Hub : Genes

Nubpl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr6_75506753_75510544 0.06 0.04 6.6e-06 0.05 0.05 0.05 0.05 6.2e-06 2.0e-06 5.4e-06 7.4e-06
2 pVTA intron excision ratio chr6_75510626_75516353 0.06 0.05 2.4e-03 0.03 0.03 0.02 0.03 2.9e-03 1.2e-03 5.5e-03 3.0e-03
3 NAcc intron excision ratio chr6_75506753_75510544 0.03 0.02 1.5e-04 0.03 0.02 0.02 0.02 7.3e-05 1.7e-04 1.8e-04 4.0e-04
4 Brain intron excision ratio chr6_75506753_75510544 0.14 0.13 7.0e-04 0.04 0.02 0.02 0.03 7.0e-05 3.3e-03 3.9e-03 5.7e-04
5 Adipose intron excision ratio chr6_75506753_75510544 0.03 0.02 1.4e-03 0.01 0.02 0.02 0.02 1.1e-02 1.1e-03 1.5e-03 3.6e-03
6 Adipose gene expression Nubpl 0.03 0.02 3.6e-03 0.02 0.02 0.01 0.02 2.6e-03 2.1e-03 3.4e-02 1.1e-03
7 Brain intron excision ratio chr6_75297419_75344810 0.1 0.06 3.4e-07 0.07 0.08 0.08 0.09 2.2e-07 1.3e-07 1.1e-07 1.7e-08
8 OFC alternative TSS XM_008764655.4 0.16 0.12 7.6e-03 0 0.07 0 0.02 2.8e-01 9.4e-03 2.6e-01 1.0e-01
9 IL gene expression Nubpl 0.35 0.15 1.3e-06 0.18 0.23 0.15 0.18 3.5e-05 2.4e-06 1.9e-04 4.0e-05
10 NAcc intron excision ratio chr6_75297419_75344810 0.08 0.05 2.4e-11 0.06 0.07 0.08 0.08 4.6e-10 6.3e-11 3.1e-12 2.9e-12
11 BLA gene expression Nubpl 0.18 0.11 1.0e-07 0.14 0.13 0.13 0.14 5.9e-08 1.4e-07 2.9e-07 1.2e-07
12 Brain gene expression Nubpl 0.1 0.06 1.7e-08 0.09 0.09 0.08 0.09 1.3e-08 5.0e-09 6.2e-08 1.1e-08
13 OFC alternative TSS XM_008764655.4 0.16 0.11 7.0e-03 0.02 0.07 0.01 0.03 1.2e-01 1.0e-02 1.5e-01 6.2e-02
14 Liver intron excision ratio chr6_75510626_75516353 0.03 0.02 1.9e-03 0.02 0.02 0.01 0.02 1.1e-03 1.1e-03 1.1e-02 2.0e-03
15 PL intron excision ratio chr6_75297419_75344810 0.13 0.08 6.0e-13 0.08 0.1 0.09 0.09 2.0e-09 1.3e-10 2.9e-10 6.4e-10
16 OFC gene expression Nubpl 0.44 0.27 3.6e-05 0.25 0.14 0.19 0.21 1.5e-06 3.2e-04 3.4e-05 8.2e-06
17 Liver alternative polyA XM_008764655.4 0.03 0.02 4.6e-03 0.01 0 0.01 0.01 6.8e-02 9.2e-02 5.5e-02 4.9e-02
18 BLA alternative TSS XM_008764655.4 0.06 0.04 3.2e-03 0.04 0.04 0.03 0.04 2.7e-03 4.1e-03 1.7e-02 4.7e-03
19 NAcc intron excision ratio chr6_75297419_75329509 0.03 0.02 3.5e-04 0.03 0.02 0.02 0.03 1.5e-05 2.6e-04 2.2e-04 8.5e-05
20 NAcc gene expression Nubpl 0.06 0.04 2.5e-09 0.08 0.06 0.06 0.07 8.4e-12 6.8e-10 3.6e-09 3.8e-11
21 pVTA intron excision ratio chr6_75297419_75344810 0.04 0.03 4.7e-03 0.04 0.03 0.02 0.03 7.8e-04 2.5e-03 6.3e-03 2.9e-03
22 PL gene expression Nubpl 0.19 0.11 5.6e-17 0.14 0.15 0.16 0.15 1.4e-15 4.3e-16 1.5e-17 4.7e-16
23 pVTA gene expression Nubpl 0.04 0.03 4.9e-03 0.02 0.02 0.03 0.02 8.1e-03 6.6e-03 1.9e-03 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.32.25.62.3-2.42.22.32.0-2.31.8-0.41.51.00.91.30.1-1.01.10.61.20.8-1.01.41.40.70.6
Area under the delay curve1.31.53.60.7-0.4-0.10.2-0.70.6-0.6-1.9-1.2-1.3-1.8-1.4-1.81.7-1.5-0.6-1.3-1.51.4-1.4-1.4-1.0-0.1
BMI with tail1.13.65.61.2-1.51.81.72.2-2.02.41.42.32.12.12.21.7-1.92.22.12.02.0-2.01.71.71.71.5
BMI without tail2.57.611.02.0-2.32.72.63.3-3.23.31.83.32.93.03.22.3-2.63.12.82.92.7-2.52.82.82.51.8
Body weight1.25.415.93.8-3.94.03.63.3-3.12.6-0.42.51.51.62.30.4-1.42.01.41.91.5-1.41.31.31.11.2
Weight adjusted by age0.20.41.5-1.21.2-0.8-1.1-0.71.1-0.50.7-0.30.10.2-0.10.5-0.3-0.10.0-0.10.2-0.3-0.7-0.70.30.0
Bone surface0.81.44.22.0-1.91.31.60.6-0.5-0.7-2.0-0.2-1.3-1.1-0.5-1.61.0-0.7-1.3-0.7-1.00.9-1.0-1.0-1.1-0.3
Bone volume0.71.25.72.4-2.31.82.11.2-1.30.3-1.50.5-0.5-0.40.2-1.10.3-0.0-0.6-0.0-0.40.3-0.1-0.1-0.50.0
Breakpoint value in progressive ratio session0.81.04.62.1-2.12.11.81.3-1.20.7-1.10.6-0.10.10.5-0.7-0.00.30.10.2-0.20.30.00.0-0.10.4
Number of licking bursts0.10.23.0-0.30.2-0.30.0-0.1-0.20.40.1-0.10.20.1-0.00.1-0.2-0.00.1-0.3-0.20.10.30.30.81.7
Context. condit. distance diff. score1.62.04.00.5-0.60.31.41.3-1.71.50.91.51.71.11.31.1-1.61.30.91.61.8-1.91.51.52.01.4
Locomotion velocity, session 10.20.20.40.1-0.10.0-0.1-0.30.2-0.4-0.5-0.5-0.5-0.5-0.4-0.60.5-0.5-0.4-0.6-0.70.5-0.4-0.4-0.40.4
Locomotion distance, session 10.50.63.0-1.71.7-1.6-1.4-1.10.9-0.60.8-0.6-0.1-0.1-0.50.40.0-0.3-0.2-0.4-0.10.10.20.20.30.3
Locomotion velocity, session 22.12.54.0-1.41.6-2.0-1.5-2.01.7-1.9-0.8-1.9-1.7-1.5-1.8-1.21.7-1.8-1.5-1.9-1.61.6-1.5-1.5-0.70.5
Locomotion distance, session 21.62.26.3-2.42.5-2.2-2.5-2.12.1-1.60.3-1.6-1.1-0.7-1.4-0.20.9-1.2-0.8-1.4-1.21.2-0.8-0.8-0.8-0.5
Locomotion velocity, session 31.01.13.7-1.51.5-1.9-1.1-1.41.1-1.3-0.2-1.2-0.8-0.9-1.2-0.51.1-1.1-1.1-0.9-0.50.6-0.7-0.70.20.7
Locomotion distance, session 30.80.94.3-0.70.5-0.70.20.2-0.50.61.10.61.10.80.61.0-0.90.70.70.81.1-1.10.70.71.92.1
Stereotopy head waving bouts, day 31.72.03.5-1.41.6-1.9-1.5-1.81.6-1.8-0.6-1.6-1.4-1.5-1.6-0.91.4-1.5-1.5-1.3-1.11.3-1.0-1.0-1.0-0.9
Stereotopy head waving duration, day 31.92.23.8-1.31.5-1.6-1.5-1.81.7-2.0-0.7-1.7-1.7-1.5-1.6-1.01.5-1.6-1.5-1.5-1.51.6-1.2-1.2-1.4-1.2
Locomotion velocity, session 73.64.07.7-1.30.9-0.6-0.20.9-1.01.92.81.72.62.21.82.7-2.52.02.12.02.5-2.52.22.22.51.7
Locomotion distance, session 73.74.78.6-0.60.20.30.31.4-1.22.52.62.02.82.62.22.6-2.62.32.62.22.4-2.61.81.82.92.9
Stereotopy head waving bouts, day 70.60.71.6-0.00.2-0.4-0.3-0.70.4-0.9-0.9-0.8-1.0-1.1-0.9-0.91.2-0.9-1.1-0.8-0.80.9-0.2-0.2-1.1-1.3
Stereotopy head waving duration, day 71.61.94.2-0.50.8-1.1-0.8-1.30.9-1.8-1.1-1.4-1.8-1.7-1.5-1.31.7-1.5-1.7-1.4-1.51.6-0.5-0.5-1.6-2.0
Locomotion velocity, session 80.30.31.0-0.40.5-0.5-0.5-0.60.6-0.8-0.4-0.6-0.5-0.5-0.6-0.40.6-0.6-0.9-0.5-0.30.2-0.5-0.5-0.5-1.0
Locomotion distance, session 80.20.31.0-0.60.5-0.80.10.0-0.30.20.60.30.50.30.20.6-0.80.30.00.40.7-0.80.50.51.00.7
Degree of sensitization distance0.30.30.90.5-0.50.70.30.6-0.60.90.30.60.70.50.60.4-0.60.60.70.50.4-0.60.60.60.40.4
Degree of sensitization stereotypy0.40.41.80.8-0.70.50.40.0-0.2-0.3-1.0-0.3-0.7-0.7-0.4-0.80.8-0.5-0.7-0.4-0.60.7-0.1-0.1-1.1-1.4
Conditioned locomotion1.11.32.9-1.11.2-1.7-1.0-1.41.0-1.3-0.6-1.3-1.1-1.3-1.4-0.91.4-1.3-1.3-1.3-1.11.1-0.7-0.7-0.40.2
Cocaine response after cond. corrected0.30.31.1-0.20.1-0.10.30.4-0.3-0.00.80.60.50.60.60.8-0.90.70.60.81.0-1.00.50.50.5-0.0
Cocaine response after cond. not corrected1.01.22.10.1-0.30.60.51.0-0.80.71.31.31.11.41.31.4-1.41.41.41.41.4-1.41.01.00.80.1
Cocaine response before conditioning0.60.71.80.1-0.30.9-0.00.7-0.41.21.00.91.01.31.11.1-0.71.11.30.90.7-0.60.90.90.40.1
Saline control response0.50.72.21.4-1.51.41.41.3-1.10.9-0.20.90.40.60.80.1-0.50.70.60.60.3-0.40.30.30.40.5
Bone: connectivity density2.84.410.73.2-3.33.03.23.0-3.12.4-0.32.31.51.42.00.4-1.41.81.11.91.5-1.51.81.81.20.9
Bone: cortical apparent density0.81.12.7-0.70.5-0.0-0.50.50.01.11.60.91.51.51.11.6-1.61.21.51.11.3-1.50.50.50.7-0.2
Bone: cortical area1.11.75.42.2-2.01.21.80.5-0.7-0.6-2.3-0.3-1.3-1.5-0.7-2.01.4-0.9-1.5-0.7-1.01.2-1.0-1.0-1.2-0.3
Bone: cortical porosity1.11.12.40.2-0.0-0.3-0.1-0.70.5-1.4-1.4-1.0-1.4-1.4-1.2-1.41.5-1.2-1.5-1.0-1.01.1-0.8-0.8-1.2-1.2
Bone: cortical porosity1.01.12.20.3-0.0-0.3-0.1-0.70.4-1.3-1.4-1.0-1.3-1.4-1.2-1.41.4-1.2-1.5-1.0-1.01.1-0.7-0.7-1.3-1.3
Bone: cortical thickness0.20.31.41.2-1.10.91.10.9-0.70.5-0.40.60.20.10.4-0.2-0.10.30.10.50.5-0.3-0.2-0.20.10.3
Bone: cortical thickness0.20.20.5-0.50.5-0.3-0.30.0-0.10.10.60.20.50.40.30.6-0.30.30.10.60.7-0.60.60.60.60.0
Bone: cortical tissue density0.81.12.6-0.70.6-0.1-0.50.40.11.11.60.91.41.41.11.5-1.61.21.41.01.2-1.50.50.50.7-0.1
Condit. Reinf. active minus inactive responses0.91.03.61.9-1.81.51.60.7-0.50.1-1.6-0.0-0.7-0.5-0.2-1.20.6-0.4-0.4-0.5-0.90.8-0.9-0.9-0.41.1
Condit. Reinf. active-inactive response ratio0.20.21.20.7-0.70.60.70.3-0.60.3-0.50.1-0.2-0.10.0-0.40.0-0.10.1-0.2-0.50.40.20.20.31.1
Condit. Reinf. active responses1.31.74.42.1-1.91.51.60.4-0.2-0.6-2.1-0.4-1.5-1.0-0.6-1.81.2-0.8-1.0-0.9-1.31.4-1.6-1.6-1.00.4
Condit. Reinf. inactive responses0.50.71.80.8-0.70.50.4-0.10.3-0.8-1.2-0.5-1.0-0.7-0.6-1.10.9-0.6-0.8-0.5-0.70.8-1.3-1.3-1.0-0.4
Incentive salience index mean1.21.54.51.9-1.81.31.40.3-0.3-0.4-2.1-0.5-1.3-1.1-0.7-1.81.3-1.0-1.0-0.9-1.41.3-1.2-1.2-0.80.8
Condit. Reinf. lever presses0.30.51.20.6-0.50.30.3-0.30.1-0.4-1.1-0.6-0.9-0.7-0.7-1.00.9-0.8-0.7-0.7-1.00.9-0.6-0.6-0.60.3
Condit. Reinf. active minus inactive responses0.10.10.3-0.50.5-0.4-0.4-0.30.40.00.2-0.20.20.1-0.10.10.1-0.10.00.10.1-0.1-0.3-0.30.40.6
Condit. Reinf. active-inactive response ratio0.20.20.6-0.80.8-0.7-0.8-0.70.7-0.30.0-0.6-0.2-0.4-0.5-0.20.3-0.5-0.5-0.3-0.30.4-0.3-0.3-0.1-0.2
Condit. Reinf. active responses0.10.20.7-0.70.6-0.5-0.6-0.50.60.10.2-0.30.30.0-0.20.10.2-0.20.00.00.1-0.1-0.3-0.30.40.9
Condit. Reinf. inactive responses0.30.31.1-0.1-0.00.30.00.3-0.30.80.60.40.90.70.50.6-0.40.50.80.50.6-0.70.50.50.71.0
Condit. Reinf. lever presses0.20.31.00.9-0.91.00.50.30.00.3-0.8-0.1-0.1-0.2-0.1-0.60.4-0.2-0.1-0.3-0.40.3-0.7-0.7-0.20.4
Condit. Reinf. lever reinforcers received0.10.20.50.3-0.20.20.1-0.20.30.0-0.7-0.4-0.2-0.5-0.5-0.70.6-0.5-0.5-0.3-0.40.2-0.7-0.70.00.7
Conditioned reinforcement - actives0.61.13.51.7-1.51.01.10.3-0.2-0.3-1.9-0.4-0.9-1.0-0.7-1.61.0-0.8-0.8-0.7-1.01.1-1.0-1.0-1.1-0.4
Conditioned reinforcement - inactives0.81.14.22.1-2.02.01.81.4-1.31.2-0.80.90.60.40.7-0.4-0.40.50.60.70.4-0.50.30.30.50.8
Conditioned locomotion0.00.00.10.3-0.30.30.30.1-0.2-0.0-0.20.0-0.00.0-0.0-0.2-0.0-0.0-0.30.10.0-0.0-0.0-0.00.20.1
Patch foraging indifference point 0 sec1.01.85.12.0-1.81.41.20.3-0.2-0.9-2.3-0.6-1.6-1.2-0.8-2.01.2-1.0-1.6-1.0-1.41.2-1.4-1.4-1.7-0.4
Patch foraging indifference point AUC1.31.94.70.8-0.5-0.20.4-0.70.4-1.2-2.2-1.3-1.6-2.1-1.5-2.11.8-1.6-1.8-1.2-1.31.2-1.3-1.3-1.4-1.3
Delay disc. indifference point, 0s delay0.60.61.50.5-0.4-0.20.4-0.30.1-0.5-1.2-0.7-1.0-1.1-0.8-1.21.0-0.9-1.1-0.7-0.91.2-0.8-0.8-0.40.1
Delay disc. indifference point, 16s delay1.71.93.70.3-0.1-0.4-0.2-1.01.1-1.1-1.8-1.5-1.5-1.9-1.6-1.91.7-1.7-1.1-1.5-1.61.4-1.8-1.8-1.1-0.4
Delay disc. indifference point, 2s delay0.20.30.80.7-0.60.20.50.0-0.2-0.3-0.9-0.3-0.6-0.7-0.4-0.80.7-0.5-0.1-0.4-0.60.8-0.3-0.3-0.7-0.0
Delay disc. indifference point, 24s delay2.32.66.00.9-0.60.10.0-0.91.0-1.1-2.4-1.6-1.8-2.1-1.8-2.42.1-1.9-1.2-1.9-2.11.8-1.9-1.9-1.5-0.4
Delay disc. indifference point, 4s delay0.30.30.8-0.50.5-0.9-0.3-0.60.6-0.6-0.3-0.6-0.6-0.8-0.7-0.40.8-0.6-0.4-0.4-0.50.5-0.8-0.8-0.2-0.0
Delay disc. indifference point, 8s delay0.20.30.80.7-0.60.50.50.1-0.20.6-0.9-0.3-0.1-0.7-0.4-0.80.7-0.40.6-0.3-0.50.4-0.2-0.20.00.6
Indifference point function ln k0.20.41.1-0.1-0.10.40.10.5-0.20.60.90.70.61.00.80.9-1.00.80.70.60.5-0.60.30.30.60.6
Indifference point function log k0.20.41.1-0.1-0.10.40.10.5-0.20.60.90.70.61.00.80.9-1.00.80.70.60.5-0.60.30.30.60.6
Patch foraging total patch changes 0 sec1.22.36.42.1-1.91.41.30.2-0.1-1.0-2.5-0.7-1.8-1.5-1.0-2.21.4-1.2-1.9-1.2-1.61.4-1.6-1.6-1.8-0.5
Patch foraging total patch changes 12 sec1.51.95.71.9-1.71.21.20.1-0.2-0.8-2.4-0.7-1.5-1.5-1.0-2.11.5-1.2-1.5-1.0-1.51.5-1.1-1.1-1.7-0.8
Patch foraging total patch changes 18 sec0.40.61.50.9-0.80.70.3-0.10.2-0.5-1.2-0.5-0.8-0.7-0.6-1.10.9-0.7-0.8-0.5-0.80.7-0.8-0.8-1.2-0.7
Patch foraging total patch changes 24 sec0.61.12.30.8-0.60.60.0-0.40.6-0.9-1.5-0.9-1.2-1.1-0.9-1.41.2-1.0-1.2-0.9-1.21.1-1.3-1.3-1.5-1.1
Patch foraging total patch changes 6 sec1.01.54.72.2-2.01.31.60.5-0.6-0.4-2.2-0.3-1.1-1.2-0.6-1.81.2-0.8-1.2-0.7-1.01.0-1.0-1.0-1.1-0.1
Patch foraging time to switch 0 sec5.711.727.3-2.51.9-0.7-0.91.4-1.53.05.22.94.14.33.44.9-4.03.74.23.33.7-3.54.14.14.12.2
Patch foraging water rate 0 sec2.04.28.61.3-1.00.40.4-0.91.1-2.0-2.9-1.7-2.6-2.5-1.9-2.82.4-2.1-2.6-1.9-2.22.1-2.6-2.6-2.5-1.4
Patch foraging water rate 12 sec0.40.73.21.8-1.71.81.41.1-1.10.9-0.80.60.40.10.5-0.5-0.10.30.00.40.1-0.20.30.30.10.5
Patch foraging water rate 18 sec0.50.82.51.3-1.10.90.80.1-0.3-0.4-1.6-0.5-0.9-1.1-0.6-1.41.1-0.8-1.2-0.6-0.91.0-0.5-0.5-0.7-0.2
Patch foraging water rate 24 sec0.50.72.71.5-1.40.71.60.6-1.2-0.0-1.30.1-0.7-0.8-0.2-1.00.8-0.3-0.9-0.1-0.60.60.30.3-0.00.4
Patch foraging water rate 6 sec2.33.38.62.0-1.61.01.1-0.30.1-1.5-2.9-1.2-2.3-2.3-1.5-2.72.2-1.7-2.3-1.8-2.12.1-1.7-1.7-2.0-1.0
Seeking ratio, delayed vs. immediate footshock0.30.41.6-1.01.0-1.3-0.8-0.90.5-0.9-0.0-0.7-0.5-0.6-0.7-0.20.4-0.6-0.5-0.4-0.40.4-0.4-0.4-0.10.3
Distance traveled before self-admin0.10.20.4-0.10.2-0.2-0.3-0.50.4-0.2-0.4-0.5-0.4-0.6-0.5-0.50.6-0.50.2-0.5-0.50.5-0.4-0.4-0.30.2
Distance traveled after self-admin0.10.10.5-0.30.3-0.2-0.3-0.10.00.30.3-0.00.30.20.00.2-0.10.10.7-0.00.0-0.20.30.30.10.3
Extensor digitorum longus weight2.07.720.24.2-4.34.54.04.0-3.23.00.03.22.22.43.00.9-2.42.72.22.72.2-2.21.21.21.20.8
Bone: elastic displacement1.51.72.90.3-0.50.80.71.2-1.01.61.21.41.71.71.41.3-1.41.41.51.51.6-1.51.01.01.51.4
Bone: elastic work2.63.45.01.2-1.41.71.62.1-1.72.21.32.22.12.22.21.7-2.02.12.02.22.2-2.21.21.21.81.3
Bone: endosteal estimation2.65.710.20.5-0.1-0.8-0.1-1.71.1-2.6-3.0-2.4-3.2-3.2-2.6-3.12.9-2.8-3.1-2.8-3.03.0-2.0-2.0-2.4-1.2
Bone: endosteal perimeter3.26.713.11.2-0.7-0.30.4-1.50.9-2.7-3.6-2.4-3.5-3.5-2.8-3.53.5-2.9-3.4-2.8-3.13.3-2.2-2.2-2.7-1.1
Epididymis fat weight0.51.62.60.2-0.40.80.51.1-0.91.61.31.31.61.61.41.4-1.41.41.51.31.3-1.51.21.21.41.2
Delta time in closed arm before/after self-admin0.50.51.10.8-0.90.90.90.9-1.10.60.10.80.50.50.70.3-0.50.70.20.70.7-0.60.80.80.4-0.1
Delta time in open arm before/after self-admin0.20.20.80.2-0.20.30.30.3-0.50.70.20.30.60.30.30.3-0.30.30.60.30.3-0.50.50.50.80.9
Diff in mean of infusions in LGA sessions0.30.41.1-1.01.0-0.9-1.0-0.91.0-0.70.1-0.7-0.5-0.3-0.6-0.10.5-0.50.1-0.5-0.50.6-0.7-0.7-0.1-0.0
Delay discount exponential model param1.21.32.9-0.40.20.3-0.10.8-0.70.61.71.21.21.71.31.7-1.71.40.51.21.5-1.41.41.41.00.1
Extinction: sum of active levers before priming3.74.09.22.7-2.83.02.82.8-2.82.20.22.31.51.72.10.8-1.62.01.21.91.5-1.41.71.71.31.0
Active lever presses in extinction session 61.81.86.82.5-2.52.62.32.0-1.81.3-0.51.40.60.81.2-0.0-0.81.10.60.90.5-0.40.40.40.20.3
Bone: final force0.10.20.50.4-0.4-0.10.70.3-0.70.2-0.20.20.3-0.20.1-0.10.00.1-0.40.40.6-0.50.60.60.60.7
Bone: final moment0.10.10.60.5-0.4-0.10.80.3-0.70.0-0.40.10.1-0.4-0.1-0.30.2-0.1-0.50.30.4-0.30.30.30.40.5
Food consumed during 24 hour testing period0.30.51.31.2-1.10.91.00.3-0.3-0.1-1.1-0.1-0.6-0.5-0.2-0.90.5-0.4-0.4-0.6-0.70.6-0.7-0.7-0.20.7
Glucose1.21.97.12.7-2.72.52.41.9-1.91.5-0.91.20.70.51.0-0.4-0.20.80.60.60.4-0.30.60.60.41.0
Heart weight0.40.61.91.4-1.31.30.70.4-0.2-0.2-1.1-0.1-0.8-0.3-0.1-0.90.5-0.3-0.6-0.7-0.91.1-0.6-0.6-1.1-0.4
Delay discount hyperbolic model param1.01.12.5-0.50.30.2-0.10.7-0.50.61.61.11.11.61.21.6-1.61.30.51.11.4-1.31.21.20.90.1
Intermittent access intake day 1-15 change1.32.64.51.8-1.92.12.02.1-2.12.00.41.81.61.21.70.8-1.41.61.71.61.4-1.21.61.61.70.5
Intermittent access intake escalation1.02.03.31.5-1.61.81.71.8-1.81.70.41.51.41.01.40.7-1.31.41.61.41.2-1.11.41.41.60.5
Intermittent access intake escalation 21.92.13.51.3-1.41.51.61.8-1.91.70.71.71.51.31.61.0-1.51.61.31.51.4-1.21.61.61.50.7
Intermitt. access day 1 inactive lever presses0.10.31.41.2-1.11.11.00.7-0.60.6-0.60.40.3-0.00.3-0.3-0.10.20.50.40.2-0.10.00.00.10.2
Intermitt. access day 15 inactive lever presses0.91.75.11.4-1.10.70.6-0.30.3-0.9-2.3-1.0-1.5-1.7-1.2-2.11.5-1.4-1.3-1.3-1.51.5-1.5-1.5-1.2-0.8
Intermitt. access escalation Index0.00.00.20.2-0.2-0.10.10.10.0-0.0-0.10.0-0.1-0.0-0.0-0.10.1-0.1-0.2-0.0-0.00.1-0.3-0.3-0.50.3
Intermittent access day 1 total infusions0.20.31.10.9-0.80.60.60.2-0.1-0.1-1.0-0.2-0.4-0.5-0.3-0.90.5-0.4-0.4-0.4-0.50.4-0.6-0.6-0.7-0.1
Intermittent access day 15 total infusions0.71.13.11.8-1.81.71.71.4-1.41.3-0.41.00.80.40.8-0.1-0.60.70.90.80.5-0.50.70.70.70.3
Intermittent access terminal intake (last 3 days)0.60.72.81.7-1.61.51.61.2-1.20.9-0.60.80.50.20.6-0.3-0.30.50.50.50.3-0.30.40.40.40.1
Intermittent access total infusions0.50.62.11.4-1.41.31.41.0-1.00.9-0.50.70.50.20.5-0.2-0.30.40.60.50.3-0.30.30.30.30.2
Intermittent access day 1 locomotion0.60.82.51.3-1.10.80.70.1-0.0-0.5-1.6-0.5-0.9-0.9-0.7-1.40.9-0.8-1.1-0.7-0.90.9-0.9-0.9-0.9-0.3
Intermittent access day 15 total locomotion0.71.32.41.4-1.51.41.51.5-1.41.30.21.31.10.91.20.5-1.11.10.81.21.1-1.00.90.91.10.6
Intermittent access total locomotion0.70.82.31.5-1.51.41.51.3-1.31.1-0.30.90.70.60.80.0-0.60.70.40.80.6-0.60.60.60.50.4
Intermittent access standard deviation0.30.62.41.5-1.41.51.41.0-1.00.7-0.60.60.20.20.5-0.3-0.20.40.60.50.2-0.20.20.20.4-0.4
Left kidney weight0.20.72.91.5-1.51.71.21.1-1.11.0-0.40.80.40.50.7-0.1-0.50.60.60.40.2-0.30.50.50.10.4
Right kidney weight0.21.02.31.2-1.31.51.21.3-1.31.40.11.10.90.81.00.4-0.80.91.10.70.5-0.50.90.90.81.2
Cocaine induced anxiety2.53.66.3-0.71.0-1.2-1.3-1.91.9-2.4-1.6-2.1-2.3-2.1-2.1-1.82.1-2.1-2.5-2.1-2.12.1-2.0-2.0-1.8-1.1
Post-drug Anxiety3.33.56.1-0.40.7-1.0-1.1-1.71.7-2.3-1.8-2.0-2.3-2.1-2.1-2.02.1-2.1-2.5-2.1-2.12.1-1.9-1.9-1.9-1.4
Baseline Anxiety0.60.71.50.2-0.30.50.50.7-0.81.20.70.81.10.80.90.8-0.80.91.20.80.8-0.81.11.10.70.4
Tail length0.83.29.12.9-3.02.92.92.5-2.62.0-0.51.91.21.11.60.1-1.11.41.11.30.9-0.91.31.30.81.1
Length with tail0.72.913.83.7-3.63.23.32.2-2.31.1-1.91.10.0-0.00.7-1.2-0.10.4-0.40.60.1-0.00.20.2-0.10.5
Length without tail0.72.26.62.0-1.71.31.1-0.00.2-0.9-2.6-0.9-1.6-1.6-1.1-2.31.5-1.4-1.7-1.2-1.51.4-1.7-1.7-1.6-0.3
Times rat made contact with spout0.80.92.9-0.40.3-0.20.20.4-0.81.11.00.71.10.90.81.0-0.90.80.90.70.8-0.91.21.21.71.7
Lifetime Intake0.60.72.21.5-1.51.31.41.2-1.11.1-0.40.80.60.40.7-0.1-0.40.60.70.60.4-0.40.50.50.40.4
Liver weight, left2.64.39.02.7-2.92.73.02.7-3.02.60.02.21.71.42.00.6-1.51.81.81.71.3-1.42.02.01.62.0
Liver weight, right2.84.86.51.4-1.72.02.12.5-2.22.51.62.52.32.42.51.9-2.32.52.52.32.3-2.31.51.52.52.5
Locomotor activity2.33.617.14.1-4.03.63.62.4-2.41.3-2.11.2-0.0-0.10.8-1.4-0.20.5-0.40.5-0.10.10.20.20.00.2
Locomotor testing distance1.73.011.23.3-3.33.33.02.5-2.21.7-1.01.70.70.91.4-0.3-1.01.20.31.00.6-0.60.70.70.40.3
Locomotor testing rearing2.75.412.53.1-3.23.53.13.2-2.92.80.42.71.92.22.51.0-2.32.32.02.11.6-1.61.91.91.30.9
Locomotion in novel chamber1.01.33.6-1.41.2-1.1-0.50.1-0.30.51.90.81.21.10.91.7-1.21.11.01.31.5-1.31.21.21.40.4
Locomotion in novel chamber post-restriction1.01.63.0-1.31.4-1.6-1.4-1.71.7-1.2-0.6-1.6-1.1-1.2-1.5-0.91.1-1.4-0.6-1.5-1.41.2-1.2-1.2-0.80.1
Fecal boli incidents, locomotor time 11.11.55.01.7-1.82.21.61.9-1.20.50.31.60.51.41.50.7-1.11.40.81.31.1-1.10.20.20.0-0.7
Change in fecal boli incidents, locomotor task0.20.20.70.3-0.40.10.50.4-0.70.80.10.40.60.30.30.2-0.30.30.50.50.4-0.40.60.60.30.8
Time >=10cm from walls, locomotor time 10.20.20.80.9-0.80.50.70.4-0.90.3-0.60.1-0.1-0.3-0.0-0.50.2-0.1-0.30.10.10.00.70.7-0.4-0.1
Bouts of movement, locomotor time 11.11.32.80.7-0.50.3-0.1-0.60.8-0.4-1.7-1.1-1.0-1.3-1.2-1.61.4-1.2-1.5-1.1-1.31.2-1.6-1.6-1.2-0.5
Total resting periods, locomotor time 11.51.73.50.7-0.40.2-0.2-0.71.0-0.6-1.8-1.2-1.2-1.5-1.4-1.81.6-1.4-1.4-1.3-1.51.4-1.9-1.9-1.4-0.6
Rest time, locomotor task time 13.13.96.80.00.3-0.5-1.2-1.71.9-1.6-2.2-2.2-2.1-2.1-2.2-2.42.3-2.3-1.9-2.3-2.42.2-2.3-2.3-2.6-1.5
Distance moved, locomotor task time 11.42.25.50.2-0.40.41.11.3-1.81.31.51.61.51.41.61.6-1.71.61.01.71.7-1.32.32.31.60.8
Vertical activity count, locomotor time 11.02.43.90.4-0.70.81.31.6-1.81.11.51.81.51.81.81.7-2.01.81.61.71.8-1.81.91.91.10.9
Time >=10cm from walls, locomotor time 20.50.82.41.5-1.51.31.41.2-1.50.5-0.30.90.20.40.80.0-0.50.7-0.00.80.5-0.01.01.00.00.1
Bouts of movement, locomotor time 20.30.40.8-0.00.1-0.4-0.3-0.60.6-0.3-0.8-0.8-0.5-0.8-0.8-0.80.8-0.8-0.2-0.9-0.90.8-0.9-0.9-0.70.2
Total resting periods, locomotor time 20.20.30.5-0.20.3-0.4-0.5-0.60.6-0.3-0.5-0.7-0.4-0.6-0.7-0.60.6-0.7-0.1-0.7-0.70.6-0.7-0.7-0.7-0.0
Rest time, locomotor task time 20.10.11.0-0.10.10.0-0.4-0.10.2-0.3-0.0-0.1-0.1-0.1-0.1-0.00.1-0.10.4-0.10.0-0.20.00.0-0.8-1.0
Distance moved, locomotor task time 20.20.20.60.4-0.4-0.00.60.1-0.70.3-0.4-0.1-0.2-0.3-0.1-0.40.3-0.2-0.7-0.2-0.40.70.60.60.30.7
Vertical activity count, locomotor time 20.10.22.3-0.30.3-0.5-0.1-0.30.00.1-0.0-0.30.0-0.0-0.2-0.10.1-0.2-0.3-0.4-0.40.3-0.0-0.00.51.5
Light reinforcement 10.41.02.00.8-1.01.40.91.2-1.01.10.71.20.81.31.30.9-1.01.21.20.90.6-0.70.80.80.90.7
Light reinforcement 22.03.14.9-1.21.3-1.3-1.7-1.92.1-2.2-1.0-2.0-2.1-1.6-1.8-1.31.7-1.8-1.5-2.1-2.12.2-1.9-1.9-1.6-1.0
Bone: marrow area2.65.710.40.6-0.1-0.7-0.1-1.71.1-2.6-3.1-2.4-3.2-3.2-2.6-3.12.9-2.8-3.1-2.8-3.03.0-2.1-2.1-2.4-1.3
Bone: maximum diameter4.38.116.91.8-1.30.20.8-1.31.0-2.8-4.1-2.4-3.7-3.7-2.8-3.93.7-3.1-3.5-3.0-3.33.5-3.0-3.0-3.2-1.3
Bone: maximum force0.20.41.30.7-0.5-0.00.7-0.0-0.3-0.6-1.1-0.3-0.7-1.0-0.6-1.00.7-0.6-1.1-0.2-0.20.3-0.2-0.2-0.20.0
Bone: maximum moment0.30.51.70.7-0.5-0.10.7-0.1-0.2-0.8-1.2-0.5-0.8-1.2-0.7-1.10.9-0.8-1.3-0.3-0.30.4-0.4-0.4-0.3-0.1
Mean time between licks in bursts0.00.00.60.2-0.10.10.10.0-0.1-0.2-0.2-0.0-0.1-0.2-0.1-0.20.2-0.1-0.20.20.1-0.10.10.1-0.4-0.7
Mean num. licks in bursts0.20.30.60.4-0.40.50.50.7-0.70.50.40.70.60.50.70.5-0.50.70.50.80.8-0.80.60.60.4-0.4
Cd content in liver2.12.44.91.4-1.51.51.81.8-2.12.20.61.71.81.11.50.9-1.21.51.11.61.4-1.41.81.81.71.2
Co content in liver0.60.71.40.9-0.90.91.21.1-0.90.50.41.10.60.71.00.6-0.80.90.81.11.0-1.00.30.30.60.5
Cu content in liver0.40.51.5-1.00.9-0.8-0.5-0.00.00.01.20.40.60.70.51.1-0.70.60.60.70.9-0.80.50.50.90.2
Fe content in liver0.50.61.9-1.31.1-0.7-1.0-0.30.40.01.40.30.60.90.51.2-0.80.60.90.50.6-0.70.50.50.4-0.0
K content in liver3.93.713.1-3.53.6-3.6-3.1-2.82.5-2.10.7-2.0-1.1-1.1-1.70.01.1-1.5-1.2-1.3-0.70.9-1.0-1.00.10.0
Mg content in liver2.82.912.0-3.43.5-3.3-3.0-2.42.1-1.31.1-1.6-0.4-0.7-1.30.50.6-1.0-0.8-0.9-0.30.4-0.3-0.30.5-0.1
Mn content in liver3.53.96.9-2.02.2-2.5-2.1-2.62.1-2.0-1.0-2.5-1.7-2.2-2.4-1.52.2-2.3-2.3-2.1-1.81.9-1.3-1.3-1.0-0.8
Na content in liver1.81.97.0-2.62.4-1.9-2.0-1.00.80.72.2-0.11.41.00.31.7-1.00.50.90.71.0-1.11.11.11.70.9
Rb content in liver0.91.05.1-2.32.2-2.0-1.8-1.31.1-0.41.2-0.70.20.0-0.40.7-0.1-0.2-0.0-0.10.2-0.20.20.20.5-0.1
Se content in liver1.61.88.5-2.92.9-2.3-2.8-1.81.8-0.71.5-0.90.10.1-0.61.00.0-0.40.1-0.5-0.20.10.20.2-0.1-1.0
Sr content in liver0.80.71.50.8-0.91.00.81.0-1.01.20.30.91.00.80.90.5-0.70.80.80.80.7-0.81.01.00.5-0.0
Zn content in liver0.10.20.5-0.70.7-0.7-0.7-0.60.6-0.30.1-0.4-0.1-0.3-0.40.00.2-0.3-0.3-0.3-0.20.1-0.3-0.30.10.2
Bone: minimum diameter1.01.95.21.7-1.40.71.30.1-0.5-1.1-2.3-0.7-1.7-1.8-1.0-2.01.9-1.2-1.8-1.1-1.31.6-0.7-0.7-1.4-0.9
Time in familiar zone, hab. session 11.41.42.80.3-0.40.80.31.1-1.01.41.11.21.51.31.31.2-1.71.31.21.41.3-1.61.41.40.5-0.6
Time in novel zone, hab. session 10.80.82.30.3-0.1-0.30.1-0.60.3-0.8-1.1-0.8-1.1-1.1-0.9-1.21.5-1.0-0.9-1.0-1.11.3-0.8-0.8-0.40.5
Total zone transitions, hab. session 12.12.95.6-2.12.2-2.4-2.2-2.32.3-2.1-0.4-2.0-1.6-1.4-1.9-0.91.2-1.7-1.6-1.7-1.51.3-1.6-1.6-0.9-0.3
Total locomotion distance, hab. session 11.11.66.6-2.62.5-2.3-2.4-1.81.9-1.21.0-1.2-0.4-0.2-0.90.50.2-0.7-0.4-0.7-0.40.2-0.5-0.5-0.1-0.1
Locomotion velocity, hab. session 11.92.77.0-2.62.6-2.5-2.6-2.32.5-2.00.3-1.8-1.2-0.8-1.5-0.20.9-1.3-1.1-1.4-1.11.0-1.4-1.4-0.7-0.4
Time in familiar zone, hab. session 21.51.63.1-0.40.20.5-0.30.8-0.31.41.71.21.81.71.41.7-1.31.51.71.61.6-1.71.01.00.9-0.2
Time in novel zone, hab. session 22.02.14.41.0-0.70.20.5-0.60.5-1.4-2.1-1.2-1.9-1.7-1.4-2.01.6-1.5-1.6-1.7-1.81.9-1.6-1.6-1.5-0.2
Total zone transitions, hab. session 24.55.89.9-2.52.7-3.0-2.8-3.22.9-2.8-0.9-2.9-2.4-2.1-2.7-1.52.0-2.6-2.2-2.8-2.52.4-2.0-2.0-1.4-0.4
Total locomotion distance, hab. session 23.64.79.0-2.52.6-2.6-2.9-2.93.0-2.5-0.6-2.6-2.0-1.6-2.3-1.21.6-2.2-1.8-2.4-2.02.0-2.0-2.0-1.6-0.8
Locomotion velocity, hab. session 24.15.49.8-2.62.8-2.9-3.0-3.13.1-2.8-0.7-2.8-2.2-1.9-2.5-1.31.8-2.4-2.0-2.5-2.22.1-2.1-2.1-1.7-1.0
Novel to familiar place preference ratio0.50.61.50.6-0.40.00.3-0.30.2-0.6-1.2-0.7-0.9-1.1-0.8-1.20.9-0.9-1.0-0.8-0.80.8-0.8-0.8-0.7-0.3
Novelty place preference1.21.23.31.0-0.80.30.6-0.30.2-0.9-1.8-0.9-1.3-1.5-1.1-1.71.4-1.2-1.4-1.1-1.21.2-1.2-1.2-1.1-0.5
Time in novel zone, NPP test0.80.92.71.1-0.90.50.7-0.10.0-0.6-1.6-0.6-1.0-1.2-0.8-1.51.1-1.0-1.1-0.8-0.90.9-1.0-1.0-0.9-0.3
Total zone transitions, NPP test1.31.93.4-1.51.6-1.7-1.7-1.81.5-1.6-0.4-1.7-1.5-1.2-1.5-0.81.2-1.4-1.2-1.7-1.71.6-0.6-0.6-0.8-0.2
Total locomotion distance, NPP test1.72.34.2-1.81.9-2.0-1.9-2.11.8-1.9-0.4-1.8-1.6-1.2-1.7-0.81.2-1.6-1.4-1.9-1.71.6-1.0-1.0-0.8-0.1
Locomotion velocity, NPP test1.21.73.3-1.71.7-1.8-1.7-1.81.5-1.6-0.2-1.6-1.3-1.0-1.4-0.61.0-1.3-1.1-1.6-1.51.4-0.7-0.7-0.6-0.1
Intraocular pressure0.91.32.71.5-1.61.61.61.5-1.51.30.11.31.00.91.20.5-1.01.10.91.11.0-0.90.80.80.70.4
Delta distance traveled before/after self-admin0.00.00.1-0.40.3-0.3-0.4-0.20.30.00.3-0.10.20.20.00.2-0.10.00.3-0.1-0.1-0.0-0.1-0.1-0.2-0.2
Delta ambulatory time before/after self-admin0.10.10.4-0.70.6-0.5-0.6-0.30.30.10.5-0.00.30.40.10.4-0.20.10.40.00.0-0.10.20.2-0.2-0.1
Parametrial fat weight5.111.916.61.7-2.22.92.53.7-3.54.12.84.04.03.84.03.3-3.74.03.54.14.0-3.83.53.53.31.6
Pavlov. Cond. lever latency0.70.91.60.5-0.60.51.01.2-1.20.80.81.30.90.81.11.0-1.21.20.91.21.2-1.01.01.00.6-0.5
Pavlov. Cond. magazine entry latency1.01.35.1-2.12.1-1.7-2.3-1.71.9-0.70.5-1.3-0.2-0.3-1.00.10.7-0.9-0.2-0.9-0.60.5-0.6-0.6-0.20.6
Pavlov. Cond. change in total contacts1.51.62.7-0.80.9-0.8-1.3-1.61.6-1.0-0.9-1.6-1.1-1.1-1.5-1.21.4-1.5-1.1-1.5-1.51.3-1.4-1.4-0.71.0
Pavlov. Cond. index score1.21.53.7-1.51.6-1.3-1.9-1.81.9-1.0-0.3-1.6-0.8-0.8-1.4-0.71.2-1.3-0.8-1.3-1.21.1-1.1-1.1-0.50.7
Pavlov. Cond. latency score1.31.63.5-1.51.5-1.3-1.9-1.81.8-1.0-0.4-1.7-0.9-0.9-1.4-0.81.3-1.4-0.9-1.5-1.31.2-1.1-1.1-0.60.7
Pavlov. Cond. lever contacts0.30.40.8-0.50.5-0.3-0.9-0.80.9-0.3-0.3-0.8-0.4-0.3-0.7-0.50.6-0.7-0.3-0.8-0.80.6-0.6-0.6-0.20.8
Pavlov. Cond. magazine entry number1.51.95.62.0-2.01.72.42.0-2.21.0-0.01.70.70.81.40.4-1.21.30.71.31.1-0.91.11.10.7-0.4
Pavlov. Cond. intertrial magazine entries1.31.63.11.3-1.51.41.81.7-1.41.20.51.51.01.31.50.8-1.21.41.21.41.2-1.20.50.51.31.3
Pavlov. Cond. lever-magazine prob. diff.1.01.33.3-1.51.5-1.3-1.8-1.71.7-0.9-0.1-1.5-0.6-0.7-1.2-0.51.0-1.2-0.7-1.2-1.10.9-0.9-0.9-0.30.8
Pavlov. Cond. response bias1.11.43.8-1.61.6-1.3-2.0-1.71.8-0.9-0.2-1.5-0.6-0.7-1.3-0.51.1-1.2-0.7-1.2-1.00.9-0.9-0.9-0.50.6
Pavlov. Cond. lever latency0.60.92.7-1.21.1-0.9-0.6-0.0-0.50.31.50.50.80.80.61.3-0.80.70.70.70.9-0.71.71.71.00.2
Pavlov. Cond. magazine entry latency0.30.30.9-0.40.4-0.2-0.7-0.60.9-0.6-0.2-0.6-0.6-0.3-0.4-0.30.2-0.5-0.0-0.7-0.70.4-1.0-1.0-0.70.0
Pavlov. Cond. change in total contacts0.50.92.61.6-1.51.61.00.40.10.1-1.5-0.2-0.6-0.4-0.3-1.20.5-0.4-0.5-0.6-0.90.7-1.4-1.4-0.80.1
Pavlov. Cond. index score0.60.72.71.1-1.01.10.50.10.5-0.2-1.3-0.4-0.7-0.5-0.4-1.10.6-0.6-0.4-0.8-1.00.7-1.6-1.6-0.90.2
Pavlov. Cond. latency score0.70.93.31.0-0.90.90.3-0.10.7-0.5-1.4-0.6-0.9-0.7-0.6-1.20.7-0.8-0.6-1.0-1.10.9-1.8-1.8-1.20.0
Pavlov. Cond. lever contacts0.40.62.01.1-1.01.00.60.20.3-0.2-1.2-0.3-0.5-0.6-0.4-1.10.5-0.5-0.5-0.5-0.70.4-1.4-1.4-0.8-0.2
Pavlov. Cond. magazine entry number0.70.92.4-0.70.5-0.4-0.20.4-0.70.71.30.81.11.00.81.3-0.80.90.71.01.2-1.01.51.51.0-0.0
Pavlov. Cond. intertrial magazine entries0.20.31.2-0.40.4-0.80.2-0.1-0.60.10.30.10.20.00.00.20.10.1-0.10.10.4-0.30.90.91.01.1
Pavlov. Cond. lever-magazine prob. diff.0.70.93.21.2-1.11.10.50.00.6-0.3-1.4-0.5-0.8-0.6-0.5-1.20.7-0.7-0.4-0.9-1.10.8-1.8-1.8-1.00.3
Pavlov. Cond. response bias0.30.51.71.0-0.90.90.50.10.4-0.1-1.1-0.3-0.5-0.5-0.4-0.90.5-0.5-0.4-0.5-0.60.4-1.3-1.3-0.70.0
Time in closed arm before self-admin0.40.52.4-1.61.5-1.3-1.2-0.70.8-0.31.1-0.20.20.3-0.00.8-0.30.10.20.10.2-0.10.10.10.40.0
Time in closed arm after self-admin0.30.31.2-1.11.0-0.9-0.8-0.30.3-0.21.00.10.20.50.20.8-0.50.30.20.40.5-0.30.40.40.4-0.5
Time in open arm before self-admin0.40.41.10.3-0.2-0.00.1-0.30.3-0.8-0.8-0.5-1.0-0.6-0.6-0.80.8-0.6-1.0-0.6-0.81.0-0.7-0.7-0.8-0.5
Time in open arm after self-admin0.30.30.7-0.70.7-0.7-0.8-0.90.6-0.4-0.3-0.8-0.4-0.6-0.7-0.40.7-0.7-0.4-0.7-0.60.5-0.1-0.1-0.10.2
Bone: periosteal estimation2.85.812.71.5-1.1-0.10.8-1.10.6-2.5-3.6-2.0-3.2-3.3-2.5-3.43.1-2.7-3.3-2.5-2.82.9-2.2-2.2-2.4-1.0
Bone: periosteal perimeter1.83.08.21.7-1.40.51.2-0.3-0.2-1.4-2.9-1.2-2.2-2.4-1.6-2.62.3-1.8-2.4-1.6-1.92.1-1.3-1.3-1.7-0.5
Bone: post-yield work0.81.14.00.2-0.0-0.2-0.1-0.60.6-1.4-1.2-0.9-1.4-1.3-1.0-1.20.9-1.0-1.4-0.8-0.91.0-1.0-1.0-1.4-2.0
Progressive ratio test 1 active lever presses0.50.72.61.6-1.51.21.20.5-0.4-0.1-1.4-0.1-0.6-0.6-0.3-1.20.6-0.4-0.6-0.3-0.50.6-0.6-0.6-0.8-0.4
Progressive ratio test 1 breakpoint0.60.72.71.6-1.51.11.20.5-0.4-0.1-1.5-0.2-0.7-0.7-0.4-1.30.7-0.5-0.7-0.4-0.60.7-0.7-0.7-0.9-0.4
Progressive ratio test 1 inactive lever presses0.50.73.11.8-1.61.51.30.7-0.60.3-1.30.1-0.3-0.4-0.1-1.00.4-0.2-0.4-0.1-0.40.4-0.4-0.4-0.60.0
Progressive ratio test 2 active lever presses0.00.00.1-0.00.1-0.2-0.0-0.20.10.0-0.2-0.2-0.0-0.2-0.2-0.20.2-0.20.2-0.2-0.20.2-0.1-0.1-0.20.1
Progressive ratio test 2 breakpoint0.00.00.1-0.00.0-0.20.0-0.10.10.1-0.1-0.10.1-0.1-0.1-0.10.1-0.10.3-0.1-0.00.1-0.0-0.0-0.10.1
Progressive ratio test 2 inactive lever presses0.20.30.91.0-0.90.60.70.2-0.20.2-1.0-0.2-0.2-0.3-0.3-0.80.4-0.30.2-0.3-0.50.5-0.4-0.4-0.50.1
Incentive Sensitization - Responses0.71.04.9-2.22.1-1.8-1.7-1.00.9-0.11.5-0.30.60.4-0.11.1-0.50.10.90.00.4-0.40.50.50.60.3
Incentive Sensitization - Breakpoint0.70.94.1-2.01.9-1.6-1.5-0.80.70.11.5-0.10.70.50.11.2-0.60.31.00.20.5-0.50.70.70.80.4
Sum of active levers in priming session hrs 5-60.80.73.51.6-1.61.91.41.3-1.00.4-0.30.90.10.70.90.0-0.40.7-0.10.60.3-0.10.00.0-0.1-0.2
Progressive ratio1.42.24.3-1.92.0-2.1-2.1-2.02.0-1.6-0.3-1.8-1.3-1.3-1.6-0.71.2-1.5-1.0-1.5-1.21.2-1.2-1.2-1.1-0.4
Food seeking constrained by brief footshock0.60.71.2-0.40.5-1.0-0.2-0.90.8-0.9-0.8-0.9-1.0-1.1-1.0-0.90.9-1.0-0.7-0.9-0.90.9-1.1-1.1-0.50.4
Seeking ratio, punishment vs. effort0.40.61.71.1-1.21.11.31.1-1.00.9-0.10.90.60.60.80.2-0.60.70.50.60.5-0.50.40.40.70.7
Retroperitoneal fat weight2.711.717.20.4-0.92.01.33.0-2.84.03.73.74.14.13.94.0-3.84.04.03.93.9-3.83.93.93.61.5
Reaction time number correct0.40.81.40.2-0.30.60.60.9-1.00.90.91.00.91.01.01.0-1.01.00.91.10.9-0.81.21.20.90.1
Reaction time mean minus median1.53.812.8-3.53.6-3.6-3.4-2.92.6-1.60.7-2.1-0.8-1.2-1.8-0.01.1-1.6-1.0-1.5-1.01.0-0.4-0.4-0.3-0.4
Reaction time mean minus median AUC1.12.79.3-3.03.0-2.9-2.9-2.52.1-1.30.6-1.8-0.6-1.0-1.5-0.00.9-1.3-0.7-1.2-0.80.9-0.1-0.1-0.2-0.7
Reaction time num false alarms0.40.61.60.10.0-0.3-0.2-0.70.3-0.6-1.0-0.9-0.8-1.0-0.9-1.10.8-1.0-1.3-0.8-0.90.9-0.6-0.6-0.10.4
Reaction time num false alarms AUC0.40.72.20.00.1-0.5-0.3-0.80.4-0.7-1.1-1.0-0.9-1.2-1.1-1.10.9-1.1-1.5-0.8-0.91.0-0.6-0.6-0.20.0
Reaction time trials correct on left0.40.81.40.2-0.30.60.60.9-1.00.90.91.00.91.01.01.0-1.01.00.91.10.9-0.81.21.20.90.1
Reaction time trials on left0.30.61.10.1-0.20.40.40.7-0.80.80.80.80.80.80.90.9-0.90.90.80.90.8-0.61.01.00.80.1
Reaction time mean0.50.93.6-1.91.8-1.4-1.8-1.01.00.21.2-0.40.80.2-0.20.9-0.4-0.00.30.20.5-0.50.70.70.7-0.0
Reaction time mean AUC0.60.93.6-1.91.8-1.4-1.8-0.90.90.41.4-0.20.90.40.01.1-0.70.20.60.30.7-0.60.80.80.90.2
Median of all reaction times0.50.71.5-1.11.0-0.5-1.0-0.20.30.81.20.21.20.70.41.0-0.90.50.70.71.0-0.90.90.90.90.1
Reaction time omissions3.45.08.6-2.42.6-2.9-2.7-2.92.9-2.6-0.8-2.6-2.2-2.1-2.5-1.31.9-2.4-1.8-2.4-2.12.1-2.0-2.0-1.4-0.9
Reaction time false alarm rate0.81.12.50.2-0.0-0.3-0.3-0.90.7-0.9-1.4-1.2-1.1-1.4-1.3-1.51.2-1.3-1.6-1.1-1.21.2-1.1-1.1-0.7-0.0
Reaction time premature initiation rate0.20.31.00.9-0.80.50.60.2-0.2-0.2-1.0-0.2-0.6-0.5-0.4-0.90.6-0.4-0.8-0.5-0.50.5-0.2-0.2-0.7-0.5
Reaction time premature initiations0.10.20.80.9-0.90.60.80.5-0.70.2-0.50.3-0.1-0.00.1-0.30.00.1-0.40.1-0.00.10.40.4-0.1-0.3
Std. dev. reaction times1.52.79.2-3.03.0-3.0-2.9-2.52.2-1.20.6-1.8-0.6-1.1-1.6-0.00.8-1.4-0.8-1.2-0.70.7-0.3-0.3-0.1-0.4
Reaction time trials completed0.30.61.10.1-0.20.40.40.7-0.80.80.80.80.80.80.90.9-0.90.90.80.90.8-0.61.01.00.80.1
Reaction time trials AUC0.40.81.40.3-0.40.70.60.9-1.01.00.81.01.01.01.01.0-1.11.10.91.10.9-0.81.21.20.80.1
Run reversals in cocaine runway, females2.72.74.7-1.51.7-1.7-1.9-1.92.2-2.1-0.5-1.7-1.7-1.3-1.6-0.91.4-1.6-1.9-1.6-1.41.4-1.7-1.7-1.4-1.6
Run reversals in cocaine runway, males0.30.30.80.3-0.30.20.60.5-0.80.40.20.50.30.30.40.3-0.30.4-0.20.60.5-0.30.90.90.90.4
Latency to leave start box in cocaine runway0.10.10.8-0.60.5-0.4-0.5-0.20.00.10.50.00.30.30.10.4-0.30.20.20.10.2-0.20.20.20.40.9
Latency to leave start box in cocaine runway, F0.10.20.8-0.90.8-0.7-0.7-0.40.2-0.20.6-0.10.20.2-0.00.4-0.10.10.00.00.1-0.10.20.20.30.6
Latency to leave start box in cocaine runway, M0.40.41.00.1-0.20.40.30.5-0.50.80.60.60.80.80.70.6-0.80.71.00.50.6-0.70.40.40.81.0
Std. dev. time between licks in bursts0.20.31.2-1.00.9-0.5-1.1-0.40.6-0.30.8-0.10.20.40.10.6-0.40.20.40.20.3-0.40.20.2-0.4-1.0
Total sessions with >9 infusions0.40.41.31.1-1.11.11.10.9-0.80.8-0.20.70.50.40.6-0.0-0.30.50.50.50.4-0.40.30.30.30.3
Short access day 1 total inactive lever presses5.77.612.43.0-3.33.53.43.5-3.43.40.83.12.72.42.91.5-2.52.82.42.82.4-2.62.42.42.31.9
Short access day 10 total inactive lever presses0.10.10.70.8-0.80.70.60.4-0.40.1-0.60.1-0.1-0.10.0-0.50.0-0.0-0.20.0-0.10.2-0.1-0.10.10.0
Short access day 1 total infusions1.82.45.62.3-2.42.32.32.2-2.11.8-0.01.71.31.21.60.4-1.21.41.01.41.1-1.21.01.01.01.2
Short access day 10 total infusions0.10.10.50.6-0.60.70.60.5-0.40.4-0.10.30.30.20.30.0-0.20.30.40.30.2-0.30.20.20.3-0.0
Short access total infusions1.01.22.21.2-1.31.31.41.4-1.41.50.31.31.21.01.20.6-1.01.11.21.11.0-1.01.01.00.80.9
Short access day 1 locomotion0.70.91.61.0-1.11.21.11.2-1.11.20.31.01.00.81.00.5-0.80.91.00.90.8-0.80.70.70.71.0
Short access day 10 total locomotion0.10.30.60.3-0.30.60.40.5-0.40.40.30.50.50.70.50.4-0.60.60.30.70.6-0.60.40.40.80.0
Short access total locomotion0.40.51.10.8-0.81.00.90.9-0.80.80.10.70.60.60.70.3-0.60.70.40.80.7-0.60.50.50.70.4
One hour access (0.3 mA shock)0.80.94.52.1-2.01.81.81.2-1.20.8-1.20.50.1-0.20.3-0.80.10.10.20.3-0.00.10.10.1-0.10.1
Compulsive drug intake2.53.04.4-0.30.6-1.1-1.0-1.71.6-1.8-1.8-1.9-2.0-2.1-2.0-1.92.0-2.0-2.0-2.0-2.01.9-1.8-1.8-2.0-0.8
One hour access (shock baseline)0.91.52.31.1-1.21.51.41.5-1.51.40.51.31.21.11.30.8-1.21.21.31.31.1-0.91.21.21.30.4
Social response proportion0.30.41.10.8-0.70.11.10.2-0.2-0.7-0.9-0.1-0.8-0.6-0.3-0.80.7-0.4-0.9-0.4-0.40.4-0.9-0.90.10.5
Social responses0.30.41.31.0-0.90.60.70.10.0-0.3-1.2-0.3-0.6-0.5-0.4-1.00.8-0.6-0.5-0.6-0.60.4-0.9-0.9-0.60.2
Social time0.70.94.02.0-2.01.81.91.4-1.20.7-0.70.90.20.30.7-0.3-0.30.60.30.50.2-0.30.10.10.00.0
Soleus weight0.51.43.91.6-1.31.00.90.10.0-0.9-2.0-0.6-1.3-1.2-0.8-1.71.0-1.0-1.4-0.9-1.11.1-1.3-1.3-1.5-1.3
Bone: stiffness0.91.53.7-0.40.6-1.3-0.3-1.20.6-1.7-1.2-1.3-1.5-1.9-1.5-1.41.6-1.5-1.9-1.1-1.01.1-0.7-0.7-0.5-0.0
Tibialis anterior weight2.69.022.74.6-4.84.64.74.3-3.93.1-0.33.42.12.23.00.7-2.42.71.92.82.3-2.21.71.71.61.3
Time to tail flick, vehicle, before self-admin0.80.91.7-0.50.6-0.8-0.7-0.90.9-1.2-0.6-0.9-1.1-1.0-1.0-0.81.0-1.0-1.0-0.8-0.71.1-0.9-0.9-1.3-1.1
Time to tail flick, vehicle, after self-admin1.52.03.2-0.10.3-0.6-0.7-1.21.3-1.6-1.5-1.5-1.7-1.7-1.5-1.61.5-1.6-1.6-1.6-1.61.6-1.8-1.8-1.2-0.6
Time to tail flick, test, before self-admin1.11.22.10.8-1.01.21.11.3-1.11.30.71.31.21.21.30.9-1.11.21.41.21.1-1.10.90.90.60.6
Time to tail flick, test, after self-admin0.50.52.21.5-1.51.31.31.0-0.90.8-0.60.60.20.10.4-0.3-0.00.30.80.30.10.10.00.0-0.6-0.2
Delta time to tail flick, vehicle, before/after SA0.90.81.3-0.20.3-0.5-0.6-0.90.9-1.0-1.0-1.0-1.0-1.1-1.1-1.01.0-1.1-1.0-1.1-1.10.9-1.1-1.1-0.6-0.2
Delta time to tail flick, test, before/after SA0.40.40.7-0.20.3-0.5-0.4-0.60.5-0.5-0.6-0.7-0.6-0.9-0.8-0.70.8-0.8-0.2-0.8-0.80.8-0.5-0.5-0.7-0.5
Tibia length0.71.95.32.1-1.91.51.30.30.1-0.3-2.3-0.6-1.2-1.3-0.8-2.01.3-1.0-0.9-1.1-1.31.3-1.8-1.8-1.8-0.9
Ambulatory time before self-admin0.10.20.50.10.0-0.1-0.1-0.40.3-0.3-0.6-0.5-0.5-0.7-0.6-0.70.7-0.6-0.0-0.6-0.60.6-0.5-0.5-0.40.2
Ambulatory time after self-admin0.20.20.8-0.20.10.1-0.10.2-0.30.70.60.30.70.60.40.6-0.40.40.90.40.4-0.40.70.70.30.5
Bone: tissue strength0.50.51.8-0.0-0.1-0.00.40.5-0.40.50.70.70.70.70.70.7-0.80.70.70.70.9-0.80.20.21.11.4
Total heroin consumption1.01.15.12.3-2.22.22.01.4-1.40.7-1.00.8-0.10.20.6-0.6-0.00.4-0.20.40.00.30.00.0-0.10.3
Bone: trabecular number2.84.79.12.5-2.62.62.72.8-3.02.60.52.52.01.92.31.1-2.02.11.52.11.8-2.02.32.31.50.8
Bone: trabecular spacing1.31.88.6-2.92.8-2.4-2.3-1.41.5-0.41.9-0.50.50.6-0.21.4-0.60.10.50.20.6-0.50.20.21.10.6
Bone: trabecular thickness0.60.83.31.8-1.81.61.61.2-1.30.9-0.70.70.30.20.6-0.4-0.30.40.10.40.1-0.30.40.40.00.5
Bone: trabecular tissue density2.53.77.9-2.22.4-2.3-2.6-2.52.8-2.3-0.4-2.2-1.6-1.5-2.0-0.91.5-1.8-1.6-1.8-1.41.3-2.1-2.1-1.5-1.4
Water consumed over 24 hours1.41.83.71.4-1.51.61.81.7-1.91.70.41.51.21.21.40.8-1.21.31.21.00.9-0.81.51.51.31.3
Number of responses in last shaping day0.70.81.80.7-0.81.30.81.1-0.90.70.51.00.70.91.00.7-0.91.00.41.00.8-1.00.70.71.3-0.1