Hub : Genes

Nudt15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr15_48711928_48713567 0.16 0.08 2.0e-10 0.12 0.11 0.11 0.12 1.6e-11 1.2e-10 9.9e-11 4.8e-11
2 PL intron excision ratio chr15_48711928_48713263 0.46 0.16 5.6e-17 0.15 0.16 0.16 0.15 1.8e-16 2.2e-17 7.3e-17 4.9e-16
3 PL intron excision ratio chr15_48711928_48713567 0.43 0.16 0.0e+00 0.16 0.17 0.16 0.16 2.3e-17 5.6e-18 2.9e-17 3.4e-17
4 RMTg intron excision ratio chr15_48711928_48713567 0.16 0.09 6.3e-03 0.02 0.03 0 0.03 8.7e-02 5.5e-02 2.8e-01 7.3e-02
5 NAcc intron excision ratio chr15_48711928_48713567 0.09 0.04 6.7e-10 0.05 0.08 0.06 0.08 4.6e-06 5.7e-10 1.2e-07 1.8e-09
6 Adipose intron excision ratio chr15_48711928_48713567 0.02 0.02 7.1e-03 0.02 0.01 0.01 0.01 5.4e-03 1.3e-02 1.7e-02 1.3e-02
7 BLA intron excision ratio chr15_48711928_48713263 0.08 0.06 3.4e-03 0.03 0.04 0.02 0.03 1.7e-02 4.7e-03 1.9e-02 9.5e-03
8 BLA intron excision ratio chr15_48711928_48713567 0.08 0.06 3.7e-03 0.02 0.04 0.02 0.03 1.8e-02 5.2e-03 2.2e-02 1.1e-02
9 LHb gene expression Nudt15 0.52 0.16 2.6e-09 0.27 0.32 0.38 0.33 3.3e-07 2.1e-08 4.3e-10 9.5e-09
10 pVTA intron excision ratio chr15_48711928_48713567 0.33 0.13 6.5e-09 0.24 0.19 0.21 0.22 1.0e-10 1.3e-08 2.3e-09 9.1e-10
11 Adipose gene expression Nudt15 0.06 0.04 4.3e-07 0.04 0.05 0.05 0.05 3.0e-05 2.8e-06 2.0e-06 1.7e-06
12 Liver intron excision ratio chr15_48711928_48713567 0.08 0.04 1.6e-08 0.06 0.06 0.07 0.06 1.8e-07 1.6e-07 5.5e-08 1.1e-07
13 Brain mRNA stability Nudt15 0.09 0.04 3.7e-08 0.08 0.1 0.1 0.1 5.6e-08 9.1e-10 2.2e-09 4.1e-09
14 PL gene expression Nudt15 0.41 0.1 0.0e+00 0.39 0.4 0.41 0.41 1.3e-45 3.0e-47 9.7e-48 5.8e-48
15 pVTA gene expression Nudt15 0.44 0.14 5.2e-12 0.24 0.28 0.3 0.3 5.6e-11 1.1e-12 2.7e-13 2.3e-13
16 Brain gene expression Nudt15 0.55 0.14 0.0e+00 0.38 0.37 0.36 0.38 1.0e-36 5.8e-36 5.7e-35 6.0e-37
17 BLA gene expression Nudt15 0.54 0.15 0.0e+00 0.31 0.32 0.3 0.32 6.3e-17 1.1e-17 9.5e-17 5.4e-18
18 NAcc gene expression Nudt15 0.37 0.1 0.0e+00 0.33 0.42 0.4 0.42 3.2e-39 2.2e-53 4.0e-50 1.9e-52
19 IL gene expression Nudt15 0.36 0.14 6.6e-07 0.25 0.24 0.22 0.27 9.7e-07 1.9e-06 5.6e-06 3.6e-07
20 OFC gene expression Nudt15 0.23 0.11 1.9e-04 0.17 0.14 0.11 0.14 9.4e-05 4.4e-04 1.8e-03 2.7e-04
21 Liver gene expression Nudt15 0.05 0.03 1.1e-05 0.05 0.04 0.04 0.04 5.5e-06 1.2e-05 3.8e-05 9.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.40.62.31.01.2-1.1-0.9-0.80.61.5-1.5-0.10.90.60.20.30.50.70.60.30.00.3-0.2-0.5
Area under the delay curve0.50.52.00.81.2-1.1-1.1-1.00.71.4-1.4-0.30.60.70.10.20.10.40.2-0.1-0.4-0.1-0.10.1
BMI with tail0.10.20.8-0.2-0.10.20.50.6-0.6-0.00.0-0.30.30.3-0.30.10.70.60.60.70.90.7-0.1-0.3
BMI without tail0.51.03.00.30.1-0.00.10.50.30.3-0.3-1.50.40.70.40.81.60.91.31.61.71.3-1.3-1.7
Body weight0.72.75.62.02.0-2.0-1.6-1.71.31.6-1.6-1.62.42.21.91.91.32.31.31.20.41.4-0.7-0.6
Weight adjusted by age1.51.74.1-1.1-1.31.10.1-0.1-0.2-0.80.81.4-1.3-1.3-0.7-1.3-1.9-1.7-1.9-2.0-1.8-2.00.90.8
Bone surface0.40.72.91.11.4-1.3-1.2-1.10.71.7-1.7-0.40.90.30.10.20.20.60.2-0.0-0.4-0.10.0-0.2
Bone volume0.50.83.61.11.5-1.4-1.0-0.90.41.9-1.9-0.10.90.5-0.10.10.20.60.30.1-0.3-0.10.2-0.0
Breakpoint value in progressive ratio session0.30.32.1-0.00.5-0.40.70.3-1.4-0.40.40.00.10.1-0.6-0.20.00.10.00.10.00.21.41.1
Number of licking bursts0.91.02.70.90.8-0.70.00.10.10.1-0.1-1.20.91.30.61.21.51.21.51.61.51.3-0.8-0.8
Context. condit. distance diff. score1.92.38.9-0.6-1.11.21.72.2-0.9-1.21.1-2.0-0.10.1-0.60.71.90.91.52.13.02.2-1.5-1.8
Locomotion velocity, session 11.11.12.6-0.7-0.30.20.1-0.2-0.6-0.00.00.9-0.8-1.1-0.8-1.3-1.6-1.2-1.6-1.6-1.6-1.61.41.4
Locomotion distance, session 10.50.61.80.91.3-1.3-1.1-1.30.61.2-1.2-0.20.40.20.4-0.1-0.30.0-0.2-0.5-1.1-0.50.50.6
Locomotion velocity, session 20.30.41.10.60.8-0.9-0.8-0.90.50.6-0.6-0.1-0.30.10.3-0.2-0.4-0.6-0.3-0.5-1.0-1.10.40.5
Locomotion distance, session 21.42.05.41.62.3-2.3-1.9-2.10.82.2-2.20.10.80.70.7-0.1-0.60.1-0.3-0.9-1.8-1.01.11.0
Locomotion velocity, session 30.30.30.9-0.6-0.70.80.80.9-0.5-0.70.7-0.2-0.6-0.5-0.5-0.30.3-0.30.20.30.70.1-0.3-0.2
Locomotion distance, session 30.50.52.1-0.0-0.30.30.70.9-0.3-0.40.4-1.10.10.2-0.10.41.00.50.81.11.41.1-0.8-0.8
Stereotopy head waving bouts, day 30.91.02.5-1.0-1.00.90.70.4-0.8-1.11.10.7-1.2-0.9-0.6-1.0-1.1-1.4-1.2-1.0-1.0-1.61.01.0
Stereotopy head waving duration, day 30.80.92.4-0.6-0.30.20.1-0.2-0.6-0.10.11.1-0.7-0.4-0.5-1.1-1.4-1.0-1.4-1.4-1.5-1.51.41.3
Locomotion velocity, session 73.94.215.30.1-0.81.01.62.2-0.2-1.51.5-2.5-0.0-0.3-0.21.43.11.12.73.13.92.7-2.7-3.0
Locomotion distance, session 72.22.810.6-0.3-1.01.11.62.1-0.5-1.31.3-1.6-0.1-0.8-0.50.82.40.92.12.33.32.3-2.0-2.2
Stereotopy head waving bouts, day 70.40.41.70.70.9-0.9-0.8-1.10.50.5-0.5-0.6-0.10.40.4-0.1-0.5-0.5-0.4-0.4-1.1-1.30.40.3
Stereotopy head waving duration, day 70.30.41.8-0.00.2-0.2-0.3-0.60.0-0.10.2-0.0-0.50.10.1-0.4-0.9-0.8-0.8-0.7-1.2-1.30.80.7
Locomotion velocity, session 80.30.31.00.20.3-0.30.30.4-0.30.1-0.1-0.60.10.60.00.40.90.40.81.01.01.0-0.3-0.6
Locomotion distance, session 81.01.54.61.31.4-1.3-0.5-0.20.51.2-1.3-2.11.01.20.61.01.61.31.51.51.31.5-0.9-1.1
Degree of sensitization distance0.90.92.9-0.3-0.70.81.11.3-0.4-1.01.0-0.3-0.5-1.0-0.60.21.30.11.21.11.70.9-1.0-1.2
Degree of sensitization stereotypy0.30.30.90.80.9-1.0-0.7-0.90.50.5-0.5-0.50.30.80.70.40.10.10.20.2-0.4-0.40.10.0
Conditioned locomotion0.30.41.4-0.9-1.21.20.91.0-0.5-0.90.9-0.2-0.4-0.4-0.4-0.20.0-0.1-0.30.00.50.3-0.2-0.2
Cocaine response after cond. corrected2.73.05.6-2.3-2.42.42.32.1-2.0-2.22.22.1-1.7-2.1-1.9-1.5-0.7-1.4-0.8-0.70.2-0.80.90.8
Cocaine response after cond. not corrected0.91.01.8-1.3-1.31.31.31.3-1.1-1.21.21.0-1.0-1.3-1.2-0.9-0.3-0.8-0.3-0.30.3-0.40.40.3
Cocaine response before conditioning3.44.17.32.72.7-2.7-2.4-2.22.32.5-2.5-2.72.02.12.11.81.31.71.31.10.21.0-1.4-1.2
Saline control response1.41.83.71.71.8-1.8-1.0-1.10.61.1-1.1-1.61.91.91.31.51.31.81.31.10.61.3-0.3-0.6
Bone: connectivity density0.71.12.01.20.8-0.9-1.0-0.81.10.7-0.7-0.91.41.01.21.20.91.40.90.70.61.3-1.1-1.2
Bone: cortical apparent density1.31.75.2-1.6-2.02.02.02.0-1.4-2.32.30.5-1.2-0.8-0.9-0.40.1-0.7-0.10.31.10.4-0.0-0.1
Bone: cortical area0.10.10.60.20.4-0.3-0.2-0.1-0.00.7-0.70.1-0.2-0.6-0.6-0.40.1-0.30.1-0.0-0.1-0.40.10.0
Bone: cortical porosity2.42.65.41.92.1-2.1-2.3-2.21.82.3-2.3-0.92.02.21.91.30.11.60.30.0-0.70.3-0.5-0.4
Bone: cortical porosity2.02.25.51.61.9-1.9-2.1-2.01.62.3-2.3-0.61.82.11.51.00.01.40.2-0.1-0.70.2-0.4-0.3
Bone: cortical thickness0.20.40.90.80.7-0.6-0.3-0.20.30.4-0.4-0.90.50.20.00.60.90.60.90.80.70.6-0.5-0.6
Bone: cortical thickness0.40.41.20.0-0.10.20.80.8-0.6-0.70.7-0.8-0.5-0.6-0.60.01.0-0.20.81.01.10.3-0.4-0.6
Bone: cortical tissue density1.41.95.7-1.7-2.12.12.02.0-1.5-2.42.40.6-1.2-0.9-1.0-0.50.0-0.7-0.20.31.10.30.0-0.1
Condit. Reinf. active minus inactive responses0.70.72.41.10.9-1.0-1.3-1.61.30.5-0.5-0.80.81.01.30.8-0.10.4-0.0-0.3-0.8-0.3-0.3-0.4
Condit. Reinf. active-inactive response ratio0.91.02.0-1.2-1.41.30.60.4-0.3-1.21.20.8-1.1-0.8-0.5-0.9-1.2-1.2-1.3-1.2-0.9-1.10.40.4
Condit. Reinf. active responses2.32.85.72.42.2-2.3-2.2-2.42.21.4-1.4-1.81.71.82.21.70.91.41.00.6-0.40.5-1.0-0.9
Condit. Reinf. inactive responses5.76.812.43.53.5-3.5-3.0-2.92.72.8-2.8-2.33.12.92.92.72.02.82.21.60.41.8-1.4-1.2
Incentive salience index mean3.23.98.22.62.2-2.4-2.8-2.82.91.7-1.7-1.62.12.32.82.10.81.71.00.5-0.50.6-1.4-1.3
Condit. Reinf. lever presses6.08.014.13.73.2-3.3-3.6-3.53.82.6-2.6-2.43.33.33.73.21.82.92.01.50.11.8-2.2-2.1
Condit. Reinf. active minus inactive responses0.30.30.90.60.3-0.3-0.3-0.30.6-0.30.3-0.90.2-0.10.60.70.90.30.80.70.50.4-0.8-0.9
Condit. Reinf. active-inactive response ratio0.10.10.4-0.0-0.20.20.20.20.1-0.20.2-0.4-0.4-0.7-0.3-0.10.4-0.20.40.20.30.0-0.3-0.6
Condit. Reinf. active responses0.60.81.71.10.8-0.7-0.6-0.50.90.2-0.2-1.20.60.30.91.01.30.71.31.20.80.8-1.2-1.2
Condit. Reinf. inactive responses1.41.72.91.71.5-1.4-1.0-0.91.10.7-0.7-1.51.51.21.41.61.51.51.51.40.91.2-1.2-1.0
Condit. Reinf. lever presses1.92.65.42.02.0-2.0-2.3-2.22.22.1-2.1-1.51.61.91.91.30.61.20.70.4-0.50.3-1.0-0.9
Condit. Reinf. lever reinforcers received0.81.11.91.41.1-1.0-0.9-0.81.10.5-0.5-1.30.90.61.11.21.41.01.41.20.70.9-1.3-1.3
Conditioned reinforcement - actives1.41.43.6-1.3-1.51.61.71.9-1.1-1.61.6-0.3-1.4-1.3-1.6-0.70.4-0.90.10.41.10.1-0.30.2
Conditioned reinforcement - inactives1.61.82.61.41.2-1.2-1.2-1.01.51.1-1.1-1.51.41.51.01.61.61.61.51.40.91.4-1.6-1.2
Conditioned locomotion0.10.10.4-0.10.00.0-0.2-0.00.30.5-0.5-0.4-0.2-0.0-0.6-0.3-0.0-0.2-0.2-0.2-0.1-0.2-0.20.1
Patch foraging indifference point 0 sec4.57.312.33.53.2-3.3-3.0-2.93.32.5-2.5-3.02.83.03.23.02.22.62.42.00.71.8-2.4-1.9
Patch foraging indifference point AUC1.92.25.1-1.6-1.41.51.71.7-1.7-1.11.11.1-2.3-2.1-2.2-1.9-0.9-2.0-1.0-0.8-0.1-1.21.00.9
Delay disc. indifference point, 0s delay0.50.62.00.20.3-0.4-1.1-1.20.80.8-0.80.90.20.20.6-0.2-1.0-0.2-0.8-1.0-1.4-0.90.20.0
Delay disc. indifference point, 16s delay0.40.41.40.71.1-1.1-0.7-0.70.21.2-1.20.10.60.7-0.20.2-0.00.50.1-0.1-0.30.10.30.4
Delay disc. indifference point, 2s delay1.51.74.4-1.0-0.80.7-0.2-0.2-0.20.2-0.21.8-1.1-1.1-1.1-1.6-2.0-1.6-1.8-2.1-1.9-2.01.00.8
Delay disc. indifference point, 24s delay0.00.00.3-0.10.1-0.00.10.2-0.20.2-0.20.3-0.2-0.1-0.6-0.3-0.1-0.2-0.0-0.2-0.0-0.10.20.1
Delay disc. indifference point, 4s delay0.50.51.3-0.6-0.40.40.10.1-0.20.0-0.00.6-0.8-0.8-0.8-1.0-0.9-0.9-1.0-1.0-0.9-1.10.60.7
Delay disc. indifference point, 8s delay1.01.11.91.21.4-1.3-1.0-0.90.91.3-1.3-1.11.21.20.71.01.01.21.00.90.40.9-0.7-0.3
Indifference point function ln k2.12.97.31.81.5-1.6-1.9-1.82.01.4-1.4-1.02.52.52.72.11.02.31.11.00.31.5-1.3-0.9
Indifference point function log k2.12.97.31.81.5-1.6-1.9-1.82.01.4-1.4-1.02.52.52.72.11.02.31.11.00.31.5-1.3-0.9
Patch foraging total patch changes 0 sec4.57.212.53.53.3-3.3-3.0-2.83.12.5-2.5-3.02.93.13.32.92.22.62.42.00.61.8-2.2-1.8
Patch foraging total patch changes 12 sec1.11.43.81.82.0-1.9-1.4-1.41.31.5-1.5-1.70.80.81.10.90.80.60.80.8-0.10.2-0.6-0.4
Patch foraging total patch changes 18 sec0.70.92.71.01.0-0.9-0.2-0.10.30.2-0.2-1.60.40.80.51.01.40.71.31.41.11.1-0.7-0.9
Patch foraging total patch changes 24 sec1.82.25.22.22.3-2.2-1.7-1.71.41.7-1.7-1.61.41.60.91.41.11.31.30.90.10.8-0.7-1.0
Patch foraging total patch changes 6 sec1.62.45.11.61.2-1.2-0.5-0.41.10.2-0.2-1.91.21.51.41.92.21.52.32.21.81.8-1.9-1.8
Patch foraging time to switch 0 sec0.00.00.2-0.1-0.10.1-0.2-0.30.10.1-0.1-0.10.10.3-0.00.0-0.40.0-0.5-0.4-0.4-0.10.1-0.1
Patch foraging water rate 0 sec1.11.83.41.71.8-1.8-1.1-1.00.91.3-1.3-1.01.71.51.61.41.31.61.51.30.71.2-0.6-0.6
Patch foraging water rate 12 sec0.10.10.8-0.0-0.20.10.1-0.10.1-0.50.5-0.00.20.40.90.4-0.00.10.00.20.00.0-0.1-0.0
Patch foraging water rate 18 sec0.10.20.5-0.2-0.40.40.50.6-0.3-0.50.5-0.10.20.10.40.30.50.40.40.60.70.6-0.2-0.2
Patch foraging water rate 24 sec0.71.03.20.50.3-0.20.80.7-0.6-0.80.8-1.00.50.30.81.11.61.01.61.71.81.5-0.7-0.8
Patch foraging water rate 6 sec0.10.21.00.10.5-0.5-0.0-0.3-0.40.3-0.30.60.40.50.3-0.1-0.30.3-0.2-0.2-0.4-0.11.00.6
Seeking ratio, delayed vs. immediate footshock0.30.30.8-0.3-0.90.7-0.4-0.40.8-0.70.70.1-0.3-0.20.70.1-0.6-0.5-0.5-0.5-0.6-0.6-0.6-0.6
Distance traveled before self-admin1.11.23.5-0.60.0-0.0-0.2-0.5-0.60.5-0.51.1-0.5-0.4-0.7-1.3-1.7-0.9-1.6-1.8-1.9-1.51.91.1
Distance traveled after self-admin3.33.65.6-2.4-2.22.21.91.8-2.0-1.41.42.1-2.0-2.1-2.4-2.3-1.8-2.0-1.9-1.8-0.8-1.71.71.5
Extensor digitorum longus weight4.116.029.8-4.1-2.72.62.51.7-4.2-1.61.65.1-3.4-3.0-4.1-4.9-5.1-4.1-5.0-4.9-4.1-4.45.45.5
Bone: elastic displacement0.50.51.50.91.2-1.2-0.9-1.20.50.7-0.70.00.80.60.60.3-0.20.4-0.1-0.3-0.9-0.40.50.7
Bone: elastic work1.51.95.21.62.3-2.3-1.9-2.11.02.3-2.30.21.31.10.50.4-0.30.70.0-0.5-1.4-0.70.70.5
Bone: endosteal estimation0.20.51.6-0.30.0-0.0-0.4-0.20.10.9-0.91.2-0.5-0.8-0.6-1.0-0.8-0.8-0.7-0.9-0.9-1.20.50.5
Bone: endosteal perimeter0.40.82.5-0.6-0.30.3-0.3-0.20.10.5-0.51.2-1.0-1.2-0.6-1.2-1.1-1.3-1.1-1.2-1.2-1.60.50.7
Epididymis fat weight1.22.97.11.60.9-0.9-1.3-0.92.20.6-0.6-2.21.31.42.02.11.91.61.91.81.51.6-2.6-2.7
Delta time in closed arm before/after self-admin0.10.10.4-0.2-0.40.3-0.4-0.10.70.4-0.40.5-0.2-0.20.0-0.3-0.4-0.4-0.4-0.4-0.3-0.5-0.5-0.3
Delta time in open arm before/after self-admin0.10.10.70.20.1-0.1-0.00.10.10.0-0.0-0.9-0.1-0.10.10.20.30.00.30.30.30.3-0.3-0.3
Diff in mean of infusions in LGA sessions0.60.73.6-0.30.1-0.11.20.6-1.9-1.11.10.4-0.1-0.3-0.8-0.3-0.0-0.1-0.10.00.10.11.81.2
Delay discount exponential model param0.40.51.9-0.7-1.01.01.00.9-0.7-1.41.40.3-0.5-0.50.0-0.1-0.0-0.3-0.10.10.40.20.1-0.1
Extinction: sum of active levers before priming1.11.12.31.11.2-1.1-0.3-0.30.20.6-0.6-1.11.21.10.71.21.41.41.41.41.21.5-0.6-1.1
Active lever presses in extinction session 60.70.71.90.60.4-0.40.20.20.0-0.30.2-1.10.50.60.40.91.40.91.31.41.31.2-0.8-1.0
Bone: final force0.71.22.21.41.2-1.2-1.1-0.81.01.3-1.3-1.01.20.90.61.01.21.11.31.00.60.8-0.9-1.5
Bone: final moment0.71.22.21.51.4-1.4-1.3-1.21.11.4-1.4-0.91.21.00.60.90.91.11.00.70.20.4-0.8-1.3
Food consumed during 24 hour testing period0.50.52.20.90.9-0.9-1.0-0.90.91.3-1.3-1.50.50.30.30.10.10.30.0-0.1-0.4-0.1-0.3-0.2
Glucose0.50.82.7-0.7-0.30.61.51.7-1.6-0.40.4-0.6-1.1-1.0-1.6-0.80.6-0.60.30.61.20.30.40.2
Heart weight0.10.10.50.2-0.10.0-0.4-0.30.50.3-0.3-0.0-0.2-0.20.1-0.1-0.2-0.4-0.2-0.3-0.3-0.6-0.3-0.7
Delay discount hyperbolic model param0.40.41.5-0.4-0.80.70.90.8-0.5-1.21.2-0.1-0.1-0.20.30.30.40.10.40.60.80.6-0.3-0.4
Intermittent access intake day 1-15 change2.12.04.01.41.0-1.0-0.8-0.71.20.4-0.4-1.41.51.61.62.01.71.81.81.71.41.9-1.6-1.5
Intermittent access intake escalation1.81.83.71.31.0-1.0-0.5-0.40.70.2-0.2-1.51.41.51.41.81.71.81.71.71.51.9-1.3-1.2
Intermittent access intake escalation 20.40.31.20.3-0.10.1-0.10.00.4-0.30.3-1.10.30.40.80.80.70.50.60.70.80.8-0.9-0.8
Intermitt. access day 1 inactive lever presses0.90.92.11.10.7-0.8-0.4-0.60.6-0.20.2-1.41.00.91.21.41.21.11.21.20.81.1-0.9-0.9
Intermitt. access day 15 inactive lever presses1.21.32.71.31.2-1.2-1.1-1.11.10.7-0.7-1.61.31.31.61.41.11.31.11.10.41.0-0.9-0.9
Intermitt. access escalation Index0.30.21.1-0.30.0-0.00.40.2-0.8-0.00.00.6-0.3-0.2-0.5-0.5-0.5-0.3-0.4-0.5-0.4-0.31.10.8
Intermittent access day 1 total infusions1.72.03.61.61.9-1.7-0.7-0.60.61.2-1.2-1.91.51.50.61.41.91.71.81.71.21.6-0.8-0.7
Intermittent access day 15 total infusions2.32.65.01.71.6-1.5-0.7-0.60.90.6-0.6-2.21.61.61.22.02.22.02.22.11.72.1-1.5-1.4
Intermittent access terminal intake (last 3 days)1.21.33.01.11.0-0.9-0.2-0.10.40.4-0.4-1.71.01.00.51.31.71.41.61.61.41.6-1.0-0.9
Intermittent access total infusions2.52.85.81.71.7-1.6-0.6-0.40.70.8-0.8-2.21.71.81.01.92.42.12.32.21.92.3-1.4-1.3
Intermittent access day 1 locomotion3.23.45.12.12.2-2.1-1.4-1.21.51.5-1.5-2.02.22.11.42.12.12.32.21.91.32.0-1.5-1.4
Intermittent access day 15 total locomotion1.01.03.30.80.6-0.5-0.00.20.4-0.00.0-1.80.60.60.21.11.71.01.51.61.51.3-1.2-1.1
Intermittent access total locomotion2.32.75.31.81.8-1.7-1.0-0.91.11.2-1.2-2.31.71.81.21.82.11.92.01.81.31.8-1.4-1.4
Intermittent access standard deviation1.01.12.11.31.4-1.4-0.4-0.60.10.4-0.4-1.41.11.10.91.21.41.31.31.20.81.2-0.2-0.4
Left kidney weight1.74.89.12.62.1-2.2-2.8-2.53.02.4-2.4-1.72.62.42.82.41.42.41.51.20.31.3-2.0-1.8
Right kidney weight3.18.619.73.32.6-2.8-4.1-3.64.43.4-3.4-1.93.43.34.03.11.33.01.61.2-0.01.5-2.8-2.5
Cocaine induced anxiety1.31.56.10.20.6-0.7-1.4-1.70.91.1-1.11.00.30.40.3-0.6-1.9-0.5-1.6-1.9-2.5-1.61.21.0
Post-drug Anxiety0.30.31.40.4-0.1-0.0-0.8-0.81.2-0.10.1-0.20.30.51.20.7-0.20.1-0.1-0.1-0.40.0-0.8-0.6
Baseline Anxiety1.71.84.21.00.5-0.4-0.10.20.6-0.20.1-1.50.90.91.41.62.01.42.02.02.01.9-1.7-1.6
Tail length1.23.55.22.22.0-2.0-2.2-1.82.32.1-2.1-2.01.91.92.12.01.51.91.51.50.61.3-1.7-1.7
Length with tail0.62.14.62.01.8-1.9-1.9-2.11.81.3-1.3-1.01.91.72.01.60.41.70.60.3-0.50.7-0.5-0.1
Length without tail0.40.83.60.10.2-0.3-0.4-1.00.0-0.10.11.20.4-0.00.3-0.2-1.3-0.1-1.1-1.4-1.6-0.81.21.9
Times rat made contact with spout2.73.18.71.71.5-1.4-0.6-0.20.90.9-0.9-2.91.51.71.01.92.51.92.32.52.22.1-1.8-1.9
Lifetime Intake2.12.44.61.61.7-1.6-0.6-0.50.71.0-1.0-2.01.61.70.81.72.11.92.12.01.62.1-1.2-1.1
Liver weight, left0.20.31.00.1-0.10.00.1-0.2-0.3-0.70.70.3-0.4-0.8-0.3-0.5-0.4-0.7-0.5-0.6-0.8-1.00.50.6
Liver weight, right0.10.10.7-0.00.4-0.30.40.2-0.80.1-0.10.40.1-0.1-0.6-0.30.10.10.10.0-0.00.00.80.8
Locomotor activity2.74.313.20.91.8-2.0-2.4-2.91.02.5-2.51.81.11.00.2-0.7-2.5-0.1-2.3-2.5-3.6-2.32.22.5
Locomotor testing distance2.23.610.01.72.4-2.6-2.8-3.21.62.7-2.70.81.81.81.00.5-1.40.7-1.1-1.4-2.6-1.21.11.4
Locomotor testing rearing2.84.412.82.32.8-3.0-3.2-3.62.12.9-2.90.32.02.01.50.8-1.30.9-0.8-1.3-2.6-1.10.70.9
Locomotion in novel chamber1.21.54.61.41.9-1.9-1.4-1.40.62.1-2.1-0.21.61.60.70.70.31.30.50.1-0.30.60.30.2
Locomotion in novel chamber post-restriction0.30.41.8-0.8-0.50.60.60.7-0.8-0.10.10.1-0.7-0.8-1.3-0.9-0.2-0.8-0.5-0.3-0.1-0.60.40.0
Fecal boli incidents, locomotor time 11.21.34.31.22.1-2.0-1.1-1.30.11.9-1.9-0.61.21.30.40.40.21.00.30.2-0.40.50.91.1
Change in fecal boli incidents, locomotor task1.61.53.6-1.4-1.91.81.00.9-0.5-1.81.80.2-1.6-1.4-0.3-1.0-1.1-1.6-1.3-1.1-0.7-1.20.20.2
Time >=10cm from walls, locomotor time 10.70.71.60.90.9-0.9-1.2-1.11.31.0-1.0-0.11.01.11.31.00.20.90.40.4-0.10.6-0.7-0.2
Bouts of movement, locomotor time 10.90.94.1-1.1-1.11.01.10.9-1.2-1.21.22.0-0.7-0.6-0.8-0.7-0.8-0.6-0.8-0.7-0.1-0.30.80.9
Total resting periods, locomotor time 11.11.23.0-1.3-1.31.21.41.2-1.4-1.41.41.7-1.0-0.9-1.0-0.9-0.9-0.9-0.9-0.8-0.1-0.50.91.1
Rest time, locomotor task time 11.51.73.8-1.4-0.80.80.80.6-1.3-0.30.31.9-1.0-1.0-1.3-1.6-1.7-1.2-1.6-1.7-1.2-1.41.62.0
Distance moved, locomotor task time 10.70.82.40.80.1-0.2-0.3-0.11.0-0.50.5-1.00.40.30.91.11.20.61.21.31.10.9-1.5-1.5
Vertical activity count, locomotor time 10.10.10.6-0.00.1-0.1-0.2-0.40.00.00.00.3-0.0-0.0-0.2-0.2-0.7-0.2-0.6-0.7-0.8-0.50.60.5
Time >=10cm from walls, locomotor time 21.11.23.1-1.0-0.70.60.2-0.0-0.6-0.20.20.9-0.8-0.7-0.9-1.2-1.7-1.1-1.6-1.8-1.5-1.31.41.5
Bouts of movement, locomotor time 20.80.92.9-0.9-0.60.61.41.1-1.7-1.11.10.9-0.8-0.8-1.3-0.9-0.5-0.7-0.5-0.40.0-0.41.31.2
Total resting periods, locomotor time 20.60.62.6-0.7-0.30.41.21.0-1.6-0.80.80.8-0.5-0.5-1.1-0.7-0.3-0.4-0.3-0.20.2-0.21.31.2
Rest time, locomotor task time 20.30.31.5-0.20.4-0.20.70.6-1.20.1-0.10.50.20.0-0.8-0.40.30.20.30.30.40.31.01.0
Distance moved, locomotor task time 20.60.71.91.10.7-0.8-1.1-1.11.40.4-0.4-0.80.70.71.31.10.40.70.60.40.10.4-1.0-1.0
Vertical activity count, locomotor time 20.80.92.8-0.5-0.20.1-0.1-0.4-0.40.2-0.20.9-0.6-0.5-0.6-1.0-1.6-0.9-1.4-1.7-1.5-1.31.31.3
Light reinforcement 11.52.86.71.10.6-0.5-0.20.30.90.2-0.2-2.61.21.20.81.92.61.72.32.62.52.3-2.2-2.2
Light reinforcement 21.41.96.8-0.8-1.41.51.62.0-0.6-1.41.3-1.1-0.2-0.4-0.70.61.70.61.31.82.61.8-1.5-1.5
Bone: marrow area0.20.51.4-0.10.1-0.1-0.5-0.30.21.0-1.01.1-0.4-0.7-0.5-0.9-0.8-0.6-0.6-0.8-0.9-1.20.40.4
Bone: maximum diameter0.61.03.2-1.1-0.90.90.91.0-0.9-0.40.41.0-1.6-1.8-1.1-1.4-0.7-1.5-0.7-0.6-0.3-1.20.60.6
Bone: maximum force0.50.82.81.21.4-1.3-1.2-1.00.71.7-1.7-0.40.90.50.30.30.50.60.60.3-0.1-0.1-0.1-0.7
Bone: maximum moment0.61.13.51.41.6-1.6-1.5-1.40.91.9-1.9-0.41.00.60.40.30.30.60.50.0-0.5-0.4-0.1-0.6
Mean time between licks in bursts0.10.10.7-0.0-0.20.2-0.10.10.30.0-0.0-0.7-0.4-0.00.10.00.4-0.40.20.20.2-0.3-0.6-0.8
Mean num. licks in bursts0.10.10.40.30.3-0.3-0.3-0.20.20.5-0.5-0.70.3-0.0-0.10.10.30.30.20.20.10.3-0.2-0.4
Cd content in liver0.20.20.60.0-0.10.10.40.4-0.1-0.60.6-0.6-0.10.20.50.50.70.20.60.80.80.7-0.4-0.6
Co content in liver4.14.89.3-2.9-2.32.42.82.7-3.0-1.81.81.8-2.6-2.1-3.0-2.5-1.5-2.3-1.8-1.3-0.3-1.21.91.9
Cu content in liver1.21.52.5-1.3-1.01.01.20.8-1.4-1.21.20.4-1.5-1.4-1.0-1.4-1.1-1.6-1.2-1.2-0.9-1.31.41.5
Fe content in liver0.10.20.80.3-0.10.1-0.2-0.10.6-0.30.3-0.2-0.00.00.70.50.50.00.50.40.40.2-0.9-0.5
K content in liver0.50.51.40.30.1-0.0-0.20.20.60.3-0.30.40.60.60.60.81.00.81.11.01.11.0-1.2-0.8
Mg content in liver0.20.20.6-0.5-0.50.50.50.7-0.3-0.10.10.8-0.4-0.3-0.3-0.20.3-0.20.30.20.60.0-0.30.1
Mn content in liver0.10.20.6-0.7-0.60.60.50.8-0.30.2-0.20.6-0.5-0.3-0.1-0.40.0-0.3-0.00.10.50.1-0.2-0.0
Na content in liver2.52.77.01.21.7-1.9-2.5-2.71.72.5-2.50.61.11.31.30.1-1.40.2-1.1-1.4-2.4-1.40.70.6
Rb content in liver0.30.41.0-0.1-0.50.50.50.5-0.1-0.90.9-0.30.10.41.00.60.70.40.70.70.90.8-0.6-0.6
Se content in liver1.11.45.70.10.5-0.6-1.2-1.50.50.9-0.91.50.0-0.00.4-0.8-1.7-0.7-1.4-1.9-2.4-1.71.21.1
Sr content in liver0.40.31.3-0.3-0.10.1-0.0-0.0-0.20.0-0.0-0.6-0.7-0.7-1.1-0.7-0.5-0.9-0.7-0.7-0.7-1.00.50.5
Zn content in liver1.11.23.70.61.1-1.1-1.4-1.70.81.4-1.4-0.10.70.5-0.2-0.3-1.10.1-0.9-1.5-1.9-1.11.01.1
Bone: minimum diameter0.30.51.80.81.0-1.0-1.0-0.90.61.3-1.30.10.1-0.3-0.0-0.3-0.3-0.2-0.1-0.5-0.8-0.90.20.2
Time in familiar zone, hab. session 10.90.82.10.60.4-0.4-0.3-0.00.60.5-0.5-1.20.81.10.60.91.21.11.01.21.01.3-1.0-1.4
Time in novel zone, hab. session 14.64.47.0-2.1-1.91.92.11.7-2.4-2.22.21.8-2.6-2.6-2.3-2.3-1.8-2.6-1.9-1.7-1.0-2.22.02.3
Total zone transitions, hab. session 10.30.41.30.20.5-0.5-0.4-0.6-0.00.5-0.50.6-0.2-0.5-0.2-0.7-0.7-0.5-0.6-0.9-1.2-1.00.80.9
Total locomotion distance, hab. session 10.50.82.21.01.2-1.2-1.3-1.50.91.0-1.0-0.10.2-0.20.6-0.2-0.5-0.3-0.4-0.8-1.4-1.20.30.5
Locomotion velocity, hab. session 11.52.15.81.82.1-2.2-2.3-2.41.72.2-2.2-0.21.20.91.30.5-0.30.6-0.1-0.6-1.6-0.70.20.4
Time in familiar zone, hab. session 21.01.02.4-1.5-1.31.31.41.4-1.6-0.90.91.1-0.6-0.8-1.2-1.0-0.8-0.5-0.9-0.60.1-0.21.01.0
Time in novel zone, hab. session 20.20.20.60.70.8-0.8-0.5-0.60.40.3-0.3-0.6-0.3-0.10.10.00.2-0.50.20.1-0.4-0.5-0.0-0.1
Total zone transitions, hab. session 20.91.24.00.51.1-1.2-1.1-1.50.21.0-1.00.30.30.40.4-0.5-1.3-0.4-1.2-1.4-2.0-1.21.51.7
Total locomotion distance, hab. session 20.60.82.30.81.2-1.3-1.0-1.40.30.8-0.8-0.40.20.20.5-0.2-0.8-0.3-0.7-0.9-1.5-1.11.01.1
Locomotion velocity, hab. session 20.91.23.60.81.4-1.4-1.2-1.60.41.2-1.2-0.10.30.20.4-0.4-1.1-0.4-0.9-1.2-1.9-1.31.31.4
Novel to familiar place preference ratio1.41.43.61.91.9-1.8-1.1-1.20.90.8-0.8-1.50.70.91.21.21.40.71.51.30.40.4-0.7-0.9
Novelty place preference1.61.73.92.02.0-1.9-1.2-1.31.00.8-0.8-1.60.91.11.31.41.50.81.61.40.50.5-0.7-1.0
Time in novel zone, NPP test1.21.23.21.71.8-1.7-1.0-1.10.80.7-0.7-1.50.60.91.01.11.30.51.41.20.30.2-0.5-0.8
Total zone transitions, NPP test0.71.02.81.41.7-1.7-1.3-1.40.81.3-1.3-0.90.91.11.00.60.10.60.2-0.0-0.60.10.20.5
Total locomotion distance, NPP test1.52.05.12.02.3-2.2-1.7-1.81.41.7-1.7-1.61.51.41.51.20.81.20.90.6-0.20.5-0.5-0.2
Locomotion velocity, NPP test1.82.55.62.32.4-2.3-1.8-1.91.61.7-1.7-1.71.81.71.81.51.01.51.20.8-0.00.9-0.7-0.5
Intraocular pressure0.71.04.21.31.2-1.1-0.3-0.40.40.1-0.1-2.00.60.20.61.11.50.71.51.51.00.8-0.7-1.3
Delta distance traveled before/after self-admin2.62.86.2-2.0-2.32.32.42.5-2.0-2.22.21.1-1.8-2.0-2.0-1.4-0.4-1.4-0.6-0.20.8-0.40.50.8
Delta ambulatory time before/after self-admin1.21.43.1-1.4-1.61.61.71.8-1.4-1.51.50.7-1.1-1.3-1.5-1.0-0.3-0.9-0.4-0.20.6-0.30.40.8
Parametrial fat weight0.51.13.20.1-0.60.60.60.90.2-0.90.9-1.1-0.2-0.10.20.81.50.41.31.61.81.2-1.5-1.8
Pavlov. Cond. lever latency3.34.26.5-2.4-2.12.22.12.0-2.3-1.61.61.9-2.5-2.5-2.5-2.5-1.8-2.4-1.9-1.6-0.8-1.91.81.8
Pavlov. Cond. magazine entry latency0.91.12.31.00.7-0.7-0.7-0.61.00.4-0.4-1.51.20.91.11.41.31.41.21.10.91.3-1.2-1.1
Pavlov. Cond. change in total contacts1.71.83.61.91.8-1.8-1.5-1.61.51.1-1.1-1.31.71.41.71.51.01.51.20.70.10.9-0.8-0.6
Pavlov. Cond. index score3.13.96.32.32.0-2.0-1.9-1.82.11.5-1.5-2.22.52.32.42.41.82.51.81.50.91.9-1.7-1.7
Pavlov. Cond. latency score3.64.66.82.52.1-2.2-2.1-1.92.41.6-1.6-2.42.62.42.62.62.02.62.11.81.02.0-1.9-2.0
Pavlov. Cond. lever contacts3.64.26.92.42.1-2.1-2.1-2.02.31.6-1.6-1.72.62.52.62.51.72.61.91.60.82.0-1.7-1.8
Pavlov. Cond. magazine entry number0.40.50.9-0.8-0.70.70.50.5-0.6-0.50.51.0-0.9-0.6-0.7-0.8-0.7-0.9-0.7-0.6-0.5-0.80.50.5
Pavlov. Cond. intertrial magazine entries1.21.53.21.51.3-1.4-1.7-1.71.81.3-1.30.01.51.61.71.30.31.20.70.3-0.40.5-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.2.63.35.72.11.9-1.9-1.8-1.71.91.6-1.6-1.92.42.12.12.11.52.31.61.30.71.7-1.4-1.4
Pavlov. Cond. response bias0.91.12.41.10.9-0.9-1.0-0.91.20.8-0.8-0.91.61.31.41.30.91.50.90.70.51.2-1.0-0.9
Pavlov. Cond. lever latency1.11.43.5-1.2-1.51.51.91.8-1.5-1.81.80.7-1.2-1.5-1.3-0.50.3-0.70.20.41.10.40.10.1
Pavlov. Cond. magazine entry latency1.92.26.41.41.8-1.8-2.1-1.91.62.5-2.5-0.01.92.21.40.8-0.11.40.1-0.3-0.70.5-0.3-0.1
Pavlov. Cond. change in total contacts0.81.24.2-0.6-0.20.0-0.6-0.80.10.6-0.61.5-0.3-0.1-0.1-1.1-1.7-0.8-1.6-1.8-2.0-1.51.21.3
Pavlov. Cond. index score1.41.85.11.11.5-1.6-2.0-2.01.42.3-2.30.21.51.81.20.3-0.70.9-0.5-0.9-1.5-0.40.30.5
Pavlov. Cond. latency score1.62.05.11.11.5-1.6-2.2-2.11.62.3-2.30.21.51.91.40.4-0.70.9-0.6-0.9-1.6-0.40.20.3
Pavlov. Cond. lever contacts1.62.25.51.51.9-2.0-2.3-2.31.72.3-2.3-0.41.41.71.40.5-0.50.7-0.4-0.7-1.6-0.60.20.4
Pavlov. Cond. magazine entry number1.11.44.3-1.1-1.31.31.71.4-1.5-2.12.10.2-1.4-1.7-1.1-0.6-0.1-1.1-0.20.10.5-0.40.50.3
Pavlov. Cond. intertrial magazine entries2.63.57.61.91.3-1.2-0.6-0.21.40.5-0.5-2.61.20.81.42.12.71.72.72.82.42.0-2.5-2.7
Pavlov. Cond. lever-magazine prob. diff.1.11.44.20.81.2-1.3-1.8-1.81.32.0-2.00.31.21.61.00.1-0.80.6-0.6-0.9-1.5-0.50.30.5
Pavlov. Cond. response bias1.92.57.21.52.1-2.2-2.4-2.41.62.7-2.70.01.51.91.30.4-0.60.8-0.4-0.8-1.7-0.60.40.6
Time in closed arm before self-admin0.10.20.6-0.7-0.80.80.20.4-0.0-0.30.30.5-0.4-0.5-0.3-0.4-0.3-0.4-0.4-0.3-0.0-0.2-0.10.2
Time in closed arm after self-admin0.20.20.5-0.6-0.60.60.10.2-0.1-0.20.20.7-0.3-0.4-0.3-0.5-0.6-0.5-0.6-0.6-0.4-0.50.20.3
Time in open arm before self-admin0.40.41.1-0.4-0.10.20.70.4-1.0-0.40.40.9-0.4-0.6-0.9-0.8-0.6-0.6-0.6-0.5-0.4-0.61.01.1
Time in open arm after self-admin0.10.10.2-0.3-0.20.30.30.3-0.3-0.00.0-0.0-0.5-0.4-0.4-0.4-0.3-0.4-0.3-0.3-0.1-0.30.20.5
Bone: periosteal estimation0.20.41.2-0.20.00.1-0.20.0-0.00.8-0.81.0-0.6-1.0-0.8-0.9-0.5-0.8-0.4-0.6-0.6-1.10.30.3
Bone: periosteal perimeter0.20.31.4-0.3-0.20.30.10.3-0.20.2-0.20.6-0.9-1.2-0.6-0.9-0.4-1.0-0.4-0.5-0.4-1.00.20.3
Bone: post-yield work0.40.51.80.20.10.00.30.6-0.10.2-0.2-0.80.1-0.1-0.20.31.20.51.11.11.40.9-0.8-1.4
Progressive ratio test 1 active lever presses0.70.72.30.40.6-0.40.70.7-0.6-0.20.2-1.50.30.3-0.50.51.50.71.31.41.51.2-0.3-0.2
Progressive ratio test 1 breakpoint0.70.82.60.20.3-0.20.90.9-0.7-0.40.4-1.50.10.1-0.50.51.50.61.31.41.61.2-0.4-0.2
Progressive ratio test 1 inactive lever presses3.63.98.71.91.5-1.4-0.2-0.20.6-0.10.0-2.81.71.71.62.53.02.22.82.92.52.8-1.8-2.1
Progressive ratio test 2 active lever presses1.41.55.80.30.2-0.01.01.3-0.5-0.50.5-1.80.20.2-0.40.82.10.91.82.12.41.8-1.2-1.1
Progressive ratio test 2 breakpoint1.61.85.50.80.7-0.50.50.8-0.00.0-0.0-1.90.60.70.01.12.31.32.12.32.42.0-1.4-1.2
Progressive ratio test 2 inactive lever presses1.92.26.31.51.4-1.3-0.6-0.50.80.7-0.7-2.51.41.41.11.62.01.71.91.91.51.8-1.3-1.2
Incentive Sensitization - Responses1.01.03.10.50.3-0.20.10.50.40.3-0.3-1.20.40.50.10.81.50.91.41.61.81.5-1.5-1.3
Incentive Sensitization - Breakpoint1.31.33.30.70.5-0.4-0.10.30.70.5-0.5-1.40.60.70.31.11.71.11.51.81.81.7-1.8-1.5
Sum of active levers in priming session hrs 5-62.92.85.7-2.0-2.12.22.42.4-2.0-2.22.21.1-2.0-2.0-2.1-1.5-0.5-1.6-0.7-0.20.7-0.50.60.7
Progressive ratio0.50.62.0-0.7-0.30.51.41.3-1.4-0.80.80.4-0.3-0.2-0.8-0.20.40.20.50.51.10.80.60.6
Food seeking constrained by brief footshock5.36.515.9-3.1-2.72.83.83.3-4.0-3.33.32.2-2.5-2.5-2.7-2.3-1.1-2.0-1.4-0.80.4-0.72.62.4
Seeking ratio, punishment vs. effort0.91.12.2-1.2-1.51.40.70.6-0.6-1.11.10.7-1.3-1.3-0.7-1.1-1.0-1.5-1.3-1.0-0.8-1.30.50.4
Retroperitoneal fat weight0.20.82.40.5-0.20.2-0.00.20.7-0.60.6-0.40.60.40.81.21.21.01.41.01.31.1-1.6-1.4
Reaction time number correct1.82.55.0-2.0-1.92.02.22.1-2.1-2.02.01.6-1.8-1.9-1.5-1.5-0.6-1.6-0.7-0.50.3-0.81.10.8
Reaction time mean minus median0.91.24.01.11.4-1.5-1.6-2.01.01.3-1.30.30.70.40.20.2-1.10.2-0.8-1.2-1.8-0.90.81.1
Reaction time mean minus median AUC0.40.51.60.91.0-1.0-1.1-1.30.71.0-1.00.00.50.2-0.20.2-0.50.3-0.3-0.6-0.9-0.40.30.5
Reaction time num false alarms0.10.10.30.10.2-0.1-0.3-0.10.40.4-0.40.1-0.2-0.2-0.5-0.3-0.1-0.3-0.0-0.2-0.1-0.4-0.50.2
Reaction time num false alarms AUC0.10.10.70.20.1-0.0-0.30.00.60.5-0.4-0.1-0.2-0.2-0.6-0.20.1-0.20.10.00.1-0.3-0.9-0.2
Reaction time trials correct on left1.82.55.0-2.0-1.92.02.22.1-2.1-2.02.01.6-1.8-1.9-1.5-1.5-0.6-1.6-0.7-0.50.3-0.81.10.8
Reaction time trials on left1.72.44.9-2.0-1.92.02.22.1-2.0-2.02.01.6-1.8-1.9-1.5-1.5-0.6-1.5-0.7-0.50.3-0.71.00.7
Reaction time mean0.71.03.40.40.4-0.6-1.3-1.51.01.0-1.00.90.2-0.10.3-0.3-1.4-0.3-1.2-1.5-1.8-1.20.50.9
Reaction time mean AUC0.91.24.50.20.4-0.5-1.3-1.50.81.0-1.01.20.1-0.20.2-0.5-1.7-0.5-1.4-1.7-2.1-1.40.81.1
Median of all reaction times0.50.62.2-0.0-0.1-0.1-1.0-1.00.80.7-0.70.9-0.0-0.30.4-0.4-1.3-0.4-1.1-1.3-1.5-1.10.20.6
Reaction time omissions0.20.31.01.00.5-0.6-0.8-0.91.00.2-0.2-0.30.2-0.00.30.60.30.10.50.2-0.2-0.1-0.7-0.6
Reaction time false alarm rate0.60.81.81.11.1-1.0-1.1-0.81.31.2-1.2-1.00.80.80.20.70.60.70.70.50.30.4-1.3-0.6
Reaction time premature initiation rate0.70.93.8-1.2-1.61.51.31.2-0.8-2.02.00.3-0.9-0.7-0.4-0.1-0.1-0.6-0.30.20.50.1-0.1-0.1
Reaction time premature initiations2.13.08.6-2.2-2.62.52.42.3-1.9-2.92.91.1-1.9-1.8-1.2-1.0-0.4-1.5-0.7-0.20.7-0.30.40.4
Std. dev. reaction times0.60.93.20.60.7-0.8-1.2-1.50.70.8-0.80.50.1-0.2-0.0-0.3-1.3-0.4-1.0-1.4-1.8-1.20.81.1
Reaction time trials completed1.72.44.9-2.0-1.92.02.22.1-2.0-2.02.01.6-1.8-1.9-1.5-1.5-0.6-1.5-0.7-0.50.3-0.71.00.7
Reaction time trials AUC1.82.65.1-2.1-2.02.02.22.1-2.1-2.02.01.6-1.8-1.9-1.5-1.6-0.6-1.6-0.8-0.50.3-0.81.10.8
Run reversals in cocaine runway, females0.10.10.5-0.2-0.30.40.30.60.10.2-0.20.0-0.2-0.1-0.6-0.10.40.20.40.40.70.5-0.5-0.5
Run reversals in cocaine runway, males1.01.03.51.01.9-1.8-0.8-1.0-0.11.6-1.7-0.11.11.10.10.20.10.80.30.0-0.50.31.01.0
Latency to leave start box in cocaine runway1.31.42.7-1.2-0.90.80.60.3-1.0-0.70.71.2-1.3-1.0-1.0-1.4-1.6-1.5-1.6-1.5-1.4-1.61.51.3
Latency to leave start box in cocaine runway, F0.50.61.4-0.5-0.30.20.3-0.0-0.8-0.50.50.6-0.7-0.5-0.7-0.8-0.9-0.9-0.9-0.9-1.0-1.01.21.0
Latency to leave start box in cocaine runway, M0.10.10.3-0.2-0.10.1-0.1-0.10.00.3-0.30.50.00.0-0.0-0.3-0.4-0.1-0.4-0.3-0.4-0.30.30.2
Std. dev. time between licks in bursts1.21.54.91.51.1-1.2-2.0-1.92.21.2-1.2-1.70.60.71.60.80.30.10.3-0.0-0.8-0.6-1.2-1.3
Total sessions with >9 infusions0.30.30.70.30.2-0.10.00.20.30.0-0.1-0.80.30.30.20.50.80.50.70.80.80.8-0.9-0.9
Short access day 1 total inactive lever presses4.45.08.72.72.9-2.8-1.5-1.41.32.0-2.0-2.22.62.51.52.42.72.72.82.51.72.5-1.4-1.3
Short access day 10 total inactive lever presses0.80.91.90.90.6-0.6-0.3-0.20.4-0.00.0-1.40.81.01.01.31.21.01.21.31.11.4-1.0-1.1
Short access day 1 total infusions0.30.30.90.50.5-0.40.20.3-0.20.1-0.1-0.70.40.4-0.00.50.90.50.90.90.90.9-0.4-0.2
Short access day 10 total infusions2.02.36.11.82.5-2.4-1.4-1.50.82.0-2.0-1.51.81.90.51.21.21.71.31.00.21.1-0.1-0.4
Short access total infusions1.92.13.61.61.7-1.6-0.8-0.70.81.1-1.1-1.71.61.70.91.61.91.81.91.81.31.9-1.1-1.1
Short access day 1 locomotion0.50.61.60.70.9-0.9-1.2-1.20.91.1-1.1-0.20.80.90.90.3-0.30.4-0.2-0.4-0.9-0.10.1-0.0
Short access day 10 total locomotion0.70.82.00.90.9-0.9-1.3-1.11.41.4-1.4-0.40.91.10.80.60.30.70.40.1-0.30.3-0.8-0.8
Short access total locomotion1.92.03.51.61.5-1.5-1.7-1.51.91.4-1.4-1.31.61.71.71.51.01.51.10.80.21.0-1.3-1.3
One hour access (0.3 mA shock)0.81.02.11.11.5-1.3-0.3-0.40.10.8-0.8-1.41.11.20.11.01.21.31.21.20.91.3-0.20.1
Compulsive drug intake1.01.02.31.21.5-1.5-1.3-1.50.81.4-1.4-0.21.21.40.90.80.10.90.30.1-0.50.40.10.3
One hour access (shock baseline)0.20.20.8-0.3-0.00.10.80.8-0.9-0.40.4-0.6-0.3-0.3-0.8-0.30.4-0.00.20.40.60.30.40.4
Social response proportion3.53.88.0-2.4-2.82.82.62.6-1.8-2.72.70.7-2.5-2.4-2.0-1.6-0.6-2.2-0.9-0.40.6-0.90.50.3
Social responses1.01.33.3-1.1-1.81.81.11.3-0.3-1.71.7-0.4-1.7-1.6-1.2-0.50.0-1.4-0.30.10.6-0.4-0.6-0.6
Social time0.30.41.30.70.4-0.5-1.1-1.01.20.7-0.7-0.20.30.3-0.00.3-0.3-0.0-0.2-0.4-0.7-0.5-0.6-0.6
Soleus weight3.510.316.8-3.6-2.62.62.82.1-3.7-2.22.23.9-3.0-2.9-3.5-3.8-3.5-3.4-3.5-3.3-2.4-3.13.84.1
Bone: stiffness0.40.71.40.90.9-0.8-0.9-0.60.91.2-1.2-0.80.70.60.70.60.80.70.80.70.40.4-0.7-1.2
Tibialis anterior weight2.17.217.0-2.5-1.31.31.30.7-2.7-0.40.43.9-1.8-1.6-2.6-3.3-3.7-2.4-3.5-3.5-3.1-2.93.94.1
Time to tail flick, vehicle, before self-admin3.53.55.92.22.1-2.0-1.0-1.01.10.9-0.9-1.42.12.21.92.42.32.32.42.31.72.4-1.5-1.8
Time to tail flick, vehicle, after self-admin1.01.13.6-0.9-0.80.91.81.5-1.9-1.81.80.4-0.9-0.8-1.1-0.40.3-0.40.10.40.80.30.90.7
Time to tail flick, test, before self-admin0.70.62.30.71.0-1.0-1.1-0.91.01.5-1.5-0.60.70.80.70.40.10.70.30.0-0.20.2-0.5-0.2
Time to tail flick, test, after self-admin1.21.25.00.6-0.10.1-0.10.31.1-0.40.4-1.10.30.40.91.31.60.81.61.61.71.3-2.2-1.3
Delta time to tail flick, vehicle, before/after SA1.51.53.2-1.3-1.31.31.71.5-1.8-1.71.70.3-1.3-1.3-1.4-1.0-0.3-1.0-0.5-0.20.3-0.51.01.1
Delta time to tail flick, test, before/after SA1.21.02.7-0.7-1.41.41.21.4-0.3-1.61.6-0.1-0.9-0.9-0.40.10.9-0.40.71.01.50.6-1.3-0.8
Tibia length7.120.132.75.75.2-5.2-5.2-4.95.44.6-4.6-3.65.55.15.55.03.15.03.62.80.93.1-3.4-3.2
Ambulatory time before self-admin0.50.52.10.10.7-0.7-0.4-0.6-0.40.9-0.90.50.10.3-0.2-0.6-0.7-0.1-0.7-0.9-1.1-0.61.40.8
Ambulatory time after self-admin2.32.54.0-1.8-1.41.41.31.0-1.7-0.80.81.9-1.3-1.4-1.8-2.0-1.8-1.5-1.9-1.8-1.3-1.62.01.9
Bone: tissue strength0.30.31.00.60.6-0.6-1.0-0.91.00.7-0.7-0.20.30.30.90.20.00.10.1-0.1-0.5-0.2-0.4-0.5
Total heroin consumption0.30.42.40.00.6-0.60.2-0.2-0.90.3-0.30.90.10.1-0.3-0.4-0.60.0-0.5-0.5-0.6-0.31.51.1
Bone: trabecular number0.50.81.31.11.0-1.0-0.9-0.71.01.1-1.1-1.01.00.80.40.80.91.00.90.70.50.7-0.9-1.1
Bone: trabecular spacing0.91.22.4-1.3-1.21.10.80.6-0.9-0.90.91.6-1.1-1.1-0.5-1.2-1.4-1.2-1.3-1.3-0.9-1.11.01.2
Bone: trabecular thickness1.62.03.71.71.9-1.8-1.2-1.00.81.8-1.8-0.71.71.80.91.21.41.71.51.20.71.2-0.6-0.9
Bone: trabecular tissue density0.81.12.1-1.3-0.90.90.70.6-1.0-0.30.31.1-1.0-0.9-1.0-1.3-1.4-1.1-1.5-1.2-0.9-1.31.31.3
Water consumed over 24 hours0.30.42.50.50.8-0.8-0.5-0.50.20.9-0.9-1.60.60.70.10.10.30.40.10.2-0.10.10.10.2
Number of responses in last shaping day0.10.20.5-0.3-0.20.20.10.1-0.2-0.00.00.4-0.3-0.5-0.7-0.5-0.4-0.4-0.4-0.5-0.4-0.50.40.4