Hub : Genes

Ogdh

oxoglutarate dehydrogenase

chr14:85363949–85431405 (+)

Ogdh RatGTEx page

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_039092218.2 0.02 0.01 4.2e-05 0.03 0.03 0.03 0.03 5.3e-05 3.6e-05 2.9e-05 6.2e-05
2 Brain mRNA stability Ogdh 0.11 0.06 6.5e-10 0.12 0.11 0.11 0.11 6.3e-11 2.1e-10 1.7e-10 2.5e-10
3 NAcc intron excision ratio chr14_85394599_85403711 0.01 0.01 2.8e-03 0.01 0.01 0.01 0.01 4.5e-03 7.2e-03 3.9e-02 9.9e-03
4 Brain intron excision ratio chr14_85387865_85394555 0.02 0.02 8.7e-03 0.01 0.02 0.01 0.01 2.2e-02 6.4e-03 1.5e-02 1.2e-02
5 Liver mRNA stability Ogdh 0.13 0.08 1.3e-13 0.06 0.11 0.11 0.11 1.6e-07 1.2e-12 4.3e-12 8.2e-12
6 RMTg mRNA stability Ogdh 0.17 0.1 2.4e-04 0.11 0.13 0.1 0.12 9.1e-04 2.3e-04 1.3e-03 5.8e-04
7 NAcc intron excision ratio chr14_85387865_85403711 0.02 0.01 2.1e-04 0.03 0.02 0.02 0.02 6.1e-05 4.6e-04 1.1e-03 2.3e-04
8 NAcc isoform ratio XM_006251446.5 0.01 0.01 1.0e-02 0 -0 0 0 8.5e-02 4.2e-01 3.4e-01 3.5e-01
9 IC gene expression Ogdh 0.05 0.04 3.5e-03 0.02 0.05 0.04 0.03 3.3e-02 3.5e-03 1.2e-02 2.8e-02
10 Eye intron excision ratio chr14_85384144_85387550 0.25 0.15 8.2e-03 0.2 0.13 0.11 0.14 5.4e-04 4.6e-03 8.2e-03 4.0e-03
11 pVTA gene expression Ogdh 0.06 0.04 2.5e-04 0.04 0.05 0.04 0.04 2.9e-04 3.8e-05 2.3e-04 2.1e-04
12 NAcc gene expression Ogdh 0.07 0.04 1.1e-09 0.06 0.06 0.06 0.06 3.1e-09 3.7e-10 1.2e-09 1.5e-09
13 PL gene expression Ogdh 0.08 0.05 2.7e-06 0.05 0.05 0.06 0.06 4.5e-06 2.9e-06 8.1e-07 1.1e-06
14 IL gene expression Ogdh 0.33 0.19 5.2e-03 0.03 0.09 0.1 0.06 5.9e-02 3.7e-03 2.6e-03 1.7e-02
15 OFC gene expression Ogdh 0.29 0.15 2.3e-03 0 0.05 0.05 0.03 2.6e-01 2.2e-02 2.8e-02 6.5e-02
16 Liver gene expression Ogdh 0.13 0.07 4.0e-10 0.05 0.06 0.06 0.06 1.3e-06 1.6e-07 3.2e-07 3.4e-07
17 Brain gene expression Ogdh 0.24 0.1 1.1e-14 0.04 0.14 0.13 0.13 1.1e-04 3.5e-13 1.7e-12 2.4e-12
18 PL intron excision ratio chr14_85394599_85403711 0.03 0.03 8.9e-03 0.01 0.01 0.02 0.01 1.4e-02 9.4e-03 4.1e-03 9.0e-03
19 Brain intron excision ratio chr14_85394599_85403711 0.04 0.03 4.1e-03 0.01 0.02 0.02 0.02 2.3e-02 2.9e-03 2.4e-03 4.2e-03
20 Adipose gene expression Ogdh 0.04 0.03 8.1e-03 0.04 0.01 0.03 0.03 8.0e-05 4.1e-02 2.5e-04 3.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.10.20.20.4-0.10.20.30.30.10.10.2-0.30.30.30.30.40.30.30.30.0-0.20.1
Area under the delay curve2.83.37.7-2.4-1.8-2.6-2.2-2.1-1.92.82.8-2.51.8-0.7-0.6-1.0-0.2-0.0-0.00.3-2.1-2.01.2
BMI with tail0.10.51.1-0.8-1.1-0.8-0.8-0.9-0.90.80.8-0.80.2-0.7-0.7-0.8-0.8-0.6-0.6-0.7-0.30.3-0.1
BMI without tail0.31.02.2-1.3-1.5-1.3-1.3-1.1-0.91.31.3-1.11.0-0.9-0.8-0.9-0.5-0.5-0.4-0.5-0.9-0.30.1
Body weight1.35.711.0-3.2-2.8-3.2-2.9-3.0-2.73.33.3-3.02.7-1.9-1.8-2.0-1.2-1.2-1.1-1.0-2.3-1.60.4
Weight adjusted by age0.10.20.5-0.5-0.2-0.5-0.6-0.6-0.50.60.6-0.70.6-0.1-0.1-0.3-0.00.00.00.1-0.6-0.50.3
Bone surface0.10.10.2-0.3-0.1-0.4-0.2-0.3-0.40.50.5-0.30.3-0.5-0.5-0.3-0.3-0.5-0.5-0.4-0.2-0.3-0.3
Bone volume0.10.20.5-0.3-0.3-0.6-0.3-0.4-0.50.70.7-0.40.2-0.5-0.4-0.4-0.3-0.4-0.4-0.4-0.2-0.3-0.3
Breakpoint value in progressive ratio session0.20.20.6-0.4-0.4-0.3-0.6-0.7-0.70.30.3-0.80.4-0.4-0.5-0.7-0.3-0.4-0.4-0.4-0.3-0.10.0
Number of licking bursts1.72.74.9-2.1-1.6-2.0-1.8-2.1-2.12.22.2-2.21.9-1.3-1.2-1.4-1.5-1.0-1.0-0.6-1.5-1.1-0.6
Context. condit. distance diff. score1.72.14.21.81.91.82.01.71.5-1.7-1.71.8-1.71.31.21.40.40.70.60.71.71.0-0.4
Locomotion velocity, session 10.30.41.00.80.30.80.60.70.6-1.0-1.00.8-0.8-0.00.00.20.3-0.1-0.1-0.20.60.6-0.4
Locomotion distance, session 11.41.74.50.21.20.00.10.61.0-0.2-0.20.10.21.71.71.72.12.02.02.0-1.0-1.42.0
Locomotion velocity, session 20.70.81.50.9-0.01.20.70.50.2-1.2-1.20.9-0.9-0.8-0.8-0.5-0.3-1.1-1.1-1.20.91.1-1.1
Locomotion distance, session 20.81.22.01.11.21.00.81.31.4-1.2-1.21.2-0.71.11.21.21.41.11.21.00.30.00.7
Locomotion velocity, session 31.31.53.11.11.41.21.31.31.4-1.2-1.21.2-0.41.41.41.81.51.21.21.2-0.2-0.30.9
Locomotion distance, session 30.40.41.2-0.9-1.0-0.4-0.7-0.8-0.80.30.3-0.71.1-0.7-0.7-0.6-0.5-0.6-0.6-0.6-0.9-0.2-0.0
Stereotopy head waving bouts, day 30.50.61.30.80.90.80.61.01.1-0.8-0.80.9-0.50.70.70.81.10.70.80.6-0.0-0.10.6
Stereotopy head waving duration, day 31.92.33.82.01.81.81.61.91.9-1.8-1.81.9-1.71.31.31.41.41.01.00.91.10.70.2
Locomotion velocity, session 70.20.20.4-0.3-0.6-0.2-0.4-0.5-0.50.30.3-0.40.1-0.6-0.5-0.5-0.5-0.5-0.5-0.50.00.1-0.5
Locomotion distance, session 70.10.20.80.30.10.40.40.10.0-0.2-0.20.2-0.50.10.1-0.1-0.6-0.1-0.2-0.00.90.7-0.7
Stereotopy head waving bouts, day 70.10.10.40.20.40.20.50.30.3-0.4-0.40.3-0.10.20.20.60.60.10.10.2-0.5-0.50.3
Stereotopy head waving duration, day 70.20.31.20.10.4-0.10.20.30.4-0.2-0.20.20.20.40.40.71.10.50.50.5-0.9-0.90.8
Locomotion velocity, session 80.91.02.31.31.31.41.51.21.0-1.5-1.51.4-1.00.50.40.80.30.0-0.10.10.90.7-0.6
Locomotion distance, session 84.36.29.83.03.12.93.03.13.0-3.0-3.03.1-2.62.32.32.51.71.71.61.52.21.30.2
Degree of sensitization distance2.12.25.42.01.81.61.91.71.5-1.4-1.41.7-2.21.21.11.00.20.60.50.72.31.5-1.0
Degree of sensitization stereotypy0.10.10.5-0.20.0-0.30.0-0.1-0.10.10.1-0.10.4-0.0-0.00.20.4-0.0-0.00.1-0.7-0.60.3
Conditioned locomotion1.11.33.70.11.1-0.20.10.60.90.10.10.20.31.61.71.41.51.91.91.9-0.8-1.11.4
Cocaine response after cond. corrected1.01.32.1-1.4-1.2-1.4-1.2-1.4-1.41.31.3-1.51.2-0.8-0.8-0.5-0.5-0.6-0.7-0.4-1.5-1.40.2
Cocaine response after cond. not corrected1.41.63.0-1.6-1.4-1.6-1.4-1.7-1.61.61.6-1.71.4-0.8-0.7-0.5-0.4-0.5-0.5-0.2-1.7-1.60.4
Cocaine response before conditioning0.20.20.60.30.50.10.30.40.5-0.0-0.00.2-0.20.80.80.60.50.70.70.70.0-0.00.4
Saline control response0.20.20.60.60.30.70.60.50.5-0.8-0.80.7-0.40.10.10.40.3-0.1-0.1-0.10.10.3-0.3
Bone: connectivity density0.10.20.60.60.70.40.50.50.5-0.3-0.30.5-0.70.40.30.40.30.20.20.20.50.2-0.0
Bone: cortical apparent density0.30.40.8-0.7-0.9-0.3-0.7-0.7-0.80.40.4-0.70.7-0.8-0.8-0.7-0.4-0.7-0.6-0.7-0.6-0.3-0.0
Bone: cortical area1.52.44.5-2.0-1.6-2.1-1.9-1.8-1.62.02.0-1.92.0-1.0-1.0-0.9-0.3-0.5-0.5-0.5-2.0-1.70.8
Bone: cortical porosity0.10.10.60.3-0.0-0.00.00.10.0-0.2-0.20.1-0.8-0.1-0.1-0.3-0.2-0.1-0.1-0.10.60.5-0.4
Bone: cortical porosity0.10.20.60.40.5-0.10.30.30.4-0.1-0.10.2-0.80.50.50.40.30.50.50.50.50.20.0
Bone: cortical thickness1.11.93.7-1.8-1.4-1.8-1.7-1.6-1.41.91.9-1.71.7-0.7-0.7-0.7-0.1-0.2-0.2-0.2-1.7-1.61.0
Bone: cortical thickness1.01.23.30.11.0-0.80.40.40.61.21.20.1-0.21.51.51.61.21.61.51.8-0.4-1.31.1
Bone: cortical tissue density0.30.50.9-0.7-1.0-0.3-0.7-0.8-0.80.40.4-0.70.7-0.9-0.9-0.8-0.5-0.8-0.8-0.8-0.5-0.2-0.1
Condit. Reinf. active minus inactive responses1.31.52.8-0.9-1.7-0.9-1.0-1.2-1.30.80.8-0.90.6-1.7-1.7-1.6-1.4-1.6-1.5-1.6-0.40.3-1.3
Condit. Reinf. active-inactive response ratio1.51.64.80.6-0.60.70.6-0.0-0.5-0.8-0.80.4-1.1-1.3-1.4-1.2-1.6-1.8-1.8-1.81.31.9-2.2
Condit. Reinf. active responses0.60.81.6-0.9-1.3-1.0-0.9-0.9-0.90.80.8-0.80.8-1.1-1.0-1.0-0.8-0.9-0.9-0.8-0.7-0.1-0.8
Condit. Reinf. inactive responses0.70.82.1-1.1-0.6-1.2-1.0-0.8-0.61.21.2-1.01.40.10.1-0.00.30.50.50.6-1.4-1.40.7
Incentive salience index mean1.62.03.2-1.6-1.8-1.8-1.6-1.6-1.61.61.6-1.51.5-1.5-1.5-1.5-1.0-1.1-1.1-1.1-1.3-0.7-0.5
Condit. Reinf. lever presses1.21.75.0-1.6-0.9-1.9-1.5-1.1-0.81.61.6-1.42.0-0.10.0-0.00.50.50.60.6-2.2-2.01.2
Condit. Reinf. active minus inactive responses0.20.20.50.40.50.10.60.60.6-0.4-0.40.5-0.40.60.60.70.50.50.50.60.30.00.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.5-0.3-0.5-0.3-0.3-0.20.20.2-0.40.40.10.10.10.20.30.20.3-0.5-0.50.4
Condit. Reinf. active responses0.30.50.90.70.70.50.80.91.0-0.7-0.70.9-0.60.70.70.80.70.60.60.50.50.30.2
Condit. Reinf. inactive responses0.70.92.01.41.11.11.31.31.2-1.0-1.01.4-1.30.70.60.70.50.30.30.21.20.9-0.3
Condit. Reinf. lever presses0.20.20.60.30.7-0.20.60.50.50.10.10.4-0.30.70.70.80.50.60.50.70.1-0.30.3
Condit. Reinf. lever reinforcers received0.20.30.60.50.60.20.60.70.7-0.3-0.30.7-0.50.60.60.70.60.60.60.50.40.00.3
Conditioned reinforcement - actives0.00.10.2-0.1-0.4-0.4-0.3-0.00.00.40.40.00.4-0.3-0.3-0.20.2-0.1-0.1-0.3-0.2-0.40.2
Conditioned reinforcement - inactives0.30.41.2-0.6-0.9-1.0-0.7-0.5-0.51.01.0-0.50.8-0.6-0.5-0.4-0.2-0.4-0.3-0.4-0.5-1.10.0
Conditioned locomotion0.60.81.9-0.9-1.1-1.0-1.3-0.8-0.61.21.2-0.61.4-1.0-0.9-0.80.2-0.4-0.3-0.7-1.2-0.60.5
Patch foraging indifference point 0 sec2.34.39.9-1.7-2.5-1.1-1.3-2.3-2.71.41.4-1.91.0-2.4-2.5-2.5-3.1-2.6-2.7-2.30.00.9-2.1
Patch foraging indifference point AUC0.20.31.7-0.0-0.4-0.1-0.1-0.1-0.20.10.10.1-0.0-0.6-0.6-0.5-0.9-0.6-0.6-0.60.40.5-1.3
Delay disc. indifference point, 0s delay1.31.44.5-1.4-1.0-1.3-1.0-1.6-1.62.12.1-1.91.1-0.1-0.2-0.3-0.9-0.1-0.20.3-0.9-1.30.5
Delay disc. indifference point, 16s delay1.21.32.4-1.6-1.3-1.5-1.5-1.3-1.21.51.5-1.40.9-1.0-1.0-1.2-0.4-0.6-0.5-0.6-1.2-0.80.3
Delay disc. indifference point, 2s delay2.52.87.0-1.8-1.3-2.5-1.8-1.9-1.62.62.6-2.41.80.00.0-0.30.10.50.50.9-2.0-2.31.5
Delay disc. indifference point, 24s delay1.01.23.1-1.7-1.2-1.5-1.4-1.4-1.31.41.4-1.50.7-0.8-0.7-1.1-0.7-0.4-0.4-0.3-0.9-0.70.2
Delay disc. indifference point, 4s delay3.43.68.2-2.1-1.7-2.7-2.3-2.2-1.92.92.9-2.52.3-0.5-0.4-0.70.20.20.20.5-2.5-2.51.5
Delay disc. indifference point, 8s delay1.21.43.3-1.7-0.8-1.7-1.4-1.0-0.71.51.5-1.31.3-0.00.1-0.10.50.60.60.7-1.6-1.81.4
Indifference point function ln k0.10.20.6-0.30.0-0.5-0.4-0.10.10.50.5-0.30.20.50.50.30.80.70.80.7-0.6-0.60.7
Indifference point function log k0.10.20.6-0.30.0-0.5-0.4-0.10.10.50.5-0.30.20.50.50.30.80.70.80.7-0.6-0.60.7
Patch foraging total patch changes 0 sec2.54.811.1-1.7-2.6-1.2-1.3-2.4-2.71.51.5-1.90.9-2.6-2.6-2.7-3.3-2.8-2.9-2.50.11.0-2.4
Patch foraging total patch changes 12 sec2.12.88.5-0.9-1.7-0.5-0.7-1.5-1.90.80.8-1.10.2-2.0-2.0-2.0-2.9-2.2-2.3-2.10.71.3-2.2
Patch foraging total patch changes 18 sec2.43.79.1-1.4-2.2-0.9-0.9-1.9-2.31.21.2-1.40.9-2.4-2.4-2.3-3.0-2.7-2.8-2.40.31.1-1.9
Patch foraging total patch changes 24 sec0.81.44.31.00.11.21.40.50.0-0.8-0.80.9-1.2-0.5-0.6-0.3-1.7-1.2-1.4-1.11.92.1-1.8
Patch foraging total patch changes 6 sec2.74.18.6-1.5-2.4-1.0-1.3-2.1-2.41.31.3-1.70.9-2.6-2.6-2.6-2.9-2.6-2.7-2.50.00.9-2.2
Patch foraging time to switch 0 sec0.30.61.40.60.80.60.60.70.8-0.5-0.50.5-0.31.01.01.01.10.90.90.9-0.1-0.31.2
Patch foraging water rate 0 sec1.43.05.5-1.4-2.1-1.2-1.4-1.7-1.91.01.0-1.31.0-2.3-2.3-2.3-2.1-2.2-2.2-2.2-0.30.6-1.7
Patch foraging water rate 12 sec0.10.20.6-0.5-0.5-0.7-0.3-0.4-0.40.40.4-0.30.6-0.5-0.5-0.5-0.0-0.4-0.4-0.4-0.4-0.10.6
Patch foraging water rate 18 sec0.71.24.6-0.50.3-0.7-0.6-0.10.30.50.5-0.50.91.11.10.91.41.51.61.5-1.2-1.42.1
Patch foraging water rate 24 sec0.10.10.5-0.1-0.4-0.2-0.20.10.1-0.0-0.00.20.4-0.4-0.3-0.20.4-0.2-0.1-0.4-0.4-0.00.7
Patch foraging water rate 6 sec0.40.51.8-0.9-0.4-1.2-1.0-0.4-0.10.70.7-0.51.3-0.1-0.0-0.10.60.40.50.3-1.2-1.10.7
Seeking ratio, delayed vs. immediate footshock0.60.73.10.10.5-0.1-0.30.50.9-0.0-0.00.40.50.70.80.81.81.21.30.9-1.1-1.01.2
Distance traveled before self-admin0.10.10.4-0.3-0.1-0.2-0.1-0.2-0.3-0.0-0.0-0.10.5-0.4-0.40.0-0.6-0.5-0.5-0.4-0.0-0.6-0.6
Distance traveled after self-admin0.20.21.7-0.4-0.0-0.4-0.4-0.2-0.10.30.3-0.40.80.20.20.40.40.40.40.4-0.6-1.30.6
Extensor digitorum longus weight2.18.115.5-3.3-3.9-2.9-3.4-3.4-3.33.13.1-3.12.6-3.2-3.1-3.2-2.2-2.5-2.3-2.5-2.0-1.1-0.5
Bone: elastic displacement0.50.61.51.10.91.20.80.90.8-1.1-1.10.9-1.00.60.50.60.60.30.40.20.60.60.1
Bone: elastic work0.10.10.4-0.30.0-0.3-0.5-0.3-0.20.30.3-0.50.30.10.10.00.40.30.30.3-0.5-0.60.6
Bone: endosteal estimation0.00.10.5-0.40.0-0.7-0.2-0.2-0.20.30.3-0.30.5-0.1-0.1-0.0-0.1-0.1-0.10.0-0.3-0.4-0.0
Bone: endosteal perimeter0.61.33.3-1.6-0.9-1.8-1.2-1.1-0.91.51.5-1.21.8-0.3-0.2-0.20.20.20.20.3-1.6-1.61.0
Epididymis fat weight0.41.22.0-1.4-1.3-1.3-1.3-1.4-1.31.41.4-1.41.3-1.0-1.0-0.9-0.5-0.7-0.7-0.7-1.1-0.70.3
Delta time in closed arm before/after self-admin8.98.312.72.93.32.82.63.33.5-2.7-2.72.8-2.23.43.43.53.63.13.12.90.9-0.32.2
Delta time in open arm before/after self-admin6.06.09.6-2.7-2.5-2.3-2.2-2.7-2.92.02.0-2.32.2-3.0-3.0-2.7-3.1-2.8-2.8-2.7-0.9-0.4-1.8
Diff in mean of infusions in LGA sessions0.20.31.10.20.30.4-0.10.00.2-0.1-0.1-0.2-0.00.60.60.31.00.70.70.7-0.5-0.31.1
Delay discount exponential model param2.93.27.62.41.82.72.22.11.9-2.8-2.82.5-1.70.60.61.00.30.00.0-0.32.12.0-1.2
Extinction: sum of active levers before priming0.10.10.4-0.2-0.4-0.1-0.3-0.1-0.1-0.1-0.10.00.3-0.5-0.5-0.6-0.0-0.4-0.3-0.6-0.10.2-0.1
Active lever presses in extinction session 60.70.72.40.30.50.30.10.30.5-0.3-0.3-0.0-0.21.11.10.91.51.11.21.1-0.5-0.71.5
Bone: final force0.20.40.9-0.4-0.7-0.5-0.5-0.5-0.60.30.3-0.30.2-1.0-0.9-0.8-0.7-0.9-0.8-0.9-0.00.2-0.5
Bone: final moment0.30.51.1-0.5-0.9-0.6-0.7-0.7-0.80.40.4-0.50.4-1.1-1.0-1.0-0.8-0.9-0.9-1.0-0.10.2-0.5
Food consumed during 24 hour testing period1.31.83.9-0.9-1.8-0.6-1.0-1.2-1.40.60.6-0.80.4-2.0-2.0-1.8-1.4-1.9-1.8-1.9-0.00.6-1.0
Glucose12.920.346.4-2.3-5.5-1.4-2.7-3.5-4.21.01.0-2.10.9-6.6-6.6-6.3-5.6-6.6-6.4-6.81.13.1-4.9
Heart weight1.01.53.7-0.1-0.90.2-0.0-0.6-0.9-0.3-0.3-0.2-0.5-1.5-1.6-1.5-1.6-1.9-1.9-1.90.71.8-1.8
Delay discount hyperbolic model param3.13.58.22.41.82.82.32.21.9-2.9-2.92.5-1.90.60.50.90.1-0.1-0.1-0.42.22.2-1.3
Intermittent access intake day 1-15 change0.81.63.9-0.9-1.1-1.0-0.9-1.1-1.20.90.9-0.70.9-1.8-1.7-1.4-2.0-1.7-1.7-1.7-0.00.3-1.7
Intermittent access intake escalation0.71.53.7-0.9-1.1-1.0-0.9-1.1-1.20.90.9-0.70.9-1.6-1.6-1.3-1.9-1.5-1.5-1.5-0.10.1-1.9
Intermittent access intake escalation 20.80.93.9-0.4-0.5-0.3-0.2-0.5-0.70.30.3-0.20.5-1.2-1.2-0.7-1.9-1.3-1.3-1.20.5-0.0-2.0
Intermitt. access day 1 inactive lever presses0.10.41.20.20.1-0.10.30.60.70.10.10.4-0.00.80.80.91.00.90.90.8-0.0-0.91.1
Intermitt. access day 15 inactive lever presses1.32.74.9-1.6-2.2-1.6-1.5-1.5-1.61.61.6-1.21.4-2.1-2.0-1.9-1.8-1.8-1.8-1.8-0.6-0.1-1.3
Intermitt. access escalation Index0.91.34.3-0.0-0.20.00.0-0.5-0.80.00.0-0.1-0.3-1.3-1.3-1.6-1.9-1.5-1.6-1.50.82.1-1.9
Intermittent access day 1 total infusions0.40.62.4-0.10.1-0.3-0.30.10.20.60.6-0.30.20.70.80.71.11.01.11.1-0.7-1.51.2
Intermittent access day 15 total infusions0.91.42.0-1.1-1.2-1.2-1.3-1.3-1.31.41.4-1.21.1-1.4-1.4-1.3-1.3-1.1-1.1-1.1-0.6-0.7-1.0
Intermittent access terminal intake (last 3 days)0.71.02.5-0.6-0.8-0.6-0.7-0.8-1.00.90.9-0.60.6-1.3-1.2-1.0-1.6-1.2-1.2-1.20.0-0.2-1.6
Intermittent access total infusions0.40.51.0-0.7-0.6-0.7-0.9-0.7-0.81.01.0-0.80.6-0.7-0.7-0.8-0.5-0.5-0.4-0.5-0.5-0.6-0.3
Intermittent access day 1 locomotion1.41.77.50.60.70.50.11.11.4-0.5-0.50.7-0.11.31.41.22.71.71.91.5-0.8-1.42.3
Intermittent access day 15 total locomotion0.30.61.3-0.9-0.8-0.6-1.1-0.7-0.60.80.8-0.81.1-0.6-0.6-0.60.4-0.2-0.1-0.4-1.1-0.80.8
Intermittent access total locomotion0.50.61.4-0.9-0.7-0.7-1.2-0.6-0.50.80.8-0.81.1-0.5-0.4-0.70.6-0.00.2-0.1-1.2-1.01.0
Intermittent access standard deviation0.61.23.01.41.21.31.31.61.5-1.3-1.31.7-1.20.40.40.80.30.20.3-0.11.20.3-1.0
Left kidney weight0.20.83.5-0.9-0.0-0.9-0.9-0.4-0.10.70.7-0.71.10.50.50.31.00.91.00.9-1.2-1.41.9
Right kidney weight0.20.83.5-0.70.1-0.6-0.7-0.4-0.10.70.7-0.80.70.80.80.41.11.01.11.0-1.0-1.11.9
Cocaine induced anxiety1.82.55.2-1.6-1.7-1.3-1.8-1.8-1.91.11.1-1.61.4-2.0-2.0-2.3-1.5-1.7-1.6-1.8-1.00.3-0.7
Post-drug Anxiety2.12.23.9-1.7-1.7-1.3-1.7-1.9-2.01.51.5-1.91.2-1.6-1.6-2.0-1.4-1.4-1.3-1.3-1.00.1-0.3
Baseline Anxiety0.30.30.90.20.30.20.10.10.20.30.3-0.2-0.30.90.80.50.80.80.80.9-0.3-0.31.0
Tail length1.76.712.3-3.4-3.2-2.9-3.4-3.1-2.83.03.0-3.13.5-2.3-2.2-2.3-1.1-1.4-1.3-1.3-2.7-2.10.5
Length with tail1.77.513.3-3.6-3.1-3.4-3.5-3.3-3.13.43.4-3.43.6-2.3-2.2-2.3-1.2-1.4-1.4-1.3-2.7-2.20.4
Length without tail0.41.32.7-1.6-1.1-1.6-1.3-1.6-1.51.61.6-1.61.2-0.8-0.8-0.9-0.8-0.6-0.6-0.5-0.9-0.70.3
LgA early post infusion interval0.10.20.8-0.5-0.4-0.6-0.7-0.4-0.20.40.4-0.40.5-0.1-0.1-0.30.40.20.30.0-0.9-0.30.3
LgA late post infusion interval0.91.13.90.80.01.10.50.50.3-1.2-1.20.9-1.0-0.7-0.8-0.8-0.8-1.0-0.9-1.41.12.0-1.7
LgA early loading1.42.65.02.21.71.72.21.91.8-1.4-1.41.9-2.11.71.71.81.21.21.01.11.51.30.3
LgA late loading0.10.10.40.20.30.20.40.30.30.10.10.2-0.50.60.50.50.40.50.40.50.10.10.6
LgA early average infusions1.31.63.21.81.31.71.71.51.4-1.3-1.21.6-1.71.11.11.10.90.70.60.61.31.20.4
LgA late average infusions0.30.41.8-0.10.3-0.30.10.20.30.70.70.00.30.60.70.90.70.70.70.9-0.4-1.31.3
LgA early timeout0.40.51.31.10.40.91.00.80.6-0.5-0.51.0-1.00.20.10.4-0.2-0.2-0.2-0.11.10.7-0.5
LgA late timeout0.10.21.1-0.6-0.4-0.4-0.4-0.3-0.20.30.4-0.30.5-0.1-0.1-0.10.40.10.10.2-0.8-0.51.0
LgA early titration0.40.61.61.10.71.01.10.80.6-0.7-0.70.9-1.30.50.50.40.20.10.10.11.11.20.0
LgA late titration0.50.72.5-0.9-0.4-1.1-0.9-0.7-0.61.11.1-1.00.9-0.10.0-0.10.50.30.30.5-1.1-1.41.6
LgA total infusion0.50.71.30.91.00.91.11.00.9-0.5-0.41.0-1.00.90.91.10.60.60.50.70.80.10.8
Times rat made contact with spout3.13.59.91.6-0.31.81.30.6-0.0-1.7-1.71.3-2.3-1.4-1.5-1.3-2.0-2.2-2.3-2.32.73.1-2.8
Lifetime Intake0.30.30.8-0.6-0.6-0.7-0.8-0.5-0.50.90.9-0.60.6-0.6-0.5-0.6-0.2-0.3-0.2-0.3-0.6-0.7-0.1
Liver weight, left0.60.92.00.71.10.50.61.01.2-0.6-0.60.8-0.61.31.31.00.91.41.41.30.5-0.10.7
Liver weight, right1.42.44.71.21.51.11.01.71.9-1.3-1.31.4-0.81.92.01.82.22.02.11.80.2-0.21.5
Locomotor activity0.91.43.9-0.3-1.0-0.0-0.2-0.7-1.00.20.2-0.30.1-1.5-1.5-1.5-2.0-1.7-1.8-1.60.61.1-1.9
Locomotor testing distance0.40.71.9-1.0-0.7-1.1-0.8-0.9-0.91.41.4-0.90.9-0.5-0.5-0.5-0.8-0.3-0.4-0.1-0.8-0.6-0.5
Locomotor testing rearing1.32.64.6-1.5-1.9-1.3-1.3-1.8-1.91.41.4-1.41.2-2.0-2.0-1.9-2.1-1.8-1.9-1.7-0.60.2-1.7
Locomotion in novel chamber2.43.16.61.82.62.02.11.61.5-1.6-1.61.2-1.72.42.32.21.21.71.62.01.30.20.8
Locomotion in novel chamber post-restriction1.72.74.51.62.01.31.71.92.0-1.3-1.31.6-1.42.12.02.11.91.81.81.80.8-0.11.1
Fecal boli incidents, locomotor time 10.20.20.80.60.30.50.30.50.6-0.9-0.90.5-0.40.30.30.30.70.40.40.20.00.30.4
Change in fecal boli incidents, locomotor task0.70.62.0-0.5-0.6-0.0-0.0-0.2-0.40.20.20.1-0.0-1.0-1.0-0.9-1.4-1.1-1.1-1.10.80.9-1.4
Time >=10cm from walls, locomotor time 10.20.20.50.30.70.70.60.40.4-0.5-0.50.4-0.60.60.50.7-0.10.30.30.30.40.0-0.0
Bouts of movement, locomotor time 11.01.24.2-0.7-0.7-1.0-0.2-0.9-1.21.41.4-0.70.1-1.1-1.1-0.8-2.1-1.3-1.4-1.00.90.1-1.4
Total resting periods, locomotor time 10.50.51.8-0.2-0.4-0.60.1-0.4-0.70.90.9-0.2-0.2-0.7-0.7-0.5-1.3-0.9-1.0-0.80.90.3-1.1
Rest time, locomotor task time 10.10.10.30.40.10.20.20.30.30.20.20.4-0.5-0.0-0.0-0.10.10.00.0-0.10.60.4-0.1
Distance moved, locomotor task time 10.20.30.8-0.7-0.6-0.7-0.8-0.5-0.40.10.1-0.50.9-0.4-0.4-0.50.3-0.2-0.0-0.3-0.9-0.40.4
Vertical activity count, locomotor time 10.00.10.2-0.4-0.3-0.4-0.3-0.3-0.30.00.0-0.30.4-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.4-0.0-0.2
Time >=10cm from walls, locomotor time 20.91.32.90.31.30.30.51.01.3-0.2-0.20.7-0.31.41.51.61.71.61.61.6-0.5-1.11.6
Bouts of movement, locomotor time 21.52.47.5-1.7-0.7-2.2-1.5-0.9-0.41.91.9-1.32.00.40.50.61.21.21.21.4-1.9-2.72.1
Total resting periods, locomotor time 21.22.05.8-1.8-0.9-2.2-1.5-1.0-0.72.02.0-1.41.90.10.20.30.70.80.81.0-1.7-2.41.6
Rest time, locomotor task time 20.30.41.50.50.00.40.40.30.1-0.5-0.50.5-0.8-0.4-0.4-0.5-0.5-0.6-0.6-0.80.91.2-0.9
Distance moved, locomotor task time 20.20.20.50.10.60.20.30.50.6-0.2-0.20.3-0.00.70.70.70.50.70.70.70.0-0.30.4
Vertical activity count, locomotor time 20.30.41.10.50.90.50.50.50.6-0.3-0.30.3-0.41.01.00.80.60.90.91.00.1-0.20.6
Light reinforcement 10.20.41.0-0.8-0.6-0.9-0.7-0.6-0.40.90.9-0.60.9-0.2-0.1-0.20.20.10.10.2-1.0-0.61.0
Light reinforcement 21.21.95.7-0.90.2-1.3-0.9-0.30.11.31.3-0.81.31.21.21.01.71.71.81.9-1.9-2.41.8
Bone: marrow area0.00.10.5-0.40.2-0.7-0.1-0.1-0.10.30.3-0.20.40.10.10.10.00.10.10.2-0.3-0.40.1
Bone: maximum diameter2.44.57.0-2.6-2.6-2.4-2.4-2.5-2.52.22.2-2.42.5-2.3-2.2-2.1-1.2-1.8-1.7-1.7-2.1-1.4-0.0
Bone: maximum force0.10.30.9-0.6-0.4-0.9-0.6-0.5-0.50.60.6-0.50.6-0.5-0.4-0.4-0.2-0.3-0.3-0.3-0.5-0.40.1
Bone: maximum moment0.20.41.0-0.8-0.6-1.0-0.7-0.7-0.70.80.8-0.70.7-0.6-0.5-0.5-0.3-0.4-0.4-0.3-0.6-0.50.1
Mean time between licks in bursts0.20.51.1-0.5-0.8-0.2-0.4-0.6-0.70.30.3-0.40.6-1.0-1.0-0.7-0.2-1.0-1.0-1.0-0.4-0.10.7
Mean num. licks in bursts2.64.09.02.71.12.72.32.11.7-2.9-2.92.5-3.00.10.10.3-0.0-0.6-0.6-0.92.92.9-1.2
Cd content in liver0.70.71.8-0.5-1.2-0.3-0.6-0.7-0.80.20.2-0.40.5-1.3-1.3-1.0-0.8-1.2-1.2-1.4-0.30.2-0.9
Co content in liver1.01.11.7-1.2-1.2-1.0-1.0-1.3-1.31.31.3-1.21.1-1.0-1.0-0.9-1.1-0.9-0.9-0.8-0.9-0.4-0.8
Cu content in liver0.20.30.9-0.2-0.6-0.0-0.2-0.3-0.4-0.2-0.2-0.0-0.0-0.8-0.8-0.7-0.4-0.9-0.8-0.90.10.6-0.4
Fe content in liver1.21.42.51.11.61.11.21.31.4-1.1-1.11.1-0.91.61.61.41.01.41.41.40.60.30.4
K content in liver1.91.84.9-1.8-0.6-1.5-1.7-1.3-0.91.61.6-1.62.0-0.00.0-0.20.80.50.60.6-1.9-1.92.2
Mg content in liver0.30.30.9-0.8-0.5-0.6-0.7-0.8-0.70.70.7-0.81.0-0.2-0.2-0.3-0.1-0.1-0.1-0.1-0.7-0.50.7
Mn content in liver0.30.31.7-0.7-0.4-0.4-0.8-0.4-0.10.40.4-0.51.00.00.10.10.60.40.50.4-1.3-1.00.3
Na content in liver2.02.14.0-1.9-1.4-2.0-1.6-1.8-1.82.02.0-1.91.5-1.2-1.1-1.2-1.0-0.8-0.9-0.6-1.2-1.00.4
Rb content in liver0.80.91.8-1.2-1.4-0.8-1.2-1.0-1.00.50.5-0.91.2-1.2-1.2-1.3-0.6-0.9-0.8-1.1-0.7-0.00.2
Se content in liver0.91.02.3-1.4-1.1-1.0-1.5-1.3-1.11.21.2-1.41.4-0.6-0.6-0.8-0.2-0.2-0.1-0.2-1.3-0.90.6
Sr content in liver3.32.85.7-2.0-1.8-1.9-2.0-2.4-2.41.91.9-2.41.5-1.5-1.5-1.6-1.3-1.2-1.2-1.0-1.2-0.80.3
Zn content in liver0.60.73.0-0.9-0.4-0.4-1.1-0.6-0.20.40.4-0.71.20.00.1-0.10.90.50.60.4-1.5-1.01.7
Bone: minimum diameter0.10.20.5-0.20.3-0.20.00.30.4-0.2-0.20.20.30.40.50.50.60.50.60.4-0.5-0.40.7
Time in familiar zone, hab. session 10.10.10.2-0.10.2-0.30.10.10.10.20.20.00.30.20.20.30.20.20.20.3-0.5-0.50.1
Time in novel zone, hab. session 10.30.31.00.2-0.60.5-0.1-0.2-0.3-0.4-0.4-0.1-0.4-0.6-0.6-0.7-0.5-0.7-0.7-0.80.61.0-0.5
Total zone transitions, hab. session 10.00.10.40.00.10.2-0.10.10.2-0.4-0.40.10.00.10.10.10.60.20.20.2-0.3-0.30.4
Total locomotion distance, hab. session 10.70.93.0-0.9-0.1-1.0-0.7-0.4-0.20.90.9-0.71.20.60.60.71.00.90.91.1-1.5-1.71.4
Locomotion velocity, hab. session 10.40.62.0-0.60.1-0.8-0.3-0.20.10.70.7-0.40.80.70.70.80.90.90.91.1-1.0-1.41.1
Time in familiar zone, hab. session 21.01.01.51.21.11.21.21.21.2-1.2-1.21.2-1.01.01.01.00.60.70.70.61.10.70.1
Time in novel zone, hab. session 21.31.42.7-0.9-1.4-0.7-1.2-1.3-1.40.70.7-1.10.6-1.6-1.6-1.6-1.1-1.5-1.4-1.5-0.40.2-0.8
Total zone transitions, hab. session 20.50.71.8-1.1-0.7-0.9-1.3-0.8-0.50.80.8-1.01.2-0.3-0.2-0.30.50.20.30.2-1.3-1.21.2
Total locomotion distance, hab. session 20.71.02.3-1.4-1.0-1.3-1.5-1.1-0.81.11.1-1.31.5-0.5-0.4-0.50.00.10.10.1-1.2-1.00.9
Locomotion velocity, hab. session 21.21.63.6-1.7-1.1-1.7-1.8-1.3-0.91.51.5-1.51.9-0.4-0.3-0.40.20.30.40.4-1.7-1.71.3
Novel to familiar place preference ratio0.20.20.5-0.1-0.5-0.0-0.2-0.2-0.3-0.0-0.0-0.1-0.0-0.7-0.7-0.6-0.3-0.7-0.7-0.70.10.1-0.4
Novelty place preference0.20.20.70.0-0.50.2-0.1-0.1-0.3-0.2-0.20.0-0.1-0.7-0.7-0.6-0.4-0.8-0.7-0.80.30.3-0.4
Time in novel zone, NPP test0.30.31.00.1-0.50.4-0.0-0.1-0.3-0.3-0.30.1-0.3-0.8-0.8-0.8-0.6-0.9-0.9-1.00.50.5-0.7
Total zone transitions, NPP test0.71.02.7-0.00.8-0.0-0.10.30.7-0.0-0.0-0.00.21.31.31.31.41.51.51.5-0.8-1.21.7
Total locomotion distance, NPP test0.91.23.3-0.60.4-0.9-0.6-0.10.20.90.9-0.60.91.11.21.11.31.61.51.6-1.2-1.61.8
Locomotion velocity, NPP test1.01.43.7-0.90.2-1.1-0.8-0.30.11.11.1-0.81.21.01.11.01.21.51.51.6-1.4-1.81.9
Intraocular pressure0.30.41.0-0.6-0.7-0.0-0.6-0.7-0.70.40.4-0.61.0-0.8-0.8-0.7-1.0-0.6-0.6-0.6-0.7-0.1-0.8
Delta distance traveled before/after self-admin0.80.81.80.60.80.70.40.70.9-0.2-0.20.4-0.41.21.21.11.41.31.31.30.1-0.61.3
Delta ambulatory time before/after self-admin0.60.81.80.70.80.80.40.70.8-0.3-0.30.4-0.61.21.20.91.31.21.21.30.2-0.31.2
Parametrial fat weight1.43.47.3-1.5-2.2-1.7-1.8-1.6-1.81.21.2-1.30.8-2.6-2.6-2.7-2.0-2.2-2.1-2.5-0.10.7-1.4
Pavlov. Cond. lever latency0.20.30.8-0.1-0.40.2-0.0-0.3-0.50.00.0-0.10.0-0.7-0.8-0.6-0.7-0.9-0.9-0.90.50.4-0.8
Pavlov. Cond. magazine entry latency1.01.32.11.31.40.91.41.41.4-1.0-1.01.4-1.01.31.31.41.01.11.01.10.60.20.2
Pavlov. Cond. change in total contacts1.11.21.9-1.3-1.4-1.2-1.4-1.3-1.21.01.0-1.21.3-1.3-1.2-1.3-0.7-0.9-0.8-0.9-1.2-0.5-0.1
Pavlov. Cond. index score0.81.11.80.91.30.60.91.21.3-0.7-0.71.0-0.61.31.31.31.21.31.31.30.1-0.20.7
Pavlov. Cond. latency score0.81.01.70.81.20.50.81.11.2-0.7-0.70.9-0.51.31.31.31.21.31.31.30.1-0.20.8
Pavlov. Cond. lever contacts0.40.41.10.30.60.10.20.60.8-0.2-0.20.4-0.10.90.90.80.91.01.11.0-0.4-0.40.8
Pavlov. Cond. magazine entry number0.81.02.0-1.3-1.2-0.9-1.3-1.4-1.31.11.1-1.41.0-0.9-0.9-1.1-0.7-0.6-0.6-0.6-0.8-0.50.1
Pavlov. Cond. intertrial magazine entries1.41.74.1-1.3-0.2-2.0-1.3-0.7-0.31.81.8-1.21.30.70.80.50.81.41.41.6-1.7-1.91.2
Pavlov. Cond. lever-magazine prob. diff.1.11.32.21.01.40.61.01.31.4-0.8-0.81.1-0.61.51.51.51.31.41.41.40.1-0.20.8
Pavlov. Cond. response bias0.30.40.80.40.60.10.40.70.8-0.3-0.30.5-0.10.70.80.90.90.80.80.8-0.3-0.40.6
Pavlov. Cond. lever latency2.23.07.0-2.4-1.8-1.8-2.5-2.2-1.81.81.8-2.42.6-1.0-0.9-1.2-0.2-0.3-0.2-0.2-2.4-1.71.3
Pavlov. Cond. magazine entry latency0.00.00.20.00.4-0.30.40.20.10.10.10.2-0.20.20.20.3-0.00.10.00.20.2-0.1-0.1
Pavlov. Cond. change in total contacts0.10.20.60.60.60.20.70.70.6-0.3-0.30.7-0.70.30.30.40.40.20.20.20.60.3-0.1
Pavlov. Cond. index score0.60.92.01.21.20.71.41.21.1-0.8-0.81.3-1.40.70.70.80.30.30.20.41.30.7-0.5
Pavlov. Cond. latency score0.71.02.11.21.30.61.41.31.2-0.7-0.71.3-1.40.90.91.00.60.60.50.61.20.6-0.3
Pavlov. Cond. lever contacts2.33.26.82.42.01.92.62.32.0-2.0-2.02.5-2.61.21.11.40.50.50.40.42.21.6-1.1
Pavlov. Cond. magazine entry number0.50.61.8-0.6-0.2-0.4-0.8-0.5-0.10.60.6-0.71.00.40.50.30.70.80.80.8-1.3-1.21.1
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.3-0.50.1-0.4-0.4-0.3-0.1-0.1-0.30.4-0.2-0.2-0.2-0.2-0.1-0.1-0.1-0.4-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.81.12.51.31.30.81.51.31.1-0.9-0.91.4-1.60.80.80.90.40.40.30.41.40.8-0.5
Pavlov. Cond. response bias1.41.84.41.81.41.32.01.71.3-1.5-1.51.9-2.10.60.50.8-0.1-0.0-0.1-0.02.01.5-1.3
LgA PC1 addiction-like behavior0.10.31.70.50.50.50.40.30.3-0.2-0.10.2-0.50.60.60.60.80.50.50.60.20.01.3
Time in closed arm before self-admin0.10.20.7-0.5-0.6-0.8-0.5-0.4-0.30.60.6-0.40.0-0.3-0.3-0.7-0.1-0.1-0.1-0.1-0.30.30.1
Time in closed arm after self-admin2.02.23.71.31.51.11.21.61.8-0.9-0.91.4-1.31.91.91.61.91.91.91.80.50.11.3
Time in open arm before self-admin0.80.91.71.11.10.70.80.90.9-0.2-0.20.6-0.61.31.31.31.11.11.11.30.4-0.50.6
Time in open arm after self-admin0.50.61.4-0.6-0.6-0.7-0.5-0.6-0.70.30.3-0.30.9-1.2-1.1-0.7-1.0-1.1-1.0-1.2-0.2-0.3-0.9
Bone: periosteal estimation0.40.92.3-1.3-0.7-1.5-1.1-1.0-0.91.21.2-1.11.3-0.5-0.5-0.4-0.1-0.2-0.2-0.1-1.3-1.10.5
Bone: periosteal perimeter1.32.25.2-2.1-1.3-2.1-1.8-1.6-1.41.81.8-1.82.3-0.5-0.5-0.40.1-0.00.00.1-2.2-2.01.3
Bone: post-yield work0.10.10.7-0.4-0.1-0.8-0.1-0.3-0.20.60.6-0.30.30.10.10.20.20.10.10.2-0.5-0.60.3
Progressive ratio test 1 active lever presses0.30.41.5-0.7-0.4-0.8-0.9-0.3-0.20.90.9-0.50.6-0.1-0.0-0.20.50.30.50.3-0.9-1.20.6
Progressive ratio test 1 breakpoint0.40.41.8-0.8-0.5-0.9-0.9-0.3-0.20.90.9-0.60.7-0.1-0.0-0.20.50.40.50.3-0.9-1.30.6
Progressive ratio test 1 inactive lever presses2.53.67.2-2.3-2.3-2.6-2.7-1.7-1.42.42.4-1.92.5-1.4-1.2-1.30.5-0.3-0.1-0.5-2.5-2.61.5
Progressive ratio test 2 active lever presses0.50.61.6-0.8-0.6-1.0-0.7-0.8-0.91.31.3-0.90.7-0.6-0.6-0.4-0.8-0.5-0.5-0.3-0.3-1.0-0.3
Progressive ratio test 2 breakpoint0.40.51.3-0.7-0.6-0.9-0.6-0.8-0.91.11.1-0.80.6-0.6-0.5-0.4-0.9-0.5-0.5-0.3-0.2-0.8-0.4
Progressive ratio test 2 inactive lever presses0.81.23.0-1.3-1.3-1.5-1.5-1.0-0.81.71.7-1.11.3-0.7-0.7-0.60.2-0.2-0.1-0.3-1.3-1.70.9
ShA PR total presses3.33.86.12.52.32.32.42.12.1-1.5-1.51.9-2.32.42.32.31.71.71.61.71.50.60.8
Incentive Sensitization - Responses0.40.61.3-0.6-0.7-0.9-0.5-1.0-1.11.11.1-1.00.5-0.5-0.6-0.5-1.1-0.7-0.8-0.4-0.2-0.1-0.6
Incentive Sensitization - Breakpoint0.40.61.6-0.5-0.6-0.8-0.3-1.0-1.11.01.0-0.90.4-0.5-0.6-0.4-1.3-0.7-0.8-0.50.0-0.0-0.8
LgA PR total presses1.11.23.81.21.01.91.41.10.9-1.5-1.41.2-1.70.60.50.50.20.10.0-0.01.31.40.1
Sum of active levers in priming session hrs 5-60.40.41.1-0.8-0.6-0.7-0.9-0.9-0.80.60.6-1.10.8-0.2-0.3-0.50.2-0.1-0.0-0.0-0.8-0.70.8
Progressive ratio0.30.41.40.20.60.40.10.70.8-0.6-0.60.4-0.20.70.80.41.20.91.00.7-0.3-0.20.8
Food seeking constrained by brief footshock2.42.96.7-2.1-1.3-2.1-2.2-1.6-1.22.32.3-2.02.3-0.3-0.2-0.50.90.50.70.5-2.6-2.42.0
Seeking ratio, punishment vs. effort1.21.74.3-1.5-1.4-1.9-1.5-1.4-1.22.12.1-1.51.8-0.7-0.6-0.4-0.2-0.1-0.20.1-1.5-1.60.8
Retroperitoneal fat weight0.52.13.2-1.6-1.8-1.8-1.6-1.6-1.61.61.6-1.41.2-1.7-1.7-1.5-1.4-1.4-1.4-1.5-0.8-0.4-0.6
Reaction time number correct0.10.20.70.1-0.30.30.1-0.1-0.3-0.3-0.30.10.1-0.6-0.7-0.4-0.3-0.8-0.8-0.80.40.2-0.2
Reaction time mean minus median0.92.26.01.91.42.42.01.51.1-2.0-2.01.7-2.10.60.50.6-0.1-0.2-0.3-0.22.11.9-0.7
Reaction time mean minus median AUC0.61.53.51.71.41.91.81.20.9-1.5-1.51.4-1.80.60.50.7-0.1-0.1-0.20.01.81.4-0.6
Reaction time num false alarms0.81.12.4-1.4-1.3-1.1-1.2-1.4-1.21.61.6-1.41.3-0.5-0.5-0.5-0.6-0.2-0.3-0.1-1.0-0.90.4
Reaction time num false alarms AUC0.71.22.7-1.4-1.1-1.2-1.3-1.4-1.21.61.6-1.61.4-0.1-0.1-0.3-0.40.10.10.4-1.2-1.20.7
Reaction time trials correct on left0.10.20.70.1-0.30.30.1-0.1-0.3-0.3-0.30.10.1-0.6-0.7-0.4-0.3-0.8-0.8-0.80.40.2-0.2
Reaction time trials on left0.10.20.70.1-0.30.40.2-0.1-0.3-0.4-0.40.10.0-0.6-0.6-0.4-0.3-0.8-0.8-0.80.40.3-0.2
Reaction time mean0.60.92.61.21.31.61.01.00.9-1.2-1.20.9-1.30.90.80.60.50.60.60.50.70.7-0.2
Reaction time mean AUC0.81.33.01.41.61.71.21.21.2-1.3-1.31.1-1.41.21.21.00.90.90.90.80.80.60.2
Median of all reaction times0.40.61.50.91.21.20.60.90.9-0.9-0.90.6-0.90.90.80.60.70.80.90.70.20.30.1
Reaction time omissions0.71.02.61.31.21.61.20.90.8-1.2-1.20.9-1.60.80.70.70.10.30.30.41.20.9-0.7
Reaction time false alarm rate0.91.23.0-1.4-0.9-1.3-1.3-1.3-1.01.71.7-1.61.30.20.2-0.1-0.30.50.50.7-1.3-1.30.8
Reaction time premature initiation rate2.12.84.91.82.01.31.62.12.2-1.5-1.51.8-1.32.02.12.01.81.91.91.80.70.10.5
Reaction time premature initiations0.81.52.61.51.41.31.41.61.6-1.4-1.41.5-1.11.21.21.31.21.01.00.90.80.30.0
Std. dev. reaction times0.81.54.31.61.32.11.61.20.9-1.6-1.61.2-1.80.80.70.70.00.10.00.11.61.4-0.5
Reaction time trials completed0.10.20.70.1-0.30.40.2-0.1-0.3-0.4-0.40.10.0-0.6-0.6-0.4-0.3-0.8-0.8-0.80.40.3-0.2
Reaction time trials AUC0.10.20.6-0.0-0.30.30.0-0.2-0.3-0.2-0.20.00.2-0.6-0.7-0.4-0.2-0.8-0.8-0.80.20.1-0.0
Run reversals in cocaine runway, females0.70.72.0-0.00.9-0.20.30.30.30.70.7-0.10.11.11.21.20.71.11.11.4-0.1-1.31.0
Run reversals in cocaine runway, males0.10.10.3-0.2-0.40.0-0.3-0.2-0.20.30.3-0.10.2-0.6-0.5-0.5-0.1-0.4-0.4-0.5-0.10.10.2
Latency to leave start box in cocaine runway0.40.41.1-0.8-0.5-0.8-0.8-1.0-0.80.80.8-1.10.8-0.2-0.3-0.5-0.3-0.1-0.10.0-0.9-0.2-0.1
Latency to leave start box in cocaine runway, F1.31.43.5-1.6-1.0-1.5-1.4-1.7-1.61.71.7-1.91.2-0.5-0.5-0.8-0.9-0.3-0.4-0.0-1.2-0.9-0.0
Latency to leave start box in cocaine runway, M0.30.30.91.00.50.60.30.60.7-0.9-0.90.7-0.20.30.30.30.80.30.40.10.00.7-0.1
Std. dev. time between licks in bursts0.10.10.5-0.4-0.3-0.70.0-0.2-0.20.60.6-0.10.5-0.2-0.20.10.1-0.2-0.3-0.1-0.2-0.50.7
Total sessions with >9 infusions1.01.32.41.31.20.91.11.51.6-1.0-1.01.4-1.21.21.21.11.41.11.21.00.60.20.4
Short access day 1 total inactive lever presses1.52.04.7-1.7-1.5-1.6-1.9-1.4-1.31.41.4-1.42.2-1.6-1.5-1.3-0.4-1.0-0.8-1.1-1.6-1.40.3
Short access day 10 total inactive lever presses0.10.21.0-0.3-0.3-0.3-0.50.20.30.20.20.20.7-0.3-0.20.10.50.20.3-0.1-0.6-1.00.2
Short access day 1 total infusions1.01.43.81.11.11.00.81.51.6-1.1-1.11.3-0.71.11.21.32.01.31.41.00.1-0.41.2
Short access day 10 total infusions0.40.61.10.70.50.20.50.80.9-0.1-0.10.6-0.61.01.01.01.01.01.01.10.1-0.60.5
Short access total infusions0.10.10.50.40.20.10.10.50.5-0.2-0.20.4-0.20.30.30.20.70.40.50.3-0.1-0.20.3
ShA early post infusion interval1.01.02.8-1.1-1.3-1.7-1.1-1.1-1.11.11.1-1.20.9-0.9-0.9-1.0-0.9-0.7-0.7-0.5-0.7-0.5-0.5
ShA late post infusion interval0.30.31.1-0.5-0.2-0.8-0.5-0.10.10.10.1-0.30.60.30.30.20.80.60.70.6-0.8-1.10.9
ShA early loading0.50.51.10.80.80.81.00.90.9-0.8-0.81.0-0.80.80.80.90.50.50.50.50.50.20.1
ShA late loading2.43.36.82.42.02.62.52.22.0-1.9-1.92.4-2.51.31.21.40.50.50.40.32.21.9-0.4
Short access day 1 locomotion1.82.37.41.11.20.80.61.41.7-1.0-1.01.1-0.51.71.81.72.72.02.11.8-0.4-0.82.1
Short access day 10 total locomotion1.93.511.41.11.61.20.82.12.4-1.3-1.31.6-0.82.02.11.83.42.42.62.1-0.3-1.02.4
Short access total locomotion2.02.55.71.41.51.31.12.02.2-1.5-1.51.8-1.21.61.71.52.41.81.91.50.30.11.3
ShA early average infusions0.30.41.40.70.61.20.70.70.6-0.7-0.70.7-0.70.40.40.30.30.20.20.00.60.9-0.2
ShA late average infusions2.52.64.11.91.81.91.81.81.8-0.9-0.91.6-1.72.01.91.91.91.61.61.50.90.61.3
ShA early timeout0.20.20.80.30.00.90.30.10.1-0.7-0.70.4-0.3-0.3-0.4-0.2-0.3-0.6-0.6-0.70.40.8-0.4
ShA late timeout1.01.11.91.31.11.21.31.11.1-0.4-0.31.0-1.21.41.31.30.91.11.01.10.70.40.5
ShA early titration0.30.31.40.60.61.20.70.60.6-0.8-0.80.7-0.60.40.30.40.30.20.10.10.40.50.2
ShA late titration2.62.75.22.02.02.31.91.91.9-1.6-1.61.8-2.01.71.71.61.51.31.21.11.11.10.8
ShA total infusions2.63.24.82.12.12.22.12.02.1-1.2-1.21.9-2.02.12.02.01.81.61.61.51.10.81.1
One hour access (0.3 mA shock)0.50.61.3-0.9-0.9-0.9-1.0-0.6-0.61.11.1-0.81.0-0.5-0.5-0.60.1-0.1-0.0-0.2-0.8-1.10.6
Shock compulsivity0.51.02.50.50.90.30.40.40.6-0.1-0.00.1-0.21.51.51.31.31.41.41.6-0.2-1.01.3
Compulsive drug intake0.91.12.21.21.11.31.41.01.0-1.1-1.10.9-1.01.41.31.50.60.90.81.10.90.20.1
One hour access (shock baseline)0.30.51.1-0.9-0.7-0.9-1.0-0.6-0.61.01.0-0.70.7-0.8-0.7-0.9-0.1-0.5-0.3-0.6-0.7-0.70.3
Social response proportion0.50.61.5-0.9-1.0-0.8-1.2-0.8-0.70.70.7-0.80.6-0.9-0.8-1.0-0.1-0.5-0.4-0.6-0.5-0.20.4
Social responses1.62.14.5-1.5-1.9-1.1-1.6-1.5-1.51.11.1-1.21.0-1.9-1.9-2.1-1.4-1.6-1.5-1.7-0.40.6-0.0
Social time0.20.30.9-0.3-0.60.2-0.5-0.4-0.5-0.2-0.2-0.3-0.1-0.8-0.9-0.8-0.5-0.8-0.7-1.00.20.70.3
Soleus weight0.82.35.6-2.0-1.3-1.7-1.9-1.6-1.22.12.1-1.82.1-0.3-0.2-0.30.30.30.40.4-2.4-2.11.8
Bone: stiffness0.00.10.30.20.2-0.30.40.40.50.00.00.5-0.20.20.20.30.10.20.20.20.20.1-0.2
Tibialis anterior weight0.93.25.1-1.9-2.2-2.0-1.8-2.2-2.22.12.1-2.01.3-1.9-1.9-2.0-1.6-1.7-1.7-1.6-1.0-0.4-0.7
Time to tail flick, vehicle, before self-admin0.80.83.9-0.20.0-0.1-0.60.20.40.20.2-0.20.50.60.70.41.91.11.20.9-1.2-1.22.0
Time to tail flick, vehicle, after self-admin0.20.21.0-0.40.50.2-0.20.00.10.20.2-0.20.20.50.50.20.60.60.70.6-0.4-0.51.0
Time to tail flick, test, before self-admin0.50.51.40.70.30.90.70.40.2-0.9-0.90.6-0.8-0.2-0.2-0.1-0.8-0.5-0.6-0.51.01.2-1.2
Time to tail flick, test, after self-admin2.02.14.4-1.8-1.6-1.9-2.1-1.5-1.21.61.6-1.72.0-1.0-0.9-0.80.2-0.2-0.1-0.1-2.1-2.11.0
Delta time to tail flick, vehicle, before/after SA0.10.10.40.00.70.20.40.20.20.00.00.1-0.40.60.60.5-0.00.50.40.60.3-0.00.2
Delta time to tail flick, test, before/after SA1.41.43.0-1.5-1.2-1.6-1.7-1.1-0.91.41.4-1.21.7-0.8-0.7-0.70.3-0.10.0-0.2-1.7-1.61.0
Tibia length0.51.33.0-0.60.9-1.1-0.20.00.31.01.0-0.41.01.31.31.31.21.51.51.7-1.3-1.71.5
Ambulatory time before self-admin0.30.51.3-0.9-0.5-0.8-0.6-0.7-0.80.70.7-0.71.0-0.7-0.6-0.2-0.8-0.6-0.6-0.5-0.5-1.2-0.4
Ambulatory time after self-admin0.30.32.3-0.10.2-0.1-0.20.10.20.10.1-0.20.50.40.50.70.80.60.70.7-0.5-1.50.9
Bone: tissue strength0.90.92.50.7-0.20.70.70.3-0.0-0.9-0.90.6-0.8-0.8-0.8-0.7-1.1-1.2-1.2-1.21.21.5-1.6
Total heroin consumption0.10.10.50.30.10.40.00.20.1-0.7-0.70.1-0.30.0-0.0-0.30.5-0.10.0-0.20.20.50.3
Total infusions0.70.91.71.11.11.11.31.11.0-0.6-0.51.1-1.21.00.91.20.70.60.60.71.00.30.8
Bone: trabecular number0.00.00.10.20.2-0.00.10.10.10.10.10.1-0.30.10.10.10.30.10.10.10.0-0.00.0
Bone: trabecular spacing0.60.91.5-1.2-1.2-1.2-1.0-1.1-1.11.21.2-1.11.0-0.8-0.8-0.8-0.6-0.6-0.6-0.5-0.7-0.70.1
Bone: trabecular thickness0.81.02.40.51.30.00.60.81.0-0.0-0.00.5-0.41.41.51.31.11.51.51.5-0.1-0.60.9
Bone: trabecular tissue density0.50.71.91.00.71.11.00.80.6-1.3-1.30.9-1.30.20.20.3-0.2-0.1-0.2-0.11.41.1-0.7
Water consumed over 24 hours1.11.53.6-0.3-1.3-0.2-0.4-0.8-1.00.20.2-0.4-0.2-1.7-1.7-1.5-1.7-1.8-1.8-1.80.71.0-1.9
Number of responses in last shaping day0.40.51.60.10.1-0.2-0.00.40.60.00.00.30.30.60.60.91.30.80.90.8-0.5-1.21.2