Nudt15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr15_55121464_55123103 0.41 0.15 0.0e+00 0.17 0.17 0.17 0.17 4.3e-18 3.0e-18 5.6e-18 6.8e-18
2 PL intron excision ratio chr15_55121464_55122799 0.45 0.16 5.6e-17 0.16 0.16 0.17 0.16 5.9e-17 1.7e-17 5.7e-18 1.1e-16
3 NAcc intron excision ratio chr15_55121464_55123103 0.1 0.05 4.0e-13 0.08 0.08 0.09 0.09 1.1e-12 1.6e-12 5.7e-13 1.9e-13
4 IC intron excision ratio chr15_55121464_55122799 0.12 0.06 6.9e-05 0.1 0.09 0.09 0.06 4.8e-05 2.0e-04 9.0e-05 2.5e-03
5 IC intron excision ratio chr15_55121464_55123103 0.12 0.06 5.9e-05 0.1 0.09 0.09 0.06 4.2e-05 1.8e-04 9.4e-05 2.5e-03
6 Brain intron excision ratio chr15_55121464_55123103 0.15 0.07 5.7e-10 0.1 0.11 0.11 0.11 6.8e-10 1.2e-10 1.1e-10 1.8e-10
7 BLA intron excision ratio chr15_55121464_55123103 0.08 0.06 3.5e-03 0.02 0.04 0.02 0.02 4.2e-02 5.4e-03 4.6e-02 3.2e-02
8 BLA intron excision ratio chr15_55121464_55122799 0.08 0.06 3.4e-03 0.02 0.04 0.02 0.02 4.1e-02 5.2e-03 4.5e-02 3.2e-02
9 pVTA gene expression Nudt15 0.38 0.12 0.0e+00 0.28 0.32 0.32 0.28 7.7e-23 4.1e-26 5.0e-26 2.2e-22
10 Adipose intron excision ratio chr15_55121464_55123103 0.02 0.02 8.9e-03 0.02 0.01 0.01 0.01 4.5e-03 2.1e-02 1.1e-02 1.5e-02
11 pVTA intron excision ratio chr15_55121464_55122799 0.26 0.13 5.1e-13 0.18 0.17 0.18 0.18 2.3e-14 1.5e-13 2.3e-14 2.6e-14
12 pVTA intron excision ratio chr15_55121464_55123103 0.24 0.12 1.6e-12 0.17 0.16 0.17 0.17 5.7e-14 3.1e-13 7.6e-14 6.6e-14
13 Adipose gene expression Nudt15 0.07 0.04 3.5e-07 0.04 0.05 0.05 0.05 4.0e-05 2.0e-06 2.0e-06 1.8e-06
14 Liver intron excision ratio chr15_55121464_55123103 0.08 0.04 2.7e-08 0.07 0.06 0.06 0.06 5.7e-08 1.9e-07 2.8e-07 1.5e-07
15 LHb gene expression Nudt15 0.49 0.15 1.1e-09 0.3 0.36 0.38 0.38 9.8e-08 2.1e-09 7.2e-10 5.2e-10
16 Brain mRNA stability Nudt15 0.09 0.04 8.1e-09 0.07 0.09 0.09 0.08 5.9e-07 8.1e-09 2.6e-08 8.2e-08
17 Brain gene expression Nudt15 0.51 0.13 0.0e+00 0.37 0.38 0.38 0.39 8.5e-36 1.5e-37 5.0e-37 1.7e-38
18 IC gene expression Nudt15 0.4 0.13 1.5e-15 0.35 0.34 0.33 0.33 1.8e-15 1.0e-14 2.2e-14 1.7e-14
19 PL gene expression Nudt15 0.37 0.09 0.0e+00 0.37 0.38 0.38 0.38 5.6e-42 3.7e-44 2.0e-43 7.6e-44
20 BLA gene expression Nudt15 0.47 0.14 0.0e+00 0.31 0.3 0.3 0.32 8.3e-17 1.5e-16 3.4e-16 1.5e-17
21 NAcc gene expression Nudt15 0.35 0.09 0.0e+00 0.31 0.44 0.44 0.44 2.7e-48 1.3e-73 1.4e-73 7.0e-74
22 OFC gene expression Nudt15 0.25 0.12 1.1e-04 0.21 0.15 0.18 0.19 8.7e-06 2.6e-04 5.9e-05 2.3e-05
23 IL gene expression Nudt15 0.36 0.14 6.9e-07 0.24 0.23 0.22 0.24 1.3e-06 2.5e-06 6.6e-06 2.2e-06
24 Liver gene expression Nudt15 0.06 0.04 3.7e-06 0.05 0.05 0.04 0.04 2.4e-06 4.5e-06 2.6e-05 9.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.20.41.9-0.91.1-0.60.6-0.6-0.5-1.41.40.5-0.40.6-0.60.3-0.30.4-0.20.30.20.30.1-0.10.2-0.20.3
Area under the delay curve0.50.62.2-1.21.5-1.10.6-0.6-0.9-1.51.50.5-0.70.6-0.60.7-0.70.2-0.10.1-0.1-0.3-0.2-0.9-0.2-0.2-0.1
BMI with tail0.00.10.60.8-0.70.7-0.20.20.60.2-0.2-0.30.00.0-0.0-0.20.2-0.1-0.3-0.0-0.10.30.20.70.60.20.1
BMI without tail0.20.52.01.1-1.01.1-0.40.40.80.9-0.9-0.30.6-0.50.5-0.50.50.1-0.20.30.40.80.81.40.70.90.6
Body weight0.31.43.6-1.11.1-1.21.2-1.2-1.4-0.90.91.5-0.81.9-1.91.8-1.81.01.30.70.60.80.80.40.71.30.5
Weight adjusted by age1.11.74.71.1-0.80.2-0.70.70.70.6-0.6-1.70.2-1.31.3-1.31.3-1.2-1.4-1.8-1.5-2.2-2.0-1.8-1.0-2.1-0.9
Bone surface0.40.63.2-1.31.7-1.00.4-0.4-0.7-1.81.80.5-0.70.7-0.70.3-0.30.0-0.30.1-0.20.0-0.2-0.7-0.0-0.5-0.5
Bone volume0.40.73.6-1.41.7-1.00.6-0.6-0.8-1.91.90.6-0.40.7-0.70.5-0.50.3-0.40.10.00.2-0.1-0.5-0.2-0.3-0.2
Breakpoint value in progressive ratio session0.20.32.0-0.30.50.1-0.50.50.10.2-0.2-0.11.4-0.10.1-0.00.0-0.4-0.4-0.2-0.1-0.1-0.1-0.0-1.40.0-1.3
Number of licking bursts0.61.12.8-0.70.5-0.20.4-0.4-0.8-0.0-0.01.2-0.10.9-0.91.3-1.31.01.21.41.31.51.61.30.91.70.9
Context. condit. distance diff. score1.92.210.11.3-1.71.9-0.80.81.11.5-1.50.41.0-0.10.10.1-0.10.80.61.41.72.32.03.21.62.51.7
Locomotion velocity, session 11.11.22.80.4-0.3-0.0-0.50.50.6-0.00.0-1.20.6-0.90.9-1.21.2-0.9-1.4-1.6-1.2-1.7-1.6-1.5-1.5-1.6-1.3
Locomotion distance, session 10.50.72.3-1.31.5-1.30.8-0.8-1.0-1.41.40.4-0.60.5-0.50.5-0.50.2-0.1-0.2-0.3-0.6-0.5-1.3-0.5-0.5-0.5
Locomotion velocity, session 20.30.41.6-0.80.9-0.90.6-0.6-0.5-0.70.7-0.1-0.5-0.30.30.1-0.10.3-0.2-0.2-0.1-0.7-0.6-1.3-0.4-1.0-0.4
Locomotion distance, session 21.52.17.0-2.32.6-2.31.5-1.5-1.8-2.42.40.7-0.90.8-0.81.0-1.00.4-0.3-0.2-0.5-1.0-0.9-2.2-0.9-1.0-0.7
Locomotion velocity, session 30.30.30.70.7-0.70.7-0.40.40.80.8-0.8-0.40.5-0.60.6-0.60.60.2-0.20.10.60.40.20.80.20.10.3
Locomotion distance, session 30.50.52.30.3-0.20.6-0.20.20.40.6-0.60.30.30.0-0.00.1-0.10.70.40.81.21.31.11.50.81.20.7
Stereotopy head waving bouts, day 30.80.92.01.0-1.10.5-0.60.60.71.0-1.0-1.30.8-1.31.3-1.01.0-0.8-0.8-1.1-0.8-1.3-0.9-0.9-0.7-1.4-0.5
Stereotopy head waving duration, day 30.70.82.20.4-0.60.2-0.40.40.30.2-0.2-1.10.8-0.80.8-0.60.6-0.9-1.1-1.2-1.1-1.5-1.3-1.3-1.1-1.4-0.7
Locomotion velocity, session 73.94.316.40.9-1.11.40.4-0.41.11.7-1.70.90.3-0.00.0-0.30.32.31.52.83.23.43.14.13.12.53.3
Locomotion distance, session 72.22.812.31.1-1.11.5-0.10.11.41.5-1.50.50.6-0.10.1-0.80.81.50.92.12.42.82.33.52.31.92.4
Stereotopy head waving bouts, day 70.30.31.3-0.80.5-1.00.8-0.8-1.0-0.60.60.1-0.50.0-0.00.5-0.50.40.1-0.20.0-0.7-0.3-1.1-0.0-0.40.1
Stereotopy head waving duration, day 70.20.31.6-0.2-0.1-0.50.2-0.2-0.5-0.00.0-0.3-0.1-0.40.40.2-0.2-0.3-0.2-0.6-0.5-1.1-0.6-1.3-0.6-0.6-0.3
Locomotion velocity, session 80.30.41.1-0.3-0.10.10.3-0.3-0.4-0.00.00.60.20.1-0.10.7-0.70.80.40.81.00.91.10.90.71.00.8
Locomotion distance, session 81.11.52.7-1.31.1-0.71.1-1.1-1.0-1.11.11.4-0.61.1-1.11.4-1.41.60.81.41.61.61.41.01.11.61.3
Degree of sensitization distance0.90.93.50.9-0.81.0-0.10.11.11.1-1.1-0.10.5-0.50.5-1.11.10.70.31.21.11.41.11.91.30.61.3
Degree of sensitization stereotypy0.30.31.0-0.90.7-0.90.6-0.6-1.0-0.50.50.5-0.50.4-0.40.8-0.80.50.50.20.3-0.10.1-0.6-0.10.20.0
Conditioned locomotion0.60.71.81.3-1.31.3-1.21.21.11.2-1.2-0.60.7-0.60.6-0.50.5-0.6-0.2-0.3-0.20.20.00.90.30.1-0.4
Cocaine response after cond. corrected2.53.05.62.4-2.32.1-2.22.22.32.2-2.1-1.82.0-1.81.8-2.22.2-1.5-1.3-1.0-0.8-0.6-0.80.6-0.8-1.0-0.9
Cocaine response after cond. not corrected0.81.02.11.4-1.21.1-1.21.21.41.2-1.2-1.11.1-1.21.2-1.51.5-0.6-0.8-0.5-0.1-0.2-0.40.5-0.3-0.5-0.2
Cocaine response before conditioning3.54.27.6-2.72.8-2.62.5-2.5-2.5-2.42.42.2-2.32.0-2.02.2-2.22.21.61.61.71.11.2-0.31.31.31.4
Saline control response1.52.04.3-1.92.0-1.71.4-1.4-1.8-1.21.21.8-0.82.0-2.02.1-2.11.01.51.00.80.80.80.00.31.30.2
Bone: connectivity density0.30.51.3-0.70.7-0.50.6-0.6-0.5-0.60.60.9-0.91.1-1.10.6-0.60.50.90.80.40.80.50.50.80.50.3
Bone: cortical apparent density1.01.45.21.8-1.91.8-1.41.41.42.3-2.3-0.71.1-0.90.9-0.50.5-0.70.2-0.1-0.10.30.41.30.10.3-0.1
Bone: cortical area0.10.20.9-0.60.7-0.30.2-0.2-0.2-0.91.00.1-0.40.1-0.1-0.20.20.0-0.30.1-0.2-0.0-0.1-0.50.3-0.50.1
Bone: cortical porosity2.32.54.9-1.91.6-2.22.1-2.1-2.2-2.22.21.5-1.71.8-1.82.1-2.11.30.90.40.50.20.2-0.70.70.71.0
Bone: cortical porosity2.02.25.1-1.91.7-2.01.8-1.8-2.1-2.32.31.3-1.51.7-1.72.0-2.01.00.70.20.30.00.1-0.90.40.60.6
Bone: cortical thickness0.20.30.8-0.70.5-0.40.6-0.6-0.4-0.40.40.7-0.60.5-0.50.4-0.40.70.70.80.60.80.70.30.90.20.8
Bone: cortical thickness0.30.41.00.4-0.30.9-0.70.70.81.0-1.0-0.10.7-0.60.6-0.60.60.00.10.70.50.80.71.00.30.00.3
Bone: cortical tissue density1.01.45.51.8-1.91.8-1.51.51.42.3-2.3-0.61.2-0.90.9-0.40.4-0.70.2-0.0-0.00.40.51.40.10.4-0.0
Condit. Reinf. active minus inactive responses0.60.71.9-1.00.7-1.41.4-1.4-1.1-0.60.60.7-1.20.8-0.80.9-0.90.80.90.10.2-0.3-0.2-1.00.4-0.30.3
Condit. Reinf. active-inactive response ratio0.80.91.51.2-1.20.6-0.70.70.91.0-1.1-1.20.5-1.11.1-0.90.9-0.9-0.7-1.2-1.0-1.2-1.1-0.6-0.6-1.1-0.7
Condit. Reinf. active responses2.12.64.9-2.22.0-2.22.2-2.2-2.0-1.41.41.8-2.11.7-1.71.7-1.71.81.81.21.20.50.6-0.71.10.51.0
Condit. Reinf. inactive responses5.36.511.8-3.43.2-2.92.7-2.7-3.1-2.72.73.1-2.73.0-3.03.0-3.02.52.52.22.01.51.5-0.21.51.71.5
Incentive salience index mean3.13.87.6-2.32.1-2.72.7-2.7-2.4-1.81.72.0-2.82.2-2.22.2-2.22.12.11.11.20.40.5-0.91.50.51.2
Condit. Reinf. lever presses5.67.813.0-3.23.2-3.43.3-3.3-3.4-2.42.43.2-3.63.3-3.33.2-3.23.03.12.22.21.41.5-0.42.31.51.9
Condit. Reinf. active minus inactive responses0.20.21.4-0.00.1-0.20.5-0.50.10.5-0.50.2-0.60.1-0.1-0.20.20.50.70.70.30.40.50.31.10.01.2
Condit. Reinf. active-inactive response ratio0.10.20.90.4-0.10.10.2-0.20.50.3-0.3-0.3-0.2-0.40.4-0.70.70.3-0.10.20.20.10.10.20.7-0.31.0
Condit. Reinf. active responses0.40.51.9-0.40.5-0.40.8-0.8-0.20.0-0.00.7-0.80.4-0.40.1-0.10.81.01.10.60.80.90.61.30.41.4
Condit. Reinf. inactive responses1.01.32.5-1.31.2-0.81.0-1.0-0.9-0.60.61.5-1.01.4-1.41.1-1.11.11.51.61.11.41.30.81.01.10.9
Condit. Reinf. lever presses1.31.84.4-1.71.5-1.71.7-1.7-1.6-1.81.81.2-2.11.4-1.41.5-1.51.00.90.60.30.20.2-0.81.00.21.1
Condit. Reinf. lever reinforcers received0.60.92.3-0.80.9-0.81.1-1.1-0.6-0.40.41.0-1.10.8-0.80.5-0.51.11.11.20.81.01.00.51.40.61.5
Conditioned reinforcement - actives0.40.71.61.2-1.11.2-1.11.11.31.3-1.3-0.80.7-1.01.0-1.11.1-0.6-0.4-0.1-0.20.20.10.80.0-0.1-0.1
Conditioned reinforcement - inactives2.23.24.7-1.81.9-2.12.1-2.1-2.0-1.81.82.0-2.22.0-2.02.0-2.02.01.71.51.61.21.20.21.71.31.5
Conditioned locomotion0.30.41.30.1-0.20.5-0.70.70.4-0.70.7-0.60.2-0.30.3-0.30.3-1.0-1.1-0.7-1.2-0.6-0.8-0.6-0.7-0.7-0.6
Patch foraging indifference point 0 sec3.97.311.0-3.33.2-2.93.1-3.1-3.1-2.42.43.2-3.12.8-2.83.0-3.02.92.92.62.41.92.10.02.12.11.9
Patch foraging indifference point AUC1.62.35.21.6-1.11.5-1.51.52.01.1-1.1-1.91.4-2.22.2-2.32.3-1.3-1.9-1.1-0.9-0.7-0.90.0-0.8-1.3-0.7
Delay disc. indifference point, 0s delay0.50.62.8-0.40.2-0.90.5-0.5-0.7-0.90.9-0.2-0.90.2-0.20.3-0.3-0.2-0.3-0.9-0.9-1.3-1.1-1.70.0-1.10.0
Delay disc. indifference point, 16s delay0.40.41.7-1.11.3-0.70.3-0.3-0.8-1.11.10.5-0.20.6-0.60.7-0.7-0.0-0.10.1-0.2-0.1-0.1-0.6-0.50.0-0.3
Delay disc. indifference point, 2s delay1.51.74.50.7-0.80.2-0.70.70.5-0.40.4-1.60.1-1.11.1-1.01.0-1.5-1.8-1.9-2.0-2.1-2.1-1.9-0.9-1.9-0.7
Delay disc. indifference point, 24s delay0.00.10.2-0.00.20.1-0.40.40.2-0.20.2-0.20.3-0.20.2-0.20.2-0.3-0.5-0.0-0.2-0.0-0.2-0.0-0.2-0.1-0.0
Delay disc. indifference point, 4s delay0.60.61.50.3-0.10.2-0.50.50.5-0.10.1-0.90.2-0.80.8-0.80.8-0.9-1.1-1.0-1.1-1.1-1.0-1.1-0.8-1.2-0.8
Delay disc. indifference point, 8s delay0.91.12.8-1.31.7-1.21.0-1.0-1.1-1.21.21.2-0.81.2-1.21.2-1.20.90.81.00.90.80.90.10.40.90.3
Indifference point function ln k1.52.76.0-1.61.1-1.51.6-1.6-2.0-1.21.22.1-1.82.5-2.52.4-2.41.52.11.21.11.01.10.31.01.60.9
Indifference point function log k1.52.76.0-1.61.1-1.51.6-1.6-2.0-1.21.22.1-1.82.5-2.52.4-2.41.52.11.21.11.01.10.31.01.60.9
Patch foraging total patch changes 0 sec3.97.311.8-3.43.3-3.03.1-3.1-3.2-2.42.43.2-2.92.8-2.83.1-3.12.92.92.52.41.92.1-0.01.92.11.8
Patch foraging total patch changes 12 sec1.31.75.6-2.12.4-1.71.5-1.5-1.5-1.71.71.4-1.41.1-1.11.0-1.01.30.91.11.10.70.8-0.50.60.40.7
Patch foraging total patch changes 18 sec0.50.82.0-1.01.0-0.40.7-0.7-0.6-0.30.31.1-0.30.5-0.50.8-0.81.11.01.31.41.31.30.90.71.20.8
Patch foraging total patch changes 24 sec1.52.55.4-2.32.3-1.82.0-2.0-1.9-1.81.81.8-1.41.5-1.51.6-1.61.61.31.41.11.01.1-0.21.01.01.2
Patch foraging total patch changes 6 sec1.72.65.4-1.41.3-0.71.4-1.4-1.2-0.30.32.0-1.11.3-1.31.5-1.51.92.02.32.12.22.31.61.62.11.8
Patch foraging time to switch 0 sec0.00.00.10.0-0.2-0.30.1-0.1-0.2-0.10.1-0.0-0.10.1-0.10.2-0.20.00.1-0.3-0.2-0.3-0.2-0.20.1-0.2-0.2
Patch foraging water rate 0 sec0.81.62.9-1.61.4-0.91.1-1.1-1.5-1.01.01.7-0.71.6-1.61.7-1.71.11.31.31.01.31.30.50.51.41.1
Patch foraging water rate 12 sec0.10.10.50.4-0.60.3-0.10.1-0.00.7-0.70.10.00.1-0.10.3-0.3-0.20.5-0.0-0.3-0.10.20.20.20.30.2
Patch foraging water rate 18 sec0.20.31.10.7-0.81.1-0.80.80.50.8-0.80.00.60.0-0.00.1-0.1-0.20.20.30.00.50.61.00.00.70.3
Patch foraging water rate 24 sec0.60.82.9-0.1-0.30.8-0.30.30.11.0-1.00.90.60.5-0.50.4-0.40.51.21.41.11.51.51.70.51.40.8
Patch foraging water rate 6 sec0.10.20.9-0.50.1-0.10.1-0.1-0.4-0.40.40.20.50.6-0.60.5-0.5-0.5-0.1-0.4-0.7-0.4-0.4-0.5-1.0-0.0-0.3
Seeking ratio, delayed vs. immediate footshock0.30.31.60.8-1.20.10.1-0.10.30.9-0.9-0.5-0.6-0.30.3-0.40.4-0.10.3-0.5-0.3-0.7-0.5-0.40.6-0.60.5
Distance traveled before self-admin1.31.74.60.5-0.6-0.1-0.70.70.4-0.30.3-1.40.6-0.80.8-0.80.8-1.6-1.6-2.0-2.0-2.1-2.1-1.9-1.7-1.9-1.3
Distance traveled after self-admin2.53.14.61.8-1.91.7-2.12.11.91.1-1.1-2.02.0-1.71.7-1.81.8-2.2-2.1-1.8-1.9-1.6-1.6-0.6-1.8-1.6-1.6
Extensor digitorum longus weight4.216.530.32.7-2.52.4-4.04.02.61.1-1.1-4.54.1-3.33.3-3.03.0-5.4-5.1-5.5-5.5-5.2-5.1-3.6-5.4-4.2-5.5
Bone: elastic displacement0.40.41.4-1.10.9-1.20.9-0.9-0.9-0.70.70.4-0.30.6-0.60.4-0.40.30.3-0.2-0.1-0.5-0.4-1.0-0.7-0.6-0.2
Bone: elastic work1.41.85.3-2.01.9-2.01.6-1.6-1.8-2.32.30.8-0.91.1-1.11.0-1.00.5-0.1-0.2-0.3-0.7-0.6-1.8-0.7-0.7-0.4
Bone: endosteal estimation0.20.41.4-0.30.6-0.40.0-0.0-0.1-1.21.2-0.4-0.4-0.20.2-0.50.5-0.4-0.9-0.7-0.6-0.7-0.9-1.0-0.3-0.8-0.5
Bone: endosteal perimeter0.30.71.90.00.3-0.2-0.40.40.3-0.90.9-0.8-0.4-0.70.7-0.90.9-0.8-1.2-1.1-1.0-1.2-1.2-1.4-0.5-1.3-0.8
Epididymis fat weight0.41.52.8-0.80.6-1.31.7-1.7-1.3-0.70.71.2-1.51.3-1.31.3-1.21.51.41.01.00.90.90.51.61.01.7
Delta time in closed arm before/after self-admin0.50.41.8-0.4-0.1-0.20.8-0.8-0.5-1.11.10.4-1.20.4-0.40.5-0.50.60.10.30.20.30.3-0.11.30.41.1
Delta time in open arm before/after self-admin0.10.10.2-0.00.4-0.3-0.00.00.2-0.10.1-0.30.1-0.30.3-0.40.40.1-0.4-0.20.2-0.2-0.2-0.2-0.5-0.5-0.3
Diff in mean of infusions in LGA sessions0.20.21.0-0.61.0-0.5-0.10.1-0.40.2-0.20.40.90.4-0.40.3-0.30.20.20.30.50.20.20.1-1.00.2-0.5
Delay discount exponential model param0.40.52.11.0-1.30.9-0.50.50.71.4-1.4-0.30.6-0.40.4-0.50.50.00.40.10.30.40.41.00.30.30.2
Extinction: sum of active levers before priming0.70.81.5-1.11.2-1.01.0-1.0-1.1-1.01.01.0-0.41.0-1.00.9-0.91.10.60.81.10.70.70.20.40.80.7
Active lever presses in extinction session 60.70.71.8-0.70.7-0.20.5-0.5-0.5-0.20.21.0-0.00.7-0.70.7-0.70.90.81.31.11.31.41.10.71.30.7
Bone: final force1.32.03.5-1.61.4-1.51.9-1.9-1.4-1.51.51.5-1.61.4-1.41.5-1.51.61.31.31.11.21.00.31.60.71.6
Bone: final moment1.22.03.9-1.71.5-1.72.0-2.0-1.5-1.61.61.4-1.61.5-1.51.4-1.41.41.21.00.80.80.7-0.11.40.51.3
Food consumed during 24 hour testing period0.20.31.4-0.70.8-0.70.6-0.6-0.3-1.21.20.2-0.90.5-0.50.2-0.20.4-0.2-0.0-0.0-0.1-0.2-0.60.3-0.4-0.1
Glucose0.40.71.90.6-0.41.4-1.21.21.00.5-0.5-0.61.3-1.21.2-0.90.9-0.4-0.80.30.10.60.50.9-0.10.30.1
Heart weight0.10.10.40.10.0-0.30.2-0.2-0.1-0.40.4-0.2-0.5-0.30.3-0.10.10.3-0.2-0.10.2-0.1-0.0-0.10.5-0.10.6
Delay discount hyperbolic model param0.40.41.60.8-1.00.8-0.30.30.51.3-1.3-0.00.5-0.20.2-0.20.20.20.60.30.50.60.61.10.40.60.3
Intermittent access intake day 1-15 change1.63.46.2-1.41.3-1.21.6-1.6-1.5-0.40.42.3-1.01.9-1.91.9-1.92.22.42.22.42.32.31.81.72.51.8
Intermittent access intake escalation1.93.86.3-1.51.4-1.51.9-1.9-1.7-0.60.62.4-1.42.1-2.12.1-2.12.32.52.22.42.32.21.71.92.52.0
Intermittent access intake escalation 20.70.82.10.1-0.40.10.5-0.5-0.10.4-0.40.8-0.60.5-0.50.5-0.51.01.11.01.11.31.21.41.41.31.4
Intermitt. access day 1 inactive lever presses0.20.82.4-0.10.0-0.00.5-0.5-0.11.0-1.00.9-0.20.5-0.50.4-0.41.11.51.31.31.31.41.31.21.11.2
Intermitt. access day 15 inactive lever presses0.81.72.6-1.21.2-1.11.3-1.3-1.3-0.70.71.6-1.11.4-1.41.4-1.41.61.61.41.61.21.40.61.41.41.5
Intermitt. access escalation Index0.00.00.1-0.1-0.1-0.1-0.00.0-0.2-0.20.2-0.00.20.1-0.10.1-0.1-0.1-0.1-0.1-0.2-0.2-0.3-0.2-0.3-0.00.1
Intermittent access day 1 total infusions0.91.53.3-1.81.8-1.21.0-1.0-1.3-1.31.31.6-0.61.5-1.51.4-1.41.11.01.31.21.21.10.40.41.20.1
Intermittent access day 15 total infusions2.74.06.4-2.01.9-1.82.0-2.0-1.9-1.21.22.5-1.62.2-2.22.2-2.22.32.42.32.32.22.11.21.82.31.7
Intermittent access terminal intake (last 3 days)1.41.93.6-1.11.0-0.71.1-1.1-1.0-0.50.51.7-0.81.4-1.41.3-1.31.61.61.81.81.91.71.41.41.91.2
Intermittent access total infusions2.63.15.2-1.81.8-1.31.5-1.5-1.6-1.01.02.3-1.01.9-1.91.9-1.92.02.02.22.12.22.01.41.42.21.1
Intermittent access day 1 locomotion2.12.74.5-2.01.8-1.51.6-1.6-1.7-1.41.42.1-1.52.0-2.02.0-2.01.61.81.81.51.51.50.61.21.61.2
Intermittent access day 15 total locomotion0.40.62.0-0.60.7-0.30.4-0.4-0.40.1-0.10.9-0.10.6-0.60.6-0.61.01.01.31.41.31.21.10.61.10.5
Intermittent access total locomotion1.21.42.4-1.31.2-1.01.1-1.1-1.1-0.80.71.5-0.91.3-1.31.4-1.41.31.41.41.41.31.20.70.91.31.0
Intermittent access standard deviation0.30.63.1-1.41.8-0.80.3-0.3-0.7-0.60.61.00.70.8-0.80.7-0.70.40.50.80.70.80.70.4-0.70.7-0.8
Left kidney weight1.15.110.1-2.42.1-2.82.8-2.8-2.6-2.72.72.3-3.22.7-2.72.5-2.52.31.91.41.41.00.9-0.42.01.31.7
Right kidney weight1.36.112.3-2.92.8-3.32.8-2.8-3.3-3.53.52.4-3.43.3-3.33.1-3.11.61.70.70.40.20.3-1.31.30.90.7
Cocaine induced anxiety0.81.24.3-1.10.9-1.50.9-0.9-1.2-1.51.50.2-1.30.8-0.80.9-0.9-0.3-0.0-1.0-1.2-1.4-1.3-2.1-0.5-0.9-0.6
Post-drug Anxiety0.70.72.5-0.80.5-1.41.2-1.2-1.1-0.80.80.6-1.60.9-0.90.9-0.90.50.8-0.1-0.1-0.6-0.4-1.10.5-0.30.4
Baseline Anxiety0.80.93.20.3-0.20.20.3-0.30.20.6-0.60.6-0.20.1-0.10.0-0.01.30.91.41.81.51.41.71.41.11.4
Tail length0.41.72.6-1.31.2-1.41.6-1.6-1.6-1.01.01.6-1.11.4-1.41.5-1.51.41.41.01.10.91.10.30.91.51.1
Length with tail0.62.44.9-2.12.0-2.21.7-1.7-2.2-1.31.31.9-1.22.1-2.12.1-2.11.21.80.70.70.40.6-0.50.21.10.2
Length without tail0.20.61.9-0.91.0-0.9-0.00.0-0.7-0.40.40.30.10.8-0.80.7-0.7-0.50.3-0.5-0.7-0.9-0.8-1.2-1.1-0.6-1.4
Times rat made contact with spout2.52.96.5-1.51.2-0.51.3-1.3-1.0-0.70.72.0-0.81.5-1.51.8-1.82.01.82.42.22.52.51.91.62.31.6
Lifetime Intake2.02.44.1-1.71.7-1.21.2-1.2-1.4-1.01.02.0-0.81.7-1.71.7-1.71.61.71.91.81.91.81.21.12.00.9
Liver weight, left0.81.45.9-1.31.4-1.91.1-1.1-1.2-1.31.30.1-1.00.7-0.70.4-0.4-0.1-0.0-0.9-1.0-1.6-1.5-2.4-0.7-1.5-1.0
Liver weight, right0.20.32.0-0.40.6-0.0-0.40.4-0.1-0.50.5-0.11.10.2-0.20.2-0.2-0.6-0.7-0.5-0.6-0.3-0.3-0.3-1.30.0-1.4
Locomotor activity2.64.114.9-1.71.6-2.10.6-0.6-1.7-2.72.7-0.1-1.01.0-1.01.0-1.0-1.5-1.1-2.4-2.8-2.9-2.7-3.9-2.4-2.3-2.8
Locomotor testing distance1.93.49.9-2.32.0-2.61.5-1.5-2.4-2.72.70.8-1.71.6-1.61.8-1.8-0.30.1-1.3-1.6-1.9-1.6-3.1-1.3-1.3-1.7
Locomotor testing rearing2.24.411.1-2.82.5-3.32.2-2.2-2.9-3.13.11.3-2.22.0-2.02.2-2.20.30.5-1.0-1.2-1.6-1.4-3.2-0.8-0.8-0.8
Locomotion in novel chamber1.21.53.9-1.81.7-1.31.1-1.1-1.5-2.02.01.4-0.91.5-1.51.6-1.60.80.60.70.60.70.4-0.10.30.90.2
Locomotion in novel chamber post-restriction0.20.31.10.10.20.2-0.30.30.4-0.20.2-0.60.8-0.70.7-0.70.7-0.4-1.0-0.4-0.3-0.3-0.3-0.2-0.6-0.6-0.5
Fecal boli incidents, locomotor time 10.91.44.3-2.02.1-1.20.7-0.7-1.5-2.02.01.2-0.11.4-1.41.4-1.40.10.20.3-0.20.10.1-0.7-0.80.4-1.0
Change in fecal boli incidents, locomotor task1.71.73.81.9-1.91.1-1.11.11.51.6-1.6-1.70.5-1.51.5-1.51.5-1.1-0.9-1.3-1.0-1.3-1.3-0.5-0.7-1.3-0.5
Time >=10cm from walls, locomotor time 10.90.92.0-1.00.8-1.01.1-1.1-1.2-1.11.11.2-1.41.3-1.31.3-1.30.61.10.70.20.40.4-0.20.70.80.3
Bouts of movement, locomotor time 10.70.81.51.0-1.11.2-1.21.20.81.2-1.2-0.71.2-0.60.6-0.60.6-1.2-0.5-0.7-1.0-0.5-0.60.2-0.9-0.3-0.7
Total resting periods, locomotor time 11.11.22.21.3-1.41.5-1.51.51.21.4-1.4-1.01.4-1.01.0-0.90.9-1.4-0.7-0.9-1.2-0.6-0.80.2-1.0-0.5-0.9
Rest time, locomotor task time 10.91.12.90.7-0.50.9-1.21.20.90.3-0.3-1.11.3-0.90.9-0.90.9-1.4-1.4-1.1-1.3-0.9-1.2-0.6-1.5-1.0-1.7
Distance moved, locomotor task time 10.71.12.8-0.20.4-0.61.0-1.0-0.50.5-0.50.9-1.10.4-0.40.5-0.51.51.51.41.71.21.41.01.51.01.7
Vertical activity count, locomotor time 10.00.10.5-0.20.1-0.40.1-0.1-0.2-0.10.1-0.1-0.20.1-0.10.2-0.2-0.3-0.0-0.6-0.5-0.6-0.6-0.7-0.5-0.4-0.3
Time >=10cm from walls, locomotor time 20.91.33.70.8-1.10.5-1.01.00.80.2-0.2-1.20.7-0.80.8-0.80.8-1.6-1.2-1.6-1.9-1.6-1.7-1.2-1.2-1.3-1.5
Bouts of movement, locomotor time 20.71.13.10.7-0.31.1-1.41.41.01.0-1.0-1.01.8-1.01.0-1.01.0-1.3-1.0-0.7-0.8-0.5-0.6-0.0-1.6-0.6-1.3
Total resting periods, locomotor time 20.40.72.70.30.00.9-1.21.20.70.7-0.7-0.71.6-0.70.7-0.60.6-1.1-0.8-0.5-0.7-0.3-0.40.1-1.6-0.4-1.4
Rest time, locomotor task time 20.20.31.5-0.40.80.3-0.50.50.1-0.20.20.11.20.0-0.0-0.00.0-0.2-0.50.20.20.30.30.3-1.10.2-1.2
Distance moved, locomotor task time 20.60.81.9-0.60.4-1.11.2-1.2-0.8-0.30.30.9-1.40.7-0.70.8-0.81.11.30.80.70.60.50.11.30.61.2
Vertical activity count, locomotor time 20.40.62.00.2-0.2-0.3-0.40.40.1-0.30.3-0.70.3-0.40.4-0.30.3-0.9-0.9-1.3-1.2-1.2-1.4-1.1-0.9-1.0-1.0
Light reinforcement 11.02.45.2-0.70.4-0.31.3-1.3-0.8-0.30.31.7-1.01.3-1.31.3-1.31.91.72.02.12.32.21.91.92.22.2
Light reinforcement 21.01.66.41.4-1.81.8-0.80.81.21.5-1.50.00.8-0.30.3-0.50.50.40.51.11.11.81.52.51.41.51.6
Bone: marrow area0.20.41.6-0.40.6-0.50.1-0.1-0.1-1.31.3-0.3-0.5-0.10.1-0.50.5-0.3-0.9-0.6-0.6-0.7-0.8-1.0-0.2-0.8-0.4
Bone: maximum diameter0.51.02.70.8-0.60.9-1.11.11.20.2-0.1-1.20.6-1.31.3-1.71.7-1.1-1.4-0.8-0.9-0.7-0.7-0.4-0.4-1.2-0.7
Bone: maximum force0.81.43.6-1.71.7-1.61.6-1.6-1.3-1.91.91.0-1.21.1-1.11.0-1.01.00.50.60.40.40.2-0.60.9-0.10.8
Bone: maximum moment0.91.64.4-1.81.9-1.91.8-1.8-1.5-2.12.11.0-1.41.2-1.21.1-1.10.90.40.40.10.1-0.1-1.00.7-0.40.6
Mean time between licks in bursts0.00.10.30.0-0.3-0.10.3-0.30.1-0.10.10.1-0.3-0.30.3-0.00.00.50.10.20.50.40.20.20.4-0.00.5
Mean num. licks in bursts0.00.10.2-0.40.4-0.00.3-0.30.0-0.50.50.2-0.20.2-0.2-0.00.00.10.00.3-0.10.30.20.10.1-0.0-0.1
Cd content in liver0.70.72.7-0.80.4-0.5-0.00.0-0.5-0.80.7-0.10.60.3-0.30.7-0.7-0.8-0.5-1.0-1.2-1.1-1.1-1.4-1.6-0.8-1.4
Co content in liver3.84.47.92.0-2.02.3-2.62.62.21.7-1.7-2.32.8-2.42.4-1.91.9-2.5-2.4-1.9-1.8-1.5-1.4-0.4-2.3-1.3-2.4
Cu content in liver0.60.71.40.8-0.91.0-1.21.21.21.0-1.0-0.70.7-1.01.0-0.90.9-0.8-0.5-0.3-0.5-0.3-0.4-0.0-0.8-0.6-0.8
Fe content in liver0.10.20.60.4-0.2-0.20.2-0.2-0.00.5-0.50.1-0.70.0-0.0-0.00.00.50.60.50.60.20.30.40.80.20.5
K content in liver1.11.02.7-0.00.10.10.2-0.2-0.30.1-0.11.0-1.00.6-0.60.8-0.81.11.21.51.51.51.41.41.51.71.4
Mg content in liver0.30.30.90.1-0.00.5-0.40.40.30.2-0.20.2-0.4-0.20.2-0.00.00.50.40.90.90.80.80.80.70.60.7
Mn content in liver0.20.20.60.5-0.50.8-0.70.70.50.1-0.1-0.40.6-0.60.6-0.40.4-0.5-0.6-0.2-0.20.00.00.2-0.40.3-0.4
Na content in liver1.51.64.5-1.61.3-2.01.3-1.3-1.8-2.12.10.6-1.61.0-1.01.2-1.20.20.1-0.5-0.5-1.2-1.0-2.1-0.2-0.7-0.2
Rb content in liver0.20.21.10.5-0.70.6-0.60.60.41.0-1.10.10.30.1-0.10.1-0.1-0.20.50.20.20.20.20.6-0.20.6-0.2
Se content in liver1.11.35.9-0.1-0.3-0.90.2-0.2-0.4-0.80.8-0.9-0.5-0.20.2-0.00.0-0.8-1.0-1.6-1.5-2.2-2.2-2.4-1.1-2.0-1.1
Sr content in liver1.21.12.40.5-0.40.4-0.70.70.8-0.20.2-1.20.7-1.01.0-1.01.0-1.2-1.5-1.3-1.4-1.3-1.3-1.2-1.0-1.6-1.3
Zn content in liver0.20.21.0-0.60.4-0.4-0.10.1-0.1-0.50.5-0.1-0.1-0.10.10.1-0.2-0.2-0.3-0.3-0.3-0.6-0.6-1.0-0.7-0.8-0.6
Bone: minimum diameter0.30.52.1-1.11.3-0.80.5-0.5-0.4-1.51.50.1-0.70.2-0.2-0.30.3-0.2-0.5-0.2-0.7-0.5-0.6-1.2-0.0-1.0-0.3
Time in familiar zone, hab. session 10.80.81.9-0.40.3-0.10.7-0.7-0.6-0.40.40.9-0.60.8-0.80.9-0.91.10.81.11.11.11.31.01.21.41.4
Time in novel zone, hab. session 14.84.86.92.0-1.81.9-2.52.52.32.1-2.1-2.42.5-2.62.6-2.52.5-2.4-2.0-2.0-1.9-1.7-1.8-0.7-2.3-2.1-2.2
Total zone transitions, hab. session 10.30.41.6-0.50.8-0.70.3-0.3-0.1-0.60.6-0.40.0-0.20.2-0.50.5-0.2-0.6-0.5-0.5-0.8-0.8-1.1-0.6-1.3-0.5
Total locomotion distance, hab. session 10.50.72.4-1.11.4-1.41.0-1.0-0.7-1.11.10.1-0.90.3-0.30.0-0.00.1-0.1-0.3-0.5-0.9-0.9-1.5-0.3-1.0-0.3
Locomotion velocity, hab. session 11.42.05.2-2.12.1-2.31.8-1.8-1.8-2.32.30.9-1.61.3-1.31.1-1.10.60.3-0.1-0.4-0.7-0.8-1.8-0.1-0.6-0.0
Time in familiar zone, hab. session 21.01.12.41.3-1.51.6-1.51.51.10.9-0.9-1.01.5-0.60.6-0.80.8-1.3-1.0-0.9-1.0-0.4-0.50.4-1.1-0.0-1.0
Time in novel zone, hab. session 20.20.20.9-0.71.0-0.80.7-0.7-0.3-0.30.30.1-0.3-0.40.4-0.10.10.50.10.20.3-0.1-0.1-0.60.1-0.60.2
Total zone transitions, hab. session 20.91.24.2-1.01.2-1.10.2-0.2-0.9-1.21.2-0.1-0.20.4-0.40.5-0.5-0.9-0.5-1.3-1.6-1.6-1.4-2.1-1.6-0.9-1.6
Total locomotion distance, hab. session 20.50.72.7-1.11.2-1.10.3-0.3-0.8-0.90.90.1-0.40.4-0.40.2-0.2-0.6-0.2-0.8-1.1-1.1-1.1-1.6-1.2-0.8-1.0
Locomotion velocity, hab. session 20.81.14.2-1.21.4-1.30.4-0.4-0.9-1.31.30.0-0.40.4-0.40.2-0.2-0.7-0.4-1.0-1.3-1.4-1.4-2.1-1.4-1.1-1.3
Novel to familiar place preference ratio1.51.63.9-1.72.0-1.51.8-1.8-1.4-0.70.71.4-0.90.8-0.80.9-0.91.71.41.61.31.01.30.01.00.61.1
Novelty place preference1.82.04.2-1.82.0-1.72.1-2.1-1.6-0.80.81.5-1.00.9-0.91.1-1.11.91.51.71.41.11.40.11.10.81.3
Time in novel zone, NPP test1.31.43.4-1.61.7-1.51.8-1.8-1.4-0.70.71.3-0.80.6-0.60.9-0.91.61.21.41.20.91.2-0.00.90.51.1
Total zone transitions, NPP test0.60.93.5-1.61.9-1.30.7-0.7-1.2-1.31.30.9-0.81.0-1.01.1-1.10.20.50.2-0.2-0.1-0.1-0.9-0.40.2-0.4
Total locomotion distance, NPP test1.31.75.2-2.12.3-1.81.4-1.4-1.6-1.71.71.5-1.41.5-1.51.4-1.40.91.10.80.40.50.3-0.60.30.60.3
Locomotion velocity, NPP test1.62.25.8-2.22.4-1.91.6-1.6-1.8-1.61.61.8-1.61.8-1.81.7-1.71.11.41.10.60.80.6-0.40.50.90.5
Intraocular pressure0.60.92.0-1.01.1-0.81.2-1.2-0.70.0-0.01.0-0.50.5-0.50.4-0.41.31.21.41.31.21.30.70.90.61.2
Delta distance traveled before/after self-admin1.92.05.01.8-1.72.2-1.91.91.92.0-2.0-1.22.0-1.41.4-1.51.5-1.1-0.8-0.1-0.30.30.21.3-0.5-0.1-0.7
Delta ambulatory time before/after self-admin0.81.02.51.1-1.11.6-1.41.41.31.4-1.4-0.71.6-0.90.9-0.90.9-0.9-0.5-0.1-0.30.30.21.0-0.60.1-0.9
Parametrial fat weight0.92.14.2-1.10.9-0.71.4-1.4-1.0-0.20.21.7-1.11.3-1.31.3-1.31.72.02.11.62.02.01.41.81.81.7
Pavlov. Cond. lever latency3.13.95.92.0-1.82.0-2.42.42.21.4-1.4-2.42.1-2.42.4-2.32.3-2.2-2.3-1.8-1.6-1.4-1.5-0.4-1.8-1.7-1.5
Pavlov. Cond. magazine entry latency0.70.91.5-0.50.9-0.81.0-1.0-0.7-0.20.21.0-0.91.1-1.10.7-0.71.11.21.21.01.01.10.81.21.10.8
Pavlov. Cond. change in total contacts1.92.04.0-1.82.0-1.91.8-1.8-1.7-1.11.11.7-1.41.8-1.81.5-1.51.41.61.30.90.70.8-0.20.90.70.6
Pavlov. Cond. index score3.24.06.6-1.92.0-2.12.4-2.4-2.2-1.41.42.4-2.12.6-2.62.3-2.32.22.31.91.71.61.60.61.81.91.5
Pavlov. Cond. latency score3.74.76.9-2.02.0-2.22.6-2.6-2.3-1.41.42.5-2.32.6-2.62.4-2.42.52.62.11.91.81.80.72.11.91.8
Pavlov. Cond. lever contacts4.25.17.9-2.22.0-2.12.6-2.6-2.4-1.61.52.7-2.32.8-2.82.7-2.72.52.72.11.91.91.90.82.12.21.8
Pavlov. Cond. magazine entry number0.50.71.40.8-1.20.9-1.01.00.80.6-0.6-0.90.7-1.11.1-0.80.8-0.9-0.9-0.9-0.7-0.8-0.7-0.4-0.7-0.8-0.4
Pavlov. Cond. intertrial magazine entries1.31.53.0-1.50.9-1.31.6-1.6-1.6-1.41.31.4-1.71.5-1.51.7-1.70.91.30.60.30.20.3-0.60.80.60.6
Pavlov. Cond. lever-magazine prob. diff.2.93.66.2-1.92.1-2.02.2-2.2-2.1-1.51.52.2-1.92.5-2.52.2-2.22.02.11.71.51.41.50.51.61.71.2
Pavlov. Cond. response bias1.01.32.5-0.91.2-1.11.2-1.2-1.1-0.70.71.3-1.11.6-1.61.4-1.41.21.31.00.91.00.90.51.01.20.6
Pavlov. Cond. lever latency1.11.54.11.6-1.31.6-1.31.31.52.0-2.0-0.61.6-1.11.1-1.31.3-0.0-0.10.40.80.90.81.80.10.6-0.2
Pavlov. Cond. magazine entry latency1.82.16.6-1.91.8-1.81.5-1.5-2.0-2.62.61.2-1.61.7-1.72.0-2.00.60.30.1-0.0-0.1-0.3-1.00.30.20.0
Pavlov. Cond. change in total contacts0.81.34.10.1-0.1-0.3-0.40.4-0.0-0.70.7-1.0-0.1-0.20.2-0.20.2-1.4-1.2-1.8-2.0-2.0-2.0-2.0-1.3-1.5-1.2
Pavlov. Cond. index score1.31.75.4-1.61.5-1.71.1-1.1-1.6-2.32.30.6-1.41.3-1.31.6-1.6-0.1-0.2-0.6-0.9-1.0-1.0-1.8-0.4-0.5-0.4
Pavlov. Cond. latency score1.31.85.3-1.61.4-1.71.2-1.2-1.7-2.32.30.6-1.61.4-1.41.6-1.6-0.0-0.1-0.6-0.8-1.0-1.1-1.8-0.2-0.5-0.3
Pavlov. Cond. lever contacts1.31.75.1-1.71.5-1.71.3-1.3-1.7-2.32.30.8-1.61.3-1.31.6-1.60.10.1-0.3-0.8-0.8-0.7-1.7-0.1-0.40.0
Pavlov. Cond. magazine entry number0.91.14.01.3-1.31.3-1.21.21.32.0-2.0-0.81.3-1.21.2-1.31.3-0.5-0.1-0.10.00.10.20.8-0.4-0.2-0.2
Pavlov. Cond. intertrial magazine entries2.03.17.4-1.00.9-0.41.3-1.3-0.7-0.20.21.9-1.41.2-1.21.0-1.02.22.12.62.42.72.72.12.52.22.2
Pavlov. Cond. lever-magazine prob. diff.1.01.34.5-1.31.2-1.41.0-1.0-1.4-2.12.10.4-1.31.1-1.11.3-1.3-0.1-0.3-0.7-0.9-1.0-1.0-1.7-0.3-0.5-0.3
Pavlov. Cond. response bias1.52.16.9-2.01.8-1.81.3-1.3-1.8-2.62.60.9-1.61.5-1.51.7-1.70.0-0.0-0.3-0.9-0.8-0.7-1.8-0.3-0.4-0.3
Time in closed arm before self-admin0.20.20.60.8-0.80.7-0.60.60.60.5-0.5-0.50.1-0.40.4-0.40.4-0.6-0.3-0.3-0.5-0.2-0.20.2-0.1-0.2-0.0
Time in closed arm after self-admin0.10.10.2-0.0-0.30.30.1-0.1-0.1-0.10.10.3-0.30.2-0.20.3-0.30.20.30.30.20.30.30.30.40.40.4
Time in open arm before self-admin0.10.20.60.1-0.20.3-0.30.30.20.3-0.3-0.40.6-0.40.4-0.30.3-0.5-0.3-0.5-0.4-0.4-0.4-0.3-0.5-0.4-0.8
Time in open arm after self-admin0.30.40.90.6-0.30.0-0.40.40.50.1-0.1-0.80.4-0.70.7-0.70.7-0.5-0.9-0.9-0.5-0.7-0.8-0.4-0.6-0.8-0.7
Bone: periosteal estimation0.20.41.1-0.20.4-0.2-0.10.10.2-1.01.0-0.5-0.3-0.30.3-0.70.7-0.4-0.9-0.6-0.6-0.6-0.7-0.9-0.1-1.0-0.3
Bone: periosteal perimeter0.20.41.30.10.10.2-0.40.40.5-0.50.5-0.7-0.0-0.70.7-1.01.0-0.6-1.0-0.5-0.6-0.6-0.7-0.7-0.1-1.1-0.4
Bone: post-yield work0.20.31.40.10.10.6-0.10.10.5-0.00.00.20.2-0.10.1-0.20.20.3-0.00.90.61.10.81.20.90.70.9
Progressive ratio test 1 active lever presses0.30.41.7-0.50.70.1-0.00.0-0.10.1-0.10.70.40.3-0.30.3-0.30.50.51.11.01.31.11.20.11.00.0
Progressive ratio test 1 breakpoint0.30.31.4-0.40.60.1-0.20.20.00.2-0.20.60.50.2-0.20.2-0.20.40.41.00.91.21.01.1-0.00.9-0.1
Progressive ratio test 1 inactive lever presses2.02.87.0-1.00.9-0.40.9-0.9-0.70.6-0.62.0-0.21.2-1.21.2-1.22.02.32.52.52.62.62.31.72.41.9
Progressive ratio test 2 active lever presses0.60.72.7-0.50.8-0.00.3-0.3-0.2-0.10.10.90.20.5-0.50.5-0.50.90.71.31.41.61.51.50.61.30.5
Progressive ratio test 2 breakpoint0.70.82.5-0.71.0-0.20.4-0.4-0.4-0.30.31.00.00.6-0.60.6-0.61.00.71.31.41.61.51.40.61.30.5
Progressive ratio test 2 inactive lever presses1.21.93.5-1.31.4-1.11.3-1.3-1.2-0.60.61.7-0.81.4-1.41.4-1.41.71.61.81.91.81.71.21.31.71.3
Incentive Sensitization - Responses0.30.41.1-0.50.7-0.20.5-0.5-0.3-0.50.60.6-0.30.5-0.50.5-0.50.70.30.70.91.01.00.80.60.90.6
Incentive Sensitization - Breakpoint0.50.61.3-0.70.9-0.40.7-0.7-0.5-0.70.70.9-0.50.7-0.70.7-0.70.90.50.91.01.21.10.80.71.00.7
Sum of active levers in priming session hrs 5-62.22.13.91.9-1.72.0-1.81.81.72.0-2.0-1.61.8-1.71.7-1.71.7-1.1-1.1-0.7-0.6-0.4-0.40.7-0.3-0.5-0.6
Progressive ratio0.40.62.20.4-0.41.2-1.21.20.70.8-0.8-0.11.5-0.20.2-0.20.2-0.8-0.30.2-0.20.60.30.9-1.10.7-1.2
Food seeking constrained by brief footshock5.97.216.63.0-2.73.5-3.83.83.23.4-3.4-2.44.1-2.62.6-2.62.6-2.8-2.0-1.4-1.4-0.7-0.80.9-2.8-0.7-2.7
Seeking ratio, punishment vs. effort1.01.42.51.5-1.41.0-1.11.11.31.1-1.1-1.60.7-1.61.6-1.51.5-1.0-1.1-1.2-1.0-1.2-1.0-0.5-0.3-1.4-0.2
Retroperitoneal fat weight0.41.94.4-0.2-0.2-0.41.3-1.3-0.70.4-0.41.4-1.21.2-1.21.3-1.31.62.01.71.51.71.61.62.11.91.9
Reaction time number correct1.63.15.82.1-2.02.4-2.22.22.12.1-2.1-1.82.3-2.02.0-1.91.9-1.8-1.5-1.0-1.1-0.6-0.70.6-1.1-0.8-1.4
Reaction time mean minus median0.41.13.6-1.31.5-1.71.1-1.1-1.1-1.41.40.4-1.00.8-0.80.4-0.40.00.2-0.6-0.7-1.1-1.0-1.9-0.7-1.0-1.0
Reaction time mean minus median AUC0.20.41.3-0.91.1-1.20.8-0.8-0.6-1.11.10.4-0.80.5-0.50.2-0.20.30.2-0.2-0.1-0.3-0.4-1.0-0.0-0.5-0.3
Reaction time num false alarms0.10.10.5-0.30.5-0.1-0.20.2-0.1-0.60.6-0.3-0.5-0.30.3-0.20.2-0.3-0.5-0.1-0.2-0.3-0.4-0.50.1-0.7-0.4
Reaction time num false alarms AUC0.10.10.4-0.20.4-0.0-0.20.2-0.0-0.60.6-0.3-0.5-0.40.4-0.20.2-0.1-0.50.0-0.0-0.2-0.2-0.30.5-0.6-0.1
Reaction time trials correct on left1.63.15.82.1-2.02.4-2.22.22.12.1-2.1-1.82.3-2.02.0-1.91.9-1.8-1.5-1.0-1.1-0.6-0.70.6-1.1-0.8-1.4
Reaction time trials on left1.63.05.62.1-2.02.4-2.22.22.12.1-2.1-1.82.2-2.02.0-1.91.9-1.7-1.4-0.9-1.0-0.5-0.60.6-1.0-0.7-1.3
Reaction time mean0.50.83.5-0.40.6-1.20.7-0.7-0.6-1.11.1-0.3-1.00.2-0.2-0.10.1-0.2-0.4-1.1-0.8-1.4-1.3-1.9-0.5-1.3-0.8
Reaction time mean AUC0.61.04.4-0.40.5-1.20.6-0.6-0.5-1.01.0-0.4-0.80.0-0.0-0.20.2-0.4-0.6-1.4-1.0-1.7-1.6-2.1-0.7-1.5-1.0
Median of all reaction times0.40.62.30.1-0.0-0.70.3-0.3-0.2-0.70.7-0.6-0.7-0.20.2-0.30.3-0.3-0.6-1.2-0.8-1.4-1.3-1.5-0.4-1.3-0.6
Reaction time omissions0.10.20.6-0.40.6-0.60.6-0.6-0.2-0.10.10.3-0.7-0.10.1-0.30.30.70.50.40.50.10.1-0.30.6-0.30.6
Reaction time false alarm rate0.60.82.0-1.21.2-1.00.9-0.9-1.0-1.41.40.8-1.40.7-0.70.8-0.80.80.40.70.70.40.4-0.21.00.20.7
Reaction time premature initiation rate0.81.13.91.6-2.01.3-1.01.01.22.0-2.0-0.81.0-0.90.9-0.80.8-0.80.0-0.5-0.6-0.20.00.7-0.20.10.3
Reaction time premature initiations2.13.79.22.7-3.02.6-2.22.22.43.0-3.0-1.82.2-2.02.0-1.91.9-1.7-0.8-1.0-1.1-0.5-0.31.0-0.8-0.4-0.4
Std. dev. reaction times0.40.73.1-0.70.9-1.20.7-0.7-0.5-0.90.9-0.1-0.80.2-0.2-0.20.2-0.2-0.2-0.9-0.8-1.2-1.2-1.8-0.7-1.4-0.9
Reaction time trials completed1.63.05.62.1-2.02.4-2.22.22.12.1-2.1-1.82.2-2.02.0-1.91.9-1.7-1.4-0.9-1.0-0.5-0.60.6-1.0-0.7-1.3
Reaction time trials AUC1.63.05.82.1-2.12.4-2.22.22.12.0-2.0-1.82.2-2.02.0-1.91.9-1.8-1.5-1.0-1.1-0.6-0.70.6-1.1-0.8-1.3
Run reversals in cocaine runway, females0.10.10.40.4-0.00.4-0.30.30.4-0.20.2-0.3-0.0-0.40.4-0.30.30.0-0.60.10.20.20.00.30.10.10.1
Run reversals in cocaine runway, males1.11.14.0-1.82.0-1.60.8-0.8-1.3-1.81.81.0-0.01.0-1.01.0-1.00.4-0.00.20.30.1-0.1-0.8-1.00.1-1.0
Latency to leave start box in cocaine runway1.31.52.61.0-1.10.7-1.01.01.00.7-0.7-1.41.1-1.11.1-1.21.2-1.5-1.3-1.6-1.6-1.5-1.4-1.0-1.3-1.5-1.2
Latency to leave start box in cocaine runway, F0.70.81.70.5-0.60.3-0.70.70.60.5-0.5-1.00.9-0.80.8-0.80.8-1.1-0.9-1.1-1.1-1.2-1.1-1.0-1.3-1.2-1.1
Latency to leave start box in cocaine runway, M1.21.12.41.0-1.20.9-1.01.01.00.4-0.4-1.20.8-0.90.9-0.90.9-1.4-1.2-1.5-1.6-1.2-1.2-0.7-0.8-1.2-0.9
Std. dev. time between licks in bursts1.11.55.1-1.21.2-2.22.2-2.2-1.4-1.21.30.6-2.30.5-0.50.6-0.61.40.80.20.6-0.4-0.2-1.41.1-0.61.1
Total sessions with >9 infusions0.30.40.8-0.80.7-0.50.4-0.4-0.7-0.80.80.8-0.60.8-0.80.9-0.90.20.50.40.10.50.40.10.20.60.3
Short access day 1 total inactive lever presses3.85.011.8-3.23.4-2.52.2-2.2-2.8-2.72.72.7-1.62.7-2.72.7-2.71.81.71.91.51.41.5-0.00.71.70.6
Short access day 10 total inactive lever presses0.30.61.3-0.70.4-0.20.5-0.5-0.60.1-0.11.1-0.20.7-0.70.9-0.90.81.21.10.81.11.10.90.71.11.0
Short access day 1 total infusions0.40.61.3-1.11.0-0.40.4-0.4-0.7-1.01.01.1-0.41.0-1.01.0-1.00.40.60.80.30.90.80.40.30.90.1
Short access day 10 total infusions1.01.33.9-1.92.0-1.50.9-0.9-1.5-1.81.81.1-0.51.3-1.31.3-1.30.40.30.30.10.0-0.0-0.8-0.50.3-0.5
Short access total infusions0.91.22.9-1.61.7-1.10.8-0.8-1.3-1.31.31.4-0.41.4-1.41.4-1.40.70.80.90.70.90.80.30.11.1-0.0
Short access day 1 locomotion0.70.93.2-1.00.8-0.80.4-0.4-1.0-1.81.80.2-0.70.7-0.70.7-0.7-0.7-0.5-0.8-1.3-1.0-1.0-1.6-0.6-0.7-0.7
Short access day 10 total locomotion0.20.31.4-0.60.5-0.70.5-0.5-0.7-1.21.20.3-1.00.5-0.50.6-0.60.1-0.1-0.1-0.2-0.3-0.4-0.70.0-0.20.2
Short access total locomotion0.70.92.7-1.31.1-1.20.8-0.8-1.2-1.61.60.8-1.21.1-1.11.1-1.10.00.2-0.0-0.5-0.3-0.3-1.0-0.0-0.00.1
One hour access (0.3 mA shock)1.51.84.3-1.92.1-1.31.1-1.1-1.6-1.41.41.7-0.61.7-1.71.7-1.71.01.11.31.01.21.10.40.21.4-0.1
Compulsive drug intake2.22.64.1-1.81.6-1.61.8-1.8-2.0-1.51.51.9-1.81.8-1.82.0-2.01.71.71.41.31.01.20.11.51.41.2
One hour access (shock baseline)0.10.10.8-0.40.7-0.1-0.30.3-0.1-0.20.20.20.70.2-0.20.1-0.1-0.3-0.2-0.0-0.10.20.00.1-0.90.1-0.9
Social response proportion3.43.87.32.6-2.62.6-2.32.32.62.6-2.6-2.01.8-2.72.7-2.32.3-1.5-1.2-0.8-0.8-0.3-0.40.8-0.4-0.8-0.7
Social responses1.11.43.31.8-1.81.5-0.90.91.61.7-1.7-1.10.4-1.81.8-1.51.5-0.3-0.4-0.2-0.10.10.20.60.6-0.50.4
Social time0.30.41.3-0.50.6-1.11.0-1.0-0.7-0.90.90.2-1.10.3-0.30.3-0.30.80.2-0.20.3-0.4-0.4-0.90.7-0.60.4
Soleus weight3.911.520.32.8-2.62.8-4.14.12.92.0-2.0-3.73.8-3.13.1-3.03.0-4.5-3.8-3.8-4.1-3.4-3.5-1.8-4.2-3.0-4.3
Bone: stiffness0.71.21.9-1.31.3-1.11.2-1.2-1.2-1.41.41.2-1.41.1-1.11.3-1.31.00.91.00.70.80.8-0.01.40.61.1
Tibialis anterior weight2.48.119.71.3-1.21.4-2.82.81.3-0.10.1-2.82.7-1.71.7-1.41.4-4.1-3.6-4.0-4.3-3.7-3.8-2.9-4.2-2.9-4.4
Time to tail flick, vehicle, before self-admin3.43.57.3-1.71.7-1.11.4-1.4-1.6-0.30.32.4-0.91.9-1.91.9-1.92.32.42.62.72.42.51.71.52.51.6
Time to tail flick, vehicle, after self-admin1.31.76.11.2-0.71.8-1.71.71.32.5-2.5-0.52.3-0.90.9-1.01.0-0.70.00.40.40.70.71.6-0.90.4-0.9
Time to tail flick, test, before self-admin1.51.62.5-1.21.1-1.31.5-1.5-1.3-1.41.41.4-1.61.3-1.31.4-1.41.51.01.11.20.90.90.31.41.01.1
Time to tail flick, test, after self-admin0.80.92.80.7-0.60.60.0-0.00.41.3-1.30.3-0.5-0.20.2-0.20.20.81.11.21.21.21.31.51.71.01.4
Delta time to tail flick, vehicle, before/after SA1.31.33.21.3-0.91.5-1.41.41.41.7-1.7-1.01.8-1.11.1-1.21.2-1.1-0.6-0.4-0.5-0.0-0.00.8-0.9-0.3-0.8
Delta time to tail flick, test, before/after SA1.81.85.52.0-1.92.0-1.41.41.82.3-2.3-1.10.9-1.51.5-1.61.6-0.6-0.20.1-0.10.40.51.40.60.00.7
Tibia length7.520.631.1-5.44.7-5.15.4-5.4-5.3-4.54.55.3-5.55.6-5.65.4-5.44.64.73.73.22.82.9-0.03.23.13.1
Ambulatory time before self-admin0.40.61.6-0.10.1-0.4-0.30.3-0.0-0.50.5-0.70.4-0.20.2-0.20.2-0.8-1.0-1.2-1.1-1.3-1.3-1.3-1.3-1.0-0.8
Ambulatory time after self-admin2.32.75.51.1-1.31.1-1.81.81.30.6-0.6-1.71.9-1.21.2-1.21.2-2.2-1.9-2.0-2.2-1.8-1.9-1.1-2.4-1.6-2.0
Bone: tissue strength0.30.31.1-0.50.8-0.91.0-1.0-0.5-0.70.70.1-1.00.1-0.10.2-0.20.60.10.00.2-0.2-0.2-0.60.6-0.30.4
Total heroin consumption0.30.42.2-0.40.8-0.2-0.50.5-0.1-0.30.3-0.21.1-0.00.0-0.10.1-0.6-0.7-0.6-0.4-0.5-0.6-0.5-1.5-0.4-1.3
Bone: trabecular number0.30.51.1-0.81.1-0.70.8-0.8-0.5-0.91.00.7-0.80.7-0.70.5-0.50.80.40.60.60.60.40.20.70.20.4
Bone: trabecular spacing0.81.01.71.1-1.00.8-1.21.20.90.8-0.8-1.20.8-1.01.0-1.01.0-1.3-0.9-1.3-1.1-1.2-1.2-0.6-0.9-1.1-0.7
Bone: trabecular thickness1.72.13.4-1.81.7-1.41.8-1.8-1.7-1.71.71.7-0.91.6-1.61.8-1.81.61.01.41.11.31.20.40.81.11.0
Bone: trabecular tissue density0.50.71.60.7-0.60.5-1.01.00.60.2-0.2-0.90.8-0.60.6-0.50.5-1.2-1.0-1.2-1.2-1.0-1.0-0.8-1.1-0.7-1.0
Water consumed over 24 hours0.10.10.6-0.60.5-0.30.1-0.1-0.2-0.70.80.20.10.3-0.30.5-0.5-0.1-0.3-0.1-0.2-0.00.0-0.3-0.4-0.1-0.6
Number of responses in last shaping day0.30.30.80.3-0.30.6-0.70.70.50.1-0.1-0.60.9-0.50.5-0.60.6-0.6-0.9-0.4-0.4-0.4-0.5-0.1-0.6-0.5-0.4