Nudt14

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Nudt14 0.19 0.12 4.4e-05 0.17 0.17 0.16 0.18 8.3e-05 7.3e-05 1.3e-04 5.0e-05
2 Liver mRNA stability Nudt14 0.12 0.09 1.4e-13 0.1 0.11 0.1 0.11 1.0e-11 1.2e-12 1.8e-11 2.6e-12
3 RMTg gene expression Nudt14 0.22 0.13 4.2e-06 0.13 0.18 0.12 0.12 2.0e-04 1.1e-05 4.6e-04 4.0e-04
4 OFC gene expression Nudt14 0.15 0.11 1.5e-03 0.09 0.1 0.09 0.1 3.9e-03 2.2e-03 4.6e-03 2.9e-03
5 PL mRNA stability Nudt14 0.07 0.05 7.7e-11 0.11 0.1 0.1 0.11 7.9e-12 5.0e-11 2.6e-11 9.6e-12
6 LHb gene expression Nudt14 0.64 0.26 1.6e-07 0.3 0.27 0.25 0.28 7.1e-08 3.5e-07 1.0e-06 1.9e-07
7 Adipose mRNA stability Nudt14 0.18 0.1 0.0e+00 0.14 0.16 0.14 0.14 7.0e-15 3.3e-17 5.8e-15 5.0e-15
8 BLA mRNA stability Nudt14 0.24 0.14 4.4e-10 0.15 0.17 0.16 0.16 2.1e-08 2.1e-09 7.9e-09 1.0e-08
9 Brain mRNA stability Nudt14 0.19 0.08 0.0e+00 0.29 0.28 0.28 0.29 5.4e-27 1.4e-26 1.5e-26 4.7e-27
10 PL gene expression Nudt14 0.18 0.08 0.0e+00 0.31 0.32 0.31 0.31 3.6e-35 9.4e-36 4.1e-35 5.2e-35
11 pVTA mRNA stability Nudt14 0.13 0.1 1.8e-05 0.08 0.09 0.04 0.05 3.2e-04 1.5e-04 6.8e-03 3.1e-03
12 BLA gene expression Nudt14 0.31 0.13 0.0e+00 0.38 0.36 0.36 0.36 9.6e-22 1.9e-20 2.3e-20 2.1e-20
13 Brain gene expression Nudt14 0.34 0.13 0.0e+00 0.38 0.39 0.39 0.38 4.4e-37 2.7e-38 1.1e-38 1.1e-37
14 pVTA gene expression Nudt14 0.21 0.11 1.5e-11 0.23 0.24 0.22 0.22 1.8e-10 7.8e-11 9.2e-10 6.9e-10
15 NAcc mRNA stability Nudt14 0.07 0.04 9.1e-11 0.09 0.09 0.09 0.09 7.8e-11 1.9e-10 6.8e-11 5.0e-10
16 Liver gene expression Nudt14 0.06 0.04 5.1e-08 0.06 0.05 0.04 0.05 7.2e-07 1.1e-06 8.3e-06 7.7e-06
17 NAcc gene expression Nudt14 0.11 0.07 3.1e-14 0.09 0.12 0.11 0.12 9.5e-11 5.6e-14 1.3e-12 3.5e-13
18 IL mRNA stability Nudt14 0.16 0.11 2.2e-04 0.12 0.1 0.06 0.09 8.5e-04 2.1e-03 1.2e-02 3.9e-03
19 IL gene expression Nudt14 0.19 0.12 7.2e-05 0.18 0.14 0.15 0.14 3.6e-05 3.3e-04 1.9e-04 3.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.00.00.10.20.10.20.2-0.2-0.20.20.10.20.20.2-0.2-0.30.2-0.2-0.20.2-0.1-0.1
Area under the delay curve1.41.52.1-1.4-1.2-1.3-1.31.51.3-1.5-1.3-1.2-1.2-1.31.30.9-1.20.60.7-1.11.31.2
BMI with tail1.55.06.9-2.2-1.9-2.2-2.12.02.1-2.3-2.1-2.3-2.4-2.42.32.4-2.42.32.6-2.62.01.9
BMI without tail0.81.62.3-1.2-1.2-1.3-1.21.01.2-1.4-1.3-1.4-1.3-1.41.51.5-1.31.21.4-1.21.11.0
Body weight1.77.39.33.03.02.82.8-3.0-2.92.62.82.52.62.5-2.5-2.52.6-2.8-2.32.3-2.9-2.9
Weight adjusted by age0.10.20.40.40.50.40.4-0.4-0.50.20.30.30.30.3-0.6-0.60.4-0.5-0.40.3-0.3-0.3
Bone surface0.30.61.0-0.8-0.9-0.7-0.80.70.6-0.7-0.8-0.6-0.6-0.70.60.6-0.60.80.8-0.50.91.0
Bone volume0.20.40.7-0.7-0.8-0.6-0.70.50.6-0.6-0.7-0.6-0.5-0.50.60.6-0.50.60.7-0.30.70.8
Breakpoint value in progressive ratio session0.00.00.1-0.10.20.10.2-0.1-0.10.40.20.20.10.2-0.2-0.20.00.2-0.2-0.10.20.3
Number of licking bursts1.31.52.0-1.4-1.2-1.2-1.21.11.3-1.3-1.3-1.2-1.2-1.21.11.2-1.21.11.0-1.01.31.4
Context. condit. distance diff. score3.54.25.02.11.92.02.0-1.8-2.02.02.02.12.12.1-2.2-2.22.1-2.2-2.02.2-2.0-1.9
Locomotion velocity, session 10.20.20.40.30.60.50.5-0.4-0.40.30.40.50.30.3-0.5-0.70.3-0.6-0.60.2-0.2-0.4
Locomotion distance, session 10.20.20.6-0.6-0.1-0.4-0.40.40.6-0.4-0.4-0.3-0.5-0.50.20.2-0.60.40.2-0.80.50.5
Locomotion velocity, session 20.40.50.8-0.8-0.4-0.6-0.60.80.6-0.9-0.7-0.6-0.7-0.80.60.4-0.70.40.5-0.70.90.8
Locomotion distance, session 20.71.01.3-1.2-0.9-1.0-1.01.11.1-1.1-1.0-0.9-1.0-1.10.90.9-1.01.01.1-1.01.11.1
Locomotion velocity, session 30.10.10.5-0.5-0.1-0.1-0.20.50.1-0.1-0.30.1-0.2-0.2-0.2-0.2-0.30.2-0.1-0.30.70.7
Locomotion distance, session 30.10.10.5-0.5-0.1-0.2-0.30.50.3-0.3-0.4-0.1-0.3-0.30.0-0.1-0.30.10.0-0.30.60.7
Stereotopy head waving bouts, day 30.00.00.10.20.20.20.2-0.3-0.30.30.20.20.30.2-0.2-0.20.2-0.1-0.10.3-0.0-0.1
Stereotopy head waving duration, day 30.00.00.10.20.10.20.2-0.3-0.30.20.20.20.30.3-0.2-0.10.3-0.1-0.20.4-0.0-0.1
Locomotion velocity, session 70.10.10.30.40.20.20.3-0.4-0.40.50.30.30.30.4-0.3-0.00.2-0.0-0.30.1-0.3-0.3
Locomotion distance, session 70.81.11.2-1.1-1.0-1.0-1.01.11.1-1.0-1.1-1.0-1.0-1.01.01.1-1.01.00.9-1.01.11.1
Stereotopy head waving bouts, day 72.73.03.41.71.61.71.7-1.8-1.71.81.71.81.81.8-1.7-1.71.8-1.7-1.91.8-1.5-1.6
Stereotopy head waving duration, day 71.82.12.71.51.31.51.5-1.6-1.41.61.51.51.51.6-1.5-1.41.5-1.3-1.61.4-1.3-1.4
Locomotion velocity, session 82.53.03.61.91.81.81.8-1.5-1.81.81.81.81.71.8-1.8-1.81.7-1.7-1.51.6-1.7-1.7
Locomotion distance, session 80.40.61.20.70.80.80.8-0.5-0.70.80.80.90.80.8-1.1-0.90.8-0.8-0.70.7-0.7-0.5
Degree of sensitization distance0.20.20.7-0.2-0.6-0.5-0.40.20.3-0.4-0.4-0.5-0.4-0.40.60.8-0.40.60.6-0.40.20.1
Degree of sensitization stereotypy1.11.31.51.11.01.11.1-1.2-1.11.21.11.11.11.2-1.0-1.11.1-1.0-1.21.1-1.1-1.1
Conditioned locomotion1.92.22.61.51.51.51.5-1.6-1.41.41.51.41.51.4-1.4-1.61.5-1.5-1.51.4-1.4-1.5
Cocaine response after cond. corrected0.00.00.10.10.30.10.1-0.1-0.00.30.20.2-0.00.0-0.2-0.2-0.10.0-0.1-0.3-0.1-0.1
Cocaine response after cond. not corrected0.20.21.0-0.4-0.1-0.4-0.40.50.5-0.4-0.3-0.4-0.6-0.60.40.2-0.70.50.5-1.00.30.3
Cocaine response before conditioning2.42.83.7-1.6-1.6-1.7-1.71.71.6-1.9-1.7-1.8-1.8-1.81.91.5-1.71.61.8-1.81.41.3
Saline control response0.00.00.2-0.00.20.20.20.0-0.20.20.10.30.20.2-0.3-0.40.2-0.2-0.40.20.20.2
Bone: connectivity density0.40.60.90.80.80.80.8-0.8-0.90.80.70.80.80.8-0.8-1.00.8-0.8-0.70.7-0.7-0.7
Bone: cortical apparent density4.05.37.12.42.22.32.3-2.2-2.22.02.22.22.32.2-2.2-2.32.4-2.7-2.42.5-2.3-2.3
Bone: cortical area0.10.20.50.20.10.30.3-0.3-0.40.60.30.50.50.6-0.6-0.40.5-0.2-0.50.7-0.10.1
Bone: cortical porosity0.20.20.40.50.30.40.4-0.4-0.40.40.40.40.50.5-0.3-0.50.5-0.4-0.30.6-0.4-0.4
Bone: cortical porosity0.20.20.30.60.40.50.5-0.5-0.60.50.50.40.50.5-0.4-0.50.5-0.4-0.30.5-0.5-0.6
Bone: cortical thickness0.71.11.61.00.91.01.0-1.0-0.91.31.01.21.11.2-1.2-1.01.1-0.9-1.21.1-1.0-0.8
Bone: cortical thickness0.50.61.00.60.60.70.6-0.6-0.60.70.60.90.80.8-0.8-0.90.8-0.9-1.01.0-0.5-0.4
Bone: cortical tissue density3.95.27.02.32.22.32.2-2.2-2.12.02.22.22.32.2-2.2-2.32.4-2.7-2.32.5-2.3-2.3
Condit. Reinf. active minus inactive responses0.20.20.5-0.5-0.3-0.5-0.50.70.4-0.4-0.5-0.4-0.5-0.50.40.4-0.60.40.2-0.70.50.5
Condit. Reinf. active-inactive response ratio1.41.52.3-1.2-1.2-1.3-1.21.21.1-1.1-1.2-1.3-1.3-1.31.31.3-1.41.31.1-1.51.11.1
Condit. Reinf. active responses0.10.10.30.30.60.30.3-0.2-0.40.30.30.40.20.2-0.2-0.40.2-0.5-0.5-0.0-0.3-0.3
Condit. Reinf. inactive responses2.22.63.51.51.81.71.7-1.5-1.41.61.61.81.61.6-1.7-1.81.6-1.9-1.81.5-1.4-1.3
Incentive salience index mean0.00.00.20.20.40.20.2-0.0-0.30.20.20.20.00.0-0.1-0.2-0.1-0.2-0.3-0.3-0.2-0.2
Condit. Reinf. lever presses0.30.40.70.80.80.60.7-0.7-0.70.70.70.60.50.6-0.5-0.50.5-0.6-0.60.2-0.8-0.8
Condit. Reinf. active minus inactive responses0.30.40.80.70.70.70.7-0.6-0.70.40.60.60.60.5-0.7-0.90.7-0.8-0.60.7-0.5-0.6
Condit. Reinf. active-inactive response ratio0.10.10.20.20.20.30.3-0.4-0.20.10.20.20.30.2-0.4-0.40.4-0.4-0.10.5-0.1-0.2
Condit. Reinf. active responses0.00.00.10.10.10.00.00.1-0.1-0.3-0.1-0.1-0.1-0.20.0-0.2-0.0-0.20.0-0.00.0-0.1
Condit. Reinf. inactive responses0.20.30.5-0.5-0.3-0.5-0.50.60.5-0.7-0.5-0.6-0.6-0.70.70.4-0.60.30.4-0.70.30.3
Condit. Reinf. lever presses2.12.93.5-1.8-1.7-1.7-1.71.71.7-1.9-1.8-1.7-1.7-1.81.81.4-1.71.71.7-1.61.71.6
Condit. Reinf. lever reinforcers received0.00.00.10.00.10.00.00.1-0.1-0.3-0.1-0.1-0.0-0.20.0-0.20.0-0.3-0.10.00.0-0.0
Conditioned reinforcement - actives0.80.81.20.70.90.90.9-0.8-0.80.80.80.90.90.9-1.0-1.01.0-1.0-1.11.0-0.7-0.6
Conditioned reinforcement - inactives0.40.41.00.40.80.70.6-0.6-0.60.40.60.60.60.5-0.6-0.90.6-0.9-1.00.5-0.6-0.5
Conditioned locomotion0.00.00.20.00.0-0.0-0.00.00.0-0.0-0.0-0.1-0.1-0.10.0-0.1-0.10.2-0.1-0.2-0.50.1
Patch foraging indifference point 0 sec6.911.214.53.53.53.43.4-3.4-3.53.33.33.33.33.3-3.3-3.83.3-3.2-3.23.1-3.0-3.1
Patch foraging indifference point AUC7.99.111.13.23.33.13.1-3.1-3.03.13.13.12.92.9-3.1-3.22.8-2.8-3.02.4-3.0-3.0
Delay disc. indifference point, 0s delay0.40.50.90.70.70.60.6-0.5-0.70.60.60.70.60.6-0.6-0.90.6-0.9-0.90.6-0.6-0.6
Delay disc. indifference point, 16s delay1.61.62.3-1.3-1.3-1.3-1.41.31.4-1.5-1.4-1.3-1.3-1.41.21.1-1.30.91.0-1.21.11.1
Delay disc. indifference point, 2s delay4.34.86.7-2.5-2.3-2.2-2.22.42.1-2.4-2.3-2.2-2.1-2.22.21.9-2.01.71.8-1.82.62.4
Delay disc. indifference point, 24s delay1.31.21.8-1.2-1.1-1.2-1.21.21.3-1.3-1.2-1.1-1.2-1.31.10.8-1.10.60.8-1.11.11.0
Delay disc. indifference point, 4s delay0.50.61.1-1.0-0.7-0.7-0.80.90.8-1.1-0.8-0.7-0.7-0.80.80.6-0.60.20.4-0.51.00.8
Delay disc. indifference point, 8s delay0.50.50.8-0.8-0.6-0.7-0.70.90.8-0.9-0.7-0.7-0.7-0.80.90.4-0.70.20.2-0.60.80.6
Indifference point function ln k0.20.30.90.60.30.50.5-0.4-0.60.40.50.40.60.6-0.5-0.50.7-0.6-0.60.9-0.5-0.5
Indifference point function log k0.20.30.90.60.30.50.5-0.4-0.60.40.50.40.60.6-0.5-0.50.7-0.6-0.60.9-0.5-0.5
Patch foraging total patch changes 0 sec8.413.617.03.93.83.83.8-3.8-3.93.73.73.63.73.6-3.7-4.13.6-3.5-3.53.4-3.4-3.4
Patch foraging total patch changes 12 sec4.05.17.92.22.52.42.3-2.3-2.22.12.22.32.22.1-2.3-2.82.2-2.4-2.42.0-1.9-2.0
Patch foraging total patch changes 18 sec3.03.85.62.02.12.02.0-2.0-2.01.91.92.01.91.9-1.9-2.41.8-1.9-2.11.7-1.7-1.7
Patch foraging total patch changes 24 sec1.62.02.71.61.61.51.5-1.5-1.61.41.41.41.31.3-1.4-1.61.3-1.2-1.31.1-1.3-1.3
Patch foraging total patch changes 6 sec7.511.114.03.53.73.43.5-3.5-3.53.43.43.43.23.2-3.3-3.73.1-3.1-3.32.7-3.1-3.2
Patch foraging time to switch 0 sec12.619.421.8-4.7-4.5-4.5-4.54.44.5-4.3-4.4-4.4-4.4-4.44.54.4-4.44.44.1-4.34.34.2
Patch foraging water rate 0 sec17.528.030.05.55.35.45.4-5.3-5.45.15.25.35.45.3-5.4-5.55.4-5.3-5.05.4-5.0-4.9
Patch foraging water rate 12 sec4.97.511.12.92.92.82.8-2.6-2.72.22.62.72.82.6-2.6-2.52.9-3.3-2.63.0-2.7-2.7
Patch foraging water rate 18 sec3.44.66.02.32.22.22.2-2.1-2.31.82.12.12.22.0-2.3-2.02.2-2.4-1.82.3-1.9-2.0
Patch foraging water rate 24 sec2.53.54.71.92.12.02.0-1.9-1.91.51.81.91.91.7-1.9-1.92.0-2.2-1.41.9-1.8-1.7
Patch foraging water rate 6 sec4.16.06.92.52.52.52.5-2.5-2.42.32.42.42.52.4-2.6-2.42.5-2.6-2.22.5-2.4-2.3
Seeking ratio, delayed vs. immediate footshock0.30.40.60.60.60.60.6-0.6-0.70.70.60.50.70.7-0.8-0.60.6-0.6-0.60.6-0.5-0.5
Distance traveled before self-admin0.80.91.2-0.9-0.8-0.9-1.01.01.0-1.1-1.0-0.9-1.0-1.11.00.6-1.00.81.0-1.10.61.0
Distance traveled after self-admin0.10.10.20.20.10.20.2-0.2-0.20.10.20.20.30.2-0.3-0.40.3-0.5-0.30.4-0.00.1
Extensor digitorum longus weight10.139.943.66.66.16.36.3-6.3-6.36.46.36.56.46.5-6.4-6.26.4-6.3-6.36.4-6.1-6.0
Bone: elastic displacement0.10.10.2-0.2-0.4-0.3-0.30.30.4-0.4-0.3-0.2-0.1-0.20.40.2-0.0-0.10.00.20.10.2
Bone: elastic work0.91.21.6-1.2-1.3-1.1-1.21.11.2-1.3-1.2-1.1-1.0-1.11.21.0-0.90.81.0-0.61.11.1
Bone: endosteal estimation1.73.64.8-2.1-2.2-1.9-2.02.01.8-2.0-2.0-1.9-1.7-1.81.91.8-1.61.91.9-1.32.12.0
Bone: endosteal perimeter0.30.61.1-0.9-0.9-0.7-0.80.80.6-0.7-0.8-0.6-0.6-0.60.60.7-0.61.00.9-0.51.01.1
Epididymis fat weight1.84.15.6-1.9-1.9-2.0-2.01.81.8-1.8-1.9-2.2-2.1-2.12.12.3-2.22.32.1-2.41.71.7
Delta time in closed arm before/after self-admin0.10.10.20.40.40.30.3-0.4-0.30.30.30.20.30.3-0.3-0.40.3-0.30.20.2-0.3-0.2
Delta time in open arm before/after self-admin1.11.11.91.11.01.01.0-1.1-1.11.11.01.11.01.1-1.0-1.11.0-1.0-1.41.0-1.0-0.7
Diff in mean of infusions in LGA sessions0.80.91.70.91.11.01.0-0.9-1.01.31.01.10.91.0-1.1-0.90.8-0.4-1.00.6-0.6-0.7
Delay discount exponential model param1.11.21.81.31.11.11.1-1.3-1.21.31.21.11.11.2-1.1-0.81.0-0.5-0.60.9-1.3-1.1
Extinction: sum of active levers before priming0.00.00.1-0.0-0.0-0.0-0.00.00.00.20.00.1-0.00.1-0.20.0-0.1-0.0-0.3-0.1-0.1-0.1
Active lever presses in extinction session 61.41.41.91.31.11.21.1-1.1-1.11.21.11.21.21.2-1.2-1.11.2-1.0-1.41.3-1.4-1.0
Bone: final force0.20.41.0-0.7-1.0-0.6-0.70.60.5-0.5-0.7-0.5-0.4-0.40.50.6-0.30.70.70.00.80.8
Bone: final moment0.10.20.7-0.5-0.8-0.4-0.50.40.3-0.3-0.5-0.3-0.1-0.10.30.4-0.10.50.50.30.60.6
Food consumed during 24 hour testing period0.91.11.31.11.11.11.1-1.0-1.11.01.01.11.11.0-1.1-1.01.0-1.1-1.11.0-0.9-0.9
Glucose0.00.00.1-0.2-0.3-0.1-0.1-0.00.1-0.1-0.2-0.00.10.00.00.00.10.0-0.20.30.30.2
Heart weight0.20.30.6-0.6-0.7-0.5-0.50.50.4-0.4-0.6-0.5-0.4-0.40.60.6-0.40.80.5-0.20.70.8
Delay discount hyperbolic model param1.51.62.31.51.31.31.3-1.5-1.31.51.31.31.31.4-1.3-0.91.2-0.6-0.71.1-1.5-1.3
Intermittent access intake day 1-15 change1.51.41.8-1.2-1.1-1.2-1.21.31.2-1.2-1.2-1.1-1.3-1.31.11.2-1.31.11.0-1.31.21.1
Intermittent access intake escalation1.41.41.6-1.2-1.1-1.2-1.21.31.2-1.1-1.2-1.2-1.2-1.21.11.3-1.31.11.0-1.31.11.1
Intermittent access intake escalation 20.20.20.5-0.5-0.4-0.4-0.40.40.4-0.2-0.4-0.3-0.4-0.30.30.4-0.40.40.2-0.40.70.4
Intermitt. access day 1 inactive lever presses3.03.34.51.91.91.81.8-1.7-1.71.61.71.71.71.7-1.8-1.91.8-2.1-2.11.7-1.9-1.9
Intermitt. access day 15 inactive lever presses0.40.41.00.60.60.60.6-0.5-0.50.40.50.50.60.6-0.7-0.60.7-1.0-1.00.7-0.6-0.5
Intermitt. access escalation Index0.00.00.1-0.20.00.10.00.0-0.0-0.1-0.00.10.1-0.0-0.1-0.10.1-0.00.10.10.40.3
Intermittent access day 1 total infusions0.10.10.70.50.40.30.3-0.3-0.30.40.30.10.20.3-0.5-0.20.2-0.1-0.20.1-0.8-0.4
Intermittent access day 15 total infusions0.80.91.3-0.8-0.9-1.0-1.01.01.0-0.9-1.0-1.1-1.0-1.00.71.1-1.11.01.0-1.10.30.9
Intermittent access terminal intake (last 3 days)1.21.31.7-1.1-1.1-1.1-1.11.21.1-1.1-1.2-1.2-1.2-1.20.91.1-1.21.21.0-1.30.81.1
Intermittent access total infusions0.10.10.2-0.1-0.2-0.2-0.20.30.2-0.2-0.2-0.4-0.3-0.30.00.4-0.30.40.2-0.4-0.40.2
Intermittent access day 1 locomotion0.00.00.1-0.0-0.0-0.1-0.00.00.00.0-0.0-0.2-0.1-0.1-0.10.1-0.10.30.2-0.2-0.40.1
Intermittent access day 15 total locomotion0.10.10.30.1-0.1-0.2-0.20.20.2-0.2-0.2-0.3-0.2-0.20.10.3-0.20.30.4-0.3-0.50.1
Intermittent access total locomotion0.00.10.30.20.30.20.3-0.2-0.30.30.20.10.20.2-0.4-0.10.10.0-0.1-0.0-0.5-0.1
Intermittent access standard deviation0.40.41.4-0.4-0.3-0.6-0.60.60.6-0.5-0.5-0.7-0.8-0.80.50.5-0.90.70.7-1.20.00.4
Left kidney weight3.18.79.93.23.03.03.0-3.1-3.03.03.03.03.03.0-2.9-3.03.0-2.8-2.52.9-3.0-2.9
Right kidney weight1.44.04.62.12.02.12.1-2.2-2.02.02.02.12.12.1-2.0-1.82.1-1.8-1.52.1-2.0-1.8
Cocaine induced anxiety0.30.30.70.50.50.60.6-0.5-0.50.50.50.60.70.6-0.5-0.60.7-0.5-0.60.9-0.4-0.3
Post-drug Anxiety0.30.30.50.40.50.60.6-0.6-0.60.60.50.60.60.6-0.6-0.60.7-0.5-0.50.7-0.2-0.2
Baseline Anxiety0.60.61.0-0.8-0.7-0.8-0.80.80.8-0.7-0.8-0.7-0.9-0.80.80.7-0.90.80.9-1.00.90.8
Tail length5.115.517.64.23.94.04.0-4.0-3.93.83.93.84.04.0-3.8-3.64.1-4.0-4.04.1-3.9-3.8
Length with tail9.936.341.16.46.16.16.1-6.1-6.05.96.16.06.06.0-5.9-5.96.0-6.1-5.95.9-6.0-5.9
Length without tail6.614.316.24.03.93.83.8-3.8-3.83.83.93.83.73.7-3.8-4.03.7-3.8-3.63.4-3.8-3.8
Times rat made contact with spout0.20.20.50.40.70.60.5-0.3-0.50.50.50.60.40.4-0.6-0.50.4-0.5-0.60.2-0.3-0.3
Lifetime Intake0.10.10.3-0.3-0.4-0.4-0.40.40.4-0.4-0.4-0.6-0.4-0.40.20.5-0.40.40.4-0.4-0.20.3
Liver weight, left2.84.55.22.32.22.12.2-2.2-2.12.12.22.12.12.1-2.0-2.12.1-2.2-1.92.1-2.2-2.3
Liver weight, right0.71.12.01.11.41.11.1-1.2-1.11.11.11.00.90.9-1.0-1.10.8-1.1-1.10.5-1.0-1.1
Locomotor activity0.10.20.30.50.40.40.4-0.5-0.40.30.40.30.40.3-0.4-0.40.4-0.5-0.40.4-0.4-0.5
Locomotor testing distance0.10.10.20.30.30.30.3-0.3-0.30.20.30.20.30.2-0.3-0.30.3-0.5-0.40.3-0.3-0.3
Locomotor testing rearing2.03.14.2-1.9-1.5-1.7-1.71.81.7-1.7-1.8-1.8-1.8-1.91.51.5-1.91.61.5-2.01.91.7
Locomotion in novel chamber2.73.34.91.81.71.81.8-1.9-1.61.41.71.81.91.8-1.8-1.52.0-2.2-1.92.2-1.6-1.7
Locomotion in novel chamber post-restriction0.20.30.4-0.5-0.6-0.5-0.50.50.5-0.6-0.5-0.4-0.5-0.50.70.6-0.40.50.6-0.30.50.4
Fecal boli incidents, locomotor time 10.10.10.5-0.3-0.3-0.4-0.30.20.4-0.1-0.3-0.3-0.5-0.40.40.3-0.60.40.2-0.70.2-0.1
Change in fecal boli incidents, locomotor task1.51.42.11.21.31.31.2-1.1-1.41.01.21.01.21.1-1.2-1.11.3-1.4-1.01.4-1.0-1.2
Time >=10cm from walls, locomotor time 13.43.45.42.22.21.91.9-1.9-1.92.02.01.91.71.7-1.8-1.81.5-1.5-1.21.1-2.3-2.2
Bouts of movement, locomotor time 11.11.21.7-1.3-1.1-1.1-1.11.11.2-1.0-1.1-1.1-1.1-1.11.11.0-1.21.20.5-1.21.21.1
Total resting periods, locomotor time 11.31.51.9-1.4-1.3-1.3-1.31.21.3-1.1-1.3-1.3-1.2-1.21.21.2-1.31.20.7-1.31.11.1
Rest time, locomotor task time 10.50.50.8-0.8-0.7-0.7-0.80.80.7-0.9-0.9-0.9-0.7-0.80.60.7-0.70.40.3-0.60.70.6
Distance moved, locomotor task time 11.01.12.2-1.0-1.1-1.1-1.10.91.2-1.0-1.0-1.0-1.0-1.01.01.0-1.01.21.5-0.90.71.0
Vertical activity count, locomotor time 10.10.10.5-0.3-0.3-0.3-0.30.20.4-0.3-0.2-0.2-0.3-0.30.50.3-0.20.40.7-0.10.20.3
Time >=10cm from walls, locomotor time 22.83.03.61.91.81.81.8-1.8-1.91.91.81.81.71.7-1.7-1.71.6-1.4-1.81.4-1.7-1.5
Bouts of movement, locomotor time 20.10.10.4-0.5-0.6-0.3-0.30.40.3-0.4-0.4-0.4-0.0-0.10.00.40.10.1-0.30.50.40.5
Total resting periods, locomotor time 20.20.20.5-0.6-0.7-0.4-0.50.60.4-0.6-0.6-0.6-0.2-0.30.20.5-0.10.2-0.10.30.50.6
Rest time, locomotor task time 20.10.10.3-0.1-0.2-0.3-0.30.60.4-0.5-0.3-0.4-0.3-0.40.20.1-0.3-0.2-0.1-0.2-0.1-0.0
Distance moved, locomotor task time 20.40.51.0-0.8-0.7-0.6-0.60.50.7-0.5-0.6-0.5-0.6-0.60.60.6-0.71.01.0-0.70.80.9
Vertical activity count, locomotor time 20.10.10.20.20.20.20.2-0.4-0.10.30.20.30.30.3-0.1-0.10.30.20.10.2-0.2-0.2
Light reinforcement 10.00.00.10.10.10.10.1-0.1-0.20.00.10.10.10.1-0.0-0.40.1-0.10.00.1-0.1-0.2
Light reinforcement 21.01.42.0-1.0-1.2-1.2-1.21.01.2-1.1-1.0-1.3-1.3-1.21.21.4-1.31.31.3-1.40.70.7
Bone: marrow area1.63.64.8-2.1-2.2-1.9-2.02.01.8-2.0-2.0-1.9-1.7-1.81.81.8-1.61.81.9-1.32.12.0
Bone: maximum diameter0.20.40.8-0.7-0.7-0.6-0.60.70.6-0.4-0.6-0.4-0.5-0.50.40.5-0.50.70.5-0.40.80.9
Bone: maximum force0.00.10.3-0.2-0.5-0.2-0.20.10.0-0.1-0.2-0.10.00.00.10.20.00.40.30.30.30.4
Bone: maximum moment0.00.00.20.0-0.30.0-0.0-0.1-0.20.2-0.00.10.20.3-0.10.00.20.20.10.50.10.2
Mean time between licks in bursts0.60.81.1-0.9-0.8-0.9-0.90.91.0-1.0-0.8-1.0-0.9-0.91.00.7-0.90.80.9-0.90.70.6
Mean num. licks in bursts1.72.02.41.61.51.51.5-1.2-1.51.51.51.51.41.4-1.3-1.41.3-1.3-1.31.1-1.4-1.5
Cd content in liver0.50.61.10.70.80.80.7-0.6-0.70.40.70.70.80.6-0.7-0.90.8-1.1-0.80.9-0.7-0.7
Co content in liver0.91.11.80.91.11.11.0-0.8-0.91.01.01.21.11.1-1.2-1.01.1-1.2-1.31.1-0.9-0.7
Cu content in liver2.63.23.7-1.9-1.7-1.8-1.81.81.7-1.7-1.7-1.7-1.8-1.81.71.9-1.81.91.8-1.81.71.9
Fe content in liver1.11.31.8-1.2-1.3-1.2-1.21.21.1-1.0-1.1-1.2-1.1-1.11.21.2-1.11.41.3-1.01.11.2
K content in liver1.31.32.01.31.41.11.2-1.2-1.01.11.31.11.01.0-1.1-1.01.0-1.1-0.90.8-1.4-1.3
Mg content in liver0.20.20.60.60.50.40.5-0.5-0.40.30.50.30.40.4-0.3-0.30.4-0.5-0.20.4-0.7-0.7
Mn content in liver0.20.20.50.50.10.30.3-0.5-0.40.40.40.30.50.5-0.3-0.20.5-0.4-0.20.7-0.5-0.5
Na content in liver0.00.00.10.10.20.10.1-0.20.00.20.20.0-0.00.00.00.1-0.10.1-0.0-0.2-0.3-0.2
Rb content in liver0.20.20.50.30.50.50.4-0.2-0.30.30.30.50.50.4-0.6-0.60.5-0.7-0.50.6-0.3-0.2
Se content in liver0.00.00.1-0.00.1-0.0-0.00.10.1-0.1-0.0-0.0-0.1-0.10.10.0-0.1-0.10.1-0.2-0.10.0
Sr content in liver0.20.10.4-0.6-0.2-0.3-0.30.60.6-0.5-0.4-0.1-0.3-0.40.0-0.1-0.2-0.00.1-0.20.60.7
Zn content in liver0.10.10.2-0.4-0.2-0.2-0.30.30.4-0.3-0.3-0.2-0.2-0.20.20.2-0.10.10.0-0.00.30.3
Bone: minimum diameter0.30.61.40.70.40.80.7-0.7-0.90.90.70.80.91.0-0.9-0.71.0-0.6-0.61.2-0.5-0.4
Time in familiar zone, hab. session 10.00.00.1-0.2-0.2-0.1-0.10.10.20.1-0.10.0-0.00.0-0.1-0.0-0.10.2-0.1-0.00.30.3
Time in novel zone, hab. session 10.90.91.3-0.9-0.8-0.9-0.91.10.9-1.2-0.9-1.0-1.0-1.11.00.9-0.90.71.1-0.90.80.8
Total zone transitions, hab. session 10.60.91.2-1.0-1.1-1.0-1.00.80.9-1.0-1.0-1.0-0.9-0.90.91.0-0.81.01.1-0.70.90.9
Total locomotion distance, hab. session 10.00.00.1-0.0-0.2-0.1-0.1-0.00.0-0.2-0.1-0.10.10.00.20.10.1-0.00.20.40.1-0.0
Locomotion velocity, hab. session 10.30.40.80.60.40.60.6-0.7-0.60.50.50.50.70.6-0.5-0.40.7-0.6-0.50.9-0.6-0.6
Time in familiar zone, hab. session 20.60.61.00.80.90.80.8-1.0-0.71.00.90.90.70.8-0.9-0.60.6-0.6-0.60.4-0.8-0.7
Time in novel zone, hab. session 21.21.21.6-1.2-1.2-1.1-1.11.31.0-1.3-1.2-1.1-1.1-1.11.21.0-1.00.91.0-0.91.21.1
Total zone transitions, hab. session 20.10.20.4-0.5-0.2-0.4-0.40.40.5-0.4-0.4-0.3-0.5-0.50.30.2-0.50.40.3-0.60.50.5
Total locomotion distance, hab. session 20.10.20.40.30.50.50.4-0.3-0.30.30.30.50.50.4-0.5-0.60.5-0.6-0.50.5-0.2-0.2
Locomotion velocity, hab. session 20.30.40.50.50.60.60.6-0.5-0.50.50.50.70.60.6-0.6-0.70.7-0.7-0.70.7-0.4-0.4
Novel to familiar place preference ratio0.90.91.4-1.1-1.0-1.0-1.01.21.1-0.9-1.0-0.8-1.0-1.00.90.8-1.00.70.6-0.91.01.1
Novelty place preference1.11.11.7-1.2-1.1-1.1-1.11.31.2-1.1-1.2-0.9-1.0-1.11.00.9-1.00.80.7-0.91.11.2
Time in novel zone, NPP test0.40.40.7-0.8-0.7-0.7-0.70.80.7-0.7-0.7-0.5-0.6-0.70.60.5-0.70.40.3-0.60.70.8
Total zone transitions, NPP test0.50.81.40.81.20.90.9-0.9-0.80.70.81.00.80.7-1.0-1.10.7-1.1-1.00.5-0.7-0.7
Total locomotion distance, NPP test0.40.50.90.70.80.70.7-0.7-0.60.50.70.70.70.6-0.7-0.80.7-0.9-0.80.6-0.7-0.7
Locomotion velocity, NPP test0.20.20.50.50.60.50.5-0.4-0.40.30.40.50.50.4-0.5-0.60.5-0.7-0.60.5-0.5-0.5
Intraocular pressure0.40.50.7-0.7-0.8-0.7-0.70.80.7-0.8-0.8-0.7-0.7-0.70.70.8-0.60.60.4-0.50.70.7
Delta distance traveled before/after self-admin0.30.40.80.30.30.60.6-0.6-0.60.60.60.60.70.7-0.6-0.40.7-0.6-0.80.90.2-0.2
Delta ambulatory time before/after self-admin0.91.02.00.80.70.90.9-1.0-1.01.00.91.01.11.1-1.0-0.81.2-1.2-1.21.4-0.3-0.7
Parametrial fat weight0.10.20.3-0.5-0.4-0.4-0.40.40.6-0.5-0.5-0.4-0.5-0.50.40.5-0.50.40.5-0.50.50.5
Pavlov. Cond. lever latency0.00.00.2-0.2-0.3-0.0-0.10.10.2-0.0-0.10.00.10.1-0.1-0.00.20.0-0.00.40.30.2
Pavlov. Cond. magazine entry latency0.00.00.20.1-0.2-0.1-0.1-0.1-0.00.30.1-0.1-0.00.1-0.00.4-0.10.30.2-0.0-0.2-0.1
Pavlov. Cond. change in total contacts0.00.00.10.30.20.20.2-0.2-0.30.30.20.10.10.2-0.1-0.10.1-0.1-0.1-0.0-0.3-0.2
Pavlov. Cond. index score0.00.00.10.20.0-0.10.0-0.1-0.10.20.1-0.1-0.10.00.10.3-0.20.20.1-0.3-0.3-0.2
Pavlov. Cond. latency score0.00.00.10.20.0-0.00.0-0.1-0.10.10.1-0.1-0.1-0.00.10.2-0.10.10.0-0.3-0.2-0.2
Pavlov. Cond. lever contacts0.20.20.6-0.3-0.3-0.4-0.40.40.3-0.4-0.4-0.5-0.5-0.50.50.5-0.60.50.5-0.80.20.3
Pavlov. Cond. magazine entry number0.00.10.2-0.3-0.0-0.1-0.20.30.3-0.4-0.3-0.0-0.1-0.20.2-0.2-0.1-0.20.00.00.40.3
Pavlov. Cond. intertrial magazine entries8.610.512.33.33.33.33.2-2.9-3.23.23.23.43.33.2-3.3-3.33.2-3.5-3.43.1-3.0-2.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.2-0.0-0.00.0-0.1-0.10.20.1-0.1-0.10.00.10.3-0.10.20.1-0.2-0.3-0.2
Pavlov. Cond. response bias0.10.10.20.40.30.20.2-0.3-0.30.40.30.10.10.2-0.20.10.10.0-0.1-0.1-0.5-0.4
Pavlov. Cond. lever latency3.44.55.52.22.12.12.1-2.1-2.12.32.22.22.22.2-2.2-1.92.1-2.0-2.12.0-2.1-2.0
Pavlov. Cond. magazine entry latency3.84.35.3-2.3-1.8-2.0-2.02.12.1-2.2-2.1-2.0-2.2-2.22.01.7-2.22.02.0-2.32.22.2
Pavlov. Cond. change in total contacts6.69.110.5-3.2-3.0-3.0-3.03.03.0-3.0-3.1-3.0-3.0-3.02.92.7-3.03.13.0-2.93.23.1
Pavlov. Cond. index score5.06.47.5-2.7-2.3-2.5-2.52.62.5-2.7-2.6-2.5-2.6-2.72.52.1-2.62.52.5-2.62.62.5
Pavlov. Cond. latency score4.35.46.3-2.5-2.1-2.3-2.32.32.3-2.4-2.3-2.3-2.4-2.52.31.9-2.42.32.3-2.52.42.3
Pavlov. Cond. lever contacts3.64.95.7-2.4-2.1-2.2-2.22.32.3-2.4-2.3-2.2-2.3-2.32.21.9-2.22.12.2-2.22.22.1
Pavlov. Cond. magazine entry number3.54.35.62.41.82.02.0-2.1-2.12.12.11.92.12.2-1.9-1.62.1-2.0-1.92.2-2.3-2.3
Pavlov. Cond. intertrial magazine entries4.86.27.62.72.42.52.5-2.4-2.52.32.52.32.52.4-2.4-2.32.6-2.7-2.52.6-2.6-2.6
Pavlov. Cond. lever-magazine prob. diff.5.77.38.5-2.9-2.5-2.7-2.72.72.7-2.8-2.8-2.7-2.8-2.82.72.3-2.82.62.6-2.82.82.7
Pavlov. Cond. response bias3.75.16.0-2.4-2.1-2.2-2.22.32.2-2.4-2.3-2.3-2.3-2.42.21.9-2.32.12.3-2.32.32.2
Time in closed arm before self-admin8.39.410.6-3.1-3.1-3.1-3.13.33.1-3.2-3.1-3.1-3.1-3.23.23.0-3.12.82.9-3.02.82.8
Time in closed arm after self-admin7.17.39.2-2.7-2.7-2.7-2.82.82.8-3.0-2.8-2.8-2.7-2.82.92.6-2.62.32.9-2.42.42.4
Time in open arm before self-admin6.06.57.42.42.72.72.7-2.7-2.52.42.62.62.62.5-2.6-2.52.7-2.6-2.42.6-2.1-2.4
Time in open arm after self-admin10.912.013.83.73.53.63.6-3.6-3.63.73.63.53.53.6-3.5-3.33.4-3.0-3.43.2-3.3-3.2
Bone: periosteal estimation0.51.01.9-1.2-1.4-1.0-1.11.20.9-1.0-1.1-0.9-0.8-0.80.80.9-0.71.00.9-0.41.31.3
Bone: periosteal perimeter0.00.10.2-0.2-0.4-0.2-0.20.20.0-0.0-0.2-0.1-0.1-0.00.00.2-0.10.40.20.00.40.4
Bone: post-yield work2.02.73.31.71.41.71.6-1.8-1.81.81.61.61.81.8-1.7-1.61.7-1.4-1.51.8-1.4-1.5
Progressive ratio test 1 active lever presses0.10.10.3-0.1-0.3-0.3-0.30.30.3-0.4-0.4-0.5-0.3-0.40.20.3-0.30.10.1-0.3-0.20.1
Progressive ratio test 1 breakpoint0.10.10.4-0.2-0.3-0.4-0.40.40.4-0.5-0.4-0.7-0.4-0.50.30.3-0.40.20.1-0.4-0.10.1
Progressive ratio test 1 inactive lever presses2.02.23.01.41.51.51.5-1.4-1.51.21.41.21.51.4-1.5-1.51.5-1.7-1.71.6-1.4-1.4
Progressive ratio test 2 active lever presses0.00.00.1-0.1-0.1-0.2-0.20.20.2-0.3-0.2-0.3-0.2-0.30.00.3-0.20.10.2-0.2-0.10.3
Progressive ratio test 2 breakpoint0.00.00.10.1-0.1-0.1-0.10.10.1-0.2-0.1-0.2-0.1-0.1-0.10.2-0.1-0.00.1-0.1-0.30.1
Progressive ratio test 2 inactive lever presses0.00.00.1-0.1-0.00.0-0.00.10.0-0.3-0.1-0.20.0-0.1-0.10.10.1-0.3-0.20.2-0.20.1
Incentive Sensitization - Responses0.20.20.3-0.4-0.4-0.4-0.40.40.4-0.5-0.4-0.4-0.4-0.40.30.4-0.30.30.5-0.30.50.6
Incentive Sensitization - Breakpoint0.10.10.3-0.4-0.3-0.3-0.30.40.4-0.5-0.4-0.4-0.3-0.40.30.4-0.30.30.4-0.20.40.5
Sum of active levers in priming session hrs 5-60.20.20.3-0.6-0.4-0.5-0.40.50.5-0.3-0.4-0.3-0.5-0.40.30.3-0.50.50.3-0.60.50.6
Progressive ratio1.71.92.8-1.4-1.6-1.4-1.51.41.5-1.7-1.5-1.5-1.3-1.41.41.6-1.21.21.4-0.81.21.1
Food seeking constrained by brief footshock0.00.00.2-0.0-0.10.0-0.00.2-0.0-0.0-0.10.00.10.1-0.1-0.10.1-0.3-0.50.30.0-0.0
Seeking ratio, punishment vs. effort1.11.32.11.01.21.21.2-1.0-1.21.31.21.31.11.2-1.2-1.31.0-1.2-1.40.9-0.9-0.9
Retroperitoneal fat weight0.00.10.3-0.3-0.2-0.3-0.30.30.2-0.3-0.3-0.3-0.4-0.40.30.4-0.40.30.1-0.50.30.3
Reaction time number correct4.46.36.92.62.42.52.5-2.5-2.62.52.52.52.52.5-2.5-2.62.5-2.5-2.62.5-2.4-2.4
Reaction time mean minus median0.00.00.1-0.2-0.1-0.2-0.20.20.2-0.3-0.2-0.2-0.2-0.30.40.2-0.2-0.10.0-0.20.00.0
Reaction time mean minus median AUC0.00.00.1-0.1-0.1-0.2-0.20.20.2-0.2-0.2-0.1-0.1-0.20.30.1-0.1-0.2-0.2-0.1-0.00.0
Reaction time num false alarms2.02.73.31.81.61.61.7-1.7-1.71.61.71.61.71.7-1.5-1.51.7-1.6-1.61.6-1.7-1.6
Reaction time num false alarms AUC2.23.03.82.01.61.71.7-1.8-1.81.71.81.61.71.8-1.6-1.51.8-1.6-1.61.8-1.8-1.8
Reaction time trials correct on left4.46.36.92.62.42.52.5-2.5-2.62.52.52.52.52.5-2.5-2.62.5-2.5-2.62.5-2.4-2.4
Reaction time trials on left4.46.36.92.62.42.52.5-2.5-2.62.52.52.52.52.5-2.5-2.62.5-2.5-2.62.5-2.4-2.4
Reaction time mean2.23.04.3-1.8-1.8-1.8-1.81.81.9-1.9-1.7-1.8-1.7-1.81.92.1-1.71.41.7-1.51.41.5
Reaction time mean AUC1.31.82.7-1.4-1.4-1.4-1.41.41.5-1.5-1.3-1.4-1.4-1.41.51.6-1.31.01.2-1.11.11.1
Median of all reaction times2.02.74.1-1.7-1.8-1.7-1.71.71.8-1.8-1.7-1.6-1.6-1.71.82.0-1.51.31.6-1.31.41.4
Reaction time omissions0.81.11.81.11.01.11.0-1.0-1.00.81.01.11.11.0-0.8-0.91.2-1.3-1.11.3-1.1-1.1
Reaction time false alarm rate0.10.20.30.60.40.40.4-0.5-0.50.30.40.30.40.4-0.3-0.10.4-0.3-0.20.5-0.5-0.5
Reaction time premature initiation rate0.20.20.50.40.30.40.4-0.3-0.30.40.40.50.40.4-0.4-0.70.5-0.6-0.70.5-0.5-0.4
Reaction time premature initiations2.23.14.31.81.61.71.7-1.7-1.71.71.71.81.81.8-1.7-2.11.8-1.8-2.01.8-1.7-1.6
Std. dev. reaction times1.31.92.5-1.4-1.4-1.4-1.41.41.5-1.6-1.4-1.4-1.4-1.41.61.6-1.31.01.1-1.11.11.2
Reaction time trials completed4.46.36.92.62.42.52.5-2.5-2.62.52.52.52.52.5-2.5-2.62.5-2.5-2.62.5-2.4-2.4
Reaction time trials AUC4.66.67.32.72.52.62.5-2.6-2.62.52.52.62.62.6-2.6-2.72.6-2.6-2.62.6-2.4-2.4
Run reversals in cocaine runway, females3.13.03.9-1.7-1.9-1.8-1.81.91.8-1.8-1.8-1.8-1.7-1.71.82.0-1.71.61.6-1.51.31.4
Run reversals in cocaine runway, males0.10.10.4-0.4-0.2-0.2-0.20.10.1-0.3-0.2-0.3-0.2-0.20.30.2-0.10.20.4-0.10.60.3
Latency to leave start box in cocaine runway1.11.12.3-1.3-1.1-1.1-1.11.21.0-1.1-1.1-1.0-1.0-1.01.00.8-1.00.80.8-0.91.51.4
Latency to leave start box in cocaine runway, F0.30.30.4-0.5-0.5-0.5-0.50.60.5-0.5-0.5-0.5-0.6-0.50.50.3-0.60.50.6-0.60.30.6
Latency to leave start box in cocaine runway, M1.11.14.6-1.4-1.0-0.9-1.01.10.9-1.0-1.0-0.8-0.9-0.90.80.7-0.90.70.4-0.82.11.3
Std. dev. time between licks in bursts0.10.10.20.20.20.30.2-0.3-0.30.30.20.40.30.3-0.4-0.40.3-0.2-0.40.3-0.0-0.0
Total sessions with >9 infusions0.10.10.3-0.1-0.2-0.2-0.20.10.2-0.3-0.2-0.5-0.2-0.20.10.4-0.20.20.3-0.2-0.3-0.0
Short access day 1 total inactive lever presses0.00.00.2-0.1-0.1-0.2-0.20.20.2-0.4-0.2-0.3-0.2-0.30.20.1-0.2-0.10.2-0.2-0.3-0.0
Short access day 10 total inactive lever presses0.20.20.70.40.50.40.4-0.3-0.30.10.30.20.30.2-0.3-0.50.4-0.9-0.70.4-0.5-0.5
Short access day 1 total infusions0.00.00.1-0.0-0.1-0.1-0.10.00.1-0.2-0.1-0.3-0.0-0.1-0.00.20.0-0.20.10.1-0.3-0.1
Short access day 10 total infusions0.20.30.5-0.4-0.5-0.5-0.50.60.5-0.6-0.6-0.7-0.6-0.60.40.6-0.60.50.6-0.6-0.00.3
Short access total infusions0.80.91.4-1.0-1.0-0.9-0.90.90.9-1.0-1.0-1.2-0.9-1.00.81.1-0.90.91.1-0.80.50.8
Short access day 1 locomotion0.40.40.7-0.6-0.6-0.7-0.70.70.7-0.7-0.7-0.8-0.7-0.70.70.5-0.70.40.6-0.70.20.4
Short access day 10 total locomotion0.00.00.10.10.20.10.1-0.1-0.10.00.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.2-0.3-0.0-0.2
Short access total locomotion0.00.00.2-0.0-0.0-0.1-0.10.10.1-0.3-0.2-0.4-0.2-0.30.10.1-0.20.10.2-0.3-0.4-0.1
One hour access (0.3 mA shock)0.60.71.10.90.90.80.8-0.8-0.80.80.80.70.80.8-0.9-0.90.7-0.8-1.00.6-1.0-0.7
Compulsive drug intake0.70.71.10.81.00.90.9-1.0-0.91.01.00.90.80.9-0.8-1.00.8-0.7-0.70.6-0.6-0.8
One hour access (shock baseline)0.10.10.3-0.3-0.4-0.4-0.40.50.4-0.4-0.4-0.4-0.4-0.40.20.4-0.40.3-0.1-0.3-0.00.5
Social response proportion0.50.51.1-0.6-0.8-0.7-0.70.50.8-1.0-0.6-0.9-0.7-0.70.81.0-0.50.61.1-0.40.40.4
Social responses0.60.71.1-0.9-0.9-0.8-0.80.70.8-1.0-0.9-1.1-0.8-0.80.91.0-0.80.80.8-0.60.90.8
Social time0.10.10.3-0.1-0.4-0.2-0.20.10.2-0.5-0.2-0.3-0.0-0.10.40.50.1-0.20.20.40.0-0.0
Soleus weight2.47.09.02.82.82.72.7-2.5-2.73.02.72.92.62.7-2.8-2.62.4-2.3-2.72.2-2.5-2.4
Bone: stiffness0.81.31.91.10.91.21.1-1.1-1.21.31.01.31.31.3-1.4-1.31.3-1.0-1.11.4-0.8-0.7
Tibialis anterior weight1.03.34.41.71.81.81.8-1.6-1.72.01.82.11.81.9-2.1-2.01.8-1.7-2.01.7-1.5-1.4
Time to tail flick, vehicle, before self-admin2.82.84.21.71.91.71.7-1.6-1.61.61.71.71.51.5-1.6-1.81.5-2.0-2.01.3-1.5-1.8
Time to tail flick, vehicle, after self-admin1.01.01.41.01.21.11.1-1.1-1.11.11.11.01.01.0-0.9-1.11.0-1.0-1.00.8-0.8-1.1
Time to tail flick, test, before self-admin0.10.10.3-0.4-0.5-0.4-0.40.40.4-0.4-0.4-0.4-0.3-0.30.30.3-0.30.40.1-0.20.60.2
Time to tail flick, test, after self-admin5.55.76.72.62.52.42.5-2.5-2.42.42.52.42.32.4-2.2-2.32.3-2.3-2.22.1-2.3-2.5
Delta time to tail flick, vehicle, before/after SA0.20.20.40.40.20.40.4-0.5-0.50.60.50.40.50.6-0.4-0.30.5-0.0-0.20.5-0.3-0.2
Delta time to tail flick, test, before/after SA5.85.26.52.52.52.32.4-2.3-2.42.32.42.32.22.2-2.1-2.32.2-2.4-1.92.0-2.4-2.3
Tibia length0.10.30.60.70.50.50.6-0.7-0.70.40.60.40.50.5-0.4-0.60.5-0.6-0.30.5-0.7-0.8
Ambulatory time before self-admin1.11.21.8-1.3-0.8-1.0-1.01.11.0-1.1-1.0-0.9-1.2-1.21.00.7-1.21.11.2-1.31.21.2
Ambulatory time after self-admin0.20.20.8-0.6-0.5-0.4-0.40.40.4-0.5-0.5-0.4-0.4-0.40.40.1-0.40.30.4-0.30.90.8
Bone: tissue strength0.30.30.6-0.5-0.8-0.6-0.60.40.5-0.5-0.6-0.7-0.5-0.50.60.7-0.40.70.8-0.30.50.5
Total heroin consumption2.63.14.01.81.91.81.8-1.8-1.92.01.81.91.71.8-1.9-1.71.6-1.5-1.71.5-1.6-1.5
Bone: trabecular number0.30.40.60.70.60.60.6-0.7-0.70.60.60.70.70.6-0.6-0.80.7-0.7-0.70.7-0.6-0.5
Bone: trabecular spacing0.00.10.2-0.2-0.3-0.2-0.20.20.3-0.2-0.2-0.3-0.2-0.20.30.5-0.20.20.1-0.10.00.0
Bone: trabecular thickness0.10.10.10.30.40.30.3-0.3-0.30.20.30.20.20.2-0.2-0.30.2-0.3-0.20.2-0.4-0.4
Bone: trabecular tissue density0.00.00.00.00.00.00.00.00.10.10.10.10.00.1-0.10.20.0-0.0-0.00.1-0.2-0.1
Water consumed over 24 hours1.01.21.71.11.11.21.1-1.1-1.20.91.01.11.21.1-1.2-1.21.2-1.3-1.11.3-0.9-0.9
Number of responses in last shaping day0.70.70.8-0.7-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.9-0.90.80.9-0.90.90.9-0.80.60.6