Hub : Genes

Nudt15

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr15_55121464_55123103 0.41 0.15 0.0e+00 0.17 0.17 0.17 0.17 4.3e-18 3.0e-18 5.6e-18 6.8e-18
2 PL intron excision ratio chr15_55121464_55122799 0.45 0.16 5.6e-17 0.16 0.16 0.17 0.16 5.9e-17 1.7e-17 5.6e-18 1.1e-16
3 NAcc intron excision ratio chr15_55121464_55123103 0.1 0.05 4.0e-13 0.08 0.08 0.09 0.09 1.1e-12 1.6e-12 5.4e-13 1.9e-13
4 IC intron excision ratio chr15_55121464_55122799 0.12 0.06 6.9e-05 0.1 0.09 0.09 0.06 4.8e-05 2.0e-04 9.0e-05 2.4e-03
5 IC intron excision ratio chr15_55121464_55123103 0.12 0.06 5.9e-05 0.1 0.09 0.09 0.06 4.2e-05 1.8e-04 9.4e-05 2.5e-03
6 Brain intron excision ratio chr15_55121464_55123103 0.15 0.07 5.7e-10 0.1 0.11 0.11 0.11 6.8e-10 1.2e-10 1.1e-10 1.9e-10
7 BLA intron excision ratio chr15_55121464_55123103 0.08 0.06 3.5e-03 0.02 0.04 0.02 0.02 4.2e-02 5.4e-03 4.6e-02 3.3e-02
8 BLA intron excision ratio chr15_55121464_55122799 0.08 0.06 3.4e-03 0.02 0.04 0.02 0.02 4.1e-02 5.2e-03 4.5e-02 3.2e-02
9 pVTA gene expression Nudt15 0.38 0.12 0.0e+00 0.28 0.32 0.32 0.28 7.7e-23 4.1e-26 5.0e-26 2.2e-22
10 Adipose intron excision ratio chr15_55121464_55123103 0.02 0.02 8.9e-03 0.02 0.01 0.01 0.01 4.5e-03 2.1e-02 1.1e-02 1.4e-02
11 pVTA intron excision ratio chr15_55121464_55122799 0.26 0.13 5.1e-13 0.18 0.17 0.18 0.18 2.3e-14 1.5e-13 2.3e-14 2.7e-14
12 pVTA intron excision ratio chr15_55121464_55123103 0.24 0.12 1.6e-12 0.17 0.16 0.17 0.17 5.7e-14 3.1e-13 7.6e-14 6.7e-14
13 Adipose gene expression Nudt15 0.07 0.04 3.5e-07 0.04 0.05 0.05 0.05 4.0e-05 2.0e-06 2.0e-06 1.7e-06
14 Liver intron excision ratio chr15_55121464_55123103 0.08 0.04 2.7e-08 0.07 0.06 0.06 0.06 5.7e-08 1.9e-07 2.8e-07 1.4e-07
15 LHb gene expression Nudt15 0.49 0.15 1.1e-09 0.3 0.36 0.37 0.38 9.8e-08 2.1e-09 8.1e-10 5.3e-10
16 Brain mRNA stability Nudt15 0.09 0.04 8.1e-09 0.07 0.09 0.09 0.08 5.9e-07 8.1e-09 2.6e-08 7.4e-08
17 Brain gene expression Nudt15 0.51 0.13 0.0e+00 0.37 0.38 0.38 0.39 8.5e-36 1.5e-37 4.9e-37 1.8e-38
18 IC gene expression Nudt15 0.4 0.13 1.5e-15 0.35 0.34 0.33 0.33 1.8e-15 1.0e-14 2.2e-14 1.8e-14
19 PL gene expression Nudt15 0.37 0.09 0.0e+00 0.37 0.38 0.38 0.38 5.6e-42 3.7e-44 2.1e-43 7.2e-44
20 BLA gene expression Nudt15 0.47 0.14 0.0e+00 0.31 0.3 0.3 0.32 8.3e-17 1.5e-16 3.4e-16 1.6e-17
21 NAcc gene expression Nudt15 0.35 0.09 0.0e+00 0.31 0.44 0.44 0.44 2.7e-48 1.3e-73 1.3e-73 7.1e-74
22 OFC gene expression Nudt15 0.25 0.12 1.1e-04 0.21 0.15 0.18 0.19 8.7e-06 2.6e-04 5.5e-05 2.4e-05
23 IL gene expression Nudt15 0.36 0.14 6.9e-07 0.24 0.23 0.22 0.24 1.3e-06 2.5e-06 6.6e-06 2.2e-06
24 Liver gene expression Nudt15 0.06 0.04 3.7e-06 0.05 0.05 0.04 0.04 2.4e-06 4.5e-06 2.8e-05 9.9e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.20.41.9-0.9-1.1-0.6-0.60.60.5-1.41.40.50.4-0.60.60.30.30.4-0.20.3-0.20.30.1-0.1-0.20.2-0.3
Area under the delay curve0.40.62.2-1.2-1.5-1.1-0.60.60.9-1.51.50.50.7-0.60.60.70.70.2-0.10.10.1-0.3-0.2-0.90.20.20.1
BMI with tail0.00.10.60.80.70.70.2-0.2-0.60.2-0.2-0.3-0.0-0.00.0-0.2-0.2-0.1-0.3-0.00.10.30.20.7-0.6-0.2-0.1
BMI without tail0.10.52.01.11.01.10.4-0.4-0.80.9-0.9-0.3-0.60.5-0.5-0.5-0.50.1-0.20.3-0.40.80.81.4-0.7-0.9-0.6
Body weight0.31.43.6-1.1-1.1-1.2-1.21.21.4-0.90.91.50.8-1.91.91.81.81.01.30.7-0.60.80.80.4-0.7-1.3-0.5
Weight adjusted by age0.61.74.71.10.80.20.7-0.7-0.70.6-0.6-1.7-0.21.3-1.3-1.3-1.3-1.2-1.4-1.81.5-2.2-2.0-1.81.02.10.9
Bone surface0.30.63.2-1.3-1.7-1.0-0.40.40.7-1.81.80.50.7-0.70.70.30.30.0-0.30.10.20.0-0.2-0.70.00.50.5
Bone volume0.30.73.6-1.4-1.7-1.0-0.60.60.8-1.91.90.60.4-0.70.70.50.50.3-0.40.1-0.00.2-0.1-0.50.20.30.2
Breakpoint value in progressive ratio session0.20.32.0-0.3-0.50.10.5-0.5-0.10.2-0.2-0.1-1.40.1-0.1-0.0-0.0-0.4-0.4-0.20.1-0.1-0.1-0.01.4-0.01.3
Number of licking bursts0.31.12.8-0.7-0.5-0.2-0.40.40.8-0.0-0.01.20.1-0.90.91.31.31.01.21.4-1.31.51.61.3-0.9-1.7-0.9
Context. condit. distance diff. score1.92.210.11.31.71.90.8-0.8-1.11.5-1.50.4-1.00.1-0.10.10.10.80.61.4-1.72.32.03.2-1.6-2.5-1.7
Locomotion velocity, session 11.01.22.80.40.3-0.00.5-0.5-0.6-0.00.0-1.2-0.60.9-0.9-1.2-1.2-0.9-1.4-1.61.2-1.7-1.6-1.51.51.61.3
Locomotion distance, session 10.50.72.3-1.3-1.5-1.3-0.80.81.0-1.41.40.40.6-0.50.50.50.50.2-0.1-0.20.3-0.6-0.5-1.30.50.50.5
Locomotion velocity, session 20.30.41.6-0.8-0.9-1.0-0.60.60.5-0.70.7-0.10.50.3-0.30.10.10.3-0.2-0.20.1-0.7-0.6-1.30.41.00.4
Locomotion distance, session 21.52.17.0-2.3-2.6-2.3-1.51.51.8-2.42.40.70.9-0.80.81.01.00.4-0.3-0.20.5-1.0-0.9-2.20.91.00.7
Locomotion velocity, session 30.30.30.70.70.70.70.4-0.4-0.80.8-0.8-0.4-0.50.6-0.6-0.6-0.60.2-0.20.1-0.60.40.20.8-0.2-0.1-0.3
Locomotion distance, session 30.40.52.30.30.20.60.2-0.2-0.40.6-0.60.3-0.3-0.00.00.10.10.70.40.8-1.21.31.11.5-0.8-1.2-0.7
Stereotopy head waving bouts, day 30.80.92.01.01.10.50.6-0.6-0.71.0-1.0-1.3-0.81.3-1.3-1.0-1.0-0.8-0.8-1.10.8-1.3-0.9-0.90.71.40.5
Stereotopy head waving duration, day 30.60.82.20.40.60.20.4-0.4-0.30.2-0.2-1.1-0.80.8-0.8-0.6-0.6-0.9-1.1-1.21.1-1.5-1.3-1.31.11.40.7
Locomotion velocity, session 73.94.316.40.91.11.4-0.40.4-1.11.7-1.70.9-0.30.0-0.0-0.3-0.32.31.52.8-3.23.43.14.1-3.1-2.5-3.3
Locomotion distance, session 72.22.812.31.11.11.50.1-0.1-1.41.5-1.50.5-0.60.1-0.1-0.8-0.81.50.92.1-2.42.82.33.5-2.3-1.9-2.4
Stereotopy head waving bouts, day 70.30.31.3-0.8-0.5-1.0-0.80.81.0-0.60.60.10.5-0.00.00.50.50.40.1-0.2-0.0-0.7-0.3-1.10.00.4-0.1
Stereotopy head waving duration, day 70.20.31.6-0.20.1-0.5-0.20.20.5-0.00.0-0.30.10.4-0.40.20.2-0.3-0.2-0.60.5-1.1-0.6-1.30.60.60.3
Locomotion velocity, session 80.30.41.1-0.30.10.1-0.30.30.4-0.00.00.6-0.2-0.10.10.70.70.80.40.8-1.00.91.10.9-0.7-1.0-0.8
Locomotion distance, session 81.11.52.7-1.3-1.1-0.7-1.11.11.0-1.11.11.40.6-1.11.11.41.41.60.81.4-1.61.61.41.0-1.1-1.6-1.3
Degree of sensitization distance0.90.93.50.90.81.00.1-0.1-1.11.1-1.1-0.1-0.50.5-0.5-1.1-1.10.70.31.2-1.11.41.11.9-1.3-0.6-1.3
Degree of sensitization stereotypy0.30.31.0-0.9-0.7-0.9-0.60.61.0-0.50.50.50.5-0.40.40.80.80.50.50.2-0.3-0.10.1-0.60.1-0.2-0.0
Conditioned locomotion0.60.71.81.31.31.31.2-1.2-1.11.2-1.2-0.6-0.70.6-0.6-0.5-0.5-0.6-0.2-0.30.20.20.00.9-0.3-0.10.4
Cocaine response after cond. corrected2.03.05.62.42.32.12.2-2.2-2.32.2-2.1-1.8-2.01.8-1.8-2.2-2.2-1.5-1.3-1.00.8-0.6-0.80.60.81.00.9
Cocaine response after cond. not corrected0.71.02.11.41.21.11.2-1.2-1.41.2-1.2-1.1-1.11.2-1.2-1.5-1.5-0.6-0.8-0.50.1-0.2-0.40.50.30.50.2
Cocaine response before conditioning3.54.27.6-2.7-2.8-2.6-2.52.52.5-2.42.42.22.3-2.02.02.22.22.21.61.6-1.71.11.2-0.3-1.3-1.3-1.4
Saline control response1.52.04.3-1.9-2.0-1.7-1.41.41.8-1.21.21.80.8-2.02.02.12.11.01.51.0-0.80.80.80.0-0.3-1.3-0.2
Bone: connectivity density0.30.51.3-0.7-0.7-0.5-0.60.60.5-0.60.60.90.9-1.11.10.60.60.50.90.8-0.40.80.50.5-0.8-0.5-0.3
Bone: cortical apparent density0.91.45.21.81.91.81.4-1.4-1.42.3-2.3-0.7-1.10.9-0.9-0.5-0.5-0.70.2-0.10.10.30.41.3-0.1-0.30.1
Bone: cortical area0.10.20.9-0.6-0.7-0.3-0.20.20.2-0.91.00.10.4-0.10.1-0.2-0.20.0-0.30.10.2-0.0-0.1-0.5-0.30.5-0.1
Bone: cortical porosity2.32.54.9-1.9-1.6-2.2-2.12.12.2-2.22.21.51.7-1.81.82.12.11.30.90.4-0.50.20.2-0.7-0.7-0.7-1.0
Bone: cortical porosity2.02.25.1-1.9-1.7-2.0-1.81.82.1-2.32.31.31.5-1.71.72.02.01.00.70.2-0.30.00.1-0.9-0.4-0.6-0.6
Bone: cortical thickness0.20.30.8-0.7-0.5-0.4-0.60.60.4-0.40.40.70.6-0.50.50.40.40.70.70.8-0.60.80.70.3-0.9-0.2-0.8
Bone: cortical thickness0.30.41.00.40.30.90.7-0.7-0.81.0-1.0-0.1-0.70.6-0.6-0.6-0.60.00.10.7-0.50.80.71.0-0.3-0.0-0.3
Bone: cortical tissue density0.91.45.51.81.91.81.5-1.5-1.42.3-2.3-0.6-1.20.9-0.9-0.4-0.4-0.70.2-0.00.00.40.51.4-0.1-0.40.0
Condit. Reinf. active minus inactive responses0.60.71.9-1.0-0.7-1.4-1.41.41.1-0.60.60.71.2-0.80.80.90.90.80.90.1-0.2-0.3-0.2-1.0-0.40.3-0.3
Condit. Reinf. active-inactive response ratio0.80.91.51.21.20.60.7-0.7-0.91.0-1.1-1.2-0.51.1-1.1-0.9-0.9-0.9-0.7-1.21.0-1.2-1.1-0.60.61.10.7
Condit. Reinf. active responses2.12.64.9-2.2-2.0-2.2-2.22.22.0-1.41.41.82.1-1.71.71.71.71.81.81.2-1.20.50.6-0.7-1.1-0.5-1.0
Condit. Reinf. inactive responses5.06.511.8-3.4-3.2-2.9-2.72.73.1-2.72.73.12.7-3.03.03.03.02.52.52.2-2.01.51.5-0.2-1.5-1.7-1.5
Incentive salience index mean3.03.87.6-2.3-2.1-2.7-2.72.72.4-1.81.72.02.8-2.22.22.22.22.12.11.1-1.20.40.5-0.9-1.5-0.5-1.2
Condit. Reinf. lever presses5.27.813.0-3.2-3.2-3.4-3.33.33.4-2.42.43.23.6-3.33.33.23.23.03.12.2-2.21.41.5-0.4-2.3-1.5-1.9
Condit. Reinf. active minus inactive responses0.20.21.4-0.0-0.1-0.2-0.50.5-0.10.5-0.50.20.6-0.10.1-0.2-0.20.50.70.7-0.30.40.50.3-1.1-0.0-1.2
Condit. Reinf. active-inactive response ratio0.10.20.90.40.10.1-0.20.2-0.50.3-0.3-0.30.20.4-0.4-0.7-0.70.3-0.10.2-0.20.10.10.2-0.70.3-1.0
Condit. Reinf. active responses0.30.51.9-0.4-0.5-0.4-0.80.80.20.0-0.00.70.8-0.40.40.10.10.81.01.1-0.60.80.90.6-1.3-0.4-1.4
Condit. Reinf. inactive responses0.91.32.5-1.3-1.2-0.8-1.01.00.9-0.60.61.51.0-1.41.41.11.11.11.51.6-1.11.41.30.8-1.0-1.1-0.9
Condit. Reinf. lever presses1.21.84.4-1.7-1.5-1.7-1.71.71.6-1.81.81.22.1-1.41.41.51.51.00.90.6-0.30.20.2-0.8-1.0-0.2-1.1
Condit. Reinf. lever reinforcers received0.60.92.3-0.8-0.9-0.8-1.11.10.6-0.40.41.01.1-0.80.80.50.51.11.11.2-0.81.01.00.5-1.4-0.6-1.5
Conditioned reinforcement - actives0.20.71.61.21.11.21.1-1.1-1.31.3-1.3-0.8-0.71.0-1.0-1.1-1.1-0.6-0.4-0.10.20.20.10.8-0.00.10.1
Conditioned reinforcement - inactives1.23.24.7-1.8-1.9-2.1-2.12.12.0-1.81.82.02.2-2.02.02.02.02.01.71.5-1.61.21.20.2-1.7-1.3-1.5
Conditioned locomotion0.30.41.30.10.20.50.7-0.7-0.4-0.70.7-0.6-0.20.3-0.3-0.3-0.3-1.0-1.1-0.71.2-0.6-0.8-0.60.70.70.6
Patch foraging indifference point 0 sec2.67.311.0-3.3-3.2-2.9-3.13.13.1-2.42.43.23.1-2.82.83.03.02.92.92.6-2.41.92.10.0-2.1-2.1-1.9
Patch foraging indifference point AUC1.02.35.21.61.11.51.5-1.5-2.01.1-1.1-1.9-1.42.2-2.2-2.3-2.3-1.3-1.9-1.10.9-0.7-0.90.00.81.30.7
Delay disc. indifference point, 0s delay0.50.62.8-0.4-0.2-0.9-0.50.50.7-0.90.9-0.20.9-0.20.20.30.3-0.2-0.3-0.90.9-1.3-1.1-1.7-0.01.1-0.0
Delay disc. indifference point, 16s delay0.30.41.7-1.1-1.3-0.7-0.30.30.8-1.11.10.50.2-0.60.60.70.7-0.0-0.10.10.2-0.1-0.1-0.60.5-0.00.3
Delay disc. indifference point, 2s delay1.51.74.50.70.80.20.7-0.7-0.5-0.40.4-1.6-0.11.1-1.1-1.0-1.0-1.5-1.8-1.92.0-2.1-2.1-1.90.91.90.7
Delay disc. indifference point, 24s delay0.00.10.2-0.0-0.20.10.4-0.4-0.2-0.20.2-0.2-0.30.2-0.2-0.2-0.2-0.3-0.5-0.00.2-0.0-0.2-0.00.20.10.0
Delay disc. indifference point, 4s delay0.60.61.50.30.10.20.5-0.5-0.5-0.10.1-0.9-0.20.8-0.8-0.8-0.8-0.9-1.1-1.01.1-1.1-1.0-1.10.81.20.8
Delay disc. indifference point, 8s delay0.61.12.8-1.3-1.7-1.2-1.01.01.1-1.21.21.20.8-1.21.21.21.20.90.81.0-0.90.80.90.1-0.4-0.9-0.3
Indifference point function ln k0.92.76.0-1.6-1.1-1.5-1.61.62.0-1.21.22.11.8-2.52.52.42.41.52.11.2-1.11.01.10.3-1.0-1.6-0.9
Indifference point function log k0.92.76.0-1.6-1.1-1.5-1.61.62.0-1.21.22.11.8-2.52.52.42.41.52.11.2-1.11.01.10.3-1.0-1.6-0.9
Patch foraging total patch changes 0 sec2.57.311.8-3.4-3.3-3.0-3.13.13.2-2.42.43.22.9-2.82.83.13.12.92.92.5-2.41.92.1-0.0-1.9-2.1-1.8
Patch foraging total patch changes 12 sec1.31.75.6-2.1-2.4-1.7-1.51.51.5-1.71.71.41.4-1.11.11.01.01.30.91.1-1.10.70.8-0.5-0.6-0.4-0.7
Patch foraging total patch changes 18 sec0.30.82.0-1.0-1.0-0.4-0.70.70.6-0.30.31.10.3-0.50.50.80.81.11.01.3-1.41.31.30.9-0.7-1.2-0.8
Patch foraging total patch changes 24 sec0.72.55.4-2.3-2.3-1.8-2.02.01.9-1.81.81.81.4-1.51.51.61.61.61.31.4-1.11.01.1-0.2-1.0-1.0-1.2
Patch foraging total patch changes 6 sec1.62.65.4-1.4-1.3-0.7-1.41.41.2-0.30.32.01.1-1.31.31.51.51.92.02.3-2.12.22.31.6-1.6-2.1-1.8
Patch foraging time to switch 0 sec0.00.00.10.00.2-0.3-0.10.10.2-0.10.1-0.00.1-0.10.10.20.20.00.1-0.30.2-0.3-0.2-0.2-0.10.20.2
Patch foraging water rate 0 sec0.41.62.9-1.6-1.4-0.9-1.11.11.5-1.01.01.70.7-1.61.61.71.71.11.31.3-1.01.31.30.5-0.5-1.4-1.1
Patch foraging water rate 12 sec0.00.10.50.40.60.30.1-0.10.00.7-0.70.1-0.0-0.10.10.30.3-0.20.5-0.00.3-0.10.20.2-0.2-0.3-0.2
Patch foraging water rate 18 sec0.10.31.10.70.81.10.8-0.8-0.50.8-0.80.0-0.6-0.00.00.10.1-0.20.20.3-0.00.50.61.0-0.0-0.7-0.3
Patch foraging water rate 24 sec0.60.82.9-0.10.30.80.3-0.3-0.11.0-1.00.9-0.6-0.50.50.40.40.51.21.4-1.11.51.51.7-0.5-1.4-0.8
Patch foraging water rate 6 sec0.10.20.9-0.5-0.1-0.1-0.10.10.4-0.40.40.2-0.5-0.60.60.50.5-0.5-0.1-0.40.7-0.4-0.4-0.51.00.00.3
Seeking ratio, delayed vs. immediate footshock0.20.31.60.81.20.1-0.10.1-0.30.9-0.9-0.50.60.3-0.3-0.4-0.4-0.10.3-0.50.3-0.7-0.5-0.4-0.60.6-0.5
Distance traveled before self-admin0.81.74.60.50.6-0.10.7-0.7-0.4-0.30.3-1.4-0.60.8-0.8-0.8-0.8-1.6-1.6-2.02.0-2.1-2.1-1.91.71.91.3
Distance traveled after self-admin1.73.14.61.81.91.72.1-2.1-1.91.1-1.1-2.0-2.01.7-1.7-1.8-1.8-2.2-2.1-1.81.9-1.6-1.6-0.61.81.61.6
Extensor digitorum longus weight4.116.530.32.72.52.44.0-4.0-2.61.1-1.1-4.5-4.13.3-3.3-3.0-3.0-5.4-5.1-5.55.5-5.2-5.1-3.65.44.25.5
Bone: elastic displacement0.30.41.4-1.1-0.9-1.2-0.90.90.9-0.70.70.40.3-0.60.60.40.40.30.3-0.20.1-0.5-0.4-1.00.70.60.2
Bone: elastic work1.41.85.3-2.0-1.9-2.0-1.61.61.8-2.32.30.80.9-1.11.11.01.00.5-0.1-0.20.3-0.7-0.6-1.80.70.70.4
Bone: endosteal estimation0.20.41.4-0.3-0.6-0.4-0.00.00.1-1.21.2-0.40.40.2-0.2-0.5-0.5-0.4-0.9-0.70.6-0.7-0.9-1.00.30.80.5
Bone: endosteal perimeter0.30.71.90.0-0.3-0.20.4-0.4-0.3-0.90.9-0.80.40.7-0.7-0.9-0.9-0.8-1.2-1.11.0-1.2-1.2-1.40.51.30.8
Epididymis fat weight0.31.52.8-0.8-0.6-1.3-1.71.71.3-0.70.71.21.5-1.31.31.31.21.51.41.0-1.00.90.90.5-1.6-1.0-1.7
Delta time in closed arm before/after self-admin0.50.41.8-0.40.1-0.2-0.80.80.5-1.11.10.41.2-0.40.40.50.50.60.10.3-0.20.30.3-0.1-1.3-0.4-1.1
Delta time in open arm before/after self-admin0.10.10.2-0.0-0.4-0.30.0-0.0-0.2-0.10.1-0.3-0.10.3-0.3-0.4-0.40.1-0.4-0.2-0.2-0.2-0.2-0.20.50.50.3
Diff in mean of infusions in LGA sessions0.10.21.0-0.6-1.0-0.50.1-0.10.40.2-0.20.4-0.9-0.40.40.30.30.20.20.3-0.50.20.20.11.0-0.20.5
Delay discount exponential model param0.40.52.11.01.30.90.5-0.5-0.71.4-1.4-0.3-0.60.4-0.4-0.5-0.50.00.40.1-0.30.40.41.0-0.3-0.3-0.2
Extinction: sum of active levers before priming0.50.81.5-1.1-1.2-1.0-1.01.01.1-1.01.01.00.4-1.01.00.90.91.10.60.8-1.10.70.70.2-0.4-0.8-0.7
Active lever presses in extinction session 60.70.71.8-0.7-0.7-0.2-0.50.50.5-0.20.21.00.0-0.70.70.70.70.90.81.3-1.11.31.41.1-0.7-1.3-0.7
Bone: final force1.22.03.5-1.6-1.4-1.5-1.91.91.4-1.51.51.51.6-1.41.41.51.51.61.31.3-1.11.21.00.3-1.6-0.7-1.6
Bone: final moment1.22.03.9-1.7-1.5-1.7-2.02.01.5-1.61.61.41.6-1.51.51.41.41.41.21.0-0.80.80.7-0.1-1.4-0.5-1.3
Food consumed during 24 hour testing period0.20.31.4-0.7-0.8-0.7-0.60.60.3-1.21.20.20.9-0.50.50.20.20.4-0.2-0.00.0-0.1-0.2-0.6-0.30.40.1
Glucose0.40.71.90.60.41.41.2-1.2-1.00.5-0.5-0.6-1.31.2-1.2-0.9-0.9-0.4-0.80.3-0.10.60.50.90.1-0.3-0.1
Heart weight0.00.10.40.1-0.0-0.3-0.20.20.1-0.40.4-0.20.50.3-0.3-0.1-0.10.3-0.2-0.1-0.2-0.1-0.0-0.1-0.50.1-0.6
Delay discount hyperbolic model param0.30.41.60.81.00.80.3-0.3-0.51.3-1.3-0.0-0.50.2-0.2-0.2-0.20.20.60.3-0.50.60.61.1-0.4-0.6-0.3
Intermittent access intake day 1-15 change0.63.46.2-1.4-1.3-1.2-1.61.61.5-0.40.42.31.0-1.91.91.91.92.22.42.2-2.42.32.31.8-1.7-2.5-1.8
Intermittent access intake escalation0.73.86.3-1.5-1.4-1.5-1.91.91.7-0.60.62.41.4-2.12.12.12.12.32.52.2-2.42.32.21.7-1.9-2.5-2.0
Intermittent access intake escalation 20.40.82.10.10.40.1-0.50.50.10.4-0.40.80.6-0.50.50.50.51.01.11.0-1.11.31.21.4-1.4-1.3-1.4
Intermitt. access day 1 inactive lever presses0.10.82.4-0.1-0.0-0.0-0.50.50.11.0-1.00.90.2-0.50.50.40.41.11.51.3-1.31.31.41.3-1.2-1.1-1.2
Intermitt. access day 15 inactive lever presses0.31.72.6-1.2-1.2-1.1-1.31.31.3-0.70.71.61.1-1.41.41.41.41.61.61.4-1.61.21.40.6-1.4-1.4-1.5
Intermitt. access escalation Index0.00.00.1-0.10.1-0.10.0-0.00.2-0.20.2-0.0-0.2-0.10.10.10.1-0.1-0.1-0.10.2-0.2-0.3-0.20.30.0-0.1
Intermittent access day 1 total infusions0.51.53.3-1.8-1.8-1.2-1.01.01.3-1.31.31.60.6-1.51.51.41.41.11.01.3-1.21.21.10.4-0.4-1.2-0.1
Intermittent access day 15 total infusions1.74.06.4-2.0-1.9-1.8-2.02.01.9-1.21.22.51.6-2.22.22.22.22.32.42.3-2.32.22.11.2-1.8-2.3-1.7
Intermittent access terminal intake (last 3 days)1.11.93.6-1.1-1.0-0.7-1.11.11.0-0.50.51.70.8-1.41.41.31.31.61.61.8-1.81.91.71.4-1.4-1.9-1.2
Intermittent access total infusions2.63.15.2-1.8-1.8-1.3-1.51.51.6-1.01.02.31.0-1.91.91.91.92.02.02.2-2.12.22.01.4-1.4-2.2-1.1
Intermittent access day 1 locomotion1.52.74.5-2.0-1.8-1.5-1.61.61.7-1.41.42.11.5-2.02.02.02.01.61.81.8-1.51.51.50.6-1.2-1.6-1.2
Intermittent access day 15 total locomotion0.20.62.0-0.6-0.7-0.3-0.40.40.40.1-0.10.90.1-0.60.60.60.61.01.01.3-1.41.31.21.1-0.6-1.1-0.5
Intermittent access total locomotion1.21.42.4-1.3-1.2-1.0-1.11.11.1-0.80.71.50.9-1.31.31.41.41.31.41.4-1.41.31.20.7-0.9-1.3-1.0
Intermittent access standard deviation0.10.63.1-1.4-1.8-0.8-0.30.30.7-0.60.61.0-0.7-0.80.80.70.70.40.50.8-0.70.80.70.40.7-0.70.8
Left kidney weight0.65.110.1-2.4-2.1-2.8-2.82.82.6-2.72.72.33.2-2.72.72.52.52.31.91.4-1.41.00.9-0.4-2.0-1.3-1.7
Right kidney weight0.96.112.3-2.9-2.8-3.3-2.82.83.3-3.53.52.43.4-3.33.33.13.11.61.70.7-0.40.20.3-1.3-1.3-0.9-0.7
Cocaine induced anxiety0.41.24.3-1.1-0.9-1.5-0.90.91.2-1.51.50.21.3-0.80.80.90.9-0.3-0.0-1.01.2-1.4-1.3-2.10.50.90.6
Post-drug Anxiety0.60.72.5-0.8-0.5-1.4-1.21.21.1-0.80.80.61.6-0.90.90.90.90.50.8-0.10.1-0.6-0.4-1.1-0.50.3-0.4
Baseline Anxiety0.50.93.20.30.20.2-0.30.3-0.20.6-0.60.60.2-0.10.10.00.01.30.91.4-1.81.51.41.7-1.4-1.1-1.4
Tail length0.31.72.6-1.3-1.2-1.4-1.61.61.6-1.01.01.61.1-1.41.41.51.51.41.41.0-1.10.91.10.3-0.9-1.5-1.1
Length with tail0.52.44.9-2.1-2.0-2.2-1.71.72.2-1.31.31.91.2-2.12.12.12.11.21.80.7-0.70.40.6-0.5-0.2-1.1-0.2
Length without tail0.10.61.9-0.9-1.0-0.90.0-0.00.7-0.40.40.3-0.1-0.80.80.70.7-0.50.3-0.50.7-0.9-0.8-1.21.10.61.4
Times rat made contact with spout2.52.96.5-1.5-1.2-0.5-1.31.31.0-0.70.72.00.8-1.51.51.81.82.01.82.4-2.22.52.51.9-1.6-2.3-1.6
Lifetime Intake1.92.44.1-1.7-1.7-1.2-1.21.21.4-1.01.02.00.8-1.71.71.71.71.61.71.9-1.81.91.81.2-1.1-2.0-0.9
Liver weight, left0.81.45.9-1.3-1.4-1.9-1.11.11.2-1.31.30.11.0-0.70.70.40.4-0.1-0.0-0.91.0-1.6-1.5-2.40.71.51.0
Liver weight, right0.20.32.0-0.4-0.6-0.00.4-0.40.1-0.50.5-0.1-1.1-0.20.20.20.2-0.6-0.7-0.50.6-0.3-0.3-0.31.3-0.01.4
Locomotor activity2.64.114.9-1.7-1.6-2.1-0.60.61.7-2.72.7-0.11.0-1.01.01.01.0-1.5-1.1-2.42.8-2.9-2.7-3.92.42.32.8
Locomotor testing distance1.43.49.9-2.3-2.0-2.6-1.51.52.4-2.72.70.81.7-1.61.61.81.8-0.30.1-1.31.6-1.9-1.6-3.11.31.31.7
Locomotor testing rearing1.24.411.1-2.8-2.5-3.3-2.22.22.9-3.13.11.32.2-2.02.02.22.20.30.5-1.01.2-1.6-1.4-3.20.80.80.8
Locomotion in novel chamber1.11.53.9-1.8-1.7-1.3-1.11.11.5-2.02.01.40.9-1.51.51.61.60.80.60.7-0.60.70.4-0.1-0.3-0.9-0.2
Locomotion in novel chamber post-restriction0.10.31.10.1-0.20.20.3-0.3-0.4-0.20.2-0.6-0.80.7-0.7-0.7-0.7-0.4-1.0-0.40.3-0.3-0.3-0.20.60.60.5
Fecal boli incidents, locomotor time 10.51.44.3-2.0-2.1-1.2-0.70.71.5-2.02.01.20.1-1.41.41.41.40.10.20.30.20.10.1-0.70.8-0.41.0
Change in fecal boli incidents, locomotor task1.61.73.81.91.91.11.1-1.1-1.51.6-1.6-1.7-0.51.5-1.5-1.5-1.5-1.1-0.9-1.31.0-1.3-1.3-0.50.71.30.5
Time >=10cm from walls, locomotor time 10.70.92.0-1.0-0.8-1.0-1.11.11.2-1.11.11.21.4-1.31.31.31.30.61.10.7-0.20.40.4-0.2-0.7-0.8-0.3
Bouts of movement, locomotor time 10.60.81.51.01.11.21.2-1.2-0.81.2-1.2-0.7-1.20.6-0.6-0.6-0.6-1.2-0.5-0.71.0-0.5-0.60.20.90.30.7
Total resting periods, locomotor time 11.11.22.21.31.41.51.5-1.5-1.21.4-1.4-1.0-1.41.0-1.0-0.9-0.9-1.4-0.7-0.91.2-0.6-0.80.21.00.50.9
Rest time, locomotor task time 10.71.12.90.70.50.91.2-1.2-0.90.3-0.3-1.1-1.30.9-0.9-0.9-0.9-1.4-1.4-1.11.3-0.9-1.2-0.61.51.01.7
Distance moved, locomotor task time 10.41.12.8-0.2-0.4-0.6-1.01.00.50.5-0.50.91.1-0.40.40.50.51.51.51.4-1.71.21.41.0-1.5-1.0-1.7
Vertical activity count, locomotor time 10.00.10.5-0.2-0.1-0.4-0.10.10.2-0.10.1-0.10.2-0.10.10.20.2-0.3-0.0-0.60.5-0.6-0.6-0.70.50.40.3
Time >=10cm from walls, locomotor time 20.51.33.70.81.10.51.0-1.0-0.80.2-0.2-1.2-0.70.8-0.8-0.8-0.8-1.6-1.2-1.61.9-1.6-1.7-1.21.21.31.5
Bouts of movement, locomotor time 20.31.13.10.70.31.11.4-1.4-1.01.0-1.0-1.0-1.81.0-1.0-1.0-1.0-1.3-1.0-0.70.8-0.5-0.6-0.01.60.61.3
Total resting periods, locomotor time 20.20.72.70.3-0.00.91.2-1.2-0.70.7-0.7-0.7-1.60.7-0.7-0.6-0.6-1.1-0.8-0.50.7-0.3-0.40.11.60.41.4
Rest time, locomotor task time 20.20.31.5-0.4-0.80.30.5-0.5-0.1-0.20.20.1-1.2-0.00.0-0.0-0.0-0.2-0.50.2-0.20.30.30.31.1-0.21.2
Distance moved, locomotor task time 20.60.81.9-0.6-0.4-1.1-1.21.20.8-0.30.30.91.4-0.70.70.80.81.11.30.8-0.70.60.50.1-1.3-0.6-1.2
Vertical activity count, locomotor time 20.20.62.00.20.2-0.30.4-0.4-0.1-0.30.3-0.7-0.30.4-0.4-0.3-0.3-0.9-0.9-1.31.2-1.2-1.4-1.10.91.01.0
Light reinforcement 10.52.45.2-0.7-0.4-0.3-1.31.30.8-0.30.31.71.0-1.31.31.31.31.91.72.0-2.12.32.21.9-1.9-2.2-2.2
Light reinforcement 20.71.66.41.41.81.80.8-0.8-1.21.5-1.50.0-0.80.3-0.3-0.5-0.50.40.51.1-1.11.81.52.5-1.4-1.5-1.6
Bone: marrow area0.20.41.6-0.4-0.6-0.5-0.10.10.1-1.31.3-0.30.50.1-0.1-0.5-0.5-0.3-0.9-0.60.6-0.7-0.8-1.00.20.80.4
Bone: maximum diameter0.51.02.70.80.60.91.1-1.1-1.20.2-0.1-1.2-0.61.3-1.3-1.7-1.7-1.1-1.4-0.80.9-0.7-0.7-0.40.41.20.7
Bone: maximum force0.71.43.6-1.7-1.7-1.6-1.61.61.3-1.91.91.01.2-1.11.11.01.01.00.50.6-0.40.40.2-0.6-0.90.1-0.8
Bone: maximum moment0.91.64.4-1.8-1.9-1.9-1.81.81.5-2.12.11.01.4-1.21.21.11.10.90.40.4-0.10.1-0.1-1.0-0.70.4-0.6
Mean time between licks in bursts0.00.10.30.00.3-0.1-0.30.3-0.1-0.10.10.10.30.3-0.3-0.0-0.00.50.10.2-0.50.40.20.2-0.40.0-0.5
Mean num. licks in bursts0.00.10.2-0.4-0.4-0.0-0.30.3-0.0-0.50.50.20.2-0.20.2-0.0-0.00.10.00.30.10.30.20.1-0.10.00.1
Cd content in liver0.70.72.7-0.8-0.4-0.50.0-0.00.5-0.80.7-0.1-0.6-0.30.30.70.7-0.8-0.5-1.01.2-1.1-1.1-1.41.60.81.4
Co content in liver3.84.47.92.02.02.32.6-2.6-2.21.7-1.7-2.3-2.82.4-2.4-1.9-1.9-2.5-2.4-1.91.8-1.5-1.4-0.42.31.32.4
Cu content in liver0.60.71.40.80.91.01.2-1.2-1.21.0-1.0-0.7-0.71.0-1.0-0.9-0.9-0.8-0.5-0.30.5-0.3-0.4-0.00.80.60.8
Fe content in liver0.10.20.60.40.2-0.2-0.20.20.00.5-0.50.10.7-0.00.0-0.0-0.00.50.60.5-0.60.20.30.4-0.8-0.2-0.5
K content in liver1.01.02.7-0.0-0.10.1-0.20.20.30.1-0.11.01.0-0.60.60.80.81.11.21.5-1.51.51.41.4-1.5-1.7-1.4
Mg content in liver0.20.30.90.10.00.50.4-0.4-0.30.2-0.20.20.40.2-0.2-0.0-0.00.50.40.9-0.90.80.80.8-0.7-0.6-0.7
Mn content in liver0.20.20.60.50.50.80.7-0.7-0.50.1-0.1-0.4-0.60.6-0.6-0.4-0.4-0.5-0.6-0.20.20.00.00.20.4-0.30.4
Na content in liver1.41.64.5-1.6-1.3-2.0-1.31.31.8-2.12.10.61.6-1.01.01.21.20.20.1-0.50.5-1.2-1.0-2.10.20.70.2
Rb content in liver0.20.21.10.50.70.60.6-0.6-0.41.0-1.10.1-0.3-0.10.10.10.1-0.20.50.2-0.20.20.20.60.2-0.60.2
Se content in liver1.11.35.9-0.10.3-0.9-0.20.20.4-0.80.8-0.90.50.2-0.2-0.0-0.0-0.9-1.0-1.61.5-2.2-2.2-2.41.12.01.1
Sr content in liver1.21.12.40.50.40.40.7-0.7-0.8-0.20.2-1.2-0.71.0-1.0-1.0-1.0-1.2-1.5-1.31.4-1.3-1.3-1.21.01.61.3
Zn content in liver0.20.21.0-0.6-0.4-0.40.1-0.10.1-0.50.5-0.10.10.1-0.10.10.2-0.2-0.3-0.30.3-0.6-0.6-1.00.70.80.6
Bone: minimum diameter0.30.52.1-1.1-1.3-0.8-0.50.50.4-1.51.50.10.7-0.20.2-0.3-0.3-0.2-0.5-0.20.7-0.5-0.6-1.20.01.00.3
Time in familiar zone, hab. session 10.70.81.9-0.4-0.3-0.1-0.70.70.6-0.40.40.90.6-0.80.80.90.91.10.81.1-1.11.11.31.0-1.2-1.4-1.4
Time in novel zone, hab. session 14.34.86.92.01.81.92.5-2.5-2.32.1-2.1-2.4-2.52.6-2.6-2.5-2.5-2.4-2.0-2.01.9-1.7-1.8-0.72.32.12.2
Total zone transitions, hab. session 10.30.41.6-0.5-0.8-0.7-0.30.30.1-0.60.6-0.4-0.00.2-0.2-0.5-0.5-0.2-0.6-0.50.5-0.8-0.8-1.10.61.30.5
Total locomotion distance, hab. session 10.50.72.4-1.1-1.4-1.4-1.01.00.7-1.11.10.10.9-0.30.30.00.00.1-0.1-0.30.5-0.9-0.9-1.50.31.00.3
Locomotion velocity, hab. session 11.42.05.2-2.1-2.1-2.3-1.81.81.8-2.32.30.91.6-1.31.31.11.10.60.3-0.10.4-0.7-0.8-1.80.10.60.0
Time in familiar zone, hab. session 21.01.12.41.31.51.61.5-1.5-1.10.9-0.9-1.0-1.50.6-0.6-0.8-0.8-1.3-1.0-0.91.0-0.4-0.50.41.10.01.0
Time in novel zone, hab. session 20.20.20.9-0.7-1.0-0.8-0.70.70.3-0.30.30.10.30.4-0.4-0.1-0.10.50.10.2-0.3-0.1-0.1-0.6-0.10.6-0.2
Total zone transitions, hab. session 20.91.24.2-1.0-1.2-1.1-0.20.20.9-1.21.2-0.10.2-0.40.40.50.5-0.9-0.5-1.31.6-1.6-1.4-2.11.60.91.6
Total locomotion distance, hab. session 20.50.72.7-1.1-1.2-1.1-0.30.30.8-0.90.90.10.4-0.40.40.20.2-0.6-0.2-0.81.1-1.1-1.1-1.61.20.81.0
Locomotion velocity, hab. session 20.81.14.2-1.2-1.4-1.3-0.40.40.9-1.31.30.00.4-0.40.40.20.2-0.7-0.4-1.01.3-1.4-1.4-2.11.41.11.3
Novel to familiar place preference ratio1.21.63.9-1.7-2.0-1.5-1.81.81.4-0.70.71.40.9-0.80.80.90.91.71.41.6-1.31.01.30.0-1.0-0.6-1.1
Novelty place preference1.52.04.2-1.8-2.0-1.7-2.12.11.6-0.80.81.51.0-0.90.91.11.11.91.51.7-1.41.11.40.1-1.1-0.8-1.3
Time in novel zone, NPP test1.21.43.4-1.6-1.7-1.5-1.81.81.4-0.70.71.30.8-0.60.60.90.91.61.21.4-1.20.91.2-0.0-0.9-0.5-1.1
Total zone transitions, NPP test0.60.93.5-1.6-1.9-1.3-0.70.71.2-1.31.30.90.8-1.01.01.11.10.20.50.20.2-0.1-0.1-0.90.4-0.20.4
Total locomotion distance, NPP test1.21.75.2-2.1-2.3-1.8-1.41.41.6-1.71.71.51.4-1.51.51.41.40.91.10.8-0.40.50.3-0.6-0.3-0.6-0.3
Locomotion velocity, NPP test1.52.25.8-2.2-2.4-1.9-1.61.61.8-1.61.61.81.6-1.81.81.71.71.11.41.1-0.60.80.6-0.4-0.5-0.9-0.5
Intraocular pressure0.50.92.0-1.0-1.1-0.8-1.21.20.70.0-0.01.00.5-0.50.50.40.41.31.21.4-1.31.21.30.7-0.9-0.6-1.2
Delta distance traveled before/after self-admin1.82.05.01.81.72.21.9-1.9-1.92.0-2.0-1.2-2.01.4-1.4-1.5-1.5-1.1-0.8-0.10.30.30.21.30.50.10.7
Delta ambulatory time before/after self-admin0.61.02.51.11.11.61.4-1.4-1.31.4-1.4-0.7-1.60.9-0.9-0.9-0.9-0.9-0.5-0.10.30.30.21.00.6-0.10.9
Parametrial fat weight0.92.14.2-1.1-0.9-0.7-1.41.41.0-0.20.21.71.1-1.31.31.31.31.72.02.1-1.62.02.01.4-1.8-1.8-1.7
Pavlov. Cond. lever latency3.13.95.92.01.82.02.4-2.4-2.21.4-1.4-2.4-2.12.4-2.4-2.3-2.3-2.2-2.3-1.81.6-1.4-1.5-0.41.81.71.5
Pavlov. Cond. magazine entry latency0.70.91.5-0.5-0.9-0.8-1.01.00.7-0.20.21.00.9-1.11.10.70.71.11.21.2-1.01.01.10.8-1.2-1.1-0.8
Pavlov. Cond. change in total contacts1.92.04.0-1.8-2.0-1.9-1.81.81.7-1.11.11.71.4-1.81.81.51.51.41.61.3-0.90.70.8-0.2-0.9-0.7-0.6
Pavlov. Cond. index score3.24.06.6-1.9-2.0-2.1-2.42.42.2-1.41.42.42.1-2.62.62.32.32.22.31.9-1.71.61.60.6-1.8-1.9-1.5
Pavlov. Cond. latency score3.74.76.9-2.0-2.0-2.2-2.62.62.3-1.41.42.52.3-2.62.62.42.42.52.62.1-1.91.81.80.7-2.1-1.9-1.8
Pavlov. Cond. lever contacts4.25.17.9-2.2-2.0-2.1-2.62.62.4-1.61.52.72.3-2.82.82.72.72.52.72.1-1.91.91.90.8-2.1-2.2-1.8
Pavlov. Cond. magazine entry number0.50.71.40.81.20.91.0-1.0-0.80.6-0.6-0.9-0.71.1-1.1-0.8-0.8-0.9-0.9-0.90.7-0.8-0.7-0.40.70.80.4
Pavlov. Cond. intertrial magazine entries1.21.53.0-1.5-0.9-1.3-1.61.61.6-1.41.31.41.7-1.51.51.71.70.91.30.6-0.30.20.3-0.6-0.8-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.2.93.66.2-1.9-2.1-2.0-2.22.22.1-1.51.52.21.9-2.52.52.22.22.02.11.7-1.51.41.50.5-1.6-1.7-1.2
Pavlov. Cond. response bias1.01.32.5-0.9-1.2-1.1-1.21.21.1-0.70.71.31.1-1.61.61.41.41.21.31.0-0.91.00.90.5-1.0-1.2-0.6
Pavlov. Cond. lever latency1.01.54.11.61.31.61.3-1.3-1.52.0-2.0-0.6-1.61.1-1.1-1.3-1.3-0.0-0.10.4-0.80.90.81.8-0.1-0.60.2
Pavlov. Cond. magazine entry latency1.52.16.6-1.9-1.8-1.8-1.51.52.0-2.62.61.21.6-1.71.72.02.00.60.30.10.0-0.1-0.3-1.0-0.3-0.2-0.0
Pavlov. Cond. change in total contacts0.51.34.10.10.1-0.30.4-0.40.0-0.70.7-1.00.10.2-0.2-0.2-0.2-1.4-1.2-1.82.0-2.0-2.0-2.01.31.51.2
Pavlov. Cond. index score1.11.75.4-1.6-1.5-1.7-1.11.11.6-2.32.30.61.4-1.31.31.61.6-0.1-0.2-0.60.9-1.0-1.0-1.80.40.50.4
Pavlov. Cond. latency score1.11.85.3-1.6-1.4-1.7-1.21.21.7-2.32.30.61.6-1.41.41.61.6-0.0-0.1-0.60.8-1.0-1.1-1.80.20.50.3
Pavlov. Cond. lever contacts1.21.75.1-1.7-1.5-1.7-1.31.31.7-2.32.30.81.6-1.31.31.61.60.10.1-0.30.8-0.8-0.7-1.70.10.4-0.0
Pavlov. Cond. magazine entry number0.91.14.01.31.31.31.2-1.2-1.32.0-2.0-0.8-1.31.2-1.2-1.3-1.3-0.5-0.1-0.1-0.00.10.20.80.40.20.2
Pavlov. Cond. intertrial magazine entries1.43.17.4-1.0-0.9-0.4-1.31.30.7-0.20.21.91.4-1.21.21.01.02.22.12.6-2.42.72.72.1-2.5-2.2-2.2
Pavlov. Cond. lever-magazine prob. diff.0.91.34.5-1.3-1.2-1.4-1.01.01.4-2.12.10.41.3-1.11.11.31.3-0.2-0.3-0.70.9-1.0-1.0-1.70.30.50.3
Pavlov. Cond. response bias1.52.16.9-2.0-1.8-1.8-1.31.31.8-2.62.60.91.6-1.51.51.71.70.0-0.0-0.30.9-0.8-0.7-1.80.30.40.3
Time in closed arm before self-admin0.10.20.60.80.80.70.6-0.6-0.60.5-0.5-0.5-0.10.4-0.4-0.4-0.4-0.6-0.3-0.30.5-0.2-0.20.20.10.20.0
Time in closed arm after self-admin0.10.10.2-0.00.30.3-0.10.10.1-0.10.10.30.3-0.20.20.30.30.20.30.3-0.20.30.30.3-0.4-0.4-0.4
Time in open arm before self-admin0.10.20.60.10.20.30.3-0.3-0.20.3-0.3-0.4-0.60.4-0.4-0.3-0.3-0.5-0.3-0.50.4-0.4-0.4-0.30.50.40.8
Time in open arm after self-admin0.30.40.90.60.30.00.4-0.4-0.50.1-0.1-0.8-0.40.7-0.7-0.7-0.7-0.5-0.9-0.90.5-0.7-0.8-0.40.60.80.7
Bone: periosteal estimation0.10.41.1-0.2-0.4-0.20.1-0.1-0.2-1.01.0-0.50.30.3-0.3-0.7-0.7-0.5-0.9-0.60.6-0.6-0.7-0.90.11.00.3
Bone: periosteal perimeter0.20.41.30.1-0.10.20.4-0.4-0.5-0.50.5-0.70.00.7-0.7-1.0-1.0-0.6-1.0-0.50.6-0.6-0.7-0.70.11.10.4
Bone: post-yield work0.20.31.40.1-0.10.60.1-0.1-0.5-0.00.00.2-0.20.1-0.1-0.2-0.20.4-0.00.9-0.61.10.81.2-0.9-0.7-0.9
Progressive ratio test 1 active lever presses0.20.41.7-0.5-0.70.10.0-0.00.10.1-0.10.7-0.4-0.30.30.30.30.50.51.1-1.01.31.11.2-0.1-1.0-0.0
Progressive ratio test 1 breakpoint0.20.31.4-0.4-0.60.10.2-0.2-0.00.2-0.20.6-0.5-0.20.20.20.20.40.41.0-0.91.21.01.10.0-0.90.1
Progressive ratio test 1 inactive lever presses1.12.87.0-1.0-0.9-0.4-0.90.90.70.6-0.62.00.2-1.21.21.21.22.02.32.5-2.52.62.62.3-1.7-2.4-1.9
Progressive ratio test 2 active lever presses0.50.72.7-0.5-0.8-0.0-0.30.30.2-0.10.10.9-0.2-0.50.50.50.50.90.71.3-1.41.61.51.5-0.6-1.3-0.5
Progressive ratio test 2 breakpoint0.60.82.5-0.7-1.0-0.2-0.40.40.4-0.30.31.0-0.0-0.60.60.60.61.00.71.3-1.41.61.51.4-0.6-1.3-0.5
Progressive ratio test 2 inactive lever presses0.61.93.5-1.3-1.4-1.1-1.31.31.2-0.60.61.70.8-1.41.41.41.41.71.61.8-1.91.81.71.2-1.3-1.7-1.3
Incentive Sensitization - Responses0.10.41.1-0.5-0.7-0.2-0.50.50.3-0.50.60.60.3-0.50.50.50.50.70.30.7-0.91.01.00.8-0.6-0.9-0.6
Incentive Sensitization - Breakpoint0.30.61.3-0.7-0.9-0.4-0.70.70.5-0.70.70.90.5-0.70.70.70.70.90.50.9-1.01.21.10.8-0.7-1.0-0.7
Sum of active levers in priming session hrs 5-62.22.13.91.91.72.01.8-1.8-1.72.0-2.0-1.6-1.81.7-1.7-1.7-1.7-1.1-1.1-0.70.6-0.4-0.40.70.30.50.6
Progressive ratio0.20.62.20.40.41.21.2-1.2-0.70.8-0.8-0.1-1.50.2-0.2-0.2-0.2-0.8-0.30.20.20.60.30.91.1-0.71.2
Food seeking constrained by brief footshock5.87.216.63.02.73.53.8-3.8-3.23.4-3.4-2.4-4.12.6-2.6-2.6-2.6-2.8-2.0-1.41.4-0.7-0.80.92.80.72.7
Seeking ratio, punishment vs. effort0.61.42.51.51.41.01.1-1.1-1.31.1-1.1-1.6-0.71.6-1.6-1.5-1.5-1.0-1.1-1.21.0-1.2-1.0-0.50.31.40.2
Retroperitoneal fat weight0.41.94.4-0.20.2-0.4-1.31.30.70.4-0.41.41.2-1.21.21.31.31.62.01.7-1.51.71.61.6-2.1-1.9-1.9
Reaction time number correct0.93.15.82.12.02.42.2-2.2-2.12.1-2.1-1.8-2.32.0-2.0-1.9-1.9-1.8-1.5-1.01.1-0.6-0.70.61.10.81.4
Reaction time mean minus median0.21.13.6-1.3-1.5-1.7-1.11.11.1-1.41.40.41.0-0.80.80.40.40.00.2-0.60.7-1.1-1.0-1.90.71.01.0
Reaction time mean minus median AUC0.10.41.3-0.9-1.1-1.2-0.80.80.6-1.11.10.40.8-0.50.50.20.20.30.2-0.20.1-0.3-0.4-1.00.00.50.3
Reaction time num false alarms0.10.10.5-0.3-0.5-0.10.2-0.20.1-0.60.6-0.30.50.3-0.3-0.2-0.2-0.3-0.5-0.10.2-0.3-0.4-0.5-0.10.70.4
Reaction time num false alarms AUC0.10.10.4-0.2-0.4-0.00.2-0.20.0-0.60.6-0.30.50.4-0.4-0.2-0.2-0.1-0.50.00.0-0.2-0.2-0.3-0.50.60.1
Reaction time trials correct on left0.93.15.82.12.02.42.2-2.2-2.12.1-2.1-1.8-2.32.0-2.0-1.9-1.9-1.8-1.5-1.01.1-0.6-0.70.61.10.81.4
Reaction time trials on left0.93.05.72.12.02.42.2-2.2-2.12.1-2.1-1.8-2.22.0-2.0-1.9-1.9-1.7-1.4-0.91.0-0.5-0.60.61.00.71.3
Reaction time mean0.40.83.5-0.4-0.6-1.2-0.70.70.6-1.11.1-0.31.0-0.20.2-0.1-0.1-0.2-0.4-1.10.8-1.4-1.3-1.90.51.30.8
Reaction time mean AUC0.41.04.4-0.4-0.5-1.2-0.60.60.5-1.01.0-0.40.8-0.00.0-0.2-0.2-0.4-0.6-1.41.0-1.7-1.6-2.10.71.51.0
Median of all reaction times0.40.62.30.10.0-0.7-0.30.30.2-0.70.7-0.60.70.2-0.2-0.3-0.3-0.3-0.6-1.20.8-1.4-1.3-1.50.41.30.6
Reaction time omissions0.10.20.6-0.4-0.6-0.6-0.60.60.2-0.10.10.30.70.1-0.1-0.3-0.30.70.50.4-0.50.10.1-0.3-0.60.3-0.6
Reaction time false alarm rate0.60.82.0-1.2-1.2-1.0-0.90.91.0-1.41.40.81.4-0.70.70.80.80.80.40.7-0.70.40.4-0.2-1.0-0.2-0.7
Reaction time premature initiation rate0.71.13.91.62.01.31.0-1.0-1.22.0-2.0-0.8-1.00.9-0.9-0.8-0.8-0.80.0-0.50.6-0.20.00.70.2-0.1-0.3
Reaction time premature initiations1.23.79.22.73.02.62.2-2.2-2.43.0-3.0-1.8-2.22.0-2.0-1.9-1.9-1.7-0.8-1.01.1-0.5-0.31.00.80.40.4
Std. dev. reaction times0.20.73.1-0.7-0.9-1.2-0.70.70.5-0.90.9-0.10.8-0.20.2-0.2-0.2-0.2-0.2-0.90.8-1.2-1.2-1.80.71.40.9
Reaction time trials completed0.93.05.72.12.02.42.2-2.2-2.12.1-2.1-1.8-2.22.0-2.0-1.9-1.9-1.7-1.4-0.91.0-0.5-0.60.61.00.71.3
Reaction time trials AUC0.93.05.82.12.12.42.2-2.2-2.12.0-2.0-1.8-2.22.0-2.0-1.9-1.9-1.8-1.5-1.01.1-0.6-0.70.61.10.81.3
Run reversals in cocaine runway, females0.10.10.40.40.00.40.3-0.3-0.4-0.20.2-0.30.00.4-0.4-0.3-0.30.0-0.60.1-0.20.20.00.3-0.1-0.1-0.1
Run reversals in cocaine runway, males1.01.14.0-1.8-2.0-1.6-0.80.81.3-1.81.81.00.0-1.01.01.01.00.4-0.00.2-0.30.1-0.1-0.81.0-0.11.0
Latency to leave start box in cocaine runway1.11.52.61.01.10.71.0-1.0-1.00.7-0.7-1.4-1.11.1-1.1-1.2-1.2-1.5-1.3-1.61.6-1.5-1.4-1.01.31.51.2
Latency to leave start box in cocaine runway, F0.60.81.70.50.60.30.7-0.7-0.60.5-0.5-1.0-0.90.8-0.8-0.8-0.8-1.1-0.9-1.11.1-1.2-1.1-1.01.31.21.1
Latency to leave start box in cocaine runway, M1.11.12.41.01.20.91.0-1.0-1.00.4-0.4-1.2-0.80.9-0.9-0.9-0.9-1.4-1.2-1.51.6-1.2-1.2-0.70.81.20.9
Std. dev. time between licks in bursts0.81.55.1-1.2-1.2-2.2-2.22.21.4-1.21.30.62.3-0.50.50.60.61.40.80.2-0.6-0.4-0.2-1.4-1.10.6-1.1
Total sessions with >9 infusions0.30.40.8-0.8-0.7-0.5-0.40.40.7-0.80.80.80.6-0.80.80.90.90.20.50.4-0.10.50.40.1-0.2-0.6-0.3
Short access day 1 total inactive lever presses2.55.011.8-3.2-3.4-2.5-2.22.22.8-2.72.72.71.6-2.72.72.72.71.81.71.9-1.51.41.5-0.0-0.7-1.7-0.6
Short access day 10 total inactive lever presses0.10.61.3-0.7-0.4-0.2-0.50.50.60.1-0.11.10.2-0.70.70.90.90.81.21.1-0.81.11.10.9-0.7-1.1-1.0
Short access day 1 total infusions0.30.61.3-1.1-1.0-0.4-0.40.40.7-1.01.01.10.4-1.01.01.01.00.40.60.8-0.30.90.80.4-0.3-0.9-0.1
Short access day 10 total infusions0.81.33.9-1.9-2.0-1.5-0.90.91.5-1.81.81.10.5-1.31.31.31.30.40.30.3-0.10.0-0.0-0.80.5-0.30.5
Short access total infusions0.81.22.9-1.6-1.7-1.1-0.80.81.3-1.31.31.40.4-1.41.41.41.40.70.80.9-0.70.90.80.3-0.1-1.10.0
Short access day 1 locomotion0.50.93.2-1.0-0.8-0.8-0.40.41.0-1.81.80.20.7-0.70.70.70.7-0.7-0.5-0.81.3-1.0-1.0-1.60.60.70.7
Short access day 10 total locomotion0.10.31.4-0.6-0.5-0.7-0.50.50.7-1.21.20.31.0-0.50.50.60.60.1-0.1-0.10.2-0.3-0.4-0.7-0.00.2-0.2
Short access total locomotion0.60.92.7-1.3-1.1-1.2-0.80.81.2-1.61.60.81.2-1.11.11.11.10.00.2-0.00.5-0.3-0.3-1.00.00.0-0.1
One hour access (0.3 mA shock)1.51.84.3-1.9-2.1-1.3-1.11.11.6-1.41.41.70.6-1.71.71.71.71.01.11.3-1.01.21.10.4-0.2-1.40.1
Compulsive drug intake1.82.64.1-1.8-1.6-1.6-1.81.82.0-1.51.51.91.8-1.81.82.02.01.71.71.4-1.31.01.20.1-1.5-1.4-1.2
One hour access (shock baseline)0.10.10.8-0.4-0.7-0.10.3-0.30.1-0.20.20.2-0.7-0.20.20.10.1-0.3-0.2-0.00.10.20.00.10.9-0.10.9
Social response proportion3.03.87.32.62.62.62.3-2.3-2.62.6-2.6-2.0-1.82.7-2.7-2.3-2.3-1.5-1.2-0.80.8-0.3-0.40.80.40.80.7
Social responses1.01.43.31.81.81.50.9-0.9-1.61.7-1.7-1.1-0.41.8-1.8-1.5-1.5-0.3-0.4-0.20.10.10.20.6-0.60.5-0.4
Social time0.30.41.3-0.5-0.6-1.1-1.01.00.7-0.90.90.21.1-0.30.30.30.30.70.2-0.2-0.3-0.4-0.4-0.9-0.70.6-0.4
Soleus weight3.911.520.32.82.62.84.1-4.1-2.92.0-2.0-3.7-3.83.1-3.1-3.0-3.0-4.5-3.8-3.84.1-3.4-3.5-1.84.23.04.3
Bone: stiffness0.71.21.9-1.3-1.3-1.1-1.21.21.2-1.41.41.21.4-1.11.11.31.31.00.91.0-0.70.80.8-0.0-1.4-0.6-1.1
Tibialis anterior weight2.38.119.71.31.21.42.8-2.8-1.3-0.10.1-2.8-2.71.7-1.7-1.4-1.4-4.1-3.6-4.04.3-3.7-3.8-2.94.22.94.4
Time to tail flick, vehicle, before self-admin2.93.57.3-1.7-1.7-1.1-1.41.41.6-0.30.32.40.9-1.91.91.91.92.32.42.6-2.72.42.51.7-1.5-2.5-1.6
Time to tail flick, vehicle, after self-admin0.81.76.11.20.71.81.7-1.7-1.32.5-2.5-0.5-2.30.9-0.9-1.0-1.0-0.70.00.4-0.40.70.71.60.9-0.40.9
Time to tail flick, test, before self-admin1.41.62.5-1.2-1.1-1.3-1.51.51.3-1.41.41.41.6-1.31.31.41.41.51.01.1-1.20.90.90.3-1.4-1.0-1.1
Time to tail flick, test, after self-admin0.80.92.80.70.60.6-0.00.0-0.41.3-1.30.30.50.2-0.2-0.2-0.20.81.11.2-1.21.21.31.5-1.7-1.0-1.4
Delta time to tail flick, vehicle, before/after SA1.21.33.21.30.91.51.4-1.4-1.41.7-1.7-1.0-1.81.1-1.1-1.2-1.2-1.1-0.6-0.40.5-0.0-0.00.80.90.30.8
Delta time to tail flick, test, before/after SA1.51.85.52.01.92.01.4-1.4-1.82.3-2.3-1.1-0.91.5-1.5-1.6-1.6-0.6-0.20.10.10.40.51.4-0.6-0.0-0.7
Tibia length7.420.631.1-5.4-4.7-5.1-5.45.45.3-4.54.55.35.5-5.65.65.45.44.64.73.7-3.22.82.9-0.0-3.2-3.1-3.1
Ambulatory time before self-admin0.20.61.6-0.1-0.1-0.40.3-0.30.0-0.50.5-0.7-0.40.2-0.2-0.2-0.2-0.8-1.0-1.21.1-1.3-1.3-1.31.31.00.8
Ambulatory time after self-admin1.72.75.51.11.31.11.8-1.8-1.30.6-0.6-1.7-1.91.2-1.2-1.2-1.2-2.2-1.9-2.02.2-1.8-1.9-1.12.41.62.0
Bone: tissue strength0.30.31.1-0.5-0.8-0.9-1.01.00.5-0.70.70.11.0-0.10.10.20.20.60.10.0-0.2-0.2-0.2-0.6-0.60.3-0.4
Total heroin consumption0.30.42.2-0.4-0.8-0.20.5-0.50.1-0.30.3-0.2-1.10.0-0.0-0.1-0.1-0.6-0.7-0.60.4-0.5-0.6-0.51.50.41.3
Bone: trabecular number0.20.51.1-0.8-1.1-0.7-0.80.80.5-0.91.00.70.8-0.70.70.50.50.80.40.6-0.60.60.40.2-0.7-0.2-0.4
Bone: trabecular spacing0.71.01.71.11.00.81.2-1.2-0.90.8-0.8-1.2-0.81.0-1.0-1.0-1.0-1.3-0.9-1.31.1-1.2-1.2-0.60.91.10.7
Bone: trabecular thickness1.52.13.4-1.8-1.7-1.4-1.81.81.7-1.71.71.70.9-1.61.61.81.81.61.01.4-1.11.31.20.4-0.8-1.1-1.0
Bone: trabecular tissue density0.40.71.60.70.60.51.0-1.0-0.60.2-0.2-0.9-0.80.6-0.6-0.5-0.5-1.2-1.0-1.21.2-1.0-1.0-0.81.10.71.0
Water consumed over 24 hours0.10.10.6-0.6-0.5-0.3-0.10.10.2-0.70.80.2-0.1-0.30.30.50.5-0.1-0.3-0.10.2-0.00.0-0.30.40.10.6
Number of responses in last shaping day0.20.30.80.30.30.60.7-0.7-0.50.1-0.1-0.6-0.90.5-0.5-0.6-0.6-0.6-0.9-0.40.4-0.4-0.5-0.10.60.50.4