Hub : Genes

Nudt3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Nudt3 0.07 0.03 1.5e-04 0.03 0.03 0.02 0.03 7.5e-05 6.5e-05 1.5e-03 8.0e-05
2 Brain gene expression Nudt3 0.24 0.08 5.6e-17 0.19 0.16 0.18 0.2 4.5e-17 2.4e-14 5.8e-17 3.5e-18
3 IC gene expression Nudt3 0.5 0.14 2.9e-11 0.16 0.29 0.18 0.27 2.8e-07 1.4e-12 4.5e-08 1.2e-11
4 NAcc gene expression Nudt3 0.19 0.07 7.8e-16 0.1 0.11 0.11 0.11 1.1e-14 9.7e-17 1.5e-16 1.7e-16
5 IL gene expression Nudt3 0.35 0.25 8.0e-03 0.04 0.02 0.1 0.13 4.9e-02 1.2e-01 2.8e-03 6.0e-04
6 PL gene expression Nudt3 0.21 0.07 5.3e-13 0.12 0.12 0.11 0.11 1.1e-12 3.1e-13 3.3e-12 1.9e-12
7 pVTA gene expression Nudt3 0.28 0.09 1.2e-15 0.13 0.23 0.23 0.23 8.6e-11 3.1e-18 1.6e-18 2.0e-18
8 Brain mRNA stability Nudt3 0.09 0.04 6.6e-07 0.07 0.06 0.07 0.08 1.6e-07 2.4e-06 2.0e-07 3.4e-08
9 Adipose gene expression Nudt3 0.07 0.05 1.5e-03 -0 0.01 0.01 0 6.2e-01 1.9e-02 1.0e-02 3.6e-01
10 Liver gene expression Nudt3 0.17 0.07 1.4e-07 0.02 0.05 0.05 0.04 6.0e-03 4.3e-06 2.6e-06 8.2e-06
11 BLA gene expression Nudt3 0.3 0.1 1.6e-07 0.1 0.1 0.11 0.1 3.6e-06 4.4e-06 2.2e-06 3.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.41.2-1.1-0.6-1.0-0.80.2-0.80.3-0.5-0.10.3-0.6
Area under the delay curve0.20.20.70.50.3-0.3-0.20.1-0.20.50.90.6-0.8-0.2
BMI with tail1.03.68.2-2.0-1.8-1.8-1.8-2.9-1.51.7-1.72.61.51.0
BMI without tail0.21.24.4-0.5-0.5-0.5-0.6-1.6-0.50.7-0.52.11.21.7
Body weight0.94.09.43.12.42.22.0-0.52.2-1.22.60.4-2.2-1.0
Weight adjusted by age0.82.25.82.41.61.61.1-0.31.4-0.42.40.1-2.00.4
Bone surface0.81.62.31.01.21.21.31.21.3-1.50.9-1.5-0.8-1.5
Bone volume0.10.21.00.10.40.20.30.60.2-0.40.3-0.6-0.2-1.0
Breakpoint value in progressive ratio session0.10.20.9-0.30.20.10.70.70.1-0.5-0.4-0.00.3-1.0
Number of licking bursts0.51.62.60.81.11.41.41.51.4-1.60.8-1.6-0.9-0.8
Context. condit. distance diff. score3.03.67.21.11.81.51.52.71.5-1.61.3-2.6-2.0-2.6
Locomotion velocity, session 10.50.62.00.70.70.50.31.40.2-0.61.1-0.8-0.80.1
Locomotion distance, session 10.50.71.5-1.1-1.1-0.7-0.9-0.2-0.70.2-1.2-0.61.00.6
Locomotion velocity, session 20.81.02.30.70.71.01.11.21.0-1.20.2-1.5-0.4-0.9
Locomotion distance, session 20.10.20.4-0.5-0.6-0.4-0.5-0.1-0.30.2-0.6-0.60.2-0.5
Locomotion velocity, session 30.20.20.7-0.4-0.5-0.2-0.10.2-0.3-0.0-0.8-0.20.80.8
Locomotion distance, session 30.40.51.1-1.0-0.7-0.7-0.80.5-0.80.3-0.9-0.30.50.5
Stereotopy head waving bouts, day 33.13.75.62.42.12.32.31.12.3-2.01.7-1.3-1.8-1.5
Stereotopy head waving duration, day 30.91.22.81.71.11.31.30.51.2-0.91.2-0.6-0.9-0.3
Locomotion velocity, session 70.60.61.4-0.9-0.3-1.1-1.20.2-1.01.00.1-0.2-0.4-1.0
Locomotion distance, session 70.70.81.9-1.1-0.7-1.3-1.40.7-1.41.3-0.2-0.10.1-0.2
Stereotopy head waving bouts, day 70.30.32.50.0-0.2-0.1-0.10.5-0.4-0.00.00.50.51.6
Stereotopy head waving duration, day 70.10.21.10.30.20.20.20.20.0-0.40.10.40.21.1
Locomotion velocity, session 85.86.98.92.72.72.62.73.02.6-2.52.2-2.8-2.5-2.6
Locomotion distance, session 81.52.16.80.50.91.00.91.81.1-1.20.3-2.6-1.3-2.5
Degree of sensitization distance1.11.22.51.21.11.01.10.71.1-0.51.3-0.8-1.1-1.6
Degree of sensitization stereotypy0.80.93.5-1.0-0.9-0.8-0.80.4-1.10.4-0.80.61.11.9
Conditioned locomotion0.80.93.00.90.81.01.0-0.01.1-0.60.6-0.9-0.8-1.7
Cocaine response after cond. corrected0.20.21.2-0.50.00.10.2-0.70.4-0.3-0.6-0.3-0.0-1.1
Cocaine response after cond. not corrected0.71.02.00.81.01.31.20.11.4-1.20.4-1.0-0.6-1.0
Cocaine response before conditioning2.63.16.72.61.92.21.91.42.0-1.62.1-1.2-1.30.2
Saline control response2.02.86.1-0.9-1.4-1.2-1.3-2.5-1.41.4-1.12.41.72.3
Bone: connectivity density0.20.31.9-0.30.3-0.1-0.10.50.1-0.30.2-0.7-0.4-1.4
Bone: cortical apparent density0.91.43.8-1.1-1.3-1.1-1.0-1.9-0.80.8-1.41.01.20.7
Bone: cortical area0.00.10.20.10.30.30.20.20.3-0.40.3-0.10.10.2
Bone: cortical porosity1.11.25.1-0.3-0.8-0.9-1.00.4-1.41.40.21.01.02.3
Bone: cortical porosity0.60.72.60.40.1-0.3-0.60.9-0.81.01.20.70.01.6
Bone: cortical thickness3.15.27.1-2.7-2.5-2.4-2.4-2.0-2.21.7-2.31.72.62.4
Bone: cortical thickness3.64.46.1-2.3-2.4-2.1-2.0-2.5-1.81.7-2.41.62.41.5
Bone: cortical tissue density0.61.03.2-0.8-1.1-0.9-0.8-1.8-0.60.6-1.20.81.00.6
Condit. Reinf. active minus inactive responses0.20.30.90.1-0.2-0.4-0.60.3-0.60.60.40.6-0.01.0
Condit. Reinf. active-inactive response ratio0.30.31.1-0.1-0.4-0.3-0.4-0.6-0.50.5-0.11.00.41.0
Condit. Reinf. active responses0.20.30.7-0.2-0.2-0.5-0.80.0-0.70.80.30.8-0.10.5
Condit. Reinf. inactive responses0.50.61.3-1.1-0.7-1.0-1.1-0.1-1.01.0-0.30.60.20.1
Incentive salience index mean0.40.51.70.50.70.40.21.30.2-0.21.0-0.5-0.9-0.4
Condit. Reinf. lever presses1.42.04.00.71.51.10.92.01.0-1.11.3-1.6-1.7-2.0
Condit. Reinf. active minus inactive responses0.20.31.11.00.30.60.60.30.5-0.00.7-0.2-0.20.5
Condit. Reinf. active-inactive response ratio0.40.61.71.30.81.00.90.50.9-0.41.0-0.2-0.70.2
Condit. Reinf. active responses0.10.10.40.6-0.10.30.30.20.20.10.3-0.40.10.3
Condit. Reinf. inactive responses0.10.20.5-0.3-0.7-0.4-0.3-0.4-0.30.3-0.7-0.20.70.1
Condit. Reinf. lever presses0.40.52.2-0.4-0.7-0.6-0.90.3-0.90.9-0.00.10.71.5
Condit. Reinf. lever reinforcers received0.10.10.40.5-0.10.30.20.30.10.10.3-0.40.20.6
Conditioned reinforcement - actives0.00.20.50.0-0.1-0.7-0.6-0.2-0.40.50.50.2-0.6-0.6
Conditioned reinforcement - inactives0.20.41.7-0.0-0.5-0.4-0.6-0.7-0.50.90.40.80.31.3
Conditioned locomotion0.40.62.40.70.6-0.1-0.30.2-0.10.61.60.4-1.5-0.3
Patch foraging indifference point 0 sec0.72.15.4-0.9-1.5-1.2-1.2-2.3-1.01.3-1.11.81.31.7
Patch foraging indifference point AUC1.02.43.61.81.61.91.71.71.8-1.91.0-1.7-0.8-0.2
Delay disc. indifference point, 0s delay0.30.30.90.50.60.20.10.50.3-0.10.7-0.1-1.0-0.9
Delay disc. indifference point, 16s delay0.91.22.2-0.8-1.2-1.3-1.3-1.1-1.21.5-0.21.30.71.0
Delay disc. indifference point, 2s delay0.70.82.91.31.10.50.40.60.4-0.11.7-0.1-1.5-0.4
Delay disc. indifference point, 24s delay0.91.43.9-0.2-0.9-1.1-1.3-1.1-1.21.70.62.00.01.5
Delay disc. indifference point, 4s delay0.80.81.71.31.20.80.80.70.8-0.70.9-0.2-1.3-0.8
Delay disc. indifference point, 8s delay0.20.30.80.30.2-0.4-0.40.1-0.50.70.90.9-0.60.1
Indifference point function ln k0.00.10.2-0.4-0.1-0.20.00.5-0.20.0-0.3-0.40.2-0.2
Indifference point function log k0.00.10.2-0.4-0.1-0.20.00.5-0.20.0-0.3-0.40.2-0.2
Patch foraging total patch changes 0 sec1.02.86.5-1.2-1.8-1.4-1.5-2.6-1.31.5-1.22.01.62.0
Patch foraging total patch changes 12 sec0.40.61.8-0.3-0.8-0.4-0.3-1.1-0.10.1-1.00.31.21.3
Patch foraging total patch changes 18 sec1.02.46.5-1.5-1.8-1.3-1.4-2.5-1.01.1-1.81.21.71.1
Patch foraging total patch changes 24 sec1.34.46.6-2.2-2.5-2.1-2.4-2.6-2.01.9-1.71.72.01.8
Patch foraging total patch changes 6 sec2.33.96.7-1.6-2.1-1.8-2.0-2.6-1.71.9-1.52.11.82.2
Patch foraging time to switch 0 sec0.82.97.2-1.8-1.8-1.7-1.5-2.7-1.41.8-1.71.81.4-0.1
Patch foraging water rate 0 sec0.00.20.60.60.40.30.10.00.5-0.20.8-0.2-0.60.4
Patch foraging water rate 12 sec0.31.32.3-1.5-1.5-1.3-1.3-0.8-1.20.8-1.40.21.30.7
Patch foraging water rate 18 sec0.10.20.80.20.4-0.1-0.3-0.0-0.10.30.90.5-0.60.3
Patch foraging water rate 24 sec0.10.10.7-0.4-0.4-0.4-0.20.0-0.1-0.1-0.9-0.30.3-0.2
Patch foraging water rate 6 sec0.20.20.7-0.6-0.7-0.3-0.3-0.3-0.2-0.0-0.8-0.40.70.1
Seeking ratio, delayed vs. immediate footshock0.40.61.30.40.30.71.00.50.7-1.2-0.9-0.90.6-0.7
Distance traveled before self-admin0.81.73.21.01.11.41.70.41.6-1.70.2-1.4-0.6-1.8
Distance traveled after self-admin1.22.04.41.51.41.72.10.41.7-1.80.3-1.4-0.5-1.5
Extensor digitorum longus weight0.93.84.82.12.02.02.01.72.0-2.01.6-2.2-1.9-1.9
Bone: elastic displacement1.62.04.8-0.9-1.3-1.5-1.7-0.8-1.71.6-0.41.41.12.2
Bone: elastic work0.70.91.8-0.6-0.8-1.1-1.2-0.7-1.21.1-0.01.20.61.3
Bone: endosteal estimation5.714.020.94.64.44.44.22.54.1-3.34.0-1.9-3.8-3.0
Bone: endosteal perimeter3.58.611.93.13.43.43.32.43.2-2.82.7-2.0-2.9-2.9
Epididymis fat weight7.839.660.2-6.9-7.0-6.5-6.4-7.8-5.75.7-6.26.16.14.3
Delta time in closed arm before/after self-admin1.21.22.3-0.9-0.8-1.2-1.1-1.3-1.21.5-0.41.50.80.7
Delta time in open arm before/after self-admin0.91.01.91.11.21.01.01.40.9-1.00.8-0.8-1.3-0.7
Diff in mean of infusions in LGA sessions0.20.41.2-1.1-0.6-0.5-0.30.1-0.40.2-0.8-0.00.5-1.0
Delay discount exponential model param0.20.20.7-0.5-0.20.30.3-0.10.3-0.5-0.9-0.60.80.1
Extinction: sum of active levers before priming0.00.10.2-0.5-0.3-0.10.1-0.10.0-0.3-0.5-0.20.3-0.1
Active lever presses in extinction session 62.02.04.4-1.1-1.0-1.5-1.7-0.9-1.72.00.12.10.71.6
Bone: final force0.50.83.9-0.4-0.7-0.6-0.5-2.0-0.30.7-0.61.50.60.2
Bone: final moment0.30.52.1-0.2-0.4-0.4-0.4-1.4-0.30.6-0.11.50.20.2
Food consumed during 24 hour testing period0.30.61.50.70.80.90.9-0.50.9-0.50.4-0.1-0.6-1.2
Glucose4.47.011.12.93.12.72.33.02.4-1.93.3-1.8-3.2-1.5
Heart weight0.60.95.10.7-0.1-0.1-0.7-0.9-0.31.01.10.9-0.12.3
Delay discount hyperbolic model param0.20.20.8-0.6-0.30.20.2-0.20.2-0.4-0.9-0.40.7-0.0
Intermittent access intake day 1-15 change0.00.20.70.00.20.20.60.20.3-0.6-0.5-0.20.2-0.8
Intermittent access intake escalation0.00.10.3-0.2-0.3-0.30.1-0.2-0.3-0.0-0.60.40.5-0.3
Intermittent access intake escalation 20.61.11.71.11.20.91.11.30.7-1.01.0-0.6-1.1-1.0
Intermitt. access day 1 inactive lever presses0.11.53.40.20.81.21.50.91.4-1.8-1.1-1.90.6-1.0
Intermitt. access day 15 inactive lever presses0.10.71.41.00.91.11.20.21.1-1.00.3-0.7-0.4-0.5
Intermitt. access escalation Index0.41.13.4-0.80.10.20.50.90.4-1.2-1.6-1.60.5-1.9
Intermittent access day 1 total infusions0.31.02.0-0.2-0.5-1.2-1.4-0.1-1.11.41.30.9-0.61.0
Intermittent access day 15 total infusions0.20.40.7-0.3-0.6-0.9-0.8-0.4-0.80.80.40.80.10.7
Intermittent access terminal intake (last 3 days)0.40.61.2-0.2-0.7-0.9-0.9-0.7-0.91.00.51.00.11.1
Intermittent access total infusions0.50.61.2-0.0-0.4-0.8-0.9-0.3-0.81.01.00.9-0.31.1
Intermittent access day 1 locomotion0.10.10.50.30.1-0.2-0.3-0.2-0.00.20.6-0.1-0.7-0.5
Intermittent access day 15 total locomotion0.20.61.61.20.90.50.5-0.20.5-0.11.30.4-1.2-0.8
Intermittent access total locomotion0.50.62.11.10.70.40.2-0.10.4-0.11.40.1-1.4-0.4
Intermittent access standard deviation0.10.52.70.0-0.5-0.10.1-1.60.10.3-0.60.90.90.5
Left kidney weight0.10.93.01.70.71.11.1-0.91.2-0.61.00.2-0.8-0.3
Right kidney weight0.42.66.02.41.71.81.9-0.31.9-1.21.7-0.1-1.7-1.5
Cocaine induced anxiety0.92.44.51.11.61.71.71.01.7-2.1-0.0-2.0-0.9-1.7
Post-drug Anxiety0.60.71.60.60.81.11.0-0.01.2-1.2-0.1-0.9-0.5-0.8
Baseline Anxiety1.62.74.7-1.6-1.8-1.7-1.7-2.2-1.51.9-0.82.11.10.9
Tail length2.915.728.95.44.74.84.43.34.2-3.84.1-2.4-3.4-1.5
Length with tail5.223.345.16.75.65.55.13.25.1-4.15.5-2.8-4.9-2.7
Length without tail1.68.316.64.13.33.02.70.43.2-1.83.6-1.1-3.7-2.5
Times rat made contact with spout3.13.65.1-2.0-2.0-2.2-2.1-1.2-2.31.8-1.51.51.92.0
Lifetime Intake0.50.61.10.1-0.3-0.7-0.9-0.3-0.71.11.11.0-0.31.1
Liver weight, left5.49.313.33.43.73.53.32.13.4-3.12.8-2.1-3.1-2.8
Liver weight, right10.418.125.15.04.84.94.73.44.6-4.23.8-3.3-4.2-3.4
Locomotor activity1.01.63.81.21.21.71.80.81.5-2.00.3-1.2-0.4-0.2
Locomotor testing distance0.10.31.0-0.20.10.50.7-0.40.6-1.0-0.9-0.50.4-0.5
Locomotor testing rearing0.31.02.80.60.81.01.3-0.11.3-1.3-0.2-0.8-0.5-1.7
Locomotion in novel chamber0.00.10.40.10.1-0.20.10.7-0.0-0.20.1-0.1-0.2-0.1
Locomotion in novel chamber post-restriction0.10.31.1-0.3-0.3-0.5-0.5-1.0-0.40.6-0.31.00.3-0.3
Fecal boli incidents, locomotor time 10.10.30.6-0.2-0.0-0.6-0.5-0.2-0.50.60.70.6-0.8-0.4
Change in fecal boli incidents, locomotor task0.20.30.70.50.50.80.7-0.40.8-0.4-0.2-0.20.10.0
Time >=10cm from walls, locomotor time 11.51.93.41.11.81.71.80.41.8-1.60.2-0.7-1.1-1.4
Bouts of movement, locomotor time 10.81.01.90.40.90.91.21.30.8-1.40.1-1.3-0.3-1.3
Total resting periods, locomotor time 11.21.42.20.81.31.21.41.41.1-1.50.5-1.4-0.7-1.4
Rest time, locomotor task time 10.50.81.80.91.00.50.51.30.6-0.70.9-1.1-1.1-0.8
Distance moved, locomotor task time 10.10.31.6-0.2-0.4-0.1-0.1-1.3-0.10.4-0.51.00.70.6
Vertical activity count, locomotor time 10.10.42.30.1-0.10.10.3-1.50.10.3-0.51.30.60.3
Time >=10cm from walls, locomotor time 20.20.61.60.80.90.50.3-0.70.50.20.81.3-1.3-0.2
Bouts of movement, locomotor time 21.03.35.41.92.02.12.22.11.7-2.30.8-1.7-1.1-1.3
Total resting periods, locomotor time 21.04.16.72.12.22.32.42.61.9-2.60.9-2.1-1.2-1.3
Rest time, locomotor task time 22.54.36.71.62.12.12.22.22.2-2.50.6-2.6-1.8-2.2
Distance moved, locomotor task time 22.33.17.6-0.9-1.4-1.5-1.8-2.7-1.52.40.22.80.71.5
Vertical activity count, locomotor time 20.71.64.7-0.3-0.8-1.1-1.2-2.2-1.01.80.42.10.20.8
Light reinforcement 10.20.92.6-0.6-0.20.10.5-1.60.6-0.9-1.6-0.30.8-1.6
Light reinforcement 20.40.94.20.70.80.71.0-0.41.1-0.9-0.0-0.5-0.5-2.1
Bone: marrow area5.713.920.94.64.44.34.22.44.1-3.34.0-1.8-3.8-3.0
Bone: maximum diameter3.16.38.52.62.92.72.62.52.5-2.52.5-2.1-2.3-2.1
Bone: maximum force0.10.10.50.30.10.10.1-0.70.3-0.00.30.6-0.2-0.2
Bone: maximum moment0.10.20.80.60.50.20.2-0.20.3-0.00.90.6-0.6-0.1
Mean time between licks in bursts1.16.813.42.62.22.82.82.82.7-2.61.5-3.7-2.0-2.4
Mean num. licks in bursts1.64.25.8-1.7-2.1-2.4-2.3-1.9-2.42.2-1.42.11.81.9
Cd content in liver1.01.12.6-0.6-0.7-1.3-1.4-1.6-0.91.6-0.11.3-0.2-0.4
Co content in liver1.92.36.3-1.2-1.3-1.5-1.6-2.5-1.21.8-0.52.20.70.8
Cu content in liver3.64.36.7-2.6-2.5-2.3-2.2-1.3-2.21.6-2.11.42.21.8
Fe content in liver0.20.20.6-0.1-0.7-0.4-0.3-0.7-0.30.5-0.50.40.3-0.2
K content in liver0.20.21.60.1-0.10.20.00.80.1-0.20.1-1.3-0.0-0.4
Mg content in liver2.22.47.31.21.31.71.51.61.6-1.60.7-2.7-0.9-1.5
Mn content in liver7.58.412.13.02.73.13.12.43.2-2.72.0-3.5-2.7-3.1
Na content in liver0.60.72.2-1.0-1.1-0.7-0.5-0.2-0.70.3-1.2-0.21.50.8
Rb content in liver0.30.31.10.20.50.2-0.10.20.2-0.20.8-0.2-1.0-1.0
Se content in liver4.25.07.82.52.02.62.42.72.3-2.41.6-2.8-1.6-1.0
Sr content in liver0.40.30.90.20.2-0.3-0.4-0.5-0.30.70.90.9-0.7-0.1
Zn content in liver0.70.81.51.20.80.90.70.71.0-0.60.9-1.1-1.0-0.9
Bone: minimum diameter2.44.77.02.42.62.52.31.62.4-1.92.2-1.4-2.2-2.0
Time in familiar zone, hab. session 12.32.54.4-1.8-1.7-2.0-1.9-0.5-2.11.8-1.21.21.21.2
Time in novel zone, hab. session 11.31.42.51.41.31.51.40.31.6-1.41.0-0.8-1.0-0.8
Total zone transitions, hab. session 10.50.71.8-1.2-1.0-0.6-0.7-0.2-0.5-0.1-1.3-0.51.20.9
Total locomotion distance, hab. session 10.50.72.1-1.0-0.9-0.3-0.4-0.0-0.3-0.2-1.4-1.01.20.5
Locomotion velocity, hab. session 10.50.72.1-0.9-1.0-0.4-0.4-0.1-0.3-0.0-1.4-1.01.30.7
Time in familiar zone, hab. session 20.50.61.7-0.1-0.30.50.80.10.6-1.1-1.2-1.30.7-0.5
Time in novel zone, hab. session 20.70.82.60.30.5-0.5-0.9-0.3-0.71.11.41.6-0.80.5
Total zone transitions, hab. session 20.40.51.5-0.5-0.40.30.4-0.20.5-1.0-1.2-1.20.6-0.5
Total locomotion distance, hab. session 20.70.93.5-1.1-0.70.00.20.00.3-0.9-1.9-1.71.0-0.5
Locomotion velocity, hab. session 20.71.03.5-1.0-0.70.10.20.20.3-0.9-1.8-1.91.0-0.5
Novel to familiar place preference ratio0.81.01.8-1.0-0.9-1.2-1.2-0.6-1.21.1-0.31.30.71.1
Novelty place preference0.50.71.3-0.7-0.7-0.9-1.0-0.5-0.90.9-0.21.10.51.0
Time in novel zone, NPP test0.40.41.1-0.4-0.5-0.8-0.8-0.3-0.80.70.01.00.30.9
Total zone transitions, NPP test0.20.31.4-0.7-0.5-0.1-0.20.4-0.1-0.3-0.9-1.20.5-0.2
Total locomotion distance, NPP test0.50.61.5-1.2-0.9-0.9-1.1-0.4-0.80.7-1.1-0.20.5-0.2
Locomotion velocity, NPP test0.81.12.8-1.7-1.3-1.1-1.2-0.5-1.00.7-1.6-0.31.00.2
Intraocular pressure0.10.11.20.00.0-0.1-0.1-0.30.0-0.10.1-0.2-0.5-1.1
Delta distance traveled before/after self-admin0.20.20.70.70.30.20.20.10.00.10.70.6-0.10.8
Delta ambulatory time before/after self-admin0.20.30.80.90.60.70.60.30.5-0.50.7-0.0-0.40.2
Parametrial fat weight0.20.52.70.00.20.20.6-1.30.5-0.5-0.30.5-0.2-1.7
Pavlov. Cond. lever latency1.31.78.2-0.9-1.2-0.8-0.6-2.9-0.50.7-1.61.41.40.2
Pavlov. Cond. magazine entry latency2.33.09.21.61.81.71.53.01.3-1.61.9-1.8-1.4-0.2
Pavlov. Cond. change in total contacts1.01.13.21.01.11.00.71.80.6-0.71.6-0.5-1.00.4
Pavlov. Cond. index score2.12.69.81.41.71.41.13.11.0-1.22.0-1.6-1.6-0.3
Pavlov. Cond. latency score2.02.59.71.31.61.31.13.10.9-1.21.9-1.7-1.5-0.3
Pavlov. Cond. lever contacts1.21.55.60.81.30.80.52.40.6-0.61.6-1.1-1.5-0.5
Pavlov. Cond. magazine entry number1.51.96.3-1.2-1.4-1.4-1.1-2.5-1.11.3-1.51.61.1-0.1
Pavlov. Cond. intertrial magazine entries2.83.46.5-1.6-1.9-1.9-2.1-2.6-1.82.2-1.31.81.41.1
Pavlov. Cond. lever-magazine prob. diff.1.82.29.21.21.51.20.93.00.8-1.01.8-1.4-1.5-0.1
Pavlov. Cond. response bias2.43.08.81.61.81.61.33.01.3-1.51.9-1.9-1.7-0.4
Pavlov. Cond. lever latency0.91.33.10.81.21.21.40.41.4-1.30.5-0.7-1.0-1.8
Pavlov. Cond. magazine entry latency0.50.72.11.01.10.60.51.10.4-0.21.50.0-1.2-0.6
Pavlov. Cond. change in total contacts0.30.82.4-0.4-0.8-0.8-0.9-0.1-1.11.0-0.10.90.91.5
Pavlov. Cond. index score0.10.20.50.30.0-0.2-0.40.6-0.50.60.70.4-0.20.7
Pavlov. Cond. latency score0.10.20.40.20.0-0.2-0.40.5-0.50.50.50.4-0.10.6
Pavlov. Cond. lever contacts1.01.43.3-0.9-1.3-1.2-1.5-0.5-1.41.4-0.50.81.11.8
Pavlov. Cond. magazine entry number0.10.10.5-0.2-0.30.10.2-0.40.2-0.4-0.7-0.60.50.1
Pavlov. Cond. intertrial magazine entries1.63.67.81.41.32.12.41.92.2-2.50.2-2.8-0.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.2-0.1-0.3-0.50.5-0.60.70.50.4-0.10.7
Pavlov. Cond. response bias0.30.41.1-0.1-0.4-0.5-0.90.3-0.80.90.40.30.31.1
Time in closed arm before self-admin0.10.10.50.30.20.20.10.20.2-0.10.5-0.1-0.7-0.3
Time in closed arm after self-admin1.51.63.2-1.1-1.2-1.5-1.7-1.1-1.61.8-0.21.40.61.1
Time in open arm before self-admin0.20.21.1-0.1-0.5-0.2-0.20.0-0.40.30.10.20.61.0
Time in open arm after self-admin0.91.01.91.21.01.11.21.41.0-1.10.8-1.0-0.9-0.3
Bone: periosteal estimation2.55.98.62.92.92.92.81.62.7-2.42.6-1.3-2.2-1.8
Bone: periosteal perimeter1.02.03.21.61.81.71.61.21.6-1.31.5-0.7-1.2-0.9
Bone: post-yield work2.64.56.72.22.62.12.01.92.1-1.72.2-1.4-2.6-2.4
Progressive ratio test 1 active lever presses0.30.61.5-0.1-0.3-0.7-0.9-0.7-0.71.20.81.2-0.20.9
Progressive ratio test 1 breakpoint0.30.61.4-0.1-0.3-0.6-0.9-0.7-0.61.20.81.1-0.21.0
Progressive ratio test 1 inactive lever presses0.41.12.9-1.0-1.1-1.1-0.9-1.7-0.81.0-0.81.00.90.2
Progressive ratio test 2 active lever presses0.20.30.7-0.4-0.3-0.7-0.70.1-0.70.80.30.70.00.4
Progressive ratio test 2 breakpoint0.30.30.8-0.4-0.4-0.8-0.80.1-0.70.90.30.80.00.4
Progressive ratio test 2 inactive lever presses0.10.41.60.80.90.50.20.70.30.11.3-0.1-1.0-0.0
Incentive Sensitization - Responses0.10.21.1-0.20.1-0.10.11.0-0.0-0.4-0.3-0.70.1-0.6
Incentive Sensitization - Breakpoint0.10.21.0-0.30.1-0.20.11.0-0.1-0.4-0.4-0.60.1-0.7
Sum of active levers in priming session hrs 5-60.10.10.4-0.1-0.1-0.2-0.20.4-0.30.30.20.3-0.00.6
Progressive ratio0.10.41.90.3-0.30.20.5-1.40.30.1-0.80.70.80.6
Food seeking constrained by brief footshock1.21.54.0-0.7-0.8-1.2-1.3-0.5-1.41.40.32.00.41.9
Seeking ratio, punishment vs. effort0.30.61.2-0.8-0.4-0.9-1.10.7-1.10.70.40.50.10.9
Retroperitoneal fat weight0.00.10.40.10.00.20.1-0.60.2-0.00.00.3-0.3-0.6
Reaction time number correct0.51.82.5-1.5-1.6-1.4-1.1-1.4-1.31.3-1.61.51.30.8
Reaction time mean minus median1.48.811.63.23.43.12.93.42.7-2.73.1-2.5-3.1-2.5
Reaction time mean minus median AUC0.96.110.12.82.92.22.03.01.9-1.53.2-1.6-3.2-2.2
Reaction time num false alarms0.71.23.50.80.81.21.41.11.3-1.5-0.1-1.90.1-0.7
Reaction time num false alarms AUC0.61.54.30.90.81.41.51.21.4-1.6-0.0-2.10.2-0.3
Reaction time trials correct on left0.51.82.5-1.5-1.6-1.4-1.1-1.4-1.31.3-1.61.51.30.8
Reaction time trials on left0.51.62.2-1.4-1.5-1.3-1.1-1.3-1.21.3-1.51.51.20.7
Reaction time mean2.65.79.82.52.92.32.02.42.0-1.73.0-1.4-3.1-2.3
Reaction time mean AUC2.45.710.32.52.92.22.02.51.9-1.63.2-1.1-3.2-2.4
Median of all reaction times1.92.96.21.72.21.51.31.51.4-0.92.4-0.6-2.5-1.8
Reaction time omissions3.25.36.81.92.62.42.42.32.3-2.41.7-2.2-2.2-2.6
Reaction time false alarm rate2.02.86.71.51.51.91.81.81.8-2.00.8-2.6-0.5-0.5
Reaction time premature initiation rate0.00.10.4-0.1-0.2-0.3-0.1-0.6-0.0-0.1-0.10.20.10.1
Reaction time premature initiations0.30.92.1-0.9-1.0-1.0-0.8-1.5-0.80.8-1.01.10.80.5
Std. dev. reaction times2.99.813.83.53.73.23.03.52.8-2.63.7-2.3-3.4-2.3
Reaction time trials completed0.51.62.2-1.4-1.5-1.3-1.1-1.3-1.21.3-1.51.51.20.7
Reaction time trials AUC0.51.62.3-1.4-1.5-1.3-1.1-1.4-1.21.3-1.51.41.20.6
Run reversals in cocaine runway, females1.71.93.7-0.8-1.1-1.4-1.7-1.4-1.61.90.11.80.51.5
Run reversals in cocaine runway, males3.43.76.12.02.32.01.72.51.7-1.91.8-1.9-2.0-1.2
Latency to leave start box in cocaine runway0.10.20.5-0.6-0.4-0.1-0.3-0.5-0.10.3-0.30.20.40.7
Latency to leave start box in cocaine runway, F0.10.10.7-0.5-0.6-0.2-0.3-0.8-0.20.2-0.20.00.10.1
Latency to leave start box in cocaine runway, M0.20.21.1-0.20.10.20.00.10.10.2-0.20.40.61.0
Std. dev. time between licks in bursts3.15.910.32.42.22.62.62.52.6-2.51.5-3.2-2.0-2.3
Total sessions with >9 infusions0.20.20.90.3-0.1-0.3-0.4-0.1-0.40.60.70.6-0.11.0
Short access day 1 total inactive lever presses0.81.54.51.61.61.11.01.10.8-0.62.1-0.2-1.6-0.2
Short access day 10 total inactive lever presses0.31.94.2-0.30.41.11.50.81.2-2.1-2.0-2.01.3-1.2
Short access day 1 total infusions0.20.31.40.40.2-0.1-0.2-0.0-0.20.51.20.5-0.41.0
Short access day 10 total infusions0.10.10.2-0.1-0.3-0.5-0.4-0.2-0.40.40.10.40.10.3
Short access total infusions0.40.51.0-0.0-0.3-0.7-0.8-0.4-0.71.00.91.0-0.20.9
Short access day 1 locomotion0.10.20.5-0.20.10.30.30.40.3-0.5-0.6-0.70.6-0.1
Short access day 10 total locomotion0.62.44.51.61.61.91.90.52.0-2.10.2-1.7-0.6-1.2
Short access total locomotion0.30.50.90.70.80.90.80.00.9-0.80.2-0.8-0.4-0.8
One hour access (0.3 mA shock)0.30.31.4-0.30.0-0.10.11.10.0-0.5-0.3-1.2-0.0-0.8
Compulsive drug intake1.62.36.40.31.21.31.61.41.4-1.9-0.5-2.3-0.4-2.5
One hour access (shock baseline)0.20.61.50.1-0.2-0.6-0.90.3-0.80.91.10.8-0.51.2
Social response proportion0.20.20.60.80.50.70.6-0.40.7-0.40.3-0.5-0.20.1
Social responses0.50.61.20.80.51.01.10.11.1-1.1-0.3-1.00.1-0.4
Social time6.19.516.92.22.83.33.63.03.4-4.10.7-4.1-1.7-3.2
Soleus weight6.418.826.25.14.94.84.53.34.6-4.04.3-4.0-4.1-3.6
Bone: stiffness0.10.20.8-0.2-0.3-0.10.1-0.90.2-0.2-0.50.00.4-0.5
Tibialis anterior weight0.10.51.3-0.7-1.0-0.7-0.4-1.0-0.40.1-1.2-0.21.00.1
Time to tail flick, vehicle, before self-admin1.92.49.20.20.61.21.60.61.5-1.9-1.1-2.2-0.2-3.0
Time to tail flick, vehicle, after self-admin0.30.71.20.81.00.90.81.10.8-0.80.7-0.6-0.9-0.8
Time to tail flick, test, before self-admin0.30.41.6-0.6-0.7-0.20.00.2-0.2-0.4-1.3-0.70.9-0.0
Time to tail flick, test, after self-admin0.40.43.20.20.30.40.41.8-0.0-0.50.2-0.7-0.3-0.6
Delta time to tail flick, vehicle, before/after SA2.12.36.0-0.8-0.8-1.5-1.8-0.0-1.81.80.82.20.22.4
Delta time to tail flick, test, before/after SA0.20.20.4-0.6-0.1-0.4-0.50.3-0.60.6-0.20.60.2-0.1
Tibia length3.910.915.53.73.93.93.92.53.8-3.52.7-2.1-2.9-2.8
Ambulatory time before self-admin0.20.51.10.40.50.71.00.40.8-1.0-0.1-0.9-0.1-0.9
Ambulatory time after self-admin0.81.22.81.21.01.41.70.41.3-1.50.4-1.0-0.5-0.9
Bone: tissue strength0.30.31.30.10.2-0.4-0.4-0.1-0.30.40.91.1-1.0-0.1
Total heroin consumption0.60.71.70.30.50.91.30.90.9-1.3-0.5-1.00.3-0.8
Bone: trabecular number0.50.92.2-1.5-1.1-1.3-1.2-0.1-1.20.6-0.9-0.00.7-0.3
Bone: trabecular spacing0.50.72.01.40.91.01.0-0.20.9-0.31.00.6-0.60.3
Bone: trabecular thickness0.20.21.4-0.5-0.0-0.5-0.40.3-0.40.20.0-0.3-0.3-1.2
Bone: trabecular tissue density0.30.61.71.10.70.70.61.10.3-0.21.30.1-0.50.8
Water consumed over 24 hours0.10.20.60.20.70.50.30.40.5-0.70.6-0.2-0.5-0.3
Number of responses in last shaping day0.60.83.91.00.50.40.0-0.00.10.51.60.4-0.52.0