Hub : Genes

Osbpl9

oxysterol binding protein-like 9

chr5:129047776–129190838 (-)

Osbpl9 RatGTEx page

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Osbpl9 0.45 0.18 0.0e+00 0.19 0.22 0.22 0.22 7.8e-21 2.7e-24 1.7e-24 2.0e-24
2 NAcc gene expression Osbpl9 0.06 0.04 2.8e-05 0.01 0.02 0.03 0.02 1.9e-02 3.6e-04 1.0e-04 3.7e-04
3 Liver alternative TSS XM_039109559.2 0.04 0.03 2.8e-03 0 0 0.01 0.01 3.3e-01 2.1e-01 3.0e-02 6.8e-02
4 pVTA intron excision ratio chr5_129119623_129120517 0.03 0.03 4.8e-03 0.03 0.02 0.03 0.03 8.4e-04 1.4e-02 1.5e-03 1.7e-03
5 Liver intron excision ratio chr5_129087292_129103184 0.04 0.03 2.1e-03 0.01 0.01 0.01 0.01 1.2e-02 4.7e-02 6.0e-02 3.4e-02
6 Liver mRNA stability Osbpl9 0.04 0.03 1.8e-03 0.02 0.01 0.01 0.01 5.4e-03 2.1e-02 1.6e-02 1.3e-02
7 Liver alternative TSS XM_039109564.2 0.04 0.03 6.4e-04 0.01 0.01 0.01 0.01 9.3e-03 1.1e-02 1.8e-02 2.0e-02
8 Brain gene expression Osbpl9 0.14 0.09 1.4e-08 0.07 0.1 0.09 0.09 2.6e-07 2.5e-09 2.1e-08 8.2e-09
9 PL intron excision ratio chr5_129119623_129147542 0.03 0.02 3.7e-03 0 0.01 0.01 0.01 2.2e-01 4.7e-02 2.5e-02 3.1e-02
10 pVTA gene expression Osbpl9 0.07 0.09 2.1e-04 0.05 0.05 0.05 0.05 8.5e-05 8.7e-05 7.3e-05 5.3e-05
11 Liver alternative TSS XM_039109564.2 0.07 0.05 9.6e-05 0 0.02 0.01 0.01 3.0e-01 2.9e-03 9.9e-03 4.0e-02
12 Liver intron excision ratio chr5_129087292_129119547 0.06 0.04 4.2e-04 0.01 0.02 0.02 0.02 2.8e-02 9.6e-04 1.3e-03 4.2e-03
13 IC gene expression Osbpl9 0.22 0.14 4.3e-04 0.09 0.09 0.08 0.09 1.7e-04 1.0e-04 2.6e-04 1.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.40.82.0-0.8-0.6-1.11.01.0-1.01.0-0.6-1.2-1.40.3-0.30.1
Area under the delay curve0.20.20.7-0.5-0.8-0.1-0.00.1-0.10.1-0.70.2-0.20.8-0.8-0.8
BMI with tail1.45.06.72.62.42.5-2.6-2.32.3-2.52.32.02.1-2.01.91.0
BMI without tail0.72.12.81.51.41.7-1.7-1.61.6-1.71.41.51.5-1.11.00.4
Body weight0.73.24.22.11.82.0-2.1-1.71.7-2.01.91.72.0-1.61.50.8
Weight adjusted by age0.50.71.41.01.10.7-0.6-0.70.7-0.61.20.40.6-1.21.21.0
Bone surface0.30.50.8-0.7-0.7-0.80.70.6-0.60.7-0.7-0.7-0.90.6-0.6-0.4
Bone volume0.00.10.3-0.2-0.1-0.30.20.1-0.10.2-0.2-0.3-0.60.1-0.1-0.0
Breakpoint value in progressive ratio session0.00.00.10.00.1-0.10.10.1-0.10.10.1-0.3-0.2-0.10.20.2
Number of licking bursts0.20.40.70.80.80.5-0.5-0.30.3-0.50.80.10.2-0.80.80.7
Context. condit. distance diff. score0.20.20.7-0.3-0.1-0.40.70.8-0.80.5-0.0-0.3-0.4-0.20.20.5
Locomotion velocity, session 12.02.14.5-1.2-0.6-1.81.82.0-2.01.8-0.6-2.1-1.80.10.00.9
Locomotion distance, session 10.10.10.30.10.3-0.10.10.4-0.40.10.3-0.30.0-0.40.40.6
Locomotion velocity, session 21.82.14.2-1.1-0.5-1.71.82.0-2.01.7-0.5-2.0-1.9-0.00.11.0
Locomotion distance, session 20.30.41.00.2-0.10.7-0.8-0.50.5-0.7-0.11.00.60.4-0.5-0.9
Locomotion velocity, session 30.60.71.2-0.9-0.6-1.01.01.1-1.11.0-0.6-1.1-1.00.4-0.40.0
Locomotion distance, session 30.20.20.8-0.3-0.40.1-0.1-0.10.1-0.1-0.50.60.40.7-0.7-0.9
Stereotopy head waving bouts, day 30.10.10.40.30.5-0.3-0.0-0.10.10.30.3-0.7-0.3-0.40.40.6
Stereotopy head waving duration, day 30.50.72.10.30.8-0.60.30.4-0.40.60.6-1.3-0.7-1.01.01.4
Locomotion velocity, session 70.80.81.6-0.9-1.1-0.20.50.7-0.70.4-1.10.9-0.61.3-1.3-1.3
Locomotion distance, session 71.51.95.6-1.3-1.8-0.10.40.4-0.40.3-1.81.4-0.22.1-2.1-2.4
Stereotopy head waving bouts, day 71.11.32.9-0.8-0.3-1.61.31.2-1.21.6-0.5-1.7-1.60.2-0.10.6
Stereotopy head waving duration, day 71.11.33.5-0.8-0.2-1.61.31.3-1.31.5-0.4-1.9-1.5-0.00.10.8
Locomotion velocity, session 81.51.83.6-1.3-1.1-1.51.71.9-1.91.6-1.1-1.0-1.70.7-0.7-0.0
Locomotion distance, session 80.10.10.4-0.3-0.3-0.00.20.6-0.60.1-0.30.4-0.10.3-0.3-0.2
Degree of sensitization distance0.20.20.9-0.2-0.40.4-0.1-0.10.1-0.3-0.30.90.10.5-0.6-0.8
Degree of sensitization stereotypy0.60.61.3-0.6-0.3-1.00.90.9-0.91.0-0.4-1.2-1.00.2-0.10.3
Conditioned locomotion0.60.61.60.91.10.5-0.4-0.30.3-0.41.10.10.1-1.21.21.3
Cocaine response after cond. corrected1.01.22.30.70.31.3-1.5-1.31.3-1.40.21.41.50.2-0.3-1.1
Cocaine response after cond. not corrected1.41.63.11.10.71.5-1.8-1.61.6-1.60.71.51.6-0.20.1-0.6
Cocaine response before conditioning0.30.30.60.60.70.3-0.3-0.50.5-0.20.70.00.1-0.70.80.8
Saline control response1.01.34.0-0.9-1.4-0.00.10.3-0.30.2-1.41.3-0.21.7-1.7-2.0
Bone: connectivity density1.21.82.8-1.4-1.3-1.51.41.5-1.51.4-1.3-1.5-1.71.1-1.0-0.5
Bone: cortical apparent density1.21.64.4-1.1-0.6-1.61.61.3-1.31.6-0.6-1.7-2.10.2-0.10.6
Bone: cortical area0.81.23.21.10.61.5-1.4-1.11.1-1.40.61.81.4-0.30.2-0.4
Bone: cortical porosity1.01.13.80.91.30.0-0.0-0.10.1-0.01.3-0.9-0.3-1.61.71.9
Bone: cortical porosity0.70.82.90.50.8-0.30.40.4-0.40.40.9-1.0-0.7-1.21.31.7
Bone: cortical thickness2.23.65.92.11.72.3-2.2-2.12.1-2.21.62.42.2-1.21.10.3
Bone: cortical thickness2.32.73.81.91.71.8-1.7-1.91.9-1.71.61.61.6-1.41.40.9
Bone: cortical tissue density1.31.74.8-1.1-0.6-1.61.71.4-1.41.7-0.6-1.8-2.20.1-0.00.7
Condit. Reinf. active minus inactive responses0.30.40.80.70.60.6-0.8-0.90.9-0.60.40.60.6-0.30.2-0.0
Condit. Reinf. active-inactive response ratio0.60.71.20.80.60.9-0.9-1.11.1-0.90.60.91.1-0.40.40.0
Condit. Reinf. active responses0.70.91.51.00.81.1-1.2-1.21.2-1.10.71.01.0-0.50.4-0.0
Condit. Reinf. inactive responses0.10.10.3-0.0-0.20.4-0.2-0.10.1-0.5-0.00.60.30.2-0.2-0.4
Incentive salience index mean1.21.52.51.31.11.4-1.6-1.61.6-1.41.01.21.4-0.80.70.1
Condit. Reinf. lever presses1.31.82.81.41.21.6-1.7-1.51.5-1.71.21.31.6-0.80.80.1
Condit. Reinf. active minus inactive responses0.50.72.7-0.2-0.60.6-0.4-0.60.6-0.5-0.61.60.10.9-1.0-1.3
Condit. Reinf. active-inactive response ratio0.30.31.1-0.4-0.70.2-0.0-0.10.1-0.1-0.61.0-0.20.8-0.9-1.0
Condit. Reinf. active responses0.20.31.50.2-0.10.7-0.5-0.70.7-0.5-0.11.20.20.3-0.3-0.6
Condit. Reinf. inactive responses0.40.50.80.70.70.7-0.7-0.90.9-0.70.70.50.4-0.60.60.4
Condit. Reinf. lever presses0.91.22.9-1.3-1.5-0.60.60.5-0.50.5-1.50.0-0.71.6-1.7-1.7
Condit. Reinf. lever reinforcers received0.20.31.3-0.1-0.40.5-0.3-0.50.5-0.5-0.31.10.10.6-0.6-0.9
Conditioned reinforcement - actives1.22.05.10.70.11.7-1.7-1.81.8-1.70.02.21.70.5-0.6-1.5
Conditioned reinforcement - inactives0.00.10.10.30.30.3-0.3-0.20.2-0.30.20.30.3-0.20.20.0
Conditioned locomotion0.50.71.70.50.21.0-1.0-1.01.0-1.00.21.31.10.1-0.2-0.7
Patch foraging indifference point 0 sec0.20.30.60.60.40.7-0.7-0.70.7-0.70.40.80.5-0.20.2-0.2
Patch foraging indifference point AUC0.20.20.4-0.5-0.4-0.60.60.6-0.60.6-0.4-0.6-0.50.3-0.3-0.1
Delay disc. indifference point, 0s delay0.80.91.7-1.0-1.3-0.60.30.8-0.80.6-1.2-0.1-0.61.3-1.3-1.2
Delay disc. indifference point, 16s delay0.70.81.70.80.41.1-1.3-1.11.1-1.10.51.11.0-0.30.2-0.3
Delay disc. indifference point, 2s delay0.10.10.2-0.4-0.5-0.20.10.3-0.30.2-0.40.1-0.30.4-0.4-0.4
Delay disc. indifference point, 24s delay0.20.20.4-0.6-0.6-0.30.30.2-0.20.4-0.60.1-0.50.6-0.5-0.4
Delay disc. indifference point, 4s delay0.10.10.2-0.1-0.20.2-0.1-0.40.4-0.2-0.20.3-0.00.3-0.3-0.4
Delay disc. indifference point, 8s delay0.10.10.4-0.3-0.6-0.0-0.20.1-0.10.0-0.50.3-0.10.6-0.6-0.6
Indifference point function ln k0.20.40.70.70.50.9-0.8-0.70.7-0.80.60.80.6-0.40.40.0
Indifference point function log k0.20.40.70.70.50.9-0.8-0.70.7-0.80.60.80.6-0.40.40.0
Patch foraging total patch changes 0 sec0.20.30.50.60.50.6-0.7-0.70.7-0.60.40.70.4-0.30.3-0.0
Patch foraging total patch changes 12 sec0.81.01.6-1.1-0.8-1.31.21.1-1.11.3-0.9-1.0-1.20.7-0.6-0.1
Patch foraging total patch changes 18 sec0.10.20.30.40.40.5-0.5-0.60.6-0.60.30.50.5-0.20.2-0.0
Patch foraging total patch changes 24 sec0.61.01.41.21.11.1-1.1-1.11.1-1.11.01.01.0-0.90.80.4
Patch foraging total patch changes 6 sec0.10.20.8-0.2-0.40.1-0.2-0.20.2-0.1-0.50.60.10.6-0.7-0.9
Patch foraging time to switch 0 sec0.61.22.5-1.0-0.6-1.41.31.4-1.41.4-0.6-1.6-1.30.3-0.20.4
Patch foraging water rate 0 sec1.22.53.51.71.51.9-1.8-1.91.9-1.81.51.71.5-1.21.10.4
Patch foraging water rate 12 sec1.22.54.11.61.21.9-2.0-1.81.8-1.91.22.02.0-0.70.6-0.2
Patch foraging water rate 18 sec0.10.10.40.30.40.1-0.0-0.30.3-0.00.4-0.0-0.3-0.50.50.6
Patch foraging water rate 24 sec0.10.20.40.50.60.2-0.1-0.10.1-0.20.6-0.0-0.1-0.70.70.7
Patch foraging water rate 6 sec1.01.52.31.31.11.5-1.5-1.41.4-1.51.11.41.0-0.90.80.3
Seeking ratio, delayed vs. immediate footshock1.62.03.91.41.01.9-1.8-1.41.4-1.81.02.01.8-0.60.5-0.3
Distance traveled before self-admin0.30.30.70.60.70.4-0.4-0.40.4-0.50.8-0.20.4-0.80.80.7
Distance traveled after self-admin0.81.01.41.21.01.1-1.1-1.11.1-1.21.10.70.9-1.00.90.5
Extensor digitorum longus weight1.45.38.22.62.52.4-2.4-2.92.9-2.32.41.81.9-2.12.11.3
Bone: elastic displacement0.60.71.70.81.10.3-0.3-0.40.4-0.31.1-0.50.4-1.21.21.3
Bone: elastic work0.20.20.30.50.60.4-0.4-0.40.4-0.40.50.30.5-0.50.50.4
Bone: endosteal estimation0.10.30.8-0.5-0.5-0.60.40.6-0.60.4-0.4-0.9-0.30.4-0.4-0.3
Bone: endosteal perimeter0.51.11.8-1.2-1.3-1.00.80.9-0.90.8-1.2-0.8-0.71.3-1.3-1.2
Epididymis fat weight0.10.51.0-0.9-1.0-0.40.40.6-0.60.4-0.9-0.1-0.31.0-1.0-0.9
Delta time in closed arm before/after self-admin0.00.00.1-0.1-0.20.0-0.00.0-0.00.0-0.20.2-0.10.2-0.2-0.3
Delta time in open arm before/after self-admin0.10.10.20.10.10.2-0.3-0.40.4-0.30.10.00.20.0-0.0-0.2
Diff in mean of infusions in LGA sessions0.30.31.0-0.4-0.70.2-0.0-0.10.1-0.1-0.70.80.00.8-0.9-1.0
Delay discount exponential model param0.20.20.70.50.70.10.0-0.00.0-0.10.7-0.30.2-0.80.80.8
Extinction: sum of active levers before priming0.80.92.21.01.40.3-0.4-0.30.3-0.31.3-0.50.3-1.41.51.5
Active lever presses in extinction session 61.11.12.30.70.21.3-1.2-1.41.4-1.40.31.51.30.1-0.2-0.9
Bone: final force0.10.20.3-0.4-0.6-0.20.20.3-0.30.2-0.5-0.00.10.6-0.6-0.6
Bone: final moment0.10.10.4-0.3-0.5-0.10.00.1-0.10.0-0.40.20.30.5-0.6-0.7
Food consumed during 24 hour testing period1.01.45.0-0.7-1.20.5-0.3-0.60.6-0.5-1.21.50.51.6-1.7-2.2
Glucose0.10.20.6-0.0-0.30.3-0.3-0.40.4-0.4-0.30.70.40.5-0.5-0.8
Heart weight2.03.14.52.02.11.7-1.6-1.71.7-1.62.11.11.4-2.01.91.5
Delay discount hyperbolic model param0.20.20.50.50.70.1-0.0-0.10.1-0.10.6-0.20.3-0.70.70.7
Intermittent access intake day 1-15 change0.20.41.10.40.10.8-0.9-0.70.7-0.80.11.00.80.2-0.2-0.7
Intermittent access intake escalation0.20.40.90.60.40.8-0.9-0.70.7-0.80.41.00.8-0.20.1-0.3
Intermittent access intake escalation 20.10.10.20.30.20.4-0.4-0.30.3-0.40.10.50.30.0-0.0-0.2
Intermitt. access day 1 inactive lever presses0.41.52.71.10.71.5-1.4-1.61.6-1.50.71.61.5-0.40.3-0.3
Intermitt. access day 15 inactive lever presses0.51.01.41.21.11.1-1.0-1.01.0-1.01.10.90.8-1.01.00.6
Intermitt. access escalation Index0.10.20.70.30.40.00.1-0.00.00.00.5-0.30.0-0.70.70.8
Intermittent access day 1 total infusions0.10.20.60.30.6-0.10.10.0-0.00.10.5-0.4-0.2-0.60.60.8
Intermittent access day 15 total infusions0.30.50.80.80.90.6-0.7-0.70.7-0.60.80.50.6-0.70.70.5
Intermittent access terminal intake (last 3 days)0.10.10.30.40.50.2-0.2-0.30.3-0.20.40.10.2-0.40.40.3
Intermittent access total infusions0.10.20.40.40.6-0.0-0.1-0.10.10.00.5-0.2-0.1-0.60.60.7
Intermittent access day 1 locomotion0.10.10.30.30.40.0-0.0-0.10.10.00.4-0.2-0.0-0.40.50.5
Intermittent access day 15 total locomotion0.10.20.40.1-0.10.4-0.4-0.50.5-0.4-0.20.60.50.4-0.4-0.7
Intermittent access total locomotion0.10.20.40.50.70.2-0.2-0.20.2-0.10.6-0.00.1-0.60.60.6
Intermittent access standard deviation1.02.13.51.41.11.8-1.8-1.71.7-1.71.01.91.8-0.60.6-0.2
Left kidney weight4.018.628.04.53.55.2-5.2-5.05.0-5.13.55.25.3-2.52.20.1
Right kidney weight2.511.416.93.73.04.0-4.1-3.73.7-3.93.03.84.1-2.32.10.6
Cocaine induced anxiety1.11.63.41.51.81.0-0.8-0.90.9-0.81.60.60.8-1.71.61.4
Post-drug Anxiety2.52.75.31.92.31.2-1.0-1.21.2-1.02.20.71.0-2.22.21.9
Baseline Anxiety0.10.10.30.30.10.4-0.4-0.50.5-0.40.30.40.4-0.20.20.0
Tail length0.00.00.1-0.0-0.0-0.10.20.3-0.30.10.0-0.20.1-0.10.10.1
Length with tail0.10.31.00.60.30.7-0.7-0.50.5-0.70.40.91.0-0.20.1-0.3
Length without tail0.82.65.91.50.82.1-2.1-1.71.7-2.00.92.42.1-0.40.2-0.7
LgA early post infusion interval1.11.42.01.41.41.2-1.2-1.41.4-1.31.40.50.9-1.21.20.8
LgA late post infusion interval0.10.20.30.40.40.4-0.4-0.60.6-0.50.40.20.4-0.40.30.2
LgA early loading1.01.93.4-1.4-1.1-1.71.61.8-1.81.7-1.1-1.7-1.30.7-0.70.0
LgA late loading0.81.83.5-1.3-1.0-1.71.51.7-1.71.6-1.0-1.9-1.40.7-0.60.1
LgA early average infusions1.82.33.8-1.5-1.3-1.81.81.9-1.91.8-1.3-1.6-1.40.9-0.8-0.1
LgA late average infusions0.81.12.1-1.1-0.8-1.31.31.4-1.41.3-0.8-1.2-1.10.6-0.50.0
LgA early timeout0.10.10.20.20.30.10.0-0.10.1-0.00.30.00.5-0.30.40.4
LgA late timeout0.50.61.80.60.40.9-1.0-1.01.0-1.10.40.81.3-0.10.0-0.4
LgA early titration2.33.25.4-1.8-1.4-2.22.12.3-2.32.1-1.4-2.1-1.81.0-0.90.0
LgA late titration2.23.35.4-1.9-1.7-2.12.12.3-2.32.1-1.7-1.7-1.91.3-1.2-0.4
LgA total infusion2.53.55.6-1.9-1.6-2.22.32.4-2.42.3-1.6-1.8-2.01.2-1.1-0.2
Times rat made contact with spout0.60.73.0-0.4-0.80.3-0.5-0.50.5-0.4-0.80.80.41.2-1.3-1.7
Lifetime Intake0.00.00.00.10.2-0.10.0-0.00.00.10.1-0.1-0.1-0.10.10.1
Liver weight, left0.20.40.8-0.8-0.9-0.40.50.2-0.20.4-0.80.0-0.10.9-0.9-0.9
Liver weight, right0.30.61.0-0.8-1.0-0.50.60.7-0.70.5-0.9-0.1-0.21.0-1.0-0.9
Locomotor activity0.60.93.1-0.8-1.2-0.10.20.0-0.00.0-1.20.6-0.11.5-1.5-1.8
Locomotor testing distance0.50.93.4-0.5-1.00.4-0.2-0.20.2-0.4-1.01.00.41.3-1.4-1.8
Locomotor testing rearing0.71.55.5-0.9-1.50.1-0.20.0-0.0-0.2-1.51.10.11.9-1.9-2.3
Locomotion in novel chamber1.82.34.11.10.51.9-2.0-1.91.9-2.00.52.02.00.1-0.2-1.2
Locomotion in novel chamber post-restriction0.71.12.41.21.50.5-0.6-0.40.4-0.61.4-0.40.7-1.51.51.5
Fecal boli incidents, locomotor time 10.30.41.1-0.4-0.70.1-0.20.1-0.1-0.1-0.70.80.10.9-0.9-1.1
Change in fecal boli incidents, locomotor task0.40.40.7-0.6-0.7-0.60.70.9-0.90.6-0.6-0.5-0.70.5-0.5-0.3
Time >=10cm from walls, locomotor time 11.01.13.1-0.30.2-1.21.11.2-1.21.10.2-1.8-1.3-0.60.71.2
Bouts of movement, locomotor time 10.91.01.5-1.2-1.0-1.11.20.8-0.81.0-1.1-1.2-0.71.0-0.9-0.6
Total resting periods, locomotor time 10.50.61.4-0.9-0.7-0.91.10.6-0.60.8-0.7-1.2-0.60.6-0.6-0.3
Rest time, locomotor task time 10.20.30.6-0.6-0.7-0.30.40.3-0.30.3-0.80.0-0.10.8-0.8-0.8
Distance moved, locomotor task time 10.30.51.60.50.7-0.10.40.3-0.30.10.8-0.6-0.4-1.01.01.3
Vertical activity count, locomotor time 10.20.40.80.70.60.9-0.5-0.50.5-0.90.60.70.5-0.50.50.3
Time >=10cm from walls, locomotor time 20.10.20.60.40.50.2-0.10.2-0.2-0.30.6-0.10.1-0.70.70.8
Bouts of movement, locomotor time 20.20.41.7-0.20.4-0.70.70.1-0.10.60.2-1.3-0.5-0.50.50.9
Total resting periods, locomotor time 20.20.41.8-0.30.3-0.80.70.0-0.00.70.1-1.3-0.5-0.40.40.8
Rest time, locomotor task time 20.30.40.7-0.7-0.8-0.60.30.1-0.10.6-0.8-0.2-0.50.8-0.8-0.7
Distance moved, locomotor task time 21.01.21.81.31.21.3-0.8-0.70.7-1.31.30.71.3-1.21.20.9
Vertical activity count, locomotor time 21.21.63.41.20.81.9-1.2-1.31.3-1.80.91.71.8-0.60.5-0.1
Light reinforcement 10.20.51.00.91.00.5-0.6-0.40.4-0.51.00.10.6-1.01.00.9
Light reinforcement 21.21.92.51.61.41.5-1.6-1.31.3-1.51.51.21.5-1.31.20.7
Bone: marrow area0.10.20.8-0.4-0.4-0.50.30.5-0.50.3-0.3-0.9-0.20.3-0.3-0.2
Bone: maximum diameter0.10.20.30.60.50.4-0.5-0.30.3-0.50.50.20.5-0.50.50.3
Bone: maximum force0.00.10.3-0.3-0.4-0.10.10.1-0.10.1-0.40.10.10.4-0.5-0.5
Bone: maximum moment0.00.10.3-0.1-0.40.1-0.1-0.10.1-0.1-0.30.30.30.4-0.4-0.6
Mean time between licks in bursts1.12.73.6-1.8-1.9-1.61.61.6-1.61.7-1.9-0.6-1.81.8-1.7-1.3
Mean num. licks in bursts0.30.51.8-0.3-0.60.3-0.4-0.60.6-0.4-0.60.80.70.9-1.0-1.4
Cd content in liver0.50.60.8-0.9-0.8-0.80.90.8-0.80.9-0.8-0.4-0.80.7-0.6-0.3
Co content in liver0.10.10.3-0.4-0.5-0.20.2-0.10.10.2-0.50.10.30.5-0.5-0.6
Cu content in liver1.61.94.4-1.5-1.8-0.80.70.6-0.60.7-1.80.2-0.92.0-2.1-2.1
Fe content in liver0.91.11.61.11.30.8-0.9-1.01.0-0.91.2-0.11.2-1.21.21.0
K content in liver2.12.04.6-1.6-1.9-0.80.70.7-0.70.7-1.90.2-0.62.1-2.1-2.1
Mg content in liver1.31.34.9-0.4-1.00.6-0.6-0.50.5-0.6-1.01.60.81.5-1.6-2.2
Mn content in liver0.20.20.4-0.4-0.3-0.50.50.5-0.50.5-0.3-0.5-0.60.2-0.20.1
Na content in liver0.70.71.1-1.0-1.0-0.90.80.7-0.70.8-1.0-0.5-0.71.0-1.0-0.7
Rb content in liver0.30.31.0-0.6-0.7-0.20.2-0.00.00.2-0.80.3-0.10.9-0.9-1.0
Se content in liver0.50.61.2-0.8-1.0-0.40.40.5-0.50.4-1.00.3-0.51.1-1.1-1.1
Sr content in liver0.00.00.00.10.1-0.0-0.00.0-0.0-0.00.1-0.1-0.0-0.20.20.2
Zn content in liver1.92.13.7-1.6-1.9-1.01.11.2-1.21.1-1.90.0-1.11.9-1.9-1.8
Bone: minimum diameter0.30.62.4-0.2-0.70.5-0.6-0.30.3-0.6-0.61.00.61.0-1.1-1.6
Time in familiar zone, hab. session 10.30.30.6-0.4-0.1-0.60.70.6-0.60.7-0.2-0.6-0.8-0.00.10.4
Time in novel zone, hab. session 10.20.20.6-0.5-0.7-0.30.20.1-0.10.2-0.6-0.1-0.20.7-0.7-0.8
Total zone transitions, hab. session 10.20.20.80.30.5-0.30.10.3-0.30.20.5-0.8-0.3-0.60.70.9
Total locomotion distance, hab. session 10.70.91.91.11.30.5-0.7-0.60.6-0.51.3-0.20.5-1.41.41.4
Locomotion velocity, hab. session 10.40.61.30.91.10.3-0.5-0.40.4-0.41.0-0.30.5-1.11.11.1
Time in familiar zone, hab. session 21.21.32.6-1.3-1.5-0.70.80.6-0.60.8-1.50.2-0.71.6-1.6-1.5
Time in novel zone, hab. session 20.50.51.10.70.90.2-0.4-0.30.3-0.30.9-0.50.3-1.01.01.1
Total zone transitions, hab. session 20.20.20.6-0.4-0.5-0.10.00.3-0.30.1-0.60.3-0.00.7-0.7-0.8
Total locomotion distance, hab. session 20.10.20.40.40.40.5-0.6-0.50.5-0.50.20.60.6-0.10.1-0.1
Locomotion velocity, hab. session 20.20.30.50.50.40.6-0.7-0.60.6-0.60.30.70.7-0.20.2-0.1
Novel to familiar place preference ratio0.80.81.50.40.01.1-1.1-1.11.1-1.20.11.21.20.3-0.4-1.1
Novelty place preference0.40.40.80.30.00.8-0.8-0.80.8-0.90.10.80.90.2-0.3-0.8
Time in novel zone, NPP test0.30.30.60.2-0.10.6-0.7-0.70.7-0.7-0.00.60.70.3-0.3-0.8
Total zone transitions, NPP test0.71.01.51.21.11.0-1.1-1.01.0-1.01.10.71.0-1.01.00.7
Total locomotion distance, NPP test0.81.11.61.21.21.0-1.2-1.31.3-1.01.10.71.2-0.90.90.5
Locomotion velocity, NPP test1.31.82.51.51.41.4-1.5-1.61.6-1.41.31.11.5-1.11.00.6
Intraocular pressure0.20.20.60.20.00.5-0.5-0.70.7-0.5-0.00.80.50.2-0.2-0.5
Delta distance traveled before/after self-admin0.90.91.90.90.61.2-1.2-1.31.3-1.20.51.41.1-0.30.2-0.3
Delta ambulatory time before/after self-admin0.50.61.20.70.41.0-1.0-1.01.0-1.00.41.10.9-0.20.1-0.3
Parametrial fat weight0.00.10.20.10.2-0.30.30.3-0.30.30.1-0.4-0.2-0.20.30.4
Pavlov. Cond. lever latency1.62.02.9-1.7-1.6-1.41.71.6-1.61.4-1.4-1.0-1.51.2-1.2-0.7
Pavlov. Cond. magazine entry latency0.20.30.5-0.6-0.5-0.70.60.5-0.50.6-0.6-0.7-0.50.5-0.5-0.3
Pavlov. Cond. change in total contacts0.00.00.00.10.10.1-0.2-0.10.1-0.10.10.0-0.0-0.10.10.0
Pavlov. Cond. index score0.20.30.50.60.60.5-0.7-0.70.7-0.60.50.30.7-0.40.40.2
Pavlov. Cond. latency score0.30.30.70.70.70.5-0.8-0.70.7-0.60.50.40.7-0.40.40.1
Pavlov. Cond. lever contacts1.21.52.11.41.41.1-1.4-1.41.4-1.21.30.71.3-1.11.10.7
Pavlov. Cond. magazine entry number0.20.30.80.50.30.7-0.5-0.50.5-0.60.40.90.4-0.30.20.0
Pavlov. Cond. intertrial magazine entries0.40.51.90.2-0.20.7-0.8-0.60.6-0.7-0.31.40.70.6-0.7-1.1
Pavlov. Cond. lever-magazine prob. diff.0.40.40.80.70.70.6-0.9-0.80.8-0.70.60.40.9-0.50.40.1
Pavlov. Cond. response bias0.10.20.30.50.60.2-0.4-0.40.4-0.30.5-0.20.4-0.50.50.5
Pavlov. Cond. lever latency1.21.75.61.21.70.2-0.2-0.20.2-0.11.7-0.70.3-2.02.12.4
Pavlov. Cond. magazine entry latency3.34.08.1-2.3-2.7-1.31.31.1-1.11.2-2.6-0.2-1.12.8-2.8-2.8
Pavlov. Cond. change in total contacts1.42.36.7-1.5-2.0-0.30.50.5-0.50.3-1.90.8-0.52.3-2.3-2.6
Pavlov. Cond. index score2.83.89.5-2.2-2.6-0.91.00.9-0.90.8-2.60.2-0.82.9-3.0-3.1
Pavlov. Cond. latency score2.73.58.9-2.1-2.5-0.90.90.8-0.80.8-2.50.2-0.82.8-2.8-3.0
Pavlov. Cond. lever contacts1.01.44.4-1.2-1.6-0.30.30.3-0.30.2-1.50.5-0.41.8-1.9-2.1
Pavlov. Cond. magazine entry number4.55.59.42.73.01.8-1.8-1.91.9-1.73.00.71.7-3.13.12.8
Pavlov. Cond. intertrial magazine entries0.50.82.70.81.20.2-0.1-0.30.3-0.11.1-0.3-0.3-1.41.41.6
Pavlov. Cond. lever-magazine prob. diff.3.24.310.7-2.3-2.8-1.01.00.9-0.90.9-2.70.3-0.83.1-3.1-3.3
Pavlov. Cond. response bias2.02.76.3-1.8-2.2-0.80.90.9-0.90.7-2.20.2-0.92.4-2.4-2.5
LgA PC1 addiction-like behavior1.63.04.5-1.9-1.8-1.91.92.1-2.11.9-1.8-1.3-1.71.5-1.5-0.8
Time in closed arm before self-admin0.20.20.5-0.3-0.1-0.60.60.7-0.70.7-0.1-0.5-0.6-0.10.20.5
Time in closed arm after self-admin0.10.10.30.00.2-0.30.40.5-0.50.40.2-0.2-0.5-0.30.40.6
Time in open arm before self-admin0.30.41.2-0.5-0.8-0.00.0-0.00.0-0.1-0.80.3-0.00.9-1.0-1.1
Time in open arm after self-admin0.40.40.90.40.10.7-0.9-0.90.9-0.90.10.50.80.1-0.2-0.7
Bone: periosteal estimation0.10.30.60.60.40.7-0.8-0.50.5-0.80.50.50.8-0.30.2-0.1
Bone: periosteal perimeter0.00.10.3-0.1-0.30.1-0.2-0.00.0-0.2-0.20.20.20.4-0.4-0.6
Bone: post-yield work0.10.10.3-0.4-0.4-0.40.20.4-0.40.2-0.3-0.5-0.10.3-0.3-0.3
Progressive ratio test 1 active lever presses0.60.81.21.11.10.9-1.0-0.90.9-0.91.00.80.9-0.80.80.5
Progressive ratio test 1 breakpoint0.70.81.31.11.10.9-1.0-0.90.9-0.91.00.70.9-0.90.90.5
Progressive ratio test 1 inactive lever presses0.40.60.90.90.90.8-0.7-0.70.7-0.80.90.60.6-0.80.80.5
Progressive ratio test 2 active lever presses0.50.61.00.91.00.8-0.8-0.70.7-0.70.80.60.6-0.70.70.5
Progressive ratio test 2 breakpoint0.60.71.41.11.20.8-0.8-0.80.8-0.71.00.60.6-1.00.90.7
Progressive ratio test 2 inactive lever presses0.00.10.10.30.30.3-0.3-0.30.3-0.20.20.30.1-0.10.1-0.0
ShA PR total presses1.31.52.6-1.1-0.7-1.51.61.6-1.61.6-0.7-1.6-1.30.3-0.20.5
Incentive Sensitization - Responses0.00.00.00.10.20.0-0.1-0.00.0-0.00.10.0-0.1-0.10.10.1
Incentive Sensitization - Breakpoint0.00.00.10.20.30.1-0.1-0.10.1-0.10.10.1-0.0-0.10.10.1
LgA PR total presses0.10.10.30.40.30.4-0.4-0.50.5-0.40.30.20.6-0.20.20.1
Sum of active levers in priming session hrs 5-60.60.61.10.81.10.3-0.4-0.50.5-0.41.0-0.40.3-1.11.11.0
Progressive ratio0.10.20.70.40.10.6-0.6-0.40.4-0.60.20.60.8-0.10.0-0.2
Food seeking constrained by brief footshock1.92.33.9-1.5-1.2-1.91.92.0-2.01.9-1.1-1.8-1.60.7-0.60.2
Seeking ratio, punishment vs. effort1.82.74.3-1.6-1.0-2.12.11.9-1.92.1-1.1-2.0-2.10.7-0.60.3
Retroperitoneal fat weight0.00.20.4-0.3-0.3-0.60.60.7-0.70.6-0.2-0.6-0.50.1-0.10.2
Reaction time number correct0.20.51.50.60.90.1-0.1-0.30.3-0.10.9-0.4-0.3-1.11.11.2
Reaction time mean minus median0.92.36.4-1.6-2.0-0.50.40.2-0.20.5-2.00.6-0.32.3-2.4-2.5
Reaction time mean minus median AUC0.61.64.2-1.4-1.7-0.50.40.3-0.30.5-1.70.4-0.51.9-2.0-2.1
Reaction time num false alarms0.70.92.40.2-0.31.1-0.8-1.01.0-1.1-0.31.51.30.7-0.8-1.4
Reaction time num false alarms AUC1.01.64.30.5-0.11.5-1.3-1.41.4-1.5-0.12.11.70.6-0.7-1.5
Reaction time trials correct on left0.20.51.50.60.90.1-0.1-0.30.3-0.10.9-0.4-0.3-1.11.11.2
Reaction time trials on left0.20.41.20.50.80.1-0.1-0.30.3-0.10.8-0.3-0.3-0.91.01.1
Reaction time mean1.11.84.0-1.5-1.8-0.70.60.8-0.80.6-1.80.1-0.72.0-2.0-2.0
Reaction time mean AUC1.01.73.3-1.5-1.7-0.80.80.9-0.90.8-1.7-0.2-0.91.8-1.8-1.7
Median of all reaction times0.91.22.2-1.2-1.5-0.70.70.9-0.90.6-1.4-0.2-0.81.5-1.5-1.4
Reaction time omissions1.11.55.5-1.0-1.50.1-0.2-0.10.1-0.1-1.51.20.11.9-2.0-2.3
Reaction time false alarm rate1.21.74.50.3-0.41.4-1.2-1.21.2-1.4-0.42.11.81.0-1.1-1.9
Reaction time premature initiation rate0.40.51.1-0.7-1.0-0.50.30.3-0.30.6-1.00.1-0.51.1-1.1-1.0
Reaction time premature initiations0.10.20.4-0.5-0.5-0.50.40.3-0.30.6-0.5-0.2-0.70.5-0.5-0.3
Std. dev. reaction times1.22.36.9-1.5-2.0-0.30.20.2-0.20.3-2.00.8-0.22.3-2.4-2.6
Reaction time trials completed0.20.41.20.50.80.1-0.1-0.30.3-0.10.8-0.3-0.3-0.91.01.1
Reaction time trials AUC0.20.41.10.60.80.3-0.2-0.50.5-0.30.9-0.1-0.1-1.01.01.0
Run reversals in cocaine runway, females0.40.40.8-0.8-0.8-0.50.40.5-0.50.4-0.9-0.3-0.30.9-0.9-0.9
Run reversals in cocaine runway, males1.31.32.40.50.11.3-1.4-1.51.5-1.40.11.31.50.4-0.5-1.2
Latency to leave start box in cocaine runway1.21.42.31.41.51.0-1.1-1.21.2-1.11.40.30.9-1.41.31.0
Latency to leave start box in cocaine runway, F2.22.54.01.82.01.3-1.5-1.51.5-1.41.90.51.2-1.81.81.4
Latency to leave start box in cocaine runway, M0.40.30.8-0.6-0.8-0.20.20.1-0.10.2-0.80.2-0.20.9-0.9-0.9
Std. dev. time between licks in bursts2.22.94.2-1.9-1.8-1.81.91.9-1.91.9-1.7-1.1-2.01.5-1.4-0.8
Total sessions with >9 infusions0.10.10.3-0.4-0.5-0.10.10.1-0.10.1-0.50.0-0.10.5-0.5-0.5
Short access day 1 total inactive lever presses1.41.92.71.51.41.6-1.5-1.61.6-1.51.31.41.4-1.11.00.5
Short access day 10 total inactive lever presses0.10.20.40.40.30.6-0.5-0.50.5-0.60.30.60.4-0.10.1-0.1
Short access day 1 total infusions0.00.00.10.20.20.1-0.1-0.10.1-0.10.20.00.1-0.20.20.2
Short access day 10 total infusions0.50.61.40.91.10.4-0.4-0.30.3-0.41.10.00.4-1.21.21.1
Short access total infusions0.00.00.1-0.2-0.1-0.20.20.2-0.20.2-0.2-0.2-0.20.1-0.1-0.1
ShA early post infusion interval2.01.94.11.20.81.8-1.6-1.61.6-1.80.92.01.7-0.50.4-0.4
ShA late post infusion interval7.57.511.13.02.43.3-3.3-3.13.1-3.32.43.23.0-1.81.70.4
ShA early loading1.81.84.31.51.90.6-0.6-0.60.6-0.61.9-0.40.5-2.02.12.1
ShA late loading1.41.94.0-1.4-1.1-1.81.61.7-1.71.6-1.0-2.0-1.40.7-0.60.0
Short access day 1 locomotion0.60.81.70.60.21.1-1.1-1.11.1-1.10.21.31.20.1-0.2-0.7
Short access day 10 total locomotion0.30.61.10.80.70.9-0.9-0.70.7-0.90.70.81.0-0.60.50.2
Short access total locomotion0.00.00.1-0.1-0.0-0.20.20.2-0.20.2-0.0-0.3-0.1-0.00.10.1
ShA early average infusions0.30.40.70.80.90.4-0.5-0.30.3-0.50.8-0.20.5-0.80.80.7
ShA late average infusions3.63.85.8-2.0-1.6-2.42.42.3-2.32.3-1.6-2.4-2.01.1-1.0-0.1
ShA early timeout0.20.20.50.60.50.4-0.5-0.50.5-0.50.50.10.7-0.50.50.3
ShA late timeout1.31.52.5-1.5-1.6-1.11.20.9-0.91.1-1.5-0.6-0.91.4-1.4-1.1
ShA early titration0.60.61.40.91.20.3-0.5-0.20.2-0.41.1-0.60.5-1.11.21.1
ShA late titration6.46.810.0-2.8-2.3-3.23.23.0-3.03.1-2.3-3.0-2.81.6-1.5-0.3
ShA total infusions1.72.02.9-1.5-1.3-1.71.71.7-1.71.6-1.3-1.7-1.41.0-0.9-0.2
One hour access (0.3 mA shock)0.10.20.3-0.4-0.3-0.50.30.3-0.30.4-0.5-0.3-0.50.4-0.4-0.3
Shock compulsivity1.83.44.4-2.1-2.0-2.01.81.9-1.91.9-2.1-1.5-1.61.8-1.8-1.2
Compulsive drug intake0.40.51.1-0.5-0.2-0.90.90.7-0.70.9-0.2-1.1-0.9-0.10.20.6
One hour access (shock baseline)0.50.81.50.90.61.1-1.2-1.01.0-1.10.51.21.1-0.20.2-0.3
Social response proportion0.30.40.6-0.7-0.8-0.50.40.5-0.50.5-0.7-0.3-0.60.7-0.7-0.7
Social responses1.41.82.5-1.4-1.4-1.41.51.4-1.41.4-1.4-1.1-1.61.2-1.2-0.8
Social time0.00.10.2-0.1-0.20.2-0.1-0.10.1-0.2-0.20.30.20.3-0.3-0.5
Soleus weight2.47.011.52.82.33.2-3.1-3.43.4-3.12.23.12.6-1.71.50.3
Bone: stiffness0.10.10.2-0.2-0.4-0.10.10.3-0.30.1-0.40.2-0.20.4-0.4-0.4
Tibialis anterior weight4.515.220.04.54.44.0-4.0-4.44.4-3.84.22.93.5-3.93.72.6
Time to tail flick, vehicle, before self-admin2.32.33.61.81.91.5-1.6-1.51.5-1.51.70.91.6-1.61.51.0
Time to tail flick, vehicle, after self-admin0.81.11.81.21.30.8-0.8-0.80.8-0.81.40.20.8-1.31.31.1
Time to tail flick, test, before self-admin5.35.49.92.73.11.7-1.8-1.81.8-1.83.00.41.7-3.03.02.6
Time to tail flick, test, after self-admin1.51.62.41.51.41.3-1.1-1.01.0-1.21.61.01.0-1.51.41.1
Delta time to tail flick, vehicle, before/after SA0.00.00.10.20.20.1-0.1-0.10.1-0.10.3-0.20.0-0.30.30.3
Delta time to tail flick, test, before/after SA0.90.92.1-1.0-1.4-0.30.40.5-0.50.4-1.30.4-0.41.4-1.4-1.4
Tibia length0.10.20.40.50.30.5-0.6-0.10.1-0.50.40.40.6-0.20.20.0
Ambulatory time before self-admin0.10.10.20.30.40.2-0.2-0.20.2-0.30.5-0.20.2-0.50.50.4
Ambulatory time after self-admin0.50.60.90.90.80.8-0.8-0.90.9-0.90.90.40.7-0.80.80.5
Bone: tissue strength1.21.31.9-1.3-1.4-1.11.00.9-0.91.0-1.4-0.6-0.81.3-1.3-1.1
Total heroin consumption0.30.30.6-0.6-0.5-0.60.70.6-0.60.6-0.4-0.7-0.80.3-0.3-0.1
Total infusions2.83.66.0-1.9-1.6-2.32.32.5-2.52.3-1.6-2.0-2.01.1-1.0-0.1
Bone: trabecular number0.71.22.9-1.1-0.9-1.21.21.3-1.31.2-0.9-1.0-1.70.7-0.7-0.2
Bone: trabecular spacing1.41.82.91.51.41.5-1.4-1.41.4-1.41.41.21.7-1.21.20.7
Bone: trabecular thickness0.81.01.3-1.2-1.1-1.00.90.9-0.90.9-1.1-0.7-1.11.1-1.0-0.8
Bone: trabecular tissue density0.20.31.00.10.4-0.30.40.2-0.20.40.4-0.7-0.5-0.60.71.0
Water consumed over 24 hours0.60.82.40.1-0.40.9-0.9-0.80.8-0.9-0.41.60.80.8-0.9-1.5
Number of responses in last shaping day1.82.03.61.30.91.7-1.7-1.91.9-1.70.91.91.6-0.50.4-0.3