Hub : Genes

Ogdh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ogdh 0.11 0.06 6.5e-10 0.12 0.11 0.11 0.11 6.3e-11 2.1e-10 1.7e-10 2.5e-10
2 NAcc isoform ratio XM_039092218.2 0.02 0.01 4.2e-05 0.03 0.03 0.03 0.03 5.3e-05 3.6e-05 2.9e-05 6.2e-05
3 Liver mRNA stability Ogdh 0.13 0.08 1.3e-13 0.06 0.11 0.11 0.11 1.6e-07 1.2e-12 4.3e-12 8.2e-12
4 NAcc isoform ratio XM_006251446.5 0.01 0.01 1.0e-02 0 -0 0 0 8.5e-02 4.2e-01 3.4e-01 3.5e-01
5 NAcc intron excision ratio chr14_85387865_85403711 0.02 0.01 2.1e-04 0.03 0.02 0.02 0.02 6.1e-05 4.6e-04 1.1e-03 2.3e-04
6 NAcc intron excision ratio chr14_85394599_85403711 0.01 0.01 2.8e-03 0.01 0.01 0.01 0.01 4.5e-03 7.2e-03 3.9e-02 9.9e-03
7 RMTg mRNA stability Ogdh 0.17 0.1 2.4e-04 0.11 0.13 0.1 0.12 9.1e-04 2.3e-04 1.3e-03 5.8e-04
8 Brain intron excision ratio chr14_85387865_85394555 0.02 0.02 8.7e-03 0.01 0.02 0.01 0.01 2.2e-02 6.4e-03 1.5e-02 1.2e-02
9 IC gene expression Ogdh 0.05 0.04 3.5e-03 0.02 0.05 0.04 0.03 3.3e-02 3.5e-03 1.2e-02 2.8e-02
10 pVTA gene expression Ogdh 0.06 0.04 2.5e-04 0.04 0.05 0.04 0.04 2.9e-04 3.8e-05 2.3e-04 2.1e-04
11 NAcc gene expression Ogdh 0.07 0.04 1.1e-09 0.06 0.06 0.06 0.06 3.1e-09 3.7e-10 1.2e-09 1.5e-09
12 IL gene expression Ogdh 0.33 0.19 5.2e-03 0.03 0.09 0.1 0.06 5.9e-02 3.7e-03 2.6e-03 1.7e-02
13 Eye intron excision ratio chr14_85384144_85387550 0.25 0.15 8.2e-03 0.2 0.13 0.11 0.14 5.4e-04 4.6e-03 8.2e-03 4.0e-03
14 PL gene expression Ogdh 0.08 0.05 2.7e-06 0.05 0.05 0.06 0.06 4.5e-06 2.9e-06 8.1e-07 1.1e-06
15 Liver gene expression Ogdh 0.13 0.07 4.0e-10 0.05 0.06 0.06 0.06 1.3e-06 1.6e-07 3.2e-07 3.4e-07
16 OFC gene expression Ogdh 0.29 0.15 2.3e-03 0 0.05 0.05 0.03 2.6e-01 2.2e-02 2.8e-02 6.5e-02
17 Brain gene expression Ogdh 0.24 0.1 1.1e-14 0.04 0.14 0.13 0.13 1.1e-04 3.5e-13 1.7e-12 2.4e-12
18 PL intron excision ratio chr14_85394599_85403711 0.03 0.03 8.9e-03 0.01 0.01 0.02 0.01 1.4e-02 9.4e-03 4.1e-03 9.0e-03
19 Adipose gene expression Ogdh 0.04 0.03 8.1e-03 0.04 0.01 0.03 0.03 8.0e-05 4.1e-02 2.5e-04 3.1e-04
20 Brain intron excision ratio chr14_85394599_85403711 0.04 0.03 4.1e-03 0.01 0.02 0.02 0.02 2.3e-02 2.9e-03 2.4e-03 4.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.10.20.40.20.30.10.1-0.10.30.20.20.30.30.4-0.30.30.30.30.30.00.1-0.2
Area under the delay curve2.83.37.7-1.8-2.4-2.12.82.8-2.6-1.9-2.2-2.5-0.7-0.6-0.21.8-1.0-0.0-0.00.3-2.11.2-2.0
BMI with tail0.10.51.1-1.1-0.8-0.90.80.8-0.8-0.9-0.8-0.8-0.7-0.7-0.80.2-0.8-0.6-0.6-0.7-0.3-0.10.3
BMI without tail0.31.02.2-1.5-1.3-1.11.31.3-1.3-0.9-1.3-1.1-0.9-0.8-0.51.0-0.9-0.4-0.5-0.5-0.90.1-0.3
Body weight1.35.711.0-2.8-3.2-3.03.33.3-3.2-2.7-2.9-3.0-1.9-1.8-1.22.7-2.0-1.1-1.2-1.0-2.30.4-1.6
Weight adjusted by age0.10.20.5-0.2-0.5-0.60.60.6-0.5-0.5-0.6-0.7-0.1-0.1-0.00.6-0.30.00.00.1-0.60.3-0.5
Bone surface0.10.10.2-0.1-0.3-0.30.50.5-0.4-0.4-0.2-0.3-0.5-0.5-0.30.3-0.3-0.5-0.5-0.4-0.2-0.3-0.3
Bone volume0.10.20.5-0.3-0.3-0.40.70.7-0.6-0.5-0.3-0.4-0.5-0.4-0.30.2-0.4-0.4-0.4-0.4-0.2-0.3-0.3
Breakpoint value in progressive ratio session0.20.20.6-0.4-0.4-0.70.30.3-0.3-0.7-0.6-0.8-0.4-0.5-0.30.4-0.7-0.4-0.4-0.4-0.30.0-0.1
Number of licking bursts1.72.74.9-1.6-2.1-2.12.22.2-2.0-2.1-1.8-2.2-1.3-1.2-1.51.9-1.4-1.0-1.0-0.6-1.5-0.6-1.1
Context. condit. distance diff. score1.72.14.21.91.81.7-1.7-1.71.81.52.01.81.31.20.4-1.71.40.60.70.71.7-0.41.0
Locomotion velocity, session 10.30.41.00.30.80.7-1.0-1.00.80.60.60.8-0.00.00.3-0.80.2-0.1-0.1-0.20.6-0.40.6
Locomotion distance, session 11.41.74.51.20.20.6-0.2-0.20.01.00.10.11.71.72.10.21.72.02.02.0-1.02.0-1.4
Locomotion velocity, session 20.70.81.5-0.00.90.5-1.2-1.21.20.20.70.9-0.8-0.8-0.3-0.9-0.5-1.1-1.1-1.20.9-1.11.1
Locomotion distance, session 20.81.22.01.21.11.3-1.2-1.21.01.40.81.21.11.21.4-0.71.21.21.11.00.30.70.0
Locomotion velocity, session 31.31.53.11.41.11.3-1.2-1.21.21.41.31.21.41.41.5-0.41.81.21.21.2-0.20.9-0.3
Locomotion distance, session 30.40.41.2-1.0-0.9-0.80.30.3-0.4-0.8-0.7-0.7-0.7-0.7-0.51.1-0.6-0.6-0.6-0.6-0.9-0.0-0.2
Stereotopy head waving bouts, day 30.50.61.30.90.81.0-0.8-0.80.81.10.60.90.70.71.1-0.50.80.80.70.6-0.00.6-0.1
Stereotopy head waving duration, day 31.92.33.81.82.01.9-1.8-1.81.81.91.61.91.31.31.4-1.71.41.01.00.91.10.20.7
Locomotion velocity, session 70.20.20.4-0.6-0.3-0.50.30.3-0.2-0.5-0.4-0.4-0.6-0.5-0.50.1-0.5-0.5-0.5-0.50.0-0.50.1
Locomotion distance, session 70.10.20.80.10.30.1-0.2-0.20.40.00.40.20.10.1-0.6-0.5-0.1-0.2-0.1-0.00.9-0.70.7
Stereotopy head waving bouts, day 70.10.10.40.40.20.3-0.4-0.40.20.30.50.30.20.20.6-0.10.60.10.10.2-0.50.3-0.5
Stereotopy head waving duration, day 70.20.31.20.40.10.3-0.2-0.2-0.10.40.20.20.40.41.10.20.70.50.50.5-0.90.8-0.9
Locomotion velocity, session 80.91.02.31.31.31.2-1.5-1.51.41.01.51.40.50.40.3-1.00.8-0.10.00.10.9-0.60.7
Locomotion distance, session 84.36.29.83.13.03.1-3.0-3.02.93.03.03.12.32.31.7-2.62.51.61.71.52.20.21.3
Degree of sensitization distance2.12.25.41.82.01.7-1.4-1.41.61.51.91.71.21.10.2-2.21.00.50.60.72.3-1.01.5
Degree of sensitization stereotypy0.10.10.50.0-0.2-0.10.10.1-0.3-0.10.0-0.1-0.0-0.00.40.40.2-0.0-0.00.1-0.70.3-0.6
Conditioned locomotion1.11.33.71.10.10.60.10.1-0.20.90.10.21.61.71.50.31.41.91.91.9-0.81.4-1.1
Cocaine response after cond. corrected1.01.32.1-1.2-1.4-1.41.31.3-1.4-1.4-1.2-1.5-0.8-0.8-0.51.2-0.5-0.7-0.6-0.4-1.50.2-1.4
Cocaine response after cond. not corrected1.41.63.0-1.4-1.6-1.71.61.6-1.6-1.6-1.4-1.7-0.8-0.7-0.41.4-0.5-0.5-0.5-0.2-1.70.4-1.6
Cocaine response before conditioning0.20.20.60.50.30.4-0.0-0.00.10.50.30.20.80.80.5-0.20.60.70.70.70.00.4-0.0
Saline control response0.20.20.60.30.60.5-0.8-0.80.70.50.60.70.10.10.3-0.40.4-0.1-0.1-0.10.1-0.30.3
Bone: connectivity density0.10.20.60.70.60.5-0.3-0.30.40.50.50.50.40.30.3-0.70.40.20.20.20.5-0.00.2
Bone: cortical apparent density0.30.40.8-0.9-0.7-0.70.40.4-0.3-0.8-0.7-0.7-0.8-0.8-0.40.7-0.7-0.6-0.7-0.7-0.6-0.0-0.3
Bone: cortical area1.52.44.5-1.6-2.0-1.82.02.0-2.1-1.6-1.9-1.9-1.0-1.0-0.32.0-0.9-0.5-0.5-0.5-2.00.8-1.7
Bone: cortical porosity0.10.10.6-0.00.30.1-0.2-0.2-0.00.00.00.1-0.1-0.1-0.2-0.8-0.3-0.1-0.1-0.10.6-0.40.5
Bone: cortical porosity0.10.20.60.50.40.3-0.1-0.1-0.10.40.30.20.50.50.3-0.80.40.50.50.50.50.00.2
Bone: cortical thickness1.11.93.7-1.4-1.8-1.61.91.9-1.8-1.4-1.7-1.7-0.7-0.7-0.11.7-0.7-0.2-0.2-0.2-1.71.0-1.6
Bone: cortical thickness1.01.23.31.00.10.41.21.2-0.80.60.40.11.51.51.2-0.21.61.51.61.8-0.41.1-1.3
Bone: cortical tissue density0.30.50.9-1.0-0.7-0.80.40.4-0.3-0.8-0.7-0.7-0.9-0.9-0.50.7-0.8-0.8-0.8-0.8-0.5-0.1-0.2
Condit. Reinf. active minus inactive responses1.31.52.8-1.7-0.9-1.20.80.8-0.9-1.3-1.0-0.9-1.7-1.7-1.40.6-1.6-1.5-1.6-1.6-0.4-1.30.3
Condit. Reinf. active-inactive response ratio1.51.64.8-0.60.6-0.0-0.8-0.80.7-0.50.60.4-1.3-1.4-1.6-1.1-1.2-1.8-1.8-1.81.3-2.21.9
Condit. Reinf. active responses0.60.81.6-1.3-0.9-0.90.80.8-1.0-0.9-0.9-0.8-1.1-1.0-0.80.8-1.0-0.9-0.9-0.8-0.7-0.8-0.1
Condit. Reinf. inactive responses0.70.82.1-0.6-1.1-0.81.21.2-1.2-0.6-1.0-1.00.10.10.31.4-0.00.50.50.6-1.40.7-1.4
Incentive salience index mean1.62.03.2-1.8-1.6-1.61.61.6-1.8-1.6-1.6-1.5-1.5-1.5-1.01.5-1.5-1.1-1.1-1.1-1.3-0.5-0.7
Condit. Reinf. lever presses1.21.75.0-0.9-1.6-1.11.61.6-1.9-0.8-1.5-1.4-0.10.00.52.0-0.00.60.50.6-2.21.2-2.0
Condit. Reinf. active minus inactive responses0.20.20.50.50.40.6-0.4-0.40.10.60.60.50.60.60.5-0.40.70.50.50.60.30.20.0
Condit. Reinf. active-inactive response ratio0.10.10.3-0.3-0.5-0.30.20.2-0.5-0.2-0.3-0.40.10.10.20.40.10.20.30.3-0.50.4-0.5
Condit. Reinf. active responses0.30.50.90.70.70.9-0.7-0.70.51.00.80.90.70.70.7-0.60.80.60.60.50.50.20.3
Condit. Reinf. inactive responses0.70.92.01.11.41.3-1.0-1.01.11.21.31.40.70.60.5-1.30.70.30.30.21.2-0.30.9
Condit. Reinf. lever presses0.20.20.60.70.30.50.10.1-0.20.50.60.40.70.70.5-0.30.80.50.60.70.10.3-0.3
Condit. Reinf. lever reinforcers received0.20.30.60.60.50.7-0.3-0.30.20.70.60.70.60.60.6-0.50.70.60.60.50.40.30.0
Conditioned reinforcement - actives0.00.10.2-0.4-0.1-0.00.40.4-0.40.0-0.30.0-0.3-0.30.20.4-0.2-0.1-0.1-0.3-0.20.2-0.4
Conditioned reinforcement - inactives0.30.41.2-0.9-0.6-0.51.01.0-1.0-0.5-0.7-0.5-0.6-0.5-0.20.8-0.4-0.3-0.4-0.4-0.50.0-1.1
Conditioned locomotion0.60.81.9-1.1-0.9-0.81.21.2-1.0-0.6-1.3-0.6-1.0-0.90.21.4-0.8-0.3-0.4-0.7-1.20.5-0.6
Patch foraging indifference point 0 sec2.34.39.9-2.5-1.7-2.31.41.4-1.1-2.7-1.3-1.9-2.4-2.5-3.11.0-2.5-2.7-2.6-2.30.0-2.10.9
Patch foraging indifference point AUC0.20.31.7-0.4-0.0-0.10.10.1-0.1-0.2-0.10.1-0.6-0.6-0.9-0.0-0.5-0.6-0.6-0.60.4-1.30.5
Delay disc. indifference point, 0s delay1.31.44.5-1.0-1.4-1.62.12.1-1.3-1.6-1.0-1.9-0.1-0.2-0.91.1-0.3-0.2-0.10.3-0.90.5-1.3
Delay disc. indifference point, 16s delay1.21.32.4-1.3-1.6-1.31.51.5-1.5-1.2-1.5-1.4-1.0-1.0-0.40.9-1.2-0.5-0.6-0.6-1.20.3-0.8
Delay disc. indifference point, 2s delay2.52.87.0-1.3-1.8-1.92.62.6-2.5-1.6-1.8-2.40.00.00.11.8-0.30.50.50.9-2.01.5-2.3
Delay disc. indifference point, 24s delay1.01.23.1-1.2-1.7-1.41.41.4-1.5-1.3-1.4-1.5-0.8-0.7-0.70.7-1.1-0.4-0.4-0.3-0.90.2-0.7
Delay disc. indifference point, 4s delay3.43.68.2-1.7-2.1-2.22.92.9-2.7-1.9-2.3-2.5-0.5-0.40.22.3-0.70.20.20.5-2.51.5-2.5
Delay disc. indifference point, 8s delay1.21.43.3-0.8-1.7-1.01.51.5-1.7-0.7-1.4-1.3-0.00.10.51.3-0.10.60.60.7-1.61.4-1.8
Indifference point function ln k0.10.20.60.0-0.3-0.10.50.5-0.50.1-0.4-0.30.50.50.80.20.30.80.70.7-0.60.7-0.6
Indifference point function log k0.10.20.60.0-0.3-0.10.50.5-0.50.1-0.4-0.30.50.50.80.20.30.80.70.7-0.60.7-0.6
Patch foraging total patch changes 0 sec2.54.811.1-2.6-1.7-2.41.51.5-1.2-2.7-1.3-1.9-2.6-2.6-3.30.9-2.7-2.9-2.8-2.50.1-2.41.0
Patch foraging total patch changes 12 sec2.12.88.5-1.7-0.9-1.50.80.8-0.5-1.9-0.7-1.1-2.0-2.0-2.90.2-2.0-2.3-2.2-2.10.7-2.21.3
Patch foraging total patch changes 18 sec2.43.79.1-2.2-1.4-1.91.21.2-0.9-2.3-0.9-1.4-2.4-2.4-3.00.9-2.3-2.8-2.7-2.40.3-1.91.1
Patch foraging total patch changes 24 sec0.81.44.30.11.00.5-0.8-0.81.20.01.40.9-0.5-0.6-1.7-1.2-0.3-1.4-1.2-1.11.9-1.82.1
Patch foraging total patch changes 6 sec2.74.18.6-2.4-1.5-2.11.31.3-1.0-2.4-1.3-1.7-2.6-2.6-2.90.9-2.6-2.7-2.6-2.50.0-2.20.9
Patch foraging time to switch 0 sec0.30.61.40.80.60.7-0.5-0.50.60.80.60.51.01.01.1-0.31.00.90.90.9-0.11.2-0.3
Patch foraging water rate 0 sec1.43.05.5-2.1-1.4-1.71.01.0-1.2-1.9-1.4-1.3-2.3-2.3-2.11.0-2.3-2.2-2.2-2.2-0.3-1.70.6
Patch foraging water rate 12 sec0.10.20.6-0.5-0.5-0.40.40.4-0.7-0.4-0.3-0.3-0.5-0.5-0.00.6-0.5-0.4-0.4-0.4-0.40.6-0.1
Patch foraging water rate 18 sec0.71.24.60.3-0.5-0.10.50.5-0.70.3-0.6-0.51.11.11.40.90.91.61.51.5-1.22.1-1.4
Patch foraging water rate 24 sec0.10.10.5-0.4-0.10.1-0.0-0.0-0.20.1-0.20.2-0.4-0.30.40.4-0.2-0.1-0.2-0.4-0.40.7-0.0
Patch foraging water rate 6 sec0.40.51.8-0.4-0.9-0.40.70.7-1.2-0.1-1.0-0.5-0.1-0.00.61.3-0.10.50.40.3-1.20.7-1.1
Seeking ratio, delayed vs. immediate footshock0.60.73.10.50.10.5-0.0-0.0-0.10.9-0.30.40.70.81.80.50.81.31.20.9-1.11.2-1.0
Distance traveled before self-admin0.10.10.4-0.1-0.3-0.2-0.0-0.0-0.2-0.3-0.1-0.1-0.4-0.4-0.60.50.0-0.5-0.5-0.4-0.0-0.6-0.6
Distance traveled after self-admin0.20.21.7-0.0-0.4-0.20.30.3-0.4-0.1-0.4-0.40.20.20.40.80.40.40.40.4-0.60.6-1.3
Extensor digitorum longus weight2.18.115.5-3.9-3.3-3.43.13.1-2.9-3.3-3.4-3.1-3.2-3.1-2.22.6-3.2-2.3-2.5-2.5-2.0-0.5-1.1
Bone: elastic displacement0.50.61.50.91.10.9-1.1-1.11.20.80.80.90.60.50.6-1.00.60.40.30.20.60.10.6
Bone: elastic work0.10.10.40.0-0.3-0.30.30.3-0.3-0.2-0.5-0.50.10.10.40.30.00.30.30.3-0.50.6-0.6
Bone: endosteal estimation0.00.10.50.0-0.4-0.20.30.3-0.7-0.2-0.2-0.3-0.1-0.1-0.10.5-0.0-0.1-0.10.0-0.3-0.0-0.4
Bone: endosteal perimeter0.61.33.3-0.9-1.6-1.11.51.5-1.8-0.9-1.2-1.2-0.3-0.20.21.8-0.20.20.20.3-1.61.0-1.6
Epididymis fat weight0.41.22.0-1.3-1.4-1.41.41.4-1.3-1.3-1.3-1.4-1.0-1.0-0.51.3-0.9-0.7-0.7-0.7-1.10.3-0.7
Delta time in closed arm before/after self-admin8.98.312.73.32.93.3-2.7-2.72.83.52.62.83.43.43.6-2.23.53.13.12.90.92.2-0.3
Delta time in open arm before/after self-admin6.06.09.6-2.5-2.7-2.72.02.0-2.3-2.9-2.2-2.3-3.0-3.0-3.12.2-2.7-2.8-2.8-2.7-0.9-1.8-0.4
Diff in mean of infusions in LGA sessions0.20.31.10.30.20.0-0.1-0.10.40.2-0.1-0.20.60.61.0-0.00.30.70.70.7-0.51.1-0.3
Delay discount exponential model param2.93.27.61.82.42.1-2.8-2.82.71.92.22.50.60.60.3-1.71.00.00.0-0.32.1-1.22.0
Extinction: sum of active levers before priming0.10.10.4-0.4-0.2-0.1-0.1-0.1-0.1-0.1-0.30.0-0.5-0.5-0.00.3-0.6-0.3-0.4-0.6-0.1-0.10.2
Active lever presses in extinction session 60.70.72.40.50.30.3-0.3-0.30.30.50.1-0.01.11.11.5-0.20.91.21.11.1-0.51.5-0.7
Bone: final force0.20.40.9-0.7-0.4-0.50.30.3-0.5-0.6-0.5-0.3-1.0-0.9-0.70.2-0.8-0.8-0.9-0.9-0.0-0.50.2
Bone: final moment0.30.51.1-0.9-0.5-0.70.40.4-0.6-0.8-0.7-0.5-1.1-1.0-0.80.4-1.0-0.9-0.9-1.0-0.1-0.50.2
Food consumed during 24 hour testing period1.31.83.9-1.8-0.9-1.20.60.6-0.6-1.4-1.0-0.8-2.0-2.0-1.40.4-1.8-1.8-1.9-1.9-0.0-1.00.6
Glucose12.920.346.4-5.5-2.3-3.51.01.0-1.4-4.2-2.7-2.1-6.6-6.6-5.60.9-6.3-6.4-6.6-6.81.1-4.93.1
Heart weight1.01.53.7-0.9-0.1-0.6-0.3-0.30.2-0.9-0.0-0.2-1.5-1.6-1.6-0.5-1.5-1.9-1.9-1.90.7-1.81.8
Delay discount hyperbolic model param3.13.58.21.82.42.2-2.9-2.92.81.92.32.50.60.50.1-1.90.9-0.1-0.1-0.42.2-1.32.2
Intermittent access intake day 1-15 change0.81.63.9-1.1-0.9-1.10.90.9-1.0-1.2-0.9-0.7-1.8-1.7-2.00.9-1.4-1.7-1.7-1.7-0.0-1.70.3
Intermittent access intake escalation0.71.53.7-1.1-0.9-1.10.90.9-1.0-1.2-0.9-0.7-1.6-1.6-1.90.9-1.3-1.5-1.5-1.5-0.1-1.90.1
Intermittent access intake escalation 20.80.93.9-0.5-0.4-0.50.30.3-0.3-0.7-0.2-0.2-1.2-1.2-1.90.5-0.7-1.3-1.3-1.20.5-2.0-0.0
Intermitt. access day 1 inactive lever presses0.10.41.20.10.20.60.10.1-0.10.70.30.40.80.81.0-0.00.90.90.90.8-0.01.1-0.9
Intermitt. access day 15 inactive lever presses1.32.74.9-2.2-1.6-1.51.61.6-1.6-1.6-1.5-1.2-2.1-2.0-1.81.4-1.9-1.8-1.8-1.8-0.6-1.3-0.1
Intermitt. access escalation Index0.91.34.3-0.2-0.0-0.50.00.00.0-0.80.0-0.1-1.3-1.3-1.9-0.3-1.6-1.6-1.5-1.50.8-1.92.1
Intermittent access day 1 total infusions0.40.62.40.1-0.10.10.60.6-0.30.2-0.3-0.30.70.81.10.20.71.11.01.1-0.71.2-1.5
Intermittent access day 15 total infusions0.91.42.0-1.2-1.1-1.31.41.4-1.2-1.3-1.3-1.2-1.4-1.4-1.31.1-1.3-1.1-1.1-1.1-0.6-1.0-0.7
Intermittent access terminal intake (last 3 days)0.71.02.5-0.8-0.6-0.80.90.9-0.6-1.0-0.7-0.6-1.3-1.2-1.60.6-1.0-1.2-1.2-1.20.0-1.6-0.2
Intermittent access total infusions0.40.51.0-0.6-0.7-0.71.01.0-0.7-0.8-0.9-0.8-0.7-0.7-0.50.6-0.8-0.4-0.5-0.5-0.5-0.3-0.6
Intermittent access day 1 locomotion1.41.77.50.70.61.1-0.5-0.50.51.40.10.71.31.42.7-0.11.21.91.71.5-0.82.3-1.4
Intermittent access day 15 total locomotion0.30.61.3-0.8-0.9-0.70.80.8-0.6-0.6-1.1-0.8-0.6-0.60.41.1-0.6-0.1-0.2-0.4-1.10.8-0.8
Intermittent access total locomotion0.50.61.4-0.7-0.9-0.60.80.8-0.7-0.5-1.2-0.8-0.5-0.40.61.1-0.70.2-0.0-0.1-1.21.0-1.0
Intermittent access standard deviation0.61.23.01.21.41.6-1.3-1.31.31.51.31.70.40.40.3-1.20.80.30.2-0.11.2-1.00.3
Left kidney weight0.20.83.5-0.0-0.9-0.40.70.7-0.9-0.1-0.9-0.70.50.51.01.10.31.00.90.9-1.21.9-1.4
Right kidney weight0.20.83.50.1-0.7-0.40.70.7-0.6-0.1-0.7-0.80.80.81.10.70.41.11.01.0-1.01.9-1.1
Cocaine induced anxiety1.82.55.2-1.7-1.6-1.81.11.1-1.3-1.9-1.8-1.6-2.0-2.0-1.51.4-2.3-1.6-1.7-1.8-1.0-0.70.3
Post-drug Anxiety2.12.23.9-1.7-1.7-1.91.51.5-1.3-2.0-1.7-1.9-1.6-1.6-1.41.2-2.0-1.3-1.4-1.3-1.0-0.30.1
Baseline Anxiety0.30.30.90.30.20.10.30.30.20.20.1-0.20.90.80.8-0.30.50.80.80.9-0.31.0-0.3
Tail length1.76.712.3-3.2-3.4-3.13.03.0-2.9-2.8-3.4-3.1-2.3-2.2-1.13.5-2.3-1.3-1.4-1.3-2.70.5-2.1
Length with tail1.77.513.3-3.1-3.6-3.33.43.4-3.4-3.1-3.5-3.4-2.3-2.2-1.23.6-2.3-1.4-1.4-1.3-2.70.4-2.2
Length without tail0.41.32.7-1.1-1.6-1.61.61.6-1.6-1.5-1.3-1.6-0.8-0.8-0.81.2-0.9-0.6-0.6-0.5-0.90.3-0.7
Times rat made contact with spout3.13.59.9-0.31.60.6-1.7-1.71.8-0.01.31.3-1.4-1.5-2.0-2.3-1.3-2.3-2.2-2.32.7-2.83.1
Lifetime Intake0.30.30.8-0.6-0.6-0.50.90.9-0.7-0.5-0.8-0.6-0.6-0.5-0.20.6-0.6-0.2-0.3-0.3-0.6-0.1-0.7
Liver weight, left0.60.92.01.10.71.0-0.6-0.60.51.20.60.81.31.30.9-0.61.01.41.41.30.50.7-0.1
Liver weight, right1.42.44.71.51.21.7-1.3-1.31.11.91.01.41.92.02.2-0.81.82.12.01.80.21.5-0.2
Locomotor activity0.91.43.9-1.0-0.3-0.70.20.2-0.0-1.0-0.2-0.3-1.5-1.5-2.00.1-1.5-1.8-1.7-1.60.6-1.91.1
Locomotor testing distance0.40.71.9-0.7-1.0-0.91.41.4-1.1-0.9-0.8-0.9-0.5-0.5-0.80.9-0.5-0.4-0.3-0.1-0.8-0.5-0.6
Locomotor testing rearing1.32.64.6-1.9-1.5-1.81.41.4-1.3-1.9-1.3-1.4-2.0-2.0-2.11.2-1.9-1.9-1.8-1.7-0.6-1.70.2
Locomotion in novel chamber2.43.16.62.61.81.6-1.6-1.62.01.52.11.22.42.31.2-1.72.21.61.72.01.30.80.2
Locomotion in novel chamber post-restriction1.72.74.52.01.61.9-1.3-1.31.32.01.71.62.12.01.9-1.42.11.81.81.80.81.1-0.1
Fecal boli incidents, locomotor time 10.20.20.80.30.60.5-0.9-0.90.50.60.30.50.30.30.7-0.40.30.40.40.20.00.40.3
Change in fecal boli incidents, locomotor task0.70.62.0-0.6-0.5-0.20.20.2-0.0-0.4-0.00.1-1.0-1.0-1.4-0.0-0.9-1.1-1.1-1.10.8-1.40.9
Time >=10cm from walls, locomotor time 10.20.20.50.70.30.4-0.5-0.50.70.40.60.40.60.5-0.1-0.60.70.30.30.30.4-0.00.0
Bouts of movement, locomotor time 11.01.24.2-0.7-0.7-0.91.41.4-1.0-1.2-0.2-0.7-1.1-1.1-2.10.1-0.8-1.4-1.3-1.00.9-1.40.1
Total resting periods, locomotor time 10.50.51.8-0.4-0.2-0.40.90.9-0.6-0.70.1-0.2-0.7-0.7-1.3-0.2-0.5-1.0-0.9-0.80.9-1.10.3
Rest time, locomotor task time 10.10.10.30.10.40.30.20.20.20.30.20.4-0.0-0.00.1-0.5-0.10.00.0-0.10.6-0.10.4
Distance moved, locomotor task time 10.20.30.8-0.6-0.7-0.50.10.1-0.7-0.4-0.8-0.5-0.4-0.40.30.9-0.5-0.0-0.2-0.3-0.90.4-0.4
Vertical activity count, locomotor time 10.00.10.2-0.3-0.4-0.30.00.0-0.4-0.3-0.3-0.3-0.3-0.3-0.30.4-0.4-0.3-0.3-0.3-0.4-0.2-0.0
Time >=10cm from walls, locomotor time 20.91.32.91.30.31.0-0.2-0.20.31.30.50.71.41.51.7-0.31.61.61.61.6-0.51.6-1.1
Bouts of movement, locomotor time 21.52.47.5-0.7-1.7-0.91.91.9-2.2-0.4-1.5-1.30.40.51.22.00.61.21.21.4-1.92.1-2.7
Total resting periods, locomotor time 21.22.05.8-0.9-1.8-1.02.02.0-2.2-0.7-1.5-1.40.10.20.71.90.30.80.81.0-1.71.6-2.4
Rest time, locomotor task time 20.30.41.50.00.50.3-0.5-0.50.40.10.40.5-0.4-0.4-0.5-0.8-0.5-0.6-0.6-0.80.9-0.91.2
Distance moved, locomotor task time 20.20.20.50.60.10.5-0.2-0.20.20.60.30.30.70.70.5-0.00.70.70.70.70.00.4-0.3
Vertical activity count, locomotor time 20.30.41.10.90.50.5-0.3-0.30.50.60.50.31.01.00.6-0.40.80.90.91.00.10.6-0.2
Light reinforcement 10.20.41.0-0.6-0.8-0.60.90.9-0.9-0.4-0.7-0.6-0.2-0.10.20.9-0.20.10.10.2-1.01.0-0.6
Light reinforcement 21.21.95.70.2-0.9-0.31.31.3-1.30.1-0.9-0.81.21.21.71.31.01.81.71.9-1.91.8-2.4
Bone: marrow area0.00.10.50.2-0.4-0.10.30.3-0.7-0.1-0.1-0.20.10.10.00.40.10.10.10.2-0.30.1-0.4
Bone: maximum diameter2.44.57.0-2.6-2.6-2.52.22.2-2.4-2.5-2.4-2.4-2.3-2.2-1.22.5-2.1-1.7-1.8-1.7-2.1-0.0-1.4
Bone: maximum force0.10.30.9-0.4-0.6-0.50.60.6-0.9-0.5-0.6-0.5-0.5-0.4-0.20.6-0.4-0.3-0.3-0.3-0.50.1-0.4
Bone: maximum moment0.20.41.0-0.6-0.8-0.70.80.8-1.0-0.7-0.7-0.7-0.6-0.5-0.30.7-0.5-0.4-0.4-0.3-0.60.1-0.5
Mean time between licks in bursts0.20.51.1-0.8-0.5-0.60.30.3-0.2-0.7-0.4-0.4-1.0-1.0-0.20.6-0.7-1.0-1.0-1.0-0.40.7-0.1
Mean num. licks in bursts2.64.09.01.12.72.1-2.9-2.92.71.72.32.50.10.1-0.0-3.00.3-0.6-0.6-0.92.9-1.22.9
Cd content in liver0.70.71.8-1.2-0.5-0.70.20.2-0.3-0.8-0.6-0.4-1.3-1.3-0.80.5-1.0-1.2-1.2-1.4-0.3-0.90.2
Co content in liver1.01.11.7-1.2-1.2-1.31.31.3-1.0-1.3-1.0-1.2-1.0-1.0-1.11.1-0.9-0.9-0.9-0.8-0.9-0.8-0.4
Cu content in liver0.20.30.9-0.6-0.2-0.3-0.2-0.2-0.0-0.4-0.2-0.0-0.8-0.8-0.4-0.0-0.7-0.8-0.9-0.90.1-0.40.6
Fe content in liver1.21.42.51.61.11.3-1.1-1.11.11.41.21.11.61.61.0-0.91.41.41.41.40.60.40.3
K content in liver1.91.84.9-0.6-1.8-1.31.61.6-1.5-0.9-1.7-1.6-0.00.00.82.0-0.20.60.50.6-1.92.2-1.9
Mg content in liver0.30.30.9-0.5-0.8-0.80.70.7-0.6-0.7-0.7-0.8-0.2-0.2-0.11.0-0.3-0.1-0.1-0.1-0.70.7-0.5
Mn content in liver0.30.31.7-0.4-0.7-0.40.40.4-0.4-0.1-0.8-0.50.00.10.61.00.10.50.40.4-1.30.3-1.0
Na content in liver2.02.14.0-1.4-1.9-1.82.02.0-2.0-1.8-1.6-1.9-1.2-1.1-1.01.5-1.2-0.9-0.8-0.6-1.20.4-1.0
Rb content in liver0.80.91.8-1.4-1.2-1.00.50.5-0.8-1.0-1.2-0.9-1.2-1.2-0.61.2-1.3-0.8-0.9-1.1-0.70.2-0.0
Se content in liver0.91.02.3-1.1-1.4-1.31.21.2-1.0-1.1-1.5-1.4-0.6-0.6-0.21.4-0.8-0.1-0.2-0.2-1.30.6-0.9
Sr content in liver3.32.85.7-1.8-2.0-2.41.91.9-1.9-2.4-2.0-2.4-1.5-1.5-1.31.5-1.6-1.2-1.2-1.0-1.20.3-0.8
Zn content in liver0.60.73.0-0.4-0.9-0.60.40.4-0.4-0.2-1.1-0.70.00.10.91.2-0.10.60.50.4-1.51.7-1.0
Bone: minimum diameter0.10.20.50.3-0.20.3-0.2-0.2-0.20.40.00.20.40.50.60.30.50.60.50.4-0.50.7-0.4
Time in familiar zone, hab. session 10.10.10.20.2-0.10.10.20.2-0.30.10.10.00.20.20.20.30.30.20.20.3-0.50.1-0.5
Time in novel zone, hab. session 10.30.31.0-0.60.2-0.2-0.4-0.40.5-0.3-0.1-0.1-0.6-0.6-0.5-0.4-0.7-0.7-0.7-0.80.6-0.51.0
Total zone transitions, hab. session 10.00.10.40.10.00.1-0.4-0.40.20.2-0.10.10.10.10.60.00.10.20.20.2-0.30.4-0.3
Total locomotion distance, hab. session 10.70.93.0-0.1-0.9-0.40.90.9-1.0-0.2-0.7-0.70.60.61.01.20.70.90.91.1-1.51.4-1.7
Locomotion velocity, hab. session 10.40.62.00.1-0.6-0.20.70.7-0.80.1-0.3-0.40.70.70.90.80.80.90.91.1-1.01.1-1.4
Time in familiar zone, hab. session 21.01.01.51.11.21.2-1.2-1.21.21.21.21.21.01.00.6-1.01.00.70.70.61.10.10.7
Time in novel zone, hab. session 21.31.42.7-1.4-0.9-1.30.70.7-0.7-1.4-1.2-1.1-1.6-1.6-1.10.6-1.6-1.4-1.5-1.5-0.4-0.80.2
Total zone transitions, hab. session 20.50.71.8-0.7-1.1-0.80.80.8-0.9-0.5-1.3-1.0-0.3-0.20.51.2-0.30.30.20.2-1.31.2-1.2
Total locomotion distance, hab. session 20.71.02.3-1.0-1.4-1.11.11.1-1.3-0.8-1.5-1.3-0.5-0.40.01.5-0.50.10.10.1-1.20.9-1.0
Locomotion velocity, hab. session 21.21.63.6-1.1-1.7-1.31.51.5-1.7-0.9-1.8-1.5-0.4-0.30.21.9-0.40.40.30.4-1.71.3-1.7
Novel to familiar place preference ratio0.20.20.5-0.5-0.1-0.2-0.0-0.0-0.0-0.3-0.2-0.1-0.7-0.7-0.3-0.0-0.6-0.7-0.7-0.70.1-0.40.1
Novelty place preference0.20.20.7-0.50.0-0.1-0.2-0.20.2-0.3-0.10.0-0.7-0.7-0.4-0.1-0.6-0.7-0.8-0.80.3-0.40.3
Time in novel zone, NPP test0.30.31.0-0.50.1-0.1-0.3-0.30.4-0.3-0.00.1-0.8-0.8-0.6-0.3-0.8-0.9-0.9-1.00.5-0.70.5
Total zone transitions, NPP test0.71.02.70.8-0.00.3-0.0-0.0-0.00.7-0.1-0.01.31.31.40.21.31.51.51.5-0.81.7-1.2
Total locomotion distance, NPP test0.91.23.30.4-0.6-0.10.90.9-0.90.2-0.6-0.61.11.21.30.91.11.51.61.6-1.21.8-1.6
Locomotion velocity, NPP test1.01.43.70.2-0.9-0.31.11.1-1.10.1-0.8-0.81.01.11.21.21.01.51.51.6-1.41.9-1.8
Intraocular pressure0.30.41.0-0.7-0.6-0.70.40.4-0.0-0.7-0.6-0.6-0.8-0.8-1.01.0-0.7-0.6-0.6-0.6-0.7-0.8-0.1
Delta distance traveled before/after self-admin0.80.81.80.80.60.7-0.2-0.20.70.90.40.41.21.21.4-0.41.11.31.31.30.11.3-0.6
Delta ambulatory time before/after self-admin0.60.81.80.80.70.7-0.3-0.30.80.80.40.41.21.21.3-0.60.91.21.21.30.21.2-0.3
Parametrial fat weight1.43.47.3-2.2-1.5-1.61.21.2-1.7-1.8-1.8-1.3-2.6-2.6-2.00.8-2.7-2.1-2.2-2.5-0.1-1.40.7
Pavlov. Cond. lever latency0.20.30.8-0.4-0.1-0.30.00.00.2-0.5-0.0-0.1-0.7-0.8-0.70.0-0.6-0.9-0.9-0.90.5-0.80.4
Pavlov. Cond. magazine entry latency1.01.32.11.41.31.4-1.0-1.00.91.41.41.41.31.31.0-1.01.41.01.11.10.60.20.2
Pavlov. Cond. change in total contacts1.11.21.9-1.4-1.3-1.31.01.0-1.2-1.2-1.4-1.2-1.3-1.2-0.71.3-1.3-0.8-0.9-0.9-1.2-0.1-0.5
Pavlov. Cond. index score0.81.11.81.30.91.2-0.7-0.70.61.30.91.01.31.31.2-0.61.31.31.31.30.10.7-0.2
Pavlov. Cond. latency score0.81.01.71.20.81.1-0.7-0.70.51.20.80.91.31.31.2-0.51.31.31.31.30.10.8-0.2
Pavlov. Cond. lever contacts0.40.41.10.60.30.6-0.2-0.20.10.80.20.40.90.90.9-0.10.81.11.01.0-0.40.8-0.4
Pavlov. Cond. magazine entry number0.81.02.0-1.2-1.3-1.41.11.1-0.9-1.3-1.3-1.4-0.9-0.9-0.71.0-1.1-0.6-0.6-0.6-0.80.1-0.5
Pavlov. Cond. intertrial magazine entries1.41.74.1-0.2-1.3-0.71.81.8-2.0-0.3-1.3-1.20.70.80.81.30.51.41.41.6-1.71.2-1.9
Pavlov. Cond. lever-magazine prob. diff.1.11.32.21.41.01.3-0.8-0.80.61.41.01.11.51.51.3-0.61.51.41.41.40.10.8-0.2
Pavlov. Cond. response bias0.30.40.80.60.40.7-0.3-0.30.10.80.40.50.70.80.9-0.10.90.80.80.8-0.30.6-0.4
Pavlov. Cond. lever latency2.23.07.0-1.8-2.4-2.21.81.8-1.8-1.8-2.5-2.4-1.0-0.9-0.22.6-1.2-0.2-0.3-0.2-2.41.3-1.7
Pavlov. Cond. magazine entry latency0.00.00.20.40.00.20.10.1-0.30.10.40.20.20.2-0.0-0.20.30.00.10.20.2-0.1-0.1
Pavlov. Cond. change in total contacts0.10.20.60.60.60.7-0.3-0.30.20.60.70.70.30.30.4-0.70.40.20.20.20.6-0.10.3
Pavlov. Cond. index score0.60.92.01.21.21.2-0.8-0.80.71.11.41.30.70.70.3-1.40.80.20.30.41.3-0.50.7
Pavlov. Cond. latency score0.71.02.11.31.21.3-0.7-0.70.61.21.41.30.90.90.6-1.41.00.50.60.61.2-0.30.6
Pavlov. Cond. lever contacts2.33.26.82.02.42.3-2.0-2.01.92.02.62.51.21.10.5-2.61.40.40.50.42.2-1.11.6
Pavlov. Cond. magazine entry number0.50.61.8-0.2-0.6-0.50.60.6-0.4-0.1-0.8-0.70.40.50.71.00.30.80.80.8-1.31.1-1.2
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.5-0.3-0.4-0.1-0.10.1-0.3-0.4-0.3-0.2-0.2-0.20.4-0.2-0.1-0.1-0.1-0.40.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.81.12.51.31.31.3-0.9-0.90.81.11.51.40.80.80.4-1.60.90.30.40.41.4-0.50.8
Pavlov. Cond. response bias1.41.84.41.41.81.7-1.5-1.51.31.32.01.90.60.5-0.1-2.10.8-0.1-0.0-0.02.0-1.31.5
Time in closed arm before self-admin0.10.20.7-0.6-0.5-0.40.60.6-0.8-0.3-0.5-0.4-0.3-0.3-0.10.0-0.7-0.1-0.1-0.1-0.30.10.3
Time in closed arm after self-admin2.02.23.71.51.31.6-0.9-0.91.11.81.21.41.91.91.9-1.31.61.91.91.80.51.30.1
Time in open arm before self-admin0.80.91.71.11.10.9-0.2-0.20.70.90.80.61.31.31.1-0.61.31.11.11.30.40.6-0.5
Time in open arm after self-admin0.50.61.4-0.6-0.6-0.60.30.3-0.7-0.7-0.5-0.3-1.2-1.1-1.00.9-0.7-1.0-1.1-1.2-0.2-0.9-0.3
Bone: periosteal estimation0.40.92.3-0.7-1.3-1.01.21.2-1.5-0.9-1.1-1.1-0.5-0.5-0.11.3-0.4-0.2-0.2-0.1-1.30.5-1.1
Bone: periosteal perimeter1.32.25.2-1.3-2.1-1.61.81.8-2.1-1.4-1.8-1.8-0.5-0.50.12.3-0.40.0-0.00.1-2.21.3-2.0
Bone: post-yield work0.10.10.7-0.1-0.4-0.30.60.6-0.8-0.2-0.1-0.30.10.10.20.30.20.10.10.2-0.50.3-0.6
Progressive ratio test 1 active lever presses0.30.41.5-0.4-0.7-0.30.90.9-0.8-0.2-0.9-0.5-0.1-0.00.50.6-0.20.50.30.3-0.90.6-1.2
Progressive ratio test 1 breakpoint0.40.41.8-0.5-0.8-0.30.90.9-0.9-0.2-0.9-0.6-0.1-0.00.50.7-0.20.50.40.3-0.90.6-1.3
Progressive ratio test 1 inactive lever presses2.53.67.2-2.3-2.3-1.72.42.4-2.6-1.4-2.7-1.9-1.4-1.20.52.5-1.3-0.1-0.3-0.5-2.51.5-2.6
Progressive ratio test 2 active lever presses0.50.61.6-0.6-0.8-0.81.31.3-1.0-0.9-0.7-0.9-0.6-0.6-0.80.7-0.4-0.5-0.5-0.3-0.3-0.3-1.0
Progressive ratio test 2 breakpoint0.40.51.3-0.6-0.7-0.81.11.1-0.9-0.9-0.6-0.8-0.6-0.5-0.90.6-0.4-0.5-0.5-0.3-0.2-0.4-0.8
Progressive ratio test 2 inactive lever presses0.81.23.0-1.3-1.3-1.01.71.7-1.5-0.8-1.5-1.1-0.7-0.70.21.3-0.6-0.1-0.2-0.3-1.30.9-1.7
Incentive Sensitization - Responses0.40.61.3-0.7-0.6-1.01.11.1-0.9-1.1-0.5-1.0-0.5-0.6-1.10.5-0.5-0.8-0.7-0.4-0.2-0.6-0.1
Incentive Sensitization - Breakpoint0.40.61.6-0.6-0.5-1.01.01.0-0.8-1.1-0.3-0.9-0.5-0.6-1.30.4-0.4-0.8-0.7-0.50.0-0.8-0.0
Sum of active levers in priming session hrs 5-60.40.41.1-0.6-0.8-0.90.60.6-0.7-0.8-0.9-1.1-0.2-0.30.20.8-0.5-0.0-0.1-0.0-0.80.8-0.7
Progressive ratio0.30.41.40.60.20.7-0.6-0.60.40.80.10.40.70.81.2-0.20.41.00.90.7-0.30.8-0.2
Food seeking constrained by brief footshock2.42.96.7-1.3-2.1-1.62.32.3-2.1-1.2-2.2-2.0-0.3-0.20.92.3-0.50.70.50.5-2.62.0-2.4
Seeking ratio, punishment vs. effort1.21.74.3-1.4-1.5-1.42.12.1-1.9-1.2-1.5-1.5-0.7-0.6-0.21.8-0.4-0.2-0.10.1-1.50.8-1.6
Retroperitoneal fat weight0.52.13.2-1.8-1.6-1.61.61.6-1.8-1.6-1.6-1.4-1.7-1.7-1.41.2-1.5-1.4-1.4-1.5-0.8-0.6-0.4
Reaction time number correct0.10.20.7-0.30.1-0.1-0.3-0.30.3-0.30.10.1-0.6-0.7-0.30.1-0.4-0.8-0.8-0.80.4-0.20.2
Reaction time mean minus median0.92.26.01.41.91.5-2.0-2.02.41.12.01.70.60.5-0.1-2.10.6-0.3-0.2-0.22.1-0.71.9
Reaction time mean minus median AUC0.61.53.51.41.71.2-1.5-1.51.90.91.81.40.60.5-0.1-1.80.7-0.2-0.10.01.8-0.61.4
Reaction time num false alarms0.81.12.4-1.3-1.4-1.41.61.6-1.1-1.2-1.2-1.4-0.5-0.5-0.61.3-0.5-0.3-0.2-0.1-1.00.4-0.9
Reaction time num false alarms AUC0.71.22.7-1.1-1.4-1.41.61.6-1.2-1.2-1.3-1.6-0.1-0.1-0.41.4-0.30.10.10.4-1.20.7-1.2
Reaction time trials correct on left0.10.20.7-0.30.1-0.1-0.3-0.30.3-0.30.10.1-0.6-0.7-0.30.1-0.4-0.8-0.8-0.80.4-0.20.2
Reaction time trials on left0.10.20.7-0.30.1-0.1-0.4-0.40.4-0.30.20.1-0.6-0.6-0.30.0-0.4-0.8-0.8-0.80.4-0.20.3
Reaction time mean0.60.92.61.31.21.0-1.2-1.21.60.91.00.90.90.80.5-1.30.60.60.60.50.7-0.20.7
Reaction time mean AUC0.81.33.01.61.41.2-1.3-1.31.71.21.21.11.21.20.9-1.41.00.90.90.80.80.20.6
Median of all reaction times0.40.61.51.20.90.9-0.9-0.91.20.90.60.60.90.80.7-0.90.60.90.80.70.20.10.3
Reaction time omissions0.71.02.61.21.30.9-1.2-1.21.60.81.20.90.80.70.1-1.60.70.30.30.41.2-0.70.9
Reaction time false alarm rate0.91.23.0-0.9-1.4-1.31.71.7-1.3-1.0-1.3-1.60.20.2-0.31.3-0.10.50.50.7-1.30.8-1.3
Reaction time premature initiation rate2.12.84.92.01.82.1-1.5-1.51.32.21.61.82.02.11.8-1.32.01.91.91.80.70.50.1
Reaction time premature initiations0.81.52.61.41.51.6-1.4-1.41.31.61.41.51.21.21.2-1.11.31.01.00.90.80.00.3
Std. dev. reaction times0.81.54.31.31.61.2-1.6-1.62.10.91.61.20.80.70.0-1.80.70.00.10.11.6-0.51.4
Reaction time trials completed0.10.20.7-0.30.1-0.1-0.4-0.40.4-0.30.20.1-0.6-0.6-0.30.0-0.4-0.8-0.8-0.80.4-0.20.3
Reaction time trials AUC0.10.20.6-0.3-0.0-0.2-0.2-0.20.3-0.30.00.0-0.6-0.7-0.20.2-0.4-0.8-0.8-0.80.2-0.00.1
Run reversals in cocaine runway, females0.70.72.00.9-0.00.30.70.7-0.20.30.3-0.11.11.20.70.11.21.11.11.4-0.11.0-1.3
Run reversals in cocaine runway, males0.10.10.3-0.4-0.2-0.20.30.30.0-0.2-0.3-0.1-0.6-0.5-0.10.2-0.5-0.4-0.4-0.5-0.10.20.1
Latency to leave start box in cocaine runway0.40.41.1-0.5-0.8-1.00.80.8-0.8-0.8-0.8-1.1-0.2-0.3-0.30.8-0.5-0.1-0.10.0-0.9-0.1-0.2
Latency to leave start box in cocaine runway, F1.31.43.5-1.0-1.6-1.71.71.7-1.5-1.6-1.4-1.9-0.5-0.5-0.91.2-0.8-0.4-0.3-0.0-1.2-0.0-0.9
Latency to leave start box in cocaine runway, M0.30.30.90.51.00.6-0.9-0.90.60.70.30.70.30.30.8-0.20.30.40.30.10.0-0.10.7
Std. dev. time between licks in bursts0.10.10.5-0.3-0.4-0.20.60.6-0.7-0.20.0-0.1-0.2-0.20.10.50.1-0.3-0.2-0.1-0.20.7-0.5
Total sessions with >9 infusions1.01.32.41.21.31.5-1.0-1.00.91.61.11.41.21.21.4-1.21.11.21.11.00.60.40.2
Short access day 1 total inactive lever presses1.52.04.7-1.5-1.7-1.41.41.4-1.6-1.3-1.9-1.4-1.6-1.5-0.42.2-1.3-0.8-1.0-1.1-1.60.3-1.4
Short access day 10 total inactive lever presses0.10.21.0-0.3-0.30.20.20.2-0.30.3-0.50.2-0.3-0.20.50.70.10.30.2-0.1-0.60.2-1.0
Short access day 1 total infusions1.01.43.81.11.11.5-1.1-1.11.01.60.81.31.11.22.0-0.71.31.41.31.00.11.2-0.4
Short access day 10 total infusions0.40.61.10.50.70.8-0.1-0.10.20.90.50.61.01.01.0-0.61.01.01.01.10.10.5-0.6
Short access total infusions0.10.10.50.20.40.5-0.2-0.20.10.50.10.40.30.30.7-0.20.20.50.40.3-0.10.3-0.2
Short access day 1 locomotion1.82.37.41.21.11.4-1.0-1.00.81.70.61.11.71.82.7-0.51.72.12.01.8-0.42.1-0.8
Short access day 10 total locomotion1.93.511.41.61.12.1-1.3-1.31.22.40.81.62.02.13.4-0.81.82.62.42.1-0.32.4-1.0
Short access total locomotion2.02.55.71.51.42.0-1.5-1.51.32.21.11.81.61.72.4-1.21.51.91.81.50.31.30.1
One hour access (0.3 mA shock)0.50.61.3-0.9-0.9-0.61.11.1-0.9-0.6-1.0-0.8-0.5-0.50.11.0-0.6-0.0-0.1-0.2-0.80.6-1.1
Compulsive drug intake0.91.12.21.11.21.0-1.1-1.11.31.01.40.91.41.30.6-1.01.50.80.91.10.90.10.2
One hour access (shock baseline)0.30.51.1-0.7-0.9-0.61.01.0-0.9-0.6-1.0-0.7-0.8-0.7-0.10.7-0.9-0.3-0.5-0.6-0.70.3-0.7
Social response proportion0.50.61.5-1.0-0.9-0.80.70.7-0.8-0.7-1.2-0.8-0.9-0.8-0.10.6-1.0-0.4-0.5-0.6-0.50.4-0.2
Social responses1.62.14.5-1.9-1.5-1.51.11.1-1.1-1.5-1.6-1.2-1.9-1.9-1.41.0-2.1-1.5-1.6-1.7-0.4-0.00.6
Social time0.20.30.9-0.6-0.3-0.4-0.2-0.20.2-0.5-0.5-0.3-0.8-0.9-0.5-0.1-0.8-0.7-0.8-1.00.20.30.7
Soleus weight0.82.35.6-1.3-2.0-1.62.12.1-1.7-1.2-1.9-1.8-0.3-0.20.32.1-0.30.40.30.4-2.41.8-2.1
Bone: stiffness0.00.10.30.20.20.40.00.0-0.30.50.40.50.20.20.1-0.20.30.20.20.20.2-0.20.1
Tibialis anterior weight0.93.25.1-2.2-1.9-2.22.12.1-2.0-2.2-1.8-2.0-1.9-1.9-1.61.3-2.0-1.7-1.7-1.6-1.0-0.7-0.4
Time to tail flick, vehicle, before self-admin0.80.83.90.0-0.20.20.20.2-0.10.4-0.6-0.20.60.71.90.50.41.21.10.9-1.22.0-1.2
Time to tail flick, vehicle, after self-admin0.20.21.00.5-0.40.00.20.20.20.1-0.2-0.20.50.50.60.20.20.70.60.6-0.41.0-0.5
Time to tail flick, test, before self-admin0.50.51.40.30.70.4-0.9-0.90.90.20.70.6-0.2-0.2-0.8-0.8-0.1-0.6-0.5-0.51.0-1.21.2
Time to tail flick, test, after self-admin2.02.14.4-1.6-1.8-1.51.61.6-1.9-1.2-2.1-1.7-1.0-0.90.22.0-0.8-0.1-0.2-0.1-2.11.0-2.1
Delta time to tail flick, vehicle, before/after SA0.10.10.40.70.00.20.00.00.20.20.40.10.60.6-0.0-0.40.50.40.50.60.30.2-0.0
Delta time to tail flick, test, before/after SA1.41.43.0-1.2-1.5-1.11.41.4-1.6-0.9-1.7-1.2-0.8-0.70.31.7-0.70.0-0.1-0.2-1.71.0-1.6
Tibia length0.51.33.00.9-0.60.01.01.0-1.10.3-0.2-0.41.31.31.21.01.31.51.51.7-1.31.5-1.7
Ambulatory time before self-admin0.30.51.3-0.5-0.9-0.70.70.7-0.8-0.8-0.6-0.7-0.7-0.6-0.81.0-0.2-0.6-0.6-0.5-0.5-0.4-1.2
Ambulatory time after self-admin0.30.32.30.2-0.10.10.10.1-0.10.2-0.2-0.20.40.50.80.50.70.70.60.7-0.50.9-1.5
Bone: tissue strength0.90.92.5-0.20.70.3-0.9-0.90.7-0.00.70.6-0.8-0.8-1.1-0.8-0.7-1.2-1.2-1.21.2-1.61.5
Total heroin consumption0.10.10.50.10.30.2-0.7-0.70.40.10.00.10.0-0.00.5-0.3-0.30.0-0.1-0.20.20.30.5
Bone: trabecular number0.00.00.10.20.20.10.10.1-0.00.10.10.10.10.10.3-0.30.10.10.10.10.00.0-0.0
Bone: trabecular spacing0.60.91.5-1.2-1.2-1.11.21.2-1.2-1.1-1.0-1.1-0.8-0.8-0.61.0-0.8-0.6-0.6-0.5-0.70.1-0.7
Bone: trabecular thickness0.81.02.41.30.50.8-0.0-0.00.01.00.60.51.41.51.1-0.41.31.51.51.5-0.10.9-0.6
Bone: trabecular tissue density0.50.71.90.71.00.8-1.3-1.31.10.61.00.90.20.2-0.2-1.30.3-0.2-0.1-0.11.4-0.71.1
Water consumed over 24 hours1.11.53.6-1.3-0.3-0.80.20.2-0.2-1.0-0.4-0.4-1.7-1.7-1.7-0.2-1.5-1.8-1.8-1.80.7-1.91.0
Number of responses in last shaping day0.40.51.60.10.10.40.00.0-0.20.6-0.00.30.60.61.30.30.90.90.80.8-0.51.2-1.2