Hub : Genes

Nubpl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr6_69771404_69775195 0.06 0.04 3.5e-06 0.05 0.06 0.05 0.05 8.6e-06 6.3e-07 2.0e-06 4.3e-06
2 Brain intron excision ratio chr6_69771404_69775195 0.12 0.12 7.9e-04 0.04 0.03 0.03 0.03 1.1e-04 2.2e-03 1.8e-03 2.0e-03
3 pVTA intron excision ratio chr6_69771404_69775195 0.1 0.07 2.4e-03 0.04 0.03 0.03 0.03 6.9e-03 1.9e-02 2.4e-02 2.0e-02
4 PL mRNA stability Nubpl 0.07 0.05 1.7e-07 0.05 0.06 0.06 0.06 3.6e-06 2.2e-07 1.2e-07 3.4e-07
5 Adipose intron excision ratio chr6_69771404_69775195 0.03 0.02 1.0e-03 0.01 0.03 0.02 0.01 1.9e-02 7.8e-04 3.5e-03 6.8e-03
6 Adipose gene expression Nubpl 0.04 0.03 3.5e-04 0.01 0.03 0.01 0.02 2.1e-02 2.5e-04 1.7e-02 1.4e-03
7 PL gene expression Nubpl 0.19 0.1 0.0e+00 0.13 0.16 0.16 0.16 2.5e-14 4.6e-17 1.9e-17 4.3e-17
8 OFC gene expression Nubpl 0.66 0.26 7.6e-06 0.1 0.17 0.16 0.2 1.8e-03 7.3e-05 9.8e-05 1.7e-05
9 NAcc mRNA stability Nubpl 0.05 0.03 2.3e-06 0.02 0.04 0.04 0.03 1.2e-03 1.4e-05 3.7e-05 8.2e-05
10 Liver intron excision ratio chr6_69775277_69781004 0.03 0.02 3.0e-03 0.01 0.02 0.01 0.02 9.6e-03 2.1e-03 6.7e-02 5.5e-03
11 Brain intron excision ratio chr6_69562087_69609481 0.09 0.06 6.2e-07 0.06 0.08 0.07 0.07 3.6e-06 1.5e-07 2.6e-07 4.7e-07
12 NAcc intron excision ratio chr6_69562087_69609481 0.07 0.04 4.3e-08 0.07 0.07 0.06 0.07 8.1e-09 3.9e-08 1.5e-07 5.7e-09
13 Brain gene expression Nubpl 0.08 0.05 6.7e-07 0.07 0.07 0.06 0.07 7.2e-07 2.0e-07 3.2e-06 5.3e-07
14 BLA alternative TSS XM_008764655.3 0.05 0.04 7.7e-03 0.01 0.02 0.01 0.01 1.1e-01 2.7e-02 1.5e-01 1.2e-01
15 IL gene expression Nubpl 0.36 0.16 2.0e-06 0.21 0.23 0.18 0.18 1.1e-05 2.7e-06 3.7e-05 4.6e-05
16 NAcc gene expression Nubpl 0.07 0.05 6.7e-07 0.06 0.04 0.05 0.06 6.2e-08 1.0e-05 7.1e-07 4.9e-07
17 PL intron excision ratio chr6_69562087_69609481 0.16 0.1 2.7e-13 0.1 0.1 0.1 0.1 1.4e-10 1.9e-11 1.1e-10 6.6e-11
18 BLA gene expression Nubpl 0.2 0.14 6.0e-08 0.13 0.12 0.13 0.13 2.7e-07 6.5e-07 1.3e-07 1.8e-07
19 Brain mRNA stability Nubpl 0.16 0.08 4.6e-14 0.14 0.16 0.15 0.15 3.1e-13 1.3e-14 4.6e-14 3.6e-14
20 NAcc intron excision ratio chr6_69562087_69594180 0.02 0.02 5.0e-03 0.02 0.01 0.01 0.01 3.9e-03 3.7e-02 4.0e-02 2.0e-02
21 BLA mRNA stability Nubpl 0.15 0.1 2.8e-06 0.12 0.1 0.1 0.1 8.3e-07 4.8e-06 3.6e-06 3.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.32.25.12.2-2.3-2.20.52.1-2.0-1.51.40.1-1.51.61.01.51.41.4-1.21.1-1.00.91.1-1.1
Area under the delay curve1.92.03.70.8-0.2-0.21.9-0.70.91.4-1.6-1.91.4-1.2-1.8-1.4-1.4-1.41.4-1.61.8-1.7-1.71.7
BMI with tail0.41.22.1-0.40.00.1-1.30.7-0.8-1.11.41.4-1.21.11.31.21.21.2-1.01.3-1.31.41.2-1.2
BMI without tail2.14.35.81.2-1.8-1.8-1.12.3-2.4-2.42.41.7-2.42.42.12.42.42.3-2.12.2-2.02.21.8-1.9
Body weight1.87.415.83.9-4.0-4.00.93.8-3.6-2.52.70.4-2.93.01.92.92.82.6-1.82.2-2.01.91.9-1.9
Weight adjusted by age0.10.20.5-0.70.60.5-0.7-0.20.1-0.10.20.6-0.20.10.60.20.20.2-0.10.3-0.40.40.5-0.3
Bone surface0.51.04.02.0-1.6-1.61.90.7-0.50.3-0.4-1.50.2-0.0-0.9-0.2-0.2-0.30.6-0.70.8-0.8-0.70.7
Bone volume0.61.15.52.4-2.1-2.11.51.4-1.2-0.40.3-1.0-0.50.6-0.20.50.40.4-0.1-0.00.2-0.2-0.10.1
Breakpoint value in progressive ratio session0.70.84.32.1-1.7-1.71.41.2-1.0-0.20.3-0.9-0.50.5-0.20.50.40.30.20.00.1-0.2-0.20.2
Number of licking bursts0.00.00.0-0.2-0.1-0.1-0.2-0.0-0.00.00.00.1-0.00.1-0.10.1-0.00.00.10.00.00.1-0.20.2
Context. condit. distance diff. score1.72.13.70.5-1.4-1.4-1.31.3-1.4-1.91.21.2-1.31.61.51.41.31.6-1.91.2-1.51.41.8-1.8
Locomotion velocity, session 10.20.30.70.10.10.10.6-0.30.30.7-0.6-0.60.4-0.4-0.5-0.4-0.5-0.50.8-0.50.6-0.5-0.70.8
Locomotion distance, session 10.50.63.1-1.81.51.5-1.1-1.11.00.4-0.50.60.5-0.5-0.0-0.5-0.5-0.40.2-0.20.10.0-0.10.1
Locomotion velocity, session 22.32.74.0-1.51.51.50.4-2.01.91.9-1.9-0.91.8-1.8-1.6-1.8-1.9-1.81.7-1.71.6-1.5-1.61.6
Locomotion distance, session 21.72.46.5-2.42.62.6-0.6-2.22.01.5-1.30.01.5-1.6-1.0-1.5-1.4-1.41.2-1.00.9-0.9-1.21.1
Locomotion velocity, session 30.91.02.2-1.51.11.1-0.4-1.51.30.9-1.3-0.21.2-1.0-0.7-1.2-1.2-1.00.5-1.00.7-0.7-0.50.5
Locomotion distance, session 30.70.82.2-0.7-0.2-0.2-1.50.3-0.5-1.10.71.2-0.70.81.00.70.60.8-1.20.8-1.01.01.2-1.1
Stereotopy head waving bouts, day 31.72.03.4-1.41.51.50.2-1.81.81.4-1.7-0.71.7-1.6-1.3-1.7-1.6-1.51.1-1.51.3-1.3-1.11.1
Stereotopy head waving duration, day 32.02.33.1-1.11.41.40.6-1.81.81.6-1.8-1.01.7-1.7-1.5-1.7-1.7-1.61.4-1.61.6-1.5-1.61.5
Locomotion velocity, session 73.94.29.7-1.30.20.2-3.10.8-1.1-2.32.02.8-1.81.82.51.81.82.0-2.52.2-2.42.42.5-2.4
Locomotion distance, session 73.74.77.2-0.5-0.4-0.4-2.61.4-1.7-2.32.42.7-2.22.22.72.22.22.2-2.22.4-2.62.62.6-2.5
Stereotopy head waving bouts, day 70.70.81.20.20.20.21.0-0.60.70.9-1.0-1.11.0-0.9-1.1-1.0-0.9-0.90.8-1.11.1-1.1-1.01.0
Stereotopy head waving duration, day 71.41.72.5-0.50.80.80.8-1.31.41.2-1.5-1.21.5-1.4-1.6-1.5-1.4-1.40.9-1.51.6-1.4-1.51.4
Locomotion velocity, session 80.20.30.5-0.40.50.50.2-0.60.60.5-0.7-0.40.6-0.6-0.4-0.6-0.6-0.60.3-0.50.4-0.6-0.40.3
Locomotion distance, session 80.20.31.2-0.6-0.1-0.1-1.1-0.0-0.1-0.70.10.7-0.20.40.50.20.20.4-0.90.3-0.50.50.7-0.7
Degree of sensitization distance0.30.30.40.5-0.4-0.4-0.10.7-0.6-0.40.70.3-0.60.60.60.60.60.5-0.30.6-0.50.50.4-0.4
Degree of sensitization stereotypy0.30.31.00.8-0.4-0.41.00.10.10.4-0.4-0.90.3-0.3-0.6-0.4-0.3-0.40.4-0.50.6-0.7-0.60.6
Conditioned locomotion1.01.11.8-0.80.80.70.2-1.21.21.1-1.3-0.81.3-1.1-1.2-1.2-1.3-1.10.9-1.21.2-1.1-1.01.0
Cocaine response after cond. corrected0.50.51.1-0.1-0.3-0.3-0.90.5-0.5-0.80.70.8-0.60.70.80.60.60.7-0.90.7-0.90.81.0-1.0
Cocaine response after cond. not corrected1.41.62.30.2-0.6-0.5-1.11.1-1.1-1.41.41.3-1.31.31.41.31.31.3-1.31.4-1.51.41.5-1.5
Cocaine response before conditioning0.50.61.20.10.00.1-0.50.7-0.7-0.61.10.8-1.00.70.91.01.00.8-0.51.1-1.00.90.7-0.6
Saline control response0.40.52.31.5-1.4-1.40.91.0-0.9-0.30.4-0.5-0.50.50.00.50.40.3-0.00.20.00.0-0.20.2
Bone: connectivity density2.94.510.33.1-3.2-3.20.63.0-2.8-2.22.00.2-2.12.31.52.12.12.1-1.71.6-1.51.31.6-1.6
Bone: cortical apparent density1.21.52.8-0.70.40.4-1.60.5-0.7-1.21.41.7-1.21.01.61.21.21.2-1.31.4-1.51.51.5-1.4
Bone: cortical area1.01.55.42.3-1.9-1.82.30.7-0.40.5-0.8-2.00.5-0.3-1.3-0.5-0.6-0.50.8-1.11.1-1.2-0.80.8
Bone: cortical porosity0.70.81.40.30.00.01.1-0.50.70.7-1.1-1.21.0-0.9-1.2-1.0-0.9-0.90.6-1.11.1-1.1-0.80.8
Bone: cortical porosity1.01.11.90.30.20.21.2-0.70.91.0-1.3-1.41.2-1.1-1.4-1.2-1.1-1.10.8-1.21.2-1.3-1.01.0
Bone: cortical thickness0.20.41.31.1-1.1-1.10.50.9-0.8-0.50.4-0.2-0.50.60.20.50.50.5-0.40.2-0.40.20.6-0.5
Bone: cortical thickness0.10.10.5-0.10.0-0.0-0.40.1-0.1-0.50.20.3-0.20.20.20.20.20.3-0.70.3-0.50.20.6-0.7
Bone: cortical tissue density1.11.52.8-0.80.40.4-1.60.5-0.6-1.11.41.7-1.11.01.61.11.21.1-1.21.4-1.51.41.4-1.4
Condit. Reinf. active minus inactive responses0.91.03.71.9-1.6-1.61.90.7-0.60.5-0.3-1.40.10.0-0.8-0.1-0.2-0.31.0-0.60.7-0.7-0.90.8
Condit. Reinf. active-inactive response ratio0.20.20.70.8-0.8-0.80.70.4-0.30.10.1-0.4-0.10.1-0.40.10.0-0.00.3-0.10.3-0.1-0.50.4
Condit. Reinf. active responses1.31.55.92.1-1.6-1.62.40.5-0.30.9-0.8-1.90.5-0.4-1.2-0.5-0.6-0.71.4-1.01.1-1.2-1.31.2
Condit. Reinf. inactive responses0.40.51.50.8-0.4-0.41.2-0.10.20.8-0.7-1.10.5-0.5-0.7-0.5-0.6-0.60.9-0.70.7-0.8-0.60.7
Incentive salience index mean1.31.65.81.9-1.4-1.42.40.3-0.11.0-0.9-2.00.6-0.5-1.4-0.6-0.8-0.81.5-1.11.3-1.3-1.41.3
Condit. Reinf. lever presses0.40.61.50.7-0.3-0.31.2-0.20.30.8-0.7-1.10.6-0.6-1.0-0.6-0.6-0.71.0-0.80.9-0.8-1.00.9
Condit. Reinf. active minus inactive responses0.00.00.1-0.30.20.1-0.1-0.20.10.1-0.10.10.1-0.10.0-0.1-0.1-0.10.1-0.1-0.1-0.00.1-0.1
Condit. Reinf. active-inactive response ratio0.20.20.5-0.60.70.7-0.0-0.70.60.4-0.5-0.20.6-0.6-0.4-0.5-0.5-0.50.3-0.40.3-0.4-0.30.3
Condit. Reinf. active responses0.10.10.2-0.40.40.40.0-0.40.30.4-0.3-0.00.3-0.3-0.1-0.3-0.3-0.30.4-0.20.1-0.2-0.00.1
Condit. Reinf. inactive responses0.10.20.40.1-0.2-0.1-0.30.4-0.4-0.20.50.4-0.50.40.70.50.50.4-0.00.5-0.60.50.5-0.5
Condit. Reinf. lever presses0.30.31.71.0-0.5-0.51.30.2-0.10.6-0.3-0.90.2-0.3-0.4-0.2-0.2-0.40.9-0.40.4-0.6-0.60.7
Condit. Reinf. lever reinforcers received0.20.30.90.5-0.3-0.31.0-0.10.20.7-0.6-0.80.5-0.4-0.5-0.5-0.5-0.50.8-0.60.5-0.6-0.50.5
Conditioned reinforcement - actives1.81.84.20.8-0.2-0.22.0-0.60.81.4-1.5-1.91.2-1.2-1.5-1.3-1.3-1.31.6-1.51.5-1.6-1.51.5
Conditioned reinforcement - inactives0.30.31.51.2-0.9-0.91.10.5-0.40.1-0.0-0.8-0.00.1-0.20.0-0.0-0.10.4-0.20.3-0.3-0.20.2
Conditioned locomotion0.30.40.5-0.00.20.20.7-0.50.50.7-0.7-0.70.6-0.6-0.5-0.6-0.7-0.70.7-0.70.6-0.7-0.60.6
Patch foraging indifference point 0 sec1.11.76.12.0-1.2-1.32.50.3-0.01.0-0.9-2.10.7-0.6-1.4-0.7-0.8-0.91.4-1.21.4-1.4-1.61.6
Patch foraging indifference point AUC1.51.74.11.0-0.6-0.52.0-0.50.71.1-1.6-2.01.3-1.1-1.5-1.3-1.3-1.21.1-1.61.5-1.7-1.21.2
Delay disc. indifference point, 0s delay0.50.61.60.9-0.7-0.71.2-0.00.10.5-0.7-1.10.6-0.4-1.0-0.6-0.6-0.60.7-0.80.9-0.8-0.80.6
Delay disc. indifference point, 16s delay2.22.23.40.20.40.41.7-1.01.21.6-1.6-1.81.5-1.5-1.8-1.5-1.6-1.61.6-1.71.8-1.7-1.71.8
Delay disc. indifference point, 2s delay0.30.31.00.9-0.7-0.71.00.2-0.10.3-0.4-0.90.3-0.2-0.6-0.3-0.3-0.30.4-0.60.5-0.6-0.40.4
Delay disc. indifference point, 24s delay3.53.36.61.0-0.1-0.12.6-0.81.12.0-1.8-2.41.7-1.6-2.2-1.7-1.7-1.82.1-2.02.2-2.1-2.32.3
Delay disc. indifference point, 4s delay0.20.20.5-0.40.20.20.1-0.60.50.3-0.7-0.30.6-0.5-0.7-0.6-0.6-0.50.2-0.60.6-0.5-0.50.3
Delay disc. indifference point, 8s delay0.30.30.80.7-0.5-0.50.90.1-0.00.3-0.4-0.80.3-0.2-0.7-0.3-0.3-0.30.4-0.50.6-0.5-0.60.6
Indifference point function ln k0.30.40.8-0.1-0.1-0.1-0.80.5-0.6-0.60.90.8-0.80.70.70.70.70.7-0.40.8-0.70.80.5-0.5
Indifference point function log k0.30.40.8-0.1-0.1-0.1-0.80.5-0.6-0.60.90.8-0.80.70.70.70.70.7-0.40.8-0.70.80.5-0.5
Patch foraging total patch changes 0 sec1.32.17.12.0-1.2-1.22.70.20.11.2-1.1-2.30.8-0.8-1.6-0.9-1.0-1.11.6-1.41.6-1.6-1.71.7
Patch foraging total patch changes 12 sec1.51.96.71.8-1.0-1.02.60.10.21.2-1.2-2.20.9-0.9-1.6-0.9-1.0-1.11.4-1.31.6-1.6-1.61.6
Patch foraging total patch changes 18 sec0.40.51.70.7-0.2-0.21.3-0.10.30.8-0.6-1.00.5-0.6-0.8-0.5-0.5-0.60.8-0.60.8-0.8-0.80.8
Patch foraging total patch changes 24 sec0.81.02.50.60.10.11.6-0.40.61.2-1.0-1.40.9-0.9-1.2-0.9-0.9-1.01.2-1.01.1-1.2-1.21.2
Patch foraging total patch changes 6 sec1.01.56.02.2-1.6-1.62.50.5-0.30.7-0.8-2.00.5-0.4-1.2-0.5-0.6-0.71.0-1.11.2-1.2-1.21.2
Patch foraging time to switch 0 sec8.112.528.8-2.50.90.9-5.41.3-1.9-3.63.85.1-3.33.04.03.33.43.4-4.04.1-4.04.33.8-3.7
Patch foraging water rate 0 sec2.84.59.41.3-0.3-0.33.1-0.91.32.2-2.4-2.92.0-1.9-2.5-2.0-2.1-2.12.4-2.42.4-2.6-2.32.2
Patch foraging water rate 12 sec0.40.62.91.7-1.3-1.41.21.1-0.9-0.20.4-0.7-0.50.50.10.50.40.30.10.1-0.1-0.00.1-0.2
Patch foraging water rate 18 sec0.60.83.41.3-0.9-0.91.80.20.00.7-0.7-1.50.5-0.5-1.0-0.5-0.6-0.60.9-0.90.9-1.0-0.80.8
Patch foraging water rate 24 sec0.50.72.71.6-1.6-1.71.30.7-0.6-0.1-0.3-1.10.10.2-0.7-0.1-0.1-0.00.0-0.50.6-0.5-0.50.4
Patch foraging water rate 6 sec2.33.49.51.9-1.0-1.03.1-0.30.61.6-1.8-2.81.4-1.3-2.2-1.4-1.5-1.61.9-2.02.2-2.2-2.12.1
Seeking ratio, delayed vs. immediate footshock0.30.41.1-1.10.90.8-0.5-0.90.80.3-0.70.10.7-0.6-0.3-0.6-0.6-0.50.1-0.50.4-0.3-0.30.2
Distance traveled before self-admin0.00.00.10.1-0.0-0.00.3-0.10.10.2-0.2-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.20.2-0.2-0.20.1
Distance traveled after self-admin0.10.10.5-0.70.60.6-0.5-0.40.30.10.00.30.1-0.20.0-0.1-0.1-0.10.00.0-0.00.1-0.00.0
Extensor digitorum longus weight2.18.115.63.9-3.9-3.90.83.9-3.7-2.82.90.5-3.13.12.43.03.02.8-1.92.4-2.32.02.1-2.1
Bone: elastic displacement1.72.03.00.3-0.7-0.7-1.21.2-1.3-1.51.61.4-1.51.51.71.51.51.5-1.31.5-1.71.51.7-1.7
Bone: elastic work3.14.05.11.1-1.6-1.6-1.12.1-2.2-2.22.31.6-2.22.22.12.22.22.1-1.92.1-2.32.02.2-2.2
Bone: endosteal estimation2.65.68.90.7-0.00.02.7-1.51.72.4-2.7-2.92.4-2.2-2.9-2.4-2.5-2.42.4-2.83.0-2.8-2.92.8
Bone: endosteal perimeter3.16.411.51.3-0.5-0.53.3-1.21.52.5-2.8-3.42.5-2.2-3.3-2.4-2.5-2.52.7-3.03.1-3.0-2.92.9
Epididymis fat weight0.20.50.9-0.40.20.2-0.90.3-0.4-0.60.91.0-0.70.60.70.70.70.7-0.70.8-0.80.80.8-0.8
Delta time in closed arm before/after self-admin0.10.10.60.7-0.6-0.60.70.3-0.20.1-0.1-0.60.1-0.0-0.3-0.1-0.1-0.10.2-0.20.2-0.3-0.20.2
Delta time in open arm before/after self-admin0.20.20.30.4-0.5-0.50.10.5-0.5-0.40.50.2-0.50.50.50.50.50.5-0.30.4-0.40.40.4-0.4
Diff in mean of infusions in LGA sessions0.80.91.6-1.11.21.20.0-1.21.21.1-0.9-0.41.0-1.1-0.9-1.0-1.0-1.00.9-0.80.8-0.8-0.80.8
Delay discount exponential model param1.61.72.9-0.60.10.1-1.60.7-0.8-1.31.41.7-1.31.21.71.31.31.3-1.31.5-1.61.51.6-1.5
Extinction: sum of active levers before priming3.93.96.92.4-2.6-2.60.12.6-2.5-2.12.00.7-2.12.21.62.12.12.0-1.71.7-1.61.51.5-1.5
Active lever presses in extinction session 62.72.66.42.5-2.5-2.50.72.3-2.2-1.51.50.0-1.71.71.01.71.61.5-1.01.2-1.01.00.9-0.9
Bone: final force0.10.20.50.4-0.7-0.7-0.30.4-0.4-0.60.20.1-0.20.40.10.30.30.4-0.70.1-0.40.20.7-0.7
Bone: final moment0.10.10.50.4-0.7-0.7-0.10.3-0.3-0.5-0.0-0.1-0.10.3-0.00.10.10.3-0.5-0.0-0.20.00.6-0.6
Food consumed during 24 hour testing period0.40.41.51.2-1.0-1.01.20.4-0.20.4-0.4-1.00.2-0.1-0.6-0.2-0.3-0.30.7-0.50.6-0.5-0.70.7
Glucose0.81.34.52.1-2.0-2.11.01.6-1.5-0.70.9-0.4-1.01.10.41.00.90.8-0.20.5-0.50.40.5-0.5
Heart weight0.30.41.91.4-0.9-0.91.30.6-0.50.20.1-0.8-0.20.1-0.40.10.1-0.10.5-0.10.4-0.3-0.60.6
Delay discount hyperbolic model param1.41.42.5-0.60.20.2-1.50.6-0.7-1.21.31.6-1.21.01.61.21.21.2-1.21.4-1.51.41.5-1.4
Intermittent access intake day 1-15 change1.21.21.71.0-1.2-1.2-0.21.3-1.3-1.31.20.5-1.21.21.11.21.21.1-1.21.1-0.90.91.0-1.0
Intermittent access intake escalation1.71.72.61.3-1.5-1.5-0.11.6-1.6-1.51.40.6-1.41.41.21.41.41.3-1.41.2-1.11.11.1-1.1
Intermittent access intake escalation 23.63.65.01.3-1.8-1.8-0.92.1-2.1-2.22.11.4-2.12.12.02.12.12.1-2.02.0-1.81.91.8-1.8
Intermitt. access day 1 inactive lever presses1.71.83.30.60.00.01.8-0.70.91.5-1.5-1.81.3-1.3-1.5-1.3-1.4-1.41.6-1.51.4-1.6-1.41.4
Intermitt. access day 15 inactive lever presses2.42.65.00.60.20.22.2-1.01.21.8-1.7-2.11.6-1.6-1.7-1.6-1.6-1.71.9-1.81.8-1.9-1.81.8
Intermitt. access escalation Index1.41.21.70.8-1.1-1.1-0.51.3-1.3-1.21.20.8-1.21.31.11.21.21.2-1.01.1-1.11.11.1-1.1
Intermittent access day 1 total infusions0.40.41.60.9-0.6-0.61.30.10.00.5-0.5-1.10.4-0.4-0.6-0.4-0.5-0.50.8-0.70.6-0.7-0.60.6
Intermittent access day 15 total infusions0.80.92.61.6-1.6-1.60.71.3-1.2-0.80.8-0.2-0.80.90.60.80.80.7-0.60.6-0.50.40.5-0.5
Intermittent access terminal intake (last 3 days)0.40.51.91.4-1.3-1.30.81.0-0.9-0.50.5-0.3-0.50.60.30.50.50.5-0.30.3-0.20.10.2-0.2
Intermittent access total infusions0.60.61.61.2-1.3-1.30.41.1-1.0-0.70.7-0.0-0.80.80.60.80.70.7-0.50.5-0.50.40.5-0.5
Intermittent access day 1 locomotion0.80.92.40.8-0.3-0.31.5-0.30.40.9-0.9-1.40.8-0.8-1.0-0.8-0.9-0.91.1-1.01.0-1.1-1.01.0
Intermittent access day 15 total locomotion0.60.71.81.3-1.4-1.40.41.1-1.1-0.80.6-0.1-0.80.80.70.80.70.7-0.50.5-0.50.40.6-0.6
Intermittent access total locomotion0.50.61.51.1-1.2-1.20.21.1-1.0-0.80.60.1-0.80.80.70.80.70.7-0.50.5-0.60.50.6-0.6
Intermittent access standard deviation0.20.20.91.0-0.9-0.90.70.7-0.6-0.40.4-0.3-0.40.40.20.40.40.3-0.30.2-0.20.10.2-0.2
Left kidney weight1.02.73.81.4-1.7-1.7-0.41.9-1.9-1.81.81.0-1.81.81.61.81.81.8-1.61.7-1.61.51.6-1.7
Right kidney weight1.13.24.21.2-1.5-1.5-0.72.0-2.0-2.02.11.4-2.02.01.82.02.01.9-1.81.9-1.81.81.8-1.8
Cocaine induced anxiety1.01.11.50.10.40.41.2-0.80.91.2-1.2-1.21.1-1.1-1.2-1.1-1.1-1.11.2-1.21.2-1.2-1.21.2
Post-drug Anxiety1.01.11.5-0.10.50.51.1-0.91.01.2-1.1-1.11.1-1.1-1.2-1.1-1.1-1.11.2-1.11.2-1.2-1.21.2
Baseline Anxiety0.40.51.9-1.00.60.6-1.4-0.1-0.0-0.50.51.1-0.40.40.70.40.40.5-0.70.6-0.70.80.7-0.7
Tail length0.72.15.82.3-2.3-2.40.62.1-2.0-1.41.2-0.0-1.51.50.91.51.41.3-1.01.0-0.90.80.8-0.8
Length with tail1.76.121.24.6-4.4-4.52.03.6-3.3-1.91.8-0.8-2.22.41.12.22.01.9-1.11.3-1.20.91.2-1.2
Length without tail1.02.18.32.9-2.7-2.71.52.1-1.9-0.90.9-0.7-1.21.30.61.21.11.0-0.40.6-0.70.40.8-0.8
Times rat made contact with spout0.60.61.4-0.4-0.2-0.2-1.20.4-0.6-0.90.81.1-0.70.80.90.80.70.8-0.90.8-0.91.00.9-0.9
Lifetime Intake0.40.41.31.1-1.1-1.10.30.9-0.9-0.60.6-0.0-0.60.70.50.60.60.6-0.30.4-0.40.40.4-0.4
Liver weight, left0.50.82.31.1-1.5-1.50.01.1-1.1-1.10.70.1-0.81.00.60.80.70.8-1.00.5-0.50.60.7-0.8
Liver weight, right0.81.32.41.0-1.5-1.6-0.51.3-1.3-1.41.10.6-1.11.31.11.11.11.2-1.20.9-1.01.01.2-1.2
Locomotor activity2.03.316.84.1-3.6-3.52.82.5-2.1-0.60.7-1.7-1.01.10.01.00.80.70.20.10.1-0.3-0.10.1
Locomotor testing distance2.13.513.83.7-3.4-3.31.92.8-2.5-1.31.4-0.8-1.61.70.91.61.51.3-0.40.9-0.70.50.5-0.5
Locomotor testing rearing3.75.811.03.2-3.2-3.20.43.3-3.2-2.42.60.6-2.72.62.02.72.62.4-1.72.2-1.81.81.5-1.5
Locomotion in novel chamber0.70.93.8-1.50.80.8-1.9-0.30.0-0.90.61.5-0.40.50.90.40.50.7-1.20.8-0.91.01.0-1.2
Locomotion in novel chamber post-restriction2.22.73.7-1.11.31.40.8-1.81.81.9-1.8-1.21.8-1.8-1.6-1.8-1.8-1.81.8-1.71.7-1.6-1.71.7
Fecal boli incidents, locomotor time 11.61.83.21.6-1.5-1.50.11.8-1.7-1.31.50.5-1.51.51.11.51.51.4-1.01.3-1.31.11.1-1.1
Change in fecal boli incidents, locomotor task0.30.20.40.3-0.6-0.6-0.30.5-0.5-0.70.40.3-0.50.60.50.50.40.5-0.60.4-0.50.50.6-0.6
Time >=10cm from walls, locomotor time 10.20.20.90.9-0.8-0.80.80.4-0.3-0.1-0.1-0.60.00.1-0.3-0.0-0.0-0.0-0.0-0.20.2-0.30.0-0.1
Bouts of movement, locomotor time 11.41.53.90.80.10.12.0-0.50.71.4-1.3-1.71.1-1.1-1.5-1.1-1.1-1.21.4-1.31.3-1.5-1.31.2
Total resting periods, locomotor time 11.71.94.30.70.20.22.1-0.70.91.6-1.4-1.91.3-1.3-1.6-1.3-1.3-1.41.7-1.51.5-1.6-1.51.5
Rest time, locomotor task time 14.34.87.20.40.90.92.7-1.51.82.6-2.2-2.62.1-2.2-2.5-2.2-2.2-2.32.7-2.32.3-2.5-2.52.6
Distance moved, locomotor task time 12.02.23.50.1-0.9-0.9-1.61.2-1.3-1.91.51.6-1.51.61.61.51.51.6-1.91.5-1.51.61.7-1.7
Vertical activity count, locomotor time 12.42.53.50.3-1.2-1.2-1.41.4-1.5-1.91.61.6-1.61.71.81.71.61.7-1.71.6-1.71.71.7-1.8
Time >=10cm from walls, locomotor time 20.70.72.51.6-1.5-1.50.61.2-1.1-0.80.8-0.3-0.70.80.20.70.70.7-0.60.4-0.40.30.4-0.6
Bouts of movement, locomotor time 20.50.51.00.00.20.20.7-0.60.60.9-0.8-0.80.7-0.7-0.7-0.7-0.8-0.81.0-0.80.8-0.8-0.80.7
Total resting periods, locomotor time 20.40.40.7-0.20.50.50.5-0.60.60.8-0.7-0.60.7-0.7-0.5-0.7-0.7-0.70.8-0.70.7-0.7-0.60.6
Rest time, locomotor task time 20.00.00.2-0.10.40.40.2-0.20.20.2-0.0-0.10.1-0.2-0.1-0.1-0.1-0.20.2-0.10.1-0.20.00.2
Distance moved, locomotor task time 20.10.10.50.6-0.7-0.70.40.2-0.2-0.0-0.0-0.40.10.1-0.4-0.1-0.1-0.1-0.0-0.20.4-0.2-0.50.2
Vertical activity count, locomotor time 20.10.10.1-0.2-0.0-0.0-0.0-0.30.20.2-0.3-0.10.3-0.2-0.2-0.2-0.3-0.30.2-0.30.3-0.2-0.40.3
Light reinforcement 10.71.32.00.9-1.0-1.1-0.31.4-1.4-1.11.40.8-1.41.31.01.41.41.2-0.91.3-1.11.20.8-0.8
Light reinforcement 22.33.14.3-1.11.71.70.9-1.91.92.1-1.9-1.21.8-1.9-1.9-1.8-1.8-1.91.9-1.61.8-1.6-2.02.0
Bone: marrow area2.65.79.00.7-0.00.02.7-1.51.72.4-2.7-3.02.4-2.2-2.9-2.4-2.5-2.42.4-2.83.0-2.8-2.92.8
Bone: maximum diameter4.17.615.21.9-0.9-0.83.9-1.11.52.8-3.0-3.92.5-2.3-3.5-2.5-2.6-2.63.0-3.23.3-3.3-3.13.1
Bone: maximum force0.10.20.50.7-0.7-0.70.60.1-0.00.0-0.5-0.70.4-0.1-0.6-0.3-0.3-0.2-0.1-0.60.4-0.5-0.00.0
Bone: maximum moment0.20.30.70.7-0.7-0.70.70.00.10.1-0.7-0.80.5-0.2-0.7-0.4-0.5-0.30.0-0.70.5-0.7-0.10.1
Mean time between licks in bursts0.00.00.00.00.10.10.1-0.00.10.0-0.1-0.10.1-0.10.0-0.1-0.1-0.1-0.1-0.10.0-0.10.1-0.1
Mean num. licks in bursts0.30.40.60.3-0.5-0.5-0.30.6-0.6-0.80.60.5-0.60.60.70.60.70.7-0.70.6-0.60.60.8-0.8
Cd content in liver1.81.92.91.3-1.6-1.6-0.31.7-1.7-1.61.50.7-1.51.51.21.51.51.5-1.51.2-1.21.21.3-1.3
Co content in liver1.01.12.41.1-1.5-1.5-0.11.3-1.3-1.11.10.5-1.11.20.81.11.01.1-0.90.9-0.90.91.0-1.0
Cu content in liver0.40.51.4-0.60.10.1-1.20.2-0.3-0.80.61.0-0.60.60.80.60.60.7-0.90.7-0.80.81.0-1.0
Fe content in liver0.20.30.8-0.80.80.7-0.9-0.20.1-0.30.50.8-0.30.10.50.30.30.3-0.40.5-0.50.50.4-0.4
K content in liver3.93.89.7-3.12.92.8-1.0-2.82.61.6-2.0-0.12.1-2.1-1.4-2.1-2.0-1.80.9-1.51.3-1.2-1.21.2
Mg content in liver2.52.510.7-3.32.82.8-1.7-2.42.10.9-1.20.71.4-1.4-0.6-1.4-1.3-1.10.2-0.80.6-0.4-0.50.5
Mn content in liver5.76.49.1-1.72.12.01.1-2.92.92.6-3.0-1.93.0-2.8-2.7-2.9-2.9-2.82.1-2.82.6-2.6-2.42.4
Na content in liver0.70.83.5-1.91.61.6-1.7-0.80.7-0.20.21.20.0-0.20.5-0.00.10.1-0.70.4-0.50.50.5-0.5
Rb content in liver1.51.86.3-2.52.22.2-1.0-2.01.81.0-1.20.31.3-1.3-0.7-1.3-1.2-1.10.5-0.80.6-0.6-0.50.5
Se content in liver1.72.09.9-3.13.03.0-2.1-1.81.50.4-0.21.40.6-0.80.3-0.6-0.4-0.4-0.20.1-0.20.30.1-0.1
Sr content in liver0.80.71.00.5-0.6-0.6-0.40.9-0.9-0.91.00.6-0.90.90.90.90.90.9-0.90.9-0.90.80.8-0.8
Zn content in liver0.00.00.2-0.50.40.4-0.3-0.30.30.1-0.10.10.2-0.20.0-0.2-0.2-0.10.0-0.10.0-0.00.0-0.0
Bone: minimum diameter0.81.54.41.6-1.2-1.22.10.10.20.8-1.1-1.90.9-0.7-1.6-0.9-0.9-0.90.9-1.31.5-1.5-1.11.1
Time in familiar zone, hab. session 11.41.31.90.2-0.3-0.3-1.01.0-1.0-1.31.31.1-1.21.11.31.21.31.2-1.41.3-1.31.21.4-1.3
Time in novel zone, hab. session 10.90.81.30.3-0.1-0.11.1-0.50.61.0-1.0-1.10.9-0.8-1.1-0.9-1.0-0.91.0-1.11.1-1.0-1.11.1
Total zone transitions, hab. session 12.23.15.4-2.12.22.2-0.1-2.32.21.9-1.9-0.61.9-1.9-1.4-1.9-1.9-1.81.5-1.61.4-1.4-1.41.4
Total locomotion distance, hab. session 11.11.66.7-2.62.42.4-1.4-1.81.60.9-0.80.71.0-1.1-0.3-0.9-0.9-0.80.5-0.40.3-0.2-0.40.3
Locomotion velocity, hab. session 11.92.76.8-2.62.62.6-0.7-2.32.21.6-1.50.01.6-1.7-1.0-1.6-1.6-1.51.2-1.11.0-0.9-1.11.1
Time in familiar zone, hab. session 21.71.82.8-0.40.20.2-1.50.8-0.9-1.31.61.7-1.41.21.71.41.41.3-1.31.6-1.61.51.6-1.6
Time in novel zone, hab. session 22.32.24.91.0-0.5-0.52.2-0.60.81.5-1.6-2.11.3-1.2-1.8-1.3-1.4-1.41.7-1.71.8-1.7-1.81.8
Total zone transitions, hab. session 25.06.59.9-2.52.82.80.5-3.13.12.9-2.8-1.32.8-2.8-2.4-2.8-2.8-2.72.5-2.42.3-2.2-2.52.4
Total locomotion distance, hab. session 23.95.28.3-2.42.92.90.3-2.92.82.6-2.3-1.02.4-2.5-1.9-2.4-2.3-2.42.3-2.01.8-1.8-2.02.0
Locomotion velocity, hab. session 24.45.99.5-2.63.03.00.3-3.13.02.7-2.5-1.02.6-2.7-2.1-2.6-2.6-2.52.4-2.22.0-2.0-2.12.1
Novel to familiar place preference ratio0.60.61.40.6-0.3-0.31.2-0.30.40.8-0.9-1.20.8-0.7-0.9-0.8-0.8-0.80.9-1.00.9-1.0-0.70.8
Novelty place preference1.31.33.41.0-0.6-0.61.8-0.30.51.1-1.2-1.71.0-0.9-1.3-1.0-1.1-1.11.3-1.31.3-1.4-1.11.2
Time in novel zone, NPP test0.90.92.81.1-0.7-0.71.7-0.10.30.9-1.0-1.50.8-0.7-1.0-0.8-0.8-0.81.1-1.11.0-1.2-0.90.9
Total zone transitions, NPP test1.62.23.3-1.51.71.70.2-1.81.81.6-1.5-0.71.6-1.6-1.4-1.6-1.5-1.51.4-1.31.4-1.2-1.61.6
Total locomotion distance, NPP test1.92.64.2-1.81.81.80.1-2.02.01.8-1.7-0.61.7-1.7-1.5-1.7-1.7-1.71.5-1.41.4-1.3-1.61.6
Locomotion velocity, NPP test1.31.93.2-1.71.71.7-0.1-1.81.71.4-1.4-0.41.4-1.4-1.2-1.4-1.4-1.41.2-1.21.2-1.0-1.41.4
Intraocular pressure1.21.72.91.4-1.7-1.6-0.01.6-1.6-1.31.30.5-1.41.41.21.41.31.3-1.01.1-1.21.01.2-1.2
Delta distance traveled before/after self-admin0.30.41.1-1.01.11.1-0.4-0.80.80.6-0.40.10.5-0.6-0.3-0.5-0.5-0.50.4-0.30.3-0.3-0.50.5
Delta ambulatory time before/after self-admin0.40.41.4-1.21.21.2-0.5-0.90.90.6-0.40.20.6-0.6-0.3-0.6-0.5-0.50.4-0.30.3-0.3-0.40.5
Parametrial fat weight2.95.78.31.3-2.0-1.9-1.42.5-2.6-2.92.61.9-2.62.62.52.62.62.6-2.72.5-2.42.42.5-2.5
Pavlov. Cond. lever latency1.21.52.70.3-0.9-0.9-1.11.1-1.2-1.61.31.2-1.21.41.21.21.31.4-1.61.2-1.11.31.3-1.2
Pavlov. Cond. magazine entry latency1.11.44.6-1.92.12.1-0.5-1.71.51.3-0.80.11.0-1.2-0.5-1.0-1.0-1.11.1-0.60.5-0.5-0.60.5
Pavlov. Cond. change in total contacts1.81.93.9-0.71.21.21.0-1.41.51.9-1.4-1.11.4-1.6-1.3-1.4-1.5-1.62.0-1.31.2-1.3-1.41.3
Pavlov. Cond. index score1.51.93.5-1.51.91.90.3-1.71.71.8-1.3-0.61.4-1.6-1.0-1.4-1.4-1.51.7-1.11.0-1.1-1.11.1
Pavlov. Cond. latency score1.62.13.6-1.41.81.80.5-1.71.71.9-1.4-0.71.4-1.6-1.1-1.5-1.5-1.61.8-1.21.1-1.2-1.21.2
Pavlov. Cond. lever contacts0.40.41.2-0.30.70.70.6-0.60.71.0-0.5-0.50.5-0.8-0.5-0.6-0.6-0.81.1-0.50.5-0.6-0.70.6
Pavlov. Cond. magazine entry number2.02.56.22.1-2.5-2.50.12.1-2.0-1.91.30.3-1.51.81.01.51.51.6-1.71.1-1.01.01.1-1.0
Pavlov. Cond. intertrial magazine entries1.61.93.11.3-1.8-1.8-0.41.7-1.7-1.51.40.7-1.51.61.21.51.41.5-1.21.3-1.31.31.2-1.2
Pavlov. Cond. lever-magazine prob. diff.1.31.63.2-1.51.81.80.1-1.61.61.6-1.1-0.41.2-1.4-0.9-1.2-1.2-1.31.5-1.00.8-0.9-1.00.8
Pavlov. Cond. response bias1.41.73.8-1.51.91.90.1-1.71.61.6-1.1-0.41.3-1.5-0.8-1.3-1.3-1.41.5-1.00.8-0.9-0.90.8
Pavlov. Cond. lever latency0.71.04.1-1.50.80.8-2.0-0.2-0.1-0.90.81.6-0.50.60.90.60.60.7-1.30.9-0.91.10.9-0.9
Pavlov. Cond. magazine entry latency0.20.20.5-0.50.70.70.2-0.50.50.6-0.3-0.10.3-0.5-0.2-0.4-0.4-0.50.7-0.20.3-0.3-0.50.5
Pavlov. Cond. change in total contacts0.60.84.31.8-1.0-1.02.10.5-0.30.7-0.5-1.50.2-0.3-0.6-0.2-0.3-0.51.2-0.60.6-0.8-0.80.8
Pavlov. Cond. index score0.50.73.01.2-0.5-0.51.70.10.00.9-0.6-1.30.4-0.5-0.7-0.4-0.5-0.71.3-0.60.7-0.8-0.90.9
Pavlov. Cond. latency score0.70.83.11.0-0.3-0.31.8-0.10.21.1-0.7-1.40.5-0.7-0.8-0.6-0.6-0.81.5-0.80.9-1.0-1.11.1
Pavlov. Cond. lever contacts0.40.52.61.2-0.6-0.51.60.2-0.00.7-0.5-1.20.3-0.4-0.5-0.3-0.3-0.51.0-0.50.6-0.7-0.70.7
Pavlov. Cond. magazine entry number0.60.72.0-0.60.20.2-1.40.3-0.4-1.00.81.2-0.70.70.90.70.80.8-1.20.9-0.91.01.0-1.1
Pavlov. Cond. intertrial magazine entries0.00.00.4-0.4-0.1-0.1-0.6-0.20.1-0.2-0.20.20.20.0-0.1-0.1-0.20.0-0.3-0.20.10.00.0-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.73.21.2-0.5-0.51.80.10.11.0-0.6-1.30.4-0.5-0.7-0.4-0.5-0.71.4-0.70.8-0.9-1.01.0
Pavlov. Cond. response bias0.30.42.00.9-0.4-0.41.40.10.00.7-0.4-1.00.3-0.4-0.4-0.3-0.3-0.51.0-0.50.5-0.6-0.60.6
Time in closed arm before self-admin0.40.52.6-1.61.31.3-1.4-0.80.6-0.0-0.00.90.1-0.20.3-0.1-0.1-0.0-0.30.2-0.20.30.2-0.3
Time in closed arm after self-admin0.50.51.6-1.31.21.2-0.6-1.00.90.5-0.50.20.6-0.7-0.4-0.6-0.6-0.50.2-0.40.3-0.3-0.30.2
Time in open arm before self-admin0.91.01.60.00.30.30.9-0.80.81.1-1.0-1.11.0-1.0-1.3-1.0-1.0-1.01.1-1.11.1-1.1-1.21.1
Time in open arm after self-admin0.80.81.2-0.50.80.80.7-1.01.01.1-0.9-0.71.0-1.0-0.9-1.0-1.0-1.01.1-1.00.9-0.9-0.91.0
Bone: periosteal estimation2.75.611.21.6-0.9-0.93.3-0.91.32.2-2.6-3.32.3-1.9-3.0-2.2-2.3-2.22.3-2.82.9-2.9-2.62.6
Bone: periosteal perimeter1.83.06.81.6-1.1-1.02.6-0.40.71.5-1.9-2.61.5-1.2-2.3-1.5-1.6-1.51.7-2.02.1-2.1-1.81.8
Bone: post-yield work0.70.91.60.20.10.21.2-0.60.80.8-1.2-1.21.1-1.0-1.2-1.1-1.0-1.00.7-1.11.2-1.2-1.00.9
Progressive ratio test 1 active lever presses0.30.31.11.0-0.7-0.71.10.3-0.10.3-0.3-0.90.2-0.2-0.4-0.2-0.2-0.30.4-0.40.4-0.5-0.40.4
Progressive ratio test 1 breakpoint0.50.51.50.7-0.3-0.31.2-0.20.30.7-0.7-1.10.6-0.6-0.8-0.6-0.6-0.70.8-0.80.8-0.9-0.70.7
Progressive ratio test 1 inactive lever presses1.11.24.01.3-0.7-0.72.0-0.00.21.0-1.0-1.70.8-0.7-1.1-0.8-0.8-0.91.3-1.11.1-1.3-1.11.1
Progressive ratio test 2 active lever presses0.00.00.2-0.40.30.3-0.2-0.30.20.1-0.20.10.2-0.10.0-0.2-0.1-0.10.0-0.10.0-0.00.0-0.0
Progressive ratio test 2 breakpoint0.00.00.2-0.50.30.3-0.4-0.30.2-0.0-0.10.30.1-0.10.2-0.1-0.1-0.0-0.10.0-0.10.10.1-0.1
Progressive ratio test 2 inactive lever presses0.40.41.50.8-0.4-0.41.2-0.00.10.6-0.6-1.10.5-0.4-0.6-0.5-0.5-0.60.7-0.70.7-0.8-0.70.7
Incentive Sensitization - Responses1.01.04.3-2.01.31.3-2.1-0.60.3-0.60.61.7-0.30.31.00.40.40.5-0.90.8-0.81.00.8-0.8
Incentive Sensitization - Breakpoint0.91.03.9-1.81.21.2-2.0-0.50.2-0.60.61.6-0.40.31.00.40.50.5-0.90.8-0.81.00.9-0.9
Sum of active levers in priming session hrs 5-60.50.51.71.3-1.2-1.20.51.1-1.0-0.50.6-0.2-0.70.70.20.70.60.6-0.20.5-0.30.30.1-0.2
Progressive ratio1.51.72.9-1.51.61.60.1-1.71.71.3-1.3-0.61.5-1.5-1.2-1.5-1.4-1.41.0-1.21.1-1.1-1.01.0
Food seeking constrained by brief footshock0.40.50.9-0.20.00.00.5-0.60.60.7-0.9-0.70.8-0.6-0.8-0.8-0.8-0.70.7-0.90.8-0.7-0.70.6
Seeking ratio, punishment vs. effort0.40.51.41.0-1.2-1.20.21.0-1.0-0.70.60.1-0.80.80.60.80.70.7-0.40.6-0.50.50.5-0.5
Retroperitoneal fat weight2.58.411.80.4-1.2-1.2-2.52.5-2.7-3.23.43.0-3.13.03.13.13.23.1-3.23.3-3.23.23.2-3.2
Reaction time number correct0.71.01.50.2-0.5-0.5-0.90.9-1.0-1.21.21.0-1.11.11.01.11.11.1-1.21.2-1.11.11.0-1.0
Reaction time mean minus median3.34.413.2-3.63.53.5-1.3-3.12.81.8-1.90.32.1-2.1-1.2-2.1-2.0-1.81.2-1.41.1-1.0-0.90.9
Reaction time mean minus median AUC2.53.29.9-3.13.13.0-1.2-2.62.41.5-1.60.31.7-1.8-1.0-1.7-1.6-1.50.9-1.10.9-0.9-0.80.8
Reaction time num false alarms0.50.61.00.20.20.21.0-0.50.61.0-0.8-1.00.8-0.8-0.9-0.8-0.8-0.91.0-0.90.9-0.9-0.90.9
Reaction time num false alarms AUC0.40.60.90.00.30.30.9-0.60.70.9-0.9-0.90.8-0.8-0.9-0.8-0.8-0.90.9-0.90.9-0.9-0.80.8
Reaction time trials correct on left0.71.01.50.2-0.5-0.5-0.90.9-1.0-1.21.21.0-1.11.11.01.11.11.1-1.21.2-1.11.11.0-1.0
Reaction time trials on left0.50.81.20.1-0.4-0.4-0.90.8-0.8-1.01.10.9-1.00.90.91.01.01.0-1.01.0-0.91.00.9-0.9
Reaction time mean0.60.83.8-2.01.91.9-1.3-1.10.90.3-0.10.90.3-0.50.4-0.3-0.3-0.30.00.1-0.40.20.6-0.6
Reaction time mean AUC0.60.83.9-2.01.81.8-1.5-1.00.80.10.11.10.1-0.30.6-0.1-0.1-0.1-0.20.3-0.60.50.7-0.7
Median of all reaction times0.50.71.5-1.11.11.1-1.2-0.20.1-0.30.71.2-0.40.21.00.40.50.4-0.50.8-1.00.81.1-1.1
Reaction time omissions3.64.98.8-2.72.92.9-0.1-3.02.82.3-2.2-0.72.4-2.4-1.9-2.4-2.3-2.21.8-2.01.8-1.7-1.81.8
Reaction time false alarm rate0.91.32.00.20.30.31.4-0.80.91.4-1.3-1.41.2-1.1-1.2-1.2-1.2-1.21.4-1.31.3-1.3-1.21.2
Reaction time premature initiation rate0.30.31.11.0-0.7-0.71.00.2-0.10.3-0.5-1.00.3-0.2-0.6-0.3-0.3-0.30.4-0.60.6-0.7-0.60.6
Reaction time premature initiations0.10.21.01.0-0.9-0.90.40.7-0.6-0.40.2-0.4-0.30.30.00.30.30.3-0.30.1-0.0-0.00.0-0.0
Std. dev. reaction times2.33.29.8-3.13.13.1-1.1-2.62.41.5-1.60.31.8-1.8-0.9-1.7-1.7-1.51.0-1.20.8-0.9-0.60.7
Reaction time trials completed0.50.81.20.1-0.4-0.4-0.90.8-0.8-1.01.10.9-1.00.90.91.01.01.0-1.01.0-0.91.00.9-0.9
Reaction time trials AUC0.71.01.60.3-0.5-0.6-0.91.0-1.0-1.11.21.0-1.11.11.01.11.21.1-1.11.2-1.11.11.0-1.0
Run reversals in cocaine runway, females2.52.43.4-1.31.71.70.5-1.81.81.8-1.7-0.91.7-1.8-1.4-1.7-1.6-1.71.6-1.51.5-1.4-1.41.5
Run reversals in cocaine runway, males0.30.30.60.3-0.6-0.6-0.40.5-0.5-0.70.40.4-0.50.60.30.50.50.5-0.80.4-0.40.50.5-0.7
Latency to leave start box in cocaine runway0.10.10.3-0.60.50.5-0.4-0.30.30.10.00.20.1-0.20.0-0.1-0.1-0.10.10.00.00.1-0.20.2
Latency to leave start box in cocaine runway, F0.10.10.6-0.80.70.6-0.5-0.50.40.2-0.10.30.2-0.2-0.0-0.2-0.2-0.20.0-0.10.10.0-0.20.1
Latency to leave start box in cocaine runway, M0.10.10.1-0.10.20.20.2-0.20.20.3-0.1-0.20.2-0.3-0.1-0.2-0.2-0.30.3-0.10.2-0.2-0.30.4
Std. dev. time between licks in bursts0.20.21.0-0.81.01.0-0.7-0.30.30.00.20.6-0.1-0.10.40.00.10.1-0.20.3-0.40.30.4-0.4
Total sessions with >9 infusions0.40.42.31.5-1.2-1.21.30.7-0.60.10.0-0.9-0.10.2-0.30.10.1-0.00.4-0.20.2-0.4-0.30.3
Short access day 1 total inactive lever presses2.52.89.73.1-3.0-3.01.42.5-2.2-1.31.4-0.5-1.51.60.91.51.41.3-0.60.9-0.80.70.8-0.8
Short access day 10 total inactive lever presses1.71.92.80.10.50.51.7-1.01.21.5-1.6-1.71.4-1.4-1.5-1.4-1.5-1.51.6-1.51.5-1.6-1.51.5
Short access day 1 total infusions1.01.14.12.0-1.9-1.90.91.5-1.4-0.70.8-0.4-0.91.00.40.90.80.8-0.20.5-0.40.30.4-0.4
Short access day 10 total infusions0.20.20.80.6-0.4-0.40.90.10.00.3-0.3-0.70.3-0.2-0.4-0.3-0.3-0.30.4-0.40.4-0.5-0.40.4
Short access total infusions0.30.30.80.9-0.9-0.90.20.8-0.8-0.50.60.1-0.60.60.40.60.50.5-0.30.4-0.40.40.4-0.4
Short access day 1 locomotion0.40.41.61.3-1.2-1.20.51.0-0.9-0.40.5-0.2-0.60.60.20.60.50.5-0.10.3-0.20.20.2-0.2
Short access day 10 total locomotion0.10.10.40.6-0.6-0.60.40.5-0.4-0.30.2-0.2-0.30.30.20.30.30.2-0.20.2-0.20.10.3-0.3
Short access total locomotion0.30.31.41.2-1.0-1.00.80.7-0.6-0.20.2-0.5-0.30.30.00.30.20.20.10.0-0.0-0.10.1-0.1
One hour access (0.3 mA shock)0.91.14.22.1-1.9-1.91.11.5-1.3-0.80.6-0.5-0.80.90.40.80.70.7-0.40.4-0.40.20.4-0.4
Compulsive drug intake1.01.01.6-0.10.50.50.7-0.90.91.2-1.1-1.01.1-1.0-1.1-1.1-1.1-1.11.3-1.21.1-1.1-1.11.1
One hour access (shock baseline)1.31.52.31.2-1.5-1.50.01.5-1.5-1.41.30.6-1.31.31.21.31.31.3-1.31.2-1.11.01.1-1.1
Social response proportion0.20.21.30.8-1.1-1.10.60.4-0.3-0.1-0.3-0.50.10.2-0.4-0.0-0.10.00.0-0.30.3-0.2-0.20.2
Social responses0.30.41.60.9-0.7-0.71.30.2-0.00.5-0.5-1.00.3-0.3-0.6-0.3-0.4-0.40.8-0.60.6-0.6-0.50.5
Social time0.81.03.61.9-1.8-1.80.91.5-1.3-0.80.8-0.3-0.90.90.40.90.90.8-0.40.6-0.40.40.3-0.3
Soleus weight0.31.03.71.6-1.0-1.01.90.3-0.00.6-0.9-1.70.6-0.5-0.9-0.6-0.6-0.70.8-0.91.0-1.2-0.80.9
Bone: stiffness0.61.02.0-0.20.20.20.6-0.91.00.8-1.4-1.01.3-1.0-1.4-1.2-1.2-1.00.5-1.41.3-1.2-0.90.8
Tibialis anterior weight2.48.318.04.2-4.2-4.20.94.0-3.8-2.92.70.4-3.03.12.33.02.92.7-2.12.2-2.11.92.1-2.0
Time to tail flick, vehicle, before self-admin0.30.30.5-0.20.30.30.3-0.50.60.5-0.7-0.40.6-0.6-0.7-0.6-0.6-0.60.5-0.60.5-0.6-0.40.4
Time to tail flick, vehicle, after self-admin1.11.21.7-0.20.60.61.1-0.91.01.3-1.2-1.11.1-1.1-1.2-1.1-1.2-1.21.3-1.21.2-1.2-1.21.2
Time to tail flick, test, before self-admin0.40.30.50.2-0.4-0.4-0.40.6-0.6-0.70.50.5-0.70.60.70.70.70.6-0.70.7-0.60.60.6-0.6
Time to tail flick, test, after self-admin0.50.52.01.4-1.3-1.30.61.0-0.9-0.50.4-0.3-0.60.60.20.60.50.5-0.20.3-0.20.20.2-0.2
Delta time to tail flick, vehicle, before/after SA0.50.50.8-0.10.40.40.7-0.60.60.9-0.7-0.80.7-0.8-0.6-0.7-0.8-0.80.9-0.80.8-0.8-0.80.8
Delta time to tail flick, test, before/after SA0.10.10.1-0.10.10.10.2-0.20.20.3-0.2-0.20.3-0.3-0.3-0.3-0.3-0.30.3-0.30.3-0.3-0.30.3
Tibia length0.71.96.71.8-1.0-1.02.60.10.21.4-1.1-2.20.8-0.8-1.5-0.9-1.0-1.11.9-1.31.4-1.5-1.41.4
Ambulatory time before self-admin0.00.00.00.1-0.1-0.10.20.0-0.00.0-0.1-0.10.0-0.0-0.1-0.0-0.0-0.00.1-0.10.0-0.1-0.0-0.0
Ambulatory time after self-admin0.20.20.7-0.60.40.4-0.9-0.1-0.0-0.30.40.7-0.30.20.40.30.30.3-0.40.4-0.50.50.4-0.4
Bone: tissue strength0.30.30.7-0.4-0.10.0-0.80.2-0.3-0.50.50.7-0.40.50.60.40.40.5-0.50.5-0.60.60.6-0.6
Total heroin consumption0.50.63.21.8-1.5-1.51.21.0-0.9-0.20.3-0.8-0.40.5-0.20.40.30.30.20.00.1-0.1-0.10.1
Bone: trabecular number2.94.57.42.3-2.6-2.6-0.22.7-2.6-2.42.20.8-2.22.41.82.22.22.2-2.11.9-1.81.71.9-1.9
Bone: trabecular spacing1.11.57.8-2.82.22.3-2.3-1.41.10.1-0.11.50.3-0.40.5-0.3-0.3-0.2-0.30.3-0.50.60.4-0.4
Bone: trabecular thickness0.70.82.91.7-1.5-1.50.71.3-1.2-0.70.7-0.3-0.80.90.30.80.80.7-0.50.5-0.40.30.4-0.4
Bone: trabecular tissue density2.23.15.9-2.12.42.4-0.0-2.32.31.9-1.8-0.71.9-2.0-1.3-1.9-1.8-1.81.6-1.51.3-1.4-1.31.3
Water consumed over 24 hours1.01.22.41.2-1.5-1.5-0.11.4-1.4-1.21.10.5-1.21.30.71.21.11.1-1.01.0-0.80.90.6-0.6
Number of responses in last shaping day0.20.20.3-0.10.30.30.6-0.40.40.4-0.3-0.40.4-0.5-0.5-0.4-0.4-0.50.3-0.30.4-0.5-0.40.4