Hub : Genes

Nptxr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Nptxr 0.27 0.11 1.3e-04 0.1 0.09 0.06 0.02 2.6e-03 3.3e-03 1.2e-02 8.6e-02
2 Adipose gene expression Nptxr 0.34 0.1 0.0e+00 0.34 0.34 0.36 0.34 2.7e-39 2.3e-39 5.5e-42 9.6e-39
3 NAcc mRNA stability Nptxr 0.02 0.01 2.8e-03 0.01 0.01 0.01 0.01 3.7e-02 6.2e-03 7.0e-03 1.1e-02
4 Liver gene expression Nptxr 0.11 0.06 2.3e-09 0.06 0.08 0.06 0.08 4.8e-07 7.5e-09 1.2e-07 7.5e-09
5 Brain mRNA stability Nptxr 0.12 0.05 2.9e-10 0.13 0.11 0.1 0.12 6.3e-12 3.1e-10 1.2e-09 3.3e-11
6 LHb mRNA stability Nptxr 0.15 0.08 5.3e-03 -0 0.08 0.02 0 3.7e-01 6.5e-03 9.5e-02 2.6e-01
7 Adipose mRNA stability Nptxr 0.07 0.03 7.8e-09 0.07 0.06 0.06 0.07 1.0e-08 3.6e-07 3.4e-07 8.8e-08
8 OFC mRNA stability Nptxr 0.31 0.13 4.8e-05 0.09 0.03 0.06 0 3.2e-03 8.4e-02 1.4e-02 2.8e-01
9 IC mRNA stability Nptxr 0.15 0.07 1.9e-04 0.05 0.06 0.07 0.06 5.2e-03 1.7e-03 8.2e-04 1.4e-03
10 Brain gene expression Nptxr 0.15 0.07 2.5e-12 0.11 0.12 0.13 0.13 2.7e-10 7.8e-11 1.9e-12 6.8e-12
11 PL mRNA stability Nptxr 0.05 0.03 1.4e-05 0.03 0.04 0.05 0.04 3.7e-04 1.2e-05 3.1e-06 4.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.10.5-0.20.2-0.30.2-0.1-0.20.1-0.1-0.1-0.50.7
Area under the delay curve3.84.46.3-2.42.5-2.32.1-1.7-2.02.4-2.4-2.3-0.1-1.8
BMI with tail0.72.64.11.6-1.71.8-1.81.31.5-1.61.61.6-0.92.0
BMI without tail0.72.15.11.7-1.51.2-1.01.01.3-1.21.22.3-1.51.8
Body weight2.310.012.93.5-3.43.5-3.43.62.3-3.23.23.50.43.4
Weight adjusted by age0.30.51.10.9-0.80.40.00.41.1-0.60.61.0-0.50.4
Bone surface0.10.20.7-0.40.6-0.60.4-0.1-0.60.2-0.2-0.8-0.10.4
Bone volume0.10.10.4-0.30.3-0.20.2-0.2-0.1-0.00.0-0.3-0.50.6
Breakpoint value in progressive ratio session0.10.10.4-0.50.4-0.1-0.20.1-0.5-0.20.2-0.6-0.30.3
Number of licking bursts0.81.32.9-1.01.0-1.31.6-1.4-0.71.1-1.1-0.2-1.0-1.7
Context. condit. distance diff. score6.78.112.13.3-3.33.5-3.02.33.1-3.23.22.50.12.1
Locomotion velocity, session 10.40.51.0-0.00.5-0.40.30.3-0.91.0-1.0-0.61.0-0.6
Locomotion distance, session 14.65.88.6-2.42.8-2.92.9-2.4-2.12.5-2.5-2.5-0.5-1.9
Locomotion velocity, session 20.20.32.1-0.20.4-0.1-0.2-0.1-0.40.2-0.2-1.40.50.5
Locomotion distance, session 25.57.711.2-3.13.3-3.22.8-2.2-3.23.1-3.1-3.00.4-1.6
Locomotion velocity, session 31.82.15.02.0-1.71.5-0.90.82.2-1.51.51.4-0.90.4
Locomotion distance, session 31.01.04.40.00.3-0.71.5-1.41.0-0.10.10.3-2.1-1.1
Stereotopy head waving bouts, day 30.50.61.70.6-0.50.8-1.11.3-0.4-0.40.40.31.10.9
Stereotopy head waving duration, day 32.42.86.01.5-1.62.0-2.42.50.3-1.31.31.01.41.9
Locomotion velocity, session 70.50.51.00.6-0.61.0-0.80.40.8-0.70.71.00.1-0.6
Locomotion distance, session 70.20.20.9-0.20.20.10.10.3-0.50.2-0.20.70.8-1.0
Stereotopy head waving bouts, day 73.64.16.12.2-2.32.4-2.11.62.5-2.42.40.9-0.12.1
Stereotopy head waving duration, day 73.34.06.42.0-2.32.3-2.21.32.5-2.32.30.7-0.42.3
Locomotion velocity, session 81.61.94.11.3-1.41.5-1.62.00.5-1.41.40.21.21.6
Locomotion distance, session 80.50.71.31.1-0.90.9-0.80.51.1-1.01.00.20.40.8
Degree of sensitization distance2.12.16.90.7-1.01.6-2.12.4-0.5-0.50.51.02.60.9
Degree of sensitization stereotypy2.72.95.31.7-1.91.9-1.71.22.3-2.02.00.3-0.22.0
Conditioned locomotion0.60.61.60.7-0.70.8-0.70.90.5-0.80.81.30.80.4
Cocaine response after cond. corrected0.30.41.7-0.20.3-0.0-0.30.7-0.70.5-0.5-0.71.30.4
Cocaine response after cond. not corrected0.20.20.9-0.20.2-0.1-0.30.6-0.50.3-0.3-0.71.00.5
Cocaine response before conditioning0.20.31.9-0.10.0-0.20.3-0.70.6-0.20.20.1-1.4-0.1
Saline control response0.60.82.71.7-1.30.9-0.60.81.3-0.60.60.8-0.1-0.2
Bone: connectivity density0.10.10.60.2-0.30.2-0.20.6-0.0-0.40.40.40.10.7
Bone: cortical apparent density0.70.92.60.9-0.80.10.6-0.71.5-0.20.21.6-1.6-0.5
Bone: cortical area0.30.41.4-0.10.10.5-0.90.8-0.70.5-0.5-0.41.20.6
Bone: cortical porosity0.70.72.50.0-0.30.8-1.31.3-0.2-0.50.5-0.71.60.4
Bone: cortical porosity1.41.55.40.3-0.51.2-1.92.0-0.4-0.60.6-0.72.30.8
Bone: cortical thickness0.61.02.4-1.01.0-0.60.4-0.7-1.11.5-1.5-0.90.3-0.8
Bone: cortical thickness1.82.14.2-1.31.8-1.41.1-1.2-1.92.1-2.1-1.20.5-0.7
Bone: cortical tissue density0.60.82.60.9-0.80.10.6-0.61.4-0.20.21.6-1.5-0.5
Condit. Reinf. active minus inactive responses0.10.10.4-0.00.2-0.10.3-0.4-0.10.3-0.30.6-0.6-0.3
Condit. Reinf. active-inactive response ratio0.30.30.90.8-0.60.7-0.3-0.00.8-0.30.30.9-0.7-0.2
Condit. Reinf. active responses0.30.41.5-0.10.1-0.40.7-0.90.10.2-0.21.1-1.20.0
Condit. Reinf. inactive responses0.40.52.1-0.20.1-0.60.9-1.00.30.0-0.01.1-1.50.2
Incentive salience index mean0.20.31.0-0.20.3-0.40.6-0.6-0.20.3-0.31.0-0.8-0.2
Condit. Reinf. lever presses0.30.42.2-0.20.3-0.40.6-0.7-0.10.0-0.01.5-1.00.2
Condit. Reinf. active minus inactive responses0.91.22.7-0.91.2-0.90.7-0.1-1.61.3-1.3-1.20.8-0.9
Condit. Reinf. active-inactive response ratio0.40.41.6-0.40.5-0.2-0.10.6-1.30.7-0.7-0.71.00.1
Condit. Reinf. active responses0.70.92.3-0.71.0-0.40.20.2-1.31.0-1.0-1.51.2-1.0
Condit. Reinf. inactive responses0.40.51.4-0.70.9-0.30.2-0.3-0.60.6-0.6-1.20.5-1.1
Condit. Reinf. lever presses0.30.40.7-0.60.8-0.80.7-0.8-0.80.4-0.4-0.6-0.0-0.4
Condit. Reinf. lever reinforcers received0.60.92.3-0.60.9-0.40.10.3-1.30.9-0.9-1.31.5-0.9
Conditioned reinforcement - actives1.72.84.5-2.02.1-1.61.5-1.1-2.01.9-1.9-1.80.4-1.3
Conditioned reinforcement - inactives2.84.28.8-2.62.5-2.31.9-1.1-3.02.1-2.1-1.50.1-1.6
Conditioned locomotion1.52.05.0-1.41.6-0.90.1-0.1-2.21.8-1.8-1.71.5-0.4
Patch foraging indifference point 0 sec0.10.31.60.6-0.40.1-0.30.5-0.20.1-0.11.30.40.4
Patch foraging indifference point AUC2.23.24.9-2.12.0-2.02.2-1.5-1.82.0-2.0-0.9-0.5-1.9
Delay disc. indifference point, 0s delay0.20.20.60.2-0.00.3-0.80.7-0.50.2-0.2-0.20.50.2
Delay disc. indifference point, 16s delay4.65.17.3-2.72.6-2.52.4-1.8-2.02.5-2.5-2.60.2-1.8
Delay disc. indifference point, 2s delay5.46.012.9-2.73.0-2.41.9-2.2-2.22.7-2.7-3.6-0.5-1.5
Delay disc. indifference point, 24s delay0.91.02.0-1.11.1-1.21.4-0.3-1.11.0-1.0-0.20.5-1.1
Delay disc. indifference point, 4s delay2.12.24.0-1.51.7-1.51.3-1.1-1.51.8-1.8-2.0-0.0-1.2
Delay disc. indifference point, 8s delay2.52.94.2-2.02.0-2.02.1-1.5-1.72.0-2.0-1.1-0.3-1.4
Indifference point function ln k2.44.26.02.5-2.42.4-2.32.02.2-2.32.31.30.51.8
Indifference point function log k2.44.26.02.5-2.42.4-2.32.02.2-2.32.31.30.51.8
Patch foraging total patch changes 0 sec0.10.21.00.3-0.1-0.30.10.1-0.40.5-0.51.0-0.00.1
Patch foraging total patch changes 12 sec0.40.51.2-0.40.8-0.50.2-0.2-1.10.9-0.9-0.31.0-0.6
Patch foraging total patch changes 18 sec0.81.24.3-1.21.2-1.10.70.1-2.11.3-1.3-0.20.6-0.4
Patch foraging total patch changes 24 sec0.61.02.1-1.00.8-1.01.0-0.8-1.01.1-1.10.4-0.8-1.5
Patch foraging total patch changes 6 sec1.11.63.4-1.21.4-1.51.2-0.6-1.91.8-1.8-0.00.1-0.7
Patch foraging time to switch 0 sec0.20.41.9-0.30.40.1-0.70.1-0.40.1-0.1-1.41.00.5
Patch foraging water rate 0 sec0.30.75.40.8-0.90.3-0.00.80.2-0.10.12.3-0.20.4
Patch foraging water rate 12 sec0.20.41.60.8-0.90.2-0.00.20.8-0.20.21.3-0.70.2
Patch foraging water rate 18 sec0.30.42.70.5-0.7-0.10.30.70.30.1-0.11.6-0.10.5
Patch foraging water rate 24 sec2.33.24.72.2-2.21.7-1.62.11.5-1.81.82.00.11.6
Patch foraging water rate 6 sec0.71.04.31.0-1.10.20.30.31.2-0.90.92.1-1.10.1
Seeking ratio, delayed vs. immediate footshock0.30.41.3-0.40.5-0.70.8-1.00.10.2-0.2-0.4-1.1-0.4
Distance traveled before self-admin1.72.23.3-1.71.7-1.51.0-1.2-1.61.8-1.8-1.80.9-0.7
Distance traveled after self-admin0.50.72.4-0.60.7-0.60.20.7-1.50.4-0.40.21.60.6
Extensor digitorum longus weight0.51.93.3-1.21.2-1.71.6-1.8-0.61.6-1.6-1.4-1.2-0.7
Bone: elastic displacement0.30.40.60.7-0.70.6-0.40.70.6-0.40.40.80.80.0
Bone: elastic work1.11.45.70.6-0.61.1-1.61.8-0.3-0.10.10.12.41.3
Bone: endosteal estimation0.61.43.50.7-0.51.1-1.51.9-0.3-1.01.0-0.11.81.7
Bone: endosteal perimeter0.81.83.70.9-0.81.6-1.91.80.3-1.31.3-0.11.41.7
Epididymis fat weight2.89.616.33.3-3.24.0-4.03.32.4-3.33.32.31.02.6
Delta time in closed arm before/after self-admin0.70.71.5-0.80.9-0.50.4-0.4-1.01.2-1.2-0.7-0.4-0.9
Delta time in open arm before/after self-admin0.10.10.2-0.20.2-0.40.4-0.1-0.10.2-0.2-0.40.50.2
Diff in mean of infusions in LGA sessions0.10.10.30.10.10.3-0.30.6-0.3-0.50.50.30.10.3
Delay discount exponential model param3.94.46.32.4-2.52.3-2.21.72.0-2.32.32.30.11.7
Extinction: sum of active levers before priming0.91.04.4-1.41.4-0.50.1-0.2-1.20.4-0.4-2.1-0.1-0.6
Active lever presses in extinction session 60.20.20.6-0.20.40.2-0.4-0.2-0.2-0.30.3-0.6-0.2-0.8
Bone: final force0.50.83.3-0.20.50.3-0.90.9-1.10.5-0.5-0.81.81.1
Bone: final moment0.60.93.6-0.20.40.4-0.91.1-1.20.5-0.5-0.81.91.2
Food consumed during 24 hour testing period0.20.30.9-0.10.10.4-0.91.0-0.90.2-0.2-0.50.70.1
Glucose0.40.61.20.3-0.40.7-0.91.1-0.1-0.80.81.01.00.7
Heart weight2.53.98.71.8-1.92.1-2.52.90.6-1.61.61.41.72.5
Delay discount hyperbolic model param4.24.76.62.4-2.62.4-2.21.92.0-2.42.42.50.31.7
Intermittent access intake day 1-15 change0.10.21.60.2-0.2-0.20.2-0.30.2-0.20.20.3-0.61.3
Intermittent access intake escalation0.10.31.50.1-0.2-0.30.5-0.50.3-0.10.10.3-0.71.2
Intermittent access intake escalation 20.20.20.50.4-0.3-0.20.3-0.60.30.0-0.00.7-0.70.6
Intermitt. access day 1 inactive lever presses0.20.94.7-0.3-0.00.4-0.81.4-0.9-0.50.50.52.20.6
Intermitt. access day 15 inactive lever presses0.20.51.8-0.90.9-0.90.8-0.2-1.30.4-0.4-0.20.2-0.3
Intermitt. access escalation Index0.50.75.8-0.30.2-0.60.7-0.80.2-0.30.3-0.3-2.4-0.3
Intermittent access day 1 total infusions2.33.77.6-2.62.4-1.61.0-0.5-2.71.9-1.9-2.81.2-1.1
Intermittent access day 15 total infusions1.72.64.0-2.01.9-1.81.6-1.2-1.81.7-1.7-2.00.3-0.2
Intermittent access terminal intake (last 3 days)2.02.64.2-2.02.0-1.71.5-1.2-1.91.7-1.7-2.10.3-0.6
Intermittent access total infusions4.55.39.5-3.02.9-2.11.5-1.1-3.12.5-2.5-3.01.0-1.4
Intermittent access day 1 locomotion1.72.25.2-2.01.9-1.40.8-0.6-2.31.5-1.5-1.60.4-0.8
Intermittent access day 15 total locomotion0.40.82.7-1.21.1-0.60.1-0.1-1.60.7-0.7-0.91.0-0.4
Intermittent access total locomotion0.80.94.1-1.21.1-0.60.00.2-2.00.8-0.8-0.61.0-0.4
Intermittent access standard deviation0.91.99.8-1.21.1-0.3-0.40.8-2.01.0-1.0-0.93.10.3
Left kidney weight4.621.345.64.2-4.35.9-6.36.82.2-4.04.01.84.84.0
Right kidney weight6.629.957.85.1-5.16.8-7.37.62.5-4.94.92.95.45.1
Cocaine induced anxiety0.50.71.50.8-0.81.2-1.20.70.4-0.90.90.40.40.8
Post-drug Anxiety1.31.42.41.4-1.51.2-0.80.61.3-1.31.31.5-0.71.0
Baseline Anxiety0.50.61.7-0.20.5-1.01.3-1.00.00.7-0.70.1-1.1-0.8
Tail length0.62.27.51.9-1.71.0-0.61.41.3-1.41.42.7-0.60.8
Length with tail1.77.310.63.3-3.12.9-2.53.22.2-2.72.73.30.92.1
Length without tail2.27.014.92.6-2.73.1-3.43.91.1-2.52.51.82.32.3
Times rat made contact with spout0.40.51.5-0.20.4-0.40.6-0.1-0.50.5-0.51.2-1.2-1.1
Lifetime Intake4.96.011.2-3.13.1-1.91.2-1.0-3.42.7-2.7-3.11.5-1.6
Liver weight, left0.61.02.31.3-1.11.3-1.00.21.5-1.11.10.7-0.1-0.2
Liver weight, right5.69.714.63.7-3.63.5-2.92.33.7-3.83.82.8-1.21.8
Locomotor activity1.42.14.32.1-1.61.7-1.81.80.9-1.11.10.90.51.7
Locomotor testing distance0.10.10.50.7-0.2-0.00.10.00.20.1-0.10.6-0.50.3
Locomotor testing rearing0.40.82.11.1-0.71.2-1.41.00.4-0.50.50.10.80.7
Locomotion in novel chamber0.91.16.00.00.0-0.81.3-1.61.1-0.30.30.5-2.5-0.5
Locomotion in novel chamber post-restriction0.91.54.7-1.01.2-1.11.2-1.9-0.20.6-0.6-1.0-2.2-1.1
Fecal boli incidents, locomotor time 10.81.13.1-1.11.1-1.00.6-0.2-1.81.3-1.3-0.11.2-0.7
Change in fecal boli incidents, locomotor task1.31.32.31.5-1.31.2-0.60.81.5-1.21.21.3-0.40.7
Time >=10cm from walls, locomotor time 10.70.72.70.4-0.50.8-1.11.2-0.4-0.50.50.31.70.8
Bouts of movement, locomotor time 10.40.51.00.5-0.50.9-0.80.80.4-1.01.00.50.0-0.5
Total resting periods, locomotor time 10.20.20.50.1-0.10.5-0.50.6-0.2-0.50.50.30.4-0.7
Rest time, locomotor task time 10.30.41.0-0.3-0.10.6-0.80.9-0.6-0.40.40.51.00.3
Distance moved, locomotor task time 10.50.82.31.5-1.00.8-0.60.31.4-0.90.90.5-0.50.8
Vertical activity count, locomotor time 10.61.44.61.7-1.41.0-0.81.00.9-1.11.12.1-0.50.6
Time >=10cm from walls, locomotor time 20.40.52.20.4-0.60.4-0.40.90.1-0.80.81.50.70.5
Bouts of movement, locomotor time 20.30.51.5-0.60.6-0.20.0-1.0-0.10.0-0.0-1.2-1.0-1.0
Total resting periods, locomotor time 20.50.93.0-1.01.1-0.60.3-1.1-0.60.5-0.5-1.7-0.8-1.1
Rest time, locomotor task time 20.30.40.9-0.90.8-0.60.5-0.2-1.00.6-0.6-0.50.60.2
Distance moved, locomotor task time 21.11.32.21.5-1.21.2-1.10.91.3-1.21.21.2-0.00.9
Vertical activity count, locomotor time 21.21.64.21.5-1.21.1-1.01.30.7-1.41.42.00.21.4
Light reinforcement 10.00.10.2-0.20.3-0.30.1-0.4-0.40.5-0.5-0.50.1-0.1
Light reinforcement 20.50.71.30.7-0.81.1-1.10.21.1-1.11.1-0.0-0.30.8
Bone: marrow area0.71.53.70.7-0.51.1-1.51.9-0.3-1.01.0-0.01.81.8
Bone: maximum diameter1.22.25.30.9-0.81.7-2.32.3-0.2-0.70.70.02.21.9
Bone: maximum force0.71.34.3-0.30.60.3-1.01.2-1.60.7-0.7-1.02.11.3
Bone: maximum moment0.81.44.6-0.30.50.4-1.11.4-1.60.7-0.7-1.02.11.4
Mean time between licks in bursts0.41.12.0-0.70.8-1.21.1-1.3-0.21.3-1.3-1.4-0.5-0.8
Mean num. licks in bursts0.71.01.81.1-1.01.3-1.31.30.6-1.01.01.10.10.8
Cd content in liver0.30.30.91.0-0.60.4-0.20.40.5-0.60.60.3-0.70.8
Co content in liver1.01.11.8-0.81.1-1.21.1-0.8-1.41.3-1.3-0.4-0.0-1.3
Cu content in liver3.33.97.6-2.02.1-2.72.8-2.7-1.21.8-1.8-0.7-1.9-0.7
Fe content in liver3.44.210.21.8-1.81.8-2.22.80.6-1.81.81.12.23.2
K content in liver0.20.20.5-0.60.4-0.60.7-0.3-0.10.4-0.4-0.10.1-0.5
Mg content in liver0.20.20.5-0.70.5-0.50.5-0.2-0.50.2-0.2-0.10.10.3
Mn content in liver0.10.10.4-0.40.3-0.10.3-0.60.4-0.20.2-0.5-0.5-0.3
Na content in liver0.10.10.5-0.10.0-0.40.4-0.1-0.10.0-0.00.60.30.7
Rb content in liver0.60.71.5-0.91.0-0.80.6-0.4-1.21.2-1.2-0.40.6-0.6
Se content in liver0.60.73.00.5-0.5-0.10.5-0.51.2-0.30.30.1-1.21.7
Sr content in liver2.32.06.4-1.31.2-1.72.0-2.5-0.21.0-1.0-0.4-2.0-0.3
Zn content in liver0.10.10.20.1-0.0-0.20.4-0.10.10.0-0.00.3-0.40.4
Bone: minimum diameter0.20.41.3-0.20.20.5-1.00.9-0.7-0.00.0-0.71.10.6
Time in familiar zone, hab. session 10.30.20.5-0.70.7-0.50.6-0.2-0.70.5-0.5-0.20.1-0.2
Time in novel zone, hab. session 11.41.42.21.5-1.41.2-1.41.30.9-1.21.20.70.41.1
Total zone transitions, hab. session 11.62.35.9-0.80.9-1.82.4-2.20.31.0-1.0-0.6-2.2-1.5
Total locomotion distance, hab. session 10.50.72.10.1-0.0-0.71.4-1.20.8-0.10.10.3-1.5-1.2
Locomotion velocity, hab. session 10.60.92.7-0.40.4-1.11.6-1.50.30.2-0.2-0.0-1.4-1.0
Time in familiar zone, hab. session 20.40.41.40.3-0.30.00.4-0.81.1-0.40.40.8-1.2-0.1
Time in novel zone, hab. session 20.40.41.4-0.30.3-0.1-0.40.9-1.20.3-0.3-0.71.00.1
Total zone transitions, hab. session 21.51.93.0-1.51.6-1.71.7-1.4-1.61.6-1.6-0.50.3-0.8
Total locomotion distance, hab. session 21.41.82.6-1.41.5-1.61.4-1.0-1.61.5-1.5-1.11.0-1.0
Locomotion velocity, hab. session 21.72.33.4-1.61.7-1.81.7-1.2-1.81.7-1.7-1.00.9-1.1
Novel to familiar place preference ratio2.83.15.02.2-2.11.7-1.51.71.5-2.12.11.1-0.52.0
Novelty place preference3.84.16.42.5-2.42.0-1.71.81.9-2.42.41.4-0.72.2
Time in novel zone, NPP test4.54.87.42.7-2.62.1-1.92.02.0-2.62.61.6-0.82.5
Total zone transitions, NPP test2.02.97.6-1.41.6-2.32.8-2.1-0.81.6-1.6-0.8-0.8-1.8
Total locomotion distance, NPP test1.01.33.0-0.91.1-1.51.7-1.1-0.81.1-1.1-0.70.1-1.4
Locomotion velocity, NPP test1.62.24.2-1.21.5-1.82.0-1.6-0.91.5-1.5-0.9-0.1-2.0
Intraocular pressure0.30.40.90.7-0.60.9-0.90.70.4-0.80.8-0.00.5-0.2
Delta distance traveled before/after self-admin2.32.44.91.5-1.51.4-1.32.20.5-1.71.72.20.81.4
Delta ambulatory time before/after self-admin1.31.64.11.3-1.11.2-1.12.00.2-1.11.11.71.31.2
Parametrial fat weight1.33.18.02.1-1.91.4-0.90.72.1-1.91.92.8-1.90.6
Pavlov. Cond. lever latency0.10.10.50.4-0.30.3-0.30.30.10.1-0.10.00.70.1
Pavlov. Cond. magazine entry latency1.51.93.5-1.91.7-1.51.4-1.3-1.41.3-1.3-1.4-0.3-1.0
Pavlov. Cond. change in total contacts3.03.25.7-2.42.2-1.91.6-1.6-2.01.9-1.9-1.8-0.4-1.1
Pavlov. Cond. index score0.60.81.7-1.31.2-0.90.8-0.7-1.10.7-0.7-0.7-0.2-0.7
Pavlov. Cond. latency score0.30.40.9-0.90.8-0.70.6-0.5-0.80.4-0.4-0.5-0.3-0.4
Pavlov. Cond. lever contacts0.50.61.2-1.10.9-0.90.9-0.8-0.70.5-0.5-0.3-0.9-0.6
Pavlov. Cond. magazine entry number1.82.33.82.0-1.81.6-1.51.61.4-1.51.51.30.41.5
Pavlov. Cond. intertrial magazine entries0.20.20.70.00.1-0.50.6-0.0-0.40.7-0.70.8-0.40.4
Pavlov. Cond. lever-magazine prob. diff.0.70.81.7-1.31.2-1.00.9-0.9-1.00.7-0.7-0.7-0.5-0.8
Pavlov. Cond. response bias1.31.63.2-1.81.6-1.41.2-1.3-1.31.2-1.2-1.0-0.4-1.2
Pavlov. Cond. lever latency0.00.10.20.0-0.00.20.0-0.10.30.1-0.1-0.3-0.5-0.2
Pavlov. Cond. magazine entry latency1.61.93.4-1.51.5-1.71.3-0.8-1.81.8-1.8-0.70.6-0.8
Pavlov. Cond. change in total contacts0.71.15.80.2-0.00.2-0.81.8-1.30.2-0.20.72.40.7
Pavlov. Cond. index score0.40.51.3-0.60.7-0.80.6-0.0-1.10.9-0.90.11.0-0.4
Pavlov. Cond. latency score0.60.81.6-0.80.8-1.00.8-0.1-1.31.1-1.10.11.0-0.7
Pavlov. Cond. lever contacts0.00.10.30.1-0.1-0.2-0.00.2-0.3-0.10.10.60.40.3
Pavlov. Cond. magazine entry number0.40.50.80.5-0.60.8-0.70.10.9-0.90.9-0.1-0.80.5
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.20.30.4-0.50.4-0.4-0.40.40.20.20.1
Pavlov. Cond. lever-magazine prob. diff.0.30.51.1-0.50.6-0.80.6-0.0-1.00.9-0.90.10.9-0.4
Pavlov. Cond. response bias0.20.31.0-0.50.6-0.60.3-0.0-1.00.5-0.5-0.00.90.1
Time in closed arm before self-admin0.40.51.2-0.80.6-1.10.8-0.8-0.70.7-0.7-0.10.0-0.1
Time in closed arm after self-admin0.10.10.90.0-0.20.3-0.40.4-0.40.1-0.10.9-0.3-0.3
Time in open arm before self-admin0.20.20.70.5-0.40.30.1-0.00.8-0.30.30.7-0.30.4
Time in open arm after self-admin0.10.10.70.2-0.1-0.20.6-0.60.8-0.20.20.1-0.30.2
Bone: periosteal estimation0.61.23.40.4-0.21.0-1.61.7-0.5-0.40.4-0.41.81.5
Bone: periosteal perimeter1.52.55.91.1-1.12.0-2.42.40.2-1.11.10.32.11.8
Bone: post-yield work0.71.03.6-1.11.3-0.90.5-0.2-1.91.0-1.0-1.20.40.7
Progressive ratio test 1 active lever presses3.03.87.1-2.52.6-1.71.2-0.7-2.72.0-2.0-2.60.6-1.0
Progressive ratio test 1 breakpoint2.93.66.5-2.42.5-1.71.2-0.7-2.52.0-2.0-2.50.6-1.0
Progressive ratio test 1 inactive lever presses3.04.39.7-2.82.6-1.81.0-0.7-3.12.3-2.3-2.41.2-1.1
Progressive ratio test 2 active lever presses3.03.56.6-2.52.4-1.71.4-0.7-2.61.9-1.9-2.10.5-1.6
Progressive ratio test 2 breakpoint3.54.06.8-2.62.6-1.81.5-0.9-2.62.1-2.1-2.30.4-1.7
Progressive ratio test 2 inactive lever presses2.33.76.6-2.62.3-2.22.0-1.5-2.21.8-1.8-1.7-0.5-1.7
Incentive Sensitization - Responses0.50.71.8-1.00.9-0.91.0-0.5-0.70.7-0.7-0.6-0.2-1.3
Incentive Sensitization - Breakpoint0.50.61.6-1.00.8-0.80.8-0.4-0.80.6-0.6-0.6-0.1-1.3
Sum of active levers in priming session hrs 5-60.30.21.00.2-0.10.2-0.20.10.1-1.01.00.2-0.50.5
Progressive ratio0.10.10.4-0.20.1-0.2-0.00.4-0.60.4-0.4-0.30.30.4
Food seeking constrained by brief footshock0.20.20.7-0.20.5-0.1-0.2-0.1-0.60.7-0.7-0.80.5-0.1
Seeking ratio, punishment vs. effort0.10.10.2-0.30.40.0-0.1-0.2-0.30.3-0.3-0.30.3-0.3
Retroperitoneal fat weight3.113.323.33.9-3.84.8-4.84.12.8-3.73.72.50.93.1
Reaction time number correct0.40.94.5-0.20.0-0.40.9-1.01.1-0.60.6-0.1-2.1-1.0
Reaction time mean minus median0.00.10.6-0.0-0.10.1-0.10.3-0.0-0.30.3-0.00.50.8
Reaction time mean minus median AUC0.20.61.00.7-0.80.9-1.00.80.6-1.01.00.60.50.8
Reaction time num false alarms0.10.20.50.6-0.70.3-0.40.60.5-0.30.30.3-0.00.1
Reaction time num false alarms AUC0.10.10.50.6-0.70.3-0.20.40.6-0.20.20.1-0.1-0.2
Reaction time trials correct on left0.40.94.5-0.20.0-0.40.9-1.01.1-0.60.6-0.1-2.1-1.0
Reaction time trials on left0.50.94.7-0.30.1-0.51.0-1.01.1-0.50.5-0.2-2.2-1.1
Reaction time mean0.20.41.30.3-0.40.3-0.40.60.2-0.70.70.40.91.1
Reaction time mean AUC0.20.30.90.2-0.40.3-0.30.50.2-0.60.60.30.61.0
Median of all reaction times0.20.31.00.2-0.30.2-0.30.40.2-0.50.50.20.91.0
Reaction time omissions1.11.64.9-1.71.4-1.41.3-1.1-0.81.0-1.0-2.2-0.1-0.6
Reaction time false alarm rate0.20.20.50.6-0.70.4-0.60.70.20.0-0.00.20.60.5
Reaction time premature initiation rate0.50.72.7-0.80.4-0.2-0.51.1-1.50.3-0.3-0.51.60.8
Reaction time premature initiations0.10.20.6-0.60.2-0.1-0.20.8-0.8-0.20.2-0.30.60.3
Std. dev. reaction times0.40.81.80.6-0.90.8-0.81.30.5-1.11.10.60.71.4
Reaction time trials completed0.50.94.7-0.30.1-0.51.0-1.01.1-0.50.5-0.2-2.2-1.1
Reaction time trials AUC0.40.73.8-0.1-0.1-0.20.7-0.71.1-0.60.6-0.1-2.0-0.8
Run reversals in cocaine runway, females0.60.61.80.8-1.10.4-0.10.41.0-0.80.81.3-0.10.2
Run reversals in cocaine runway, males0.10.10.30.20.10.3-0.00.10.10.6-0.6-0.40.6-0.5
Latency to leave start box in cocaine runway0.40.40.70.3-0.50.7-0.80.40.9-0.70.7-0.90.30.6
Latency to leave start box in cocaine runway, F0.20.21.2-0.40.4-0.20.1-0.30.10.6-0.6-1.10.50.2
Latency to leave start box in cocaine runway, M2.12.04.81.1-1.41.5-1.51.21.4-2.22.20.20.11.0
Std. dev. time between licks in bursts0.40.51.3-0.40.4-0.90.8-0.3-0.61.1-1.1-0.20.4-0.7
Total sessions with >9 infusions1.82.24.9-1.71.7-0.2-0.60.6-2.21.5-1.5-2.12.0-0.6
Short access day 1 total inactive lever presses1.82.310.1-1.11.3-0.7-0.10.9-2.61.5-1.5-0.53.2-0.1
Short access day 10 total inactive lever presses0.71.74.61.0-1.21.2-1.11.60.3-1.41.42.11.11.0
Short access day 1 total infusions1.01.33.2-1.31.2-0.4-0.10.5-1.81.2-1.2-0.91.8-0.7
Short access day 10 total infusions1.31.74.1-1.61.5-0.4-0.30.4-2.01.2-1.2-2.01.60.1
Short access total infusions2.73.47.9-2.42.3-0.90.00.1-2.81.9-1.9-2.61.8-1.0
Short access day 1 locomotion0.50.62.8-0.70.7-0.2-0.30.6-1.20.8-0.8-0.31.7-0.0
Short access day 10 total locomotion0.40.83.0-1.30.8-0.60.10.7-1.70.6-0.60.11.10.4
Short access total locomotion0.81.03.1-1.11.0-0.2-0.50.7-1.81.0-1.0-0.61.70.1
One hour access (0.3 mA shock)6.47.311.4-3.43.3-2.82.4-2.7-2.72.9-2.9-3.0-0.9-1.9
Compulsive drug intake0.60.71.8-0.80.6-0.91.4-1.0-0.30.4-0.40.2-1.1-1.1
One hour access (shock baseline)1.52.34.7-1.81.8-1.40.9-1.4-1.61.8-1.8-2.20.0-0.8
Social response proportion0.40.52.5-0.50.1-0.1-0.60.6-0.30.3-0.3-1.60.61.2
Social responses0.81.12.2-0.91.0-1.10.8-0.5-1.11.5-1.5-1.40.4-0.5
Social time2.63.65.4-2.02.3-2.21.8-1.8-2.02.3-2.3-1.70.6-1.1
Soleus weight0.41.23.2-1.00.9-0.91.1-0.0-1.31.2-1.21.10.7-1.8
Bone: stiffness0.61.02.80.20.10.6-1.21.4-1.10.2-0.2-0.11.61.7
Tibialis anterior weight2.06.89.7-2.62.8-3.12.9-2.9-2.13.1-3.1-2.0-1.5-2.2
Time to tail flick, vehicle, before self-admin0.10.10.3-0.1-0.0-0.1-0.10.5-0.4-0.40.4-0.3-0.60.5
Time to tail flick, vehicle, after self-admin0.50.63.30.9-0.90.3-0.10.80.5-0.70.71.8-0.3-0.3
Time to tail flick, test, before self-admin0.60.62.0-0.50.4-0.10.2-0.7-0.01.0-1.0-0.7-0.9-1.4
Time to tail flick, test, after self-admin0.30.30.9-0.00.0-0.30.5-0.60.4-0.10.10.7-0.9-0.8
Delta time to tail flick, vehicle, before/after SA0.30.31.7-0.00.1-0.1-0.10.1-0.30.5-0.50.21.3-0.6
Delta time to tail flick, test, before/after SA0.50.51.20.3-0.2-0.70.9-0.70.4-0.60.61.1-1.1-0.2
Tibia length0.30.83.10.3-0.20.7-0.81.4-0.4-0.50.5-0.01.81.3
Ambulatory time before self-admin1.01.52.1-1.41.4-1.41.2-1.1-1.21.4-1.4-1.20.2-0.8
Ambulatory time after self-admin0.30.41.0-0.40.5-0.90.80.3-1.00.4-0.40.40.80.2
Bone: tissue strength0.40.40.60.4-0.70.8-0.70.80.5-0.60.60.40.70.4
Total heroin consumption0.91.12.8-1.11.4-0.80.5-0.8-1.21.0-1.0-1.70.1-0.9
Bone: trabecular number0.20.30.70.5-0.50.4-0.20.10.8-0.60.60.5-0.70.4
Bone: trabecular spacing0.50.63.4-0.20.50.1-0.40.8-1.30.3-0.30.31.90.1
Bone: trabecular thickness0.40.52.3-0.0-0.30.3-0.1-0.41.0-0.60.60.1-1.50.7
Bone: trabecular tissue density0.30.41.80.6-0.5-0.40.4-0.30.40.2-0.21.2-1.30.6
Water consumed over 24 hours0.20.30.8-0.10.2-0.30.30.3-0.70.6-0.60.6-0.3-0.9
Number of responses in last shaping day4.75.19.1-3.02.8-2.11.2-0.9-3.02.6-2.6-3.01.1-0.6