Hub : Genes

Odad2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XM_063276478.1 0.03 0.02 4.7e-03 0.01 0.03 0.02 0.02 2.3e-02 4.1e-03 7.0e-03 1.7e-02
2 pVTA alternative polyA XM_063276478.1 0.03 0.02 4.2e-03 0.01 0.03 0.02 0.02 3.4e-02 3.2e-03 7.5e-03 1.6e-02
3 Brain gene expression Odad2 0.05 0.03 2.6e-04 0.04 0.04 0.03 0.03 3.1e-04 8.4e-05 1.1e-03 1.1e-03
4 pVTA alternative polyA XM_063276478.1 0.05 0.03 3.1e-04 0.02 0.03 0.03 0.02 8.9e-03 1.9e-03 1.6e-03 4.6e-03
5 pVTA gene expression Odad2 0.22 0.1 9.6e-13 0.12 0.15 0.13 0.15 1.3e-09 3.1e-12 1.9e-10 4.9e-12
6 Brain alternative polyA XM_063276478.1 0.03 0.02 8.8e-03 0.01 0 0 0 6.3e-02 1.9e-01 3.0e-01 1.2e-01
7 PL alternative polyA NM_001427763.1 0.03 0.02 7.9e-03 0 0 -0 -0 2.1e-01 1.5e-01 4.9e-01 3.9e-01
8 PL alternative polyA XM_063276478.1 0.05 0.04 6.9e-04 0.01 0.01 0.01 0.01 7.3e-03 4.7e-02 1.3e-02 1.5e-02
9 PL gene expression Odad2 0.09 0.04 1.4e-10 0.09 0.1 0.1 0.1 6.4e-10 9.6e-11 1.8e-11 3.7e-11
10 Brain alternative polyA XM_063276478.1 0.03 0.02 2.9e-03 0.01 0.02 0.01 0.02 1.6e-02 6.1e-03 2.2e-02 1.1e-02
11 Brain isoform ratio XM_063276478.1 0.06 0.04 1.3e-04 0.04 0.05 0.07 0.05 2.0e-04 3.4e-05 3.0e-07 1.5e-05
12 Brain mRNA stability Odad2 0.1 0.05 6.2e-04 0.02 0.03 0.03 0.02 6.1e-03 7.0e-04 1.8e-03 2.4e-03
13 NAcc gene expression Odad2 0.04 0.03 5.8e-04 0.01 0.02 0.02 0.01 2.2e-02 6.8e-04 5.6e-04 3.6e-03
14 PL alternative polyA XM_063276478.1 0.04 0.03 1.6e-04 0.03 0.02 0.02 0.03 2.2e-04 5.2e-03 1.6e-03 2.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.20.41.10.80.9-0.80.8-0.80.4-0.71.0-0.50.3-0.10.5-0.50.0
Area under the delay curve2.02.35.21.21.6-1.61.9-2.30.0-2.31.7-1.8-0.4-0.31.8-1.60.0
BMI with tail0.20.71.7-1.2-1.11.3-1.20.7-1.10.9-0.60.4-1.0-0.3-0.4-0.30.0
BMI without tail0.20.72.31.10.6-1.00.20.11.5-0.20.20.21.51.3-0.21.00.0
Body weight0.52.05.72.01.4-1.60.6-0.32.4-0.41.1-0.22.32.4-0.51.10.0
Weight adjusted by age2.13.29.92.12.3-1.92.0-2.01.2-1.93.1-1.90.70.40.7-1.61.4
Bone surface1.52.76.32.42.2-1.51.5-0.72.2-0.31.6-0.52.32.5-1.40.90.0
Bone volume0.61.22.81.61.4-1.10.7-0.41.6-0.21.2-0.21.71.4-0.80.60.0
Breakpoint value in progressive ratio session0.20.20.50.10.5-0.10.6-0.7-0.4-0.50.1-0.7-0.6-0.50.4-0.5-0.4
Number of licking bursts0.20.31.0-0.4-0.90.2-1.00.80.10.4-0.30.70.1-0.40.40.40.0
Context. condit. distance diff. score0.81.02.2-1.5-1.41.3-1.00.8-1.30.8-1.20.6-1.1-1.1-0.20.00.0
Locomotion velocity, session 10.70.71.3-1.0-1.01.1-1.01.1-0.51.2-0.70.7-0.3-0.8-1.00.20.0
Locomotion distance, session 10.81.03.7-1.3-0.81.1-0.60.1-1.60.1-0.1-0.5-1.9-1.10.8-1.60.0
Locomotion velocity, session 20.30.41.10.70.9-0.61.1-0.60.4-0.50.9-0.90.20.30.1-0.40.0
Locomotion distance, session 20.50.72.7-0.10.2-0.10.3-0.8-0.8-0.80.9-1.0-1.2-0.31.3-1.60.0
Locomotion velocity, session 30.20.20.4-0.5-0.50.4-0.60.4-0.40.5-0.40.5-0.3-0.7-0.00.10.0
Locomotion distance, session 30.10.10.5-0.2-0.40.3-0.70.4-0.20.5-0.00.60.0-0.3-0.20.30.0
Stereotopy head waving bouts, day 30.60.72.81.20.7-1.20.4-0.31.7-0.50.60.21.50.50.10.60.0
Stereotopy head waving duration, day 30.70.82.31.10.9-0.60.60.01.40.10.20.21.51.0-1.31.00.0
Locomotion velocity, session 70.20.20.50.10.3-0.10.4-0.5-0.4-0.40.6-0.7-0.6-0.10.6-0.70.0
Locomotion distance, session 70.20.31.2-0.6-0.20.9-0.20.1-1.10.5-0.1-0.1-0.90.3-0.6-0.30.0
Stereotopy head waving bouts, day 70.91.02.21.51.3-1.11.0-0.71.4-0.61.1-0.61.31.1-0.40.30.0
Stereotopy head waving duration, day 70.50.61.51.11.0-0.90.8-0.51.2-0.40.7-0.51.11.0-0.40.30.0
Locomotion velocity, session 80.30.31.00.20.60.10.8-0.6-0.4-0.30.8-1.0-0.6-0.0-0.2-0.90.0
Locomotion distance, session 80.71.02.7-1.4-1.11.1-0.70.3-1.60.3-0.6-0.0-1.6-1.40.7-0.90.0
Degree of sensitization distance0.30.31.3-0.5-0.20.8-0.00.3-0.70.6-0.30.0-0.40.4-1.10.10.0
Degree of sensitization stereotypy0.70.81.61.31.1-0.90.8-0.51.3-0.41.0-0.51.20.9-0.60.30.0
Conditioned locomotion0.30.41.4-0.2-0.30.3-0.30.70.50.7-0.10.60.6-1.2-1.10.50.0
Cocaine response after cond. corrected0.40.51.50.51.0-0.21.0-1.0-0.2-0.70.7-1.2-0.40.2-0.1-0.80.0
Cocaine response after cond. not corrected0.40.51.30.81.2-0.41.0-0.90.2-0.50.7-1.00.10.9-0.5-0.20.0
Cocaine response before conditioning0.30.31.40.80.6-0.70.3-0.40.4-0.30.30.00.71.20.00.60.0
Saline control response0.71.03.01.10.7-0.50.00.51.50.50.60.51.71.3-1.41.30.0
Bone: connectivity density0.91.43.41.61.8-1.31.8-1.50.8-1.21.5-1.20.60.80.2-0.60.0
Bone: cortical apparent density0.20.31.80.50.8-0.00.5-0.30.30.00.7-0.60.31.4-0.8-0.10.0
Bone: cortical area0.50.82.3-0.5-0.60.8-0.51.1-0.31.3-1.11.10.40.2-1.51.50.0
Bone: cortical porosity0.60.62.11.10.7-1.30.5-0.41.5-0.60.4-0.21.20.10.60.50.0
Bone: cortical porosity0.40.41.70.80.3-1.10.2-0.11.3-0.4-0.00.21.1-0.20.70.60.0
Bone: cortical thickness0.91.63.5-1.0-1.31.4-1.31.7-0.71.9-1.21.40.10.0-1.51.60.0
Bone: cortical thickness0.50.62.40.2-0.30.1-0.61.00.50.9-0.20.70.91.6-0.61.40.0
Bone: cortical tissue density0.30.42.10.70.9-0.20.6-0.40.4-0.10.8-0.70.31.4-0.8-0.20.0
Condit. Reinf. active minus inactive responses0.60.71.91.20.9-0.90.5-0.31.3-0.20.30.01.41.0-0.60.90.0
Condit. Reinf. active-inactive response ratio0.20.20.50.50.5-0.40.4-0.10.7-0.0-0.30.00.70.4-0.60.60.0
Condit. Reinf. active responses1.62.04.82.21.9-1.81.3-0.82.2-0.81.2-0.62.01.7-0.30.70.0
Condit. Reinf. inactive responses1.01.22.91.61.5-1.20.9-0.61.5-0.61.4-0.71.31.7-0.20.20.0
Incentive salience index mean1.41.73.71.91.8-1.81.4-1.21.7-1.31.2-0.91.41.40.40.10.0
Condit. Reinf. lever presses3.95.59.82.73.1-2.73.1-2.91.5-2.82.7-2.70.72.11.6-1.50.0
Condit. Reinf. active minus inactive responses1.11.44.50.90.2-0.2-0.71.11.61.10.51.12.10.7-1.91.70.0
Condit. Reinf. active-inactive response ratio1.61.95.70.1-0.50.6-1.41.71.11.8-0.61.61.70.7-2.42.10.0
Condit. Reinf. active responses0.81.14.31.20.6-0.8-0.30.61.90.31.50.62.10.2-1.01.00.0
Condit. Reinf. inactive responses0.70.92.61.20.8-1.50.5-0.61.3-1.01.6-0.41.0-0.21.1-0.40.0
Condit. Reinf. lever presses0.91.22.9-0.9-1.31.0-1.51.70.11.5-0.21.40.3-1.5-1.10.70.0
Condit. Reinf. lever reinforcers received0.60.93.30.80.2-0.4-0.60.91.60.61.30.71.8-0.2-1.10.90.0
Conditioned reinforcement - actives0.20.41.1-0.2-0.80.1-0.60.90.50.6-0.51.00.70.4-0.01.0-0.3
Conditioned reinforcement - inactives3.75.410.0-2.8-3.22.7-3.02.8-1.72.7-1.92.6-0.9-1.7-1.31.0-2.4
Conditioned locomotion0.70.92.9-1.0-1.60.5-1.01.1-0.30.6-1.71.2-0.10.20.81.1-0.0
Patch foraging indifference point 0 sec0.10.10.5-0.3-0.10.30.0-0.0-0.50.1-0.70.1-0.30.0-0.20.50.0
Patch foraging indifference point AUC0.81.25.11.31.5-0.91.1-1.10.6-0.82.3-1.20.40.7-0.1-1.00.0
Delay disc. indifference point, 0s delay2.22.55.51.71.7-2.21.5-2.11.0-2.31.7-1.40.50.22.1-1.10.0
Delay disc. indifference point, 16s delay0.50.51.20.80.9-1.01.1-0.90.4-1.01.1-0.50.4-0.20.4-0.50.0
Delay disc. indifference point, 2s delay1.61.86.30.50.8-1.21.0-1.9-0.3-2.11.0-1.4-0.9-0.42.5-1.70.0
Delay disc. indifference point, 24s delay0.50.61.60.81.0-0.91.2-1.00.2-1.00.9-0.90.1-0.10.5-0.60.0
Delay disc. indifference point, 4s delay2.82.97.01.21.7-1.71.9-2.7-0.0-2.61.4-2.2-0.80.12.3-2.00.0
Delay disc. indifference point, 8s delay1.51.83.41.41.7-1.51.8-1.80.4-1.81.6-1.60.10.31.1-1.00.0
Indifference point function ln k1.32.34.8-2.0-2.01.7-1.71.5-1.41.3-2.21.5-1.0-1.9-0.40.80.0
Indifference point function log k1.32.34.8-2.0-2.01.7-1.71.5-1.41.3-2.21.5-1.0-1.9-0.40.80.0
Patch foraging total patch changes 0 sec0.10.10.4-0.4-0.20.4-0.10.1-0.60.2-0.60.2-0.4-0.1-0.20.40.0
Patch foraging total patch changes 12 sec1.21.53.51.51.9-1.01.6-1.30.6-1.01.9-1.40.51.6-0.2-0.60.0
Patch foraging total patch changes 18 sec0.20.21.00.30.5-0.40.6-0.6-0.0-0.61.0-0.5-0.0-0.30.2-0.50.0
Patch foraging total patch changes 24 sec0.20.31.20.80.5-0.50.2-0.00.8-0.10.50.31.10.7-0.60.80.0
Patch foraging total patch changes 6 sec0.20.31.10.50.8-0.10.6-0.70.0-0.41.0-0.9-0.20.7-0.3-0.50.0
Patch foraging time to switch 0 sec0.51.02.51.41.2-1.61.2-0.81.5-1.00.3-0.61.21.10.50.30.0
Patch foraging water rate 0 sec0.30.51.9-0.4-0.50.8-1.01.0-0.11.10.21.00.3-0.1-1.40.60.0
Patch foraging water rate 12 sec0.20.41.1-0.9-0.40.9-0.30.0-1.00.2-0.30.3-1.0-0.8-0.3-0.40.0
Patch foraging water rate 18 sec0.20.31.0-0.1-0.40.3-0.70.70.30.6-0.21.00.6-0.2-0.70.80.0
Patch foraging water rate 24 sec0.40.62.6-0.9-0.30.90.1-0.2-1.30.10.10.1-1.2-1.6-0.6-0.70.0
Patch foraging water rate 6 sec0.40.61.2-0.7-0.61.0-0.60.7-0.71.0-0.91.0-0.2-0.6-1.10.80.0
Seeking ratio, delayed vs. immediate footshock1.31.53.01.51.6-1.11.4-1.30.8-0.91.7-1.50.41.50.4-0.51.4
Distance traveled before self-admin2.53.25.62.32.4-2.02.2-1.81.5-1.62.0-1.91.11.70.7-0.62.3
Distance traveled after self-admin0.91.12.81.31.4-1.11.3-1.10.6-0.91.7-1.20.50.40.3-0.61.1
Extensor digitorum longus weight0.31.13.71.30.8-0.90.40.21.60.2-0.30.31.71.9-0.81.50.0
Bone: elastic displacement0.20.30.8-0.3-0.70.3-0.90.80.20.6-0.50.70.30.2-0.20.50.0
Bone: elastic work0.91.23.1-1.0-1.01.4-1.21.5-0.61.8-0.81.0-0.10.1-1.70.90.0
Bone: endosteal estimation0.40.91.81.31.3-1.31.3-0.91.2-0.90.7-0.61.01.00.2-0.00.0
Bone: endosteal perimeter0.40.81.91.21.3-1.11.4-0.91.1-0.80.1-0.40.91.1-0.20.30.0
Epididymis fat weight0.30.94.11.10.4-1.10.10.22.0-0.10.30.62.00.6-0.51.00.0
Delta time in closed arm before/after self-admin0.60.62.10.90.3-0.90.30.21.4-0.1-0.30.41.50.30.11.3-0.4
Delta time in open arm before/after self-admin0.90.91.8-1.3-1.31.0-1.00.6-1.20.4-0.30.3-1.3-1.20.7-0.9-0.7
Diff in mean of infusions in LGA sessions0.10.10.5-0.30.00.50.1-0.2-0.70.2-0.6-0.1-0.6-0.2-0.2-0.1-0.5
Delay discount exponential model param2.12.45.4-1.1-1.61.5-1.92.30.12.3-1.61.90.50.3-1.81.70.0
Extinction: sum of active levers before priming2.83.15.02.02.1-2.12.0-2.11.1-2.21.9-2.00.50.51.8-1.21.6
Active lever presses in extinction session 60.40.40.90.70.7-0.80.7-0.80.4-0.80.9-0.60.2-0.30.7-0.50.2
Bone: final force1.52.54.5-1.8-2.11.8-2.02.1-1.12.0-1.51.8-0.4-1.3-1.01.20.0
Bone: final moment1.21.93.6-1.6-1.91.5-1.81.9-0.91.7-1.31.7-0.3-1.3-0.91.10.0
Food consumed during 24 hour testing period0.50.72.9-1.0-0.60.9-0.1-0.1-1.70.1-0.3-0.3-1.6-1.00.5-0.80.0
Glucose0.40.63.1-0.10.0-0.40.2-0.8-0.6-0.90.7-0.6-0.9-0.51.7-1.00.0
Heart weight1.52.35.0-1.4-1.51.8-1.81.9-0.82.2-1.71.7-0.00.2-2.11.70.0
Delay discount hyperbolic model param2.32.65.9-1.1-1.61.5-2.02.40.22.4-1.62.00.70.2-2.01.80.0
Intermittent access intake day 1-15 change0.10.20.4-0.5-0.60.6-0.60.6-0.50.7-0.20.5-0.2-0.3-0.30.1-0.4
Intermittent access intake escalation0.20.40.7-0.7-0.80.8-0.70.6-0.70.8-0.20.5-0.4-0.7-0.4-0.2-0.7
Intermittent access intake escalation 20.10.10.90.10.20.20.00.1-0.10.31.0-0.20.10.2-0.5-0.40.2
Intermitt. access day 1 inactive lever presses2.07.513.5-3.7-3.63.3-3.22.8-2.72.6-2.92.6-2.0-2.4-1.20.7-3.0
Intermitt. access day 15 inactive lever presses0.91.84.0-2.0-1.61.7-0.71.0-1.71.1-1.70.9-1.4-1.5-0.80.1-1.2
Intermitt. access escalation Index0.10.20.5-0.3-0.00.20.2-0.5-0.7-0.3-0.4-0.4-0.7-0.00.3-0.50.4
Intermittent access day 1 total infusions0.30.40.90.2-0.30.1-0.70.90.70.70.50.80.8-0.1-0.40.9-0.9
Intermittent access day 15 total infusions0.60.81.8-0.5-1.00.7-1.21.3-0.01.30.01.30.5-0.5-0.80.8-1.3
Intermittent access terminal intake (last 3 days)0.50.71.70.4-0.30.0-0.81.20.91.00.91.01.30.2-0.80.8-0.8
Intermittent access total infusions0.60.71.7-0.2-0.80.4-1.01.30.41.00.01.30.8-0.3-0.61.0-1.2
Intermittent access day 1 locomotion1.11.42.9-1.0-1.50.9-1.71.7-0.11.3-1.01.60.2-0.6-0.41.1-1.6
Intermittent access day 15 total locomotion0.30.51.4-0.4-0.80.5-1.01.20.10.9-0.60.80.30.4-0.30.9-0.4
Intermittent access total locomotion1.51.83.9-1.2-1.71.2-1.82.0-0.21.6-1.31.70.1-0.6-0.71.2-1.6
Intermittent access standard deviation0.40.91.6-1.0-1.11.1-1.21.2-0.61.3-0.21.2-0.1-0.5-1.10.4-1.0
Left kidney weight0.20.92.40.90.5-0.2-0.10.71.20.80.80.61.61.5-1.51.10.0
Right kidney weight0.10.71.90.90.6-0.30.10.51.10.61.10.11.31.4-1.20.50.0
Cocaine induced anxiety0.60.93.10.71.2-0.31.8-0.9-0.2-0.40.5-1.3-0.11.6-0.5-0.41.4
Post-drug Anxiety1.01.13.10.81.3-0.71.8-1.4-0.0-1.00.5-1.5-0.30.80.4-1.01.2
Baseline Anxiety0.60.62.7-0.4-0.3-0.2-0.3-0.6-0.4-0.8-0.7-0.3-0.9-1.61.6-0.7-0.6
Tail length2.28.424.14.33.0-4.02.1-0.94.9-1.71.9-0.44.73.50.22.20.0
Length with tail2.310.027.54.73.4-4.42.4-1.35.2-2.02.2-0.74.94.00.42.00.0
Length without tail0.61.93.81.91.6-2.01.3-1.41.6-1.61.4-1.11.21.41.3-0.30.0
Times rat made contact with spout0.20.31.1-0.4-0.80.3-1.00.6-0.00.4-0.30.70.1-0.70.30.30.0
Lifetime Intake0.30.41.1-0.1-0.60.2-0.90.90.40.70.21.00.7-0.3-0.20.8-0.9
Liver weight, left0.50.82.80.70.7-1.00.8-0.80.9-1.01.7-0.80.2-0.51.0-1.50.0
Liver weight, right0.20.31.4-0.4-0.30.5-0.00.6-0.00.8-0.50.70.2-0.1-1.20.60.0
Locomotor activity0.30.41.4-0.9-0.60.8-0.20.1-1.20.3-0.40.2-1.1-1.10.1-0.50.0
Locomotor testing distance0.30.51.4-0.00.3-0.30.5-0.8-0.5-0.80.5-0.7-0.8-0.91.2-1.10.0
Locomotor testing rearing0.30.61.40.40.8-0.41.0-1.0-0.4-0.80.7-1.0-0.8-0.40.9-1.20.0
Locomotion in novel chamber0.20.31.0-0.4-0.40.3-0.40.0-0.6-0.10.6-0.1-0.7-1.00.8-0.9-0.3
Locomotion in novel chamber post-restriction0.40.61.4-0.9-1.20.8-1.11.0-0.60.8-0.90.6-0.50.50.30.30.3
Fecal boli incidents, locomotor time 10.91.33.1-0.6-1.10.8-1.41.50.01.4-1.11.80.8-0.4-1.21.60.0
Change in fecal boli incidents, locomotor task1.11.03.40.00.8-0.10.8-1.4-0.8-1.11.1-1.6-1.40.00.7-1.80.0
Time >=10cm from walls, locomotor time 10.00.00.20.10.3-0.10.4-0.30.2-0.2-0.1-0.10.0-0.2-0.1-0.20.0
Bouts of movement, locomotor time 11.61.95.51.91.3-1.61.0-0.32.3-0.40.50.22.31.8-0.51.50.0
Total resting periods, locomotor time 11.41.64.41.81.3-1.61.1-0.42.1-0.60.3-0.02.11.5-0.31.30.0
Rest time, locomotor task time 11.31.73.71.91.7-1.41.6-0.61.8-0.41.4-0.61.81.4-0.70.60.0
Distance moved, locomotor task time 10.61.03.0-1.5-1.01.2-0.80.2-1.60.3-1.40.0-1.7-0.70.4-0.60.0
Vertical activity count, locomotor time 10.61.43.3-1.7-1.81.2-1.61.0-1.10.7-1.81.0-1.2-1.00.60.00.0
Time >=10cm from walls, locomotor time 20.20.41.7-0.6-0.10.7-0.1-0.3-0.9-0.0-0.2-0.6-1.3-0.00.2-1.00.0
Bouts of movement, locomotor time 21.93.16.82.62.2-2.22.0-1.22.3-1.20.8-0.62.32.6-0.31.20.0
Total resting periods, locomotor time 21.93.37.22.62.2-2.22.0-1.12.5-1.10.9-0.42.52.7-0.51.40.0
Rest time, locomotor task time 22.12.65.42.32.3-1.82.0-1.12.0-0.92.0-1.11.81.9-0.70.40.0
Distance moved, locomotor task time 21.31.52.8-1.7-1.61.7-1.51.3-1.31.4-1.61.1-1.0-0.7-0.50.30.0
Vertical activity count, locomotor time 20.91.22.8-1.4-1.71.2-1.61.3-0.81.1-1.31.2-0.6-0.7-0.00.40.0
Light reinforcement 10.30.73.3-0.9-0.90.1-0.6-0.1-0.9-0.5-1.10.1-1.1-1.11.8-0.60.0
Light reinforcement 20.40.62.7-0.8-1.00.6-1.10.7-0.50.5-1.60.7-0.4-0.10.20.60.0
Bone: marrow area0.51.02.01.41.4-1.41.4-1.01.2-1.00.7-0.61.01.10.3-0.10.0
Bone: maximum diameter0.40.83.20.60.7-0.20.60.20.70.6-0.60.61.21.3-1.81.40.0
Bone: maximum force0.91.72.9-1.4-1.61.5-1.61.7-0.91.7-1.31.6-0.2-0.8-1.21.20.0
Bone: maximum moment0.71.12.0-1.1-1.31.2-1.31.4-0.71.4-1.11.4-0.1-0.8-1.01.10.0
Mean time between licks in bursts0.40.92.91.40.9-1.40.8-0.31.7-0.60.4-0.21.50.40.40.70.0
Mean num. licks in bursts0.00.10.30.30.5-0.20.4-0.40.1-0.30.0-0.20.10.3-0.3-0.00.0
Cd content in liver0.70.83.5-1.0-0.41.00.2-0.3-1.9-0.0-0.3-0.5-1.7-0.90.2-0.90.0
Co content in liver1.31.64.8-1.6-1.51.5-1.01.1-1.51.2-2.21.2-1.0-0.8-0.50.80.0
Cu content in liver0.60.72.10.7-0.2-1.1-0.60.31.3-0.3-0.21.01.50.61.01.20.0
Fe content in liver1.01.23.91.60.9-1.70.2-0.42.0-0.81.2-0.21.70.60.90.30.0
K content in liver0.70.61.81.00.5-1.30.4-0.41.3-0.9-0.00.11.10.51.10.50.0
Mg content in liver1.11.12.61.51.2-1.51.0-0.81.6-1.00.4-0.41.41.30.40.50.0
Mn content in liver2.12.34.92.22.1-1.91.8-1.22.1-1.21.1-0.91.71.9-0.00.30.0
Na content in liver0.91.06.50.2-0.0-1.00.4-0.90.0-1.50.3-0.6-0.4-1.32.5-0.90.0
Rb content in liver0.20.30.70.80.6-0.70.3-0.20.6-0.20.6-0.20.60.70.30.20.0
Se content in liver1.41.74.12.01.6-1.90.9-0.92.0-1.11.1-0.41.81.30.40.60.0
Sr content in liver0.60.61.5-0.7-0.70.8-0.60.8-0.30.8-1.21.00.0-0.4-1.00.90.0
Zn content in liver0.50.52.30.3-0.2-0.2-0.30.60.70.4-0.81.01.10.8-0.61.50.0
Bone: minimum diameter0.00.10.3-0.00.00.00.40.10.00.1-0.50.40.20.2-0.60.50.0
Time in familiar zone, hab. session 10.50.51.80.6-0.0-0.6-0.50.31.10.1-0.30.51.11.30.31.00.0
Time in novel zone, hab. session 10.50.52.4-0.9-0.50.9-0.10.3-0.90.5-0.50.3-0.8-1.6-0.9-0.20.0
Total zone transitions, hab. session 10.91.32.8-1.7-1.41.6-1.40.8-1.60.9-0.60.4-1.6-1.20.1-0.70.0
Total locomotion distance, hab. session 10.30.41.7-0.5-1.00.3-1.30.80.20.4-0.10.80.2-0.60.40.20.0
Locomotion velocity, hab. session 10.10.20.9-0.2-0.60.1-0.90.50.20.20.30.40.2-0.50.5-0.10.0
Time in familiar zone, hab. session 20.30.32.0-0.5-0.70.3-0.60.3-0.40.2-1.40.6-0.30.30.50.60.0
Time in novel zone, hab. session 20.20.21.10.30.4-0.00.4-0.00.30.11.0-0.30.4-0.4-1.0-0.30.0
Total zone transitions, hab. session 20.81.02.2-1.4-1.51.0-1.31.0-0.90.7-0.50.5-1.1-1.40.6-0.60.0
Total locomotion distance, hab. session 20.60.71.90.0-1.0-0.4-1.41.21.30.40.11.11.1-0.60.80.60.0
Locomotion velocity, hab. session 20.50.62.10.3-0.7-0.6-1.10.91.50.20.40.81.2-0.40.90.50.0
Novel to familiar place preference ratio0.40.41.8-0.8-0.90.5-0.70.6-0.40.4-0.60.8-0.2-1.4-0.00.20.0
Novelty place preference0.50.61.9-0.9-1.10.6-0.80.9-0.30.6-0.81.0-0.0-1.4-0.30.50.0
Time in novel zone, NPP test0.60.61.8-0.8-1.10.6-0.90.9-0.20.7-0.81.10.0-1.3-0.30.50.0
Total zone transitions, NPP test0.40.52.8-0.5-0.90.1-1.20.2-0.3-0.20.50.1-0.7-0.81.7-0.90.0
Total locomotion distance, NPP test0.40.51.50.4-0.6-0.8-1.00.51.2-0.20.50.71.00.01.20.30.0
Locomotion velocity, NPP test0.40.52.40.3-0.6-0.8-1.10.41.1-0.30.60.50.8-0.21.5-0.00.0
Intraocular pressure0.30.41.6-0.6-0.20.9-0.00.1-1.30.50.4-0.1-0.9-0.7-0.7-0.50.0
Delta distance traveled before/after self-admin1.61.72.7-1.6-1.61.6-1.51.3-1.31.3-0.61.1-0.9-1.7-0.8-0.1-1.6
Delta ambulatory time before/after self-admin1.21.43.5-1.5-1.41.4-1.21.0-1.31.1-0.51.0-1.0-1.6-0.5-0.3-1.9
Parametrial fat weight0.20.42.00.40.0-1.00.1-0.40.7-0.90.10.00.4-0.91.4-0.50.0
Pavlov. Cond. lever latency1.92.34.6-2.1-2.12.1-1.81.5-1.81.5-1.41.2-1.3-1.8-0.70.00.0
Pavlov. Cond. magazine entry latency5.16.613.42.42.6-3.13.0-3.31.3-3.72.6-3.00.10.63.5-2.50.0
Pavlov. Cond. change in total contacts4.14.49.12.32.1-3.02.2-2.41.8-2.92.0-2.00.80.83.0-1.40.0
Pavlov. Cond. index score3.44.37.82.32.4-2.62.5-2.61.3-2.82.2-2.40.41.12.4-1.60.0
Pavlov. Cond. latency score3.44.37.22.42.5-2.72.6-2.51.5-2.62.2-2.20.71.32.0-1.30.0
Pavlov. Cond. lever contacts1.82.24.02.02.0-2.01.9-1.71.4-1.71.2-1.31.01.51.0-0.30.0
Pavlov. Cond. magazine entry number4.05.014.3-1.7-1.92.6-2.22.8-0.93.2-2.22.60.40.0-3.82.60.0
Pavlov. Cond. intertrial magazine entries2.93.510.1-1.2-1.42.0-2.12.5-0.42.8-1.52.30.6-0.3-3.22.20.0
Pavlov. Cond. lever-magazine prob. diff.3.34.07.72.12.2-2.52.4-2.61.2-2.82.1-2.30.30.92.6-1.60.0
Pavlov. Cond. response bias3.84.79.42.12.2-2.72.5-2.81.2-3.12.1-2.60.10.73.0-2.10.0
Pavlov. Cond. lever latency0.70.92.40.91.1-1.11.5-1.40.2-1.2-0.2-0.80.11.60.9-0.10.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.4-0.10.4-0.10.2-0.10.20.0-0.1-0.3-0.3-0.5-0.40.0
Pavlov. Cond. change in total contacts0.20.21.40.1-0.1-0.1-0.30.30.40.01.2-0.10.3-1.20.1-0.50.0
Pavlov. Cond. index score0.10.20.6-0.1-0.20.2-0.50.60.30.40.80.10.2-0.8-0.6-0.20.0
Pavlov. Cond. latency score0.10.11.0-0.0-0.00.1-0.30.30.30.21.0-0.10.2-0.6-0.4-0.40.0
Pavlov. Cond. lever contacts1.01.33.3-1.3-1.41.3-1.81.6-0.41.4-0.11.1-0.3-1.8-0.90.10.0
Pavlov. Cond. magazine entry number0.10.20.80.30.1-0.30.0-0.00.20.0-0.80.50.40.70.10.90.0
Pavlov. Cond. intertrial magazine entries0.71.12.9-0.5-1.00.7-1.41.30.21.3-1.31.70.7-0.2-0.91.60.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.70.0-0.10.1-0.30.40.40.30.9-0.10.2-0.7-0.4-0.30.0
Pavlov. Cond. response bias0.91.33.9-1.4-1.51.4-1.61.4-0.71.2-0.30.9-0.6-2.0-0.6-0.20.0
Time in closed arm before self-admin0.60.82.0-1.2-0.71.3-0.70.2-1.40.50.2-0.3-1.40.1-0.4-1.21.3
Time in closed arm after self-admin0.40.41.90.60.5-0.50.2-0.30.7-0.31.4-0.50.40.50.1-0.61.1
Time in open arm before self-admin0.30.30.90.70.6-0.40.40.00.60.10.60.40.90.1-0.90.5-0.8
Time in open arm after self-admin0.20.20.8-0.6-0.50.5-0.20.3-0.70.3-0.00.3-0.5-0.5-0.0-0.3-0.9
Bone: periosteal estimation0.20.51.30.90.7-0.60.60.01.00.10.00.21.21.1-0.70.90.0
Bone: periosteal perimeter0.20.41.10.60.5-0.40.60.10.70.2-0.50.30.90.7-0.91.00.0
Bone: post-yield work0.10.10.7-0.1-0.20.3-0.10.40.10.4-0.30.50.30.1-0.80.60.0
Progressive ratio test 1 active lever presses1.41.84.2-0.7-1.50.8-1.71.90.21.6-1.42.00.80.2-0.82.0-1.1
Progressive ratio test 1 breakpoint1.31.53.6-0.7-1.40.8-1.61.70.21.5-1.21.90.70.2-0.71.8-1.0
Progressive ratio test 1 inactive lever presses3.55.111.4-3.0-3.42.4-3.02.4-1.92.0-2.22.4-1.4-2.30.10.6-2.2
Progressive ratio test 2 active lever presses0.30.41.20.3-0.3-0.2-0.20.60.60.4-0.10.81.00.9-0.21.10.2
Progressive ratio test 2 breakpoint0.30.31.10.1-0.3-0.1-0.30.60.40.5-0.20.80.90.7-0.21.00.1
Progressive ratio test 2 inactive lever presses0.40.61.2-1.0-1.11.0-0.80.8-0.80.8-0.60.8-0.5-0.7-0.30.2-0.9
Incentive Sensitization - Responses0.20.20.60.50.4-0.50.7-0.30.4-0.30.5-0.30.50.80.2-0.10.8
Incentive Sensitization - Breakpoint0.20.20.70.50.4-0.50.7-0.30.3-0.30.5-0.30.50.80.1-0.10.8
Sum of active levers in priming session hrs 5-61.41.33.0-0.20.6-0.21.0-1.5-1.3-1.30.0-1.6-1.7-1.11.6-1.6-0.0
Progressive ratio1.32.04.4-1.2-1.71.2-1.71.5-0.51.4-1.92.10.2-0.8-0.81.6-1.9
Food seeking constrained by brief footshock0.40.51.10.90.5-1.00.4-0.31.0-0.60.30.00.91.00.70.51.1
Seeking ratio, punishment vs. effort1.62.34.91.61.6-1.81.7-1.61.0-1.81.6-1.70.40.91.6-1.12.2
Retroperitoneal fat weight0.10.62.20.40.2-0.90.3-0.80.5-1.20.9-0.60.1-0.81.5-1.10.0
Reaction time number correct0.10.20.9-0.4-0.20.2-0.0-0.3-0.8-0.2-0.0-0.2-0.7-1.00.6-0.50.0
Reaction time mean minus median1.12.88.11.72.2-1.42.3-2.00.5-1.72.8-2.20.00.90.5-1.70.0
Reaction time mean minus median AUC0.81.95.11.72.0-1.31.8-1.50.8-1.12.2-1.60.61.5-0.1-0.80.0
Reaction time num false alarms1.01.43.4-1.7-1.81.2-1.71.1-1.30.8-0.80.8-1.2-1.60.8-0.30.0
Reaction time num false alarms AUC0.91.53.7-1.7-1.91.2-1.71.2-1.20.8-0.91.0-1.1-1.50.9-0.30.0
Reaction time trials correct on left0.10.20.9-0.4-0.20.2-0.0-0.3-0.8-0.2-0.0-0.2-0.7-1.00.6-0.50.0
Reaction time trials on left0.10.20.9-0.4-0.20.2-0.0-0.3-0.8-0.20.0-0.2-0.7-1.00.6-0.50.0
Reaction time mean0.40.62.3-0.60.10.80.4-0.4-1.50.10.5-0.7-1.50.0-0.2-1.10.0
Reaction time mean AUC0.20.31.3-0.40.20.70.4-0.3-1.10.30.3-0.5-1.00.4-0.6-0.60.0
Median of all reaction times0.60.93.9-1.3-0.61.4-0.30.2-2.00.7-0.4-0.1-1.8-0.3-0.4-0.80.0
Reaction time omissions0.10.21.20.30.10.1-0.30.40.40.51.10.10.60.2-0.70.00.0
Reaction time false alarm rate0.40.61.7-1.0-1.30.7-1.31.0-0.50.7-0.60.8-0.5-0.70.5-0.00.0
Reaction time premature initiation rate3.54.89.12.32.7-2.62.6-3.01.4-3.02.6-2.50.40.22.1-2.00.0
Reaction time premature initiations2.13.87.31.82.2-2.22.2-2.70.8-2.72.3-2.3-0.1-0.32.2-2.00.0
Std. dev. reaction times0.51.03.20.71.3-0.41.4-1.2-0.4-0.81.8-1.4-0.50.60.1-1.30.0
Reaction time trials completed0.10.20.9-0.4-0.20.2-0.0-0.3-0.8-0.20.0-0.2-0.7-1.00.6-0.50.0
Reaction time trials AUC0.10.21.1-0.5-0.50.3-0.2-0.0-0.80.0-0.10.0-0.7-1.10.5-0.40.0
Run reversals in cocaine runway, females0.80.81.91.20.8-1.30.8-0.41.4-0.60.4-0.01.31.10.50.81.0
Run reversals in cocaine runway, males0.80.82.60.00.4-0.40.9-0.9-0.5-0.90.7-1.1-0.9-1.61.1-1.2-0.6
Latency to leave start box in cocaine runway0.10.10.2-0.3-0.40.2-0.40.2-0.20.2-0.0-0.2-0.40.30.4-0.40.3
Latency to leave start box in cocaine runway, F0.10.10.4-0.2-0.30.1-0.3-0.0-0.1-0.0-0.1-0.3-0.4-0.20.6-0.50.1
Latency to leave start box in cocaine runway, M0.10.10.3-0.5-0.50.4-0.40.6-0.30.3-0.00.1-0.40.50.0-0.20.3
Std. dev. time between licks in bursts0.70.91.91.41.3-1.41.2-0.71.4-0.81.2-0.81.10.00.2-0.10.0
Total sessions with >9 infusions1.01.22.8-0.8-1.40.6-1.71.50.01.1-1.01.70.4-0.2-0.11.3-1.1
Short access day 1 total inactive lever presses1.92.54.8-2.2-2.01.9-1.71.2-1.81.2-2.01.2-1.5-1.7-0.30.1-1.6
Short access day 10 total inactive lever presses1.12.66.3-2.5-2.01.9-1.10.7-2.40.8-1.60.9-2.1-1.9-0.1-0.8-1.5
Short access day 1 total infusions0.20.30.7-0.6-0.80.5-0.80.6-0.30.6-0.50.7-0.1-0.60.00.3-0.7
Short access day 10 total infusions0.50.61.8-0.5-1.10.2-1.11.10.30.6-0.51.40.6-0.80.11.0-0.9
Short access total infusions0.10.20.60.4-0.1-0.3-0.30.40.60.20.40.50.80.30.10.6-0.1
Short access day 1 locomotion0.40.52.0-0.8-1.10.3-0.70.7-0.20.3-1.40.6-0.3-0.40.80.5-0.3
Short access day 10 total locomotion1.01.84.2-1.0-1.80.7-1.72.00.21.2-1.72.10.70.5-0.41.9-0.8
Short access total locomotion2.12.55.7-1.3-2.11.1-2.12.4-0.01.7-2.02.30.50.1-0.62.0-1.3
One hour access (0.3 mA shock)0.20.20.6-0.3-0.70.4-0.80.7-0.10.50.30.5-0.1-0.20.30.2-0.6
Compulsive drug intake0.20.30.70.2-0.3-0.4-0.50.40.90.0-0.10.60.70.60.50.60.5
One hour access (shock baseline)0.30.41.3-0.4-0.60.6-0.70.9-0.10.80.10.60.2-0.6-0.60.5-1.1
Social response proportion0.10.10.2-0.3-0.10.3-0.20.1-0.10.3-0.50.0-0.40.4-0.1-0.30.0
Social responses0.10.10.9-0.0-0.1-0.2-0.0-0.2-0.0-0.2-0.0-0.2-0.30.10.9-0.60.0
Social time1.21.63.0-1.5-1.41.7-1.11.4-1.21.7-1.71.3-0.6-0.4-1.40.80.0
Soleus weight0.82.46.01.11.9-1.22.5-2.3-0.4-1.91.0-2.4-0.90.91.3-1.60.0
Bone: stiffness0.40.62.1-1.0-1.10.8-0.90.7-0.70.6-0.90.8-0.5-1.50.10.30.0
Tibialis anterior weight0.82.95.9-1.4-1.81.8-2.12.3-0.52.4-2.02.00.20.2-2.02.00.0
Time to tail flick, vehicle, before self-admin1.81.93.71.81.3-1.91.3-0.81.9-1.21.3-0.91.61.30.80.31.9
Time to tail flick, vehicle, after self-admin0.40.51.00.90.9-0.50.6-0.30.8-0.21.0-0.60.80.9-0.80.10.8
Time to tail flick, test, before self-admin2.62.76.11.91.1-2.31.2-0.82.3-1.50.8-0.12.02.41.30.92.5
Time to tail flick, test, after self-admin4.74.99.83.12.6-3.02.2-1.52.9-1.81.9-1.12.72.60.50.72.1
Delta time to tail flick, vehicle, before/after SA0.90.92.1-1.0-0.61.2-0.70.4-1.30.8-0.70.3-1.1-1.4-0.8-0.3-1.4
Delta time to tail flick, test, before/after SA0.30.30.90.70.9-0.40.7-0.60.3-0.30.6-0.80.20.1-0.3-0.3-0.2
Tibia length0.41.25.01.00.0-1.1-0.30.71.80.2-0.11.42.20.6-0.12.00.0
Ambulatory time before self-admin2.23.36.62.22.4-2.02.1-2.01.3-1.71.9-2.10.81.50.9-0.92.6
Ambulatory time after self-admin1.11.33.81.51.7-1.01.4-1.10.7-0.82.0-1.30.60.7-0.2-0.61.1
Bone: tissue strength0.90.95.2-1.2-1.10.9-0.80.5-1.00.4-0.40.3-1.1-2.30.4-0.60.0
Total heroin consumption0.91.12.60.51.2-0.51.4-1.6-0.6-1.20.4-1.4-1.00.40.8-1.01.2
Bone: trabecular number0.20.30.70.60.7-0.60.6-0.70.2-0.60.8-0.60.1-0.30.4-0.50.0
Bone: trabecular spacing0.20.31.1-0.5-0.30.4-0.1-0.0-0.60.1-1.0-0.1-0.70.90.3-0.10.0
Bone: trabecular thickness0.30.41.50.50.3-0.80.2-0.30.7-0.61.0-0.20.5-1.20.8-0.50.0
Bone: trabecular tissue density0.30.52.5-0.6-0.5-0.0-0.3-0.3-0.5-0.6-0.2-0.4-0.9-1.01.6-1.10.0
Water consumed over 24 hours0.10.20.4-0.5-0.30.6-0.30.1-0.60.20.0-0.1-0.7-0.6-0.1-0.50.0
Number of responses in last shaping day0.91.03.0-0.3-0.50.6-0.51.10.31.1-1.21.30.81.0-1.51.7-0.4