Hub : Genes

Oxld1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Oxld1 0.06 0.03 3.3e-09 0.09 0.07 0.07 0.08 9.5e-11 3.4e-08 2.6e-08 1.2e-09
2 PL gene expression Oxld1 0.05 0.03 8.9e-06 0.04 0.05 0.05 0.05 1.7e-05 3.4e-06 2.4e-06 2.7e-06
3 Brain mRNA stability Oxld1 0.05 0.03 9.8e-06 0.03 0.05 0.03 0.04 6.3e-04 1.4e-05 7.0e-04 2.7e-04
4 BLA mRNA stability Oxld1 0.12 0.07 4.1e-06 0.05 0.09 0.07 0.08 1.0e-03 2.4e-05 8.7e-05 6.7e-05
5 Adipose intron excision ratio chr10_105729871_105730476 0.03 0.02 7.8e-04 0 0.01 0 0 2.5e-01 5.2e-02 1.1e-01 2.0e-01
6 PL mRNA stability Oxld1 0.1 0.05 5.1e-13 0.09 0.12 0.12 0.12 1.2e-09 1.8e-13 6.9e-13 1.0e-12
7 Liver gene expression Oxld1 0.09 0.06 3.1e-08 0.04 0.06 0.06 0.06 5.7e-05 1.5e-07 1.7e-07 5.1e-07
8 BLA gene expression Oxld1 0.11 0.07 2.9e-05 0.05 0.09 0.08 0.07 9.1e-04 1.0e-05 4.5e-05 8.2e-05
9 NAcc gene expression Oxld1 0.04 0.02 9.4e-05 0.03 0.03 0.03 0.03 1.2e-04 1.2e-04 3.1e-04 1.1e-04
10 OFC gene expression Oxld1 0.17 0.12 5.9e-03 0.07 0.03 0.05 0.06 8.5e-03 5.9e-02 2.3e-02 1.5e-02
11 OFC mRNA stability Oxld1 0.26 0.14 4.2e-04 0.1 0.1 0.08 0.15 2.4e-03 2.8e-03 5.8e-03 2.0e-04
12 Brain alternative TSS XM_039085010.1 0.04 0.03 8.5e-03 0.03 0.01 0.02 0.02 5.7e-04 2.4e-02 4.1e-03 4.0e-03
13 Brain gene expression Oxld1 0.07 0.05 1.6e-04 0.05 0.04 0.04 0.05 3.9e-05 1.2e-04 8.9e-05 2.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.20.40.8-0.7-0.80.40.40.40.30.80.80.8-0.9-0.20.00.8
Area under the delay curve1.71.82.91.71.6-1.5-1.5-1.5-1.4-1.3-1.4-1.11.0-0.81.1-0.8
BMI with tail0.82.45.2-1.8-1.81.21.21.01.12.01.72.3-2.20.2-0.21.6
BMI without tail6.212.822.1-4.1-4.22.93.02.52.74.64.44.7-4.40.3-0.44.3
Body weight3.815.721.8-4.7-4.64.44.44.24.14.44.44.0-3.12.9-2.52.8
Weight adjusted by age2.63.04.6-1.8-1.72.02.01.92.01.91.62.1-1.21.6-1.50.6
Bone surface0.20.40.7-0.8-0.80.80.80.80.70.50.70.2-0.00.4-0.50.4
Bone volume0.30.40.7-0.8-0.90.70.70.70.60.80.80.6-0.60.2-0.30.6
Breakpoint value in progressive ratio session0.60.72.5-0.5-0.40.70.70.81.00.3-0.10.3-0.71.6-1.6-0.7
Number of licking bursts0.20.30.8-0.6-0.60.30.30.30.10.60.80.4-0.4-0.30.30.9
Context. condit. distance diff. score1.51.84.9-1.0-1.20.30.30.10.11.71.52.0-2.2-1.01.02.2
Locomotion velocity, session 13.03.36.22.02.1-1.5-1.4-1.3-1.2-2.4-2.3-2.22.5-0.00.1-2.3
Locomotion distance, session 12.33.04.91.81.7-2.1-2.1-2.2-2.2-1.2-1.3-0.60.6-2.22.20.0
Locomotion velocity, session 24.65.47.32.72.7-2.4-2.4-2.3-2.4-2.7-2.5-2.52.3-1.41.5-1.7
Locomotion distance, session 20.50.72.30.70.6-0.9-0.9-1.0-1.1-0.2-0.20.3-0.3-1.51.40.7
Locomotion velocity, session 31.92.23.51.71.7-1.4-1.4-1.3-1.2-1.8-1.9-1.51.8-0.40.3-1.6
Locomotion distance, session 32.83.14.22.02.0-2.0-2.0-2.0-1.9-1.9-2.0-1.51.3-1.11.2-1.2
Stereotopy head waving bouts, day 30.80.91.81.01.1-0.7-0.7-0.6-0.6-1.2-1.1-1.41.3-0.10.0-1.1
Stereotopy head waving duration, day 30.40.40.80.80.8-0.6-0.6-0.5-0.6-0.8-0.7-0.90.7-0.30.2-0.6
Locomotion velocity, session 70.50.61.00.80.8-1.0-1.0-1.0-1.0-0.6-0.8-0.30.2-0.80.7-0.3
Locomotion distance, session 72.53.26.61.81.6-2.3-2.3-2.4-2.4-0.9-1.2-0.1-0.4-2.62.30.4
Stereotopy head waving bouts, day 70.20.20.3-0.6-0.50.40.40.40.40.60.40.4-0.50.3-0.00.3
Stereotopy head waving duration, day 70.30.40.6-0.8-0.70.80.80.80.70.60.60.1-0.10.6-0.40.3
Locomotion velocity, session 80.70.92.60.60.5-1.0-0.9-1.1-1.10.00.00.3-0.7-1.61.51.0
Locomotion distance, session 82.02.98.3-0.6-0.9-0.3-0.3-0.7-0.71.81.52.5-2.5-2.12.12.9
Degree of sensitization distance1.01.02.9-0.8-0.90.50.60.40.41.21.21.5-1.7-0.50.21.4
Degree of sensitization stereotypy0.50.60.9-0.9-0.90.70.70.60.71.00.80.9-1.00.4-0.10.7
Conditioned locomotion4.45.27.9-2.6-2.72.22.22.02.02.82.82.6-2.60.6-0.72.4
Cocaine response after cond. corrected0.20.20.70.40.4-0.2-0.1-0.10.1-0.5-0.6-0.40.20.5-0.5-0.8
Cocaine response after cond. not corrected0.60.61.10.90.9-0.7-0.7-0.7-0.5-1.0-1.1-1.00.80.1-0.0-1.0
Cocaine response before conditioning0.70.91.50.90.9-1.1-1.1-1.1-1.2-0.7-0.6-0.90.7-1.11.20.1
Saline control response2.93.85.1-2.3-2.32.22.22.12.12.12.21.9-1.31.5-1.31.3
Bone: connectivity density0.20.31.1-0.2-0.2-0.1-0.2-0.3-0.40.40.50.3-0.6-0.90.91.1
Bone: cortical apparent density2.33.04.52.12.1-2.0-2.0-1.9-1.8-1.9-2.1-1.41.3-0.91.0-1.5
Bone: cortical area5.78.612.4-3.4-3.33.53.53.53.52.82.92.1-1.42.9-2.81.2
Bone: cortical porosity1.92.17.1-0.5-0.31.31.31.51.6-0.4-0.3-0.61.12.7-2.5-2.0
Bone: cortical porosity1.71.85.9-0.8-0.61.41.41.61.70.00.0-0.20.52.4-2.3-1.4
Bone: cortical thickness4.67.612.1-3.1-2.93.43.43.53.52.12.31.6-0.93.3-3.20.3
Bone: cortical thickness1.61.92.9-1.5-1.41.61.61.61.71.21.11.1-0.71.7-1.60.2
Bone: cortical tissue density2.63.55.22.32.2-2.1-2.1-2.0-1.9-2.1-2.3-1.61.4-0.91.0-1.6
Condit. Reinf. active minus inactive responses2.22.53.5-1.9-1.91.71.71.61.61.81.81.7-1.51.0-0.81.2
Condit. Reinf. active-inactive response ratio1.11.11.8-1.3-1.31.11.11.01.11.21.11.2-1.30.7-0.50.7
Condit. Reinf. active responses3.94.76.8-2.6-2.62.42.42.22.22.52.62.3-1.81.3-1.01.8
Condit. Reinf. inactive responses0.91.11.7-1.2-1.21.21.21.11.11.21.31.1-0.80.7-0.51.0
Incentive salience index mean1.82.13.2-1.8-1.81.61.51.51.41.71.71.5-1.30.8-0.51.3
Condit. Reinf. lever presses0.20.20.7-0.3-0.3-0.0-0.0-0.1-0.20.50.50.4-0.5-0.60.80.8
Condit. Reinf. active minus inactive responses0.70.91.6-1.0-1.01.11.11.00.91.01.21.0-0.80.4-0.30.9
Condit. Reinf. active-inactive response ratio1.81.93.1-1.5-1.31.71.81.81.71.11.40.9-0.41.5-1.30.4
Condit. Reinf. active responses0.30.41.4-0.5-0.50.40.40.30.30.70.81.0-1.2-0.20.20.8
Condit. Reinf. inactive responses0.50.61.40.70.6-1.0-1.0-1.0-0.9-0.3-0.50.1-0.6-1.21.00.1
Condit. Reinf. lever presses0.50.73.4-0.5-0.60.20.30.10.21.00.81.6-1.8-0.50.41.0
Condit. Reinf. lever reinforcers received0.50.73.0-0.5-0.60.30.30.10.20.90.81.5-1.7-0.40.41.0
Conditioned reinforcement - actives0.30.30.7-0.4-0.30.10.10.0-0.20.60.60.6-0.8-0.20.70.8
Conditioned reinforcement - inactives1.41.62.1-1.1-1.01.41.51.41.41.21.21.4-1.01.4-1.50.4
Conditioned locomotion0.20.20.3-0.3-0.40.50.40.40.20.60.60.5-0.50.50.20.4
Patch foraging indifference point 0 sec0.10.20.7-0.4-0.50.40.40.40.40.50.20.4-0.80.1-0.50.1
Patch foraging indifference point AUC0.00.00.2-0.00.1-0.1-0.1-0.1-0.1-0.00.10.2-0.2-0.40.30.3
Delay disc. indifference point, 0s delay0.00.00.10.30.2-0.2-0.2-0.2-0.2-0.0-0.10.30.0-0.00.3-0.0
Delay disc. indifference point, 16s delay1.91.94.41.41.2-1.7-1.7-1.8-1.8-0.6-0.80.0-0.0-2.02.10.2
Delay disc. indifference point, 2s delay0.40.50.90.90.9-0.6-0.6-0.6-0.5-0.7-0.8-0.60.80.30.3-0.6
Delay disc. indifference point, 24s delay5.15.07.32.72.7-2.3-2.3-2.2-2.1-2.5-2.7-2.51.9-0.91.1-2.0
Delay disc. indifference point, 4s delay0.50.51.01.00.9-0.7-0.7-0.7-0.6-1.0-0.8-0.90.80.00.3-0.5
Delay disc. indifference point, 8s delay1.21.22.01.31.3-1.0-1.0-0.9-0.8-1.3-1.3-1.41.40.00.2-1.1
Indifference point function ln k0.60.81.31.10.9-1.1-1.1-1.1-1.1-0.7-1.0-0.60.1-0.90.8-0.5
Indifference point function log k0.60.81.31.10.9-1.1-1.1-1.1-1.1-0.7-1.0-0.60.1-0.90.8-0.5
Patch foraging total patch changes 0 sec0.10.21.3-0.4-0.50.30.30.30.40.60.30.7-1.10.0-0.30.2
Patch foraging total patch changes 12 sec0.00.00.3-0.10.00.10.20.20.3-0.1-0.1-0.1-0.10.1-0.5-0.3
Patch foraging total patch changes 18 sec0.30.41.60.1-0.1-0.5-0.5-0.6-0.50.30.10.8-1.1-1.30.80.6
Patch foraging total patch changes 24 sec0.70.92.1-0.8-1.10.90.90.80.91.20.91.3-1.40.4-0.50.6
Patch foraging total patch changes 6 sec0.30.51.1-0.7-0.60.90.90.90.90.40.50.3-0.20.9-1.0-0.1
Patch foraging time to switch 0 sec0.50.71.70.80.9-0.8-0.8-0.7-0.7-0.9-0.9-1.11.3-0.20.4-0.7
Patch foraging water rate 0 sec2.43.98.6-2.1-2.11.81.91.61.72.42.22.5-2.90.5-0.71.7
Patch foraging water rate 12 sec0.71.04.8-0.6-0.80.20.20.00.11.21.01.4-2.2-0.80.71.3
Patch foraging water rate 18 sec1.11.54.7-1.2-1.20.70.70.50.51.61.51.6-2.2-0.40.51.7
Patch foraging water rate 24 sec3.14.414.6-1.9-2.21.21.30.91.12.72.33.1-3.8-0.40.32.4
Patch foraging water rate 6 sec0.30.42.1-0.4-0.50.20.20.10.00.80.70.7-1.5-0.40.60.9
Seeking ratio, delayed vs. immediate footshock1.41.62.6-1.6-1.41.41.41.31.31.41.51.4-0.41.0-0.81.1
Distance traveled before self-admin1.31.43.7-1.1-1.11.31.31.41.60.80.50.6-0.51.6-1.9-0.3
Distance traveled after self-admin0.80.92.8-0.9-1.10.60.60.50.61.21.01.4-1.7-0.2-0.41.0
Extensor digitorum longus weight0.41.75.4-0.7-0.9-0.1-0.1-0.3-0.21.51.21.9-2.3-1.31.32.1
Bone: elastic displacement1.31.52.5-1.4-1.31.51.51.51.60.90.90.6-0.71.3-1.5-0.0
Bone: elastic work6.58.414.9-3.1-2.93.53.63.73.81.92.01.4-0.73.6-3.9-0.4
Bone: endosteal estimation0.20.51.5-0.3-0.4-0.2-0.2-0.3-0.30.80.60.8-1.0-0.90.91.2
Bone: endosteal perimeter0.61.31.9-1.4-1.41.31.31.31.31.21.20.8-0.31.0-0.90.7
Epididymis fat weight1.33.05.0-2.1-2.11.51.51.41.32.22.02.2-2.10.6-0.41.8
Delta time in closed arm before/after self-admin0.10.10.60.20.20.0-0.0-0.0-0.4-0.10.3-0.30.5-0.30.80.3
Delta time in open arm before/after self-admin0.20.21.2-0.3-0.3-0.1-0.1-0.20.00.60.10.8-1.1-0.30.20.3
Diff in mean of infusions in LGA sessions0.20.20.40.40.5-0.4-0.5-0.4-0.3-0.4-0.7-0.40.30.1-0.1-0.5
Delay discount exponential model param2.42.64.1-2.0-1.91.81.81.71.61.81.81.6-1.40.8-1.01.1
Extinction: sum of active levers before priming1.11.12.41.11.3-1.2-1.2-1.1-1.0-1.2-1.6-0.90.6-0.50.4-1.2
Active lever presses in extinction session 60.60.62.30.70.8-0.2-0.2-0.10.0-0.6-1.1-0.3-0.11.2-0.8-1.5
Bone: final force5.18.311.4-3.3-3.33.43.43.33.32.92.92.5-1.82.6-2.51.4
Bone: final moment5.99.613.5-3.6-3.53.63.63.63.73.03.02.7-1.92.9-2.91.3
Food consumed during 24 hour testing period0.50.61.2-0.8-0.80.70.70.70.70.90.80.8-1.10.5-0.40.5
Glucose4.26.315.72.62.9-1.8-1.7-1.4-1.1-3.3-3.4-3.02.91.0-0.9-4.0
Heart weight0.40.50.9-0.7-0.90.70.80.70.80.80.71.0-0.70.4-0.60.4
Delay discount hyperbolic model param2.32.43.9-2.0-1.91.71.71.71.61.71.81.5-1.40.7-1.01.1
Intermittent access intake day 1-15 change0.60.61.1-1.0-0.61.01.01.01.00.60.70.5-0.40.6-1.00.2
Intermittent access intake escalation0.60.50.9-0.9-0.60.90.90.80.90.70.80.6-0.60.5-0.70.4
Intermittent access intake escalation 21.81.84.4-1.3-1.01.61.61.71.80.90.80.7-0.42.1-1.6-0.0
Intermitt. access day 1 inactive lever presses1.11.22.1-1.1-0.81.21.31.31.40.90.81.1-0.91.3-1.40.1
Intermitt. access day 15 inactive lever presses1.41.53.1-1.2-1.21.11.11.00.91.51.51.8-1.80.4-0.21.1
Intermitt. access escalation Index1.31.12.2-1.0-1.20.80.80.60.51.41.51.4-1.2-0.50.41.5
Intermittent access day 1 total infusions0.30.40.7-0.8-0.80.60.60.60.60.60.80.5-0.30.2-0.50.6
Intermittent access day 15 total infusions0.70.81.2-1.1-1.00.90.90.90.81.01.11.0-0.60.3-0.60.8
Intermittent access terminal intake (last 3 days)1.21.31.8-1.3-1.31.31.31.31.21.21.31.0-0.80.9-1.00.8
Intermittent access total infusions0.60.71.0-1.0-1.00.80.90.80.80.91.00.7-0.70.3-0.60.8
Intermittent access day 1 locomotion0.50.51.1-0.7-0.80.60.60.60.40.90.91.0-0.70.30.00.8
Intermittent access day 15 total locomotion0.40.50.9-0.7-0.60.90.90.90.80.50.70.2-0.20.9-0.70.2
Intermittent access total locomotion0.50.50.8-0.7-0.80.90.90.80.70.80.90.7-0.60.8-0.50.5
Intermittent access standard deviation0.70.82.30.70.9-0.2-0.2-0.00.1-1.0-1.2-1.10.71.1-1.1-1.5
Left kidney weight0.20.51.8-0.3-0.10.60.50.70.5-0.20.0-0.61.31.1-0.9-0.5
Right kidney weight0.00.11.2-0.00.10.20.10.2-0.0-0.30.0-0.61.10.2-0.1-0.0
Cocaine induced anxiety4.24.911.7-1.5-1.82.62.62.72.91.51.11.7-1.23.1-3.4-0.4
Post-drug Anxiety0.70.82.9-0.0-0.40.80.80.91.10.2-0.10.6-0.71.5-1.7-0.7
Baseline Anxiety6.67.110.62.72.8-3.1-3.1-3.1-3.3-2.5-2.3-2.41.6-2.63.0-0.9
Tail length5.215.825.0-4.7-4.74.34.34.03.84.75.04.2-3.11.9-1.73.8
Length with tail2.38.513.5-3.2-3.23.73.63.63.32.73.02.1-0.93.0-2.61.3
Length without tail0.92.16.00.90.90.20.10.50.2-1.6-1.4-1.92.21.9-1.5-2.5
Times rat made contact with spout1.21.43.8-0.9-0.81.41.41.51.60.30.40.0-0.11.8-1.9-0.9
Lifetime Intake0.20.20.3-0.5-0.50.40.40.40.30.50.60.3-0.20.2-0.40.5
Liver weight, left0.40.62.10.40.5-0.1-0.10.10.2-0.9-0.9-0.81.20.9-0.9-1.5
Liver weight, right1.72.84.7-1.9-1.92.22.12.21.91.51.80.8-0.11.6-1.30.8
Locomotor activity0.50.81.21.11.1-1.0-1.0-1.0-0.9-0.9-1.1-0.60.5-0.40.6-0.8
Locomotor testing distance0.60.91.61.21.1-1.2-1.3-1.3-1.3-0.6-0.9-0.10.0-0.71.2-0.3
Locomotor testing rearing0.30.51.40.70.5-0.7-0.7-0.8-0.8-0.1-0.30.5-1.2-0.81.00.0
Locomotion in novel chamber0.30.31.20.40.3-0.6-0.6-0.7-0.70.0-0.10.3-0.4-1.11.00.2
Locomotion in novel chamber post-restriction1.82.13.5-1.9-1.71.71.81.71.81.31.60.7-0.60.9-1.41.1
Fecal boli incidents, locomotor time 10.50.50.90.60.7-0.9-0.9-0.9-0.9-0.6-0.6-0.60.4-0.60.9-0.1
Change in fecal boli incidents, locomotor task2.52.35.01.71.7-1.2-1.1-1.0-0.8-2.1-2.0-2.21.70.2-0.5-2.1
Time >=10cm from walls, locomotor time 10.80.82.7-1.0-1.10.40.40.20.11.01.20.5-1.1-1.10.71.6
Bouts of movement, locomotor time 11.61.72.41.51.5-1.5-1.5-1.4-1.4-1.5-1.5-1.11.2-0.90.8-1.0
Total resting periods, locomotor time 12.12.33.31.71.7-1.6-1.6-1.5-1.4-1.8-1.8-1.61.6-0.70.6-1.3
Rest time, locomotor task time 10.40.51.20.60.7-0.3-0.3-0.1-0.1-0.8-0.8-1.01.10.5-0.4-1.0
Distance moved, locomotor task time 10.60.71.4-0.8-1.20.70.70.60.61.11.11.2-0.9-0.2-0.01.0
Vertical activity count, locomotor time 11.61.73.7-1.2-1.70.90.90.70.61.71.61.9-1.8-0.40.41.7
Time >=10cm from walls, locomotor time 20.10.10.4-0.1-0.10.10.10.1-0.1-0.10.4-0.60.6-0.10.30.4
Bouts of movement, locomotor time 21.11.21.81.21.2-1.3-1.3-1.3-1.3-1.0-1.0-0.70.6-1.21.2-0.3
Total resting periods, locomotor time 20.80.91.80.90.9-1.1-1.1-1.2-1.2-0.7-0.6-0.30.3-1.31.30.1
Rest time, locomotor task time 20.10.10.50.20.3-0.2-0.2-0.2-0.2-0.4-0.2-0.70.5-0.10.2-0.0
Distance moved, locomotor task time 20.00.00.30.0-0.20.10.10.10.00.20.30.60.2-0.10.10.2
Vertical activity count, locomotor time 20.40.51.2-0.4-0.60.10.1-0.0-0.20.80.81.0-0.7-0.70.91.1
Light reinforcement 11.52.75.0-1.9-2.01.21.10.90.92.22.12.0-2.2-0.30.42.2
Light reinforcement 22.23.04.7-2.1-2.21.81.71.61.42.22.21.8-1.50.8-0.41.9
Bone: marrow area0.20.51.5-0.2-0.4-0.2-0.2-0.3-0.30.80.60.8-1.0-0.90.91.2
Bone: maximum diameter1.42.63.9-2.0-1.92.01.91.91.81.61.71.1-0.51.4-1.30.9
Bone: maximum force5.18.812.3-3.5-3.53.43.43.33.33.13.22.7-1.92.4-2.31.7
Bone: maximum moment5.810.013.8-3.7-3.63.73.73.63.73.23.22.8-2.02.7-2.71.6
Mean time between licks in bursts1.41.92.71.61.5-1.6-1.7-1.6-1.6-1.3-1.4-1.21.1-1.31.3-0.5
Mean num. licks in bursts0.40.51.7-0.1-0.00.50.60.60.8-0.2-0.3-0.1-0.01.2-1.3-1.1
Cd content in liver1.51.72.91.51.5-1.7-1.6-1.7-1.6-1.0-1.3-0.6-0.1-1.31.3-0.4
Co content in liver0.10.10.30.40.2-0.4-0.4-0.4-0.3-0.1-0.30.2-0.6-0.30.2-0.1
Cu content in liver0.70.82.8-0.3-0.20.80.81.01.0-0.3-0.3-0.50.51.5-1.7-1.2
Fe content in liver0.80.91.51.11.0-1.2-1.2-1.2-1.2-0.8-1.0-0.40.5-1.00.9-0.3
K content in liver2.12.13.7-1.8-1.71.51.41.31.21.81.91.4-1.30.3-0.31.8
Mg content in liver1.01.04.0-0.6-0.80.20.1-0.0-0.21.11.20.8-1.3-1.21.12.0
Mn content in liver0.20.20.5-0.6-0.50.70.70.70.60.30.5-0.10.00.4-0.50.2
Na content in liver0.00.00.2-0.1-0.10.10.10.20.1-0.00.0-0.20.40.1-0.1-0.1
Rb content in liver1.11.43.1-1.2-1.30.90.90.70.71.51.51.3-1.8-0.20.11.7
Se content in liver0.30.41.0-0.7-0.70.60.60.50.50.70.70.5-1.00.3-0.20.6
Sr content in liver1.11.03.50.50.7-0.0-0.00.20.3-1.1-1.1-1.11.41.2-1.2-1.9
Zn content in liver0.20.31.50.20.30.10.10.2-0.1-0.6-0.1-1.11.20.1-0.2-0.3
Bone: minimum diameter3.05.78.0-2.8-2.72.82.82.82.82.32.21.7-1.42.4-2.30.9
Time in familiar zone, hab. session 10.10.10.40.30.3-0.1-0.1-0.10.1-0.4-0.4-0.2-0.10.4-0.4-0.6
Time in novel zone, hab. session 10.10.10.2-0.2-0.10.00.0-0.0-0.10.30.30.2-0.1-0.40.40.5
Total zone transitions, hab. session 10.30.40.80.60.6-0.8-0.8-0.9-0.8-0.2-0.40.3-0.3-0.90.80.2
Total locomotion distance, hab. session 10.40.62.4-0.5-0.50.00.0-0.10.01.00.61.5-1.5-0.40.41.0
Locomotion velocity, hab. session 10.40.62.5-0.5-0.60.10.1-0.00.11.00.61.6-1.4-0.50.31.0
Time in familiar zone, hab. session 20.20.20.50.50.3-0.6-0.6-0.7-0.5-0.1-0.40.4-0.4-0.50.50.1
Time in novel zone, hab. session 20.10.10.40.20.3-0.1-0.1-0.1-0.2-0.3-0.1-0.60.5-0.20.3-0.0
Total zone transitions, hab. session 20.91.23.30.20.1-0.8-0.8-1.0-1.00.50.40.9-1.1-1.81.81.6
Total locomotion distance, hab. session 21.31.75.5-0.9-1.10.20.2-0.0-0.11.61.51.8-1.8-1.21.32.3
Locomotion velocity, hab. session 21.41.95.7-1.2-1.30.50.50.30.21.81.72.0-1.9-1.00.92.4
Novel to familiar place preference ratio2.62.74.8-1.6-1.51.92.02.02.11.11.00.8-1.32.2-2.2-0.3
Novelty place preference2.52.64.8-1.5-1.41.91.92.02.11.01.00.7-1.22.2-2.2-0.4
Time in novel zone, NPP test2.02.13.6-1.4-1.31.71.71.81.81.00.90.7-1.21.9-1.9-0.2
Total zone transitions, NPP test1.31.85.30.40.2-1.1-1.1-1.4-1.40.50.41.1-1.0-2.32.31.8
Total locomotion distance, NPP test1.52.06.3-0.6-0.8-0.3-0.3-0.6-0.71.51.31.9-2.0-1.81.92.5
Locomotion velocity, NPP test1.11.64.8-0.7-0.9-0.0-0.0-0.3-0.31.51.31.9-1.9-1.41.42.2
Intraocular pressure0.50.71.2-0.9-1.00.80.80.70.71.01.10.8-1.00.4-0.10.9
Delta distance traveled before/after self-admin0.70.72.40.50.2-0.8-0.8-1.0-1.00.10.10.6-1.2-1.61.20.8
Delta ambulatory time before/after self-admin1.21.33.31.10.9-1.3-1.3-1.4-1.5-0.5-0.40.0-0.7-1.81.60.4
Parametrial fat weight1.63.14.1-1.9-2.02.02.02.01.91.81.91.8-1.01.4-1.51.1
Pavlov. Cond. lever latency1.31.63.90.80.6-1.4-1.4-1.6-1.40.2-0.21.1-1.5-2.01.71.1
Pavlov. Cond. magazine entry latency2.12.86.3-1.5-1.42.02.02.22.20.70.80.30.42.5-2.3-0.8
Pavlov. Cond. change in total contacts0.80.82.9-0.2-0.10.70.70.81.0-0.4-0.5-0.50.51.7-1.4-1.5
Pavlov. Cond. index score2.63.36.1-1.9-1.82.42.32.52.41.11.30.40.32.4-2.2-0.2
Pavlov. Cond. latency score2.22.85.6-1.6-1.42.12.12.32.20.71.0-0.20.82.4-2.2-0.6
Pavlov. Cond. lever contacts0.70.91.8-0.8-0.71.21.11.31.10.20.5-0.50.81.3-1.2-0.5
Pavlov. Cond. magazine entry number2.22.77.51.21.0-1.9-1.9-2.1-2.2-0.2-0.40.2-0.8-2.72.51.4
Pavlov. Cond. intertrial magazine entries0.60.72.1-0.7-0.80.30.30.20.11.11.01.2-1.5-0.50.51.4
Pavlov. Cond. lever-magazine prob. diff.2.83.56.2-2.0-1.82.42.42.52.41.11.30.50.12.5-2.3-0.3
Pavlov. Cond. response bias2.02.46.0-1.3-1.11.91.92.02.10.40.6-0.20.72.4-2.3-1.0
Pavlov. Cond. lever latency1.11.54.91.01.1-0.5-0.6-0.3-0.4-1.6-1.3-2.12.20.7-0.4-1.6
Pavlov. Cond. magazine entry latency1.61.94.01.21.1-1.7-1.7-1.8-1.7-0.4-0.80.3-0.8-2.01.90.4
Pavlov. Cond. change in total contacts0.60.82.60.20.0-0.7-0.7-0.9-0.70.50.11.3-1.6-1.41.10.8
Pavlov. Cond. index score0.60.82.90.20.0-0.6-0.6-0.8-0.60.60.11.4-1.7-1.21.00.8
Pavlov. Cond. latency score0.70.83.10.1-0.1-0.5-0.5-0.7-0.60.70.31.5-1.8-1.21.11.0
Pavlov. Cond. lever contacts1.52.05.7-1.3-1.40.70.70.50.61.91.62.3-2.4-0.80.51.9
Pavlov. Cond. magazine entry number1.31.63.8-1.0-0.81.51.51.61.50.10.6-0.61.32.0-1.8-0.6
Pavlov. Cond. intertrial magazine entries1.41.82.9-1.6-1.51.61.61.51.41.51.71.1-1.00.9-0.81.1
Pavlov. Cond. lever-magazine prob. diff.0.70.82.70.30.2-0.8-0.8-0.9-0.70.4-0.01.3-1.6-1.31.10.7
Pavlov. Cond. response bias0.71.03.8-0.4-0.6-0.1-0.1-0.3-0.21.10.71.7-1.9-1.20.91.3
Time in closed arm before self-admin0.40.41.00.30.4-0.3-0.3-0.10.1-0.8-0.9-0.91.00.4-1.0-0.9
Time in closed arm after self-admin1.61.64.71.21.2-0.5-0.5-0.3-0.3-1.7-1.4-2.02.20.6-0.9-1.7
Time in open arm before self-admin0.20.21.50.30.2-0.1-0.2-0.2-0.6-0.00.3-0.20.2-0.21.20.4
Time in open arm after self-admin0.30.31.20.1-0.0-0.4-0.4-0.5-0.50.30.10.5-0.7-0.71.10.5
Bone: periosteal estimation1.93.95.8-2.4-2.42.22.22.12.12.22.21.8-1.51.4-1.31.5
Bone: periosteal perimeter2.94.98.2-2.4-2.32.82.72.92.81.51.70.80.22.8-2.70.0
Bone: post-yield work0.20.30.9-0.0-0.1-0.3-0.3-0.4-0.40.40.40.6-0.5-0.90.90.9
Progressive ratio test 1 active lever presses1.21.32.0-1.4-1.41.21.21.11.01.31.41.1-1.00.6-0.71.1
Progressive ratio test 1 breakpoint1.61.62.6-1.6-1.61.31.31.21.21.41.51.2-1.10.5-0.91.2
Progressive ratio test 1 inactive lever presses2.73.04.4-2.1-2.01.71.71.61.62.12.02.0-1.80.6-0.81.5
Progressive ratio test 2 active lever presses0.40.40.6-0.7-0.60.80.80.80.70.50.70.3-0.30.7-0.70.4
Progressive ratio test 2 breakpoint0.50.51.0-0.8-0.80.80.80.80.60.81.00.5-0.70.5-0.40.8
Progressive ratio test 2 inactive lever presses0.40.51.0-0.6-0.50.80.80.80.80.50.60.6-0.31.0-0.90.1
Incentive Sensitization - Responses0.10.10.4-0.4-0.40.50.50.50.40.20.4-0.10.10.2-0.60.2
Incentive Sensitization - Breakpoint0.10.10.4-0.3-0.30.40.40.40.40.10.3-0.20.10.3-0.60.0
Sum of active levers in priming session hrs 5-60.80.82.3-0.5-0.50.70.70.71.20.5-0.01.0-0.91.5-1.5-0.5
Progressive ratio0.40.40.80.80.9-0.7-0.7-0.7-0.7-0.7-0.8-0.60.1-0.10.4-0.7
Food seeking constrained by brief footshock0.20.30.80.50.6-0.3-0.3-0.2-0.1-0.7-0.8-0.30.20.5-0.4-0.9
Seeking ratio, punishment vs. effort0.20.20.6-0.5-0.50.40.40.30.40.50.50.8-0.3-0.1-0.10.5
Retroperitoneal fat weight4.615.021.6-4.5-4.64.24.13.94.04.44.24.2-3.72.3-2.52.8
Reaction time number correct2.63.810.3-0.7-1.1-0.5-0.5-0.9-0.92.01.72.3-3.2-2.72.63.1
Reaction time mean minus median0.30.41.30.40.4-0.0-0.10.10.0-0.7-0.6-1.01.20.3-0.5-0.9
Reaction time mean minus median AUC0.10.10.40.10.00.20.20.30.1-0.10.1-0.50.70.0-0.1-0.2
Reaction time num false alarms0.20.30.40.50.7-0.6-0.6-0.6-0.5-0.5-0.7-0.30.6-0.40.2-0.4
Reaction time num false alarms AUC0.50.71.10.91.0-1.0-1.0-1.0-1.0-0.7-0.9-0.60.9-0.70.7-0.4
Reaction time trials correct on left2.63.810.3-0.7-1.1-0.5-0.5-0.9-0.92.01.72.3-3.2-2.72.63.1
Reaction time trials on left2.83.910.7-0.7-1.1-0.5-0.5-0.9-0.92.01.72.3-3.3-2.72.73.1
Reaction time mean0.30.40.7-0.8-0.80.50.50.50.50.80.70.8-0.8-0.1-0.10.6
Reaction time mean AUC0.40.51.0-0.8-0.80.40.40.30.31.00.80.9-1.0-0.50.31.0
Median of all reaction times0.40.61.3-0.9-0.90.50.50.40.41.00.81.1-1.1-0.30.10.9
Reaction time omissions0.20.30.7-0.4-0.50.30.30.20.10.90.60.8-0.7-0.40.30.7
Reaction time false alarm rate1.21.75.41.11.4-0.7-0.7-0.5-0.4-1.6-1.6-1.72.30.7-0.7-1.9
Reaction time premature initiation rate1.21.62.81.61.7-1.5-1.4-1.4-1.3-1.4-1.5-0.80.7-0.60.8-1.0
Reaction time premature initiations1.21.84.31.10.9-1.5-1.5-1.7-1.6-0.2-0.40.6-1.1-2.02.10.7
Std. dev. reaction times0.20.30.80.50.5-0.7-0.7-0.7-0.7-0.4-0.5-0.50.4-0.90.6-0.2
Reaction time trials completed2.83.910.7-0.7-1.1-0.5-0.5-0.9-0.92.01.72.3-3.3-2.72.73.1
Reaction time trials AUC2.84.011.0-0.8-1.1-0.4-0.4-0.8-0.92.11.72.4-3.3-2.72.63.1
Run reversals in cocaine runway, females0.80.83.00.50.3-1.1-1.1-1.2-1.1-0.1-0.40.0-0.3-1.71.30.5
Run reversals in cocaine runway, males1.41.44.0-0.9-0.81.41.41.51.50.40.5-0.10.12.0-1.8-0.5
Latency to leave start box in cocaine runway0.30.30.90.30.3-0.6-0.6-0.6-0.6-0.3-0.2-0.40.5-1.00.70.1
Latency to leave start box in cocaine runway, F0.50.51.80.20.2-0.7-0.7-0.8-0.90.10.10.10.1-1.31.40.7
Latency to leave start box in cocaine runway, M0.10.10.3-0.2-0.10.20.30.30.3-0.20.0-0.40.20.1-0.6-0.1
Std. dev. time between licks in bursts2.02.47.1-1.1-1.40.30.3-0.0-0.12.01.82.2-2.1-1.61.52.7
Total sessions with >9 infusions0.20.20.40.40.5-0.4-0.4-0.4-0.6-0.4-0.2-0.60.5-0.50.40.0
Short access day 1 total inactive lever presses0.20.21.2-0.1-0.1-0.1-0.1-0.2-0.50.50.60.40.1-0.41.10.9
Short access day 10 total inactive lever presses2.83.24.7-2.0-1.82.12.22.12.21.71.81.4-1.51.5-1.60.8
Short access day 1 total infusions1.31.41.91.31.4-1.3-1.4-1.3-1.4-1.3-1.3-1.11.0-0.70.9-0.8
Short access day 10 total infusions0.50.61.2-0.9-0.80.90.90.90.90.60.70.3-0.50.8-1.10.3
Short access total infusions0.00.00.0-0.1-0.00.00.00.0-0.0-0.10.0-0.10.1-0.1-0.20.1
Short access day 1 locomotion0.40.51.10.70.8-0.4-0.5-0.3-0.5-0.9-0.8-1.00.90.1-0.0-0.8
Short access day 10 total locomotion0.40.51.20.50.60.0-0.00.10.1-0.8-0.7-0.90.91.1-0.6-1.0
Short access total locomotion0.60.61.70.60.9-0.4-0.4-0.3-0.4-1.0-0.8-1.31.20.4-0.2-0.8
One hour access (0.3 mA shock)1.41.72.5-1.6-1.51.31.31.21.21.51.61.2-1.40.5-0.81.3
Compulsive drug intake0.50.50.9-0.8-0.90.60.60.50.61.00.71.0-0.90.1-0.50.7
One hour access (shock baseline)0.20.30.7-0.5-0.50.50.50.40.20.60.80.3-0.3-0.00.30.8
Social response proportion0.40.50.90.90.5-0.8-0.8-0.8-0.9-0.3-0.4-0.3-0.5-0.91.00.1
Social responses0.10.10.30.20.0-0.3-0.4-0.4-0.50.1-0.0-0.0-0.6-0.40.60.3
Social time0.10.10.40.20.1-0.4-0.4-0.4-0.40.0-0.1-0.3-0.6-0.50.60.3
Soleus weight1.23.55.2-2.3-2.32.12.12.01.92.12.31.9-1.01.0-1.01.6
Bone: stiffness0.71.11.7-1.3-1.31.21.11.11.01.21.31.1-0.60.8-0.51.0
Tibialis anterior weight0.10.31.3-0.3-0.40.10.1-0.0-0.10.60.70.5-0.6-0.70.71.1
Time to tail flick, vehicle, before self-admin0.10.10.2-0.5-0.40.20.20.20.10.30.4-0.30.1-0.10.10.4
Time to tail flick, vehicle, after self-admin2.02.22.91.71.5-1.6-1.6-1.6-1.7-1.6-1.3-1.61.7-1.11.1-0.7
Time to tail flick, test, before self-admin0.10.10.40.30.20.30.40.40.4-0.20.0-0.10.40.6-0.6-0.3
Time to tail flick, test, after self-admin0.20.20.70.80.7-0.4-0.4-0.4-0.5-0.5-0.5-0.50.20.3-0.1-0.6
Delta time to tail flick, vehicle, before/after SA0.30.30.90.70.5-0.6-0.6-0.7-0.8-0.2-0.20.2-0.3-0.80.90.2
Delta time to tail flick, test, before/after SA0.50.50.90.80.7-0.6-0.7-0.6-0.6-0.8-0.9-0.90.30.1-0.0-0.9
Tibia length7.721.635.2-5.3-5.05.85.85.95.83.64.22.8-1.05.1-5.00.8
Ambulatory time before self-admin2.42.44.2-1.7-1.61.81.81.82.01.31.01.0-1.01.8-2.00.1
Ambulatory time after self-admin0.50.62.4-0.7-0.90.50.50.50.50.90.70.9-1.50.1-0.50.6
Bone: tissue strength1.61.62.7-1.4-1.51.11.11.00.91.61.61.6-1.40.2-0.21.5
Total heroin consumption0.50.53.00.20.20.30.30.40.6-0.1-0.6-0.10.11.7-1.3-1.1
Bone: trabecular number0.00.00.0-0.1-0.10.10.10.1-0.00.10.20.1-0.1-0.10.10.2
Bone: trabecular spacing1.51.95.9-0.7-0.9-0.0-0.1-0.3-0.31.71.31.9-2.4-1.31.42.3
Bone: trabecular thickness1.01.23.5-0.4-0.20.91.01.11.2-0.4-0.3-0.61.01.7-1.9-1.5
Bone: trabecular tissue density0.81.11.51.21.2-1.2-1.2-1.2-1.1-1.1-1.1-0.91.2-0.80.8-0.6
Water consumed over 24 hours0.30.41.30.30.40.10.10.20.2-0.7-0.6-1.00.80.8-0.7-1.1
Number of responses in last shaping day1.01.02.2-0.9-1.11.11.11.00.81.31.31.5-0.80.5-0.30.7