Hub : Genes

Pacsin1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Pacsin1 0.78 0.09 0.0e+00 0.4 0.38 0.42 0.42 8.5e-23 4.2e-21 6.9e-24 3.2e-24
2 IC gene expression Pacsin1 0.18 0.08 8.8e-06 0.12 0.11 0.1 0.12 1.0e-05 2.0e-05 5.1e-05 1.5e-05
3 pVTA gene expression Pacsin1 0.19 0.07 3.7e-07 0.09 0.08 0.07 0.1 9.7e-08 4.0e-07 1.5e-06 4.6e-08
4 NAcc gene expression Pacsin1 0.09 0.05 1.8e-07 0.06 0.05 0.06 0.06 2.0e-09 2.7e-08 9.2e-09 4.0e-09
5 Brain gene expression Pacsin1 0.42 0.11 1.9e-14 0.16 0.14 0.15 0.17 3.1e-15 4.3e-13 4.8e-14 2.8e-15
6 OFC gene expression Pacsin1 0.49 0.22 1.8e-04 0.08 0.18 0.17 0.18 6.1e-03 4.2e-05 6.2e-05 5.3e-05
7 IL gene expression Pacsin1 0.47 0.13 2.8e-07 0.16 0.1 0.09 0.12 9.7e-05 2.3e-03 3.4e-03 8.6e-04
8 PL gene expression Pacsin1 0.24 0.09 0.0e+00 0.19 0.22 0.21 0.2 9.1e-21 6.1e-24 5.4e-23 1.4e-21
9 NAcc mRNA stability Pacsin1 0.03 0.02 3.0e-03 0.01 0.02 0.02 0.01 3.2e-03 5.8e-04 1.4e-03 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.30.60.3-0.80.5-0.40.20.8-0.40.10.7
Area under the delay curve0.40.61.9-0.60.4-0.20.6-0.4-0.60.9-1.0-1.4
BMI with tail1.65.59.63.0-1.61.8-2.52.53.1-2.12.41.5
BMI without tail0.31.43.11.8-0.10.3-1.41.21.4-0.71.70.5
Body weight0.94.06.9-1.52.5-2.62.4-2.0-0.92.3-1.3-1.8
Weight adjusted by age1.54.26.6-2.21.5-1.52.4-1.9-2.12.4-1.8-2.6
Bone surface0.50.91.8-1.01.1-1.31.0-1.4-0.60.9-0.60.2
Bone volume0.10.10.3-0.40.3-0.50.5-0.60.00.3-0.30.2
Breakpoint value in progressive ratio session0.30.62.20.90.1-0.2-0.50.11.5-0.50.51.3
Number of licking bursts0.20.51.7-0.61.2-1.30.4-0.7-0.50.4-0.20.4
Context. condit. distance diff. score1.62.03.2-1.71.5-1.51.5-1.5-1.31.1-1.8-0.2
Locomotion velocity, session 11.31.43.6-1.40.7-0.80.9-1.1-1.91.0-1.4-1.3
Locomotion distance, session 10.60.81.30.6-1.11.0-1.10.9-0.0-1.10.80.6
Locomotion velocity, session 20.40.50.8-0.90.7-0.70.8-0.9-0.70.4-0.40.2
Locomotion distance, session 20.10.20.6-0.2-0.60.8-0.10.2-0.3-0.5-0.10.1
Locomotion velocity, session 30.30.30.70.6-0.40.4-0.80.70.1-0.60.80.5
Locomotion distance, session 30.50.61.40.7-0.60.9-1.21.00.1-1.00.50.4
Stereotopy head waving bouts, day 32.12.54.5-1.32.0-2.11.5-1.8-1.31.7-1.1-0.7
Stereotopy head waving duration, day 31.31.62.2-1.31.1-1.41.3-1.4-1.51.4-1.0-1.1
Locomotion velocity, session 70.20.20.8-0.3-0.70.4-0.10.1-0.20.2-0.9-0.5
Locomotion distance, session 70.30.40.9-0.6-0.80.90.10.4-0.6-0.3-1.0-0.6
Stereotopy head waving bouts, day 70.00.10.20.20.1-0.1-0.40.0-0.40.20.2-0.3
Stereotopy head waving duration, day 70.10.10.20.40.3-0.3-0.5-0.1-0.10.30.4-0.1
Locomotion velocity, session 85.06.18.0-2.82.6-2.52.7-2.8-2.42.4-2.4-1.2
Locomotion distance, session 80.50.71.7-1.30.7-0.50.9-0.8-1.00.2-1.20.2
Degree of sensitization distance1.31.43.1-1.51.0-1.11.8-1.3-0.71.2-1.2-0.5
Degree of sensitization stereotypy0.50.61.40.9-0.60.8-1.20.80.2-0.70.70.4
Conditioned locomotion0.50.62.2-0.90.7-0.61.5-0.80.40.5-0.30.4
Cocaine response after cond. corrected0.40.61.70.8-0.3-0.1-0.50.11.3-0.30.81.3
Cocaine response after cond. not corrected0.20.41.2-0.10.8-1.10.3-0.70.20.60.30.6
Cocaine response before conditioning2.83.35.5-1.82.2-2.11.6-1.5-2.41.8-1.1-1.6
Saline control response0.91.32.21.5-1.30.9-1.11.01.3-0.81.50.3
Bone: connectivity density0.10.10.3-0.30.0-0.30.3-0.50.30.4-0.30.4
Bone: cortical apparent density1.52.33.51.9-1.31.4-1.71.61.6-1.51.60.9
Bone: cortical area0.00.10.10.20.3-0.3-0.2-0.0-0.10.20.40.2
Bone: cortical porosity0.50.61.8-0.9-0.50.50.50.0-1.30.3-0.6-1.2
Bone: cortical porosity1.71.93.9-1.70.4-0.31.3-0.8-2.01.2-1.5-1.9
Bone: cortical thickness3.96.59.92.9-2.42.7-3.12.92.0-2.42.71.6
Bone: cortical thickness5.16.37.62.7-2.32.5-2.62.62.6-2.42.82.0
Bone: cortical tissue density1.01.72.51.6-1.11.2-1.41.31.3-1.21.40.7
Condit. Reinf. active minus inactive responses0.40.51.2-0.8-0.00.40.6-0.4-1.00.5-0.8-1.1
Condit. Reinf. active-inactive response ratio0.10.10.30.2-0.20.5-0.10.20.1-0.10.2-0.2
Condit. Reinf. active responses0.20.20.6-0.4-0.10.50.3-0.0-0.40.4-0.6-0.8
Condit. Reinf. inactive responses0.30.40.80.5-0.70.8-0.60.90.6-0.70.10.3
Incentive salience index mean0.81.11.8-1.30.7-0.51.1-1.0-1.21.1-1.3-0.9
Condit. Reinf. lever presses1.01.62.3-1.41.3-1.31.2-1.5-0.81.4-1.5-0.3
Condit. Reinf. active minus inactive responses0.60.92.4-1.20.4-0.41.1-0.7-1.50.8-0.8-1.2
Condit. Reinf. active-inactive response ratio0.71.12.1-1.11.0-0.81.1-0.8-1.41.0-0.9-1.2
Condit. Reinf. active responses0.30.51.4-1.00.00.00.8-0.3-1.20.3-0.6-0.7
Condit. Reinf. inactive responses0.10.20.40.1-0.70.6-0.00.40.2-0.70.40.4
Condit. Reinf. lever presses0.30.51.6-0.8-0.60.60.4-0.0-1.30.1-0.5-0.8
Condit. Reinf. lever reinforcers received0.40.51.9-1.00.00.10.8-0.3-1.40.3-0.6-0.8
Conditioned reinforcement - actives0.10.41.1-0.7-0.10.10.7-0.2-0.40.7-1.1-1.0
Conditioned reinforcement - inactives0.10.30.9-0.4-0.50.50.20.1-0.80.3-0.3-0.9
Conditioned locomotion1.52.33.6-1.80.6-0.71.9-1.3-1.11.8-1.8-1.9
Patch foraging indifference point 0 sec0.61.73.11.6-1.31.4-1.41.71.0-1.31.40.3
Patch foraging indifference point AUC0.61.53.1-1.11.6-1.70.9-1.3-1.61.1-0.4-0.4
Delay disc. indifference point, 0s delay0.40.40.9-0.50.7-0.30.5-0.5-0.50.6-0.9-0.8
Delay disc. indifference point, 16s delay0.30.41.40.2-1.21.1-0.30.8-0.1-0.2-0.0-0.7
Delay disc. indifference point, 2s delay1.92.13.5-1.41.0-1.11.4-1.2-1.41.6-1.6-1.9
Delay disc. indifference point, 24s delay0.30.62.7-0.4-0.60.80.40.4-0.50.4-0.6-1.6
Delay disc. indifference point, 4s delay0.70.82.0-0.51.4-0.90.6-0.7-0.50.8-0.9-1.1
Delay disc. indifference point, 8s delay0.40.61.5-0.80.3-0.20.8-0.5-0.51.0-1.0-1.2
Indifference point function ln k0.00.10.2-0.0-0.10.3-0.20.30.0-0.4-0.10.3
Indifference point function log k0.00.10.2-0.0-0.10.3-0.20.30.0-0.4-0.10.3
Patch foraging total patch changes 0 sec0.82.33.91.8-1.51.6-1.62.01.1-1.41.60.4
Patch foraging total patch changes 12 sec0.70.92.11.2-0.70.5-1.21.10.5-1.01.40.6
Patch foraging total patch changes 18 sec1.43.34.42.1-1.81.7-1.91.91.7-1.82.11.4
Patch foraging total patch changes 24 sec1.03.56.01.8-2.52.3-1.92.11.3-2.01.70.8
Patch foraging total patch changes 6 sec1.62.74.21.8-2.01.8-1.72.11.1-1.71.60.3
Patch foraging time to switch 0 sec0.93.37.41.9-2.01.8-1.41.52.7-1.61.51.4
Patch foraging water rate 0 sec0.10.41.2-0.50.5-0.50.2-0.1-1.10.6-0.5-1.0
Patch foraging water rate 12 sec0.41.72.61.2-1.41.6-1.51.60.7-1.51.10.8
Patch foraging water rate 18 sec0.10.20.5-0.00.5-0.40.00.1-0.10.7-0.3-0.7
Patch foraging water rate 24 sec0.50.81.61.0-0.20.6-1.21.30.5-1.00.80.5
Patch foraging water rate 6 sec0.40.60.90.7-0.70.7-0.90.90.3-1.00.90.6
Seeking ratio, delayed vs. immediate footshock0.50.71.61.00.6-0.7-0.70.10.7-0.51.21.3
Distance traveled before self-admin0.20.41.30.20.9-1.10.0-0.60.40.00.20.9
Distance traveled after self-admin0.40.73.40.11.2-1.80.4-0.90.20.40.30.8
Extensor digitorum longus weight1.03.85.3-2.31.8-1.92.2-2.3-2.11.7-2.0-1.2
Bone: elastic displacement0.40.51.40.0-1.21.1-0.40.5-0.6-0.1-0.1-1.1
Bone: elastic work0.10.20.60.1-0.60.7-0.20.3-0.1-0.0-0.0-0.8
Bone: endosteal estimation5.112.621.3-3.34.4-4.64.0-4.0-2.33.7-2.8-1.9
Bone: endosteal perimeter2.76.611.9-2.43.3-3.52.9-3.0-1.42.7-2.0-0.7
Epididymis fat weight9.045.256.37.5-6.97.0-7.17.57.0-6.36.64.0
Delta time in closed arm before/after self-admin0.40.41.20.3-0.81.1-0.20.60.8-0.20.4-0.1
Delta time in open arm before/after self-admin0.70.83.0-0.51.5-1.70.5-0.6-0.60.5-0.8-0.5
Diff in mean of infusions in LGA sessions0.50.92.01.0-0.80.6-0.90.61.4-0.90.61.3
Delay discount exponential model param0.40.62.00.6-0.40.2-0.70.40.6-0.91.11.4
Extinction: sum of active levers before priming0.20.30.50.5-0.50.5-0.60.40.5-0.60.40.7
Active lever presses in extinction session 60.30.31.0-0.2-1.01.00.20.30.20.2-0.3-0.8
Bone: final force0.81.23.01.4-0.50.7-0.91.21.7-1.11.30.7
Bone: final moment0.30.51.51.0-0.20.3-0.60.91.2-0.70.70.2
Food consumed during 24 hour testing period0.20.51.1-0.30.5-0.90.9-1.00.70.8-0.00.5
Glucose5.89.110.8-3.33.2-2.73.0-3.0-3.33.0-3.2-2.6
Heart weight1.11.75.9-1.3-0.1-0.10.8-0.3-2.31.1-1.0-2.4
Delay discount hyperbolic model param0.50.72.00.7-0.40.3-0.70.50.8-0.91.11.4
Intermittent access intake day 1-15 change0.10.51.30.80.0-0.4-0.60.21.2-0.40.71.1
Intermittent access intake escalation0.10.61.61.0-0.40.1-0.70.51.3-0.50.80.9
Intermittent access intake escalation 20.50.92.3-0.70.9-1.50.9-1.1-0.41.0-1.0-0.5
Intermitt. access day 1 inactive lever presses0.11.13.21.10.9-0.1-1.30.30.4-1.21.31.8
Intermitt. access day 15 inactive lever presses0.00.20.7-0.10.9-0.70.2-0.5-0.30.2-0.00.1
Intermitt. access escalation Index0.61.95.01.60.10.2-1.70.71.4-1.61.32.2
Intermittent access day 1 total infusions0.72.04.8-1.7-0.40.51.3-0.5-1.61.3-2.0-2.2
Intermittent access day 15 total infusions0.10.20.5-0.4-0.60.30.30.1-0.30.4-0.5-0.7
Intermittent access terminal intake (last 3 days)0.20.41.2-0.5-0.90.40.40.1-0.60.5-0.6-1.1
Intermittent access total infusions0.80.92.5-1.1-0.40.20.9-0.3-1.10.9-1.2-1.6
Intermittent access day 1 locomotion0.30.51.0-0.80.1-0.10.7-0.5-0.80.6-1.0-1.0
Intermittent access day 15 total locomotion0.31.11.8-0.90.9-0.91.3-1.1-0.31.3-1.1-1.2
Intermittent access total locomotion1.41.72.6-1.40.4-1.01.5-1.2-1.11.5-1.5-1.6
Intermittent access standard deviation0.10.61.21.0-0.70.3-0.60.81.0-0.61.10.6
Left kidney weight0.10.61.3-0.50.9-1.11.1-0.7-0.30.8-0.3-0.8
Right kidney weight0.32.04.3-1.01.7-2.11.8-1.6-0.31.5-0.8-0.9
Cocaine induced anxiety0.20.62.30.01.3-1.50.0-0.8-0.20.00.10.8
Post-drug Anxiety0.20.20.80.40.4-0.9-0.3-0.20.1-0.10.40.7
Baseline Anxiety1.01.74.31.1-2.11.8-1.11.51.3-0.80.90.4
Tail length3.116.623.9-4.04.9-4.84.2-4.3-4.14.1-3.0-2.9
Length with tail6.428.235.7-5.55.7-5.86.0-5.6-5.05.5-4.4-4.1
Length without tail2.010.316.0-3.43.0-3.24.0-3.3-2.43.4-3.0-2.9
Times rat made contact with spout1.51.74.11.2-2.01.7-1.51.30.7-1.31.00.4
Lifetime Intake0.81.02.7-1.1-0.20.21.0-0.4-1.11.0-1.2-1.6
Liver weight, left3.45.912.4-1.93.5-3.22.4-2.9-1.42.6-1.7-0.8
Liver weight, right7.813.522.9-3.54.8-4.33.9-4.1-3.23.5-3.1-2.0
Locomotor activity0.40.62.10.61.5-1.2-0.5-0.00.0-0.00.80.7
Locomotor testing distance0.71.73.21.80.2-0.1-1.60.91.5-0.91.71.7
Locomotor testing rearing0.20.71.31.00.8-0.7-0.60.21.1-0.30.91.2
Locomotion in novel chamber0.00.10.3-0.10.50.2-0.0-0.0-0.10.0-0.4-0.4
Locomotion in novel chamber post-restriction0.10.21.20.6-0.2-0.3-0.30.11.1-0.20.60.1
Fecal boli incidents, locomotor time 10.10.30.8-0.5-0.20.10.7-0.30.20.7-0.9-0.6
Change in fecal boli incidents, locomotor task0.10.10.50.30.4-0.4-0.1-0.00.2-0.10.70.4
Time >=10cm from walls, locomotor time 10.81.03.30.61.8-1.20.1-0.71.30.20.51.2
Bouts of movement, locomotor time 10.30.31.10.10.8-1.1-0.0-0.50.20.00.20.9
Total resting periods, locomotor time 10.50.62.2-0.41.1-1.50.5-1.0-0.20.5-0.30.5
Rest time, locomotor task time 10.81.32.2-1.50.9-1.01.2-1.0-1.30.9-1.3-0.9
Distance moved, locomotor task time 10.10.40.90.9-0.30.5-0.60.50.8-0.50.90.4
Vertical activity count, locomotor time 10.10.51.71.1-0.10.3-0.40.21.3-0.21.00.7
Time >=10cm from walls, locomotor time 20.10.41.2-0.11.1-0.30.6-0.50.70.8-0.3-0.7
Bouts of movement, locomotor time 20.51.84.8-0.82.2-2.01.0-1.8-0.91.0-0.50.0
Total resting periods, locomotor time 20.52.25.5-1.12.4-2.11.2-2.0-1.21.1-0.7-0.1
Rest time, locomotor task time 20.81.44.3-0.82.1-1.90.8-1.4-0.60.6-0.80.3
Distance moved, locomotor task time 20.50.62.40.3-1.51.30.10.60.70.30.2-0.8
Vertical activity count, locomotor time 20.20.40.9-0.2-1.00.80.50.00.30.7-0.3-1.0
Light reinforcement 10.62.66.21.9-0.60.2-1.40.42.5-1.12.02.5
Light reinforcement 20.20.30.8-0.10.5-0.60.6-0.80.90.20.00.8
Bone: marrow area5.012.321.2-3.24.4-4.63.9-3.9-2.33.7-2.8-1.9
Bone: maximum diameter2.75.58.3-2.42.7-2.92.4-2.7-2.02.5-1.9-1.0
Bone: maximum force0.00.10.20.30.3-0.2-0.10.30.4-0.20.2-0.1
Bone: maximum moment0.10.20.6-0.20.7-0.50.3-0.1-0.20.3-0.3-0.8
Mean time between licks in bursts0.95.510.0-3.22.1-2.12.9-2.5-2.71.7-2.1-0.7
Mean num. licks in bursts0.61.74.31.2-2.12.0-1.31.30.7-1.00.7-0.2
Cd content in liver0.30.41.1-0.0-1.10.80.2-0.00.50.4-0.6-0.7
Co content in liver1.01.22.71.3-1.31.2-0.81.21.7-0.50.80.2
Cu content in liver4.04.76.72.3-2.52.3-2.62.31.8-2.22.01.3
Fe content in liver0.20.31.00.1-0.51.00.10.70.3-0.90.0-0.0
K content in liver0.50.51.5-1.2-0.10.00.9-0.6-1.00.1-0.7-0.1
Mg content in liver1.51.63.5-1.91.2-1.21.6-1.3-1.50.8-0.90.2
Mn content in liver5.25.99.9-3.12.6-2.13.1-2.3-2.71.5-2.5-1.0
Na content in liver0.91.01.40.9-1.01.1-1.01.00.6-1.11.21.1
Rb content in liver0.20.30.5-0.50.5-0.40.6-0.6-0.10.6-0.7-0.4
Se content in liver4.04.89.6-2.82.3-1.82.4-2.0-3.11.3-1.9-1.2
Sr content in liver0.60.51.4-0.60.1-0.10.7-0.6-0.31.0-1.0-1.2
Zn content in liver1.51.83.1-1.80.6-0.71.6-1.4-1.71.1-1.4-1.3
Bone: minimum diameter2.14.16.6-1.92.5-2.62.2-2.4-1.22.3-1.5-0.7
Time in familiar zone, hab. session 10.91.02.40.7-1.51.5-0.91.30.6-1.10.30.1
Time in novel zone, hab. session 10.50.61.7-0.31.3-1.10.4-0.9-0.50.9-0.2-0.4
Total zone transitions, hab. session 11.21.73.71.4-1.01.1-1.91.40.5-1.41.51.1
Total locomotion distance, hab. session 10.71.01.50.7-1.00.8-1.20.90.2-1.21.11.2
Locomotion velocity, hab. session 10.50.81.30.4-1.10.8-0.90.8-0.1-1.11.01.0
Time in familiar zone, hab. session 20.91.02.90.8-0.20.3-0.70.70.9-1.31.41.7
Time in novel zone, hab. session 21.21.34.2-0.80.3-0.50.8-0.8-0.91.5-1.5-2.0
Total zone transitions, hab. session 21.21.53.01.3-0.30.5-1.51.01.0-1.31.61.7
Total locomotion distance, hab. session 21.62.14.91.3-0.80.8-1.71.11.0-1.71.72.2
Locomotion velocity, hab. session 21.41.94.61.1-0.80.9-1.51.10.8-1.71.62.1
Novel to familiar place preference ratio0.30.41.00.5-0.81.0-0.60.70.2-0.60.1-0.3
Novelty place preference0.10.20.50.3-0.60.7-0.40.5-0.0-0.40.0-0.4
Time in novel zone, NPP test0.10.10.30.1-0.40.5-0.30.3-0.2-0.2-0.2-0.5
Total zone transitions, NPP test0.20.20.50.1-0.60.5-0.50.3-0.2-0.70.40.7
Total locomotion distance, NPP test0.40.51.20.3-1.11.1-0.60.70.3-0.90.30.5
Locomotion velocity, NPP test0.91.22.10.7-1.41.4-1.11.10.7-1.40.81.1
Intraocular pressure0.00.00.1-0.2-0.0-0.10.3-0.10.10.1-0.4-0.1
Delta distance traveled before/after self-admin0.40.40.7-0.50.5-0.80.7-0.5-0.60.7-0.4-0.9
Delta ambulatory time before/after self-admin0.20.41.2-0.40.8-1.10.6-0.6-0.50.6-0.3-0.5
Parametrial fat weight0.51.25.01.50.1-0.5-0.70.32.2-0.41.11.3
Pavlov. Cond. lever latency2.43.06.22.2-1.31.0-1.51.42.5-1.52.21.6
Pavlov. Cond. magazine entry latency2.93.77.0-2.21.9-1.91.7-1.8-2.61.8-1.8-1.2
Pavlov. Cond. change in total contacts1.41.52.6-1.21.3-1.00.9-1.0-1.61.3-1.2-1.1
Pavlov. Cond. index score3.13.97.5-2.41.8-1.51.8-1.7-2.71.8-2.2-1.6
Pavlov. Cond. latency score2.93.76.9-2.41.7-1.41.8-1.7-2.61.7-2.2-1.5
Pavlov. Cond. lever contacts2.12.64.3-1.91.3-1.11.4-1.4-2.11.6-2.0-1.4
Pavlov. Cond. magazine entry number1.62.14.91.6-1.51.4-1.11.22.2-1.31.30.9
Pavlov. Cond. intertrial magazine entries1.31.64.11.0-2.01.8-1.01.31.2-1.00.90.1
Pavlov. Cond. lever-magazine prob. diff.2.83.57.0-2.21.6-1.41.6-1.5-2.61.7-2.1-1.6
Pavlov. Cond. response bias3.03.77.5-2.21.9-1.81.6-1.7-2.71.8-2.0-1.4
Pavlov. Cond. lever latency0.40.51.30.51.1-1.1-0.0-0.41.00.20.30.8
Pavlov. Cond. magazine entry latency1.42.02.8-1.51.0-1.11.7-1.5-1.11.6-1.7-1.2
Pavlov. Cond. change in total contacts0.10.30.7-0.5-0.70.70.3-0.0-0.80.1-0.4-0.7
Pavlov. Cond. index score0.71.01.8-1.30.1-0.01.1-0.8-1.31.0-1.2-1.3
Pavlov. Cond. latency score0.60.91.5-1.20.00.01.0-0.8-1.20.9-1.1-1.2
Pavlov. Cond. lever contacts0.30.51.4-0.2-1.21.2-0.10.5-0.7-0.4-0.1-0.6
Pavlov. Cond. magazine entry number0.30.50.90.7-0.30.3-0.80.70.4-0.90.90.7
Pavlov. Cond. intertrial magazine entries0.40.82.0-0.81.4-1.20.8-0.8-0.5-0.00.11.2
Pavlov. Cond. lever-magazine prob. diff.0.60.91.5-1.2-0.00.11.0-0.7-1.20.8-1.2-1.2
Pavlov. Cond. response bias0.50.71.7-1.1-0.40.30.8-0.3-1.30.5-0.9-1.1
Time in closed arm before self-admin0.10.10.3-0.30.3-0.30.3-0.2-0.30.3-0.5-0.5
Time in closed arm after self-admin0.40.51.80.1-1.21.3-0.20.80.2-0.2-0.0-0.6
Time in open arm before self-admin0.20.20.7-0.6-0.80.40.3-0.3-0.70.3-0.2-0.2
Time in open arm after self-admin0.91.02.9-0.91.0-1.70.8-1.0-1.10.8-0.9-0.5
Bone: periosteal estimation1.94.69.0-1.82.9-3.02.2-2.4-1.42.3-1.4-0.9
Bone: periosteal perimeter0.91.73.2-1.21.7-1.81.4-1.5-0.81.5-0.8-0.4
Bone: post-yield work2.33.96.5-1.82.5-2.32.0-2.1-1.32.2-1.9-1.2
Progressive ratio test 1 active lever presses0.30.51.7-0.8-0.30.40.7-0.2-0.60.7-0.9-1.3
Progressive ratio test 1 breakpoint0.30.61.8-0.8-0.30.40.7-0.2-0.70.7-0.9-1.3
Progressive ratio test 1 inactive lever presses0.41.01.81.0-1.31.2-0.81.01.2-0.80.80.6
Progressive ratio test 2 active lever presses0.10.10.3-0.3-0.20.40.10.1-0.10.2-0.4-0.5
Progressive ratio test 2 breakpoint0.10.10.3-0.3-0.20.40.20.1-0.20.2-0.5-0.6
Progressive ratio test 2 inactive lever presses0.41.31.9-1.40.9-0.61.2-1.0-1.31.3-1.3-1.3
Incentive Sensitization - Responses0.00.10.20.30.3-0.0-0.50.10.0-0.40.00.4
Incentive Sensitization - Breakpoint0.10.10.30.40.20.0-0.60.20.2-0.50.10.6
Sum of active levers in priming session hrs 5-60.10.10.2-0.3-0.0-0.10.20.0-0.40.2-0.3-0.4
Progressive ratio0.31.02.11.2-0.20.2-0.61.11.3-1.01.50.8
Food seeking constrained by brief footshock0.20.20.7-0.0-0.70.80.00.30.00.2-0.2-0.8
Seeking ratio, punishment vs. effort0.20.40.9-0.6-0.40.40.1-0.4-0.90.5-0.9-0.8
Retroperitoneal fat weight0.00.10.50.3-0.3-0.2-0.00.00.7-0.20.20.3
Reaction time number correct0.93.34.82.1-1.31.7-1.92.22.1-1.91.71.1
Reaction time mean minus median1.610.313.5-3.63.3-3.43.7-3.7-2.83.2-3.1-1.7
Reaction time mean minus median AUC1.610.915.4-3.92.9-2.83.9-3.5-2.93.3-3.7-2.5
Reaction time num false alarms0.20.40.8-0.70.6-0.90.6-0.7-0.70.10.10.8
Reaction time num false alarms AUC0.20.51.0-0.70.7-1.00.5-0.7-0.90.20.20.7
Reaction time trials correct on left0.93.34.82.1-1.31.7-1.92.22.1-1.91.71.1
Reaction time trials on left0.92.94.32.0-1.11.6-1.82.12.0-1.81.61.0
Reaction time mean3.57.610.1-2.92.7-2.83.2-3.0-2.03.0-3.0-1.8
Reaction time mean AUC3.27.810.3-2.92.8-2.83.2-3.0-2.03.1-3.1-1.9
Median of all reaction times2.64.05.4-2.12.0-2.02.3-2.1-1.32.3-2.3-1.4
Reaction time omissions1.82.96.2-1.42.5-2.41.6-2.0-0.81.6-1.30.0
Reaction time false alarm rate1.62.24.3-1.81.3-1.71.5-1.8-2.11.2-0.8-0.1
Reaction time premature initiation rate0.00.00.10.2-0.30.0-0.2-0.10.1-0.00.10.0
Reaction time premature initiations0.41.21.91.4-1.01.0-1.21.11.4-1.11.10.6
Std. dev. reaction times3.913.016.8-4.03.6-3.74.1-4.0-3.23.8-3.5-2.1
Reaction time trials completed0.92.94.32.0-1.11.6-1.82.12.0-1.81.61.0
Reaction time trials AUC0.93.14.42.1-1.21.6-1.82.12.1-1.81.71.1
Run reversals in cocaine runway, females0.30.31.5-0.2-0.80.50.10.4-0.10.1-0.4-1.2
Run reversals in cocaine runway, males3.64.05.2-2.12.2-2.32.0-2.2-1.92.0-1.8-1.1
Latency to leave start box in cocaine runway0.20.20.60.1-0.80.7-0.30.60.1-0.40.40.4
Latency to leave start box in cocaine runway, F0.20.31.00.1-1.00.8-0.30.60.1-0.40.10.2
Latency to leave start box in cocaine runway, M0.10.10.20.2-0.00.0-0.20.30.1-0.20.50.4
Std. dev. time between licks in bursts2.14.06.6-2.62.1-2.02.3-2.1-2.31.5-1.8-0.7
Total sessions with >9 infusions0.50.61.5-0.90.20.20.8-0.5-0.90.7-0.9-1.2
Short access day 1 total inactive lever presses1.73.54.1-2.01.6-1.71.9-1.9-1.82.0-1.9-1.9
Short access day 10 total inactive lever presses0.53.610.22.20.3-0.0-2.10.91.5-2.02.43.2
Short access day 1 total infusions0.61.22.5-1.30.3-0.21.1-0.7-1.41.1-1.2-1.6
Short access day 10 total infusions0.00.10.3-0.2-0.10.60.10.0-0.20.1-0.3-0.4
Short access total infusions0.50.72.0-0.9-0.10.30.8-0.4-0.80.8-1.0-1.4
Short access day 1 locomotion0.10.20.70.30.10.1-0.40.10.2-0.50.50.8
Short access day 10 total locomotion0.20.62.2-0.11.5-1.40.2-1.0-0.60.20.10.3
Short access total locomotion0.10.20.7-0.20.8-0.50.3-0.6-0.30.2-0.10.1
One hour access (0.3 mA shock)0.10.10.20.0-0.0-0.1-0.40.1-0.3-0.3-0.30.3
Compulsive drug intake0.40.62.40.51.0-0.8-0.6-0.30.5-0.60.31.5
One hour access (shock baseline)0.41.12.9-1.2-0.1-0.10.9-0.5-1.31.0-1.3-1.7
Social response proportion0.20.30.6-0.70.4-0.30.8-0.6-0.70.5-0.3-0.4
Social responses0.10.10.3-0.10.6-0.50.2-0.3-0.1-0.10.50.6
Social time1.62.57.4-0.82.7-2.61.0-1.8-0.40.7-0.11.6
Soleus weight6.920.528.1-4.94.5-4.95.0-5.3-4.34.8-3.8-2.7
Bone: stiffness0.40.71.50.9-0.20.3-0.60.71.2-0.91.11.1
Tibialis anterior weight0.20.51.30.6-1.10.7-0.70.40.4-1.00.70.7
Time to tail flick, vehicle, before self-admin1.21.55.81.30.4-0.4-1.00.31.5-1.01.32.4
Time to tail flick, vehicle, after self-admin0.20.51.0-0.51.0-1.00.6-0.8-0.50.6-0.6-0.2
Time to tail flick, test, before self-admin0.91.11.61.2-0.70.5-1.30.90.7-1.31.11.3
Time to tail flick, test, after self-admin0.20.20.8-0.40.4-0.90.3-0.6-0.50.3-0.50.0
Delta time to tail flick, vehicle, before/after SA0.70.83.0-0.8-0.50.80.6-0.1-0.90.6-1.1-1.7
Delta time to tail flick, test, before/after SA0.00.00.20.10.10.1-0.10.10.5-0.10.10.2
Tibia length2.05.616.9-1.64.1-3.62.2-2.4-0.92.2-1.2-0.4
Ambulatory time before self-admin0.10.20.60.30.3-0.6-0.2-0.20.4-0.20.30.8
Ambulatory time after self-admin0.30.52.40.01.0-1.60.3-0.70.10.30.10.4
Bone: tissue strength0.20.21.20.30.4-0.2-0.20.30.10.1-0.6-1.1
Total heroin consumption0.40.41.60.70.4-0.5-0.6-0.00.6-0.60.71.3
Bone: trabecular number0.40.71.60.6-1.31.0-0.70.50.9-0.70.40.9
Bone: trabecular spacing0.50.71.2-0.61.1-0.90.9-0.8-0.61.0-0.4-1.0
Bone: trabecular thickness0.10.10.2-0.1-0.20.00.3-0.20.50.1-0.40.4
Bone: trabecular tissue density0.71.22.6-1.21.1-0.81.0-0.7-1.60.9-1.1-1.4
Water consumed over 24 hours0.10.31.00.10.5-1.0-0.2-0.7-0.10.9-0.00.0
Number of responses in last shaping day2.12.76.1-2.10.4-0.51.6-1.0-2.51.5-1.6-2.4