Hub : Genes

Nt5c3b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Nt5c3b 0.13 0.06 4.5e-12 0.16 0.15 0.15 0.16 1.3e-14 8.1e-14 7.0e-14 1.4e-14
2 IL gene expression Nt5c3b 0.14 0.08 4.5e-03 0.03 0.11 0.03 0.04 7.4e-02 1.4e-03 5.5e-02 3.3e-02
3 Brain gene expression Nt5c3b 0.04 0.02 2.9e-05 0.07 0.05 0.05 0.06 2.9e-07 3.5e-05 9.3e-06 2.1e-06
4 PL intron excision ratio chr10_85374593_85374678 0.03 0.02 9.1e-03 0 0 -0 0 2.2e-01 1.6e-01 4.3e-01 2.6e-01
5 Liver gene expression Nt5c3b 0.02 0.01 5.5e-03 0.01 0.01 -0 0 5.7e-02 5.4e-02 5.5e-01 1.1e-01
6 OFC gene expression Nt5c3b 0.14 0.07 2.6e-03 -0 0.06 -0.01 0.01 3.7e-01 1.7e-02 6.1e-01 2.3e-01
7 Liver intron excision ratio chr10_85370652_85374547 0.07 0.05 2.2e-03 -0 0.01 0 -0 5.6e-01 4.4e-02 3.7e-01 5.4e-01
8 BLA gene expression Nt5c3b 0.06 0.04 1.3e-03 0 0.03 0.01 0.01 2.5e-01 1.4e-02 1.5e-01 8.2e-02
9 Adipose gene expression Nt5c3b 0.02 0.01 9.0e-04 0.01 0.02 0.02 0.02 1.9e-02 1.7e-03 1.4e-03 2.9e-03
10 PL gene expression Nt5c3b 0.03 0.02 1.4e-04 0.02 0.03 0.01 0.03 1.5e-03 1.0e-04 3.7e-02 4.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.40.71.61.11.1-1.01.3-0.40.8-0.20.9-0.60.7
Area under the delay curve0.60.62.6-0.5-1.00.4-1.60.3-0.5-0.7-0.60.7-0.8
BMI with tail0.20.71.8-1.3-0.51.4-0.20.2-0.70.9-0.90.90.0
BMI without tail1.53.06.9-2.6-1.32.4-0.21.3-1.7-1.4-1.91.8-1.5
Body weight0.31.45.6-0.1-1.40.1-1.80.8-1.02.4-0.81.1-0.0
Weight adjusted by age2.73.05.7-1.4-1.61.4-0.82.1-1.7-2.4-1.61.6-2.3
Bone surface0.10.20.90.90.1-0.80.50.6-0.1-0.10.20.20.0
Bone volume0.20.41.21.10.5-0.91.10.40.20.20.6-0.20.5
Breakpoint value in progressive ratio session0.40.52.0-0.40.70.21.2-0.40.4-1.4-0.00.2-0.3
Number of licking bursts1.31.52.40.81.6-0.81.4-1.41.21.21.0-1.21.4
Context. condit. distance diff. score2.73.37.7-1.8-2.21.8-2.80.9-1.5-1.5-1.71.6-1.7
Locomotion velocity, session 10.10.10.40.10.0-0.20.60.6-0.2-0.10.0-0.0-0.1
Locomotion distance, session 10.70.91.4-0.8-1.10.8-0.81.2-1.2-0.3-1.01.0-0.9
Locomotion velocity, session 20.00.00.20.0-0.2-0.0-0.2-0.10.1-0.50.2-0.0-0.1
Locomotion distance, session 20.00.00.20.1-0.1-0.2-0.30.1-0.20.5-0.1-0.00.1
Locomotion velocity, session 30.70.81.7-1.0-1.01.0-1.30.4-0.7-1.1-0.80.7-0.9
Locomotion distance, session 31.11.21.6-1.0-1.20.9-1.11.1-1.1-1.0-1.11.1-1.2
Stereotopy head waving bouts, day 31.41.72.41.41.2-1.30.5-1.61.41.11.4-1.31.5
Stereotopy head waving duration, day 30.30.40.90.80.4-0.6-0.0-0.60.50.90.7-0.70.8
Locomotion velocity, session 70.20.21.40.1-0.4-0.2-0.50.3-0.41.2-0.10.00.2
Locomotion distance, session 71.72.13.5-0.9-1.91.0-1.81.8-1.7-0.5-1.41.4-1.5
Stereotopy head waving bouts, day 71.61.83.21.21.5-1.00.9-1.81.60.51.5-1.31.4
Stereotopy head waving duration, day 72.32.84.61.51.9-1.41.2-2.12.00.91.8-1.71.8
Locomotion velocity, session 81.31.66.1-0.8-1.60.7-2.50.6-1.31.2-1.20.9-0.5
Locomotion distance, session 80.91.33.4-1.2-1.41.1-1.90.6-1.0-0.8-1.00.9-1.0
Degree of sensitization distance0.50.51.3-0.0-1.10.2-1.20.8-0.80.6-0.40.6-0.4
Degree of sensitization stereotypy1.21.32.31.01.4-0.81.2-1.51.40.11.3-1.11.2
Conditioned locomotion0.10.10.40.00.5-0.20.4-0.60.5-0.20.3-0.40.2
Cocaine response after cond. corrected0.20.20.40.40.6-0.50.6-0.40.40.10.4-0.30.4
Cocaine response after cond. not corrected0.40.41.10.80.6-1.10.4-0.30.50.70.6-0.40.5
Cocaine response before conditioning0.30.41.10.9-0.1-1.0-0.60.00.21.00.2-0.30.1
Saline control response0.20.20.50.2-0.4-0.1-0.60.6-0.40.1-0.50.7-0.5
Bone: connectivity density0.50.81.71.01.1-0.91.3-0.61.0-0.51.0-0.70.7
Bone: cortical apparent density3.85.07.12.72.4-2.51.5-2.12.21.82.3-2.32.3
Bone: cortical area0.50.72.71.60.3-1.50.20.10.50.70.9-0.40.5
Bone: cortical porosity1.41.55.5-1.3-0.61.40.51.1-0.9-2.3-0.91.0-1.2
Bone: cortical porosity1.11.23.7-1.2-0.61.30.31.0-0.9-1.9-0.91.0-1.1
Bone: cortical thickness1.42.34.72.21.0-2.2-0.0-1.41.61.31.7-1.31.4
Bone: cortical thickness1.11.32.31.20.8-1.30.1-1.31.5-0.91.5-1.30.6
Bone: cortical tissue density3.74.96.92.62.4-2.41.6-2.12.21.72.3-2.32.3
Condit. Reinf. active minus inactive responses0.10.10.70.10.20.20.0-0.30.3-0.80.1-0.1-0.1
Condit. Reinf. active-inactive response ratio0.20.21.7-0.20.20.50.1-0.40.4-1.30.10.1-0.3
Condit. Reinf. active responses0.10.10.20.40.3-0.10.0-0.40.3-0.50.2-0.10.1
Condit. Reinf. inactive responses0.10.20.70.80.2-0.7-0.2-0.00.00.60.2-0.20.4
Incentive salience index mean0.10.10.40.40.4-0.10.1-0.60.5-0.50.3-0.20.1
Condit. Reinf. lever presses0.10.10.30.50.1-0.3-0.5-0.40.10.4-0.10.20.1
Condit. Reinf. active minus inactive responses0.40.51.20.70.7-0.71.1-0.30.7-0.70.9-0.80.3
Condit. Reinf. active-inactive response ratio0.10.10.40.1-0.0-0.20.30.4-0.0-0.6-0.00.1-0.5
Condit. Reinf. active responses0.81.12.90.91.1-0.91.7-0.30.9-0.91.2-1.20.5
Condit. Reinf. inactive responses1.11.32.61.11.3-1.11.6-0.71.0-0.11.3-1.41.0
Condit. Reinf. lever presses0.60.84.9-0.8-0.50.90.00.6-0.4-2.2-0.30.3-0.9
Condit. Reinf. lever reinforcers received0.60.92.20.71.0-0.71.5-0.40.8-1.21.1-1.10.4
Conditioned reinforcement - actives0.90.92.3-1.1-0.50.90.21.0-0.7-1.5-0.81.0-1.1
Conditioned reinforcement - inactives1.61.83.51.81.3-1.91.1-0.61.01.81.1-1.01.2
Conditioned locomotion3.44.19.7-2.3-1.22.00.52.3-1.8-3.1-1.91.8-2.3
Patch foraging indifference point 0 sec0.10.10.50.4-0.3-0.5-0.50.10.2-0.70.20.1-0.4
Patch foraging indifference point AUC0.30.30.70.30.7-0.40.8-0.50.7-0.30.6-0.50.3
Delay disc. indifference point, 0s delay0.10.10.7-0.0-0.30.2-0.40.3-0.2-0.8-0.10.4-0.4
Delay disc. indifference point, 16s delay0.50.62.5-0.5-0.60.4-1.6-0.40.1-1.1-0.40.5-0.7
Delay disc. indifference point, 2s delay0.10.10.50.20.2-0.10.70.50.0-0.70.2-0.0-0.2
Delay disc. indifference point, 24s delay1.31.24.0-0.7-1.50.3-2.00.8-0.9-1.0-0.80.9-1.2
Delay disc. indifference point, 4s delay0.10.10.6-0.2-0.30.3-0.7-0.00.1-0.7-0.10.1-0.4
Delay disc. indifference point, 8s delay0.70.72.3-0.3-1.20.2-1.50.8-0.9-0.1-0.80.7-0.8
Indifference point function ln k0.30.41.60.8-0.4-0.8-1.2-0.20.10.90.4-0.30.4
Indifference point function log k0.30.41.60.8-0.4-0.8-1.2-0.20.10.90.4-0.30.4
Patch foraging total patch changes 0 sec0.10.10.40.3-0.4-0.5-0.40.20.1-0.60.20.2-0.4
Patch foraging total patch changes 12 sec1.21.64.40.91.6-1.22.1-0.71.4-0.91.4-1.00.6
Patch foraging total patch changes 18 sec0.20.21.2-0.20.3-0.10.90.10.3-1.10.20.0-0.3
Patch foraging total patch changes 24 sec0.20.20.90.10.3-0.30.2-0.30.5-1.00.4-0.4-0.0
Patch foraging total patch changes 6 sec0.20.42.3-0.4-0.40.2-0.10.4-0.0-1.5-0.20.3-0.9
Patch foraging time to switch 0 sec0.60.92.8-1.1-0.51.30.00.6-0.7-1.7-0.80.6-1.0
Patch foraging water rate 0 sec0.00.10.20.0-0.2-0.3-0.40.1-0.10.4-0.00.30.1
Patch foraging water rate 12 sec0.10.20.30.50.3-0.50.4-0.20.40.20.6-0.60.4
Patch foraging water rate 18 sec2.23.05.72.21.0-2.1-0.5-1.71.52.41.7-1.41.9
Patch foraging water rate 24 sec0.10.10.2-0.3-0.10.40.10.1-0.2-0.5-0.20.2-0.2
Patch foraging water rate 6 sec1.01.52.11.31.2-1.40.6-1.41.40.61.5-1.41.3
Seeking ratio, delayed vs. immediate footshock0.30.31.8-0.4-0.60.7-1.3-0.4-0.2-0.4-0.3-0.1-0.2
Distance traveled before self-admin2.83.04.2-1.8-1.71.8-1.02.0-1.7-2.0-1.61.5-1.9
Distance traveled after self-admin0.60.62.1-1.5-0.61.3-0.20.3-0.7-0.4-0.70.7-0.4
Extensor digitorum longus weight5.320.827.8-4.4-5.34.5-4.34.7-5.2-2.0-4.95.0-4.4
Bone: elastic displacement2.73.05.1-1.9-1.51.8-0.41.9-1.8-2.3-1.71.5-1.9
Bone: elastic work1.21.54.3-1.2-1.01.2-0.21.3-1.2-2.1-1.11.0-1.3
Bone: endosteal estimation2.04.410.1-1.6-2.11.8-0.53.2-2.5-1.6-2.02.2-2.2
Bone: endosteal perimeter0.71.34.0-0.7-0.90.90.42.0-1.4-0.9-1.11.3-1.2
Epididymis fat weight0.10.20.8-0.1-0.30.2-0.30.4-0.40.9-0.70.7-0.2
Delta time in closed arm before/after self-admin0.40.42.20.00.10.1-0.5-0.50.21.50.1-0.50.7
Delta time in open arm before/after self-admin0.10.10.50.40.4-0.30.7-0.10.30.00.10.50.0
Diff in mean of infusions in LGA sessions1.92.14.2-1.9-1.01.7-0.11.3-1.4-2.0-1.51.2-1.5
Delay discount exponential model param0.70.73.00.61.1-0.41.7-0.30.50.70.7-0.60.8
Extinction: sum of active levers before priming2.42.43.5-1.5-1.51.5-0.71.9-1.8-1.1-1.71.7-1.6
Active lever presses in extinction session 60.70.62.4-0.70.60.71.50.20.1-1.6-0.20.2-0.4
Bone: final force1.32.25.32.31.0-2.30.6-0.61.21.61.6-1.21.3
Bone: final moment1.11.84.92.20.7-2.10.4-0.30.91.51.4-1.01.2
Food consumed during 24 hour testing period0.20.20.9-0.00.10.1-0.4-0.60.30.90.1-0.40.5
Glucose0.20.31.1-1.00.11.10.70.1-0.3-0.4-0.30.0-0.0
Heart weight0.81.12.9-0.7-1.20.7-1.70.6-0.91.3-1.21.1-0.6
Delay discount hyperbolic model param0.60.62.30.61.0-0.51.5-0.40.50.80.6-0.60.9
Intermittent access intake day 1-15 change3.63.55.11.72.2-1.82.0-1.61.52.01.7-1.82.3
Intermittent access intake escalation4.74.66.32.02.5-2.12.2-2.01.92.11.9-2.12.5
Intermittent access intake escalation 22.72.74.21.31.9-1.51.7-1.51.31.81.4-1.62.0
Intermitt. access day 1 inactive lever presses1.41.52.41.31.3-1.50.3-1.51.41.40.9-0.91.2
Intermitt. access day 15 inactive lever presses3.03.37.22.62.0-2.71.8-1.11.71.11.7-1.21.5
Intermitt. access escalation Index0.20.21.5-0.1-0.60.2-1.2-0.1-0.20.4-0.1-0.10.1
Intermittent access day 1 total infusions0.40.40.8-0.0-0.70.1-0.70.9-0.5-0.4-0.70.8-0.8
Intermittent access day 15 total infusions0.91.01.81.21.1-1.30.7-0.81.00.90.9-1.11.0
Intermittent access terminal intake (last 3 days)0.91.01.71.31.0-1.30.5-0.60.81.00.9-1.31.0
Intermittent access total infusions0.10.10.40.60.1-0.6-0.30.00.20.40.2-0.50.1
Intermittent access day 1 locomotion0.40.41.40.1-0.2-0.20.61.2-0.5-0.4-0.50.8-0.7
Intermittent access day 15 total locomotion0.90.93.90.91.1-1.22.00.20.30.70.6-0.40.8
Intermittent access total locomotion0.40.52.90.50.9-0.71.70.10.30.00.3-0.10.4
Intermittent access standard deviation1.31.42.71.11.6-1.31.6-1.01.00.70.9-1.01.2
Left kidney weight0.61.73.71.00.3-0.9-1.5-1.91.41.81.0-1.01.3
Right kidney weight0.61.73.30.91.0-1.0-0.2-1.81.51.81.2-1.31.5
Cocaine induced anxiety0.50.63.5-0.5-0.90.3-1.90.0-0.60.4-0.80.2-0.4
Post-drug Anxiety0.50.53.0-0.4-0.70.3-1.7-0.1-0.50.5-0.90.6-0.4
Baseline Anxiety0.30.30.8-0.2-0.10.50.60.8-0.5-0.7-0.40.9-0.6
Tail length1.03.04.3-1.5-1.91.2-1.71.7-1.6-1.5-1.92.1-2.0
Length with tail0.51.77.90.5-1.7-0.6-2.81.0-0.91.3-0.81.1-0.6
Length without tail1.32.810.62.4-0.0-2.2-1.6-0.60.73.31.0-0.81.3
Times rat made contact with spout0.10.10.6-0.10.30.10.60.1-0.20.8-0.20.20.3
Lifetime Intake0.10.20.60.7-0.0-0.7-0.50.30.20.10.1-0.4-0.1
Liver weight, left0.10.20.3-0.4-0.40.4-0.50.2-0.3-0.6-0.2-0.2-0.4
Liver weight, right0.81.32.90.71.2-0.70.6-1.71.7-0.11.3-1.31.0
Locomotor activity0.71.13.50.21.4-0.51.9-0.91.1-0.41.1-1.40.8
Locomotor testing distance0.71.24.20.31.4-0.32.1-0.81.0-1.01.1-1.20.7
Locomotor testing rearing0.81.28.7-0.80.50.71.2-0.20.4-2.90.3-0.4-0.5
Locomotion in novel chamber0.30.42.40.30.3-0.30.1-0.40.6-1.50.7-0.7-0.2
Locomotion in novel chamber post-restriction0.10.21.30.00.50.01.20.3-0.0-0.00.1-0.10.2
Fecal boli incidents, locomotor time 10.40.52.70.10.80.21.7-0.20.20.70.4-0.10.8
Change in fecal boli incidents, locomotor task0.50.51.40.40.5-1.0-0.3-1.21.00.40.5-0.60.5
Time >=10cm from walls, locomotor time 11.81.83.71.90.9-1.90.0-1.31.21.21.3-1.31.2
Bouts of movement, locomotor time 10.10.20.50.1-0.30.2-0.60.1-0.30.7-0.30.50.1
Total resting periods, locomotor time 10.30.41.0-0.3-0.60.6-0.50.6-0.70.5-0.71.0-0.3
Rest time, locomotor task time 10.30.30.7-0.6-0.00.80.80.5-0.4-0.2-0.40.8-0.2
Distance moved, locomotor task time 10.20.20.80.6-0.2-0.7-0.9-0.20.2-0.30.2-0.2-0.1
Vertical activity count, locomotor time 10.20.30.5-0.0-0.60.2-0.70.6-0.6-0.5-0.50.4-0.6
Time >=10cm from walls, locomotor time 22.83.04.82.21.7-1.81.1-1.91.90.91.9-1.81.7
Bouts of movement, locomotor time 20.91.02.1-0.7-1.10.8-1.40.7-0.9-1.1-1.10.7-1.2
Total resting periods, locomotor time 21.11.23.6-0.7-1.30.8-1.90.7-1.0-0.8-1.20.8-1.2
Rest time, locomotor task time 20.40.41.5-0.6-0.50.5-0.70.2-0.71.2-0.80.6-0.1
Distance moved, locomotor task time 20.20.20.60.5-0.40.1-0.50.4-0.1-0.80.00.3-0.5
Vertical activity count, locomotor time 21.31.43.3-0.9-1.21.3-0.61.4-1.1-1.8-0.91.1-1.3
Light reinforcement 10.40.71.20.80.9-1.10.7-0.81.0-0.30.9-0.80.5
Light reinforcement 20.10.10.80.10.1-0.20.1-0.00.1-0.90.10.0-0.2
Bone: marrow area1.84.09.3-1.6-2.11.7-0.53.0-2.4-1.5-1.92.1-2.1
Bone: maximum diameter0.30.51.71.30.4-1.20.80.30.40.20.7-0.30.2
Bone: maximum force0.20.31.01.0-0.3-0.9-0.10.8-0.20.40.20.20.0
Bone: maximum moment0.20.31.20.8-0.6-0.7-0.31.1-0.50.2-0.00.4-0.2
Mean time between licks in bursts0.20.31.9-0.40.50.20.7-0.4-0.01.4-0.2-0.30.6
Mean num. licks in bursts1.51.82.6-1.1-1.51.2-1.11.6-1.5-0.9-1.41.5-1.4
Cd content in liver1.71.94.1-2.0-1.22.0-1.00.6-1.2-1.2-1.51.3-1.2
Co content in liver0.10.10.4-0.4-0.50.5-0.6-0.1-0.1-0.30.1-0.0-0.2
Cu content in liver0.10.10.3-0.1-0.10.1-0.3-0.10.0-0.5-0.20.6-0.4
Fe content in liver0.10.10.60.1-0.2-0.1-0.8-0.30.10.2-0.10.3-0.1
K content in liver5.65.57.82.32.6-2.41.9-2.62.80.82.7-2.52.3
Mg content in liver5.65.88.42.52.6-2.51.8-2.62.90.92.8-2.62.2
Mn content in liver13.114.918.83.94.1-3.92.6-4.24.32.64.2-4.34.0
Na content in liver0.70.83.00.91.2-0.81.7-0.10.40.30.7-0.60.8
Rb content in liver2.12.63.91.51.7-1.51.2-1.92.00.41.9-2.01.4
Se content in liver2.93.55.91.42.4-1.61.9-2.32.30.71.8-1.71.8
Sr content in liver0.10.10.40.30.2-0.30.1-0.40.60.10.5-0.40.2
Zn content in liver0.10.10.4-0.20.50.10.4-0.50.4-0.60.2-0.10.1
Bone: minimum diameter0.40.72.0-0.4-0.90.6-0.11.4-1.0-0.9-0.60.7-0.8
Time in familiar zone, hab. session 11.61.52.61.11.2-1.10.5-1.41.21.21.1-1.61.3
Time in novel zone, hab. session 10.30.30.5-0.6-0.20.50.50.7-0.4-0.7-0.30.4-0.5
Total zone transitions, hab. session 12.23.07.2-1.7-2.21.9-2.71.1-1.8-0.6-1.81.3-1.5
Total locomotion distance, hab. session 10.40.53.0-0.5-0.90.7-1.7-0.0-0.4-0.4-0.5-0.0-0.5
Locomotion velocity, hab. session 10.60.93.6-0.8-1.21.0-1.90.2-0.7-0.6-0.70.3-0.7
Time in familiar zone, hab. session 21.51.53.10.81.6-0.91.1-1.81.50.71.0-1.21.4
Time in novel zone, hab. session 20.20.20.8-0.2-0.60.2-0.00.9-0.5-0.3-0.00.2-0.4
Total zone transitions, hab. session 21.01.32.0-1.1-1.41.2-1.31.1-1.3-0.3-1.21.1-1.0
Total locomotion distance, hab. session 20.10.20.3-0.6-0.50.6-0.50.3-0.50.2-0.40.3-0.2
Locomotion velocity, hab. session 20.40.60.9-1.0-0.91.0-0.90.5-0.8-0.1-0.70.6-0.5
Novel to familiar place preference ratio0.70.81.5-0.7-0.90.6-0.90.8-0.7-1.2-0.80.9-1.1
Novelty place preference0.50.51.1-0.4-0.80.4-0.90.6-0.4-1.0-0.50.6-0.9
Time in novel zone, NPP test0.10.10.5-0.0-0.4-0.1-0.50.2-0.0-0.7-0.10.2-0.5
Total zone transitions, NPP test1.72.43.3-1.5-1.81.5-1.41.7-1.8-0.6-1.71.7-1.5
Total locomotion distance, NPP test0.30.50.8-0.5-0.90.7-0.80.8-0.8-0.0-0.70.6-0.6
Locomotion velocity, NPP test1.41.92.7-1.3-1.61.4-1.51.4-1.6-0.6-1.51.4-1.3
Intraocular pressure4.56.38.7-2.5-2.62.6-1.72.4-2.5-2.2-2.72.9-2.8
Delta distance traveled before/after self-admin1.71.83.80.61.4-0.60.9-2.01.41.71.1-1.31.8
Delta ambulatory time before/after self-admin1.21.42.80.51.2-0.50.9-1.61.01.70.9-1.01.6
Parametrial fat weight0.10.10.50.30.4-0.50.70.30.10.20.00.30.0
Pavlov. Cond. lever latency1.21.63.2-1.8-1.01.60.21.3-1.2-1.4-1.21.0-1.2
Pavlov. Cond. magazine entry latency3.54.45.52.32.3-2.21.5-2.32.21.12.3-2.22.2
Pavlov. Cond. change in total contacts2.42.64.81.91.5-1.80.1-2.22.00.91.6-1.61.4
Pavlov. Cond. index score2.22.85.02.21.7-2.10.7-1.71.61.41.7-1.51.7
Pavlov. Cond. latency score2.32.95.22.31.6-2.10.5-1.71.61.71.7-1.51.8
Pavlov. Cond. lever contacts0.80.92.01.40.7-1.3-0.2-1.00.81.40.7-0.70.9
Pavlov. Cond. magazine entry number3.94.97.0-2.7-2.42.4-1.42.3-2.3-1.2-2.42.3-2.2
Pavlov. Cond. intertrial magazine entries0.70.91.6-1.3-0.91.1-0.60.8-1.0-0.4-1.11.1-0.8
Pavlov. Cond. lever-magazine prob. diff.2.32.84.52.11.8-2.00.9-1.81.71.31.7-1.51.7
Pavlov. Cond. response bias1.62.03.41.91.4-1.70.4-1.61.60.41.5-1.41.2
Pavlov. Cond. lever latency0.20.21.10.2-0.3-0.2-0.70.1-0.21.0-0.40.5-0.1
Pavlov. Cond. magazine entry latency0.00.10.1-0.3-0.30.3-0.10.2-0.2-0.30.0-0.1-0.2
Pavlov. Cond. change in total contacts0.30.41.00.50.6-0.40.9-0.40.6-0.51.0-1.00.5
Pavlov. Cond. index score0.10.20.8-0.30.10.30.70.10.1-0.90.4-0.50.0
Pavlov. Cond. latency score0.10.20.7-0.40.00.40.60.2-0.0-0.80.3-0.4-0.0
Pavlov. Cond. lever contacts0.20.20.9-0.40.30.30.7-0.20.2-1.00.3-0.50.1
Pavlov. Cond. magazine entry number0.20.20.9-0.3-0.20.3-0.40.3-0.40.0-0.80.9-0.5
Pavlov. Cond. intertrial magazine entries0.50.72.90.9-0.4-0.7-1.7-0.50.31.4-0.10.20.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.20.10.20.60.00.1-0.80.4-0.50.1
Pavlov. Cond. response bias0.20.30.80.10.5-0.10.7-0.40.5-0.60.7-0.90.4
Time in closed arm before self-admin0.50.51.10.30.9-0.21.0-1.00.9-0.70.7-0.20.5
Time in closed arm after self-admin0.30.31.6-0.50.50.50.1-1.30.7-0.30.3-0.20.4
Time in open arm before self-admin0.30.31.6-0.2-0.60.3-1.20.2-0.41.0-0.4-0.20.0
Time in open arm after self-admin0.20.20.60.6-0.3-0.4-0.20.6-0.30.8-0.20.4-0.1
Bone: periosteal estimation0.30.73.20.1-0.90.00.11.8-1.0-0.7-0.50.9-0.9
Bone: periosteal perimeter0.20.31.3-0.0-0.40.10.51.1-0.6-0.4-0.30.5-0.5
Bone: post-yield work0.50.72.0-0.6-1.20.5-1.40.8-0.80.1-0.60.6-0.7
Progressive ratio test 1 active lever presses0.10.10.40.70.0-0.4-0.20.10.20.10.2-0.0-0.1
Progressive ratio test 1 breakpoint0.10.10.40.70.2-0.40.00.10.20.00.2-0.1-0.1
Progressive ratio test 1 inactive lever presses0.70.82.21.30.8-1.50.2-0.71.10.60.9-0.60.5
Progressive ratio test 2 active lever presses0.40.51.51.20.6-1.20.50.10.40.60.5-0.40.4
Progressive ratio test 2 breakpoint0.30.41.31.20.4-1.10.50.30.20.60.4-0.20.3
Progressive ratio test 2 inactive lever presses0.91.03.41.50.8-1.80.4-0.20.61.20.7-0.70.8
Incentive Sensitization - Responses0.30.30.90.90.2-0.90.70.8-0.30.30.2-0.10.1
Incentive Sensitization - Breakpoint0.30.41.01.00.3-0.90.80.7-0.20.30.3-0.20.2
Sum of active levers in priming session hrs 5-60.50.51.0-0.20.80.40.9-0.70.8-1.00.6-0.70.2
Progressive ratio0.10.10.30.20.10.30.30.2-0.3-0.6-0.10.6-0.1
Food seeking constrained by brief footshock0.10.10.30.50.3-0.60.0-0.40.40.10.4-0.10.3
Seeking ratio, punishment vs. effort0.10.10.3-0.00.1-0.5-0.1-0.30.40.50.2-0.50.2
Retroperitoneal fat weight0.10.21.10.3-0.3-0.2-0.7-0.10.01.0-0.00.30.2
Reaction time number correct0.10.10.7-0.1-0.4-0.0-0.60.1-0.30.9-0.2-0.00.0
Reaction time mean minus median0.20.21.0-0.2-0.50.30.21.0-0.6-0.3-0.40.3-0.6
Reaction time mean minus median AUC0.10.20.60.0-0.20.00.40.7-0.3-0.70.0-0.1-0.5
Reaction time num false alarms0.81.13.60.31.4-0.41.9-1.01.00.40.9-1.01.0
Reaction time num false alarms AUC0.91.23.50.51.4-0.71.9-0.91.00.81.0-1.01.1
Reaction time trials correct on left0.10.10.7-0.1-0.4-0.0-0.60.1-0.30.9-0.2-0.00.0
Reaction time trials on left0.10.10.7-0.0-0.3-0.1-0.50.1-0.30.8-0.2-0.10.1
Reaction time mean1.01.42.21.21.3-1.11.4-0.91.5-0.51.5-1.40.7
Reaction time mean AUC0.60.81.30.80.9-0.61.2-0.51.1-1.11.1-1.00.2
Median of all reaction times1.92.74.11.61.9-1.51.8-1.52.0-0.52.0-1.81.1
Reaction time omissions1.41.82.81.51.5-1.31.6-1.21.5-0.21.7-1.61.0
Reaction time false alarm rate0.71.03.70.41.4-0.51.9-0.80.90.20.9-0.70.9
Reaction time premature initiation rate0.10.10.6-0.20.30.10.1-0.30.3-0.8-0.10.1-0.2
Reaction time premature initiations0.00.00.1-0.3-0.10.2-0.3-0.10.0-0.3-0.30.1-0.3
Std. dev. reaction times0.20.31.80.50.6-0.41.30.20.3-0.30.5-0.50.1
Reaction time trials completed0.10.10.7-0.0-0.3-0.1-0.50.1-0.30.8-0.2-0.10.1
Reaction time trials AUC0.10.10.80.0-0.2-0.1-0.5-0.0-0.20.9-0.1-0.20.2
Run reversals in cocaine runway, females1.11.15.2-0.2-1.30.4-2.30.4-0.5-0.2-0.91.2-0.9
Run reversals in cocaine runway, males0.20.21.00.0-0.70.0-1.00.6-0.4-0.2-0.2-0.2-0.5
Latency to leave start box in cocaine runway0.30.30.7-0.6-0.40.3-0.80.1-0.50.6-0.70.8-0.2
Latency to leave start box in cocaine runway, F1.31.42.8-1.6-1.01.4-0.90.7-1.1-0.4-1.51.7-1.1
Latency to leave start box in cocaine runway, M0.50.40.91.00.4-1.0-0.2-0.60.60.40.8-0.70.6
Std. dev. time between licks in bursts0.20.20.6-0.60.20.40.70.2-0.2-0.8-0.20.3-0.2
Total sessions with >9 infusions0.50.61.6-0.5-0.60.6-0.50.7-0.5-1.3-0.80.7-1.1
Short access day 1 total inactive lever presses0.60.62.31.30.3-1.5-0.2-0.10.61.00.5-0.80.4
Short access day 10 total inactive lever presses0.40.40.9-0.2-0.8-0.1-0.90.7-0.6-0.3-0.70.8-0.8
Short access day 1 total infusions0.40.41.31.20.0-1.0-0.7-0.10.7-0.00.5-0.6-0.1
Short access day 10 total infusions0.40.41.50.1-0.60.2-0.41.2-0.7-0.5-0.70.5-0.9
Short access total infusions0.20.20.80.9-0.2-0.6-0.80.30.3-0.20.1-0.3-0.4
Short access day 1 locomotion0.50.53.90.00.10.10.60.40.2-2.00.00.0-0.8
Short access day 10 total locomotion0.70.75.30.60.9-0.72.30.7-0.0-0.30.1-0.00.0
Short access total locomotion0.30.30.90.3-0.0-0.20.70.9-0.3-0.8-0.30.3-0.6
One hour access (0.3 mA shock)0.10.10.50.0-0.2-0.10.10.7-0.3-0.4-0.10.0-0.4
Compulsive drug intake0.70.71.3-0.4-1.10.3-1.10.8-0.8-0.4-0.61.0-1.0
One hour access (shock baseline)0.00.00.1-0.20.00.10.10.3-0.1-0.3-0.1-0.4-0.1
Social response proportion1.41.53.6-1.9-1.11.6-1.10.4-0.9-0.9-1.31.2-1.1
Social responses0.10.10.5-0.7-0.10.6-0.1-0.30.1-0.6-0.20.1-0.2
Social time0.40.52.1-0.0-0.60.1-0.11.4-1.00.2-0.80.5-0.8
Soleus weight0.10.30.7-0.7-0.30.60.50.8-0.80.1-0.50.6-0.2
Bone: stiffness0.60.92.61.60.4-1.5-0.2-0.40.81.30.9-0.40.7
Tibialis anterior weight1.03.44.3-1.8-2.11.9-1.81.8-2.0-1.1-2.02.0-1.8
Time to tail flick, vehicle, before self-admin0.10.10.6-0.5-0.30.8-0.10.3-0.20.4-0.10.10.0
Time to tail flick, vehicle, after self-admin4.24.57.0-2.2-2.12.7-1.02.2-2.1-1.9-2.12.2-2.4
Time to tail flick, test, before self-admin0.80.81.3-0.9-0.90.7-0.11.1-0.9-0.9-0.81.1-1.0
Time to tail flick, test, after self-admin0.70.71.00.90.9-1.00.9-0.60.90.70.9-0.50.8
Delta time to tail flick, vehicle, before/after SA1.11.12.4-0.7-0.70.80.51.5-1.1-1.0-1.11.2-1.3
Delta time to tail flick, test, before/after SA0.60.60.90.80.6-0.90.2-0.80.90.50.9-1.00.6
Tibia length0.51.48.30.8-0.3-0.9-1.5-0.4-0.02.90.1-0.01.0
Ambulatory time before self-admin4.14.25.1-2.1-2.32.0-1.62.2-2.1-2.1-1.91.8-2.2
Ambulatory time after self-admin1.01.12.3-1.5-1.11.5-0.60.9-1.2-0.2-1.11.0-0.7
Bone: tissue strength0.40.42.30.4-0.3-0.2-0.90.1-0.41.5-0.40.40.2
Total heroin consumption0.80.94.0-0.01.3-0.32.0-0.80.9-0.80.8-0.70.4
Bone: trabecular number1.42.14.51.41.9-1.32.1-1.11.5-0.11.6-1.51.3
Bone: trabecular spacing0.81.02.0-0.8-1.00.8-1.01.0-1.20.3-1.21.4-0.8
Bone: trabecular thickness0.30.41.50.60.6-0.51.2-0.10.40.20.8-0.70.6
Bone: trabecular tissue density0.50.82.21.0-0.2-1.2-1.5-0.70.51.30.5-0.30.4
Water consumed over 24 hours1.41.73.11.11.4-1.11.0-1.41.31.81.1-1.21.5
Number of responses in last shaping day0.20.20.90.20.7-0.30.9-0.10.2-0.10.00.10.1