Hub : Genes

Pacc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Pacc1 0.32 0.15 2.2e-12 0.16 0.19 0.17 0.18 5.5e-09 1.6e-10 3.1e-09 1.1e-09
2 Brain mRNA stability Pacc1 0.23 0.11 0.0e+00 0.16 0.19 0.16 0.18 4.2e-15 1.8e-17 1.7e-14 2.4e-16
3 Brain gene expression Pacc1 0.1 0.06 5.9e-08 0.06 0.08 0.07 0.07 1.0e-06 8.4e-08 2.3e-07 6.4e-07
4 PL mRNA stability Pacc1 0.18 0.08 0.0e+00 0.2 0.21 0.2 0.21 2.4e-21 3.0e-22 1.1e-21 4.8e-22
5 pVTA gene expression Pacc1 0.31 0.14 5.1e-14 0.17 0.17 0.16 0.17 2.1e-13 1.5e-13 6.5e-13 6.0e-14
6 Adipose alternative TSS NM_001007679.1 0.03 0.02 4.7e-03 0.02 0.02 0.02 0.02 4.3e-03 3.0e-03 4.1e-03 5.2e-03
7 PL gene expression Pacc1 0.36 0.11 0.0e+00 0.38 0.4 0.39 0.4 3.9e-44 2.4e-46 9.7e-46 5.0e-46
8 IC gene expression Pacc1 0.53 0.16 1.7e-14 0.26 0.26 0.25 0.28 1.8e-11 2.0e-11 6.2e-11 2.4e-12
9 PL intron excision ratio chr13_105452038_105456112 0.32 0.15 0.0e+00 0.17 0.18 0.16 0.18 6.6e-18 2.2e-19 1.3e-17 8.6e-19
10 Brain intron excision ratio chr13_105452038_105456112 0.34 0.16 0.0e+00 0.24 0.24 0.22 0.24 1.4e-22 2.9e-22 1.3e-20 5.9e-22
11 IL mRNA stability Pacc1 0.29 0.17 6.2e-04 0.17 0.13 0.09 0.19 7.6e-05 5.3e-04 4.3e-03 3.0e-05
12 IL gene expression Pacc1 0.43 0.19 2.1e-06 0.28 0.24 0.28 0.29 2.5e-07 1.8e-06 2.3e-07 1.3e-07
13 Adipose alternative TSS XM_006250481.5 0.03 0.02 9.9e-03 0.01 0.01 0.01 0.01 7.4e-03 7.5e-03 7.5e-03 9.7e-03
14 OFC mRNA stability Pacc1 0.29 0.15 6.6e-04 0.12 0.07 0.1 0.09 9.7e-04 8.5e-03 2.4e-03 3.8e-03
15 OFC gene expression Pacc1 0.47 0.18 1.6e-06 0.27 0.22 0.25 0.25 4.5e-07 5.3e-06 1.2e-06 1.0e-06
16 BLA gene expression Pacc1 0.23 0.13 4.8e-08 0.13 0.12 0.11 0.12 3.3e-07 1.0e-06 1.5e-06 4.7e-07
17 NAcc gene expression Pacc1 0.4 0.16 0.0e+00 0.18 0.19 0.19 0.2 2.8e-27 6.7e-28 4.7e-28 5.9e-29

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.00.00.2-0.4-0.4-0.3-0.1-0.10.0-0.10.00.1-0.0-0.00.0-0.0-0.00.0-0.00.1
Area under the delay curve0.81.01.5-1.0-1.2-0.9-0.8-0.70.8-1.0-0.5-0.9-1.1-1.0-1.1-0.9-1.2-1.1-0.9-1.1
BMI with tail0.10.20.50.40.50.30.30.3-0.30.50.20.50.60.50.60.70.40.40.30.6
BMI without tail0.41.32.5-1.6-1.4-1.6-1.4-1.31.2-1.1-1.3-0.9-0.9-1.1-0.9-0.8-1.0-1.0-1.0-0.7
Body weight2.310.213.0-3.6-3.6-3.5-3.4-3.33.2-3.1-3.1-3.0-3.1-3.2-3.1-3.1-3.2-3.0-3.0-2.8
Weight adjusted by age0.30.51.1-0.7-1.0-0.8-0.7-0.30.6-0.7-0.4-0.4-0.7-0.4-0.5-0.3-1.0-0.9-0.9-0.6
Bone surface0.00.00.1-0.2-0.3-0.2-0.0-0.0-0.1-0.0-0.00.10.0-0.00.00.00.0-0.1-0.00.2
Bone volume0.10.20.6-0.8-0.8-0.7-0.5-0.50.4-0.4-0.4-0.3-0.3-0.4-0.4-0.3-0.3-0.4-0.4-0.2
Breakpoint value in progressive ratio session0.30.41.0-1.0-1.0-1.0-0.9-0.40.7-0.7-0.5-0.4-0.4-0.4-0.5-0.1-0.3-0.6-0.8-0.3
Number of licking bursts0.00.10.2-0.3-0.0-0.2-0.1-0.30.10.1-0.0-0.10.00.10.10.00.50.40.50.1
Context. condit. distance diff. score0.20.30.4-0.5-0.6-0.5-0.5-0.40.4-0.5-0.3-0.3-0.6-0.6-0.6-0.6-0.5-0.6-0.5-0.5
Locomotion velocity, session 10.91.01.60.80.70.91.01.0-1.11.01.31.00.91.00.90.81.11.11.01.0
Locomotion distance, session 10.30.40.80.50.40.60.70.8-0.80.60.90.90.60.70.60.60.50.50.40.7
Locomotion velocity, session 20.10.10.3-0.5-0.5-0.4-0.3-0.20.2-0.2-0.1-0.0-0.2-0.1-0.2-0.2-0.4-0.4-0.2-0.0
Locomotion distance, session 20.00.00.0-0.0-0.1-0.00.00.0-0.10.00.10.1-0.00.10.0-0.0-0.1-0.1-0.10.1
Locomotion velocity, session 31.01.21.8-1.3-1.3-1.2-1.1-1.01.0-1.1-0.9-0.8-1.1-1.1-1.1-1.1-1.0-1.1-1.1-1.0
Locomotion distance, session 31.11.21.3-1.1-1.1-1.1-1.1-1.11.1-1.1-1.0-1.1-1.1-1.0-1.0-1.1-1.0-1.1-1.1-1.1
Stereotopy head waving bouts, day 32.32.73.31.51.51.61.61.7-1.71.61.81.61.61.61.61.71.61.81.71.6
Stereotopy head waving duration, day 32.12.63.61.21.21.41.61.6-1.71.61.91.71.51.51.51.61.61.81.81.7
Locomotion velocity, session 70.50.50.9-0.3-0.2-0.4-0.6-0.70.7-0.7-0.9-0.8-0.8-0.8-0.8-0.7-0.8-0.7-0.7-1.0
Locomotion distance, session 70.30.30.6-0.2-0.2-0.3-0.5-0.60.6-0.5-0.8-0.6-0.6-0.7-0.6-0.6-0.5-0.6-0.7-0.8
Stereotopy head waving bouts, day 70.00.00.3-0.5-0.5-0.3-0.1-0.1-0.0-0.00.30.0-0.1-0.0-0.1-0.00.10.20.30.1
Stereotopy head waving duration, day 70.10.10.4-0.4-0.3-0.10.10.2-0.30.20.60.40.20.30.20.20.40.50.60.5
Locomotion velocity, session 80.50.61.40.60.40.70.91.0-1.00.81.11.20.70.70.60.60.70.60.60.8
Locomotion distance, session 80.10.10.2-0.2-0.4-0.2-0.1-0.00.0-0.20.00.1-0.4-0.3-0.4-0.4-0.3-0.5-0.3-0.3
Degree of sensitization distance0.70.71.21.01.11.00.90.8-0.80.90.70.80.80.70.70.80.80.80.90.7
Degree of sensitization stereotypy0.10.10.5-0.7-0.7-0.5-0.3-0.30.2-0.30.0-0.2-0.3-0.2-0.3-0.3-0.1-0.2-0.1-0.1
Conditioned locomotion1.72.02.51.31.41.41.41.4-1.41.41.41.31.41.41.41.41.51.61.61.4
Cocaine response after cond. corrected0.20.20.40.40.50.50.50.5-0.50.40.50.40.50.60.50.50.60.50.60.5
Cocaine response after cond. not corrected0.60.61.00.70.70.80.80.9-0.90.81.00.90.70.70.70.70.90.80.90.7
Cocaine response before conditioning0.00.00.2-0.1-0.1-0.00.10.1-0.20.10.30.4-0.1-0.2-0.2-0.1-0.0-0.00.10.0
Saline control response0.40.51.3-1.1-1.1-1.0-0.8-0.80.7-0.6-0.6-0.5-0.7-0.6-0.6-0.6-0.6-0.4-0.5-0.4
Bone: connectivity density0.10.20.40.0-0.00.10.30.4-0.50.40.60.60.40.50.50.40.50.50.40.6
Bone: cortical apparent density0.30.40.8-0.3-0.3-0.4-0.6-0.70.7-0.6-0.8-0.9-0.6-0.6-0.6-0.7-0.8-0.6-0.6-0.8
Bone: cortical area1.21.93.1-1.7-1.7-1.7-1.5-1.41.4-1.4-1.4-1.1-1.1-1.3-1.3-1.1-1.4-1.5-1.4-1.0
Bone: cortical porosity0.40.51.00.60.50.60.70.8-0.80.80.81.00.60.60.60.70.60.60.50.8
Bone: cortical porosity0.40.50.90.60.60.60.70.7-0.70.80.70.90.60.60.60.70.70.60.60.7
Bone: cortical thickness0.20.30.6-0.8-0.8-0.8-0.6-0.50.5-0.5-0.5-0.3-0.3-0.4-0.4-0.3-0.4-0.5-0.4-0.2
Bone: cortical thickness0.20.21.0-1.0-0.9-0.9-0.7-0.40.4-0.3-0.3-0.10.10.00.00.1-0.1-0.1-0.10.4
Bone: cortical tissue density0.30.40.8-0.3-0.3-0.4-0.6-0.70.7-0.6-0.8-0.9-0.6-0.6-0.6-0.7-0.8-0.6-0.6-0.8
Condit. Reinf. active minus inactive responses0.30.40.6-0.4-0.4-0.5-0.6-0.70.7-0.6-0.7-0.8-0.7-0.7-0.7-0.6-0.4-0.3-0.7-0.8
Condit. Reinf. active-inactive response ratio0.10.10.40.40.50.40.30.2-0.20.30.20.00.20.20.20.30.60.60.30.1
Condit. Reinf. active responses1.82.22.7-1.4-1.3-1.4-1.5-1.61.5-1.4-1.6-1.6-1.6-1.6-1.6-1.5-1.4-1.3-1.4-1.6
Condit. Reinf. inactive responses1.51.92.5-1.4-1.4-1.4-1.3-1.31.3-1.3-1.3-1.2-1.4-1.3-1.4-1.4-1.6-1.6-1.3-1.3
Incentive salience index mean1.41.82.4-1.2-1.1-1.3-1.4-1.51.5-1.3-1.5-1.5-1.4-1.4-1.3-1.2-1.0-1.0-1.3-1.4
Condit. Reinf. lever presses2.43.44.3-2.0-1.9-2.0-2.0-2.12.0-1.9-2.0-1.9-1.7-1.7-1.7-1.7-1.6-1.6-1.8-1.7
Condit. Reinf. active minus inactive responses0.00.00.1-0.2-0.4-0.2-0.1-0.0-0.0-0.10.20.0-0.1-0.1-0.1-0.10.1-0.0-0.1-0.0
Condit. Reinf. active-inactive response ratio0.40.50.70.70.60.80.80.8-0.80.60.90.70.50.60.50.50.70.60.60.5
Condit. Reinf. active responses0.50.61.0-1.0-1.0-0.9-0.9-0.80.8-0.8-0.7-0.8-0.8-0.8-0.8-0.8-0.6-0.6-0.8-0.7
Condit. Reinf. inactive responses2.63.34.0-2.0-1.9-2.0-1.9-1.91.9-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.7-1.7-1.8-1.7
Condit. Reinf. lever presses1.62.22.7-1.6-1.6-1.5-1.5-1.51.4-1.5-1.2-1.5-1.6-1.5-1.5-1.6-1.2-1.2-1.3-1.5
Condit. Reinf. lever reinforcers received0.50.81.0-1.0-1.0-0.9-0.9-0.90.8-0.9-0.7-0.8-0.9-0.9-0.9-0.9-0.7-0.7-0.8-0.9
Conditioned reinforcement - actives0.10.10.4-0.6-0.6-0.4-0.2-0.30.1-0.30.1-0.4-0.5-0.4-0.4-0.3-0.3-0.2-0.1-0.3
Conditioned reinforcement - inactives0.40.61.2-1.1-1.1-0.8-0.7-0.80.6-0.8-0.5-0.9-0.9-0.6-0.7-0.8-0.5-0.4-0.4-0.8
Conditioned locomotion0.00.10.2-0.5-0.5-0.4-0.20.1-0.0-0.00.20.10.00.00.10.50.10.0-0.00.3
Patch foraging indifference point 0 sec0.20.31.6-1.3-1.0-1.1-0.8-0.60.5-0.4-0.4-0.3-0.1-0.1-0.1-0.00.00.00.10.2
Patch foraging indifference point AUC0.00.00.10.30.40.20.1-0.20.1-0.0-0.2-0.1-0.1-0.1-0.1-0.3-0.00.1-0.1-0.3
Delay disc. indifference point, 0s delay0.00.00.1-0.4-0.4-0.3-0.2-0.20.1-0.2-0.1-0.1-0.2-0.1-0.2-0.2-0.3-0.1-0.0-0.1
Delay disc. indifference point, 16s delay1.31.52.4-1.5-1.6-1.4-1.3-1.01.1-1.3-0.8-1.1-1.2-1.1-1.1-0.9-1.4-1.3-1.0-1.1
Delay disc. indifference point, 2s delay0.00.00.1-0.1-0.20.00.10.1-0.2-0.00.20.0-0.1-0.1-0.2-0.2-0.2-0.2-0.1-0.0
Delay disc. indifference point, 24s delay2.32.63.7-1.7-1.9-1.5-1.5-1.21.3-1.7-1.0-1.5-1.9-1.7-1.8-1.5-1.9-1.8-1.5-1.9
Delay disc. indifference point, 4s delay1.51.62.2-1.0-1.1-1.0-1.1-1.11.1-1.3-1.0-1.3-1.4-1.4-1.4-1.4-1.4-1.4-1.3-1.5
Delay disc. indifference point, 8s delay0.00.00.20.0-0.10.10.20.3-0.30.00.50.2-0.10.10.00.1-0.00.10.1-0.0
Indifference point function ln k0.51.01.80.70.50.81.01.2-1.21.01.41.20.90.90.91.00.90.80.91.1
Indifference point function log k0.51.01.80.70.50.81.01.2-1.21.01.41.20.90.90.91.00.90.80.91.1
Patch foraging total patch changes 0 sec0.20.31.6-1.3-1.1-1.1-0.8-0.60.5-0.4-0.4-0.3-0.2-0.2-0.2-0.1-0.0-0.1-0.00.1
Patch foraging total patch changes 12 sec1.21.62.8-1.7-1.4-1.5-1.4-1.51.3-1.2-1.3-1.2-1.1-1.2-1.1-1.2-0.8-0.8-0.9-1.0
Patch foraging total patch changes 18 sec0.71.11.4-1.2-1.1-1.1-1.1-1.11.1-1.1-1.0-1.1-1.1-1.0-1.0-1.0-1.0-0.8-0.8-1.1
Patch foraging total patch changes 24 sec1.01.82.8-1.7-1.5-1.6-1.5-1.51.4-1.4-1.4-1.5-1.2-1.2-1.2-1.2-1.0-1.0-1.0-1.2
Patch foraging total patch changes 6 sec1.42.13.4-1.8-1.6-1.7-1.6-1.71.5-1.4-1.6-1.3-1.4-1.4-1.4-1.5-1.1-1.0-1.0-1.3
Patch foraging time to switch 0 sec0.20.51.0-0.3-0.3-0.3-0.5-0.40.6-0.7-0.6-0.8-0.8-0.9-0.8-0.5-0.9-0.8-0.7-1.0
Patch foraging water rate 0 sec0.40.81.90.20.20.40.60.7-0.90.90.91.21.11.11.10.81.10.90.81.4
Patch foraging water rate 12 sec0.00.10.3-0.0-0.00.10.20.1-0.30.30.40.30.20.20.2-0.10.50.30.40.4
Patch foraging water rate 18 sec0.10.10.5-0.1-0.10.00.20.1-0.30.40.30.30.40.50.50.30.70.50.40.7
Patch foraging water rate 24 sec0.30.50.80.50.40.60.70.6-0.80.70.70.70.70.70.80.50.90.70.60.9
Patch foraging water rate 6 sec0.10.10.4-0.2-0.2-0.10.10.0-0.20.20.20.30.40.50.50.20.50.30.30.6
Seeking ratio, delayed vs. immediate footshock0.50.61.0-0.8-0.7-0.8-0.8-0.90.8-0.7-1.0-0.8-0.6-0.6-0.6-0.8-0.7-0.8-0.9-0.6
Distance traveled before self-admin0.50.61.70.20.30.20.40.4-0.60.80.60.81.01.21.20.91.10.90.61.3
Distance traveled after self-admin0.40.51.10.10.30.30.40.3-0.50.60.50.40.80.70.80.81.10.91.00.9
Extensor digitorum longus weight0.41.42.6-1.1-0.9-1.2-1.3-1.41.4-1.2-1.6-1.5-1.0-1.0-1.0-0.9-0.9-1.0-1.1-1.1
Bone: elastic displacement2.12.53.01.51.51.61.71.7-1.71.61.71.71.51.51.41.51.51.51.61.5
Bone: elastic work1.11.41.71.11.11.21.21.2-1.31.21.31.21.11.01.11.11.31.21.31.1
Bone: endosteal estimation0.00.10.2-0.3-0.3-0.4-0.4-0.30.4-0.3-0.4-0.3-0.2-0.3-0.3-0.2-0.2-0.3-0.3-0.2
Bone: endosteal perimeter1.02.22.8-1.4-1.4-1.4-1.4-1.41.4-1.5-1.4-1.4-1.5-1.7-1.7-1.5-1.5-1.5-1.4-1.5
Epididymis fat weight0.00.10.2-0.4-0.3-0.20.00.1-0.20.10.30.40.00.00.10.20.10.10.40.2
Delta time in closed arm before/after self-admin0.30.30.50.60.60.60.50.6-0.50.50.40.70.50.60.50.50.20.10.40.3
Delta time in open arm before/after self-admin4.94.96.0-2.4-2.4-2.4-2.3-2.12.2-2.3-1.9-2.1-2.2-2.2-2.3-2.2-2.1-2.1-2.1-2.1
Diff in mean of infusions in LGA sessions0.00.10.3-0.4-0.5-0.4-0.30.00.1-0.10.20.1-0.10.0-0.00.0-0.1-0.1-0.30.1
Delay discount exponential model param1.11.21.81.11.31.00.90.7-0.81.10.61.01.31.21.21.11.31.21.11.3
Extinction: sum of active levers before priming1.92.13.8-1.9-2.0-2.0-1.8-1.31.6-1.5-1.3-1.2-1.2-1.1-1.1-0.9-1.2-1.4-1.5-1.0
Active lever presses in extinction session 60.60.61.5-1.1-1.2-1.0-0.9-0.50.7-0.9-0.4-0.6-0.7-0.7-0.8-0.3-0.7-0.9-1.0-0.6
Bone: final force0.00.10.2-0.4-0.4-0.4-0.3-0.30.2-0.2-0.3-0.1-0.1-0.1-0.1-0.2-0.2-0.3-0.2-0.1
Bone: final moment0.20.30.6-0.8-0.8-0.7-0.6-0.60.6-0.5-0.7-0.5-0.5-0.4-0.4-0.5-0.5-0.6-0.5-0.4
Food consumed during 24 hour testing period0.00.00.1-0.1-0.1-0.00.10.1-0.20.10.20.20.20.20.20.20.30.20.20.3
Glucose0.91.41.81.31.31.31.21.1-1.11.21.11.01.21.21.21.11.21.21.21.1
Heart weight1.93.04.1-2.0-1.9-1.9-1.8-1.91.7-1.7-1.8-1.7-1.6-1.6-1.6-1.9-1.7-1.6-1.3-1.6
Delay discount hyperbolic model param1.21.31.91.21.41.00.90.8-0.81.20.61.11.31.31.31.21.41.31.11.3
Intermittent access intake day 1-15 change1.02.13.41.91.81.81.71.6-1.51.51.61.41.21.21.31.21.31.31.31.1
Intermittent access intake escalation1.42.94.12.01.92.01.91.8-1.81.71.91.61.51.51.61.51.61.51.51.4
Intermittent access intake escalation 21.51.72.61.31.21.41.41.4-1.41.31.61.31.21.31.31.21.21.11.11.2
Intermitt. access day 1 inactive lever presses0.00.10.2-0.3-0.3-0.2-0.2-0.20.3-0.4-0.3-0.4-0.5-0.4-0.5-0.1-0.3-0.2-0.2-0.5
Intermitt. access day 15 inactive lever presses1.73.44.1-1.9-1.8-1.9-1.9-1.91.9-1.9-1.8-1.9-2.0-1.9-2.0-1.8-1.5-1.5-1.4-2.0
Intermitt. access escalation Index0.81.12.6-0.6-0.8-0.6-0.7-0.90.8-1.0-0.9-0.9-1.2-1.2-1.2-1.6-1.2-1.1-1.1-1.4
Intermittent access day 1 total infusions0.81.32.3-1.5-1.5-1.3-1.2-1.41.0-1.1-1.1-1.3-1.1-1.0-1.1-1.3-0.8-0.8-0.7-0.9
Intermittent access day 15 total infusions0.81.21.71.01.01.21.21.0-1.31.11.30.90.91.01.00.81.21.21.21.0
Intermittent access terminal intake (last 3 days)0.30.40.80.70.60.80.80.6-0.80.70.90.50.50.50.50.30.70.80.70.5
Intermittent access total infusions0.20.20.40.20.20.40.50.3-0.60.50.60.30.30.40.40.20.60.60.60.5
Intermittent access day 1 locomotion0.50.71.2-1.1-1.0-1.1-0.9-1.10.8-0.8-1.0-0.7-0.6-0.6-0.6-0.9-0.6-0.7-0.7-0.4
Intermittent access day 15 total locomotion0.20.30.60.30.20.30.40.7-0.60.50.60.70.60.50.60.70.40.30.40.8
Intermittent access total locomotion0.00.00.2-0.4-0.4-0.3-0.2-0.10.1-0.10.00.0-0.1-0.1-0.00.0-0.0-0.1-0.10.1
Intermittent access standard deviation0.00.00.20.10.10.10.20.3-0.20.00.40.30.00.10.20.20.20.10.1-0.0
Left kidney weight1.15.07.5-2.7-2.7-2.5-2.3-2.32.1-2.2-2.2-2.0-2.1-2.1-2.1-2.2-2.1-2.2-2.1-1.9
Right kidney weight0.94.05.8-2.4-2.3-2.2-2.1-2.31.9-1.9-2.0-2.1-2.0-2.1-2.0-2.0-1.7-1.7-1.6-1.8
Cocaine induced anxiety2.23.14.8-1.5-1.8-1.6-1.6-1.11.6-1.9-1.3-1.2-2.0-1.9-2.0-1.5-2.1-2.2-2.2-2.1
Post-drug Anxiety0.40.41.0-0.5-0.6-0.5-0.50.00.5-0.7-0.2-0.3-0.9-0.8-0.9-0.2-0.8-0.8-0.8-1.0
Baseline Anxiety6.87.910.72.72.92.82.82.4-2.83.02.72.62.82.72.82.53.13.33.32.8
Tail length4.417.322.0-4.7-4.6-4.5-4.3-4.34.1-4.2-3.9-3.9-4.2-4.2-4.2-4.2-3.9-3.8-3.7-3.9
Length with tail5.222.527.3-5.2-5.2-5.1-4.9-4.84.6-4.8-4.5-4.5-4.7-4.7-4.6-4.8-4.7-4.6-4.4-4.4
Length without tail1.54.95.9-2.2-2.3-2.2-2.2-2.32.1-2.2-2.1-2.3-2.3-2.2-2.2-2.4-2.3-2.2-2.1-2.2
Times rat made contact with spout0.00.00.2-0.10.00.10.1-0.0-0.20.20.30.10.00.00.10.00.40.40.40.1
Lifetime Intake0.10.10.3-0.0-0.00.20.30.2-0.40.30.40.20.30.40.30.10.40.50.50.5
Liver weight, left0.30.60.9-1.0-0.9-0.9-0.9-0.70.8-0.8-0.8-0.7-0.6-0.6-0.6-0.4-0.6-0.9-0.7-0.5
Liver weight, right0.71.31.90.80.90.91.01.0-1.11.21.01.41.21.11.21.01.31.21.21.3
Locomotor activity1.11.72.61.21.41.31.31.1-1.21.31.21.21.21.11.21.31.61.61.51.2
Locomotor testing distance0.61.01.61.01.01.01.00.9-1.01.01.00.91.00.90.91.01.31.31.10.9
Locomotor testing rearing0.10.20.40.1-0.00.20.30.5-0.40.30.50.50.60.50.60.60.50.40.10.6
Locomotion in novel chamber0.10.20.80.50.20.40.50.5-0.50.40.50.90.40.50.40.0-0.00.0-0.10.4
Locomotion in novel chamber post-restriction0.10.10.30.20.10.00.10.3-0.20.30.30.60.40.30.40.50.20.20.00.6
Fecal boli incidents, locomotor time 10.20.30.70.80.80.70.60.6-0.50.60.50.30.50.40.40.70.50.40.70.4
Change in fecal boli incidents, locomotor task0.20.20.40.10.00.30.40.4-0.60.30.50.60.40.30.30.20.40.40.50.5
Time >=10cm from walls, locomotor time 11.51.62.41.11.11.01.01.2-1.11.11.11.41.41.51.61.41.31.31.11.4
Bouts of movement, locomotor time 10.70.80.90.90.91.00.91.0-0.90.91.00.80.90.80.80.90.90.90.80.9
Total resting periods, locomotor time 10.50.50.70.80.80.80.80.8-0.80.70.70.60.70.70.60.70.60.70.80.6
Rest time, locomotor task time 11.41.72.21.41.41.51.51.4-1.41.41.41.41.11.21.21.21.21.21.51.1
Distance moved, locomotor task time 10.60.91.5-0.9-0.9-1.0-1.0-1.11.1-1.0-1.0-1.0-0.8-0.8-0.8-0.8-0.7-0.7-1.2-0.8
Vertical activity count, locomotor time 10.00.00.1-0.2-0.1-0.3-0.3-0.30.3-0.1-0.3-0.20.2-0.10.10.00.20.3-0.30.2
Time >=10cm from walls, locomotor time 20.20.20.5-0.3-0.3-0.5-0.6-0.60.7-0.6-0.7-0.5-0.4-0.2-0.2-0.4-0.4-0.4-0.7-0.6
Bouts of movement, locomotor time 20.30.40.90.90.80.90.80.8-0.80.70.80.90.50.50.50.30.50.60.30.4
Total resting periods, locomotor time 20.20.30.70.80.70.80.70.7-0.70.60.70.80.40.30.40.30.40.50.20.3
Rest time, locomotor task time 22.12.64.22.12.02.01.81.7-1.61.61.61.61.41.41.31.41.41.41.61.2
Distance moved, locomotor task time 21.21.42.2-1.4-1.3-1.5-1.4-1.41.4-1.1-1.3-1.3-0.8-1.1-0.9-0.8-0.8-0.7-1.5-0.7
Vertical activity count, locomotor time 20.10.20.7-0.6-0.5-0.7-0.6-0.50.5-0.3-0.4-0.40.0-0.2-0.1-0.00.10.1-0.90.1
Light reinforcement 10.71.62.31.21.01.21.31.4-1.41.31.41.51.41.31.31.21.01.10.91.5
Light reinforcement 21.21.92.41.31.21.41.41.5-1.51.41.61.41.31.31.31.41.21.31.21.4
Bone: marrow area0.00.00.1-0.2-0.2-0.2-0.2-0.20.2-0.2-0.3-0.2-0.1-0.2-0.2-0.1-0.1-0.2-0.1-0.1
Bone: maximum diameter0.61.12.2-1.3-1.5-1.3-1.2-0.91.0-1.1-1.0-0.8-0.8-0.9-0.9-0.7-1.0-1.1-1.2-0.6
Bone: maximum force0.00.00.1-0.2-0.2-0.2-0.1-0.0-0.10.1-0.00.20.20.20.20.20.10.00.20.3
Bone: maximum moment0.10.10.4-0.6-0.6-0.5-0.4-0.40.3-0.3-0.4-0.2-0.2-0.1-0.1-0.2-0.2-0.3-0.2-0.1
Mean time between licks in bursts0.10.10.50.70.60.60.40.1-0.10.00.1-0.2-0.3-0.3-0.4-0.4-0.2-0.1-0.2-0.6
Mean num. licks in bursts0.00.00.20.1-0.10.10.00.00.0-0.2-0.0-0.1-0.2-0.3-0.2-0.2-0.4-0.3-0.4-0.3
Cd content in liver10.511.616.3-3.9-4.0-3.9-3.6-3.43.4-3.5-3.2-3.0-3.2-3.2-3.2-3.3-3.3-3.3-3.4-2.9
Co content in liver1.51.82.41.11.11.21.31.3-1.41.31.61.41.31.31.31.21.41.41.51.4
Cu content in liver2.63.15.32.32.32.22.01.9-1.81.81.61.71.51.51.51.61.41.51.51.3
Fe content in liver0.10.20.70.80.80.70.50.4-0.30.30.2-0.00.20.20.20.30.30.20.2-0.1
K content in liver0.10.10.20.50.50.50.30.2-0.20.20.20.1-0.0-0.0-0.0-0.00.10.10.2-0.2
Mg content in liver0.10.10.2-0.2-0.4-0.1-0.00.1-0.1-0.20.20.1-0.3-0.4-0.4-0.3-0.4-0.4-0.3-0.3
Mn content in liver1.01.11.5-1.1-1.2-1.0-1.0-0.90.9-1.1-0.8-0.9-1.2-1.2-1.2-1.1-1.1-1.0-1.1-1.1
Na content in liver0.30.31.21.01.10.90.60.4-0.40.60.20.20.40.40.40.30.40.40.60.2
Rb content in liver0.10.10.40.40.60.40.2-0.10.00.1-0.2-0.2-0.2-0.3-0.3-0.2-0.2-0.00.1-0.4
Se content in liver0.20.20.4-0.00.00.10.30.4-0.40.40.60.50.40.40.40.50.50.60.50.5
Sr content in liver3.53.04.0-1.6-1.5-1.7-1.8-1.91.9-1.7-2.0-1.9-1.7-1.7-1.7-1.8-1.6-1.7-1.5-1.8
Zn content in liver0.20.21.3-1.0-1.1-0.8-0.4-0.10.1-0.30.20.2-0.1-0.2-0.2-0.2-0.3-0.2-0.10.2
Bone: minimum diameter2.95.46.2-2.4-2.4-2.5-2.4-2.42.4-2.4-2.5-2.2-2.2-2.2-2.2-2.1-2.3-2.4-2.3-2.1
Time in familiar zone, hab. session 10.20.20.6-0.2-0.2-0.2-0.3-0.50.4-0.4-0.4-0.7-0.6-0.6-0.6-0.6-0.4-0.3-0.4-0.8
Time in novel zone, hab. session 10.40.40.9-0.8-0.9-0.8-0.7-0.50.6-0.6-0.6-0.4-0.5-0.5-0.5-0.5-0.8-0.8-0.8-0.3
Total zone transitions, hab. session 10.40.51.3-1.0-1.1-0.9-0.8-0.60.6-0.7-0.5-0.5-0.7-0.6-0.7-0.7-0.8-0.7-0.7-0.5
Total locomotion distance, hab. session 10.10.10.30.30.10.30.40.5-0.50.30.50.50.20.20.20.2-0.00.00.10.3
Locomotion velocity, hab. session 10.20.30.60.50.30.50.60.7-0.60.50.70.70.40.40.40.40.20.20.30.5
Time in familiar zone, hab. session 20.20.20.50.70.60.60.50.5-0.40.40.40.40.30.30.30.30.40.30.30.2
Time in novel zone, hab. session 21.91.92.8-1.6-1.7-1.6-1.5-1.41.4-1.5-1.3-1.4-1.2-1.3-1.3-1.3-1.4-1.3-1.4-1.2
Total zone transitions, hab. session 20.50.70.9-0.9-1.0-0.8-0.7-0.70.7-0.8-0.6-0.6-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8
Total locomotion distance, hab. session 20.20.20.6-0.2-0.4-0.3-0.3-0.30.3-0.3-0.3-0.2-0.5-0.5-0.6-0.6-0.8-0.7-0.6-0.5
Locomotion velocity, hab. session 20.10.10.3-0.1-0.2-0.1-0.1-0.10.1-0.1-0.10.0-0.3-0.3-0.3-0.3-0.5-0.4-0.3-0.2
Novel to familiar place preference ratio0.10.10.3-0.5-0.4-0.4-0.3-0.20.2-0.2-0.1-0.10.20.10.10.10.10.20.10.3
Novelty place preference0.10.10.5-0.7-0.6-0.6-0.4-0.30.3-0.3-0.1-0.20.10.00.10.1-0.00.1-0.00.2
Time in novel zone, NPP test0.10.10.6-0.8-0.7-0.6-0.5-0.40.3-0.4-0.2-0.3-0.1-0.2-0.2-0.2-0.2-0.0-0.10.0
Total zone transitions, NPP test0.40.61.4-1.2-1.1-1.0-0.8-0.80.6-0.6-0.6-0.5-0.7-0.7-0.7-0.7-0.7-0.6-0.4-0.4
Total locomotion distance, NPP test0.20.20.4-0.6-0.6-0.5-0.4-0.50.4-0.4-0.3-0.3-0.6-0.6-0.6-0.6-0.6-0.5-0.4-0.4
Locomotion velocity, NPP test0.10.10.2-0.5-0.5-0.5-0.4-0.40.3-0.3-0.3-0.2-0.3-0.3-0.3-0.4-0.4-0.4-0.3-0.2
Intraocular pressure1.82.63.21.61.51.51.61.7-1.61.61.51.61.71.81.81.81.51.51.51.7
Delta distance traveled before/after self-admin0.50.51.3-0.7-0.6-0.5-0.6-0.70.7-0.8-0.6-1.1-0.8-1.0-0.9-0.6-0.5-0.4-0.1-0.9
Delta ambulatory time before/after self-admin0.10.10.4-0.2-0.1-0.1-0.1-0.10.2-0.4-0.1-0.6-0.4-0.6-0.6-0.2-0.2-0.20.1-0.6
Parametrial fat weight0.10.10.5-0.3-0.1-0.4-0.4-0.70.5-0.3-0.6-0.4-0.2-0.2-0.2-0.5-0.1-0.1-0.4-0.3
Pavlov. Cond. lever latency3.54.46.12.52.52.42.32.1-2.22.12.02.01.91.91.91.91.92.02.11.7
Pavlov. Cond. magazine entry latency5.67.27.7-2.6-2.6-2.7-2.7-2.72.8-2.7-2.8-2.7-2.6-2.6-2.6-2.6-2.7-2.7-2.7-2.6
Pavlov. Cond. change in total contacts5.45.77.5-2.6-2.7-2.6-2.5-2.32.3-2.5-2.1-2.3-2.4-2.3-2.4-2.4-2.2-2.2-2.3-2.3
Pavlov. Cond. index score4.45.56.6-2.5-2.6-2.6-2.5-2.42.5-2.4-2.4-2.3-2.2-2.2-2.2-2.2-2.3-2.3-2.4-2.1
Pavlov. Cond. latency score4.76.07.1-2.6-2.7-2.7-2.6-2.52.5-2.5-2.5-2.4-2.3-2.3-2.3-2.3-2.3-2.4-2.4-2.2
Pavlov. Cond. lever contacts2.02.43.5-1.8-1.9-1.8-1.7-1.61.6-1.6-1.5-1.5-1.4-1.4-1.4-1.4-1.4-1.5-1.6-1.2
Pavlov. Cond. magazine entry number5.36.67.22.62.62.62.72.6-2.72.72.62.62.52.42.52.52.62.62.72.5
Pavlov. Cond. intertrial magazine entries0.81.01.21.01.01.11.11.1-1.11.01.11.10.90.90.91.00.81.01.10.9
Pavlov. Cond. lever-magazine prob. diff.4.15.16.2-2.5-2.5-2.5-2.4-2.22.3-2.3-2.3-2.2-2.1-2.1-2.1-2.1-2.2-2.3-2.3-2.0
Pavlov. Cond. response bias4.55.66.6-2.5-2.6-2.5-2.5-2.32.4-2.5-2.4-2.3-2.2-2.2-2.2-2.2-2.4-2.4-2.5-2.1
Pavlov. Cond. lever latency1.41.93.21.81.71.61.51.5-1.31.41.21.31.41.31.31.41.31.11.01.2
Pavlov. Cond. magazine entry latency0.70.81.2-0.9-0.9-0.9-0.8-0.90.8-0.8-0.8-0.8-1.0-1.0-1.0-1.1-1.0-1.0-0.8-1.0
Pavlov. Cond. change in total contacts0.20.30.5-0.7-0.6-0.6-0.5-0.60.5-0.5-0.3-0.5-0.7-0.6-0.6-0.7-0.3-0.2-0.2-0.6
Pavlov. Cond. index score1.52.12.7-1.6-1.6-1.5-1.4-1.51.4-1.4-1.2-1.4-1.5-1.4-1.5-1.6-1.3-1.3-1.1-1.4
Pavlov. Cond. latency score1.82.42.9-1.7-1.7-1.6-1.5-1.61.4-1.5-1.3-1.5-1.7-1.6-1.6-1.7-1.5-1.4-1.3-1.6
Pavlov. Cond. lever contacts1.01.42.3-1.5-1.5-1.4-1.2-1.31.1-1.1-0.9-1.0-1.2-1.1-1.1-1.3-1.1-1.0-0.9-1.1
Pavlov. Cond. magazine entry number0.60.71.01.00.90.90.81.0-0.80.80.70.91.00.91.01.00.70.70.60.9
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.2-0.2-0.3-0.3-0.20.3-0.2-0.4-0.2-0.2-0.2-0.1-0.2-0.4-0.3-0.4-0.1
Pavlov. Cond. lever-magazine prob. diff.1.21.52.0-1.4-1.4-1.3-1.2-1.41.2-1.2-1.1-1.2-1.3-1.2-1.3-1.4-1.1-1.1-0.9-1.2
Pavlov. Cond. response bias0.81.11.7-1.3-1.2-1.2-1.1-1.21.0-1.0-0.9-1.0-1.2-1.0-1.1-1.2-1.0-0.9-0.8-1.1
Time in closed arm before self-admin0.10.10.20.20.20.20.20.3-0.20.30.30.20.40.20.20.30.40.40.20.4
Time in closed arm after self-admin2.22.43.11.71.81.61.61.5-1.51.61.41.61.61.51.51.41.51.51.51.5
Time in open arm before self-admin0.10.10.1-0.3-0.3-0.4-0.4-0.40.4-0.3-0.3-0.3-0.4-0.3-0.2-0.2-0.3-0.3-0.4-0.4
Time in open arm after self-admin3.84.25.6-2.4-2.4-2.3-2.1-2.12.0-2.1-1.9-1.9-2.1-1.9-2.0-2.0-1.9-1.9-1.8-1.9
Bone: periosteal estimation0.61.32.0-1.4-1.4-1.4-1.3-1.21.2-1.2-1.3-1.0-0.9-1.1-1.1-0.9-1.1-1.2-1.1-0.8
Bone: periosteal perimeter1.01.72.3-1.5-1.5-1.4-1.3-1.21.2-1.3-1.2-1.0-1.3-1.4-1.4-1.3-1.3-1.4-1.3-1.2
Bone: post-yield work0.00.00.00.00.00.00.10.1-0.10.10.10.10.10.10.10.10.10.10.20.1
Progressive ratio test 1 active lever presses1.51.92.5-1.5-1.4-1.3-1.3-1.51.3-1.4-1.4-1.6-1.4-1.4-1.3-1.5-1.2-1.1-1.1-1.4
Progressive ratio test 1 breakpoint1.31.62.2-1.4-1.3-1.2-1.2-1.51.2-1.3-1.3-1.5-1.3-1.3-1.2-1.4-1.1-1.0-1.0-1.3
Progressive ratio test 1 inactive lever presses2.43.54.1-2.0-1.9-2.0-2.0-2.02.0-1.9-1.9-1.9-1.9-1.7-1.8-1.7-1.8-1.7-1.7-1.9
Progressive ratio test 2 active lever presses0.20.30.5-0.6-0.7-0.5-0.5-0.50.4-0.5-0.3-0.7-0.5-0.5-0.5-0.5-0.6-0.5-0.4-0.5
Progressive ratio test 2 breakpoint0.20.20.4-0.5-0.6-0.4-0.3-0.40.3-0.4-0.2-0.6-0.4-0.4-0.4-0.4-0.5-0.4-0.3-0.4
Progressive ratio test 2 inactive lever presses0.61.01.9-1.3-1.4-1.2-1.1-0.90.9-1.0-0.7-1.1-1.0-0.8-0.9-0.7-1.0-0.9-0.8-0.9
Incentive Sensitization - Responses0.00.00.10.0-0.20.10.1-0.0-0.2-0.00.2-0.1-0.2-0.1-0.1-0.3-0.4-0.3-0.2-0.2
Incentive Sensitization - Breakpoint0.00.00.2-0.0-0.20.00.1-0.0-0.1-0.10.2-0.2-0.2-0.2-0.2-0.3-0.4-0.3-0.3-0.2
Sum of active levers in priming session hrs 5-61.61.52.6-1.6-1.6-1.6-1.4-1.11.3-1.3-1.0-1.2-1.1-1.1-1.0-0.8-1.1-1.1-1.2-1.0
Progressive ratio0.91.43.50.10.10.30.70.9-1.11.11.31.61.41.41.41.31.41.41.21.9
Food seeking constrained by brief footshock0.10.10.20.20.20.1-0.0-0.20.1-0.2-0.3-0.2-0.3-0.3-0.4-0.4-0.2-0.2-0.3-0.4
Seeking ratio, punishment vs. effort0.71.12.90.10.1-0.1-0.5-0.80.9-0.9-1.1-1.3-1.3-1.3-1.3-1.2-1.1-1.1-1.0-1.7
Retroperitoneal fat weight0.52.23.2-1.8-1.8-1.7-1.5-1.41.4-1.4-1.2-1.1-1.5-1.5-1.5-1.5-1.4-1.4-1.5-1.4
Reaction time number correct0.71.43.3-1.8-1.7-1.7-1.4-1.51.2-1.1-1.2-1.2-0.9-0.8-0.8-1.1-0.9-0.8-0.6-0.6
Reaction time mean minus median2.15.16.52.52.52.52.32.2-2.22.22.12.02.42.22.32.12.12.22.22.2
Reaction time mean minus median AUC1.43.64.82.22.22.12.01.9-1.81.81.81.62.01.81.81.71.81.81.81.8
Reaction time num false alarms2.12.94.42.12.02.02.01.8-1.91.91.82.11.31.61.51.31.31.41.61.2
Reaction time num false alarms AUC2.33.64.82.22.22.12.11.9-2.02.11.92.21.61.91.71.51.51.71.81.5
Reaction time trials correct on left0.71.43.3-1.8-1.7-1.7-1.4-1.51.2-1.1-1.2-1.2-0.9-0.8-0.8-1.1-0.9-0.8-0.6-0.6
Reaction time trials on left0.61.22.9-1.7-1.6-1.6-1.3-1.41.1-1.0-1.1-1.1-0.8-0.7-0.7-1.0-0.8-0.7-0.5-0.5
Reaction time mean3.86.19.83.13.03.02.72.7-2.52.52.42.42.32.32.32.21.92.02.12.0
Reaction time mean AUC4.06.49.53.13.03.02.82.8-2.52.52.42.42.42.42.42.42.12.12.32.2
Median of all reaction times2.73.97.12.72.52.52.32.3-2.02.01.92.01.71.71.71.71.41.41.61.4
Reaction time omissions2.33.44.12.01.92.01.91.9-1.91.82.01.71.81.71.71.61.81.91.71.8
Reaction time false alarm rate2.94.06.72.62.52.42.32.2-2.12.12.12.31.61.81.61.61.51.51.61.3
Reaction time premature initiation rate0.10.20.4-0.10.0-0.2-0.4-0.50.5-0.4-0.6-0.5-0.4-0.3-0.4-0.5-0.6-0.4-0.4-0.6
Reaction time premature initiations0.20.40.8-0.7-0.5-0.7-0.7-0.90.7-0.5-0.8-0.7-0.5-0.3-0.4-0.6-0.6-0.4-0.3-0.4
Std. dev. reaction times4.99.111.03.33.33.33.23.2-3.13.03.02.93.02.92.92.82.72.82.92.9
Reaction time trials completed0.61.22.9-1.7-1.6-1.6-1.3-1.41.1-1.0-1.1-1.1-0.8-0.7-0.7-1.0-0.8-0.7-0.5-0.5
Reaction time trials AUC0.81.53.3-1.8-1.7-1.7-1.5-1.51.2-1.1-1.2-1.2-1.0-0.9-0.8-1.1-0.9-0.8-0.6-0.6
Run reversals in cocaine runway, females0.00.00.1-0.2-0.2-0.2-0.2-0.10.2-0.3-0.1-0.3-0.3-0.1-0.10.0-0.1-0.0-0.3-0.3
Run reversals in cocaine runway, males0.30.30.70.90.70.70.60.7-0.50.40.50.50.30.30.30.50.40.20.00.2
Latency to leave start box in cocaine runway0.80.91.41.21.11.11.01.1-0.90.90.70.91.01.11.11.10.70.60.70.9
Latency to leave start box in cocaine runway, F1.92.23.31.71.81.71.51.5-1.41.51.21.21.41.61.61.61.21.21.41.3
Latency to leave start box in cocaine runway, M0.10.00.2-0.1-0.2-0.2-0.2-0.00.1-0.2-0.20.1-0.0-0.0-0.0-0.3-0.4-0.4-0.5-0.1
Std. dev. time between licks in bursts0.50.61.3-0.3-0.5-0.4-0.5-0.60.6-0.8-0.6-0.7-1.0-1.0-1.0-1.0-0.9-0.9-0.9-1.1
Total sessions with >9 infusions0.70.91.8-1.3-1.3-1.2-1.1-1.11.0-0.9-1.0-0.8-0.7-0.7-0.7-0.8-0.7-0.6-0.7-0.6
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.2-0.1-0.10.00.1-0.20.1-0.3-0.3-0.2-0.2-0.0-0.1-0.0-0.1-0.4
Short access day 10 total inactive lever presses0.61.42.2-1.2-1.1-1.3-1.3-1.21.4-1.2-1.5-1.0-1.2-1.1-1.1-0.9-1.1-1.2-1.2-1.2
Short access day 1 total infusions0.20.20.7-0.8-0.8-0.7-0.6-0.40.5-0.5-0.5-0.3-0.3-0.2-0.2-0.2-0.4-0.4-0.4-0.2
Short access day 10 total infusions0.30.40.8-0.9-0.9-0.7-0.6-0.80.5-0.6-0.5-0.6-0.6-0.5-0.5-0.7-0.4-0.3-0.4-0.4
Short access total infusions0.10.20.6-0.8-0.8-0.6-0.5-0.60.3-0.4-0.4-0.3-0.3-0.2-0.2-0.5-0.1-0.1-0.1-0.1
Short access day 1 locomotion1.21.53.4-1.9-1.8-1.8-1.6-1.11.3-1.3-1.1-0.9-1.0-1.0-0.9-0.5-1.0-1.0-1.1-0.7
Short access day 10 total locomotion0.10.10.30.50.50.40.30.3-0.20.40.20.60.30.30.30.30.30.10.00.3
Short access total locomotion0.10.10.3-0.5-0.4-0.5-0.4-0.30.3-0.2-0.30.10.0-0.00.00.10.0-0.0-0.10.2
One hour access (0.3 mA shock)0.91.11.5-0.9-1.1-0.9-0.9-0.90.8-1.0-0.7-1.0-1.2-1.2-1.1-1.2-1.2-1.1-1.1-1.2
Compulsive drug intake3.74.45.3-1.8-1.7-1.9-2.1-2.12.2-2.1-2.3-2.2-2.1-2.3-2.2-2.1-2.2-2.0-2.0-2.3
One hour access (shock baseline)0.71.12.11.00.91.21.21.1-1.31.11.41.10.81.01.00.81.01.01.00.9
Social response proportion0.00.00.10.20.20.10.10.2-0.00.10.00.10.20.30.20.40.20.0-0.10.2
Social responses0.71.01.5-1.0-1.1-1.1-1.1-1.01.1-1.0-1.0-0.9-0.9-0.8-0.9-0.9-0.8-1.0-1.2-0.8
Social time0.00.00.2-0.2-0.3-0.2-0.20.10.1-0.20.00.10.10.10.10.10.0-0.1-0.40.2
Soleus weight3.19.211.52.52.62.72.93.0-3.03.03.03.13.33.23.23.23.03.13.23.4
Bone: stiffness0.20.30.6-0.8-0.7-0.8-0.7-0.60.6-0.5-0.7-0.4-0.2-0.2-0.2-0.2-0.5-0.6-0.4-0.1
Tibialis anterior weight0.93.14.3-1.8-1.6-1.8-1.9-2.02.0-1.8-2.1-2.1-1.6-1.7-1.7-1.6-1.5-1.5-1.6-1.7
Time to tail flick, vehicle, before self-admin0.70.71.61.31.21.31.11.1-0.90.70.90.70.40.40.30.60.50.60.80.2
Time to tail flick, vehicle, after self-admin0.10.20.4-0.6-0.6-0.6-0.6-0.50.5-0.4-0.2-0.3-0.4-0.2-0.2-0.4-0.2-0.3-0.4-0.3
Time to tail flick, test, before self-admin0.50.50.90.60.60.70.80.7-0.80.70.80.60.70.80.70.50.70.70.90.7
Time to tail flick, test, after self-admin0.30.30.60.80.60.70.70.6-0.60.60.60.70.60.60.60.20.40.30.20.6
Delta time to tail flick, vehicle, before/after SA0.50.51.1-1.0-0.9-1.0-0.9-0.80.8-0.6-0.7-0.6-0.4-0.3-0.3-0.5-0.4-0.6-0.7-0.2
Delta time to tail flick, test, before/after SA0.10.10.10.30.20.20.20.2-0.20.30.10.40.30.10.20.10.20.1-0.20.4
Tibia length2.15.87.9-2.6-2.3-2.7-2.6-2.82.6-2.3-2.8-2.4-2.3-2.3-2.3-2.4-2.3-2.2-2.1-2.2
Ambulatory time before self-admin1.21.83.50.81.00.80.90.9-1.11.41.11.41.61.81.71.51.71.51.21.9
Ambulatory time after self-admin1.51.83.11.01.21.11.21.2-1.21.31.41.11.41.31.31.51.81.61.51.5
Bone: tissue strength0.10.10.40.70.60.60.50.3-0.40.30.30.30.10.20.20.00.20.20.2-0.1
Total heroin consumption1.01.12.7-1.5-1.7-1.4-1.2-0.81.0-1.1-0.6-0.7-0.9-0.8-0.9-0.9-0.8-1.1-1.4-0.7
Bone: trabecular number0.20.20.40.20.20.30.40.4-0.50.50.60.60.50.50.50.50.50.60.70.6
Bone: trabecular spacing1.11.52.1-1.0-1.0-1.1-1.1-1.21.2-1.2-1.2-1.1-1.3-1.3-1.3-1.3-1.3-1.4-1.5-1.4
Bone: trabecular thickness0.20.20.7-0.00.10.10.20.2-0.30.40.40.40.50.50.50.50.70.80.80.6
Bone: trabecular tissue density0.40.61.30.20.3-0.1-0.4-0.70.8-0.6-1.0-0.9-0.8-0.8-0.9-0.8-0.9-0.9-0.8-1.1
Water consumed over 24 hours0.10.10.3-0.6-0.5-0.4-0.3-0.40.2-0.2-0.1-0.1-0.4-0.3-0.3-0.40.0-0.1-0.1-0.2
Number of responses in last shaping day0.70.71.90.30.40.40.60.9-0.70.70.90.90.90.80.81.41.21.11.01.0