Hub : Genes

Nudcd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Nudcd3 0.08 0.04 8.6e-10 0.09 0.1 0.1 0.1 1.3e-08 9.0e-10 8.2e-10 1.6e-09
2 Adipose isoform ratio NM_001419338.1 0.1 0.05 3.3e-14 0.12 0.13 0.13 0.13 1.5e-13 8.3e-14 2.0e-14 2.0e-14
3 Adipose isoform ratio NM_001103362.2 0.35 0.15 0.0e+00 0.26 0.3 0.31 0.3 9.7e-29 2.6e-34 1.0e-34 3.0e-34
4 LHb gene expression Nudcd3 0.38 0.16 2.7e-06 0.09 0.08 0.14 0.2 3.2e-03 5.2e-03 4.4e-04 1.4e-05
5 Adipose alternative polyA NM_001419338.1 0.25 0.12 0.0e+00 0.21 0.26 0.25 0.26 1.4e-22 4.2e-28 6.1e-28 2.0e-28
6 Adipose alternative polyA NM_001103362.2 0.25 0.11 0.0e+00 0.21 0.26 0.25 0.26 1.7e-22 4.4e-28 6.7e-28 3.8e-28
7 Brain mRNA stability Nudcd3 0.16 0.08 4.6e-12 0.11 0.13 0.12 0.12 1.7e-10 4.9e-12 2.6e-11 1.2e-11
8 Adipose mRNA stability Nudcd3 0.02 0.02 1.0e-02 0 0 0 0 2.8e-01 1.2e-01 1.6e-01 3.0e-01
9 BLA gene expression Nudcd3 0.07 0.05 2.9e-03 0.02 0.03 0 0.02 2.2e-02 1.4e-02 2.0e-01 4.8e-02
10 pVTA gene expression Nudcd3 0.16 0.07 0.0e+00 0.22 0.22 0.24 0.24 7.4e-18 1.5e-17 2.8e-19 6.2e-19
11 Liver mRNA stability Nudcd3 0.03 0.02 9.0e-04 0.03 0.02 0.03 0.03 1.7e-04 1.8e-03 8.1e-04 4.4e-04
12 Adipose gene expression Nudcd3 0.2 0.09 0.0e+00 0.14 0.16 0.16 0.16 3.0e-15 1.5e-17 1.6e-17 4.0e-17
13 BLA mRNA stability Nudcd3 0.2 0.11 2.8e-03 0.04 0.05 0.03 0.03 2.2e-03 1.4e-03 1.3e-02 8.8e-03
14 Liver gene expression Nudcd3 0.12 0.06 2.7e-10 0.06 0.08 0.07 0.08 2.7e-07 6.1e-09 2.7e-08 5.5e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.00.00.1-0.20.10.10.20.2-0.20.20.20.3-0.1-0.10.00.2-0.2
Area under the delay curve2.84.46.72.1-2.3-2.0-1.9-2.22.2-1.9-2.1-2.02.32.0-2.61.1-2.2
BMI with tail0.20.51.30.6-1.1-0.9-0.7-0.70.7-0.7-0.8-0.70.60.9-0.4-0.40.6
BMI without tail0.21.32.11.1-1.4-1.3-1.2-1.31.3-1.5-1.2-0.91.11.3-1.0-0.50.0
Body weight1.67.010.42.8-3.2-3.1-2.8-2.92.9-2.8-2.8-2.72.82.6-2.5-0.2-1.0
Weight adjusted by age0.20.41.10.6-0.6-0.5-0.9-0.60.6-0.5-0.6-0.60.61.1-0.80.4-0.8
Bone surface0.00.10.30.5-0.2-0.4-0.4-0.30.4-0.2-0.4-0.50.1-0.10.0-0.4-0.0
Bone volume0.10.10.40.6-0.4-0.5-0.5-0.40.5-0.3-0.4-0.50.20.1-0.1-0.3-0.0
Breakpoint value in progressive ratio session0.20.41.30.6-0.9-0.5-0.9-0.60.5-0.5-0.7-0.70.41.1-0.5-0.10.0
Number of licking bursts1.13.24.72.1-2.0-2.0-2.0-2.02.0-1.5-1.9-2.21.61.9-1.60.2-1.1
Context. condit. distance diff. score2.73.34.6-1.92.12.12.21.9-1.82.11.91.5-1.9-2.11.70.60.7
Locomotion velocity, session 10.30.40.9-0.21.00.50.20.6-0.50.30.50.6-0.7-0.80.8-0.70.5
Locomotion distance, session 10.60.83.8-0.50.20.30.20.4-0.40.20.60.90.70.4-1.01.9-1.9
Locomotion velocity, session 20.70.93.0-0.11.20.20.30.5-0.40.30.30.2-1.3-1.21.5-1.71.4
Locomotion distance, session 20.50.81.9-1.01.10.80.91.1-1.10.71.11.4-0.5-0.70.40.4-0.2
Locomotion velocity, session 31.31.62.4-1.41.41.61.41.4-1.41.41.41.4-0.9-1.20.71.0-0.3
Locomotion distance, session 30.40.40.80.9-0.6-0.7-0.8-0.70.8-0.7-0.7-0.70.60.3-0.3-0.50.3
Stereotopy head waving bouts, day 30.40.41.2-1.00.80.50.80.7-0.70.30.81.1-0.5-0.30.40.0-0.0
Stereotopy head waving duration, day 32.02.53.7-1.91.91.61.81.8-1.81.51.81.9-1.5-1.31.30.20.3
Locomotion velocity, session 70.10.20.30.5-0.2-0.6-0.4-0.40.5-0.4-0.5-0.50.20.1-0.1-0.40.2
Locomotion distance, session 70.10.10.4-0.20.50.20.40.3-0.20.50.20.0-0.4-0.60.40.20.2
Stereotopy head waving bouts, day 70.20.20.6-0.40.70.70.70.4-0.40.50.40.2-0.5-0.80.40.2-0.0
Stereotopy head waving duration, day 70.10.10.2-0.30.40.40.40.3-0.30.20.30.3-0.1-0.4-0.00.4-0.3
Locomotion velocity, session 81.61.94.7-1.02.11.21.51.4-1.21.41.20.9-1.6-2.21.5-0.20.5
Locomotion distance, session 85.37.711.1-3.03.33.13.13.1-3.12.93.13.0-2.6-2.92.40.80.7
Degree of sensitization distance2.62.84.0-1.82.01.72.01.8-1.82.01.81.4-1.9-1.81.60.50.3
Degree of sensitization stereotypy0.00.00.20.10.10.20.2-0.00.10.1-0.1-0.1-0.0-0.4-0.00.2-0.2
Conditioned locomotion0.70.83.7-0.80.10.40.50.5-0.50.30.60.80.60.6-0.91.9-1.7
Cocaine response after cond. corrected0.91.32.11.2-1.2-1.2-1.2-1.31.3-1.0-1.3-1.41.21.3-1.10.2-0.8
Cocaine response after cond. not corrected1.31.82.51.3-1.6-1.4-1.4-1.51.4-1.1-1.4-1.61.41.6-1.40.5-0.9
Cocaine response before conditioning0.10.20.6-0.5-0.10.40.40.4-0.50.50.50.5-0.10.0-0.10.8-0.3
Saline control response0.30.40.9-0.50.90.70.60.6-0.60.50.60.5-0.8-0.90.7-0.30.4
Bone: connectivity density0.10.20.3-0.50.50.40.50.5-0.60.50.50.5-0.5-0.50.40.10.3
Bone: cortical apparent density0.30.40.70.8-0.7-0.6-0.7-0.80.8-0.8-0.8-0.80.50.3-0.4-0.60.1
Bone: cortical area1.83.04.51.9-2.1-1.8-2.0-1.91.8-1.8-1.8-1.61.81.9-1.7-0.1-0.7
Bone: cortical porosity0.00.00.30.1-0.1-0.2-0.3-0.0-0.0-0.1-0.00.0-0.00.60.1-0.2-0.1
Bone: cortical porosity0.10.10.3-0.30.10.20.10.3-0.40.30.30.3-0.10.3-0.00.5-0.5
Bone: cortical thickness1.62.74.31.6-2.1-1.6-1.9-1.71.6-1.6-1.6-1.41.82.0-1.70.3-1.0
Bone: cortical thickness0.70.94.7-0.5-0.00.60.50.5-0.50.70.60.50.30.4-0.72.2-2.0
Bone: cortical tissue density0.30.50.80.9-0.7-0.7-0.7-0.80.8-0.8-0.8-0.80.50.3-0.3-0.70.2
Condit. Reinf. active minus inactive responses0.91.02.21.2-0.8-1.3-1.0-1.11.1-1.1-1.2-1.30.30.4-0.1-1.50.7
Condit. Reinf. active-inactive response ratio0.91.04.2-0.10.60.10.30.3-0.20.40.0-0.4-1.3-1.11.6-1.82.0
Condit. Reinf. active responses0.50.71.31.1-0.6-1.1-0.8-0.90.9-1.0-1.0-0.90.60.4-0.4-0.8-0.1
Condit. Reinf. inactive responses0.81.12.51.0-0.9-0.8-0.9-0.90.9-0.9-0.8-0.71.30.9-1.40.9-1.6
Incentive salience index mean1.52.03.21.6-1.4-1.8-1.5-1.61.6-1.6-1.7-1.61.21.1-1.0-0.8-0.3
Condit. Reinf. lever presses1.31.93.51.2-1.4-1.3-1.2-1.21.2-1.5-1.2-0.81.91.4-1.90.8-1.8
Condit. Reinf. active minus inactive responses0.30.51.6-0.70.80.61.00.6-0.60.60.60.6-0.4-1.30.30.5-0.2
Condit. Reinf. active-inactive response ratio0.10.10.30.1-0.1-0.20.2-0.20.3-0.2-0.2-0.20.5-0.3-0.50.5-0.5
Condit. Reinf. active responses0.50.71.7-1.01.00.81.20.9-0.90.70.91.0-0.7-1.30.60.30.1
Condit. Reinf. inactive responses0.91.31.9-1.21.31.11.21.3-1.31.21.31.2-1.4-1.21.3-0.20.6
Condit. Reinf. lever presses0.30.41.0-0.60.70.61.00.6-0.60.70.60.5-0.4-0.90.20.8-0.6
Condit. Reinf. lever reinforcers received0.40.51.3-0.70.80.71.00.7-0.70.60.70.8-0.5-1.20.40.3-0.0
Conditioned reinforcement - actives0.00.10.40.4-0.3-0.2-0.4-0.20.2-0.6-0.30.00.10.1-0.1-0.70.2
Conditioned reinforcement - inactives0.20.41.01.0-0.6-0.6-0.9-0.60.7-0.8-0.7-0.60.40.4-0.5-0.4-0.3
Conditioned locomotion0.60.92.81.1-0.9-1.1-0.9-1.01.1-1.7-1.0-0.50.8-0.0-0.7-1.20.2
Patch foraging indifference point 0 sec0.82.36.71.9-1.4-1.8-1.5-1.81.8-1.0-1.9-2.60.50.7-0.2-1.31.0
Patch foraging indifference point AUC0.00.10.50.30.3-0.3-0.0-0.00.1-0.2-0.1-0.2-0.3-0.40.4-0.70.2
Delay disc. indifference point, 0s delay1.51.73.21.2-1.8-0.9-1.0-1.21.2-0.4-1.2-1.71.21.5-1.61.6-1.3
Delay disc. indifference point, 16s delay1.31.82.61.5-1.4-1.5-1.4-1.51.5-1.6-1.5-1.31.31.2-1.3-0.4-0.6
Delay disc. indifference point, 2s delay3.53.96.91.6-2.3-1.5-1.6-1.81.7-1.3-1.7-1.82.22.4-2.62.0-2.6
Delay disc. indifference point, 24s delay1.11.82.31.5-1.4-1.4-1.5-1.51.5-1.3-1.5-1.41.51.3-1.40.1-0.8
Delay disc. indifference point, 4s delay4.44.67.72.1-2.3-2.0-1.9-2.22.2-2.0-2.1-2.02.32.2-2.81.3-2.6
Delay disc. indifference point, 8s delay1.01.73.81.1-1.2-1.1-1.0-1.21.2-1.3-1.1-0.81.71.1-1.80.9-1.9
Indifference point function ln k0.10.30.70.1-0.6-0.1-0.3-0.20.2-0.3-0.10.10.80.8-0.80.8-0.8
Indifference point function log k0.10.30.70.1-0.6-0.1-0.3-0.20.2-0.3-0.10.10.80.8-0.80.8-0.8
Patch foraging total patch changes 0 sec0.82.47.01.9-1.3-1.8-1.5-1.81.8-1.0-2.0-2.60.40.6-0.1-1.51.1
Patch foraging total patch changes 12 sec0.91.23.01.3-0.8-1.2-1.0-1.01.1-0.6-1.2-1.70.00.30.3-1.51.3
Patch foraging total patch changes 18 sec0.71.64.91.7-0.7-1.4-0.9-1.31.4-0.7-1.5-2.2-0.1-0.30.4-1.71.3
Patch foraging total patch changes 24 sec0.61.95.3-0.81.61.01.51.0-0.91.50.80.1-2.0-2.32.0-0.91.5
Patch foraging total patch changes 6 sec1.52.55.52.0-1.3-1.9-1.7-1.71.7-1.3-1.9-2.40.50.8-0.1-1.91.1
Patch foraging time to switch 0 sec0.10.40.8-0.90.30.80.70.6-0.70.60.70.8-0.2-0.00.10.80.0
Patch foraging water rate 0 sec0.62.14.11.8-1.1-1.9-1.7-1.51.6-1.5-1.7-1.90.60.7-0.1-2.01.0
Patch foraging water rate 12 sec0.00.10.40.6-0.2-0.3-0.4-0.40.4-0.4-0.4-0.50.2-0.1-0.1-0.3-0.1
Patch foraging water rate 18 sec0.30.72.4-0.1-0.8-0.1-0.2-0.30.2-0.5-0.10.31.30.8-1.51.6-1.5
Patch foraging water rate 24 sec0.10.10.70.20.0-0.3-0.0-0.10.1-0.5-0.10.20.1-0.60.1-0.80.5
Patch foraging water rate 6 sec0.50.71.40.8-0.6-0.9-0.8-0.70.7-1.2-0.6-0.21.10.7-1.0-0.0-1.2
Seeking ratio, delayed vs. immediate footshock0.10.20.9-0.40.0-0.20.30.0-0.0-0.60.30.90.6-0.1-0.60.3-0.6
Distance traveled before self-admin0.00.00.10.30.0-0.1-0.1-0.10.2-0.1-0.2-0.30.00.10.2-0.40.2
Distance traveled after self-admin0.10.20.90.2-0.1-0.2-0.2-0.20.2-0.4-0.3-0.20.50.2-0.70.5-1.0
Extensor digitorum longus weight2.510.014.13.6-3.5-3.8-3.6-3.63.5-3.6-3.5-3.22.83.3-2.1-2.00.3
Bone: elastic displacement0.40.50.8-0.90.50.90.60.8-0.90.80.80.8-0.8-0.40.7-0.00.5
Bone: elastic work0.30.31.10.3-0.9-0.4-0.7-0.50.4-0.4-0.4-0.20.71.0-0.70.4-0.5
Bone: endosteal estimation0.00.00.10.20.0-0.30.0-0.20.3-0.1-0.2-0.30.2-0.2-0.20.2-0.2
Bone: endosteal perimeter0.51.12.11.0-1.2-1.0-0.9-1.21.2-1.2-1.0-0.91.40.8-1.40.6-0.9
Epididymis fat weight0.31.42.91.2-1.7-1.4-1.3-1.31.3-1.2-1.3-1.21.01.3-1.0-0.30.3
Delta time in closed arm before/after self-admin7.57.011.8-3.32.73.13.03.1-3.12.63.13.4-1.9-1.91.12.1-0.8
Delta time in open arm before/after self-admin4.35.17.62.7-2.4-2.6-2.5-2.62.6-2.3-2.6-2.81.71.4-0.8-2.21.5
Diff in mean of infusions in LGA sessions0.10.10.7-0.2-0.20.20.00.1-0.20.10.00.10.10.3-0.60.9-0.6
Delay discount exponential model param3.14.26.5-2.12.22.01.92.2-2.11.92.12.0-2.3-1.92.5-1.12.2
Extinction: sum of active levers before priming0.10.20.90.3-0.2-0.3-0.2-0.20.2-0.5-0.3-0.1-0.2-0.10.1-0.90.9
Active lever presses in extinction session 60.30.31.8-0.4-0.30.5-0.00.4-0.50.30.30.40.20.6-0.71.3-0.7
Bone: final force0.20.41.00.7-0.7-0.8-0.6-0.70.7-0.7-0.6-0.60.20.20.1-1.00.1
Bone: final moment0.30.51.00.8-0.9-0.9-0.8-0.90.9-0.8-0.8-0.70.40.4-0.1-1.00.0
Food consumed during 24 hour testing period0.71.44.01.4-0.6-1.4-1.2-1.21.2-1.3-1.3-1.30.40.50.1-2.01.0
Glucose8.613.650.64.4-1.5-4.1-3.6-3.43.6-3.6-3.9-4.10.20.21.3-7.14.2
Heart weight0.50.83.80.5-0.1-0.5-0.2-0.30.3-0.1-0.5-0.8-0.7-0.81.0-1.82.0
Delay discount hyperbolic model param3.64.77.3-2.22.32.01.92.2-2.22.02.12.0-2.4-2.12.7-1.22.4
Intermittent access intake day 1-15 change0.21.02.81.3-0.6-1.1-0.9-1.11.1-1.1-1.1-1.20.40.00.2-1.70.9
Intermittent access intake escalation0.20.92.31.3-0.6-1.2-0.9-1.11.1-1.1-1.1-1.20.40.10.1-1.50.7
Intermittent access intake escalation 20.20.31.50.70.1-0.6-0.4-0.50.5-0.4-0.5-0.7-0.0-0.20.5-1.20.6
Intermitt. access day 1 inactive lever presses0.00.30.9-0.40.50.50.50.6-0.50.30.50.6-0.2-0.9-0.10.6-0.8
Intermitt. access day 15 inactive lever presses0.42.23.41.7-1.4-1.8-1.6-1.61.7-1.7-1.6-1.61.10.9-0.4-1.80.8
Intermitt. access escalation Index0.10.42.10.4-0.0-0.2-0.2-0.30.3-0.0-0.4-0.7-0.5-0.40.8-1.31.5
Intermittent access day 1 total infusions0.20.53.30.2-0.10.0-0.5-0.00.0-0.3-0.10.10.40.7-1.01.1-1.8
Intermittent access day 15 total infusions0.61.42.71.6-1.1-1.3-1.5-1.31.3-1.4-1.4-1.40.80.9-0.7-1.0-0.1
Intermittent access terminal intake (last 3 days)0.30.61.21.1-0.5-0.8-1.0-0.80.8-0.8-0.9-1.00.30.5-0.0-1.10.3
Intermittent access total infusions0.60.71.41.1-0.8-0.8-1.2-0.80.8-1.0-1.0-0.80.60.9-0.7-0.5-0.3
Intermittent access day 1 locomotion0.20.41.6-0.40.50.60.20.6-0.6-0.30.51.3-0.1-0.2-0.60.7-1.2
Intermittent access day 15 total locomotion0.20.81.81.1-1.1-1.0-1.0-1.01.0-1.3-1.0-0.60.70.4-0.9-0.60.2
Intermittent access total locomotion0.80.92.01.2-0.9-0.9-1.3-1.01.0-1.4-1.0-0.60.90.8-1.1-0.4-0.5
Intermittent access standard deviation0.31.42.4-1.11.51.01.01.3-1.30.91.31.5-1.3-1.11.5-0.90.9
Left kidney weight0.10.72.00.5-0.9-0.5-0.8-0.60.5-0.8-0.5-0.11.31.0-1.40.9-1.2
Right kidney weight0.10.72.10.2-1.2-0.3-0.6-0.40.3-0.5-0.4-0.11.21.2-1.41.3-0.9
Cocaine induced anxiety1.23.15.22.1-1.9-1.8-2.3-2.02.0-2.0-1.9-1.81.31.6-0.8-1.70.9
Post-drug Anxiety2.42.74.11.9-2.0-1.8-2.0-1.91.8-1.6-1.9-1.91.41.4-1.2-0.70.4
Baseline Anxiety0.10.21.6-0.5-0.20.10.60.2-0.30.40.20.10.1-0.2-0.61.3-0.6
Tail length1.79.112.73.3-3.0-3.3-3.5-3.43.4-3.6-3.3-2.93.13.1-2.7-0.9-1.3
Length with tail2.29.612.33.5-3.3-3.5-3.4-3.53.5-3.5-3.4-3.13.23.0-2.8-0.6-1.5
Length without tail0.31.53.01.3-1.7-1.4-1.2-1.41.3-1.0-1.4-1.51.31.1-1.20.2-0.4
Times rat made contact with spout2.42.79.0-0.11.70.50.41.0-0.91.10.60.1-2.2-2.02.7-2.63.0
Lifetime Intake0.50.61.20.9-0.8-0.7-1.1-0.70.7-0.9-0.8-0.60.60.9-0.6-0.4-0.3
Liver weight, left0.30.51.3-0.80.40.70.50.8-0.90.60.91.1-0.00.2-0.11.0-0.6
Liver weight, right0.81.43.8-1.50.81.51.11.4-1.50.91.51.9-0.4-0.20.11.2-0.2
Locomotor activity0.30.52.20.7-0.1-0.7-0.7-0.60.6-0.3-0.6-1.0-0.3-0.00.7-1.51.0
Locomotor testing distance0.30.71.10.8-0.9-0.9-0.8-0.90.9-0.6-0.8-0.90.70.8-0.70.3-1.0
Locomotor testing rearing0.52.03.61.8-1.3-1.9-1.6-1.61.7-1.4-1.6-1.80.80.9-0.4-1.40.5
Locomotion in novel chamber2.63.57.2-2.01.52.42.02.1-2.12.72.01.5-1.6-1.30.72.6-0.6
Locomotion in novel chamber post-restriction0.92.63.7-1.71.61.91.91.8-1.91.81.91.9-1.2-1.40.71.5-0.7
Fecal boli incidents, locomotor time 10.00.10.5-0.70.30.40.10.4-0.40.10.40.6-0.10.20.2-0.10.2
Change in fecal boli incidents, locomotor task0.30.41.70.40.4-0.50.2-0.10.2-0.2-0.2-0.4-0.3-1.00.7-1.30.9
Time >=10cm from walls, locomotor time 10.20.30.7-0.60.30.60.40.6-0.60.80.60.4-0.5-0.50.40.50.3
Bouts of movement, locomotor time 10.20.31.50.6-0.3-0.5-0.0-0.50.60.1-0.6-1.2-0.2-0.50.3-0.40.1
Total resting periods, locomotor time 10.10.10.40.2-0.0-0.20.3-0.20.20.2-0.2-0.6-0.4-0.60.5-0.50.3
Rest time, locomotor task time 10.00.10.2-0.10.30.00.20.2-0.10.00.20.3-0.3-0.40.3-0.40.0
Distance moved, locomotor task time 10.10.40.90.6-0.6-0.7-0.6-0.70.7-1.0-0.7-0.30.80.5-0.6-0.40.2
Vertical activity count, locomotor time 10.00.10.30.4-0.3-0.2-0.5-0.30.3-0.4-0.4-0.30.30.6-0.2-0.30.2
Time >=10cm from walls, locomotor time 20.20.72.1-0.80.60.80.60.7-0.80.50.91.20.1-0.3-0.31.2-1.4
Bouts of movement, locomotor time 20.62.28.80.9-1.0-1.0-0.5-1.21.3-1.4-1.0-0.61.91.0-2.21.6-3.0
Total resting periods, locomotor time 20.51.97.01.0-0.9-1.1-0.4-1.31.3-1.4-1.1-0.81.80.8-2.01.3-2.7
Rest time, locomotor task time 20.20.31.4-0.40.30.10.40.3-0.30.30.30.2-0.8-0.40.9-0.91.2
Distance moved, locomotor task time 20.10.20.4-0.40.40.40.40.3-0.30.30.40.5-0.0-0.5-0.10.6-0.6
Vertical activity count, locomotor time 20.10.31.5-0.50.30.70.20.5-0.50.70.60.5-0.10.1-0.21.2-0.8
Light reinforcement 10.10.30.90.6-0.4-0.4-0.3-0.60.6-0.7-0.5-0.50.7-0.1-0.80.3-1.0
Light reinforcement 20.61.46.70.4-0.8-0.5-0.4-0.60.6-0.7-0.4-0.01.60.7-2.02.0-2.6
Bone: marrow area0.00.00.10.10.1-0.20.1-0.10.20.0-0.1-0.20.1-0.3-0.20.3-0.3
Bone: maximum diameter2.54.97.32.7-2.4-2.6-2.5-2.62.6-2.5-2.6-2.51.81.7-1.5-1.30.1
Bone: maximum force0.10.30.40.6-0.6-0.6-0.6-0.60.6-0.6-0.5-0.50.50.3-0.4-0.2-0.5
Bone: maximum moment0.20.50.70.7-0.8-0.8-0.7-0.80.8-0.8-0.7-0.70.70.6-0.5-0.2-0.6
Mean time between licks in bursts0.10.31.00.8-0.3-0.2-0.7-0.60.6-0.5-0.6-0.70.00.50.2-1.00.5
Mean num. licks in bursts2.05.38.9-1.82.71.91.92.3-2.21.91.91.8-2.8-3.03.0-1.82.7
Cd content in liver0.50.62.30.7-0.5-0.7-0.6-0.70.8-0.8-0.7-0.70.10.10.2-1.51.0
Co content in liver0.60.81.60.7-1.0-1.3-0.5-1.21.2-0.9-1.1-1.20.70.3-0.6-0.30.0
Cu content in liver0.20.21.10.4-0.0-0.3-0.4-0.30.3-0.3-0.3-0.3-0.1-0.00.4-1.10.8
Fe content in liver1.11.41.8-1.31.31.31.21.3-1.31.31.31.3-0.7-1.10.41.3-0.6
K content in liver2.52.44.71.3-1.9-1.2-1.7-1.51.4-1.6-1.3-0.92.22.0-2.10.9-1.3
Mg content in liver0.30.40.90.6-0.9-0.4-0.7-0.70.7-0.5-0.7-0.70.80.5-0.70.3-0.1
Mn content in liver0.40.41.00.5-0.5-0.5-0.6-0.60.6-0.9-0.5-0.21.00.7-0.90.3-0.7
Na content in liver2.12.43.41.8-1.8-1.7-1.7-1.81.8-1.5-1.7-1.81.61.3-1.4-0.0-0.7
Rb content in liver1.01.12.01.1-1.2-1.1-1.2-1.21.1-1.4-1.2-0.90.90.9-0.6-1.20.6
Se content in liver1.51.72.71.2-1.5-1.2-1.6-1.41.3-1.5-1.3-1.11.61.5-1.50.1-0.6
Sr content in liver4.13.55.42.0-2.3-2.0-2.1-2.12.1-1.7-2.2-2.31.72.0-1.7-0.1-0.2
Zn content in liver0.60.81.90.5-1.0-0.6-0.9-0.70.7-1.2-0.7-0.21.41.1-1.30.2-0.5
Bone: minimum diameter0.00.00.2-0.3-0.00.10.10.2-0.2-0.00.30.50.20.2-0.10.20.2
Time in familiar zone, hab. session 10.00.00.30.00.20.10.20.1-0.10.20.10.0-0.0-0.5-0.00.3-0.2
Time in novel zone, hab. session 10.10.20.80.1-0.2-0.3-0.4-0.10.1-0.2-0.2-0.2-0.10.50.3-0.80.9
Total zone transitions, hab. session 10.00.00.10.20.3-0.1-0.20.0-0.0-0.2-0.00.10.2-0.1-0.1-0.1-0.2
Total locomotion distance, hab. session 10.50.72.30.6-0.6-0.5-0.6-0.50.5-0.5-0.4-0.31.10.5-1.31.3-1.5
Locomotion velocity, hab. session 10.30.41.90.4-0.2-0.2-0.2-0.20.2-0.1-0.1-0.10.70.2-0.91.3-1.4
Time in familiar zone, hab. session 21.31.42.5-1.31.21.31.51.3-1.31.21.31.3-1.1-1.60.90.40.7
Time in novel zone, hab. session 21.41.52.51.4-1.0-1.4-1.6-1.31.3-1.3-1.4-1.40.81.4-0.4-1.30.2
Total zone transitions, hab. session 21.11.42.51.3-1.0-1.2-1.4-1.11.1-1.5-1.1-0.61.61.3-1.40.1-1.0
Total locomotion distance, hab. session 21.31.62.51.5-1.2-1.4-1.4-1.31.3-1.6-1.3-0.91.61.0-1.50.1-1.0
Locomotion velocity, hab. session 21.82.44.01.7-1.6-1.6-1.6-1.61.6-1.8-1.5-1.02.01.4-2.00.5-1.4
Novel to familiar place preference ratio0.10.10.70.50.1-0.2-0.4-0.30.3-0.3-0.3-0.4-0.2-0.10.2-0.80.2
Novelty place preference0.10.21.00.50.2-0.2-0.4-0.20.3-0.3-0.3-0.3-0.3-0.10.4-1.00.4
Time in novel zone, NPP test0.20.21.40.40.2-0.2-0.4-0.20.2-0.2-0.3-0.3-0.4-0.10.5-1.20.6
Total zone transitions, NPP test0.30.42.4-0.3-0.10.20.10.3-0.30.10.30.60.70.4-0.91.5-1.2
Total locomotion distance, NPP test0.60.93.40.3-0.8-0.2-0.4-0.30.3-0.4-0.10.11.30.9-1.51.8-1.8
Locomotion velocity, NPP test0.81.13.60.5-1.0-0.4-0.6-0.50.5-0.6-0.3-0.01.50.9-1.71.8-1.9
Intraocular pressure0.20.30.60.6-0.4-0.8-0.5-0.60.6-0.7-0.7-0.70.30.5-0.3-0.5-0.0
Delta distance traveled before/after self-admin0.50.61.6-0.80.70.70.60.7-0.70.50.60.8-0.1-0.6-0.41.3-1.2
Delta ambulatory time before/after self-admin0.30.51.6-0.80.60.70.60.7-0.70.60.60.7-0.2-0.5-0.31.3-1.0
Parametrial fat weight1.43.47.72.2-1.5-2.4-2.0-1.91.9-2.3-2.0-1.71.10.7-0.3-2.81.2
Pavlov. Cond. lever latency0.10.20.90.2-0.1-0.2-0.2-0.30.3-0.0-0.3-0.5-0.3-0.40.4-0.80.9
Pavlov. Cond. magazine entry latency1.21.52.2-1.31.41.41.41.5-1.41.41.51.4-1.0-1.00.90.8-0.4
Pavlov. Cond. change in total contacts1.31.42.41.5-1.0-1.5-1.3-1.31.4-1.5-1.4-1.21.11.0-0.9-0.8-0.4
Pavlov. Cond. index score0.70.91.5-1.10.91.11.11.1-1.10.91.11.2-0.5-0.50.31.0-0.8
Pavlov. Cond. latency score0.60.81.4-1.00.81.01.01.0-1.10.81.01.2-0.3-0.30.21.0-0.8
Pavlov. Cond. lever contacts0.20.20.7-0.40.30.40.50.5-0.60.20.50.70.20.0-0.30.7-0.8
Pavlov. Cond. magazine entry number1.11.42.21.2-1.5-1.2-1.4-1.41.3-1.2-1.3-1.31.21.1-1.1-0.2-0.1
Pavlov. Cond. intertrial magazine entries1.72.17.40.8-1.3-0.9-0.9-1.01.0-1.1-0.8-0.41.91.5-2.11.8-2.7
Pavlov. Cond. lever-magazine prob. diff.0.91.11.9-1.31.01.21.31.2-1.31.01.31.4-0.5-0.60.31.1-0.8
Pavlov. Cond. response bias0.20.30.5-0.50.60.50.60.6-0.60.40.60.7-0.1-0.20.10.6-0.6
Pavlov. Cond. lever latency3.54.97.52.0-2.7-2.2-2.5-2.32.2-2.4-2.2-1.82.72.7-2.50.3-1.2
Pavlov. Cond. magazine entry latency0.10.10.6-0.20.40.40.50.2-0.20.50.30.1-0.3-0.80.20.3-0.1
Pavlov. Cond. change in total contacts0.10.30.6-0.50.70.60.70.6-0.60.60.60.6-0.7-0.70.60.00.2
Pavlov. Cond. index score1.01.62.8-1.11.51.31.51.3-1.31.41.31.0-1.4-1.71.30.20.5
Pavlov. Cond. latency score1.01.62.5-1.21.51.31.51.3-1.31.41.41.1-1.3-1.61.20.40.3
Pavlov. Cond. lever contacts3.65.37.8-2.22.82.32.62.4-2.42.52.42.0-2.7-2.82.5-0.01.0
Pavlov. Cond. magazine entry number0.50.71.80.3-0.9-0.5-0.6-0.50.5-0.7-0.4-0.21.11.3-1.30.9-1.2
Pavlov. Cond. intertrial magazine entries0.00.10.10.2-0.2-0.2-0.4-0.30.3-0.4-0.3-0.20.30.2-0.3-0.10.1
Pavlov. Cond. lever-magazine prob. diff.1.21.83.2-1.21.61.41.61.4-1.41.61.41.1-1.5-1.81.40.20.6
Pavlov. Cond. response bias2.33.25.8-1.52.31.71.91.8-1.71.91.71.3-2.2-2.42.1-0.41.0
Time in closed arm before self-admin0.10.30.40.5-0.3-0.6-0.6-0.60.6-0.6-0.5-0.40.50.4-0.5-0.1-0.6
Time in closed arm after self-admin1.72.03.0-1.71.61.41.71.6-1.51.21.51.7-0.8-1.30.31.4-1.4
Time in open arm before self-admin0.70.91.8-0.90.91.00.91.1-1.11.10.90.8-0.7-0.30.11.4-1.2
Time in open arm after self-admin0.50.51.90.8-0.5-0.7-0.7-0.60.6-0.8-0.7-0.60.40.10.2-1.41.0
Bone: periosteal estimation0.40.91.21.1-1.1-1.1-1.0-1.11.1-1.0-1.0-1.01.10.9-1.00.1-0.5
Bone: periosteal perimeter1.22.43.71.5-1.8-1.5-1.5-1.61.6-1.6-1.6-1.41.91.5-1.90.6-0.9
Bone: post-yield work0.00.10.50.1-0.0-0.00.0-0.10.10.0-0.1-0.30.2-0.1-0.30.5-0.7
Progressive ratio test 1 active lever presses0.40.71.80.8-0.6-0.7-1.0-0.60.6-1.0-0.7-0.30.91.0-1.00.1-1.3
Progressive ratio test 1 breakpoint0.40.72.00.8-0.6-0.7-1.0-0.70.6-1.1-0.7-0.30.90.9-1.00.1-1.4
Progressive ratio test 1 inactive lever presses2.15.59.62.5-2.5-2.5-2.8-2.42.4-3.1-2.3-1.52.62.6-2.3-0.8-1.3
Progressive ratio test 2 active lever presses0.40.51.01.0-0.7-0.6-0.9-0.70.7-0.6-0.8-1.00.50.7-0.60.0-0.6
Progressive ratio test 2 breakpoint0.30.40.90.9-0.7-0.6-0.9-0.70.7-0.5-0.8-0.90.50.6-0.50.0-0.5
Progressive ratio test 2 inactive lever presses0.51.52.71.4-1.3-1.4-1.4-1.31.3-1.7-1.3-0.91.20.7-1.3-0.4-0.7
Incentive Sensitization - Responses0.10.31.10.7-0.8-0.5-0.3-0.60.7-0.1-0.6-1.10.30.1-0.40.30.1
Incentive Sensitization - Breakpoint0.10.21.10.6-0.8-0.4-0.2-0.60.60.1-0.6-1.00.10.0-0.20.30.3
Sum of active levers in priming session hrs 5-60.90.92.40.8-1.4-0.7-1.1-0.90.8-0.7-0.9-0.80.91.5-1.10.4-0.3
Progressive ratio0.00.10.6-0.3-0.00.30.00.3-0.3-0.00.40.80.10.2-0.20.30.0
Food seeking constrained by brief footshock3.34.16.62.0-2.4-2.0-2.1-2.01.9-2.2-1.8-1.32.42.2-2.60.7-1.9
Seeking ratio, punishment vs. effort0.81.83.11.3-1.2-1.4-1.1-1.41.4-1.4-1.3-1.21.61.2-1.50.4-1.8
Retroperitoneal fat weight0.52.03.71.7-1.5-1.9-1.5-1.61.6-1.7-1.6-1.51.10.8-0.7-1.30.4
Reaction time number correct0.10.21.10.10.40.20.20.10.00.1-0.1-0.2-0.5-0.80.6-0.91.0
Reaction time mean minus median0.53.25.2-1.62.01.91.91.8-1.72.11.61.1-2.3-2.02.1-0.21.7
Reaction time mean minus median AUC0.42.44.0-1.41.81.81.61.6-1.62.01.50.9-2.0-1.61.80.11.0
Reaction time num false alarms0.81.32.21.0-1.5-1.1-1.2-1.21.2-1.0-1.2-1.21.41.2-1.30.5-0.8
Reaction time num false alarms AUC0.71.62.80.9-1.7-1.1-1.2-1.21.1-0.9-1.1-1.21.51.4-1.71.1-1.2
Reaction time trials correct on left0.10.21.10.10.40.20.20.10.00.1-0.1-0.2-0.5-0.80.6-0.91.0
Reaction time trials on left0.10.31.10.00.50.20.30.1-0.00.1-0.0-0.2-0.6-0.90.6-0.81.1
Reaction time mean0.40.91.6-1.20.81.31.11.0-1.01.11.00.9-1.0-0.70.70.40.6
Reaction time mean AUC0.51.32.4-1.51.01.51.31.2-1.31.31.21.2-1.1-0.80.70.70.4
Median of all reaction times0.30.41.0-1.00.40.90.70.7-0.70.60.70.9-0.5-0.30.20.40.2
Reaction time omissions0.71.11.9-1.31.01.31.31.1-1.11.41.10.8-1.2-0.91.00.40.6
Reaction time false alarm rate1.41.93.60.8-1.8-1.1-1.2-1.21.1-0.9-1.1-1.11.71.7-1.91.5-1.6
Reaction time premature initiation rate1.52.44.6-1.81.61.71.61.8-1.91.51.92.1-1.0-0.80.71.2-0.7
Reaction time premature initiations0.51.62.5-1.41.61.41.41.5-1.51.21.51.6-1.1-0.91.00.40.0
Std. dev. reaction times0.62.03.4-1.51.41.71.51.4-1.51.81.40.9-1.8-1.31.50.21.3
Reaction time trials completed0.10.31.10.00.50.20.30.1-0.00.1-0.0-0.2-0.6-0.90.6-0.81.1
Reaction time trials AUC0.10.20.90.10.30.10.1-0.00.1-0.0-0.2-0.3-0.4-0.70.5-0.81.0
Run reversals in cocaine runway, females0.60.63.4-0.30.30.50.50.4-0.40.70.40.20.0-0.2-0.61.8-1.8
Run reversals in cocaine runway, males0.10.10.60.4-0.1-0.4-0.3-0.30.4-0.6-0.3-0.20.20.20.0-0.80.3
Latency to leave start box in cocaine runway0.50.71.40.6-1.1-0.8-0.8-0.80.8-0.6-0.8-0.81.01.2-1.00.5-0.5
Latency to leave start box in cocaine runway, F1.82.24.21.3-2.0-1.4-1.5-1.51.4-1.0-1.4-1.61.62.0-1.60.9-1.0
Latency to leave start box in cocaine runway, M0.30.30.6-0.70.70.40.70.5-0.50.10.50.8-0.5-0.80.4-0.30.4
Std. dev. time between licks in bursts0.00.00.20.40.10.1-0.0-0.20.20.0-0.1-0.3-0.1-0.10.10.0-0.4
Total sessions with >9 infusions0.91.12.2-1.21.21.20.91.3-1.30.91.31.5-0.9-0.50.60.4-0.4
Short access day 1 total inactive lever presses1.53.05.52.0-1.6-1.8-2.2-1.81.8-2.3-1.8-1.31.71.9-1.2-1.4-0.2
Short access day 10 total inactive lever presses0.00.20.80.40.0-0.5-0.4-0.20.3-0.9-0.20.30.40.1-0.2-0.7-0.3
Short access day 1 total infusions0.40.82.5-1.11.11.00.81.2-1.10.51.11.6-0.7-0.60.40.2-0.3
Short access day 10 total infusions0.30.41.2-0.60.60.80.50.8-0.80.50.70.7-0.4-0.0-0.10.9-1.1
Short access total infusions0.00.10.2-0.10.10.2-0.10.3-0.3-0.10.20.5-0.10.40.0-0.1-0.2
Short access day 1 locomotion0.71.12.7-1.11.11.20.81.3-1.30.51.11.6-0.4-0.5-0.21.2-1.3
Short access day 10 total locomotion0.41.75.0-1.31.61.21.31.5-1.40.41.42.2-0.6-1.2-0.10.9-1.4
Short access total locomotion1.11.74.4-1.41.71.51.21.6-1.60.81.62.1-0.9-1.00.50.5-0.7
One hour access (0.3 mA shock)0.70.91.61.3-0.9-0.8-1.3-0.90.9-1.2-1.0-0.70.90.7-0.9-0.3-0.8
Compulsive drug intake1.11.73.0-1.41.31.61.41.5-1.41.71.31.0-1.1-1.30.71.4-0.3
One hour access (shock baseline)0.40.91.71.2-1.0-1.0-1.3-1.01.0-1.3-1.0-0.70.80.8-0.7-0.8-0.1
Social response proportion0.91.22.11.2-1.2-1.2-1.4-1.11.1-1.5-1.1-0.71.21.1-0.8-0.80.0
Social responses1.62.13.41.6-1.4-1.6-1.5-1.61.7-1.8-1.6-1.41.10.8-0.5-1.80.8
Social time0.20.31.20.2-0.5-0.5-0.4-0.50.5-0.6-0.5-0.30.20.30.1-1.11.0
Soleus weight1.02.96.01.3-2.2-1.4-1.7-1.61.6-1.7-1.5-1.22.22.5-2.20.8-1.1
Bone: stiffness0.10.20.4-0.30.50.30.50.4-0.30.30.40.4-0.4-0.60.4-0.1-0.2
Tibialis anterior weight0.93.15.02.1-2.1-2.2-1.9-2.02.0-1.7-2.0-2.21.31.4-1.1-0.90.1
Time to tail flick, vehicle, before self-admin0.30.31.10.1-0.5-0.3-0.4-0.30.2-0.7-0.20.40.70.6-1.10.6-0.9
Time to tail flick, vehicle, after self-admin0.10.10.6-0.0-0.2-0.1-0.0-0.20.1-0.2-0.10.10.50.1-0.60.7-0.7
Time to tail flick, test, before self-admin0.30.31.0-0.50.60.60.20.5-0.50.80.50.2-0.70.11.0-0.40.8
Time to tail flick, test, after self-admin2.93.15.21.8-1.5-1.8-2.0-1.71.8-2.3-1.8-1.32.01.8-1.9-0.2-1.7
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.40.30.40.50.4-0.40.60.40.2-0.1-0.4-0.00.9-0.5
Delta time to tail flick, test, before/after SA1.41.73.71.5-1.2-1.5-1.3-1.41.4-1.9-1.4-0.91.50.5-1.5-0.4-1.0
Tibia length0.31.04.4-0.2-0.8-0.1-0.1-0.10.10.10.20.31.01.2-1.22.1-2.1
Ambulatory time before self-admin0.10.40.70.8-0.6-0.6-0.6-0.70.7-0.6-0.7-0.80.50.6-0.3-0.3-0.2
Ambulatory time after self-admin0.10.21.10.10.0-0.0-0.2-0.00.0-0.2-0.10.10.30.2-0.60.6-1.1
Bone: tissue strength0.70.72.0-0.20.70.30.50.4-0.40.60.30.0-1.2-1.21.4-1.41.3
Total heroin consumption0.10.10.7-0.1-0.20.1-0.40.1-0.1-0.0-0.00.1-0.20.50.1-0.40.8
Bone: trabecular number0.00.00.0-0.20.00.00.10.1-0.10.20.10.1-0.10.10.10.10.0
Bone: trabecular spacing0.71.01.51.2-1.2-1.0-1.2-1.21.1-1.0-1.1-1.10.91.2-0.8-0.1-0.5
Bone: trabecular thickness0.50.72.4-0.80.50.80.80.8-0.80.70.80.9-0.1-0.6-0.31.5-1.0
Bone: trabecular tissue density0.61.02.7-0.71.40.91.01.0-0.91.00.80.6-1.3-1.61.2-0.30.8
Water consumed over 24 hours0.40.83.11.2-0.1-0.9-0.9-0.60.7-0.6-0.8-1.0-0.2-0.10.6-1.81.3
Number of responses in last shaping day0.10.20.8-0.20.30.20.10.3-0.3-0.10.30.50.1-0.5-0.40.5-0.9