Hub : Genes

Ogfod3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Ogfod3	0.05	0.03	2.8e-07	0.06	0.05	0.05	0.04	2.3e-07	2.3e-06	3.0e-06	1.1e-05
2	Brain	mRNA stability	Ogfod3	0.07	0.05	3.1e-05	0.05	0.05	0.04	0.04	2.6e-05	2.0e-05	1.9e-04	1.3e-04
3	Adipose	gene expression	Ogfod3	0.08	0.05	6.0e-09	0.06	0.06	0.07	0.07	1.8e-07	1.8e-07	2.9e-08	4.3e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.1	0.2	0.6	-0.1	-0.0	0.8
Area under the delay curve	1.4	1.6	1.6	-1.2	1.3	-1.3
BMI with tail	0.1	0.2	0.3	0.6	-0.3	0.4
BMI without tail	1.3	4.1	8.5	1.3	-1.4	2.9
Body weight	1.3	5.7	6.8	2.6	-2.4	2.2
Weight adjusted by age	1.2	1.8	2.0	1.4	-1.4	1.2
Bone surface	0.3	0.6	1.0	0.8	-0.5	1.0
Bone volume	0.3	0.5	1.1	0.6	-0.5	1.0
Breakpoint value in progressive ratio session	1.6	2.0	3.0	1.7	-1.7	-0.2
Number of licking bursts	0.1	0.2	0.5	-0.3	0.4	0.7
Context. condit. distance diff. score	1.0	1.2	2.2	-1.0	0.6	1.5
Locomotion velocity, session 1	1.0	1.1	3.2	0.2	0.2	-1.8
Locomotion distance, session 1	3.4	4.2	5.5	-2.1	2.3	-1.7
Locomotion velocity, session 2	3.0	3.5	5.7	-1.5	1.7	-2.4
Locomotion distance, session 2	1.0	1.3	1.9	-1.4	1.4	-0.5
Locomotion velocity, session 3	1.3	1.4	3.3	-0.5	0.9	-1.8
Locomotion distance, session 3	3.1	3.4	5.2	-1.4	1.7	-2.3
Stereotopy head waving bouts, day 3	0.4	0.5	1.3	0.0	0.3	-1.2
Stereotopy head waving duration, day 3	0.4	0.5	1.0	-0.3	0.5	-1.0
Locomotion velocity, session 7	0.6	0.7	1.0	-0.7	1.0	-0.7
Locomotion distance, session 7	3.3	4.2	5.9	-2.3	2.4	-1.1
Stereotopy head waving bouts, day 7	0.1	0.1	0.1	0.4	-0.4	0.4
Stereotopy head waving duration, day 7	0.1	0.1	0.2	0.3	-0.3	0.4
Locomotion velocity, session 8	1.3	1.6	2.4	-1.6	1.5	-0.4
Locomotion distance, session 8	2.0	2.9	4.8	-2.2	1.7	1.0
Degree of sensitization distance	0.7	0.7	2.1	-0.1	-0.2	1.4
Degree of sensitization stereotypy	0.2	0.2	0.4	0.1	-0.3	0.6
Conditioned locomotion	2.3	2.7	6.7	0.4	-1.1	2.6
Cocaine response after cond. corrected	0.2	0.3	0.5	0.4	-0.3	-0.7
Cocaine response after cond. not corrected	0.4	0.5	1.5	-0.0	0.3	-1.2
Cocaine response before conditioning	1.4	1.6	2.4	-1.3	1.5	-0.9
Saline control response	1.6	2.1	4.4	0.8	-1.2	2.1
Bone: connectivity density	0.3	0.5	0.6	-0.8	0.6	0.6
Bone: cortical apparent density	1.7	2.3	3.4	-1.2	1.5	-1.8
Bone: cortical area	2.8	4.3	6.8	2.6	-2.1	1.2
Bone: cortical porosity	2.7	3.0	5.5	2.3	-1.8	-0.3
Bone: cortical porosity	2.9	3.2	5.7	2.4	-2.0	0.2
Bone: cortical thickness	3.0	4.9	8.9	3.0	-2.4	0.6
Bone: cortical thickness	0.8	0.9	1.8	1.3	-1.0	-0.1
Bone: cortical tissue density	1.8	2.4	3.5	-1.2	1.5	-1.9
Condit. Reinf. active minus inactive responses	1.5	1.7	2.8	0.8	-1.2	1.7
Condit. Reinf. active-inactive response ratio	0.4	0.5	0.6	0.6	-0.6	0.7
Condit. Reinf. active responses	3.0	3.7	6.9	1.1	-1.7	2.6
Condit. Reinf. inactive responses	1.1	1.4	2.9	0.5	-1.0	1.7
Incentive salience index mean	1.2	1.4	2.9	0.6	-1.0	1.7
Condit. Reinf. lever presses	0.2	0.4	0.5	-0.7	0.5	0.6
Condit. Reinf. active minus inactive responses	0.2	0.2	0.4	0.3	-0.4	0.7
Condit. Reinf. active-inactive response ratio	1.8	2.0	2.5	1.6	-1.6	1.1
Condit. Reinf. active responses	0.1	0.1	0.1	-0.3	0.1	0.4
Condit. Reinf. inactive responses	0.9	1.2	1.8	-1.4	1.1	-0.6
Condit. Reinf. lever presses	0.2	0.3	0.6	-0.4	0.2	0.8
Condit. Reinf. lever reinforcers received	0.1	0.2	0.3	-0.5	0.2	0.5
Conditioned reinforcement - actives	0.2	0.3	0.5	-0.6	0.7	-0.3
Conditioned reinforcement - inactives	0.2	0.2	0.4	0.4	-0.6	0.4
Conditioned locomotion	0.1	0.1	0.2	-0.4	0.4	0.2
Patch foraging indifference point 0 sec	0.1	0.1	0.4	0.1	-0.2	0.6
Patch foraging indifference point AUC	0.1	0.1	0.4	-0.1	-0.0	0.6
Delay disc. indifference point, 0s delay	0.1	0.2	0.3	-0.2	0.4	-0.5
Delay disc. indifference point, 16s delay	2.5	2.8	4.5	-2.1	1.9	-0.6
Delay disc. indifference point, 2s delay	0.3	0.4	0.9	-0.3	0.3	-1.0
Delay disc. indifference point, 24s delay	2.5	2.8	5.3	-1.1	1.4	-2.3
Delay disc. indifference point, 4s delay	0.4	0.4	1.0	-0.2	0.5	-1.0
Delay disc. indifference point, 8s delay	0.4	0.5	1.2	-0.3	0.4	-1.1
Indifference point function ln k	0.9	1.6	2.0	-1.0	1.4	-1.4
Indifference point function log k	0.9	1.6	2.0	-1.0	1.4	-1.4
Patch foraging total patch changes 0 sec	0.1	0.1	0.4	0.1	-0.2	0.7
Patch foraging total patch changes 12 sec	0.4	0.5	0.5	0.7	-0.7	0.7
Patch foraging total patch changes 18 sec	0.2	0.4	0.5	-0.7	0.5	0.6
Patch foraging total patch changes 24 sec	0.3	0.5	0.9	0.4	-0.7	1.0
Patch foraging total patch changes 6 sec	0.4	0.7	0.7	0.8	-0.8	0.9
Patch foraging time to switch 0 sec	0.1	0.3	0.4	-0.4	0.6	-0.6
Patch foraging water rate 0 sec	0.8	1.6	2.7	0.8	-1.3	1.6
Patch foraging water rate 12 sec	0.1	0.1	0.3	-0.5	0.2	0.2
Patch foraging water rate 18 sec	0.1	0.2	0.4	-0.4	0.2	0.6
Patch foraging water rate 24 sec	0.5	0.8	2.0	-0.3	-0.3	1.4
Patch foraging water rate 6 sec	0.1	0.1	0.1	-0.3	0.2	-0.3
Seeking ratio, delayed vs. immediate footshock	0.7	0.8	1.3	0.7	-0.8	1.1
Distance traveled before self-admin	1.1	1.5	2.4	1.5	-1.4	0.4
Distance traveled after self-admin	0.6	0.7	1.7	0.3	-0.6	1.3
Extensor digitorum longus weight	0.2	0.6	0.9	-0.5	0.8	1.0
Bone: elastic displacement	1.2	1.4	2.1	1.5	-1.2	0.8
Bone: elastic work	7.4	9.7	15.3	3.9	-3.4	1.4
Bone: endosteal estimation	0.2	0.5	0.6	-0.8	0.6	0.6
Bone: endosteal perimeter	0.5	1.1	1.2	1.1	-1.0	1.1
Epididymis fat weight	0.4	1.5	3.2	0.8	-0.8	1.8
Delta time in closed arm before/after self-admin	1.0	0.9	1.5	-1.2	1.1	0.2
Delta time in open arm before/after self-admin	0.0	0.0	0.0	-0.1	-0.1	-0.1
Diff in mean of infusions in LGA sessions	0.3	0.4	0.7	0.8	-0.7	-0.1
Delay discount exponential model param	1.6	1.8	2.7	1.1	-1.2	1.6
Extinction: sum of active levers before priming	0.5	0.5	1.6	-0.1	0.2	-1.3
Active lever presses in extinction session 6	1.9	1.9	3.5	1.3	-0.8	-1.9
Bone: final force	2.9	4.6	6.0	2.5	-2.2	1.7
Bone: final moment	3.9	6.2	8.4	2.9	-2.6	1.9
Food consumed during 24 hour testing period	0.4	0.5	1.1	0.5	-0.5	1.1
Glucose	4.3	6.8	20.0	0.6	-0.1	-4.5
Heart weight	0.7	1.1	1.7	1.3	-1.3	0.3
Delay discount hyperbolic model param	1.5	1.6	2.6	1.0	-1.1	1.6
Intermittent access intake day 1-15 change	1.1	2.2	2.7	1.6	-1.6	1.1
Intermittent access intake escalation	0.9	1.8	2.2	1.5	-1.5	1.0
Intermittent access intake escalation 2	3.5	4.0	5.6	2.3	-2.4	0.9
Intermitt. access day 1 inactive lever presses	0.6	2.2	4.6	0.8	-1.1	2.2
Intermitt. access day 15 inactive lever presses	0.3	0.7	1.9	-0.2	-0.2	1.4
Intermitt. access escalation Index	0.4	0.6	1.6	-0.3	-0.0	1.3
Intermittent access day 1 total infusions	0.0	0.0	0.1	0.1	0.1	0.2
Intermittent access day 15 total infusions	0.5	0.8	1.2	0.8	-0.8	1.1
Intermittent access terminal intake (last 3 days)	0.9	1.2	1.5	1.0	-1.1	1.2
Intermittent access total infusions	0.2	0.2	0.5	0.4	-0.3	0.7
Intermittent access day 1 locomotion	0.1	0.1	0.1	-0.3	0.4	-0.2
Intermittent access day 15 total locomotion	0.4	0.6	0.7	0.8	-0.8	0.8
Intermittent access total locomotion	0.1	0.1	0.2	0.4	-0.3	0.4
Intermittent access standard deviation	0.4	0.9	1.1	1.1	-0.6	-1.1
Left kidney weight	0.1	0.4	0.6	0.8	-0.4	-0.6
Right kidney weight	0.1	0.2	0.6	0.4	-0.0	-0.8
Cocaine induced anxiety	3.0	4.2	6.9	2.6	-2.2	-0.9
Post-drug Anxiety	2.2	2.4	3.2	1.8	-1.4	-1.4
Baseline Anxiety	0.8	0.9	1.4	-1.2	1.1	-0.5
Tail length	2.5	9.8	14.4	2.6	-2.9	3.8
Length with tail	1.5	6.6	9.7	3.1	-2.8	1.5
Length without tail	1.0	3.1	4.9	2.2	-1.7	-1.3
Times rat made contact with spout	3.2	3.7	4.0	2.0	-2.0	1.7
Lifetime Intake	0.0	0.0	0.1	0.1	-0.0	0.3
Liver weight, left	0.7	1.2	3.0	-0.1	0.7	-1.7
Liver weight, right	0.9	1.6	2.5	1.2	-0.9	1.6
Locomotor activity	0.5	0.7	0.9	-0.8	0.8	-1.0
Locomotor testing distance	1.6	2.9	3.3	-1.8	1.8	-1.5
Locomotor testing rearing	0.5	1.0	1.9	-1.4	1.0	-0.3
Locomotion in novel chamber	0.6	0.8	1.2	-1.1	1.0	-0.4
Locomotion in novel chamber post-restriction	2.8	4.6	6.8	1.7	-2.0	2.6
Fecal boli incidents, locomotor time 1	0.4	0.6	0.9	-0.9	1.0	-0.2
Change in fecal boli incidents, locomotor task	0.8	0.8	2.0	0.5	-0.3	-1.4
Time >=10cm from walls, locomotor time 1	1.1	1.2	3.4	-0.5	0.1	1.8
Bouts of movement, locomotor time 1	1.2	1.4	2.7	-0.6	1.0	-1.7
Total resting periods, locomotor time 1	1.3	1.5	3.2	-0.4	1.0	-1.8
Rest time, locomotor task time 1	0.4	0.5	1.1	0.6	-0.1	-1.0
Distance moved, locomotor task time 1	0.1	0.2	0.5	-0.0	-0.3	0.7
Vertical activity count, locomotor time 1	0.1	0.3	0.9	-0.2	-0.3	0.9
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.1	0.1	0.1	0.3
Bouts of movement, locomotor time 2	0.8	1.3	1.5	-1.0	1.2	-1.2
Total resting periods, locomotor time 2	0.7	1.1	1.5	-1.1	1.2	-0.8
Rest time, locomotor task time 2	0.0	0.0	0.0	-0.0	0.1	0.0
Distance moved, locomotor task time 2	0.0	0.0	0.1	-0.1	0.1	-0.3
Vertical activity count, locomotor time 2	0.2	0.2	0.4	-0.6	0.5	-0.2
Light reinforcement 1	0.4	1.1	3.0	-0.5	-0.0	1.7
Light reinforcement 2	0.7	1.0	2.5	0.3	-0.7	1.6
Bone: marrow area	0.2	0.4	0.6	-0.8	0.6	0.6
Bone: maximum diameter	0.7	1.3	2.3	1.5	-1.1	0.6
Bone: maximum force	2.6	4.6	5.3	2.3	-2.2	1.9
Bone: maximum moment	3.4	6.0	7.4	2.7	-2.6	2.0
Mean time between licks in bursts	0.7	1.7	2.0	-1.1	1.4	-1.4
Mean num. licks in bursts	0.8	1.3	2.0	1.3	-1.4	0.5
Cd content in liver	0.7	0.7	1.2	-1.0	1.1	0.0
Co content in liver	0.1	0.1	0.1	0.4	-0.1	0.4
Cu content in liver	1.4	1.7	2.7	1.6	-1.4	0.6
Fe content in liver	0.6	0.8	1.2	-0.9	1.1	-0.5
K content in liver	1.1	1.0	2.9	-0.3	0.1	1.7
Mg content in liver	1.6	1.6	2.6	-1.2	0.9	1.6
Mn content in liver	0.0	0.0	0.0	0.0	0.0	-0.0
Na content in liver	0.2	0.3	0.4	-0.6	0.6	0.1
Rb content in liver	1.0	1.1	3.2	-0.1	-0.4	1.8
Se content in liver	0.3	0.4	1.1	-0.1	-0.4	1.0
Sr content in liver	0.6	0.5	0.6	0.8	-0.6	-0.7
Zn content in liver	1.5	1.6	3.5	0.8	-0.9	1.9
Bone: minimum diameter	2.1	3.8	5.0	2.2	-1.9	1.6
Time in familiar zone, hab. session 1	0.2	0.1	0.3	0.3	-0.5	-0.3
Time in novel zone, hab. session 1	0.1	0.1	0.1	-0.2	0.3	0.2
Total zone transitions, hab. session 1	0.4	0.6	0.7	-0.8	0.8	-0.7
Total locomotion distance, hab. session 1	0.1	0.2	0.3	-0.6	0.5	0.0
Locomotion velocity, hab. session 1	0.2	0.2	0.4	-0.6	0.5	0.1
Time in familiar zone, hab. session 2	0.2	0.2	0.3	-0.5	0.5	-0.2
Time in novel zone, hab. session 2	0.1	0.1	0.1	-0.1	0.2	-0.4
Total zone transitions, hab. session 2	1.3	1.7	2.8	-1.7	1.5	0.2
Total locomotion distance, hab. session 2	0.9	1.2	1.7	-1.3	0.9	1.0
Locomotion velocity, hab. session 2	0.8	1.0	1.3	-1.1	0.7	1.2
Novel to familiar place preference ratio	3.0	3.3	4.5	2.1	-2.1	1.0
Novelty place preference	2.9	3.2	4.3	2.1	-2.1	0.9
Time in novel zone, NPP test	2.3	2.4	3.4	1.8	-1.8	0.9
Total zone transitions, NPP test	2.1	3.0	5.1	-2.3	2.0	0.2
Total locomotion distance, NPP test	1.8	2.4	4.3	-2.1	1.5	0.8
Locomotion velocity, NPP test	1.1	1.5	2.6	-1.6	1.1	0.9
Intraocular pressure	0.6	0.9	2.2	0.3	-0.7	1.5
Delta distance traveled before/after self-admin	0.5	0.6	1.1	-1.0	0.8	0.2
Delta ambulatory time before/after self-admin	1.3	1.6	2.7	-1.7	1.4	-0.0
Parametrial fat weight	0.4	0.9	2.3	0.3	-0.5	1.5
Pavlov. Cond. lever latency	1.6	2.1	3.3	-1.8	1.7	-0.3
Pavlov. Cond. magazine entry latency	3.2	4.1	5.9	2.4	-2.3	0.9
Pavlov. Cond. change in total contacts	1.3	1.3	2.2	1.5	-1.3	-0.4
Pavlov. Cond. index score	3.3	4.1	5.3	2.3	-2.3	1.3
Pavlov. Cond. latency score	3.0	3.7	5.2	2.3	-2.2	1.1
Pavlov. Cond. lever contacts	0.9	1.0	1.5	1.2	-1.2	0.5
Pavlov. Cond. magazine entry number	4.3	5.4	8.4	-2.9	2.7	-0.7
Pavlov. Cond. intertrial magazine entries	0.4	0.4	1.0	-0.5	0.2	1.0
Pavlov. Cond. lever-magazine prob. diff.	3.1	3.8	5.1	2.3	-2.2	1.2
Pavlov. Cond. response bias	3.1	3.8	6.1	2.5	-2.3	0.6
Pavlov. Cond. lever latency	0.7	0.9	2.6	0.3	0.2	-1.6
Pavlov. Cond. magazine entry latency	2.0	2.4	3.4	-1.8	1.8	-0.8
Pavlov. Cond. change in total contacts	0.3	0.5	0.9	-0.9	0.8	0.2
Pavlov. Cond. index score	0.3	0.4	0.8	-0.9	0.7	0.2
Pavlov. Cond. latency score	0.4	0.6	0.9	-1.0	0.8	0.3
Pavlov. Cond. lever contacts	0.6	0.8	2.2	-0.4	-0.0	1.5
Pavlov. Cond. magazine entry number	1.4	1.7	2.4	1.5	-1.5	0.6
Pavlov. Cond. intertrial magazine entries	0.8	1.3	2.3	0.6	-1.1	1.5
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.6	1.0	-1.0	0.9	0.0
Pavlov. Cond. response bias	0.3	0.4	0.6	-0.8	0.5	0.5
Time in closed arm before self-admin	0.3	0.4	0.9	0.6	-0.2	-0.9
Time in closed arm after self-admin	0.3	0.4	1.0	0.2	0.1	-1.0
Time in open arm before self-admin	0.7	0.8	1.1	-1.0	0.9	0.7
Time in open arm after self-admin	0.2	0.3	0.5	-0.7	0.5	0.3
Bone: periosteal estimation	0.7	1.4	1.8	1.3	-1.1	1.2
Bone: periosteal perimeter	3.3	5.7	9.4	3.1	-2.6	1.0
Bone: post-yield work	0.1	0.1	0.3	-0.5	0.4	0.0
Progressive ratio test 1 active lever presses	0.2	0.3	0.6	0.4	-0.4	0.8
Progressive ratio test 1 breakpoint	0.3	0.4	0.7	0.5	-0.5	0.9
Progressive ratio test 1 inactive lever presses	1.4	2.1	5.0	0.6	-1.0	2.2
Progressive ratio test 2 active lever presses	0.2	0.3	0.5	0.2	-0.4	0.7
Progressive ratio test 2 breakpoint	0.2	0.3	0.6	0.3	-0.5	0.7
Progressive ratio test 2 inactive lever presses	0.3	0.4	0.6	0.7	-0.8	0.3
Incentive Sensitization - Responses	0.2	0.4	0.8	0.2	-0.5	0.9
Incentive Sensitization - Breakpoint	0.2	0.3	0.6	0.2	-0.5	0.8
Sum of active levers in priming session hrs 5-6	1.9	1.8	2.8	1.6	-1.7	0.2
Progressive ratio	0.5	0.8	1.0	-0.7	0.9	-1.0
Food seeking constrained by brief footshock	0.2	0.3	0.4	0.7	-0.4	-0.4
Seeking ratio, punishment vs. effort	0.1	0.1	0.3	0.1	-0.2	0.6
Retroperitoneal fat weight	1.5	6.6	13.7	1.5	-1.9	3.7
Reaction time number correct	1.6	3.1	5.0	-2.2	1.8	1.1
Reaction time mean minus median	0.1	0.2	0.3	0.5	-0.4	-0.5
Reaction time mean minus median AUC	0.0	0.0	0.1	0.2	-0.2	-0.2
Reaction time num false alarms	0.1	0.1	0.1	-0.3	0.3	-0.2
Reaction time num false alarms AUC	0.3	0.5	0.6	-0.8	0.8	-0.5
Reaction time trials correct on left	1.6	3.1	5.0	-2.2	1.8	1.1
Reaction time trials on left	1.7	3.3	5.2	-2.3	1.8	1.2
Reaction time mean	0.1	0.2	0.5	0.2	-0.4	0.7
Reaction time mean AUC	0.1	0.2	0.5	-0.2	0.0	0.7
Median of all reaction times	0.2	0.3	0.7	0.0	-0.3	0.9
Reaction time omissions	0.1	0.1	0.2	-0.2	0.1	0.5
Reaction time false alarm rate	0.3	0.4	0.8	0.4	-0.3	-0.9
Reaction time premature initiation rate	0.7	0.9	1.1	-0.9	0.9	-1.0
Reaction time premature initiations	1.3	2.2	3.9	-2.0	1.7	-0.3
Std. dev. reaction times	0.1	0.2	0.2	-0.5	0.4	-0.4
Reaction time trials completed	1.7	3.3	5.2	-2.3	1.8	1.2
Reaction time trials AUC	1.7	3.2	5.0	-2.2	1.8	1.2
Run reversals in cocaine runway, females	1.0	1.0	1.8	-1.3	1.0	-0.3
Run reversals in cocaine runway, males	2.4	2.4	3.4	1.8	-1.8	0.7
Latency to leave start box in cocaine runway	0.4	0.5	0.7	-0.8	0.8	-0.2
Latency to leave start box in cocaine runway, F	1.6	1.8	2.9	-1.7	1.6	0.2
Latency to leave start box in cocaine runway, M	0.3	0.3	0.4	0.6	-0.5	-0.3
Std. dev. time between licks in bursts	1.3	1.7	2.5	-1.6	1.2	1.2
Total sessions with >9 infusions	0.2	0.3	0.5	-0.4	0.7	-0.3
Short access day 1 total inactive lever presses	0.4	0.5	0.8	-0.8	0.9	-0.2
Short access day 10 total inactive lever presses	0.9	2.1	3.6	1.0	-1.3	1.9
Short access day 1 total infusions	1.2	1.6	1.9	-1.1	1.4	-1.3
Short access day 10 total infusions	1.3	1.6	1.7	1.3	-1.2	1.3
Short access total infusions	0.0	0.0	0.0	-0.0	0.1	-0.0
Short access day 1 locomotion	0.2	0.2	0.6	0.2	0.1	-0.8
Short access day 10 total locomotion	0.4	0.7	1.0	1.0	-0.6	-0.9
Short access total locomotion	0.3	0.4	0.7	0.8	-0.5	-0.5
One hour access (0.3 mA shock)	0.2	0.2	0.5	0.1	-0.2	0.7
Compulsive drug intake	0.3	0.3	0.8	-0.4	0.1	0.9
One hour access (shock baseline)	0.1	0.1	0.2	-0.1	0.1	0.5
Social response proportion	0.3	0.4	0.6	-0.6	0.8	-0.3
Social responses	0.5	0.6	1.2	-0.6	1.1	-0.5
Social time	0.3	0.4	0.6	-0.6	0.8	-0.5
Soleus weight	1.0	3.0	4.4	1.5	-1.5	2.1
Bone: stiffness	0.0	0.1	0.1	0.4	-0.2	-0.0
Tibialis anterior weight	0.1	0.2	0.4	-0.2	0.4	0.6
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	-0.4	0.4	-0.1
Time to tail flick, vehicle, after self-admin	2.2	2.9	3.4	-1.4	1.8	-1.8
Time to tail flick, test, before self-admin	0.0	0.0	0.0	0.0	0.1	-0.1
Time to tail flick, test, after self-admin	0.6	0.7	1.9	-0.0	0.3	-1.4
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.7	-0.7	0.8	-0.3
Delta time to tail flick, test, before/after SA	0.6	0.6	1.9	0.2	0.0	-1.4
Tibia length	7.3	20.0	27.4	5.2	-4.9	3.0
Ambulatory time before self-admin	1.8	2.8	3.8	1.9	-1.9	1.0
Ambulatory time after self-admin	0.4	0.4	0.9	0.3	-0.5	1.0
Bone: tissue strength	0.6	0.6	1.4	0.6	-0.5	1.2
Total heroin consumption	0.9	1.0	1.4	1.0	-0.7	-1.2
Bone: trabecular number	0.1	0.1	0.2	0.1	-0.3	0.4
Bone: trabecular spacing	1.2	1.5	2.4	-1.6	1.3	0.7
Bone: trabecular thickness	2.0	2.5	3.7	1.9	-1.9	0.4
Bone: trabecular tissue density	0.6	0.9	1.1	-0.8	1.0	-0.9
Water consumed over 24 hours	0.3	0.4	1.0	1.0	-0.5	-0.1
Number of responses in last shaping day	0.2	0.2	0.4	-0.2	0.4	-0.6