Hub : Genes

Nup50

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Nup50 0.09 0.06 4.9e-04 0.08 0.07 0.09 0.09 3.3e-04 8.6e-04 2.0e-04 2.0e-04
2 Liver mRNA stability Nup50 0.02 0.02 3.7e-03 0.01 -0 0.01 0.01 8.5e-03 5.1e-01 4.7e-02 1.9e-02
3 Liver gene expression Nup50 0.03 0.02 1.8e-03 0.02 0.01 0 0.01 2.3e-03 4.4e-02 1.5e-01 5.6e-02
4 Adipose gene expression Nup50 0.15 0.09 3.1e-11 0.06 0.03 0.07 0.02 1.9e-07 2.3e-04 8.3e-08 3.2e-03
5 BLA gene expression Nup50 0.09 0.06 2.8e-05 0.07 0.06 0.07 0.06 2.2e-04 3.4e-04 1.2e-04 5.0e-04
6 Brain gene expression Nup50 0.17 0.07 0.0e+00 0.22 0.14 0.23 0.23 9.2e-21 2.2e-13 2.6e-21 2.1e-21
7 Eye gene expression Nup50 0.35 0.24 1.2e-03 0.15 0.12 0.15 0.17 2.4e-03 6.0e-03 2.6e-03 1.5e-03
8 PL gene expression Nup50 0.21 0.09 0.0e+00 0.15 0.2 0.2 0.19 1.5e-16 3.4e-21 7.5e-22 2.2e-20
9 NAcc gene expression Nup50 0.16 0.11 1.4e-10 0.05 0.06 0.06 0.06 1.2e-08 2.0e-09 9.3e-10 1.3e-09
10 NAcc intron excision ratio chr7_117928190_117931523 0.07 0.04 4.3e-08 0.03 0.04 0.04 0.05 4.9e-06 1.7e-07 2.9e-07 1.2e-07
11 IL gene expression Nup50 0.39 0.14 3.4e-08 0.13 0.27 0.19 0.22 4.3e-04 3.5e-07 2.3e-05 5.5e-06
12 Brain mRNA stability Nup50 0.24 0.1 0.0e+00 0.25 0.26 0.26 0.25 3.5e-23 1.2e-23 1.2e-24 3.2e-23
13 Liver intron excision ratio chr7_117928190_117931523 0.04 0.04 9.1e-03 0.02 0.01 0.01 0.02 2.4e-03 1.6e-02 7.5e-03 5.4e-03
14 Liver intron excision ratio chr7_117931601_117933612 0.04 0.04 7.5e-03 0.02 0.01 0.01 0.01 3.5e-03 2.8e-02 1.5e-02 2.3e-02
15 OFC gene expression Nup50 0.34 0.16 1.6e-04 0.11 0.11 0.16 0.17 1.2e-03 1.5e-03 1.5e-04 8.1e-05
16 RMTg mRNA stability Nup50 0.34 0.14 1.7e-06 0.16 0.15 0.16 0.21 5.5e-05 1.0e-04 5.4e-05 2.5e-06
17 NAcc intron excision ratio chr7_117931601_117933612 0.07 0.04 1.8e-08 0.05 0.05 0.05 0.05 9.8e-08 2.7e-08 1.2e-07 5.5e-08
18 NAcc mRNA stability Nup50 0.05 0.03 6.4e-06 0.04 0.03 0.03 0.04 1.8e-07 1.1e-05 7.3e-06 9.1e-07
19 PL mRNA stability Nup50 0.09 0.05 6.3e-07 0.05 0.05 0.05 0.05 2.9e-06 2.2e-06 2.6e-06 2.0e-06
20 pVTA mRNA stability Nup50 0.13 0.11 3.2e-04 0.03 0.03 0.04 0.04 1.3e-03 9.6e-04 2.2e-04 6.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.61.01.9-1.41.2-1.3-1.0-1.1-1.1-1.4-1.1-1.3-1.1-0.90.8-1.01.0-0.20.20.90.80.60.4
Area under the delay curve1.21.44.4-0.91.3-1.4-1.0-1.3-0.9-1.9-0.7-0.6-1.8-0.30.3-2.12.10.20.01.9-0.4-0.20.4
BMI with tail1.86.312.03.4-3.33.32.52.72.91.82.83.51.12.7-3.00.7-0.72.9-3.0-0.6-2.3-2.4-1.0
BMI without tail0.20.61.21.0-0.80.90.80.70.90.20.91.10.60.9-0.80.2-0.20.9-0.9-0.5-0.8-0.5-0.2
Body weight1.25.111.12.9-3.03.02.32.52.72.12.53.31.62.3-2.31.6-1.62.0-2.2-1.4-1.6-1.7-0.6
Weight adjusted by age0.50.71.40.6-1.01.11.00.81.00.80.81.01.20.6-0.31.2-1.20.5-0.5-1.1-0.2-0.0-0.8
Bone surface0.20.30.7-0.50.7-0.7-0.5-0.6-0.6-0.8-0.4-0.6-0.8-0.40.1-0.80.80.2-0.10.70.10.2-0.2
Bone volume0.20.41.0-0.80.7-0.8-0.6-0.7-0.8-0.8-0.7-1.0-0.6-0.60.5-0.60.6-0.10.10.50.60.40.2
Breakpoint value in progressive ratio session0.20.30.70.8-0.60.50.70.80.60.10.50.30.30.6-0.70.2-0.20.5-0.7-0.2-0.5-0.7-0.2
Number of licking bursts0.71.22.4-1.41.2-1.2-1.0-1.0-1.2-0.9-1.4-1.6-0.1-1.41.40.1-0.1-1.31.2-0.31.31.30.2
Context. condit. distance diff. score2.12.65.32.3-1.91.92.12.11.82.21.90.91.71.6-1.41.0-1.00.6-0.7-1.1-1.3-1.2-1.7
Locomotion velocity, session 10.60.72.01.0-0.70.71.41.21.30.80.90.30.81.0-0.70.7-0.70.5-0.6-0.7-0.2-0.70.0
Locomotion distance, session 10.20.21.0-0.50.3-0.3-0.3-0.4-0.60.3-0.5-1.0-0.0-0.50.5-0.30.3-0.50.70.10.60.40.7
Locomotion velocity, session 22.32.75.31.9-1.91.91.91.82.01.81.52.22.31.4-1.02.1-2.10.6-1.0-2.0-0.6-0.40.3
Locomotion distance, session 20.20.20.90.1-0.40.30.00.10.1-0.10.20.3-0.70.4-0.6-0.40.40.9-0.70.7-0.5-0.70.7
Locomotion velocity, session 32.02.37.41.4-1.81.91.21.41.12.70.80.42.70.4-0.02.4-2.4-0.80.5-2.20.50.40.1
Locomotion distance, session 31.21.33.1-0.5-0.10.1-0.8-0.5-0.61.0-0.9-0.61.4-1.11.31.5-1.5-1.81.6-1.51.61.60.9
Stereotopy head waving bouts, day 31.92.24.31.9-1.31.42.11.91.91.21.91.90.81.7-1.70.5-0.51.2-1.4-0.4-1.6-1.4-1.5
Stereotopy head waving duration, day 32.83.47.12.3-1.92.02.72.52.31.92.11.81.62.0-1.81.1-1.11.5-1.9-1.1-1.5-1.5-1.2
Locomotion velocity, session 70.91.03.90.8-1.21.20.60.80.62.00.50.31.80.30.11.5-1.5-0.50.2-1.50.20.3-0.1
Locomotion distance, session 70.10.10.3-0.1-0.20.1-0.3-0.2-0.20.6-0.1-0.30.4-0.20.30.4-0.4-0.50.5-0.20.10.30.4
Stereotopy head waving bouts, day 72.12.46.11.7-1.61.72.01.91.62.11.20.72.51.0-0.62.2-2.20.0-0.4-2.30.2-0.0-0.3
Stereotopy head waving duration, day 71.11.33.91.2-0.91.01.51.41.11.50.80.72.00.6-0.21.8-1.8-0.1-0.2-1.90.20.1-0.1
Locomotion velocity, session 86.27.413.73.7-3.43.43.53.63.43.13.01.82.42.8-2.62.3-2.32.1-2.4-2.1-1.8-2.1-0.5
Locomotion distance, session 81.42.04.31.9-2.01.91.71.81.52.11.60.71.71.2-1.11.3-1.30.5-0.4-1.3-0.9-0.8-0.7
Degree of sensitization distance1.92.05.01.2-0.80.71.21.21.30.21.61.3-0.81.7-1.7-1.01.01.9-1.81.2-2.2-2.0-1.2
Degree of sensitization stereotypy1.21.33.91.2-1.21.31.31.31.01.50.70.42.00.5-0.21.7-1.7-0.1-0.2-2.00.40.20.1
Conditioned locomotion0.20.20.8-0.30.1-0.2-0.8-0.5-0.70.4-0.4-0.10.2-0.50.5-0.20.2-0.70.70.00.20.4-0.9
Cocaine response after cond. corrected0.60.71.6-1.30.8-0.8-0.2-0.6-1.0-0.6-1.1-1.10.2-1.01.20.2-0.2-0.90.8-0.51.21.10.5
Cocaine response after cond. not corrected1.31.63.6-1.51.0-1.0-0.5-0.8-1.2-0.4-1.5-1.40.7-1.51.70.9-0.9-1.51.3-1.11.91.81.0
Cocaine response before conditioning0.40.41.1-0.50.5-0.6-1.0-0.8-0.50.1-0.7-0.40.2-0.80.80.4-0.4-0.90.8-0.30.90.90.5
Saline control response0.60.71.9-0.60.8-0.8-0.3-0.5-0.8-0.1-0.8-1.10.7-1.01.10.6-0.6-1.41.3-0.71.11.10.3
Bone: connectivity density0.20.40.9-0.81.0-1.0-0.6-0.6-0.6-0.9-0.6-0.7-0.6-0.60.4-0.60.6-0.00.10.50.40.30.1
Bone: cortical apparent density0.60.82.0-1.01.3-1.3-0.9-0.9-0.8-0.9-0.5-0.3-1.2-0.50.4-1.41.4-0.40.51.4-0.2-0.1-1.0
Bone: cortical area0.30.40.90.7-1.01.00.40.60.50.80.40.40.90.4-0.40.9-0.90.3-0.4-0.90.1-0.10.0
Bone: cortical porosity0.00.00.2-0.10.0-0.1-0.2-0.2-0.00.1-0.20.30.2-0.00.1-0.10.1-0.0-0.2-0.20.20.20.5
Bone: cortical porosity0.10.10.30.3-0.30.30.30.20.40.30.30.50.40.4-0.3-0.00.00.3-0.5-0.3-0.1-0.20.2
Bone: cortical thickness0.20.30.9-0.60.5-0.5-0.5-0.4-0.4-0.5-0.2-0.5-0.9-0.1-0.0-0.90.90.3-0.10.90.0-0.3-0.6
Bone: cortical thickness0.50.61.80.6-0.40.40.30.50.40.30.70.8-0.60.8-1.0-0.80.81.1-1.01.0-1.1-1.3-0.7
Bone: cortical tissue density0.50.71.7-0.81.1-1.1-0.7-0.7-0.7-0.8-0.3-0.1-1.1-0.30.3-1.21.2-0.30.41.3-0.4-0.2-1.1
Condit. Reinf. active minus inactive responses0.80.92.1-1.21.2-1.2-1.0-1.1-1.0-1.2-0.7-0.5-1.5-0.50.4-1.41.4-0.20.31.30.10.10.0
Condit. Reinf. active-inactive response ratio0.80.92.1-1.11.2-1.3-0.8-1.0-0.9-1.2-0.6-0.7-1.4-0.40.4-1.51.5-0.30.31.40.00.1-0.5
Condit. Reinf. active responses0.91.11.8-1.31.3-1.4-1.3-1.3-1.3-1.3-1.0-0.6-1.2-0.90.8-1.01.0-0.81.00.90.40.60.3
Condit. Reinf. inactive responses0.20.31.2-0.40.4-0.4-0.7-0.6-0.7-0.3-0.5-0.2-0.0-0.70.60.2-0.2-0.91.1-0.10.40.50.5
Incentive salience index mean0.70.81.7-1.31.0-1.0-1.2-1.2-1.2-0.7-1.0-0.9-1.0-0.90.8-0.80.8-0.60.70.80.60.60.5
Condit. Reinf. lever presses0.40.51.1-0.90.2-0.2-0.8-0.7-0.80.3-0.8-0.90.1-0.80.90.3-0.3-0.80.9-0.20.90.81.1
Condit. Reinf. active minus inactive responses0.50.72.21.1-1.11.00.10.60.80.50.60.7-0.50.7-1.2-0.20.21.5-1.40.4-0.5-1.10.7
Condit. Reinf. active-inactive response ratio0.20.21.80.3-0.50.40.00.20.00.1-0.2-0.4-0.40.0-0.4-0.00.00.9-0.80.20.3-0.51.3
Condit. Reinf. active responses1.72.34.72.2-2.01.90.91.41.91.31.71.80.11.7-2.10.3-0.32.0-2.00.1-1.4-1.7-0.0
Condit. Reinf. inactive responses2.02.65.62.0-1.91.91.21.62.01.62.12.40.51.9-2.00.3-0.31.7-1.6-0.1-1.8-1.6-1.2
Condit. Reinf. lever presses1.01.42.71.6-1.71.61.01.31.40.91.21.60.61.2-1.40.9-0.91.3-1.3-0.6-1.0-0.90.1
Condit. Reinf. lever reinforcers received1.11.63.21.8-1.71.60.61.11.51.01.31.5-0.11.4-1.80.1-0.11.8-1.70.2-1.2-1.50.0
Conditioned reinforcement - actives0.10.11.1-0.10.2-0.2-0.3-0.1-0.0-0.10.1-0.3-0.00.0-0.0-0.50.5-0.10.30.4-0.2-0.1-1.0
Conditioned reinforcement - inactives0.20.31.31.2-0.50.50.70.80.30.50.4-0.70.10.4-0.70.1-0.10.6-0.40.2-0.3-0.8-0.2
Conditioned locomotion0.40.62.50.5-0.40.41.10.90.40.80.3-0.71.60.10.11.3-1.3-0.10.1-1.30.40.20.3
Patch foraging indifference point 0 sec0.30.51.6-1.11.1-1.1-0.4-0.5-0.5-1.2-0.9-0.6-0.7-0.70.60.0-0.0-0.20.1-0.00.90.50.6
Patch foraging indifference point AUC0.10.20.8-0.20.4-0.4-0.3-0.1-0.2-0.20.00.3-0.80.0-0.3-0.90.90.1-0.00.8-0.2-0.4-0.6
Delay disc. indifference point, 0s delay0.10.10.30.40.0-0.10.50.20.4-0.40.40.60.10.5-0.3-0.10.10.1-0.30.1-0.3-0.4-0.1
Delay disc. indifference point, 16s delay1.82.05.3-1.82.0-2.1-1.0-1.6-1.0-2.3-0.9-0.4-1.9-0.60.8-2.12.1-0.30.51.7-0.20.30.1
Delay disc. indifference point, 2s delay0.50.62.0-0.20.7-0.7-0.7-0.8-0.7-1.1-0.5-0.7-1.1-0.2-0.0-1.41.40.2-0.21.4-0.1-0.4-0.1
Delay disc. indifference point, 24s delay0.20.20.80.10.2-0.1-0.4-0.30.0-0.8-0.0-0.0-0.90.3-0.3-0.80.80.6-0.60.7-0.4-0.40.2
Delay disc. indifference point, 4s delay1.41.45.0-0.41.1-1.1-0.0-0.6-0.3-2.0-0.2-0.5-1.80.3-0.3-2.22.20.9-0.72.2-0.8-0.9-0.6
Delay disc. indifference point, 8s delay0.91.13.0-0.60.9-1.0-1.3-1.3-0.7-1.5-0.5-0.1-1.7-0.30.0-1.71.70.20.11.7-0.7-0.20.8
Indifference point function ln k0.61.14.00.8-1.21.20.70.80.71.30.50.42.00.10.22.0-2.0-0.40.3-1.80.10.40.2
Indifference point function log k0.61.14.00.8-1.21.20.70.80.71.30.50.42.00.10.22.0-2.0-0.40.3-1.80.10.40.2
Patch foraging total patch changes 0 sec0.40.71.8-1.31.3-1.2-0.6-0.6-0.8-1.3-1.1-0.8-0.6-1.00.90.1-0.1-0.50.4-0.11.20.80.6
Patch foraging total patch changes 12 sec0.20.20.50.2-0.10.10.40.40.40.00.40.5-0.50.6-0.6-0.60.60.7-0.70.5-0.6-0.6-0.5
Patch foraging total patch changes 18 sec0.71.12.6-1.31.5-1.4-0.8-0.9-1.4-0.9-1.3-1.6-1.0-1.10.8-0.90.9-0.40.50.70.90.60.3
Patch foraging total patch changes 24 sec0.30.51.6-0.40.4-0.2-0.10.0-0.30.0-0.5-0.50.9-0.60.71.0-1.0-0.90.7-1.31.10.90.3
Patch foraging total patch changes 6 sec0.50.72.2-1.11.2-1.1-0.5-0.5-0.7-1.5-0.7-1.0-1.5-0.50.2-0.90.90.3-0.30.90.4-0.00.4
Patch foraging time to switch 0 sec0.00.10.20.4-0.30.20.2-0.10.20.50.20.20.40.3-0.2-0.20.20.2-0.3-0.1-0.5-0.10.4
Patch foraging water rate 0 sec0.10.31.20.3-0.50.60.50.80.3-0.00.10.20.30.0-0.21.1-1.10.4-0.3-0.90.5-0.0-0.1
Patch foraging water rate 12 sec0.81.64.4-0.70.2-0.20.20.0-0.5-0.5-1.0-1.41.4-1.01.41.9-1.9-1.41.1-2.02.11.61.0
Patch foraging water rate 18 sec0.20.21.7-0.6-0.10.1-0.5-0.1-0.5-0.5-0.6-0.10.0-0.50.40.6-0.6-0.10.1-0.41.30.50.2
Patch foraging water rate 24 sec0.50.82.20.9-1.11.11.51.20.90.00.80.80.90.7-0.51.2-1.20.6-0.5-1.0-0.2-0.3-0.4
Patch foraging water rate 6 sec0.50.72.0-1.00.4-0.3-0.7-0.8-0.8-0.2-0.7-0.60.4-1.01.10.5-0.5-1.21.3-0.51.11.4-0.4
Seeking ratio, delayed vs. immediate footshock1.01.22.5-1.11.2-1.1-1.6-1.2-1.6-1.3-1.3-0.9-0.5-1.51.2-0.00.0-1.21.10.00.80.90.7
Distance traveled before self-admin0.30.40.9-0.70.9-0.8-0.8-0.7-0.70.2-0.6-0.5-0.1-0.70.60.2-0.2-0.80.90.10.60.50.7
Distance traveled after self-admin0.30.41.6-0.20.00.10.2-0.0-0.50.2-0.3-1.10.6-0.60.41.3-1.3-0.10.2-0.70.30.60.5
Extensor digitorum longus weight0.31.12.71.1-1.51.50.91.10.81.30.70.91.50.5-0.41.6-1.60.3-0.4-1.6-0.0-0.10.6
Bone: elastic displacement0.50.62.30.3-0.40.41.00.80.30.50.0-0.51.20.00.21.5-1.5-0.40.3-1.40.90.30.8
Bone: elastic work2.43.15.42.1-2.32.32.32.31.82.01.41.22.21.4-1.32.1-2.11.1-1.4-2.1-0.2-0.70.4
Bone: endosteal estimation2.04.48.42.7-2.82.82.32.22.22.51.71.82.91.4-1.32.8-2.80.9-1.2-2.7-0.5-0.30.5
Bone: endosteal perimeter1.83.711.41.7-2.32.31.31.41.32.40.71.03.40.4-0.23.3-3.3-0.2-0.3-3.40.80.81.2
Epididymis fat weight0.72.45.61.8-1.71.81.21.21.90.91.82.4-0.02.1-1.9-0.10.11.9-1.80.4-1.9-1.8-0.1
Delta time in closed arm before/after self-admin0.60.62.1-0.20.7-0.60.2-0.1-0.2-0.6-0.1-0.5-1.40.3-0.3-1.41.40.9-0.61.4-0.7-0.70.6
Delta time in open arm before/after self-admin2.01.96.70.5-0.70.71.10.80.21.6-0.0-1.02.6-0.60.72.3-2.3-1.51.2-2.61.31.20.2
Diff in mean of infusions in LGA sessions0.60.72.30.3-0.20.20.40.40.2-0.10.60.9-1.50.7-1.0-1.21.21.2-0.91.4-1.1-1.0-0.4
Delay discount exponential model param1.31.54.80.8-1.31.31.01.30.81.90.70.71.80.3-0.22.2-2.2-0.30.1-2.00.40.3-0.3
Extinction: sum of active levers before priming1.21.43.51.0-1.00.91.31.11.5-0.51.30.5-0.71.6-1.4-0.70.71.5-1.40.7-1.9-1.6-0.6
Active lever presses in extinction session 60.90.81.91.0-1.11.00.70.91.00.10.90.9-0.41.2-1.3-0.30.31.2-1.30.5-1.0-1.4-0.3
Bone: final force0.91.42.91.3-1.11.10.90.91.20.51.41.3-0.41.5-1.7-0.90.91.7-1.60.7-1.6-1.5-0.7
Bone: final moment1.22.03.91.6-1.21.21.21.21.50.61.61.5-0.41.8-1.9-0.80.82.0-1.90.7-1.8-1.8-0.9
Food consumed during 24 hour testing period1.31.82.91.6-1.41.41.31.71.61.61.61.50.61.5-1.60.5-0.51.4-1.5-0.3-1.3-1.4-0.7
Glucose0.81.32.5-1.61.3-1.3-1.5-1.4-1.4-0.9-1.1-0.9-1.4-0.90.9-1.51.5-0.50.61.50.30.3-0.2
Heart weight2.64.17.22.6-2.22.12.72.42.31.12.42.10.42.5-2.50.4-0.42.5-2.6-0.1-2.2-2.3-0.9
Delay discount hyperbolic model param1.31.54.90.7-1.21.30.91.20.91.90.70.81.80.2-0.12.2-2.2-0.30.1-2.10.40.3-0.2
Intermittent access intake day 1-15 change0.30.61.9-0.80.3-0.3-1.4-1.1-0.70.0-0.8-0.10.5-0.91.00.4-0.4-1.00.9-0.51.11.20.8
Intermittent access intake escalation0.40.81.9-0.90.4-0.3-1.4-1.1-0.8-0.0-1.0-0.40.5-1.01.10.5-0.5-1.21.0-0.51.21.30.9
Intermittent access intake escalation 21.01.13.4-1.51.0-0.9-1.8-1.5-1.3-0.6-1.3-0.3-0.6-1.11.0-0.50.5-0.80.80.41.31.11.1
Intermitt. access day 1 inactive lever presses0.20.61.40.8-0.50.50.80.80.80.81.00.4-0.11.1-1.1-0.70.71.0-0.90.6-0.8-1.2-0.7
Intermitt. access day 15 inactive lever presses0.40.91.80.8-0.20.20.70.60.80.21.01.0-0.61.1-1.2-1.21.21.1-1.01.1-1.4-1.3-0.3
Intermitt. access escalation Index0.40.62.0-0.50.9-1.0-0.6-0.7-0.7-1.0-0.7-1.4-0.7-0.60.6-0.60.6-0.80.80.50.30.30.7
Intermittent access day 1 total infusions0.50.92.51.2-1.01.00.91.20.91.61.00.71.20.5-0.51.1-1.10.00.1-1.0-0.5-0.5-1.0
Intermittent access day 15 total infusions0.50.71.9-0.1-0.10.1-0.5-0.2-0.30.9-0.3-0.31.4-0.80.91.2-1.2-1.31.3-1.20.71.00.1
Intermittent access terminal intake (last 3 days)0.30.41.50.4-0.40.4-0.20.10.11.10.10.21.2-0.30.30.9-0.9-0.60.6-1.00.30.4-0.0
Intermittent access total infusions0.50.62.50.8-0.70.70.20.50.41.40.40.51.6-0.00.11.0-1.0-0.60.6-1.2-0.10.2-0.7
Intermittent access day 1 locomotion0.10.20.80.00.1-0.20.20.1-0.20.5-0.1-0.40.7-0.30.40.3-0.3-0.70.9-0.50.20.3-0.2
Intermittent access day 15 total locomotion0.61.14.10.9-1.11.10.60.90.51.60.50.32.00.00.11.8-1.8-0.70.6-1.80.40.2-0.5
Intermittent access total locomotion1.11.44.91.3-1.31.31.01.21.01.90.90.92.20.5-0.31.5-1.5-0.20.2-1.7-0.3-0.1-0.9
Intermittent access standard deviation0.20.41.40.9-0.70.70.10.40.71.10.71.20.60.7-0.7-0.00.00.5-0.5-0.1-0.7-0.50.0
Left kidney weight10.549.087.89.4-8.88.88.78.78.57.77.97.06.17.2-6.85.4-5.45.5-5.8-4.8-5.5-5.4-1.9
Right kidney weight12.255.693.99.7-9.09.09.39.39.27.48.88.25.28.3-7.84.4-4.46.8-7.0-3.7-6.5-6.6-2.7
Cocaine induced anxiety1.82.69.11.7-1.31.31.31.42.00.32.03.0-0.22.0-1.9-0.50.51.6-1.80.4-2.1-1.9-1.7
Post-drug Anxiety1.01.12.50.30.0-0.00.20.10.7-1.00.71.6-1.21.0-1.0-1.61.61.0-1.21.3-1.3-1.2-1.0
Baseline Anxiety2.22.66.8-2.01.9-1.9-1.4-1.8-2.0-1.2-2.1-2.6-0.6-1.81.8-0.50.5-1.51.50.41.71.61.1
Tail length0.52.14.4-1.81.6-1.5-1.3-1.5-1.4-0.9-1.6-1.80.1-1.72.00.1-0.1-2.02.1-0.41.41.80.6
Length with tail0.10.51.40.6-0.70.70.60.70.60.90.50.81.00.30.01.2-1.2-0.20.1-1.1-0.10.1-0.1
Length without tail1.34.37.52.5-2.32.42.22.42.41.42.42.50.02.4-2.60.4-0.42.7-2.70.1-2.1-2.5-0.6
Times rat made contact with spout0.50.61.40.6-0.50.50.80.90.90.51.11.00.01.0-0.9-0.10.10.6-0.60.4-1.2-1.0-1.1
Lifetime Intake0.60.82.81.0-0.91.00.40.80.61.70.60.61.70.2-0.11.1-1.1-0.40.4-1.3-0.20.0-0.6
Liver weight, left0.50.93.61.1-1.51.50.60.90.71.91.01.01.20.7-0.50.8-0.8-0.10.2-0.6-0.5-0.4-0.5
Liver weight, right0.40.63.30.9-1.21.10.10.50.31.80.60.71.20.2-0.10.5-0.5-0.80.9-0.5-0.6-0.1-0.8
Locomotor activity0.61.02.51.2-1.31.31.21.20.81.60.70.41.40.7-0.71.2-1.20.7-0.9-1.2-0.1-0.40.1
Locomotor testing distance0.20.40.8-0.70.7-0.7-0.7-0.6-0.9-0.2-0.8-0.9-0.1-0.80.6-0.10.1-0.40.20.00.90.60.5
Locomotor testing rearing0.10.20.90.3-0.20.10.30.40.10.8-0.1-0.30.9-0.10.20.5-0.5-0.40.2-0.70.60.10.0
Locomotion in novel chamber2.02.56.2-1.00.9-1.1-0.8-1.1-1.50.1-1.5-1.81.7-1.92.01.6-1.6-2.52.3-1.71.62.11.0
Locomotion in novel chamber post-restriction0.30.41.8-0.10.2-0.3-1.4-0.9-1.1-0.1-0.8-0.6-0.2-0.90.50.0-0.0-0.30.6-0.10.50.61.3
Fecal boli incidents, locomotor time 10.50.72.30.9-1.21.00.71.10.80.70.80.20.80.6-0.70.7-0.70.6-0.6-0.6-0.7-0.7-1.5
Change in fecal boli incidents, locomotor task0.60.62.3-0.60.4-0.3-0.3-0.3-0.30.1-0.5-0.20.3-0.70.80.9-0.9-1.00.9-1.11.51.21.0
Time >=10cm from walls, locomotor time 10.40.41.10.7-0.70.70.50.60.70.60.90.80.10.7-0.80.1-0.10.9-0.7-0.1-1.1-0.6-0.3
Bouts of movement, locomotor time 10.50.61.50.7-0.60.50.00.30.4-0.10.40.9-0.90.7-0.9-1.01.01.2-1.00.8-1.0-1.10.5
Total resting periods, locomotor time 10.91.02.80.6-0.30.20.00.10.4-0.50.41.0-1.30.9-1.0-1.71.71.4-1.21.4-1.4-1.30.2
Rest time, locomotor task time 10.81.01.71.2-1.00.91.21.11.30.51.21.20.31.3-1.20.0-0.01.3-1.2-0.2-1.1-0.8-0.3
Distance moved, locomotor task time 10.10.10.40.10.2-0.2-0.6-0.2-0.60.3-0.4-0.4-0.1-0.50.10.0-0.0-0.20.00.00.2-0.00.1
Vertical activity count, locomotor time 10.10.30.8-0.70.6-0.5-0.9-0.8-0.8-0.7-0.7-0.2-0.9-0.60.4-0.70.7-0.10.00.60.40.30.1
Time >=10cm from walls, locomotor time 20.20.20.7-0.80.6-0.7-0.6-0.6-0.1-0.7-0.2-0.10.0-0.40.60.3-0.3-0.60.3-0.40.70.80.0
Bouts of movement, locomotor time 20.71.13.80.10.00.1-0.3-0.10.1-0.70.30.9-2.00.7-0.9-1.91.91.0-0.81.7-1.3-1.4-0.0
Total resting periods, locomotor time 20.81.44.90.20.00.1-0.3-0.00.2-0.80.41.0-2.20.9-1.1-2.12.11.2-1.01.9-1.5-1.60.0
Rest time, locomotor task time 20.20.31.1-0.60.7-0.60.0-0.4-0.3-0.8-0.3-0.6-0.5-0.10.2-1.01.0-0.20.40.70.00.2-0.5
Distance moved, locomotor task time 21.01.25.11.0-1.00.90.50.90.61.60.50.51.70.1-0.12.3-2.3-0.1-0.2-1.70.40.20.7
Vertical activity count, locomotor time 20.71.03.80.7-1.00.90.50.70.81.30.51.11.60.20.01.9-1.9-0.1-0.3-1.70.50.50.3
Light reinforcement 10.61.66.10.6-0.70.81.00.80.31.30.0-0.42.3-0.40.52.5-2.5-0.70.5-2.41.01.00.5
Light reinforcement 20.91.44.51.1-1.21.31.21.11.11.50.90.62.10.6-0.32.0-2.0-0.1-0.2-2.00.10.20.1
Bone: marrow area2.14.58.02.7-2.82.82.32.32.22.51.81.92.81.5-1.42.8-2.81.0-1.3-2.7-0.6-0.50.4
Bone: maximum diameter2.75.09.52.8-3.13.12.32.52.42.61.92.02.91.7-1.62.9-2.91.3-1.5-2.7-0.5-0.70.3
Bone: maximum force1.12.03.61.7-1.61.61.41.41.61.01.61.50.11.7-1.9-0.20.21.9-1.90.2-1.7-1.6-0.6
Bone: maximum moment1.52.74.92.0-1.71.71.71.71.91.02.01.70.12.1-2.2-0.10.12.2-2.20.2-1.9-1.9-0.8
Mean time between licks in bursts1.33.16.4-2.51.9-1.9-2.3-2.2-2.1-1.3-2.1-1.4-0.6-2.02.1-0.40.4-1.91.80.31.92.01.2
Mean num. licks in bursts2.03.15.82.0-1.61.61.71.82.11.42.42.40.22.3-2.2-0.20.21.6-1.60.6-2.4-2.2-1.2
Cd content in liver0.10.10.40.5-0.30.30.20.3-0.10.3-0.00.20.6-0.20.00.6-0.6-0.0-0.1-0.40.20.1-0.0
Co content in liver0.10.10.3-0.30.3-0.30.30.0-0.3-0.1-0.3-0.50.4-0.40.40.5-0.5-0.30.3-0.30.40.50.1
Cu content in liver3.84.59.4-2.82.6-2.6-2.4-2.6-2.3-3.1-2.5-1.8-1.5-2.22.1-0.80.8-1.71.40.42.22.12.2
Fe content in liver0.20.21.10.7-0.20.20.70.50.2-0.00.20.10.00.3-0.60.3-0.31.1-1.0-0.1-0.0-0.40.1
K content in liver0.20.20.40.5-0.60.60.60.50.50.50.4-0.00.40.4-0.30.6-0.60.3-0.1-0.4-0.0-0.10.3
Mg content in liver0.10.10.9-0.1-0.00.00.10.00.2-0.30.10.1-0.40.3-0.3-0.40.40.4-0.40.3-0.1-0.31.0
Mn content in liver0.60.62.00.7-1.01.01.00.80.71.20.4-0.01.40.30.01.1-1.1-0.40.6-1.10.10.2-0.1
Na content in liver0.91.02.4-1.20.8-0.8-1.5-1.3-1.3-0.8-1.2-1.2-1.0-1.10.7-0.40.4-0.40.50.51.00.81.5
Rb content in liver0.50.61.6-0.20.5-0.50.30.10.1-1.20.20.4-1.30.4-0.6-1.01.01.0-1.21.0-0.7-0.80.4
Se content in liver0.30.40.9-0.30.6-0.6-0.4-0.5-0.5-0.7-0.6-0.60.2-0.70.70.5-0.5-0.61.0-0.40.80.9-0.8
Sr content in liver0.40.30.7-0.50.6-0.6-0.9-0.8-0.6-0.2-0.5-0.3-0.3-0.50.5-0.60.6-0.60.80.50.30.4-0.4
Zn content in liver0.20.20.80.2-0.70.70.50.60.50.70.40.20.90.3-0.00.5-0.5-0.50.2-0.60.1-0.00.4
Bone: minimum diameter1.11.96.60.6-1.31.30.10.30.21.8-0.3-0.32.6-0.50.72.4-2.4-1.00.7-2.61.41.41.2
Time in familiar zone, hab. session 10.50.50.80.6-0.90.90.80.80.60.90.2-0.30.80.4-0.40.9-0.90.5-0.6-0.90.4-0.10.8
Time in novel zone, hab. session 10.20.20.5-0.40.7-0.7-0.6-0.6-0.7-0.6-0.50.1-0.4-0.60.5-0.40.4-0.50.50.30.10.3-0.2
Total zone transitions, hab. session 10.91.32.2-1.41.2-1.2-1.4-1.3-1.5-1.0-1.2-1.0-1.3-1.10.9-1.31.3-0.81.01.10.80.50.4
Total locomotion distance, hab. session 10.20.31.00.4-0.40.50.20.30.00.8-0.00.21.0-0.20.30.7-0.7-0.90.9-0.90.40.4-0.1
Locomotion velocity, hab. session 10.20.31.10.5-0.60.60.40.40.20.90.10.31.1-0.00.20.6-0.6-0.80.8-0.90.30.3-0.1
Time in familiar zone, hab. session 20.30.31.0-0.40.8-0.80.1-0.2-0.2-0.4-0.4-0.90.4-0.40.70.2-0.2-1.00.8-0.50.80.70.0
Time in novel zone, hab. session 20.10.10.40.00.1-0.1-0.3-0.1-0.3-0.2-0.10.5-0.6-0.1-0.2-0.50.50.4-0.20.6-0.3-0.4-0.3
Total zone transitions, hab. session 20.50.61.50.9-1.21.21.01.00.80.60.80.2-0.10.9-1.0-0.10.11.2-1.10.1-0.6-1.00.2
Total locomotion distance, hab. session 20.30.41.20.8-1.11.10.90.80.60.80.50.20.70.4-0.40.7-0.70.3-0.3-0.8-0.1-0.20.2
Locomotion velocity, hab. session 20.20.31.00.7-1.01.00.80.70.50.70.50.20.50.4-0.40.4-0.40.3-0.3-0.5-0.2-0.30.1
Novel to familiar place preference ratio0.20.20.50.4-0.40.50.40.40.40.20.40.70.40.2-0.10.7-0.7-0.20.2-0.4-0.2-0.1-0.4
Novelty place preference0.30.31.20.5-0.60.60.50.60.50.50.40.60.90.10.01.1-1.1-0.40.4-0.8-0.00.0-0.4
Time in novel zone, NPP test0.30.41.10.6-0.60.60.60.70.50.50.40.60.90.10.01.1-1.1-0.50.5-0.80.00.0-0.4
Total zone transitions, NPP test0.10.10.4-0.1-0.10.00.0-0.0-0.3-0.2-0.1-0.7-0.6-0.10.0-0.30.3-0.00.20.40.1-0.20.3
Total locomotion distance, NPP test0.30.51.30.6-0.90.80.80.70.20.70.1-0.21.0-0.00.01.1-1.1-0.30.3-1.10.40.20.6
Locomotion velocity, NPP test0.20.31.00.2-0.60.50.40.3-0.00.6-0.0-0.30.9-0.20.31.0-1.0-0.50.5-1.00.50.40.8
Intraocular pressure0.10.20.90.2-0.50.5-0.3-0.00.00.90.10.10.6-0.20.30.5-0.5-0.40.5-0.3-0.50.10.9
Delta distance traveled before/after self-admin0.80.82.30.6-1.01.11.50.90.50.60.4-0.61.50.1-0.01.5-1.50.3-0.4-1.40.20.3-0.6
Delta ambulatory time before/after self-admin0.50.61.70.5-0.90.91.30.90.40.20.2-1.01.00.1-0.11.3-1.30.4-0.5-1.00.20.1-0.3
Parametrial fat weight0.71.62.8-1.61.1-1.2-1.7-1.7-1.6-0.6-1.6-1.2-0.3-1.41.5-0.90.9-1.51.50.41.61.30.6
Pavlov. Cond. lever latency1.01.33.51.1-0.40.41.51.11.3-0.21.41.9-0.21.3-1.3-0.30.31.2-1.20.3-1.6-1.1-1.5
Pavlov. Cond. magazine entry latency1.51.94.0-1.81.4-1.4-2.0-1.8-1.8-1.3-1.6-1.4-1.6-1.41.1-1.21.2-0.50.71.40.90.71.0
Pavlov. Cond. change in total contacts1.71.84.1-1.61.3-1.3-2.0-1.8-1.7-1.5-1.6-1.4-1.7-1.30.9-1.21.2-0.00.21.30.90.61.2
Pavlov. Cond. index score1.21.53.8-1.61.1-1.1-1.9-1.6-1.6-0.8-1.5-1.6-1.2-1.31.1-0.80.8-0.50.71.01.10.71.4
Pavlov. Cond. latency score1.11.33.5-1.30.8-0.8-1.8-1.4-1.5-0.4-1.5-1.9-0.7-1.31.1-0.30.3-0.60.80.51.40.81.7
Pavlov. Cond. lever contacts1.62.04.3-1.50.8-0.8-2.0-1.6-1.8-0.1-1.8-2.1-0.2-1.71.60.1-0.1-1.41.50.11.81.41.9
Pavlov. Cond. magazine entry number1.72.25.51.8-1.51.52.32.01.81.51.61.21.91.5-1.11.3-1.30.5-0.8-1.6-0.8-0.6-1.0
Pavlov. Cond. intertrial magazine entries0.40.42.1-0.71.1-1.1-0.3-0.6-0.6-1.4-0.5-0.9-0.9-0.40.3-0.40.4-0.10.30.40.20.20.3
Pavlov. Cond. lever-magazine prob. diff.1.51.84.3-1.81.3-1.3-2.1-1.7-1.7-0.9-1.6-1.7-1.3-1.51.2-0.80.8-0.70.91.01.20.81.4
Pavlov. Cond. response bias1.82.25.5-2.01.4-1.4-2.4-2.0-2.0-1.2-1.8-1.5-1.5-1.71.4-1.01.0-0.81.11.21.21.01.3
Pavlov. Cond. lever latency0.60.72.0-1.21.3-1.4-0.8-1.0-1.0-0.5-0.8-0.7-0.3-0.81.1-0.50.5-1.21.10.30.50.80.1
Pavlov. Cond. magazine entry latency0.50.62.2-0.00.2-0.2-0.2-0.10.1-1.40.10.7-1.50.4-0.8-0.90.91.3-1.21.1-0.5-0.90.1
Pavlov. Cond. change in total contacts0.91.45.51.1-1.11.20.91.01.00.10.90.9-0.71.2-1.7-0.30.32.3-2.20.6-0.9-1.50.1
Pavlov. Cond. index score0.30.51.80.6-0.70.70.20.40.5-0.30.50.7-0.70.6-1.0-0.30.31.4-1.30.5-0.5-0.90.0
Pavlov. Cond. latency score0.40.52.10.7-0.70.80.20.40.5-0.30.50.8-0.60.6-1.1-0.20.21.4-1.40.4-0.6-0.90.1
Pavlov. Cond. lever contacts0.50.71.61.1-1.11.20.70.90.90.20.80.7-0.10.8-1.10.1-0.11.3-1.20.0-0.6-0.9-0.3
Pavlov. Cond. magazine entry number0.30.31.3-0.50.5-0.5-0.2-0.4-0.40.3-0.4-0.60.6-0.50.90.2-0.2-1.21.1-0.50.40.80.3
Pavlov. Cond. intertrial magazine entries0.81.23.41.2-0.90.80.80.81.10.81.30.9-0.41.3-1.4-0.70.71.4-1.40.7-1.9-1.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.40.6-0.70.70.30.40.5-0.30.40.7-0.50.6-0.9-0.10.11.2-1.10.3-0.4-0.70.1
Pavlov. Cond. response bias0.40.51.90.7-0.60.70.40.50.6-0.30.50.6-0.80.7-1.1-0.40.41.4-1.20.6-0.6-0.9-0.3
Time in closed arm before self-admin2.22.85.7-2.42.2-2.3-2.4-2.2-1.9-1.9-1.9-1.1-1.0-1.91.7-0.50.5-1.61.50.41.71.60.3
Time in closed arm after self-admin1.92.04.3-1.82.1-2.0-1.6-1.8-1.8-1.0-1.8-1.4-0.8-1.71.5-0.80.8-1.21.20.61.11.31.2
Time in open arm before self-admin0.20.20.80.7-0.80.8-0.10.30.10.80.30.90.50.1-0.30.4-0.40.3-0.1-0.2-0.3-0.20.2
Time in open arm after self-admin2.02.24.51.7-2.02.01.81.81.61.51.21.02.10.9-0.72.1-2.1-0.1-0.2-2.1-0.1-0.3-0.3
Bone: periosteal estimation1.43.06.02.2-2.42.41.71.81.72.11.41.52.51.1-1.12.3-2.30.7-1.0-2.3-0.3-0.30.3
Bone: periosteal perimeter1.52.68.51.3-1.91.91.01.21.02.10.50.62.90.20.02.9-2.9-0.3-0.1-2.90.90.70.9
Bone: post-yield work1.31.84.60.30.1-0.10.50.20.6-1.00.90.8-2.01.2-1.5-2.02.02.0-1.62.1-1.8-1.7-1.1
Progressive ratio test 1 active lever presses0.10.10.70.4-0.00.00.00.10.20.30.40.10.30.1-0.0-0.20.2-0.40.6-0.0-0.6-0.2-0.8
Progressive ratio test 1 breakpoint0.10.10.50.20.2-0.2-0.2-0.10.10.10.20.00.1-0.00.1-0.30.3-0.50.70.1-0.5-0.1-0.7
Progressive ratio test 1 inactive lever presses0.20.31.60.8-0.50.30.90.60.61.30.60.20.90.5-0.30.0-0.0-0.00.1-0.2-0.6-0.4-0.5
Progressive ratio test 2 active lever presses1.41.63.51.7-1.21.21.41.61.60.81.71.20.41.4-1.50.1-0.11.0-0.80.0-1.5-1.6-1.9
Progressive ratio test 2 breakpoint1.21.32.91.5-1.11.11.31.41.40.81.61.10.51.3-1.30.1-0.10.8-0.7-0.0-1.4-1.4-1.7
Progressive ratio test 2 inactive lever presses0.20.31.21.1-0.80.70.20.70.70.90.70.50.40.5-0.50.2-0.2-0.00.1-0.2-0.4-0.6-0.6
Incentive Sensitization - Responses1.72.34.41.8-1.31.32.02.01.90.62.01.30.11.9-1.8-0.10.11.6-1.50.3-1.8-2.1-1.8
Incentive Sensitization - Breakpoint2.12.74.81.9-1.41.42.12.12.10.82.11.50.22.0-2.0-0.10.11.7-1.60.2-1.9-2.2-1.8
Sum of active levers in priming session hrs 5-60.30.20.90.6-0.70.61.00.60.50.30.4-0.00.30.5-0.40.2-0.20.5-0.5-0.4-0.6-0.3-0.2
Progressive ratio0.20.41.9-0.80.6-0.5-0.8-0.6-0.4-0.4-0.1-0.1-1.4-0.0-0.1-0.80.80.2-0.01.2-0.4-0.30.0
Food seeking constrained by brief footshock0.20.21.00.4-0.70.30.60.5-0.00.30.1-1.00.30.3-0.40.3-0.30.7-0.5-0.0-0.0-0.2-0.1
Seeking ratio, punishment vs. effort0.30.41.01.0-1.00.81.00.80.50.20.4-0.20.60.6-0.70.1-0.10.9-0.9-0.4-0.1-0.4-0.2
Retroperitoneal fat weight1.87.512.93.6-3.53.62.73.03.52.73.13.21.33.1-3.21.1-1.12.9-3.0-0.9-2.5-2.6-0.8
Reaction time number correct0.40.82.6-1.00.6-0.5-1.5-0.6-1.0-0.3-1.0-0.40.1-1.11.10.7-0.7-1.31.0-0.51.60.8-0.2
Reaction time mean minus median0.00.10.40.10.1-0.0-0.10.0-0.1-0.1-0.1-0.6-0.2-0.30.10.4-0.4-0.00.1-0.10.00.10.4
Reaction time mean minus median AUC0.20.61.31.1-1.01.00.71.00.80.90.80.50.70.5-0.61.1-1.10.3-0.2-0.8-0.5-0.40.1
Reaction time num false alarms0.81.12.4-0.80.4-0.4-1.2-0.9-1.40.2-1.2-1.30.5-1.61.30.7-0.7-1.51.4-0.51.31.4-0.1
Reaction time num false alarms AUC0.60.91.9-0.50.1-0.1-0.9-0.6-1.20.5-1.0-1.40.6-1.41.10.8-0.8-1.41.4-0.61.21.2-0.3
Reaction time trials correct on left0.40.82.6-1.00.6-0.5-1.5-0.6-1.0-0.3-1.0-0.40.1-1.11.10.7-0.7-1.31.0-0.51.60.8-0.2
Reaction time trials on left0.40.82.6-1.00.6-0.6-1.5-0.6-1.0-0.3-1.0-0.40.0-1.11.10.7-0.7-1.31.1-0.51.60.8-0.2
Reaction time mean0.30.52.0-0.40.7-0.7-0.4-0.6-0.5-1.2-0.2-0.4-1.4-0.2-0.1-1.01.00.3-0.11.2-1.0-0.30.0
Reaction time mean AUC0.30.41.8-0.30.5-0.5-0.4-0.5-0.4-1.0-0.0-0.2-1.3-0.1-0.1-0.90.90.20.01.1-1.1-0.30.0
Median of all reaction times0.60.93.2-0.50.9-0.9-0.4-0.7-0.6-1.5-0.2-0.3-1.8-0.1-0.1-1.41.40.5-0.21.6-1.2-0.4-0.1
Reaction time omissions0.30.41.4-0.60.9-0.9-0.3-0.5-0.5-1.0-0.5-0.8-1.2-0.40.3-0.80.8-0.10.20.9-0.1-0.0-0.0
Reaction time false alarm rate0.20.20.9-0.1-0.0-0.0-0.2-0.3-0.70.5-0.5-1.00.4-0.70.50.3-0.3-0.60.7-0.20.30.7-0.1
Reaction time premature initiation rate2.13.06.91.5-1.01.11.51.72.0-0.01.92.6-1.02.2-2.4-0.80.82.5-2.60.9-1.4-2.4-1.1
Reaction time premature initiations0.81.44.60.9-0.60.70.61.21.3-0.21.22.2-0.91.5-1.6-0.40.41.6-1.80.6-0.5-1.7-1.1
Std. dev. reaction times0.00.10.40.10.3-0.20.0-0.1-0.1-0.50.0-0.7-0.5-0.2-0.0-0.10.1-0.10.20.3-0.5-0.10.0
Reaction time trials completed0.40.82.6-1.00.6-0.6-1.5-0.6-1.0-0.3-1.0-0.40.0-1.11.10.7-0.7-1.31.1-0.51.60.8-0.2
Reaction time trials AUC0.30.62.1-0.70.3-0.3-1.3-0.4-0.8-0.1-0.8-0.30.1-0.90.80.7-0.7-1.10.8-0.61.50.6-0.3
Run reversals in cocaine runway, females2.62.64.4-2.11.8-2.0-1.5-1.9-1.9-1.1-1.9-1.50.1-1.92.1-0.40.4-2.11.9-0.21.72.1-0.3
Run reversals in cocaine runway, males0.80.82.51.0-1.01.10.40.70.31.40.30.11.3-0.1-0.21.6-1.6-0.30.4-1.40.20.30.6
Latency to leave start box in cocaine runway0.70.81.81.1-0.80.91.21.11.01.30.91.10.90.8-0.70.6-0.60.5-0.5-0.7-0.5-0.60.5
Latency to leave start box in cocaine runway, F0.40.41.00.8-0.60.70.90.90.70.90.71.00.30.7-0.60.2-0.20.7-0.6-0.2-0.5-0.7-0.2
Latency to leave start box in cocaine runway, M0.50.51.30.8-0.50.50.90.70.91.10.60.61.10.4-0.20.7-0.7-0.1-0.1-1.0-0.4-0.00.7
Std. dev. time between licks in bursts0.10.20.7-0.10.4-0.4-0.4-0.4-0.1-0.8-0.2-0.2-0.8-0.0-0.3-0.20.20.7-0.70.3-0.0-0.00.2
Total sessions with >9 infusions1.92.35.82.0-1.91.91.61.91.72.41.51.01.71.2-1.21.6-1.61.0-0.9-1.4-0.9-0.9-0.3
Short access day 1 total inactive lever presses1.92.55.71.9-2.01.92.42.11.70.91.70.80.71.5-1.80.9-0.92.1-1.8-0.4-1.5-1.6-1.4
Short access day 10 total inactive lever presses0.41.02.51.3-1.21.11.61.41.11.21.00.11.01.1-1.10.5-0.51.0-1.1-0.6-0.7-1.0-0.3
Short access day 1 total infusions0.40.51.90.8-0.90.90.90.90.51.40.6-0.30.70.4-0.60.6-0.60.6-0.3-0.6-0.5-0.4-0.3
Short access day 10 total infusions0.20.31.50.7-0.60.6-0.10.30.51.20.50.90.80.2-0.30.3-0.3-0.10.2-0.6-0.3-0.1-0.6
Short access total infusions0.91.23.31.5-1.41.41.01.31.21.81.20.81.10.9-1.00.9-0.90.8-0.6-0.9-0.9-0.7-0.5
Short access day 1 locomotion0.10.10.60.4-0.20.20.80.40.30.70.4-0.10.70.3-0.2-0.00.00.10.0-0.3-0.3-0.1-0.7
Short access day 10 total locomotion0.30.51.6-0.90.7-0.5-0.7-0.7-0.80.9-0.7-0.60.5-0.81.0-0.30.3-1.11.3-0.10.60.8-0.4
Short access total locomotion0.10.21.0-0.10.2-0.2-0.0-0.1-0.21.0-0.2-0.40.8-0.30.50.2-0.2-0.50.6-0.50.30.4-0.0
One hour access (0.3 mA shock)0.70.82.50.9-0.81.0-0.10.50.51.50.61.01.6-0.00.11.4-1.4-0.70.6-1.30.10.2-0.3
Compulsive drug intake0.70.82.81.0-0.90.90.70.90.70.30.80.1-0.90.9-1.20.1-0.11.7-1.50.5-0.9-1.10.2
One hour access (shock baseline)0.61.03.5-0.1-0.10.2-0.7-0.3-0.21.0-0.20.51.9-0.81.01.1-1.1-1.81.6-1.50.71.0-0.5
Social response proportion0.30.30.60.5-0.50.50.50.60.60.70.50.70.70.3-0.30.7-0.70.3-0.3-0.7-0.5-0.2-0.5
Social responses0.40.62.20.3-0.40.30.30.50.61.10.30.61.2-0.00.21.5-1.5-0.40.2-1.40.30.5-0.5
Social time1.52.04.7-2.02.2-2.2-1.6-1.6-1.7-1.6-1.2-0.7-1.7-1.21.2-1.41.4-0.91.11.60.10.5-0.7
Soleus weight0.72.04.11.5-1.51.51.11.11.20.51.61.4-0.71.8-1.9-1.01.02.0-1.71.1-1.9-1.8-0.9
Bone: stiffness0.40.72.00.10.1-0.1-0.3-0.30.1-0.50.20.3-1.20.5-0.9-1.31.31.4-1.31.2-0.8-0.8-0.0
Tibialis anterior weight0.00.10.2-0.2-0.10.1-0.0-0.1-0.1-0.5-0.10.3-0.40.0-0.1-0.20.20.5-0.30.2-0.1-0.00.5
Time to tail flick, vehicle, before self-admin0.40.41.40.5-0.20.10.60.50.90.10.80.6-0.20.9-0.9-0.60.60.6-0.40.5-0.5-0.7-1.2
Time to tail flick, vehicle, after self-admin0.10.10.50.2-0.30.1-0.2-0.1-0.0-0.4-0.20.20.0-0.1-0.00.2-0.2-0.40.3-0.30.70.2-0.3
Time to tail flick, test, before self-admin0.20.21.70.2-0.20.1-0.6-0.4-0.31.3-0.2-0.10.6-0.20.20.2-0.2-0.40.3-0.30.20.40.8
Time to tail flick, test, after self-admin0.40.41.1-0.40.5-0.7-0.6-0.7-0.8-1.1-0.8-0.7-0.7-0.60.2-0.70.7-0.10.10.50.20.20.7
Delta time to tail flick, vehicle, before/after SA0.80.82.01.2-1.41.40.71.00.80.30.81.1-0.10.9-1.20.4-0.41.2-1.3-0.1-0.7-1.0-0.3
Delta time to tail flick, test, before/after SA0.50.53.8-0.90.8-0.8-0.1-0.5-0.6-2.0-0.7-0.8-0.9-0.50.3-0.60.6-0.00.00.60.60.2-0.1
Tibia length0.10.20.50.5-0.70.70.70.60.5-0.00.4-0.10.10.4-0.40.4-0.40.5-0.5-0.3-0.1-0.4-0.2
Ambulatory time before self-admin0.30.41.0-0.40.7-0.6-0.4-0.4-0.70.6-0.5-1.00.3-0.80.70.6-0.6-0.91.0-0.20.40.60.6
Ambulatory time after self-admin0.80.95.0-0.80.8-0.80.0-0.5-0.9-0.7-1.0-2.20.2-1.11.01.0-1.0-0.70.7-0.50.91.10.8
Bone: tissue strength0.40.41.00.40.0-0.00.70.30.6-0.70.50.4-0.80.8-0.8-0.80.81.0-0.90.6-0.7-0.7-0.3
Total heroin consumption1.61.93.51.5-1.91.81.21.61.70.81.61.2-0.11.8-1.80.5-0.51.7-1.7-0.0-1.2-1.6-0.2
Bone: trabecular number1.22.03.8-2.01.8-1.8-1.6-1.7-1.6-1.3-1.6-1.8-0.7-1.61.6-0.80.8-1.21.20.51.41.30.4
Bone: trabecular spacing2.63.46.72.3-2.62.61.82.22.12.21.91.61.31.8-1.91.8-1.81.8-1.9-1.3-1.0-1.50.2
Bone: trabecular thickness0.30.30.7-0.80.8-0.8-0.4-0.6-0.8-0.4-0.6-0.5-0.1-0.70.7-0.40.4-0.70.70.20.40.6-0.3
Bone: trabecular tissue density0.10.20.70.10.3-0.3-0.5-0.3-0.3-0.2-0.2-0.4-0.8-0.1-0.2-0.80.80.3-0.20.8-0.3-0.4-0.1
Water consumed over 24 hours0.70.92.11.2-0.70.71.31.41.30.71.21.00.51.0-1.10.7-0.71.0-1.0-0.5-0.9-1.0-0.6
Number of responses in last shaping day0.60.62.2-0.71.0-1.0-0.6-0.8-0.8-0.5-0.4-0.7-1.1-0.30.1-1.51.50.20.01.2-0.5-0.0-0.1