.3-1.2-0.60.00.7-0.61.60.11.41.31.31.3-1.51.41.4-1.4-1.6-1.2
Progressive ratio test 2 breakpoint1.21.53.0-0.4-1.2-0.60.10.8-0.71.70.01.41.31.31.3-1.71.51.5-1.4-1.7-1.2
Progressive ratio test 2 inactive lever presses0.31.12.0-0.4-1.1-0.7-0.00.6-0.61.4-0.11.31.31.31.3-0.91.41.4-1.2-0.8-1.2
Incentive Sensitization - Responses0.51.52.9-1.1-1.7-1.11.01.0-1.01.6-0.81.21.21.21.1-1.51.21.2-1.3-1.4-0.5
Incentive Sensitization - Breakpoint0.81.83.4-1.2-1.8-1.31.11.2-1.21.8-0.91.31.31.31.3-1.71.41.4-1.4-1.5-0.6
Sum of active levers in priming session hrs 5-60.30.30.50.1-0.30.1-0.60.1-0.10.30.50.70.60.60.6-0.50.70.7-0.7-0.6-0.5
Progressive ratio0.10.30.7-0.1-0.40.1-0.2-0.4-0.30.30.20.60.60.60.6-0.30.80.8-0.8-0.4-0.4
Food seeking constrained by brief footshock0.50.62.80.90.10.8-1.3-0.60.9-0.41.7-0.2-0.2-0.2-0.1-1.1-0.1-0.10.1-1.40.8
Seeking ratio, punishment vs. effort0.00.10.40.40.20.1-0.60.20.4-0.00.6-0.1-0.1-0.1-0.1-0.3-0.2-0.20.3-0.40.1
Retroperitoneal fat weight1.04.57.12.12.42.1-2.5-2.62.2-1.51.7-2.1-2.0-2.0-1.92.7-2.1-2.11.72.61.4
Reaction time number correct0.10.31.2-0.7-0.3-0.30.7-0.1-0.60.2-1.10.30.10.1-0.00.80.40.4-0.21.00.0
Reaction time mean minus median0.00.20.80.50.10.1-0.90.30.20.30.80.30.30.20.3-0.30.40.4-0.5-0.3-0.8
Reaction time mean minus median AUC0.10.71.90.2-0.3-0.1-0.90.5-0.20.90.71.01.00.90.9-0.71.01.0-1.0-0.8-1.4
Reaction time num false alarms2.44.26.42.42.32.1-2.4-1.22.3-2.22.5-2.1-2.1-2.1-2.11.3-2.1-2.12.10.91.2
Reaction time num false alarms AUC1.43.16.92.42.11.9-2.6-1.02.1-1.62.6-1.6-1.6-1.6-1.61.1-1.7-1.71.60.70.5
Reaction time trials correct on left0.10.31.2-0.7-0.3-0.30.7-0.1-0.60.2-1.10.30.10.1-0.00.80.40.4-0.21.00.0
Reaction time trials on left0.10.21.2-0.6-0.2-0.20.5-0.2-0.40.1-1.00.20.00.1-0.10.90.30.3-0.11.10.1
Reaction time mean0.00.10.3-0.1-0.3-0.20.20.40.1-0.20.1-0.2-0.2-0.3-0.2-0.5-0.1-0.1-0.2-0.50.5
Reaction time mean AUC0.10.10.3-0.4-0.6-0.50.60.6-0.20.1-0.30.10.10.10.1-0.50.20.2-0.5-0.50.2
Median of all reaction times0.10.21.4-0.2-0.4-0.20.70.20.1-0.4-0.2-0.5-0.5-0.5-0.5-0.4-0.4-0.40.0-0.31.2
Reaction time omissions1.82.94.81.91.41.8-1.9-1.82.2-1.71.9-1.7-1.7-1.7-1.71.4-1.6-1.61.41.32.0
Reaction time false alarm rate1.62.36.82.11.71.6-2.2-0.61.9-1.42.6-1.4-1.3-1.3-1.20.2-1.5-1.51.4-0.30.4
Reaction time premature initiation rate0.10.20.40.50.30.2-0.5-0.30.6-0.30.6-0.4-0.4-0.4-0.40.4-0.4-0.40.30.40.2
Reaction time premature initiations0.00.11.10.00.1-0.1-0.2-0.30.2-0.1-0.1-0.2-0.3-0.3-0.30.8-0.1-0.10.21.00.1
Std. dev. reaction times0.00.10.50.4-0.00.1-0.60.20.20.30.70.20.20.20.2-0.40.30.3-0.5-0.5-0.4
Reaction time trials completed0.10.21.2-0.6-0.2-0.20.5-0.2-0.40.1-1.00.20.00.1-0.10.90.30.3-0.11.10.1
Reaction time trials AUC0.10.31.3-0.7-0.4-0.40.7-0.1-0.60.2-1.10.30.10.20.00.70.40.4-0.20.90.0
Run reversals in cocaine runway, females0.10.10.2-0.3-0.2-0.5-0.20.2-0.2-0.1-0.10.30.30.30.20.30.20.2-0.10.5-0.3
Run reversals in cocaine runway, males0.30.30.8-0.1-0.30.00.1-0.0-0.30.6-0.20.80.90.80.9-0.30.80.8-0.7-0.3-0.9
Latency to leave start box in cocaine runway0.10.20.6-0.4-0.3-0.40.30.5-0.40.7-0.20.40.40.40.4-0.80.30.3-0.2-0.7-0.2
Latency to leave start box in cocaine runway, F0.10.10.40.40.30.4-0.3-0.10.3-0.30.6-0.2-0.3-0.3-0.4-0.5-0.2-0.20.4-0.60.4
Latency to leave start box in cocaine runway, M1.31.23.0-1.3-1.1-1.41.01.3-1.21.7-1.10.91.11.11.3-0.80.90.9-0.8-0.5-0.9
Std. dev. time between licks in bursts0.61.11.90.81.31.1-0.3-1.00.7-1.20.3-1.1-1.1-1.1-1.11.4-1.0-1.01.21.20.6
Total sessions with >9 infusions0.50.62.10.4-0.2-0.0-0.70.30.00.90.90.80.80.80.8-1.10.90.9-0.5-1.5-1.0
Short access day 1 total inactive lever presses0.40.81.8-0.1-0.6-0.3-0.20.0-0.41.10.01.31.41.31.4-0.61.21.2-0.9-0.5-1.3
Short access day 10 total inactive lever presses0.10.81.7-0.6-0.9-0.90.00.5-0.50.8-0.21.01.21.21.3-0.81.11.1-1.0-0.6-0.7
Short access day 1 total infusions0.30.62.4-0.1-0.5-0.3-0.50.2-0.21.60.31.01.11.11.1-0.70.80.8-0.7-0.8-0.7
Short access day 10 total infusions0.30.61.60.7-0.10.3-0.90.20.20.61.10.80.60.60.5-1.00.70.7-0.5-1.3-1.1
Short access total infusions0.40.61.70.1-0.3-0.3-0.40.5-0.31.10.41.00.90.90.9-1.00.90.9-0.7-1.1-1.3
Short access day 1 locomotion0.20.30.6-0.2-0.6-0.4-0.00.6-0.40.60.10.70.60.60.5-0.60.60.6-0.4-0.7-0.8
Short access day 10 total locomotion0.00.10.30.1-0.0-0.2-0.20.40.1-0.00.40.20.00.0-0.0-0.50.10.1-0.1-0.6-0.2
Short access total locomotion0.10.21.10.40.00.1-0.50.20.10.30.60.50.30.30.2-0.70.40.4-0.3-1.1-0.6
One hour access (0.3 mA shock)3.13.74.7-1.7-2.1-1.91.51.9-1.82.2-1.32.02.02.02.0-2.12.12.1-2.0-1.9-1.8
Compulsive drug intake0.91.34.9-1.1-1.4-1.61.02.2-1.00.6-0.40.70.70.70.6-1.70.80.8-0.8-1.7-0.8
One hour access (shock baseline)0.92.33.7-1.1-1.4-0.90.90.4-1.31.9-1.11.91.91.91.9-1.21.91.9-1.9-1.0-1.4
Social response proportion0.60.72.91.10.70.9-1.7-1.21.1-0.41.1-0.3-0.3-0.3-0.31.1-0.3-0.30.21.20.3
Social responses1.31.73.41.51.51.4-1.8-1.21.4-1.11.5-1.2-1.2-1.2-1.31.2-1.2-1.21.31.00.6
Social time0.60.93.20.90.81.0-1.1-1.61.0-0.60.7-0.6-0.6-0.6-0.61.6-0.5-0.50.71.80.7
Soleus weight0.82.33.3-1.6-1.5-1.71.21.3-1.71.6-1.81.71.61.61.6-0.11.71.7-1.70.2-1.8
Bone: stiffness1.52.87.5-2.5-1.9-2.42.72.7-2.10.7-2.10.70.70.70.8-1.90.70.7-0.8-1.8-0.2
Tibialis anterior weight5.418.726.1-4.2-4.4-4.43.45.0-4.64.4-3.34.34.34.34.3-5.14.14.1-4.1-5.0-3.9
Time to tail flick, vehicle, before self-admin0.20.30.7-0.1-0.4-0.3-0.20.3-0.30.60.10.50.60.60.7-0.40.70.7-0.8-0.4-0.8
Time to tail flick, vehicle, after self-admin0.10.20.6-0.7-0.7-0.50.80.2-0.5-0.1-0.8-0.0-0.0-0.0-0.00.1-0.1-0.1-0.10.20.4
Time to tail flick, test, before self-admin0.30.32.10.90.70.6-1.5-0.40.60.11.1-0.2-0.1-0.1-0.10.30.10.1-0.10.2-0.7
Time to tail flick, test, after self-admin0.91.02.0-1.2-1.0-1.40.91.2-1.11.2-1.10.81.01.01.1-0.30.90.9-0.70.1-0.9
Delta time to tail flick, vehicle, before/after SA0.50.62.3-0.4-0.30.00.9-0.2-0.0-1.0-0.7-0.8-0.9-0.9-1.00.4-0.9-0.90.70.41.5
Delta time to tail flick, test, before/after SA0.40.41.7-1.1-0.8-1.11.30.6-0.70.4-1.10.20.40.40.5-0.10.10.10.10.20.4
Tibia length0.20.51.9-1.1-1.1-0.91.40.5-0.70.3-1.10.40.50.40.5-0.50.40.4-0.7-0.30.7
Ambulatory time before self-admin0.10.41.5-0.3-0.4-0.6-0.00.6-0.50.6-0.10.70.70.80.7-0.30.90.9-1.0-0.2-1.2
Ambulatory time after self-admin0.30.51.2-0.6-1.0-0.80.00.1-0.40.8-0.50.80.80.80.80.21.11.1-1.00.5-0.4
Bone: tissue strength1.81.92.4-1.5-1.4-1.41.11.4-1.61.4-1.31.41.51.41.5-1.41.31.3-1.1-1.3-1.1
Total heroin consumption0.70.82.4-1.4-1.5-1.21.61.0-1.10.2-1.30.50.40.50.4-0.60.50.5-0.5-0.60.4
Bone: trabecular number0.20.30.8-0.6-0.2-0.70.90.7-0.3-0.5-0.6-0.6-0.5-0.5-0.40.3-0.7-0.70.50.40.5
Bone: trabecular spacing0.30.51.8-0.0-0.5-0.2-0.10.5-0.30.60.20.70.60.60.6-1.20.80.8-0.7-1.3-0.6
Bone: trabecular thickness0.10.10.40.20.40.2-0.3-0.00.3-0.40.5-0.5-0.4-0.4-0.40.1-0.5-0.50.60.00.3
Bone: trabecular tissue density0.30.52.70.80.40.5-1.00.30.5-0.31.5-0.3-0.3-0.3-0.2-1.3-0.3-0.30.4-1.60.0
Water consumed over 24 hours0.10.30.6-0.30.3-0.00.8-0.1-0.1-0.5-0.7-0.5-0.5-0.5-0.50.6-0.6-0.60.70.60.6
Number of responses in last shaping day1.41.83.91.61.51.7-1.8-2.01.5-0.81.2-0.9-0.9-0.9-0.82.0-1.0-1.01.01.80.4