Osbpl7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr10_82532613_82533242 0.21 0.11 0.0e+00 0.19 0.2 0.19 0.19 1.7e-17 2.6e-18 8.8e-18 2.3e-17
2 BLA intron excision ratio chr10_82533355_82533845 0.16 0.09 6.5e-07 0.11 0.1 0.08 0.12 2.4e-06 4.4e-06 3.2e-05 1.2e-06
3 Adipose gene expression Osbpl7 0.02 0.02 2.3e-03 0.01 0.01 0 0.01 3.9e-02 1.5e-02 1.7e-01 3.5e-02
4 IC intron excision ratio chr10_82532613_82533242 0.22 0.13 4.0e-07 0.16 0.14 0.13 0.15 2.3e-07 1.3e-06 3.7e-06 6.8e-07
5 PL intron excision ratio chr10_82532613_82533242 0.16 0.08 0.0e+00 0.17 0.18 0.17 0.18 2.4e-18 5.2e-19 2.1e-18 4.9e-19
6 BLA intron excision ratio chr10_82532613_82533242 0.16 0.08 1.2e-10 0.18 0.2 0.19 0.19 6.6e-10 1.1e-10 2.0e-10 1.5e-10
7 NAcc gene expression Osbpl7 0.1 0.05 0.0e+00 0.13 0.15 0.14 0.14 2.5e-19 1.7e-21 9.7e-21 2.7e-21
8 Adipose intron excision ratio chr10_82532613_82533845 0.04 0.03 1.8e-05 0.04 0.04 0.04 0.04 2.8e-05 2.3e-05 8.1e-05 5.4e-05
9 BLA gene expression Osbpl7 0.09 0.07 3.5e-03 0.05 0.04 0.05 0.05 1.1e-03 3.1e-03 1.6e-03 1.8e-03
10 pVTA gene expression Osbpl7 0.09 0.06 6.8e-06 0.07 0.07 0.08 0.07 4.3e-06 4.8e-06 5.3e-07 3.1e-06
11 PL gene expression Osbpl7 0.05 0.03 1.7e-07 0.06 0.07 0.06 0.07 1.2e-07 8.9e-08 1.3e-07 8.5e-08
12 PL intron excision ratio chr10_82532613_82533845 0.13 0.08 4.6e-14 0.13 0.13 0.13 0.14 3.1e-14 4.3e-14 1.3e-13 7.0e-15
13 Brain intron excision ratio chr10_82532613_82533845 0.1 0.06 4.6e-13 0.14 0.13 0.13 0.14 2.2e-13 2.1e-12 8.8e-12 5.1e-13
14 NAcc intron excision ratio chr10_82532613_82533845 0.09 0.04 0.0e+00 0.13 0.13 0.13 0.13 1.7e-19 2.5e-19 3.1e-19 3.2e-19
15 IC gene expression Osbpl7 0.13 0.09 5.9e-05 0.11 0.09 0.1 0.09 2.0e-05 1.0e-04 7.6e-05 1.0e-04
16 BLA intron excision ratio chr10_82532613_82533845 0.22 0.12 5.5e-10 0.17 0.17 0.16 0.19 1.6e-09 3.4e-09 9.9e-09 3.2e-10
17 Brain intron excision ratio chr10_82533355_82533845 0.17 0.1 0.0e+00 0.18 0.18 0.17 0.18 2.1e-16 2.1e-16 1.6e-15 6.8e-17
18 pVTA intron excision ratio chr10_82532613_82533845 0.1 0.06 2.9e-09 0.12 0.11 0.11 0.11 1.3e-09 2.4e-09 3.5e-09 3.4e-09
19 Adipose alternative TSS NM_001107044.1 0.02 0.01 1.4e-03 0.03 0.02 0.02 0.02 4.8e-04 2.5e-03 3.1e-03 1.9e-03
20 Adipose alternative TSS XM_006247300.5 0.02 0.01 9.5e-03 0.03 0.01 0.02 0.02 2.5e-04 3.8e-02 5.4e-03 1.1e-03
21 IC intron excision ratio chr10_82532613_82533845 0.12 0.08 8.3e-05 0.14 0.1 0.16 0.12 1.2e-06 9.0e-05 3.4e-07 1.6e-05
22 PL intron excision ratio chr10_82533355_82533845 0.17 0.12 6.7e-12 0.11 0.11 0.13 0.12 2.2e-12 3.7e-12 1.2e-13 4.2e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.83.14.8-1.2-1.7-1.4-1.6-1.8-1.9-1.92.0-1.70.6-1.91.91.91.8-1.71.8-2.21.8-1.81.82.0-1.4
Area under the delay curve0.40.51.91.30.61.20.60.70.70.7-0.50.9-1.40.6-0.6-0.5-0.40.8-0.40.0-0.30.1-0.10.20.2
BMI with tail11.941.154.5-7.4-7.2-7.2-6.9-6.9-6.4-6.45.9-6.52.6-6.86.66.66.7-6.46.9-5.46.7-6.76.75.0-5.7
BMI without tail0.51.43.3-1.7-1.8-1.4-1.4-1.3-0.9-0.90.7-1.0-0.7-1.41.21.21.3-1.01.3-0.51.2-1.11.1-0.3-1.7
Body weight0.94.014.0-2.9-2.3-2.1-2.2-2.1-0.8-0.80.3-1.5-3.7-2.21.91.92.1-1.51.80.01.8-1.51.5-0.7-3.5
Weight adjusted by age0.60.91.90.80.80.90.80.81.01.0-1.00.8-0.30.8-1.0-1.1-0.91.0-1.10.9-1.01.2-1.2-1.41.0
Bone surface0.50.91.3-1.0-0.9-0.9-0.8-0.9-0.9-0.90.8-0.90.2-1.11.11.11.1-1.01.0-0.91.0-1.01.00.8-0.9
Bone volume1.52.73.6-1.6-1.7-1.6-1.6-1.7-1.6-1.61.6-1.60.5-1.81.91.91.8-1.71.7-1.71.7-1.71.71.4-1.5
Breakpoint value in progressive ratio session3.13.75.91.62.01.82.22.12.22.1-2.32.0-1.52.1-1.9-2.1-2.21.9-1.72.4-1.51.6-1.6-2.01.1
Number of licking bursts0.10.10.40.50.30.30.30.40.10.2-0.10.40.50.4-0.3-0.2-0.40.5-0.40.0-0.50.4-0.40.10.6
Context. condit. distance diff. score0.20.30.5-0.7-0.4-0.6-0.5-0.6-0.4-0.50.4-0.70.7-0.50.60.60.5-0.60.6-0.30.6-0.60.60.4-0.5
Locomotion velocity, session 10.30.41.2-1.1-0.7-0.9-0.7-0.8-0.6-0.60.4-0.40.1-0.60.70.50.7-0.40.6-0.20.6-0.60.60.2-0.6
Locomotion distance, session 12.73.45.51.31.61.61.71.62.12.1-2.22.1-2.11.6-1.6-1.6-1.62.1-1.82.3-1.81.9-1.9-2.30.7
Locomotion velocity, session 21.01.22.00.81.01.01.10.91.21.2-1.21.3-1.40.9-0.9-1.0-0.91.3-1.11.2-1.11.1-1.1-1.10.5
Locomotion distance, session 23.54.87.02.02.02.22.12.02.42.4-2.42.6-2.42.0-2.0-2.0-2.02.6-2.22.3-2.22.3-2.3-2.31.2
Locomotion velocity, session 30.10.10.40.1-0.00.2-0.00.10.30.3-0.3-0.1-0.70.1-0.2-0.1-0.10.0-0.10.3-0.10.2-0.2-0.6-0.2
Locomotion distance, session 33.03.34.01.71.81.91.71.72.02.0-1.91.9-1.81.7-1.8-1.7-1.72.0-1.81.8-1.81.9-1.9-1.81.1
Stereotopy head waving bouts, day 34.35.17.0-1.7-2.3-1.9-2.3-2.2-2.5-2.52.6-2.31.4-2.22.32.22.2-2.42.3-2.62.3-2.42.42.4-1.8
Stereotopy head waving duration, day 33.23.94.9-1.8-2.1-1.9-2.1-2.0-2.1-2.12.1-2.01.1-1.92.02.01.9-2.22.1-2.02.0-2.02.01.8-1.7
Locomotion velocity, session 71.71.82.51.21.31.31.31.31.41.4-1.41.6-0.21.3-1.4-1.4-1.31.5-1.41.4-1.41.4-1.4-1.61.2
Locomotion distance, session 75.26.58.02.72.72.82.62.62.72.7-2.52.7-1.22.6-2.6-2.6-2.62.8-2.72.4-2.72.7-2.7-2.32.2
Stereotopy head waving bouts, day 70.50.61.1-0.5-0.7-0.6-0.6-0.7-0.8-0.90.9-0.90.9-0.70.70.70.7-1.00.8-0.90.8-0.80.80.6-0.7
Stereotopy head waving duration, day 70.40.50.7-0.6-0.6-0.7-0.6-0.6-0.7-0.70.7-0.80.8-0.60.60.70.7-0.90.7-0.60.7-0.70.70.4-0.7
Locomotion velocity, session 80.10.20.9-1.0-0.0-0.6-0.0-0.30.20.1-0.5-0.1-0.7-0.30.30.30.30.10.10.70.1-0.10.1-0.7-0.5
Locomotion distance, session 80.81.22.20.71.00.91.10.91.31.3-1.41.2-1.10.9-0.8-0.8-0.81.4-1.11.4-1.11.1-1.1-1.50.3
Degree of sensitization distance0.10.10.20.10.20.10.20.30.20.2-0.30.30.20.4-0.3-0.4-0.30.4-0.30.4-0.30.3-0.3-0.40.4
Degree of sensitization stereotypy0.10.10.70.40.10.20.20.2-0.1-0.10.2-0.00.80.2-0.2-0.2-0.2-0.1-0.0-0.2-0.1-0.00.00.00.2
Conditioned locomotion1.01.11.8-0.8-1.1-0.8-1.1-1.0-1.0-1.01.1-1.2-0.2-1.21.21.21.2-1.31.1-1.21.1-1.01.01.0-1.2
Cocaine response after cond. corrected5.46.58.5-2.0-2.6-2.1-2.5-2.6-2.5-2.52.7-2.80.6-2.62.72.72.6-2.92.7-2.82.7-2.72.72.8-2.3
Cocaine response after cond. not corrected3.03.55.3-1.1-1.8-1.2-1.8-1.9-1.8-1.82.1-2.2-0.1-1.92.01.91.8-2.32.0-2.22.0-2.02.02.2-1.9
Cocaine response before conditioning2.42.94.82.21.92.11.81.71.81.7-1.51.6-1.11.8-1.7-1.8-1.81.6-1.81.2-1.81.8-1.8-1.31.2
Saline control response0.60.91.21.11.01.11.11.01.01.0-0.90.8-0.30.9-0.9-1.0-0.90.7-1.00.6-1.01.0-1.0-0.61.1
Bone: connectivity density0.30.51.4-0.0-0.4-0.2-0.3-0.5-0.7-0.80.9-0.80.5-0.60.70.70.6-0.70.6-1.20.6-0.70.71.2-0.3
Bone: cortical apparent density5.57.511.53.43.23.13.23.12.52.5-2.32.30.43.1-3.0-2.9-3.12.4-2.92.1-2.82.7-2.7-1.63.1
Bone: cortical area0.10.10.90.0-0.20.0-0.1-0.3-0.2-0.20.3-0.0-0.9-0.40.40.40.5-0.10.2-0.50.3-0.20.20.4-0.4
Bone: cortical porosity0.50.51.5-0.3-0.6-0.5-0.8-0.7-0.8-0.70.9-0.80.6-0.70.60.70.7-0.90.7-1.10.7-0.70.71.2-0.3
Bone: cortical porosity0.60.71.7-0.4-0.7-0.5-0.9-0.8-0.9-0.81.0-0.90.2-0.80.80.80.8-0.90.8-1.30.8-0.80.81.3-0.5
Bone: cortical thickness0.50.82.11.40.91.31.00.80.80.9-0.60.9-1.20.7-0.8-0.7-0.70.9-0.90.2-0.90.9-0.9-0.30.6
Bone: cortical thickness0.80.93.61.91.11.61.10.90.90.9-0.40.7-1.20.8-0.9-0.8-0.80.6-0.9-0.1-0.90.9-0.90.10.7
Bone: cortical tissue density5.98.012.23.53.33.23.43.32.62.6-2.42.40.33.2-3.1-3.0-3.22.4-3.02.2-2.92.8-2.8-1.73.2
Condit. Reinf. active minus inactive responses0.10.10.30.50.50.40.50.50.30.2-0.20.40.40.4-0.3-0.4-0.40.3-0.40.1-0.30.3-0.30.20.4
Condit. Reinf. active-inactive response ratio0.30.30.7-0.2-0.5-0.4-0.5-0.4-0.6-0.60.7-0.50.8-0.30.40.30.3-0.60.5-0.70.5-0.60.60.8-0.2
Condit. Reinf. active responses0.10.10.50.30.50.20.40.30.10.0-0.00.20.70.2-0.2-0.3-0.20.2-0.2-0.1-0.20.1-0.10.50.4
Condit. Reinf. inactive responses0.10.10.50.50.70.40.60.30.30.3-0.20.30.20.3-0.3-0.4-0.30.4-0.30.1-0.30.2-0.20.20.6
Incentive salience index mean0.30.40.80.90.70.70.60.70.40.4-0.30.70.60.7-0.6-0.7-0.60.6-0.60.2-0.60.5-0.50.10.8
Condit. Reinf. lever presses0.81.12.61.31.01.11.01.10.70.8-0.61.11.11.2-1.3-1.3-1.11.0-1.10.6-1.11.0-1.0-0.31.6
Condit. Reinf. active minus inactive responses0.10.10.30.1-0.5-0.0-0.4-0.3-0.3-0.20.50.10.4-0.20.10.10.20.10.2-0.50.1-0.10.10.4-0.0
Condit. Reinf. active-inactive response ratio0.40.52.1-0.5-0.8-0.6-0.8-0.6-0.7-0.70.8-0.81.5-0.60.50.50.6-0.80.7-0.70.6-0.60.60.7-0.2
Condit. Reinf. active responses0.10.10.30.5-0.00.3-0.00.1-0.00.00.20.40.40.1-0.2-0.3-0.10.4-0.1-0.4-0.20.2-0.20.40.4
Condit. Reinf. inactive responses0.50.61.51.20.81.00.70.70.50.5-0.31.0-0.00.7-0.8-0.9-0.71.1-0.8-0.0-0.90.8-0.80.11.0
Condit. Reinf. lever presses0.60.91.21.00.80.90.80.90.90.9-0.81.1-0.00.9-1.1-1.1-0.91.0-1.00.6-1.11.1-1.1-0.71.1
Condit. Reinf. lever reinforcers received0.20.20.70.80.30.60.30.40.30.3-0.10.70.20.4-0.5-0.6-0.40.7-0.5-0.1-0.50.5-0.50.10.7
Conditioned reinforcement - actives0.40.71.4-0.4-1.1-0.6-1.0-0.9-1.0-0.91.2-0.90.3-0.90.80.80.8-0.90.8-1.20.8-0.50.50.5-0.5
Conditioned reinforcement - inactives0.30.41.00.70.10.60.40.60.40.5-0.40.50.40.6-0.7-0.6-0.60.6-0.80.4-0.71.0-1.0-1.00.9
Conditioned locomotion3.85.07.6-1.8-2.5-2.1-2.6-2.3-2.5-2.42.6-2.31.4-2.32.22.32.3-2.22.2-2.72.4-1.91.92.3-1.2
Patch foraging indifference point 0 sec0.91.73.4-0.7-1.3-0.9-1.3-1.3-1.3-1.31.5-1.3-0.0-1.31.31.21.3-1.41.3-1.91.3-1.31.31.8-0.9
Patch foraging indifference point AUC0.20.20.60.20.40.20.40.50.40.4-0.60.60.70.5-0.4-0.4-0.50.3-0.50.6-0.50.5-0.5-0.80.5
Delay disc. indifference point, 0s delay1.31.53.51.91.41.61.41.41.21.2-1.01.5-0.91.3-1.5-1.4-1.21.4-1.00.5-1.00.7-0.7-0.21.2
Delay disc. indifference point, 16s delay0.40.51.0-0.2-0.7-0.3-0.6-0.6-0.5-0.60.7-0.5-0.6-0.70.80.90.8-0.50.6-0.90.7-0.70.70.8-1.0
Delay disc. indifference point, 2s delay0.40.51.91.40.31.10.20.60.60.7-0.30.9-1.10.6-0.8-0.7-0.50.7-0.6-0.1-0.60.5-0.50.10.9
Delay disc. indifference point, 24s delay0.20.31.80.50.70.60.60.40.60.5-0.50.4-1.30.4-0.3-0.2-0.30.4-0.30.5-0.20.0-0.0-0.1-0.7
Delay disc. indifference point, 4s delay3.94.18.02.72.12.62.12.12.32.3-2.02.1-2.82.0-2.1-2.0-1.92.0-1.71.4-1.71.5-1.5-1.41.2
Delay disc. indifference point, 8s delay0.10.10.60.60.20.50.20.20.10.10.00.2-0.70.1-0.00.0-0.00.20.3-0.30.2-0.50.50.8-0.2
Indifference point function ln k0.10.22.30.00.20.0-0.1-0.2-0.1-0.10.2-0.3-1.5-0.30.20.20.2-0.10.2-0.30.2-0.20.20.4-0.7
Indifference point function log k0.10.22.30.00.20.0-0.1-0.2-0.1-0.10.2-0.3-1.5-0.30.20.20.2-0.10.2-0.30.2-0.20.20.4-0.7
Patch foraging total patch changes 0 sec0.81.52.9-0.7-1.2-0.9-1.2-1.2-1.2-1.21.4-1.3-0.3-1.31.21.21.3-1.41.3-1.71.3-1.21.21.6-1.0
Patch foraging total patch changes 12 sec0.40.62.80.1-0.3-0.2-0.3-0.4-0.7-0.70.9-0.81.1-0.50.60.50.5-0.90.6-1.40.6-0.70.71.70.2
Patch foraging total patch changes 18 sec1.11.72.2-1.3-1.4-1.4-1.4-1.2-1.4-1.31.3-1.31.5-1.31.21.31.3-1.51.3-1.41.2-1.21.21.3-0.4
Patch foraging total patch changes 24 sec0.81.52.6-0.8-1.6-1.0-1.2-1.1-1.2-1.21.3-1.41.2-1.01.11.11.1-1.61.3-1.51.2-1.21.21.2-0.8
Patch foraging total patch changes 6 sec0.81.22.5-0.8-1.0-0.9-1.1-1.1-1.1-1.11.2-1.01.1-1.01.11.01.1-1.21.1-1.31.1-1.11.11.6-0.5
Patch foraging time to switch 0 sec0.10.20.8-0.3-0.3-0.4-0.2-0.3-0.5-0.40.5-0.50.9-0.40.40.40.4-0.30.4-0.50.4-0.40.40.80.0
Patch foraging water rate 0 sec0.51.02.2-0.8-1.1-0.8-1.1-1.1-0.8-0.80.8-1.0-1.0-1.01.11.11.0-1.11.0-0.91.0-0.90.90.2-1.5
Patch foraging water rate 12 sec0.20.42.50.50.40.60.30.40.70.8-0.70.3-1.60.6-0.6-0.5-0.60.2-0.50.8-0.40.5-0.5-0.7-0.2
Patch foraging water rate 18 sec0.61.02.51.60.61.40.81.11.01.1-0.80.6-0.91.1-1.2-1.2-1.10.5-1.00.5-1.01.1-1.1-0.90.5
Patch foraging water rate 24 sec0.40.51.1-0.4-0.7-0.5-0.8-0.8-0.7-0.70.8-0.9-0.5-0.70.70.70.7-1.00.7-1.00.8-0.70.70.6-0.8
Patch foraging water rate 6 sec0.10.20.50.70.20.50.40.40.30.3-0.10.2-0.50.4-0.5-0.4-0.40.1-0.40.0-0.40.4-0.4-0.50.4
Seeking ratio, delayed vs. immediate footshock0.30.41.2-1.0-0.2-0.8-0.2-0.7-0.6-0.70.5-1.10.0-0.70.90.80.6-0.80.3-0.30.4-0.10.10.2-0.4
Distance traveled before self-admin0.00.10.30.2-0.10.20.20.20.20.3-0.20.4-0.50.2-0.2-0.2-0.10.20.20.10.1-0.30.30.4-0.1
Distance traveled after self-admin1.11.42.7-1.2-1.0-1.0-1.2-1.1-0.8-0.90.8-1.2-0.8-1.11.21.01.2-1.31.4-0.71.4-1.61.60.9-1.6
Extensor digitorum longus weight0.20.93.8-1.9-0.7-1.1-0.6-0.50.40.4-1.0-0.2-1.9-0.50.40.40.50.00.31.60.3-0.10.1-2.0-1.6
Bone: elastic displacement0.30.30.8-0.6-0.7-0.6-0.6-0.5-0.6-0.60.6-0.20.9-0.50.50.60.5-0.20.6-0.60.5-0.60.60.7-0.3
Bone: elastic work0.00.00.2-0.0-0.1-0.0-0.1-0.2-0.0-0.00.10.3-0.5-0.20.30.30.20.20.1-0.30.1-0.10.10.2-0.4
Bone: endosteal estimation0.41.02.3-1.5-1.0-1.2-0.9-1.0-0.7-0.80.5-0.9-0.6-1.11.11.11.1-1.01.0-0.41.1-1.01.00.4-1.3
Bone: endosteal perimeter0.71.43.5-1.9-1.3-1.6-1.3-1.3-1.1-1.10.8-1.00.0-1.21.31.31.3-1.11.3-0.61.3-1.21.20.7-1.2
Epididymis fat weight0.20.61.2-0.9-0.7-0.8-1.0-0.9-0.7-0.70.7-0.4-0.4-0.90.80.70.8-0.40.8-0.60.8-0.70.70.7-1.1
Delta time in closed arm before/after self-admin0.20.10.7-0.60.2-0.3-0.0-0.10.20.2-0.4-0.2-0.9-0.10.1-0.00.0-0.10.30.70.1-0.50.5-0.1-0.8
Delta time in open arm before/after self-admin1.81.74.51.31.21.31.31.41.31.3-1.21.40.41.4-1.4-1.3-1.31.2-1.31.1-1.31.4-1.4-1.12.1
Diff in mean of infusions in LGA sessions0.60.71.70.70.90.71.20.90.80.8-0.90.50.01.0-1.0-1.3-1.10.5-0.51.0-0.00.6-0.6-0.51.0
Delay discount exponential model param0.60.62.6-1.3-0.7-1.3-0.7-0.8-0.9-0.90.6-1.01.6-0.70.70.60.5-0.90.5-0.20.4-0.20.2-0.0-0.2
Extinction: sum of active levers before priming0.50.61.90.60.70.70.70.60.90.8-0.90.5-1.30.6-0.6-0.6-0.70.4-0.41.0-0.30.5-0.5-1.4-0.7
Active lever presses in extinction session 60.20.21.1-0.50.0-0.4-0.4-0.3-0.4-0.40.3-0.00.4-0.40.60.40.2-0.20.3-0.00.5-0.40.40.3-1.0
Bone: final force0.30.51.5-0.1-0.6-0.2-0.5-0.6-0.7-0.70.9-0.6-0.4-0.80.70.80.8-0.80.6-1.20.7-0.60.61.0-0.6
Bone: final moment0.40.61.7-0.1-0.6-0.2-0.5-0.7-0.7-0.70.9-0.7-0.8-0.80.80.80.8-0.90.7-1.30.7-0.70.71.1-0.7
Food consumed during 24 hour testing period1.01.42.70.81.31.01.31.21.41.3-1.51.0-1.11.2-1.2-1.2-1.20.8-1.21.6-1.11.2-1.2-1.40.5
Glucose0.91.53.7-0.6-1.4-0.7-1.5-1.3-1.0-1.01.2-0.8-1.8-1.41.21.31.4-0.81.2-1.51.1-1.01.00.6-1.9
Heart weight1.21.94.0-2.0-1.9-1.7-1.6-1.3-1.1-1.10.8-1.20.4-1.51.61.61.5-1.41.4-0.61.4-1.31.30.3-1.7
Delay discount hyperbolic model param0.60.73.0-1.4-0.7-1.3-0.7-0.8-0.9-0.90.7-1.01.7-0.70.80.60.5-0.90.5-0.20.5-0.20.20.0-0.2
Intermittent access intake day 1-15 change0.40.91.8-1.1-1.2-1.2-1.3-1.1-1.1-1.11.0-0.90.7-1.01.01.11.1-0.80.9-0.90.8-0.60.6-0.2-0.7
Intermittent access intake escalation0.30.71.3-1.0-1.0-1.0-1.1-0.9-0.9-0.90.9-0.70.9-0.80.80.90.9-0.70.7-0.70.6-0.40.4-0.3-0.4
Intermittent access intake escalation 21.61.93.3-1.8-1.7-1.8-1.6-1.5-1.5-1.51.3-1.41.0-1.41.41.51.5-1.31.3-1.01.2-1.01.0-0.1-1.1
Intermitt. access day 1 inactive lever presses0.31.02.51.10.70.90.50.80.60.7-0.51.00.60.9-1.0-0.9-0.91.2-1.30.5-1.01.6-1.6-1.31.5
Intermitt. access day 15 inactive lever presses0.51.13.1-0.9-1.1-1.0-1.2-1.0-1.2-1.21.2-1.21.8-0.90.91.00.9-1.10.9-1.11.1-0.80.80.9-0.1
Intermitt. access escalation Index0.71.01.9-1.0-0.5-0.8-0.6-1.0-0.5-0.50.4-1.3-1.1-1.01.11.01.0-1.21.1-0.61.3-1.31.31.4-0.9
Intermittent access day 1 total infusions0.00.10.20.40.20.40.40.30.30.3-0.20.2-0.40.1-0.3-0.2-0.20.2-0.20.1-0.1-0.00.0-0.1-0.4
Intermittent access day 15 total infusions0.00.10.2-0.2-0.3-0.2-0.2-0.2-0.2-0.20.2-0.20.3-0.20.10.30.3-0.20.2-0.10.2-0.30.3-0.4-0.4
Intermittent access terminal intake (last 3 days)0.30.41.0-0.6-0.6-0.7-0.5-0.6-0.7-0.70.6-0.61.0-0.60.50.60.6-0.60.6-0.50.6-0.90.90.3-0.6
Intermittent access total infusions0.00.00.4-0.0-0.1-0.00.0-0.1-0.0-0.00.0-0.1-0.2-0.1-0.00.10.1-0.20.10.10.2-0.30.3-0.3-0.7
Intermittent access day 1 locomotion0.10.10.30.50.30.50.30.30.30.3-0.10.2-0.10.3-0.3-0.3-0.30.2-0.3-0.0-0.10.2-0.2-0.00.3
Intermittent access day 15 total locomotion0.20.30.7-0.3-0.6-0.4-0.7-0.6-0.7-0.70.8-0.60.2-0.60.60.70.6-0.50.6-0.80.8-0.40.40.1-0.7
Intermittent access total locomotion0.60.71.4-0.4-0.8-0.6-0.9-0.8-0.9-0.91.1-0.80.6-0.80.80.80.8-0.70.8-1.21.0-0.80.81.0-0.6
Intermittent access standard deviation0.91.92.4-1.3-1.5-1.4-1.5-1.4-1.4-1.41.4-1.50.9-1.41.41.51.4-1.51.5-1.41.5-1.41.40.7-1.3
Left kidney weight0.20.912.7-0.4-0.10.1-0.2-0.20.60.5-0.70.1-3.6-0.30.30.30.20.00.00.60.10.1-0.1-1.1-1.7
Right kidney weight0.31.34.0-1.0-1.4-0.8-1.3-1.2-0.7-0.70.7-0.9-2.0-1.31.11.21.3-1.01.1-0.91.1-0.90.90.3-1.9
Cocaine induced anxiety0.20.21.0-1.0-0.3-0.7-0.4-0.4-0.1-0.1-0.2-0.4-0.2-0.50.40.50.5-0.30.60.40.4-0.40.4-0.6-0.8
Post-drug Anxiety0.00.00.2-0.30.2-0.20.20.20.10.1-0.30.10.40.1-0.2-0.1-0.10.20.10.4-0.00.0-0.0-0.20.4
Baseline Anxiety0.70.82.01.30.71.00.91.00.50.5-0.31.00.61.0-1.0-1.0-1.01.0-0.90.2-0.80.8-0.80.21.4
Tail length12.448.459.06.76.97.36.96.97.77.6-7.56.8-7.36.8-6.7-6.8-6.76.7-7.07.2-6.97.2-7.2-7.63.6
Length with tail5.423.349.23.84.54.64.44.45.65.5-5.74.7-7.04.3-4.3-4.3-4.14.6-4.75.5-4.64.9-4.9-5.91.6
Length without tail0.20.75.1-1.3-0.4-0.8-0.7-0.80.00.0-0.3-0.3-2.3-0.80.70.70.9-0.40.50.30.5-0.30.3-0.3-1.4
Times rat made contact with spout0.00.00.10.40.30.30.30.30.10.10.0-0.0-0.20.2-0.1-0.1-0.20.1-0.2-0.0-0.10.1-0.10.20.1
Lifetime Intake0.00.00.10.0-0.10.00.0-0.0-0.0-0.00.0-0.20.0-0.0-0.10.00.1-0.20.00.00.2-0.20.2-0.2-0.4
Liver weight, left0.10.10.70.10.10.20.20.30.40.3-0.40.50.00.4-0.3-0.3-0.40.5-0.30.6-0.30.3-0.3-0.8-0.2
Liver weight, right0.10.21.80.60.40.60.30.10.40.3-0.20.1-1.30.1-0.0-0.0-0.10.1-0.10.0-0.00.1-0.1-0.2-1.3
Locomotor activity0.71.12.1-0.8-0.8-0.9-0.7-0.9-1.1-1.11.1-1.50.8-1.01.01.01.0-1.41.1-1.11.2-1.21.21.1-0.7
Locomotor testing distance1.52.74.3-1.0-1.4-1.3-1.2-1.4-1.8-1.82.0-2.01.7-1.41.41.51.4-2.01.7-2.01.7-1.81.82.1-0.6
Locomotor testing rearing0.10.21.50.60.00.30.20.1-0.4-0.40.6-0.51.20.1-0.1-0.0-0.1-0.50.2-0.70.2-0.30.30.80.3
Locomotion in novel chamber0.50.72.11.51.11.30.80.80.80.8-0.50.8-0.80.9-0.8-1.0-1.00.9-0.30.4-0.70.2-0.20.40.2
Locomotion in novel chamber post-restriction1.01.63.7-1.2-1.3-1.4-1.4-1.2-1.4-1.31.3-0.91.9-1.11.21.11.0-0.81.3-1.31.4-1.21.21.6-0.3
Fecal boli incidents, locomotor time 12.33.44.6-2.2-2.0-2.1-2.1-1.9-1.9-1.91.7-1.81.3-1.92.02.01.9-1.81.8-1.51.9-1.71.71.3-1.6
Change in fecal boli incidents, locomotor task2.22.23.41.81.61.81.61.61.51.5-1.41.6-1.01.5-1.7-1.6-1.51.7-1.41.2-1.61.3-1.3-1.11.1
Time >=10cm from walls, locomotor time 10.20.20.60.80.70.70.70.60.40.4-0.30.40.40.4-0.5-0.6-0.40.3-0.40.1-0.60.2-0.2-0.10.6
Bouts of movement, locomotor time 10.10.10.6-0.3-0.2-0.1-0.1-0.2-0.0-0.10.0-0.3-0.1-0.10.40.40.1-0.20.1-0.0-0.1-0.40.40.8-0.5
Total resting periods, locomotor time 10.20.20.7-0.5-0.4-0.3-0.4-0.4-0.2-0.20.2-0.5-0.1-0.30.60.60.4-0.40.2-0.2-0.1-0.50.50.8-0.7
Rest time, locomotor task time 10.60.74.1-0.6-0.8-0.6-0.8-0.6-0.6-0.50.6-0.60.7-0.50.70.80.6-0.30.8-0.80.4-1.31.32.0-0.7
Distance moved, locomotor task time 10.71.02.11.21.41.21.31.11.11.0-1.00.8-1.41.0-1.0-1.0-0.90.6-0.80.9-0.50.9-0.9-1.30.5
Vertical activity count, locomotor time 10.20.52.90.50.70.50.60.50.50.4-0.50.3-0.90.4-0.5-0.4-0.40.0-0.70.6-0.31.1-1.1-1.70.0
Time >=10cm from walls, locomotor time 20.50.71.71.30.81.10.80.80.70.7-0.50.7-0.30.9-1.0-1.0-1.00.6-1.00.3-1.01.0-1.0-0.40.7
Bouts of movement, locomotor time 20.00.10.1-0.2-0.2-0.2-0.2-0.3-0.3-0.40.4-0.30.3-0.20.20.30.2-0.30.2-0.30.1-0.20.20.4-0.1
Total resting periods, locomotor time 20.10.10.4-0.3-0.2-0.3-0.2-0.3-0.4-0.40.4-0.20.6-0.20.20.40.2-0.20.2-0.30.1-0.20.20.50.0
Rest time, locomotor task time 20.81.11.80.71.20.81.21.21.11.1-1.31.21.01.2-1.2-1.0-1.31.3-0.81.3-0.90.1-0.10.20.9
Distance moved, locomotor task time 20.30.44.20.50.30.50.20.20.50.5-0.30.1-2.10.3-0.2-0.4-0.2-0.0-0.30.3-0.20.6-0.6-1.0-0.2
Vertical activity count, locomotor time 20.20.34.10.0-0.20.1-0.4-0.3-0.0-0.00.2-0.5-2.0-0.30.30.20.4-0.6-0.1-0.20.20.4-0.4-0.8-0.9
Light reinforcement 10.30.72.7-0.4-0.8-0.6-0.6-0.7-1.0-1.01.2-0.61.2-0.60.70.60.5-0.60.8-1.20.7-0.80.81.60.2
Light reinforcement 20.10.10.50.0-0.3-0.1-0.1-0.2-0.3-0.30.4-0.40.3-0.20.30.20.2-0.50.3-0.50.3-0.30.30.7-0.0
Bone: marrow area0.30.71.9-1.4-0.8-1.1-0.8-0.9-0.6-0.70.4-0.8-0.5-0.91.01.01.0-0.90.9-0.30.9-0.90.90.4-1.1
Bone: maximum diameter0.81.41.8-1.2-1.1-1.2-1.1-1.3-1.2-1.21.2-1.20.0-1.31.31.31.3-1.21.3-1.21.3-1.31.31.2-1.0
Bone: maximum force0.61.01.8-0.7-0.9-0.7-0.8-1.0-0.8-0.90.9-0.9-1.0-1.11.21.21.2-1.11.0-1.21.0-0.90.90.9-1.4
Bone: maximum moment0.71.22.1-0.8-1.0-0.7-0.9-1.1-0.9-0.91.0-1.0-1.4-1.21.21.31.3-1.21.1-1.31.1-1.01.01.0-1.5
Mean time between licks in bursts0.00.10.7-0.8-0.3-0.6-0.3-0.3-0.2-0.2-0.0-0.20.1-0.40.40.40.40.10.30.20.3-0.30.30.1-0.3
Mean num. licks in bursts0.00.10.60.20.20.30.20.20.30.2-0.2-0.0-0.80.2-0.2-0.2-0.20.0-0.00.2-0.00.0-0.0-0.2-0.2
Cd content in liver0.10.10.9-0.3-0.0-0.20.00.10.00.0-0.2-0.20.90.1-0.2-0.2-0.1-0.20.00.4-0.0-0.00.0-0.30.3
Co content in liver0.10.11.0-0.3-0.0-0.00.00.10.40.4-0.5-0.1-0.50.1-0.1-0.1-0.1-0.1-0.10.7-0.10.2-0.2-1.0-0.2
Cu content in liver1.82.23.91.11.91.32.01.71.61.6-1.80.80.11.6-1.6-1.6-1.60.8-1.51.8-1.41.3-1.3-0.71.9
Fe content in liver0.60.72.40.30.90.60.90.81.01.0-1.20.5-1.50.8-0.8-0.8-0.80.5-0.71.3-0.70.7-0.7-0.70.4
K content in liver0.00.00.30.1-0.30.1-0.2-0.00.10.1-0.0-0.1-0.6-0.1-0.0-0.00.1-0.10.0-0.1-0.00.1-0.1-0.2-0.2
Mg content in liver2.42.53.01.71.61.71.61.71.71.7-1.61.5-1.01.6-1.6-1.6-1.61.5-1.71.4-1.71.7-1.7-1.41.3
Mn content in liver4.04.45.72.12.22.02.22.22.02.0-2.02.20.12.3-2.3-2.3-2.22.2-2.31.9-2.32.2-2.2-1.62.4
Na content in liver1.61.82.5-1.3-1.3-1.4-1.3-1.3-1.4-1.41.3-1.61.2-1.31.31.31.3-1.61.3-1.31.3-1.41.41.5-0.6
Rb content in liver0.40.52.40.90.80.70.70.70.40.4-0.30.31.60.7-0.7-0.7-0.70.3-0.60.1-0.60.5-0.50.41.3
Se content in liver0.50.62.2-0.2-0.5-0.5-0.6-0.7-0.9-0.91.1-0.60.8-0.70.60.60.8-0.60.7-1.30.7-0.80.81.5-0.2
Sr content in liver2.01.82.91.11.11.31.21.31.51.5-1.51.4-1.31.2-1.2-1.2-1.21.4-1.41.5-1.41.5-1.5-1.70.6
Zn content in liver0.10.10.60.2-0.5-0.0-0.5-0.2-0.4-0.30.6-0.10.2-0.20.10.10.3-0.20.2-0.80.1-0.10.10.50.4
Bone: minimum diameter0.20.33.1-0.4-0.4-0.3-0.2-0.4-0.1-0.10.1-0.2-1.8-0.50.50.50.5-0.30.4-0.10.4-0.30.3-0.3-0.9
Time in familiar zone, hab. session 10.60.62.10.71.00.61.10.90.50.4-0.50.91.40.8-0.7-0.7-0.80.8-0.70.5-0.70.6-0.6-0.40.8
Time in novel zone, hab. session 13.13.14.2-1.4-1.8-1.5-1.8-1.8-1.8-1.71.9-2.00.2-1.81.91.81.9-2.01.8-2.11.8-1.81.82.1-1.3
Total zone transitions, hab. session 16.69.211.62.62.92.93.13.23.33.3-3.43.3-1.93.0-3.0-2.9-3.03.1-3.13.4-3.13.1-3.1-3.32.0
Total locomotion distance, hab. session 12.63.64.72.02.02.02.12.02.02.0-1.92.2-0.61.9-1.9-1.9-1.92.1-2.01.7-2.02.0-2.0-1.41.8
Locomotion velocity, hab. session 13.65.16.62.22.12.32.22.32.42.4-2.42.6-1.32.3-2.3-2.3-2.22.5-2.42.3-2.42.4-2.4-2.11.8
Time in familiar zone, hab. session 20.40.54.0-0.4-0.5-0.6-0.5-0.4-0.8-0.70.7-0.72.0-0.30.30.30.3-0.70.5-0.70.4-0.50.50.80.3
Time in novel zone, hab. session 20.20.22.20.30.20.40.20.00.30.3-0.20.5-1.5-0.00.10.10.00.5-0.1-0.1-0.10.2-0.2-0.1-0.4
Total zone transitions, hab. session 21.51.92.51.21.51.31.61.41.51.5-1.61.5-0.61.4-1.4-1.4-1.41.4-1.51.6-1.41.4-1.4-1.31.0
Total locomotion distance, hab. session 20.00.00.20.10.20.10.10.10.10.1-0.10.50.20.1-0.1-0.1-0.10.5-0.20.1-0.20.2-0.20.00.2
Locomotion velocity, hab. session 20.10.10.30.20.30.20.20.20.30.3-0.30.5-0.30.2-0.2-0.2-0.20.6-0.30.3-0.30.3-0.3-0.20.1
Novel to familiar place preference ratio0.91.04.90.61.00.80.90.61.11.1-1.20.6-2.20.7-0.7-0.7-0.70.9-0.81.2-0.70.8-0.8-1.3-0.3
Novelty place preference1.01.14.90.71.11.01.00.71.21.1-1.20.7-2.20.8-0.7-0.8-0.81.0-0.91.2-0.80.9-0.9-1.2-0.2
Time in novel zone, NPP test0.70.84.00.81.00.90.90.61.01.0-1.00.5-2.00.7-0.6-0.7-0.70.8-0.80.9-0.70.7-0.7-0.9-0.2
Total zone transitions, NPP test3.55.06.92.22.22.32.32.22.42.4-2.32.6-1.72.2-2.2-2.1-2.12.4-2.32.2-2.32.4-2.4-2.11.6
Total locomotion distance, NPP test0.91.32.81.21.11.21.11.11.11.2-1.11.7-0.71.1-1.1-1.0-1.01.4-1.20.8-1.21.2-1.2-0.71.1
Locomotion velocity, NPP test1.52.14.21.41.41.41.41.41.51.6-1.52.1-1.01.4-1.4-1.3-1.31.8-1.51.3-1.61.6-1.6-1.31.2
Intraocular pressure0.81.22.40.71.40.91.20.91.31.2-1.41.0-1.31.0-0.9-0.8-1.11.0-1.01.5-0.90.9-0.9-1.60.1
Delta distance traveled before/after self-admin0.70.81.3-1.1-0.7-1.0-1.1-1.0-0.8-0.80.7-1.1-0.0-1.01.00.91.0-1.10.8-0.50.9-0.80.80.3-1.0
Delta ambulatory time before/after self-admin0.60.81.4-1.0-0.7-1.0-1.2-1.0-0.9-0.90.8-1.0-0.2-1.11.01.01.0-1.10.7-0.70.7-0.60.60.2-1.0
Parametrial fat weight0.20.51.0-0.0-0.6-0.1-0.4-0.6-0.5-0.50.7-1.0-0.9-0.60.60.60.5-1.00.7-0.80.8-0.70.70.8-0.9
Pavlov. Cond. lever latency1.62.14.4-1.8-1.3-1.5-1.4-1.6-1.0-1.10.9-1.6-1.2-1.51.71.61.5-1.41.5-0.81.6-1.51.50.7-2.1
Pavlov. Cond. magazine entry latency0.40.53.70.8-0.10.3-0.10.0-0.6-0.60.90.01.9-0.0-0.0-0.00.0-0.10.1-1.20.1-0.20.21.40.9
Pavlov. Cond. change in total contacts1.81.94.32.11.51.71.61.51.01.0-0.71.41.01.5-1.6-1.6-1.51.2-1.40.5-1.41.3-1.3-0.41.8
Pavlov. Cond. index score0.70.93.61.60.81.10.81.00.20.30.10.91.90.9-1.0-0.9-0.90.7-0.8-0.4-0.80.7-0.70.41.7
Pavlov. Cond. latency score0.81.02.91.60.81.20.81.00.40.4-0.11.11.71.0-1.1-1.0-1.00.9-0.9-0.1-1.00.9-0.90.21.7
Pavlov. Cond. lever contacts2.32.76.22.01.51.71.61.81.21.2-1.01.71.51.8-1.9-1.9-1.81.6-1.70.9-1.81.7-1.7-0.72.5
Pavlov. Cond. magazine entry number0.60.75.4-1.4-0.4-0.8-0.4-0.60.20.2-0.6-0.5-2.3-0.60.70.70.6-0.40.40.80.5-0.30.3-1.0-1.5
Pavlov. Cond. intertrial magazine entries0.50.73.10.41.00.71.00.71.00.9-1.10.7-1.80.5-0.4-0.5-0.60.7-0.70.9-0.60.7-0.7-0.7-0.1
Pavlov. Cond. lever-magazine prob. diff.0.70.93.31.60.71.10.80.90.20.20.20.91.80.8-1.0-0.9-0.80.7-0.8-0.5-0.80.7-0.70.51.7
Pavlov. Cond. response bias0.91.14.51.60.81.10.91.10.20.30.10.72.11.0-1.2-1.1-1.00.7-0.8-0.3-0.90.7-0.70.51.9
Pavlov. Cond. lever latency0.40.61.00.60.90.70.90.90.90.8-0.90.6-0.30.9-0.7-0.7-0.90.6-0.81.0-0.70.7-0.7-0.80.5
Pavlov. Cond. magazine entry latency0.30.40.90.60.30.60.50.50.60.7-0.60.8-1.00.6-0.5-0.6-0.60.9-0.50.6-0.60.6-0.6-0.60.3
Pavlov. Cond. change in total contacts0.20.30.6-0.3-0.6-0.4-0.6-0.6-0.6-0.60.7-0.10.6-0.60.40.40.6-0.10.5-0.80.4-0.40.40.8-0.1
Pavlov. Cond. index score0.20.30.5-0.4-0.7-0.4-0.7-0.6-0.6-0.50.6-0.1-0.1-0.60.50.50.6-0.10.5-0.70.5-0.40.40.4-0.4
Pavlov. Cond. latency score0.10.10.3-0.2-0.5-0.2-0.5-0.4-0.3-0.30.40.1-0.4-0.40.30.30.40.10.3-0.50.3-0.20.20.2-0.3
Pavlov. Cond. lever contacts0.40.51.0-0.5-0.9-0.7-0.8-0.8-0.9-0.80.9-0.50.6-0.80.60.60.8-0.60.7-1.00.7-0.70.70.8-0.3
Pavlov. Cond. magazine entry number0.00.00.4-0.20.3-0.10.20.10.10.0-0.2-0.30.60.1-0.1-0.1-0.1-0.4-0.10.3-0.10.0-0.0-0.10.1
Pavlov. Cond. intertrial magazine entries1.82.73.81.11.91.31.71.71.71.7-1.91.9-0.81.6-1.6-1.6-1.61.9-1.71.9-1.71.7-1.7-1.71.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.4-0.8-0.5-0.7-0.6-0.5-0.50.6-0.0-0.1-0.60.50.50.6-0.00.5-0.70.5-0.40.40.4-0.4
Pavlov. Cond. response bias0.60.81.4-0.6-1.0-0.8-1.0-1.0-1.0-1.01.1-0.80.5-0.90.80.80.9-0.80.9-1.20.9-0.80.81.1-0.4
Time in closed arm before self-admin1.11.43.1-0.8-1.3-1.0-1.3-1.1-1.4-1.31.5-1.01.7-1.11.11.11.2-1.00.9-1.80.9-0.80.81.60.2
Time in closed arm after self-admin1.11.11.6-1.2-1.1-1.2-1.1-1.1-1.0-1.00.9-1.30.1-1.11.11.11.1-1.11.1-0.81.0-1.21.21.1-1.0
Time in open arm before self-admin0.10.10.5-0.50.5-0.20.2-0.00.30.2-0.50.1-0.7-0.1-0.1-0.0-0.00.1-0.10.6-0.20.1-0.1-0.6-0.2
Time in open arm after self-admin2.02.23.71.21.61.31.51.51.51.5-1.61.6-0.11.4-1.6-1.4-1.51.5-1.51.5-1.51.6-1.6-1.61.9
Bone: periosteal estimation0.51.01.5-1.1-1.0-1.0-0.8-1.1-0.9-0.90.9-0.8-0.6-1.11.21.21.2-1.01.0-0.91.1-1.01.00.9-1.1
Bone: periosteal perimeter0.61.01.7-1.3-1.1-1.2-1.0-1.1-0.9-0.90.8-0.9-0.3-1.11.11.11.2-1.01.1-0.71.0-1.01.00.6-1.0
Bone: post-yield work0.30.41.6-0.7-0.3-0.5-0.2-0.5-0.3-0.40.3-0.9-1.3-0.60.80.80.6-1.00.6-0.30.7-0.70.70.4-1.0
Progressive ratio test 1 active lever presses0.20.20.90.80.40.70.50.40.40.4-0.20.3-0.90.4-0.5-0.4-0.40.3-0.50.2-0.20.3-0.3-0.3-0.0
Progressive ratio test 1 breakpoint0.10.20.70.70.40.70.50.30.40.4-0.20.3-0.80.3-0.5-0.4-0.40.3-0.50.1-0.20.3-0.3-0.3-0.1
Progressive ratio test 1 inactive lever presses0.00.00.10.1-0.40.0-0.2-0.1-0.1-0.10.2-0.10.3-0.1-0.10.10.00.0-0.0-0.20.20.4-0.4-0.10.2
Progressive ratio test 2 active lever presses0.00.00.10.40.10.30.10.10.00.10.10.30.20.1-0.3-0.1-0.10.3-0.2-0.0-0.20.1-0.1-0.3-0.1
Progressive ratio test 2 breakpoint0.00.10.20.50.10.30.20.20.10.10.00.30.10.2-0.3-0.2-0.10.3-0.20.0-0.30.2-0.2-0.4-0.1
Progressive ratio test 2 inactive lever presses0.00.10.60.10.10.20.10.20.20.2-0.30.1-0.30.1-0.3-0.1-0.20.1-0.10.40.00.1-0.1-0.8-0.3
Incentive Sensitization - Responses0.00.10.90.2-0.30.0-0.30.0-0.1-0.10.20.30.90.1-0.1-0.10.00.30.2-0.1-0.1-0.10.1-0.2-0.0
Incentive Sensitization - Breakpoint0.10.10.60.0-0.5-0.1-0.5-0.1-0.3-0.20.30.10.8-0.10.00.10.20.10.3-0.20.1-0.30.3-0.2-0.2
Sum of active levers in priming session hrs 5-63.53.35.11.91.81.92.02.01.81.8-1.81.7-1.02.0-1.9-2.1-2.11.6-1.82.0-1.41.7-1.7-2.30.6
Progressive ratio0.71.13.60.90.50.90.91.10.91.0-0.91.40.61.3-1.2-1.3-1.21.3-0.71.0-0.90.8-0.8-0.71.9
Food seeking constrained by brief footshock0.60.81.2-0.7-0.7-0.8-0.8-0.9-1.0-1.01.1-0.90.1-0.91.10.90.7-0.80.9-1.00.7-1.01.01.0-1.1
Seeking ratio, punishment vs. effort0.71.04.9-0.6-0.1-0.6-0.6-0.9-0.7-0.90.8-1.3-1.0-1.01.21.10.9-1.20.8-0.80.9-1.01.00.9-2.2
Retroperitoneal fat weight0.52.13.2-1.0-1.4-1.0-1.6-1.5-1.4-1.41.6-1.4-0.5-1.51.61.51.4-1.41.5-1.81.6-1.51.51.8-1.6
Reaction time number correct0.20.50.70.30.50.40.70.80.60.7-0.80.7-0.30.7-0.7-0.7-0.60.8-0.80.8-0.80.8-0.8-0.60.8
Reaction time mean minus median0.10.10.60.20.80.30.50.30.30.3-0.40.20.30.2-0.4-0.4-0.30.3-0.40.2-0.30.2-0.20.40.6
Reaction time mean minus median AUC0.10.31.40.50.90.40.60.50.30.2-0.30.41.00.3-0.5-0.5-0.40.5-0.6-0.0-0.50.4-0.40.71.2
Reaction time num false alarms0.20.30.60.80.40.60.40.60.40.4-0.30.3-0.30.5-0.5-0.5-0.50.3-0.60.1-0.60.6-0.6-0.80.4
Reaction time num false alarms AUC0.20.30.70.80.50.70.40.60.50.5-0.40.3-0.60.6-0.6-0.6-0.50.3-0.60.2-0.60.6-0.6-0.80.4
Reaction time trials correct on left0.20.50.70.30.50.40.70.80.60.7-0.80.7-0.30.7-0.7-0.7-0.60.8-0.80.8-0.80.8-0.8-0.60.8
Reaction time trials on left0.20.50.70.30.60.40.70.80.60.7-0.70.7-0.30.7-0.7-0.7-0.60.8-0.80.8-0.80.8-0.8-0.60.8
Reaction time mean0.30.41.9-0.7-0.0-0.7-0.2-0.6-0.6-0.70.5-0.71.1-0.70.60.60.6-0.60.5-0.60.6-0.70.71.40.0
Reaction time mean AUC0.20.41.8-0.70.0-0.6-0.2-0.5-0.5-0.60.4-0.61.2-0.60.50.50.6-0.50.5-0.50.6-0.70.71.30.1
Median of all reaction times0.71.02.6-1.0-0.4-1.0-0.6-0.9-1.0-1.00.9-1.01.5-1.00.90.91.0-0.90.9-0.91.0-1.11.11.6-0.2
Reaction time omissions0.10.10.60.40.70.40.50.10.20.1-0.10.2-0.70.1-0.0-0.1-0.20.4-0.2-0.1-0.10.0-0.00.8-0.1
Reaction time false alarm rate0.00.00.20.50.00.3-0.10.0-0.1-0.10.2-0.2-0.30.0-0.0-0.00.0-0.3-0.0-0.4-0.00.0-0.0-0.3-0.2
Reaction time premature initiation rate0.20.30.80.90.60.80.50.40.60.6-0.40.6-0.20.5-0.6-0.6-0.60.6-0.60.2-0.60.6-0.60.40.9
Reaction time premature initiations0.61.01.61.01.01.00.90.91.01.1-1.01.1-0.61.0-1.1-1.1-1.01.1-1.10.8-1.11.1-1.1-0.21.3
Std. dev. reaction times0.00.10.50.10.50.10.20.00.10.0-0.10.10.3-0.1-0.0-0.00.10.2-0.2-0.1-0.10.0-0.00.70.4
Reaction time trials completed0.20.50.70.30.60.40.70.80.60.7-0.70.7-0.30.7-0.7-0.7-0.60.8-0.80.8-0.80.8-0.8-0.60.8
Reaction time trials AUC0.30.50.90.40.60.40.70.80.70.7-0.80.7-0.20.7-0.7-0.7-0.60.8-0.80.8-0.80.8-0.8-0.60.9
Run reversals in cocaine runway, females0.30.33.8-0.00.20.20.10.10.40.3-0.4-0.0-1.90.1-0.0-0.10.0-0.00.30.60.4-0.50.5-0.4-1.3
Run reversals in cocaine runway, males0.91.06.1-0.9-0.9-1.1-0.9-0.7-1.1-1.11.0-0.52.5-0.80.70.80.8-0.60.7-0.90.7-0.70.71.2-0.0
Latency to leave start box in cocaine runway2.02.34.8-2.2-1.9-2.0-1.8-1.7-1.5-1.51.2-1.80.7-1.61.51.51.7-1.91.4-1.01.5-1.11.10.5-1.0
Latency to leave start box in cocaine runway, F2.83.26.2-2.5-2.3-2.3-2.2-2.0-1.7-1.71.5-1.80.4-1.91.92.02.1-1.91.7-1.41.7-1.41.41.0-0.9
Latency to leave start box in cocaine runway, M0.40.41.3-0.8-0.5-0.6-0.4-0.5-0.5-0.50.4-1.00.4-0.50.40.30.5-1.10.6-0.10.8-0.50.5-0.1-1.0
Std. dev. time between licks in bursts1.11.62.4-1.6-1.3-1.5-1.3-1.3-1.2-1.31.1-1.20.9-1.31.31.31.3-1.21.3-1.01.3-1.31.31.0-1.0
Total sessions with >9 infusions0.10.10.3-0.1-0.6-0.1-0.4-0.4-0.3-0.20.3-0.30.0-0.30.20.30.4-0.20.2-0.40.3-0.30.3-0.0-0.4
Short access day 1 total inactive lever presses4.25.57.52.72.22.62.62.62.22.2-2.12.40.22.6-2.7-2.5-2.62.4-2.31.9-2.32.4-2.4-1.92.7
Short access day 10 total inactive lever presses0.10.44.2-0.8-0.4-0.8-0.5-0.2-0.5-0.50.3-0.02.1-0.10.10.20.20.10.1-0.10.10.3-0.30.21.1
Short access day 1 total infusions0.00.00.2-0.1-0.4-0.1-0.2-0.2-0.2-0.10.2-0.20.4-0.1-0.00.10.2-0.30.2-0.10.2-0.30.30.00.2
Short access day 10 total infusions0.50.71.7-0.6-1.1-0.6-0.9-0.7-0.8-0.80.8-0.80.6-0.70.60.70.7-0.80.8-0.60.9-1.11.10.3-1.3
Short access total infusions0.10.20.4-0.4-0.6-0.3-0.4-0.5-0.4-0.30.4-0.60.2-0.40.20.40.4-0.60.4-0.30.5-0.60.60.1-0.4
Short access day 1 locomotion1.11.42.7-0.8-1.6-1.0-1.4-1.3-1.2-1.21.3-1.01.1-1.21.11.21.2-1.11.1-1.31.1-1.21.21.2-0.6
Short access day 10 total locomotion1.22.34.1-1.0-1.8-1.3-1.8-1.5-1.8-1.72.0-1.31.3-1.41.41.41.4-1.21.5-2.01.6-1.51.51.6-0.7
Short access total locomotion1.01.22.3-0.9-1.5-1.0-1.3-1.2-1.2-1.11.3-1.10.9-1.11.01.21.2-1.00.9-1.41.1-1.01.00.8-0.5
One hour access (0.3 mA shock)0.30.30.50.70.70.60.50.60.60.6-0.50.40.00.6-0.7-0.7-0.60.4-0.40.5-0.50.3-0.3-0.70.5
Compulsive drug intake3.33.95.62.32.12.42.22.22.22.2-2.01.9-0.72.3-2.1-2.3-2.31.9-1.81.8-2.01.5-1.5-1.11.9
One hour access (shock baseline)1.21.92.5-1.5-1.4-1.5-1.5-1.5-1.4-1.51.4-1.40.5-1.51.41.51.6-1.41.3-1.21.4-1.21.20.5-1.5
Social response proportion0.80.95.01.21.11.20.90.81.01.0-0.81.0-2.20.7-0.6-0.6-0.71.0-0.90.6-0.80.9-0.9-0.50.3
Social responses0.10.11.30.30.20.30.20.00.10.1-0.00.3-1.10.10.00.0-0.10.3-0.1-0.0-0.00.1-0.10.1-0.2
Social time0.10.10.6-0.40.0-0.40.0-0.1-0.3-0.40.2-0.80.5-0.10.20.10.1-0.70.40.00.5-0.60.60.4-0.2
Soleus weight1.02.93.9-1.3-1.8-1.5-1.9-1.8-1.8-1.82.0-1.40.2-1.81.81.81.9-1.41.8-2.01.7-1.71.71.9-1.6
Bone: stiffness0.10.10.6-0.1-0.1-0.1-0.2-0.4-0.2-0.20.3-0.4-0.8-0.40.50.50.5-0.50.3-0.60.3-0.20.20.5-0.3
Tibialis anterior weight0.31.02.50.30.80.60.80.81.21.2-1.31.0-1.00.8-0.8-0.8-0.81.1-0.91.5-0.91.0-1.0-1.60.2
Time to tail flick, vehicle, before self-admin4.54.76.72.42.52.42.62.52.22.1-2.12.0-0.42.4-2.2-2.4-2.32.0-2.12.1-2.21.9-1.9-2.21.5
Time to tail flick, vehicle, after self-admin0.30.42.4-0.5-0.3-0.5-0.2-0.3-0.5-0.50.4-0.61.6-0.30.40.40.5-0.60.7-0.30.8-0.70.70.80.2
Time to tail flick, test, before self-admin0.10.10.4-0.5-0.4-0.5-0.1-0.2-0.3-0.30.1-0.30.2-0.30.40.30.2-0.10.40.00.4-0.60.6-0.1-0.5
Time to tail flick, test, after self-admin0.30.31.3-0.4-0.1-0.4-0.3-0.5-0.4-0.50.5-0.6-0.1-0.50.70.50.4-0.40.3-0.30.4-0.70.70.5-1.1
Delta time to tail flick, vehicle, before/after SA3.83.65.1-1.8-2.0-1.9-2.0-2.0-2.0-2.02.0-1.71.8-1.91.82.01.9-1.72.0-1.92.0-1.91.92.3-1.0
Delta time to tail flick, test, before/after SA0.20.30.91.00.70.80.40.40.40.4-0.20.5-0.30.5-0.4-0.6-0.50.5-0.6-0.0-0.60.4-0.40.3-0.2
Tibia length0.30.93.8-1.0-0.8-0.8-0.7-0.9-0.4-0.40.4-0.9-2.0-1.11.11.11.2-0.90.8-0.60.8-0.70.70.1-1.5
Ambulatory time before self-admin0.00.10.2-0.1-0.3-0.1-0.1-0.00.00.0-0.10.1-0.5-0.00.10.10.1-0.00.30.00.3-0.40.40.4-0.4
Ambulatory time after self-admin1.31.64.2-1.5-1.1-1.2-1.5-1.3-0.9-0.90.8-1.3-1.5-1.21.31.21.3-1.51.3-0.51.3-1.31.30.3-2.0
Bone: tissue strength0.00.00.2-0.5-0.2-0.4-0.2-0.2-0.1-0.10.0-0.2-0.3-0.20.10.10.1-0.20.20.10.2-0.20.2-0.1-0.2
Total heroin consumption1.11.32.21.11.41.11.31.31.00.9-1.01.20.11.3-1.1-1.3-1.51.2-1.11.2-0.91.1-1.1-1.10.8
Bone: trabecular number1.22.04.7-0.5-1.2-0.8-1.1-1.2-1.6-1.61.9-1.31.2-1.41.41.51.3-1.31.4-2.21.4-1.41.42.1-0.6
Bone: trabecular spacing0.20.20.6-0.00.20.00.00.30.30.4-0.50.40.60.4-0.6-0.6-0.50.3-0.40.7-0.40.4-0.4-0.80.6
Bone: trabecular thickness2.22.83.8-1.5-1.8-1.5-1.6-1.9-1.5-1.51.6-1.5-0.2-1.91.91.91.9-1.61.8-1.71.8-1.71.71.4-1.9
Bone: trabecular tissue density0.20.20.60.40.20.40.20.40.40.4-0.40.80.40.5-0.5-0.4-0.50.8-0.50.5-0.60.6-0.6-0.60.4
Water consumed over 24 hours0.10.20.30.30.40.30.50.50.40.4-0.40.20.00.5-0.4-0.4-0.50.2-0.50.5-0.50.4-0.4-0.30.4
Number of responses in last shaping day0.10.11.3-0.5-0.6-0.5-0.3-0.3-0.3-0.30.2-0.11.1-0.30.20.30.3-0.20.20.00.1-0.20.2-0.4-0.2