Hub : Genes

Parvg

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Parvg 0.23 0.1 1.1e-13 0.28 0.3 0.3 0.31 1.3e-12 9.8e-14 1.1e-13 4.5e-14
2 PL gene expression Parvg 0.21 0.09 0.0e+00 0.26 0.28 0.26 0.28 2.6e-28 8.2e-31 4.7e-29 3.7e-31
3 Brain gene expression Parvg 0.21 0.06 0.0e+00 0.36 0.35 0.38 0.38 3.9e-35 7.2e-34 8.8e-37 1.4e-37
4 Brain alternative TSS XM_006241411.3 0.03 0.02 5.2e-04 0.03 0.01 0.02 0 1.8e-03 5.0e-02 1.1e-02 1.7e-01
5 Brain alternative TSS XM_006241411.3 0.03 0.02 4.4e-04 0.03 0.01 0.01 0 1.5e-03 4.8e-02 1.6e-02 1.6e-01
6 Brain isoform ratio NM_001130583.1 0.02 0.02 8.0e-03 0.01 0.01 0 0.01 2.6e-02 4.1e-02 2.0e-01 2.1e-02
7 OFC gene expression Parvg 0.37 0.15 1.3e-07 0.2 0.22 0.21 0.18 1.5e-05 7.0e-06 8.7e-06 3.6e-05
8 Adipose alternative polyA XM_039079916.1 0.06 0.04 5.3e-07 0.03 0.01 0.03 0 2.4e-04 2.0e-02 4.4e-04 3.2e-01
9 NAcc gene expression Parvg 0.3 0.11 0.0e+00 0.35 0.36 0.36 0.36 1.0e-41 1.8e-43 3.2e-43 1.2e-43
10 Brain alternative polyA XM_006241411.3 0.1 0.09 3.6e-05 0.06 0.03 0.04 0.05 6.6e-06 2.0e-03 2.2e-04 3.2e-05
11 Brain isoform ratio XM_006241411.3 0.06 0.04 3.3e-05 0.06 0.04 0.04 0.05 4.6e-06 3.0e-04 1.3e-04 3.2e-05
12 Brain alternative polyA XM_006241411.3 0.15 0.14 2.4e-06 0.07 0.04 0.06 0.06 3.3e-07 7.9e-05 6.0e-06 1.3e-06
13 Brain alternative polyA NM_001130583.1 0.09 0.08 3.9e-05 0.06 0.02 0.04 0.05 7.7e-06 2.6e-03 3.1e-04 3.9e-05
14 Brain alternative polyA NM_001130583.1 0.04 0.04 1.6e-03 0.03 0.01 0.01 0.03 6.8e-04 2.5e-02 1.3e-02 1.7e-03
15 BLA gene expression Parvg 0.15 0.09 8.3e-09 0.11 0.13 0.13 0.14 2.3e-06 1.2e-07 1.6e-07 6.9e-08
16 LHb gene expression Parvg 0.43 0.18 4.3e-06 0.15 0.19 0.2 0.2 2.0e-04 2.7e-05 1.6e-05 1.5e-05
17 Adipose gene expression Parvg 0.33 0.14 0.0e+00 0.23 0.13 0.24 0.09 1.5e-25 3.2e-14 5.5e-26 7.0e-10
18 Brain alternative polyA XM_039079916.1 0.06 0.03 8.5e-07 0.06 0.02 0.05 0.03 1.9e-06 5.2e-03 1.0e-05 5.4e-04
19 Liver gene expression Parvg 0.13 0.07 7.8e-12 0.08 0.03 0.09 0.1 4.9e-09 2.1e-04 2.2e-10 9.2e-11
20 IL gene expression Parvg 0.5 0.15 2.3e-07 0.24 0.22 0.22 0.21 1.6e-06 6.7e-06 4.8e-06 7.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.30.51.2-0.9-0.7-0.61.11.10.6-0.9-0.5-0.70.50.50.5-0.5-0.5-0.8-0.60.6-0.6-0.50.2
Area under the delay curve1.81.93.0-1.7-1.7-1.41.51.51.6-1.5-1.7-1.41.41.41.4-1.4-1.4-1.3-1.21.7-0.6-0.40.1
BMI with tail1.96.27.62.62.62.5-2.5-2.5-2.52.82.62.4-2.6-2.6-2.62.62.62.62.6-2.62.02.2-2.1
BMI without tail0.91.83.61.51.41.4-1.3-1.3-1.91.61.41.3-1.5-1.5-1.51.51.51.70.8-1.11.10.1-0.3
Body weight0.93.85.62.42.22.0-2.2-2.2-2.12.22.01.8-2.0-2.0-2.02.02.01.81.7-1.91.61.4-0.7
Weight adjusted by age0.60.71.60.70.70.8-0.6-0.6-1.30.80.70.6-1.2-1.2-1.21.21.11.10.4-0.50.70.20.2
Bone surface0.00.00.1-0.3-0.1-0.10.40.40.2-0.4-0.1-0.20.10.10.1-0.1-0.1-0.3-0.00.2-0.10.00.2
Bone volume0.00.10.3-0.3-0.1-0.10.50.50.1-0.4-0.0-0.20.00.00.0-0.0-0.1-0.2-0.10.2-0.2-0.10.3
Breakpoint value in progressive ratio session0.20.20.40.40.40.5-0.1-0.1-0.60.50.50.5-0.6-0.6-0.60.60.50.60.4-0.40.60.4-0.3
Number of licking bursts1.01.11.8-0.9-1.0-1.20.30.31.0-1.1-1.2-1.21.21.21.2-1.2-1.1-1.0-1.41.3-1.2-1.30.6
Context. condit. distance diff. score3.84.67.42.62.52.1-2.7-2.7-2.02.32.22.1-2.0-2.0-2.02.02.02.12.0-2.11.61.6-1.4
Locomotion velocity, session 12.62.85.01.51.62.0-1.2-1.2-1.71.61.81.9-1.8-1.8-1.81.81.81.51.7-1.52.21.8-0.9
Locomotion distance, session 10.00.00.1-0.1-0.10.0-0.0-0.00.1-0.1-0.00.0-0.0-0.0-0.00.00.0-0.20.10.00.30.3-0.0
Locomotion velocity, session 23.33.96.22.02.02.3-1.5-1.5-2.52.12.22.1-2.2-2.2-2.22.22.22.11.6-1.72.21.10.1
Locomotion distance, session 20.10.10.3-0.3-0.3-0.00.60.60.2-0.1-0.00.0-0.0-0.0-0.00.00.0-0.20.2-0.00.10.4-0.6
Locomotion velocity, session 31.92.23.51.51.61.6-1.5-1.5-1.91.51.61.5-1.6-1.6-1.61.61.61.71.1-1.21.30.60.3
Locomotion distance, session 30.40.53.7-0.4-0.4-0.50.40.40.1-0.5-0.3-0.60.40.40.4-0.4-0.4-0.3-0.80.6-0.8-1.21.9
Stereotopy head waving bouts, day 32.93.54.31.61.72.1-1.3-1.3-2.01.82.02.0-2.1-2.1-2.12.12.12.01.9-1.81.91.7-1.4
Stereotopy head waving duration, day 35.66.77.72.72.72.8-2.6-2.6-2.72.62.62.7-2.7-2.7-2.72.72.72.62.4-2.42.72.1-1.6
Locomotion velocity, session 70.20.20.60.60.40.4-0.4-0.4-0.60.60.40.4-0.5-0.5-0.50.50.50.80.1-0.40.3-0.10.3
Locomotion distance, session 70.20.20.6-0.5-0.6-0.40.80.80.4-0.3-0.4-0.40.40.40.4-0.4-0.4-0.2-0.40.3-0.6-0.40.2
Stereotopy head waving bouts, day 75.15.77.82.82.82.5-2.7-2.7-2.72.52.62.3-2.5-2.5-2.52.52.52.52.0-2.21.91.3-0.3
Stereotopy head waving duration, day 72.12.64.12.01.91.7-2.0-2.0-1.91.71.71.5-1.6-1.6-1.61.61.61.61.1-1.31.30.6-0.1
Locomotion velocity, session 810.012.014.33.73.73.8-3.2-3.2-3.53.63.83.6-3.5-3.5-3.53.53.53.53.5-3.53.43.0-2.3
Locomotion distance, session 81.92.83.71.91.91.8-1.6-1.6-1.81.81.91.8-1.7-1.7-1.71.71.71.81.6-1.71.31.1-0.9
Degree of sensitization distance1.31.35.70.90.91.0-0.6-0.6-0.61.10.91.1-1.0-1.0-1.01.01.00.91.4-1.21.21.7-2.4
Degree of sensitization stereotypy2.32.64.72.12.01.6-2.2-2.2-1.81.71.71.5-1.6-1.6-1.61.61.61.51.2-1.41.20.60.3
Conditioned locomotion0.70.81.3-0.6-0.8-1.10.30.30.9-0.8-1.2-1.10.90.90.9-0.9-0.9-1.0-1.10.9-1.0-1.10.8
Cocaine response after cond. corrected0.20.20.9-0.1-0.2-0.5-0.2-0.20.1-0.3-0.4-0.40.30.30.3-0.3-0.3-0.3-0.70.4-0.8-1.00.9
Cocaine response after cond. not corrected0.40.42.4-0.1-0.2-0.6-0.2-0.20.1-0.4-0.4-0.60.40.40.4-0.4-0.4-0.4-0.90.5-0.9-1.31.6
Cocaine response before conditioning0.20.20.7-0.5-0.4-0.50.20.20.5-0.5-0.4-0.50.50.50.5-0.5-0.5-0.4-0.50.5-0.5-0.50.8
Saline control response0.10.11.1-0.00.1-0.1-0.2-0.2-0.1-0.3-0.0-0.10.10.10.1-0.1-0.1-0.2-0.40.4-0.0-0.51.0
Bone: connectivity density0.10.20.5-0.6-0.5-0.40.70.70.4-0.7-0.5-0.50.40.40.4-0.4-0.4-0.5-0.50.5-0.3-0.3-0.0
Bone: cortical apparent density0.81.02.3-1.4-1.2-0.81.51.51.2-1.0-1.0-0.71.01.01.0-1.0-1.0-0.9-0.50.8-0.30.1-1.0
Bone: cortical area0.40.51.41.10.90.6-1.2-1.2-0.70.80.60.5-0.7-0.7-0.70.70.70.60.5-0.70.40.30.1
Bone: cortical porosity0.10.10.20.50.30.1-0.4-0.4-0.30.30.20.1-0.2-0.2-0.20.20.20.20.0-0.10.0-0.0-0.1
Bone: cortical porosity0.30.30.70.80.70.4-0.8-0.8-0.60.60.50.4-0.6-0.6-0.60.60.50.50.3-0.40.30.10.1
Bone: cortical thickness0.20.20.6-0.5-0.5-0.60.50.50.7-0.4-0.6-0.50.40.40.4-0.4-0.4-0.6-0.10.2-0.60.2-0.8
Bone: cortical thickness0.10.10.50.20.1-0.1-0.3-0.30.10.2-0.1-0.1-0.2-0.2-0.20.20.10.10.4-0.3-0.10.5-0.7
Bone: cortical tissue density0.60.82.1-1.2-1.1-0.71.41.41.1-0.9-0.8-0.60.80.80.8-0.8-0.8-0.7-0.30.6-0.20.2-1.1
Condit. Reinf. active minus inactive responses1.92.13.2-1.5-1.7-1.71.21.21.7-1.4-1.8-1.61.61.61.6-1.6-1.6-1.5-1.41.4-1.2-0.90.4
Condit. Reinf. active-inactive response ratio1.01.12.1-0.8-1.0-1.30.10.11.3-1.0-1.4-1.31.21.21.2-1.2-1.2-1.1-1.01.0-0.9-0.60.3
Condit. Reinf. active responses2.73.34.6-2.0-2.1-2.01.91.91.9-1.8-2.1-1.91.81.81.8-1.8-1.8-1.7-1.91.8-1.5-1.40.9
Condit. Reinf. inactive responses0.91.13.2-1.4-1.3-0.91.81.80.8-1.0-0.9-0.90.90.90.9-0.9-0.9-0.8-1.01.0-0.7-0.90.5
Incentive salience index mean2.22.73.8-1.8-2.0-1.81.61.61.8-1.6-1.9-1.71.71.71.7-1.7-1.7-1.6-1.61.6-1.4-1.10.6
Condit. Reinf. lever presses1.11.42.7-1.5-1.5-1.21.71.71.1-1.1-1.2-1.21.11.11.1-1.1-1.1-0.9-1.11.1-1.2-1.00.6
Condit. Reinf. active minus inactive responses0.20.21.20.10.20.5-0.2-0.20.20.20.30.5-0.1-0.1-0.10.10.00.00.6-0.31.01.1-1.1
Condit. Reinf. active-inactive response ratio0.10.11.10.20.20.4-0.2-0.20.10.10.30.4-0.1-0.1-0.10.10.00.00.4-0.20.60.7-1.1
Condit. Reinf. active responses1.11.54.31.01.11.5-1.0-1.0-0.71.11.11.5-1.0-1.0-1.01.00.90.91.4-1.12.11.9-1.2
Condit. Reinf. inactive responses1.41.84.01.21.21.5-1.0-1.0-1.11.41.21.5-1.3-1.3-1.31.31.21.21.5-1.22.01.9-0.8
Condit. Reinf. lever presses0.30.41.70.30.30.80.00.0-0.50.60.60.9-0.6-0.6-0.60.60.60.70.7-0.51.30.9-0.5
Condit. Reinf. lever reinforcers received0.60.83.10.50.61.1-0.4-0.4-0.30.70.81.2-0.6-0.6-0.60.60.50.61.1-0.81.81.7-1.1
Conditioned reinforcement - actives0.50.51.0-0.7-0.6-0.60.60.61.0-0.8-0.6-0.50.80.80.8-0.8-0.9-0.9-0.30.4-0.7-0.10.2
Conditioned reinforcement - inactives0.10.10.30.00.10.20.10.1-0.20.10.10.2-0.3-0.3-0.30.30.30.30.3-0.20.40.5-0.5
Conditioned locomotion1.31.52.61.31.21.5-0.9-0.9-1.61.11.31.3-1.4-1.4-1.41.41.41.31.1-1.01.20.8-0.3
Patch foraging indifference point 0 sec0.10.10.2-0.4-0.3-0.30.40.40.3-0.4-0.2-0.20.40.40.4-0.4-0.3-0.4-0.10.3-0.4-0.2-0.2
Patch foraging indifference point AUC0.10.10.4-0.4-0.3-0.20.60.60.5-0.2-0.2-0.10.30.30.3-0.3-0.3-0.20.1-0.1-0.40.2-0.7
Delay disc. indifference point, 0s delay0.10.10.30.30.30.2-0.5-0.5-0.40.40.10.2-0.3-0.3-0.30.30.30.30.0-0.10.50.1-0.1
Delay disc. indifference point, 16s delay2.42.44.1-1.9-1.9-1.52.02.01.6-1.7-1.6-1.51.51.51.5-1.5-1.5-1.5-1.41.7-1.2-0.90.8
Delay disc. indifference point, 2s delay0.50.51.0-0.8-0.9-0.80.50.50.9-0.8-1.0-0.80.80.80.8-0.8-0.8-0.7-0.60.9-0.1-0.0-0.5
Delay disc. indifference point, 24s delay0.50.50.9-0.8-0.9-0.70.90.90.8-0.6-0.8-0.60.70.70.7-0.7-0.7-0.6-0.50.7-0.3-0.0-0.2
Delay disc. indifference point, 4s delay0.20.21.7-0.4-0.3-0.00.20.20.5-0.3-0.40.00.20.20.2-0.2-0.2-0.20.20.50.91.0-1.3
Delay disc. indifference point, 8s delay2.82.94.1-1.9-2.0-1.81.81.81.8-1.8-1.9-1.81.71.71.7-1.7-1.7-1.7-1.61.9-1.4-1.20.7
Indifference point function ln k0.81.12.01.21.31.2-1.0-1.0-1.41.11.21.0-1.1-1.1-1.11.11.11.00.7-0.80.90.30.4
Indifference point function log k0.81.12.01.21.31.2-1.0-1.0-1.41.11.21.0-1.1-1.1-1.11.11.11.00.7-0.80.90.30.4
Patch foraging total patch changes 0 sec0.20.20.4-0.5-0.5-0.50.50.50.5-0.6-0.5-0.40.60.60.6-0.6-0.5-0.5-0.40.6-0.5-0.40.0
Patch foraging total patch changes 12 sec0.10.10.70.20.20.0-0.1-0.10.20.30.10.2-0.1-0.1-0.10.10.10.10.6-0.4-0.10.6-0.8
Patch foraging total patch changes 18 sec0.30.40.8-0.8-0.6-0.60.70.70.8-0.9-0.6-0.50.60.60.6-0.6-0.6-0.6-0.30.5-0.6-0.1-0.6
Patch foraging total patch changes 24 sec0.00.00.1-0.20.00.10.30.3-0.3-0.00.20.1-0.2-0.2-0.20.20.20.2-0.00.0-0.1-0.30.1
Patch foraging total patch changes 6 sec0.20.30.7-0.4-0.4-0.60.30.30.8-0.5-0.5-0.40.60.60.6-0.6-0.5-0.60.10.2-0.60.2-0.9
Patch foraging time to switch 0 sec0.10.10.5-0.2-0.10.20.70.7-0.3-0.00.20.2-0.1-0.1-0.10.10.20.2-0.10.10.1-0.20.6
Patch foraging water rate 0 sec0.30.51.70.90.80.4-1.3-1.3-0.50.70.60.5-0.5-0.5-0.50.50.50.40.5-0.70.10.3-0.7
Patch foraging water rate 12 sec0.40.71.50.90.90.6-1.2-1.2-1.20.60.70.5-0.9-0.9-0.90.90.80.70.0-0.30.4-0.40.9
Patch foraging water rate 18 sec0.00.00.2-0.0-0.0-0.2-0.4-0.4-0.1-0.1-0.2-0.2-0.2-0.2-0.20.20.2-0.2-0.10.1-0.1-0.10.4
Patch foraging water rate 24 sec1.31.92.81.51.51.3-1.5-1.5-1.71.41.51.2-1.5-1.5-1.51.51.51.31.2-1.30.90.7-0.5
Patch foraging water rate 6 sec0.20.21.2-0.5-0.5-0.50.20.20.2-0.5-0.5-0.60.20.20.2-0.2-0.3-0.4-0.70.6-0.3-0.61.1
Seeking ratio, delayed vs. immediate footshock2.22.53.0-1.7-1.5-1.61.41.41.5-1.7-1.4-1.61.71.71.7-1.7-1.6-1.5-1.71.5-1.7-1.71.5
Distance traveled before self-admin0.10.10.6-0.1-0.1-0.00.20.20.4-0.00.0-0.10.20.20.2-0.2-0.2-0.30.2-0.3-0.20.2-0.8
Distance traveled after self-admin0.80.91.30.80.91.1-0.5-0.5-1.00.81.01.1-1.0-1.0-1.01.01.01.01.0-0.91.11.1-0.8
Extensor digitorum longus weight0.10.41.10.70.60.7-0.4-0.4-1.10.80.70.6-0.8-0.8-0.80.80.80.80.3-0.50.5-0.10.1
Bone: elastic displacement1.41.52.31.41.41.4-1.5-1.5-1.41.21.31.2-1.2-1.2-1.21.21.21.30.9-1.01.50.8-0.2
Bone: elastic work5.16.68.52.92.82.7-2.8-2.8-2.92.72.72.6-2.7-2.7-2.72.72.72.62.3-2.42.41.7-1.0
Bone: endosteal estimation2.96.39.03.02.92.7-2.7-2.7-3.02.72.82.5-2.6-2.6-2.62.62.62.61.9-2.22.21.20.1
Bone: endosteal perimeter1.63.45.62.42.32.0-2.3-2.3-2.41.92.11.7-1.8-1.8-1.81.81.81.80.9-1.31.50.01.3
Epididymis fat weight0.40.81.81.41.11.0-1.2-1.2-0.81.00.91.0-0.7-0.7-0.70.70.70.80.9-1.00.80.8-0.3
Delta time in closed arm before/after self-admin0.20.21.50.00.10.40.10.10.10.10.20.4-0.2-0.2-0.20.20.20.30.7-0.20.91.2-1.2
Delta time in open arm before/after self-admin0.60.61.80.90.80.7-0.8-0.8-1.30.70.70.6-0.8-0.8-0.80.80.91.0-0.0-0.40.5-0.50.7
Diff in mean of infusions in LGA sessions0.60.62.0-1.0-0.9-0.70.90.91.4-0.9-0.8-0.60.80.80.8-0.8-0.8-0.80.10.3-0.30.7-0.6
Delay discount exponential model param1.71.82.91.61.71.4-1.5-1.5-1.51.41.71.3-1.3-1.3-1.31.31.31.31.1-1.70.50.30.0
Extinction: sum of active levers before priming0.10.10.6-0.1-0.2-0.10.40.40.10.2-0.2-0.1-0.1-0.1-0.10.10.00.1-0.0-0.10.20.3-0.8
Active lever presses in extinction session 60.50.50.90.80.50.5-0.9-0.9-0.40.80.30.6-0.6-0.6-0.60.60.60.60.6-0.61.00.9-0.8
Bone: final force0.81.42.51.31.21.1-1.1-1.1-0.81.21.11.1-1.1-1.1-1.11.11.11.01.4-1.31.11.6-1.5
Bone: final moment1.42.23.51.61.51.4-1.5-1.5-1.11.51.41.4-1.4-1.4-1.41.41.41.21.8-1.61.31.9-1.9
Food consumed during 24 hour testing period2.73.24.71.91.81.7-2.0-2.0-1.41.81.61.7-1.7-1.7-1.71.71.61.52.0-1.81.72.2-2.1
Glucose1.52.33.3-1.6-1.6-1.71.41.41.8-1.7-1.7-1.61.61.61.6-1.6-1.7-1.7-1.31.4-1.4-0.9-0.1
Heart weight0.30.41.81.00.80.5-1.4-1.4-0.20.50.40.5-0.3-0.3-0.30.30.40.30.5-0.50.60.6-0.7
Delay discount hyperbolic model param1.21.32.21.41.41.1-1.2-1.2-1.31.21.41.1-1.1-1.1-1.11.11.11.10.9-1.50.30.10.1
Intermittent access intake day 1-15 change0.60.61.7-0.9-0.8-0.80.80.80.6-0.8-0.7-0.70.60.60.6-0.6-0.6-0.8-0.70.7-0.8-0.81.3
Intermittent access intake escalation0.60.62.3-0.8-0.8-0.70.70.70.5-0.7-0.7-0.70.60.60.6-0.6-0.6-0.8-0.80.8-0.7-0.91.5
Intermittent access intake escalation 20.30.30.7-0.5-0.4-0.50.30.30.7-0.7-0.4-0.50.70.70.7-0.7-0.7-0.8-0.40.5-0.6-0.40.9
Intermitt. access day 1 inactive lever presses2.32.43.41.31.31.5-1.1-1.1-1.61.51.31.6-1.7-1.7-1.71.71.71.71.7-1.41.81.8-1.7
Intermitt. access day 15 inactive lever presses1.92.15.91.21.21.3-1.0-1.0-0.91.51.21.4-1.3-1.3-1.31.31.31.21.9-1.71.52.2-2.4
Intermitt. access escalation Index0.00.00.20.20.10.2-0.2-0.20.00.00.20.10.10.10.1-0.1-0.1-0.00.1-0.00.20.0-0.4
Intermittent access day 1 total infusions0.40.50.90.90.80.8-0.7-0.7-0.50.70.70.8-0.5-0.5-0.50.50.50.61.0-0.80.60.9-0.9
Intermittent access day 15 total infusions0.10.10.20.30.40.4-0.4-0.4-0.20.20.40.4-0.1-0.1-0.10.10.10.10.4-0.30.10.20.4
Intermittent access terminal intake (last 3 days)0.20.20.30.40.40.5-0.5-0.5-0.40.40.50.5-0.5-0.5-0.50.50.30.30.5-0.50.20.40.0
Intermittent access total infusions0.20.20.50.70.70.6-0.7-0.7-0.40.50.60.6-0.3-0.3-0.30.30.30.20.6-0.50.30.4-0.1
Intermittent access day 1 locomotion0.00.00.10.20.20.1-0.2-0.2-0.20.00.10.1-0.0-0.0-0.00.00.00.10.0-0.0-0.2-0.3-0.1
Intermittent access day 15 total locomotion0.40.41.10.60.60.5-0.7-0.7-1.00.60.60.6-0.7-0.7-0.70.70.70.80.3-0.40.2-0.20.4
Intermittent access total locomotion0.70.81.50.80.90.9-0.8-0.8-1.20.90.90.9-1.0-1.0-1.01.01.01.10.6-0.80.60.2-0.3
Intermittent access standard deviation0.80.81.01.01.01.0-0.8-0.8-0.90.91.01.0-1.0-1.0-1.01.01.00.81.0-0.90.80.9-0.5
Left kidney weight14.741.551.17.16.96.8-6.3-6.3-6.77.06.76.6-6.7-6.7-6.76.76.76.66.3-6.45.85.2-3.9
Right kidney weight16.245.456.27.57.37.1-6.8-6.8-6.87.27.07.0-6.9-6.9-6.96.96.96.76.8-6.86.15.8-4.2
Cocaine induced anxiety3.64.25.42.12.22.1-1.9-1.9-2.12.32.12.1-2.1-2.1-2.12.12.12.02.0-2.32.01.8-1.6
Post-drug Anxiety2.12.32.91.61.41.5-1.3-1.3-1.61.71.31.5-1.7-1.7-1.71.71.71.51.4-1.51.71.5-1.3
Baseline Anxiety3.23.44.3-1.9-2.1-1.92.02.01.9-2.0-2.1-1.81.81.81.8-1.8-1.8-1.8-1.72.0-1.7-1.51.4
Tail length0.10.30.7-0.4-0.5-0.30.40.40.3-0.4-0.5-0.40.50.50.5-0.5-0.5-0.5-0.80.6-0.2-0.80.8
Length with tail0.00.10.20.40.20.3-0.2-0.2-0.30.20.10.2-0.2-0.2-0.20.20.2-0.0-0.0-0.10.40.00.3
Length without tail0.40.92.80.90.81.0-0.4-0.4-0.60.80.91.0-1.0-1.0-1.01.00.90.61.4-1.11.01.7-1.0
Times rat made contact with spout1.31.52.71.21.31.2-1.5-1.5-0.91.11.11.3-1.1-1.1-1.11.11.01.01.4-1.11.41.6-1.2
Lifetime Intake0.40.51.00.90.90.8-1.0-1.0-0.60.70.80.8-0.5-0.5-0.50.50.50.50.8-0.70.50.6-0.1
Liver weight, left0.40.72.60.50.50.9-0.4-0.4-0.60.60.60.9-0.8-0.8-0.80.80.80.60.8-0.51.51.2-1.6
Liver weight, right0.00.00.10.30.20.3-0.3-0.3-0.20.20.10.2-0.2-0.2-0.20.20.10.1-0.10.10.3-0.00.3
Locomotor activity1.52.34.01.81.71.2-2.0-2.0-1.81.51.41.1-1.8-1.8-1.81.81.81.51.2-1.40.60.7-0.2
Locomotor testing distance0.00.10.20.00.0-0.2-0.4-0.4-0.1-0.1-0.2-0.2-0.1-0.1-0.10.10.20.0-0.20.1-0.5-0.40.3
Locomotor testing rearing0.20.41.20.60.60.3-1.1-1.1-0.70.40.40.4-0.6-0.6-0.60.60.70.70.2-0.30.2-0.0-0.0
Locomotion in novel chamber0.60.83.7-0.5-0.4-0.40.40.40.1-0.9-0.3-0.50.70.70.7-0.7-0.6-0.7-1.31.1-0.8-1.81.9
Locomotion in novel chamber post-restriction0.80.92.0-1.1-1.0-0.91.21.20.7-0.9-0.8-1.00.80.80.8-0.8-1.0-0.9-1.11.1-0.6-1.01.4
Fecal boli incidents, locomotor time 10.10.10.4-0.3-0.00.30.30.3-0.40.30.20.3-0.4-0.4-0.40.40.50.60.3-0.00.50.4-0.7
Change in fecal boli incidents, locomotor task0.10.10.80.20.1-0.2-0.4-0.4-0.1-0.1-0.2-0.20.10.10.1-0.1-0.2-0.2-0.50.1-0.2-0.70.9
Time >=10cm from walls, locomotor time 10.30.30.40.40.50.7-0.2-0.2-0.50.50.60.6-0.5-0.5-0.50.50.50.50.5-0.50.60.4-0.5
Bouts of movement, locomotor time 10.00.00.2-0.1-0.2-0.10.30.30.2-0.1-0.1-0.10.10.10.1-0.1-0.0-0.10.00.1-0.10.1-0.4
Total resting periods, locomotor time 10.10.10.3-0.3-0.4-0.20.40.40.5-0.3-0.3-0.20.30.30.3-0.3-0.2-0.3-0.10.3-0.20.1-0.5
Rest time, locomotor task time 10.20.20.50.50.30.5-0.3-0.3-0.50.60.50.5-0.4-0.4-0.40.40.50.70.4-0.40.40.3-0.3
Distance moved, locomotor task time 10.00.00.10.10.30.3-0.1-0.1-0.10.00.30.2-0.2-0.2-0.20.20.1-0.10.2-0.10.40.3-0.2
Vertical activity count, locomotor time 10.00.00.1-0.2-0.00.00.10.10.2-0.3-0.1-0.00.10.10.1-0.1-0.1-0.40.10.20.30.30.1
Time >=10cm from walls, locomotor time 20.20.20.5-0.6-0.4-0.30.70.70.2-0.4-0.3-0.30.30.30.3-0.3-0.4-0.3-0.50.6-0.1-0.60.5
Bouts of movement, locomotor time 20.70.81.5-0.8-1.1-1.20.90.91.0-0.6-1.2-1.20.80.80.8-0.8-0.8-0.7-0.70.7-1.0-0.4-0.3
Total resting periods, locomotor time 20.80.81.6-0.9-1.1-1.30.80.81.1-0.6-1.3-1.20.90.90.9-0.9-0.9-0.7-0.70.6-1.1-0.4-0.4
Rest time, locomotor task time 20.20.20.5-0.6-0.5-0.50.30.30.5-0.5-0.5-0.50.50.50.5-0.5-0.5-0.3-0.40.4-0.5-0.30.7
Distance moved, locomotor task time 20.80.91.61.21.11.1-0.7-0.7-1.11.01.01.0-1.0-1.0-1.01.01.00.90.7-0.81.10.5-0.4
Vertical activity count, locomotor time 21.01.11.81.01.11.2-0.6-0.6-1.31.21.11.1-1.2-1.2-1.21.21.21.10.8-1.11.10.6-0.3
Light reinforcement 10.91.63.41.11.21.5-0.6-0.6-1.91.11.31.5-1.5-1.5-1.51.51.51.60.9-0.91.40.50.0
Light reinforcement 20.91.22.81.11.11.3-0.6-0.6-1.71.21.21.3-1.3-1.3-1.31.31.21.40.7-0.91.00.10.4
Bone: marrow area3.16.69.53.13.02.8-2.8-2.8-3.02.72.92.6-2.7-2.7-2.72.72.72.62.0-2.32.31.30.0
Bone: maximum diameter3.87.010.83.33.12.7-3.1-3.1-2.92.92.82.6-2.7-2.7-2.72.72.72.62.1-2.42.31.5-0.4
Bone: maximum force1.83.14.62.12.01.7-2.0-2.0-1.51.91.71.6-1.7-1.7-1.71.71.71.61.9-1.81.41.8-1.5
Bone: maximum moment2.54.26.22.52.31.9-2.4-2.4-1.72.22.01.9-2.0-2.0-2.02.02.01.82.2-2.21.72.1-1.9
Mean time between licks in bursts2.53.64.4-1.6-1.8-2.11.21.21.9-2.0-2.1-2.12.02.02.0-2.0-2.0-2.1-2.11.9-1.9-1.91.6
Mean num. licks in bursts3.64.37.31.92.02.3-1.6-1.6-1.72.02.12.3-2.1-2.1-2.12.11.91.92.5-2.12.52.7-1.5
Cd content in liver0.30.31.90.50.2-0.4-1.4-1.40.6-0.2-0.4-0.40.50.50.5-0.5-0.4-0.5-0.30.4-0.00.1-0.1
Co content in liver1.01.21.81.11.21.1-1.2-1.2-1.41.01.21.1-1.2-1.2-1.21.21.31.11.1-1.30.60.60.0
Cu content in liver6.37.610.2-3.0-2.8-2.63.23.22.4-2.8-2.5-2.62.72.72.7-2.7-2.6-2.6-2.82.9-2.4-2.72.8
Fe content in liver0.20.30.90.50.60.6-0.6-0.6-0.60.20.60.6-0.5-0.5-0.50.50.60.60.4-0.30.60.4-0.9
K content in liver0.50.51.30.10.30.80.40.4-0.50.50.70.9-0.7-0.7-0.70.70.70.81.0-0.51.01.1-1.1
Mg content in liver0.20.20.6-0.4-0.20.30.80.8-0.00.00.30.4-0.2-0.2-0.20.20.20.20.5-0.00.50.7-0.8
Mn content in liver0.60.71.40.60.81.0-0.5-0.5-1.10.91.01.0-1.0-1.0-1.01.01.01.20.9-0.70.80.6-0.0
Na content in liver3.53.75.4-1.8-1.9-2.21.41.42.3-2.0-2.1-2.02.22.22.2-2.2-2.2-2.1-1.71.8-2.0-1.40.2
Rb content in liver0.20.20.4-0.4-0.4-0.5-0.1-0.10.7-0.5-0.6-0.50.50.50.5-0.5-0.6-0.6-0.40.6-0.2-0.10.1
Se content in liver0.20.31.8-0.8-0.5-0.11.31.30.1-0.40.0-0.10.10.10.1-0.1-0.2-0.3-0.10.3-0.1-0.20.7
Sr content in liver0.70.60.9-0.7-0.8-0.90.70.70.7-0.8-0.8-0.90.80.80.8-0.8-0.8-0.8-0.80.7-0.9-0.80.7
Zn content in liver1.01.11.6-1.1-1.0-1.01.01.00.8-1.1-1.0-1.01.01.01.0-1.0-0.9-1.1-1.11.1-1.0-1.11.3
Bone: minimum diameter0.50.92.21.21.10.9-0.8-0.8-1.40.91.10.8-1.0-1.0-1.01.01.00.80.3-0.60.3-0.51.5
Time in familiar zone, hab. session 11.00.91.51.00.91.1-0.8-0.8-1.00.91.01.1-1.0-1.0-1.01.01.01.10.9-0.91.20.8-0.2
Time in novel zone, hab. session 10.40.41.5-0.1-0.1-0.8-0.6-0.60.5-0.4-0.6-0.80.50.50.5-0.5-0.5-0.6-0.60.4-1.2-0.90.2
Total zone transitions, hab. session 11.52.02.9-1.7-1.6-1.51.61.61.5-1.6-1.4-1.51.41.41.4-1.4-1.4-1.5-1.21.3-1.5-1.00.9
Total locomotion distance, hab. session 10.10.10.8-0.3-0.00.20.70.7-0.50.00.30.1-0.3-0.3-0.30.30.30.3-0.0-0.0-0.1-0.40.9
Locomotion velocity, hab. session 10.10.20.6-0.3-0.00.40.80.8-0.60.20.40.3-0.4-0.4-0.40.40.40.40.1-0.10.1-0.20.8
Time in familiar zone, hab. session 20.10.10.3-0.2-0.20.00.50.5-0.2-0.1-0.0-0.1-0.0-0.0-0.00.00.00.1-0.30.30.3-0.30.3
Time in novel zone, hab. session 20.10.10.90.30.3-0.1-0.9-0.90.20.00.0-0.00.00.00.0-0.0-0.0-0.20.3-0.3-0.50.1-0.4
Total zone transitions, hab. session 20.70.91.80.50.61.0-0.1-0.1-0.80.80.91.0-1.0-1.0-1.01.01.00.91.2-0.91.21.3-1.2
Total locomotion distance, hab. session 20.30.40.60.30.40.70.30.3-0.80.60.70.7-0.7-0.7-0.70.70.70.80.6-0.60.50.4-0.5
Locomotion velocity, hab. session 20.20.30.40.00.20.60.50.5-0.60.40.60.6-0.6-0.6-0.60.60.60.60.6-0.50.50.4-0.4
Novel to familiar place preference ratio0.50.52.11.11.00.6-1.4-1.4-0.60.70.60.5-0.6-0.6-0.60.60.60.40.5-0.60.30.2-0.1
Novelty place preference0.90.93.01.31.20.8-1.7-1.7-0.90.90.80.8-0.8-0.8-0.80.80.80.60.6-0.80.60.40.0
Time in novel zone, NPP test1.21.24.41.51.40.9-2.1-2.1-1.01.00.90.8-0.9-0.9-0.90.90.90.60.7-0.90.60.4-0.1
Total zone transitions, NPP test0.00.00.1-0.3-0.2-0.10.40.40.2-0.2-0.0-0.10.10.10.1-0.1-0.1-0.10.1-0.0-0.10.3-0.1
Total locomotion distance, NPP test0.20.30.80.30.50.70.10.1-0.90.50.80.6-0.7-0.7-0.70.70.70.80.5-0.50.40.10.2
Locomotion velocity, NPP test0.10.10.6-0.3-0.10.20.80.8-0.40.10.30.2-0.3-0.3-0.30.30.30.3-0.0-0.00.1-0.30.7
Intraocular pressure0.00.10.40.50.30.1-0.6-0.6-0.00.10.0-0.10.10.10.1-0.1-0.1-0.1-0.20.0-0.0-0.3-0.1
Delta distance traveled before/after self-admin2.32.54.01.51.61.8-1.5-1.5-1.91.41.51.7-1.7-1.7-1.71.71.81.91.3-1.12.01.30.1
Delta ambulatory time before/after self-admin1.82.03.31.51.51.6-1.5-1.5-1.61.21.41.5-1.4-1.4-1.41.41.51.61.2-0.91.81.3-0.1
Parametrial fat weight0.00.10.2-0.3-0.10.20.40.4-0.1-0.10.10.3-0.1-0.1-0.10.10.10.10.4-0.10.20.3-0.2
Pavlov. Cond. lever latency1.62.03.91.81.61.2-2.0-2.0-1.31.61.31.2-1.3-1.3-1.31.31.31.41.3-1.40.80.9-1.0
Pavlov. Cond. magazine entry latency3.14.05.5-2.2-2.2-2.22.02.02.3-2.2-2.2-2.12.12.12.1-2.1-2.1-2.2-1.61.8-1.9-1.10.7
Pavlov. Cond. change in total contacts3.23.44.7-2.2-2.1-1.92.12.12.1-2.0-2.0-1.81.91.91.9-1.9-1.9-2.0-1.61.8-1.4-0.90.8
Pavlov. Cond. index score2.22.83.7-1.9-1.8-1.71.81.81.9-1.8-1.7-1.61.71.71.7-1.7-1.7-1.8-1.31.5-1.4-0.90.6
Pavlov. Cond. latency score1.51.92.6-1.6-1.5-1.41.61.61.5-1.5-1.4-1.31.41.41.4-1.4-1.4-1.5-1.21.3-1.1-0.70.7
Pavlov. Cond. lever contacts2.22.64.6-2.0-1.8-1.52.12.11.5-1.8-1.5-1.51.51.51.5-1.5-1.5-1.6-1.51.6-1.3-1.21.2
Pavlov. Cond. magazine entry number3.54.46.02.22.32.3-2.1-2.1-2.52.22.32.1-2.2-2.2-2.22.22.22.31.8-1.91.91.2-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.5-0.4-0.30.40.40.2-0.4-0.3-0.30.20.20.2-0.2-0.2-0.2-0.30.3-0.1-0.10.2
Pavlov. Cond. lever-magazine prob. diff.2.93.74.7-2.1-2.1-2.02.12.12.2-2.1-2.0-1.92.02.02.0-2.0-2.0-2.1-1.61.8-1.7-1.20.9
Pavlov. Cond. response bias4.35.36.5-2.5-2.5-2.42.52.52.5-2.4-2.4-2.32.42.42.4-2.4-2.4-2.4-2.02.2-2.1-1.51.1
Pavlov. Cond. lever latency0.30.41.60.0-0.2-0.8-0.3-0.30.5-0.4-0.7-0.80.60.60.6-0.6-0.5-0.7-0.70.5-1.3-0.90.5
Pavlov. Cond. magazine entry latency0.60.73.0-1.3-1.1-0.41.71.70.8-0.8-0.6-0.30.70.70.7-0.7-0.6-0.5-0.30.60.20.2-0.6
Pavlov. Cond. change in total contacts0.60.82.70.20.51.10.10.1-0.50.61.01.1-0.8-0.8-0.80.80.70.81.3-0.91.51.7-1.2
Pavlov. Cond. index score0.20.21.3-0.7-0.50.21.11.10.2-0.20.00.30.10.10.1-0.1-0.10.00.30.10.80.7-0.3
Pavlov. Cond. latency score0.20.31.6-0.8-0.50.21.31.30.2-0.20.00.30.00.00.0-0.0-0.00.00.20.10.80.6-0.3
Pavlov. Cond. lever contacts0.40.51.60.10.30.90.30.3-0.50.50.70.9-0.7-0.7-0.70.70.60.80.9-0.61.31.1-0.8
Pavlov. Cond. magazine entry number0.30.32.00.80.5-0.3-1.4-1.4-0.20.2-0.0-0.3-0.0-0.0-0.00.0-0.0-0.1-0.3-0.1-0.8-0.70.6
Pavlov. Cond. intertrial magazine entries0.70.92.21.41.20.7-1.5-1.5-0.51.00.80.7-0.7-0.7-0.70.70.60.71.0-0.90.50.9-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.31.4-0.8-0.50.31.21.20.1-0.20.10.30.00.00.0-0.0-0.00.10.20.10.80.6-0.2
Pavlov. Cond. response bias0.20.31.1-0.3-0.10.50.70.7-0.10.10.40.6-0.3-0.3-0.30.30.30.40.6-0.31.01.0-1.0
Time in closed arm before self-admin1.92.22.7-1.6-1.6-1.61.11.11.3-1.6-1.5-1.61.51.51.5-1.5-1.4-1.6-1.61.4-1.6-1.50.9
Time in closed arm after self-admin0.20.20.5-0.5-0.4-0.30.20.20.4-0.7-0.4-0.40.50.50.5-0.5-0.4-0.5-0.40.5-0.2-0.30.6
Time in open arm before self-admin0.10.10.3-0.3-0.4-0.30.60.60.4-0.3-0.4-0.30.30.30.3-0.3-0.4-0.3-0.40.4-0.1-0.30.1
Time in open arm after self-admin0.50.61.40.80.70.7-0.4-0.4-1.21.00.80.7-0.9-0.9-0.90.90.91.10.1-0.50.6-0.3-0.1
Bone: periosteal estimation2.14.36.82.62.52.1-2.5-2.5-2.42.22.22.0-2.2-2.2-2.22.22.22.01.6-1.91.70.90.0
Bone: periosteal perimeter1.32.24.92.11.91.4-2.2-2.2-1.81.51.61.3-1.4-1.4-1.41.41.41.40.7-1.10.8-0.10.9
Bone: post-yield work0.20.21.30.60.4-0.0-0.8-0.80.40.30.00.0-0.0-0.0-0.00.00.10.10.7-0.6-0.01.0-1.1
Progressive ratio test 1 active lever presses0.10.10.4-0.3-0.2-0.30.20.20.4-0.4-0.2-0.30.40.40.4-0.4-0.4-0.3-0.20.4-0.6-0.2-0.2
Progressive ratio test 1 breakpoint0.30.30.6-0.6-0.5-0.50.40.40.6-0.6-0.5-0.50.50.50.5-0.5-0.6-0.6-0.40.6-0.8-0.4-0.1
Progressive ratio test 1 inactive lever presses0.10.11.00.30.20.3-0.1-0.1-0.30.30.10.3-0.4-0.4-0.40.40.40.50.3-0.10.30.4-1.0
Progressive ratio test 2 active lever presses0.80.82.50.90.81.0-0.8-0.8-0.40.80.81.0-0.6-0.6-0.60.60.60.71.3-1.00.81.3-1.6
Progressive ratio test 2 breakpoint0.70.82.70.90.80.9-0.8-0.8-0.30.80.81.0-0.6-0.6-0.60.60.60.71.3-1.10.81.4-1.7
Progressive ratio test 2 inactive lever presses0.60.72.50.50.70.9-0.5-0.5-0.30.80.81.0-0.5-0.5-0.50.50.50.61.3-1.01.11.5-1.6
Incentive Sensitization - Responses3.23.36.31.71.71.9-1.5-1.5-1.31.81.82.0-1.6-1.6-1.61.61.61.82.2-2.01.82.2-2.5
Incentive Sensitization - Breakpoint3.83.87.01.91.92.1-1.7-1.7-1.41.91.92.2-1.7-1.7-1.71.71.71.92.4-2.12.02.4-2.6
Sum of active levers in priming session hrs 5-60.30.30.50.60.50.5-0.3-0.3-0.60.70.70.5-0.7-0.7-0.70.70.60.70.5-0.70.30.3-0.3
Progressive ratio0.40.41.1-0.5-0.6-0.60.40.41.0-0.6-0.6-0.60.90.90.9-0.9-0.7-0.7-0.30.4-0.7-0.1-0.3
Food seeking constrained by brief footshock0.70.91.40.91.11.1-0.9-0.9-0.90.81.21.0-0.9-0.9-0.90.91.01.01.1-1.10.80.80.1
Seeking ratio, punishment vs. effort0.81.01.40.81.01.1-0.7-0.7-1.21.01.11.0-1.2-1.2-1.21.21.11.10.9-1.01.10.7-0.0
Retroperitoneal fat weight1.03.34.12.01.72.0-1.3-1.3-2.02.01.71.9-2.0-2.0-2.02.01.91.91.7-1.81.81.5-1.2
Reaction time number correct1.21.72.4-1.4-1.5-1.51.41.41.1-1.2-1.4-1.51.11.11.1-1.1-1.1-1.2-1.51.4-1.4-1.40.4
Reaction time mean minus median0.10.10.50.30.1-0.2-0.7-0.70.2-0.0-0.2-0.20.20.20.2-0.2-0.1-0.2-0.0-0.1-0.40.0-0.1
Reaction time mean minus median AUC0.30.31.50.90.60.3-1.2-1.2-0.40.70.40.2-0.4-0.4-0.40.40.40.40.3-0.50.10.3-0.7
Reaction time num false alarms0.60.92.3-0.5-0.6-1.2-0.2-0.20.8-1.0-0.9-1.20.90.90.9-0.9-0.9-1.0-1.00.8-1.5-1.21.3
Reaction time num false alarms AUC0.30.41.8-0.3-0.4-0.9-0.2-0.20.5-0.7-0.6-0.90.50.50.5-0.5-0.6-0.7-0.60.5-1.3-0.90.9
Reaction time trials correct on left1.21.72.4-1.4-1.5-1.51.41.41.1-1.2-1.4-1.51.11.11.1-1.1-1.1-1.2-1.51.4-1.4-1.40.4
Reaction time trials on left1.21.82.5-1.5-1.5-1.61.41.41.1-1.3-1.5-1.51.21.21.2-1.2-1.2-1.2-1.61.4-1.4-1.50.4
Reaction time mean0.40.51.2-0.4-0.6-0.60.30.31.1-0.8-0.7-0.80.90.90.9-0.9-1.0-0.9-0.50.5-0.9-0.30.3
Reaction time mean AUC0.40.51.2-0.4-0.6-0.60.30.31.1-0.7-0.7-0.71.01.01.0-1.0-1.0-0.9-0.50.5-0.8-0.20.3
Median of all reaction times0.50.71.7-0.6-0.7-0.70.60.61.3-0.9-0.7-0.81.11.11.1-1.1-1.2-1.0-0.50.6-0.8-0.20.2
Reaction time omissions0.91.32.1-0.9-1.1-1.50.50.51.3-1.0-1.3-1.41.21.21.2-1.2-1.2-1.2-1.11.0-1.4-0.90.1
Reaction time false alarm rate0.10.10.60.30.3-0.2-0.8-0.80.0-0.1-0.0-0.20.00.00.0-0.0-0.1-0.10.0-0.1-0.6-0.20.7
Reaction time premature initiation rate0.81.15.30.70.71.0-0.3-0.3-0.51.10.91.0-0.9-0.9-0.90.90.90.91.3-1.21.11.6-2.3
Reaction time premature initiations0.20.33.70.0-0.00.20.30.30.00.40.20.2-0.3-0.3-0.30.30.30.30.5-0.40.40.8-1.9
Std. dev. reaction times0.10.10.30.20.0-0.2-0.5-0.50.4-0.2-0.2-0.20.30.30.3-0.3-0.3-0.3-0.0-0.0-0.50.00.2
Reaction time trials completed1.21.82.5-1.5-1.5-1.61.41.41.1-1.3-1.5-1.51.21.21.2-1.2-1.2-1.2-1.61.4-1.4-1.50.4
Reaction time trials AUC0.91.21.8-1.2-1.3-1.31.21.20.8-1.0-1.2-1.30.90.90.9-0.9-0.9-1.0-1.41.2-1.2-1.30.3
Run reversals in cocaine runway, females2.32.24.3-1.6-1.5-1.21.51.50.9-1.6-1.3-1.31.31.31.3-1.3-1.3-1.4-1.81.6-1.5-2.12.0
Run reversals in cocaine runway, males0.30.31.10.80.60.3-1.1-1.1-0.50.60.30.2-0.4-0.4-0.40.40.40.40.3-0.50.30.20.5
Latency to leave start box in cocaine runway1.51.62.41.21.31.5-0.9-0.9-1.41.31.51.6-1.3-1.3-1.31.31.31.41.4-1.41.41.2-0.5
Latency to leave start box in cocaine runway, F0.40.51.20.40.60.7-0.3-0.3-0.70.70.70.8-0.7-0.7-0.70.70.70.70.9-1.10.50.7-0.3
Latency to leave start box in cocaine runway, M1.91.82.91.41.51.6-1.3-1.3-1.31.41.51.5-1.3-1.3-1.31.31.21.31.4-1.11.71.4-0.8
Std. dev. time between licks in bursts0.50.61.1-0.9-0.9-0.71.11.10.8-0.7-0.8-0.70.80.80.8-0.8-0.8-0.8-0.60.7-0.5-0.30.2
Total sessions with >9 infusions0.10.10.90.30.30.1-0.4-0.4-0.30.00.20.0-0.1-0.1-0.10.10.10.1-0.10.1-0.3-0.41.0
Short access day 1 total inactive lever presses3.43.84.32.02.12.1-2.1-2.1-1.91.81.91.9-2.0-2.0-2.02.02.01.92.0-1.91.91.9-1.4
Short access day 10 total inactive lever presses4.44.96.22.32.42.4-2.1-2.1-2.22.22.32.4-2.2-2.2-2.22.22.22.22.3-2.02.52.2-1.6
Short access day 1 total infusions1.31.32.01.11.41.3-1.4-1.4-1.10.91.41.2-1.2-1.2-1.21.21.10.91.2-1.11.11.1-0.2
Short access day 10 total infusions0.30.30.5-0.4-0.4-0.50.30.30.6-0.5-0.5-0.50.60.60.6-0.6-0.7-0.7-0.50.6-0.7-0.60.6
Short access total infusions0.50.61.20.91.00.9-1.1-1.1-0.70.70.90.8-0.6-0.6-0.60.60.60.60.8-0.70.60.6-0.0
Short access day 1 locomotion0.10.10.40.10.30.4-0.1-0.1-0.3-0.00.30.4-0.3-0.3-0.30.30.20.10.4-0.20.10.20.6
Short access day 10 total locomotion0.70.81.6-1.0-0.9-1.00.90.90.6-1.0-0.8-1.00.70.70.7-0.7-0.7-0.7-1.00.9-1.2-1.20.8
Short access total locomotion0.10.10.4-0.2-0.1-0.20.10.10.0-0.3-0.1-0.30.10.10.1-0.1-0.2-0.2-0.30.3-0.6-0.50.6
One hour access (0.3 mA shock)0.00.00.10.20.20.2-0.1-0.10.10.10.20.20.20.20.2-0.2-0.2-0.00.1-0.1-0.0-0.00.3
Compulsive drug intake0.10.10.90.10.10.30.30.30.10.20.10.3-0.1-0.1-0.10.10.20.20.6-0.30.50.9-0.9
One hour access (shock baseline)0.30.31.8-0.2-0.2-0.3-0.0-0.00.2-0.4-0.3-0.40.60.60.6-0.6-0.6-0.5-0.70.5-0.7-1.11.3
Social response proportion0.30.30.50.40.50.6-0.2-0.2-0.70.60.70.6-0.7-0.7-0.70.70.60.60.5-0.60.40.3-0.4
Social responses0.10.10.3-0.1-0.10.20.50.5-0.40.30.10.4-0.4-0.4-0.40.40.40.40.1-0.10.40.20.3
Social time2.33.04.9-2.2-2.2-2.02.02.01.9-1.9-2.1-1.81.61.61.6-1.6-1.6-1.7-1.51.8-1.3-0.8-0.2
Soleus weight0.20.51.40.80.70.6-0.6-0.6-0.40.90.60.6-0.7-0.7-0.70.70.60.61.1-1.00.61.2-0.4
Bone: stiffness0.10.20.80.60.3-0.2-0.9-0.90.40.1-0.1-0.10.10.10.1-0.1-0.0-0.30.3-0.3-0.30.5-0.8
Tibialis anterior weight0.00.10.5-0.4-0.30.00.70.7-0.0-0.10.0-0.0-0.0-0.0-0.00.00.0-0.00.00.1-0.1-0.10.1
Time to tail flick, vehicle, before self-admin0.20.20.30.20.20.2-0.4-0.4-0.50.40.30.3-0.6-0.6-0.60.60.50.50.3-0.50.20.3-0.1
Time to tail flick, vehicle, after self-admin0.20.20.6-0.4-0.5-0.50.50.50.2-0.3-0.6-0.50.30.30.3-0.3-0.3-0.3-0.70.4-0.3-0.70.8
Time to tail flick, test, before self-admin0.10.11.10.10.10.10.10.1-0.30.10.10.1-0.2-0.2-0.20.20.20.1-0.00.20.50.11.0
Time to tail flick, test, after self-admin1.41.42.0-1.4-1.3-1.21.31.31.1-1.4-1.2-1.21.11.11.1-1.1-1.1-1.0-1.31.2-1.1-1.10.6
Delta time to tail flick, vehicle, before/after SA0.20.20.60.60.50.6-0.3-0.3-0.20.40.40.5-0.3-0.3-0.30.30.30.20.6-0.40.60.7-0.8
Delta time to tail flick, test, before/after SA0.90.81.3-1.1-1.0-0.91.01.01.0-1.1-0.9-0.90.90.90.9-0.9-0.9-0.8-0.80.7-1.0-0.7-0.3
Tibia length0.30.92.21.31.20.8-1.5-1.5-0.80.91.00.7-0.8-0.8-0.80.80.80.80.9-0.90.70.8-0.6
Ambulatory time before self-admin0.10.10.60.10.10.20.00.00.10.20.20.2-0.1-0.1-0.10.10.10.00.5-0.40.40.7-0.8
Ambulatory time after self-admin0.40.51.10.50.60.8-0.3-0.3-0.60.50.70.7-0.6-0.6-0.60.60.70.70.8-0.51.11.0-0.4
Bone: tissue strength0.40.41.50.80.60.6-0.8-0.8-0.30.60.40.7-0.4-0.4-0.40.40.50.50.6-0.51.00.8-1.2
Total heroin consumption0.60.71.10.90.80.7-0.8-0.8-0.60.90.80.7-0.8-0.8-0.80.80.80.70.9-0.90.80.9-1.1
Bone: trabecular number0.71.12.1-0.9-0.9-1.20.70.70.8-1.2-1.0-1.31.01.01.0-1.0-1.0-1.2-1.21.1-1.5-1.41.0
Bone: trabecular spacing1.72.23.21.41.31.6-0.9-0.9-1.51.81.51.6-1.5-1.5-1.51.51.61.81.5-1.51.81.5-0.9
Bone: trabecular thickness0.20.20.8-0.6-0.4-0.30.90.90.1-0.6-0.2-0.30.20.20.2-0.2-0.2-0.2-0.20.3-0.6-0.40.3
Bone: trabecular tissue density0.20.30.9-0.7-0.6-0.50.80.80.6-0.5-0.5-0.30.40.40.4-0.4-0.5-0.5-0.00.2-0.60.1-1.0
Water consumed over 24 hours3.03.75.72.22.11.9-2.4-2.4-1.71.91.81.8-1.8-1.8-1.81.81.81.61.9-1.91.81.9-1.7
Number of responses in last shaping day0.50.51.2-1.1-0.8-0.60.90.90.8-0.9-0.7-0.70.60.60.6-0.6-0.6-0.7-0.40.6-0.4-0.10.3