Hub : Genes

Nptxr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Nptxr 0.1 0.05 3.4e-09 0.06 0.07 0.07 0.07 6.1e-07 1.0e-08 2.7e-08 1.5e-08
2 IL mRNA stability Nptxr 0.27 0.11 4.3e-05 0.12 0.1 0.06 0.1 1.0e-03 2.0e-03 1.4e-02 2.2e-03
3 Adipose mRNA stability Nptxr 0.07 0.03 7.6e-09 0.08 0.06 0.06 0.07 2.8e-09 2.7e-07 2.3e-07 5.4e-08
4 OFC mRNA stability Nptxr 0.27 0.13 4.1e-04 0.07 0.02 0.06 0.01 8.4e-03 9.1e-02 1.6e-02 2.3e-01
5 Adipose gene expression Nptxr 0.34 0.1 0.0e+00 0.34 0.34 0.36 0.34 1.3e-38 1.8e-39 4.1e-42 4.2e-39
6 PL mRNA stability Nptxr 0.06 0.03 4.4e-06 0.04 0.05 0.05 0.05 2.2e-05 2.1e-06 2.7e-06 4.1e-06
7 LHb mRNA stability Nptxr 0.16 0.09 4.3e-03 0.06 0.1 0.05 0.09 1.8e-02 2.1e-03 2.9e-02 3.7e-03
8 Brain mRNA stability Nptxr 0.13 0.06 1.1e-10 0.12 0.12 0.13 0.12 2.4e-11 3.2e-11 4.2e-12 2.4e-11
9 Brain gene expression Nptxr 0.16 0.07 1.8e-12 0.09 0.14 0.12 0.13 1.2e-08 4.1e-13 1.8e-11 2.9e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.00.00.20.2-0.1-0.2-0.00.1-0.00.0-0.1
Area under the delay curve4.14.36.42.22.5-2.32.3-2.5-2.3-1.90.61.3
BMI with tail0.10.41.4-1.1-0.50.5-0.30.61.20.3-0.4-0.1
BMI without tail0.00.10.60.10.2-0.20.2-0.10.4-0.00.7-0.2
Body weight1.56.310.6-3.3-3.02.4-2.72.83.01.5-2.2-0.8
Weight adjusted by age0.60.71.6-0.1-1.00.7-0.60.70.61.30.6-1.2
Bone surface0.10.10.20.30.4-0.40.3-0.4-0.2-0.4-0.40.3
Bone volume0.00.00.10.10.20.0-0.2-0.10.00.00.3-0.2
Breakpoint value in progressive ratio session0.20.20.50.30.6-0.30.2-0.5-0.4-0.7-0.30.5
Number of licking bursts0.81.02.01.40.8-0.80.9-1.1-1.3-0.51.1-0.1
Context. condit. distance diff. score6.47.811.1-3.0-3.13.3-3.13.02.82.9-0.1-2.2
Locomotion velocity, session 10.90.91.80.40.5-1.21.4-1.0-0.6-1.0-1.21.0
Locomotion distance, session 15.16.611.03.02.8-3.02.9-3.3-2.8-2.00.71.3
Locomotion velocity, session 20.20.20.4-0.10.4-0.40.5-0.60.3-0.4-0.30.6
Locomotion distance, session 26.28.712.82.83.3-3.63.4-3.6-2.8-3.00.02.4
Locomotion velocity, session 32.32.65.3-0.9-1.81.6-1.51.51.22.31.0-2.2
Locomotion distance, session 31.51.76.91.50.1-0.0-0.1-0.5-1.21.02.6-1.8
Stereotopy head waving bouts, day 30.70.83.8-1.2-0.60.3-0.40.50.9-0.3-1.90.8
Stereotopy head waving duration, day 32.73.27.4-2.5-1.61.4-1.41.72.30.5-2.70.4
Locomotion velocity, session 70.40.41.1-0.8-0.61.0-0.60.50.50.7-0.2-0.3
Locomotion distance, session 70.20.30.70.10.5-0.30.4-0.6-0.7-0.7-0.50.8
Stereotopy head waving bouts, day 74.24.77.6-2.4-2.42.4-2.22.32.82.2-0.5-1.5
Stereotopy head waving duration, day 74.35.28.1-2.2-2.42.5-2.32.52.92.60.3-2.0
Locomotion velocity, session 80.81.02.3-1.5-1.01.0-0.90.71.30.4-1.00.2
Locomotion distance, session 80.40.61.2-0.8-0.80.7-0.70.50.91.10.3-0.8
Degree of sensitization distance2.12.17.6-2.1-0.50.6-0.40.81.4-0.7-2.81.8
Degree of sensitization stereotypy3.23.55.5-1.6-2.02.0-1.81.92.32.40.6-1.8
Conditioned locomotion0.30.30.6-0.7-0.70.6-0.50.60.70.6-0.5-0.2
Cocaine response after cond. corrected0.40.52.0-0.20.3-0.40.6-0.40.1-0.7-1.41.0
Cocaine response after cond. not corrected0.20.20.9-0.20.2-0.20.3-0.20.3-0.5-1.00.7
Cocaine response before conditioning0.20.31.20.2-0.20.3-0.40.2-0.00.51.1-0.8
Saline control response0.91.22.4-0.6-1.50.9-0.71.21.01.50.7-1.4
Bone: connectivity density0.10.10.6-0.2-0.20.2-0.40.20.20.0-0.8-0.0
Bone: cortical apparent density0.81.13.50.6-0.60.3-0.10.5-0.41.31.8-1.9
Bone: cortical area0.20.30.9-0.80.0-0.10.4-0.10.5-0.6-0.90.8
Bone: cortical porosity1.01.13.9-1.4-0.30.6-0.50.61.3-0.3-2.01.2
Bone: cortical porosity1.61.76.0-1.8-0.40.5-0.30.51.5-0.7-2.51.7
Bone: cortical thickness0.71.12.40.51.1-1.21.6-1.2-1.0-1.20.00.8
Bone: cortical thickness2.02.33.31.21.6-1.81.8-1.8-1.6-1.70.11.2
Bone: cortical tissue density0.81.03.30.5-0.70.4-0.20.5-0.31.31.7-1.8
Condit. Reinf. active minus inactive responses0.10.10.30.2-0.1-0.40.4-0.2-0.5-0.10.5-0.2
Condit. Reinf. active-inactive response ratio0.40.51.2-0.4-0.80.5-0.40.60.20.81.1-0.9
Condit. Reinf. active responses0.30.31.30.6-0.0-0.50.4-0.0-0.60.21.2-0.7
Condit. Reinf. inactive responses0.30.41.20.90.2-0.40.20.1-0.70.31.1-0.9
Incentive salience index mean0.20.20.50.50.1-0.50.5-0.3-0.7-0.20.6-0.2
Condit. Reinf. lever presses0.10.10.40.50.2-0.40.3-0.3-0.6-0.20.4-0.2
Condit. Reinf. active minus inactive responses1.21.52.60.71.1-1.31.3-1.4-1.2-1.6-0.31.5
Condit. Reinf. active-inactive response ratio0.70.72.0-0.10.5-0.80.8-0.8-0.5-1.3-0.61.4
Condit. Reinf. active responses0.60.92.10.10.8-0.80.9-1.0-0.8-1.3-0.71.5
Condit. Reinf. inactive responses0.20.20.40.20.6-0.20.3-0.7-0.6-0.5-0.20.6
Condit. Reinf. lever presses0.60.81.30.91.0-0.70.5-0.8-1.0-0.81.20.6
Condit. Reinf. lever reinforcers received0.60.82.40.10.8-0.80.8-0.8-0.7-1.3-0.71.5
Conditioned reinforcement - actives2.12.13.21.41.6-1.41.6-1.7-1.8-1.40.51.1
Conditioned reinforcement - inactives1.92.13.81.51.7-1.11.4-1.5-1.9-1.9-0.21.3
Conditioned locomotion1.41.73.10.10.8-1.61.6-1.3-0.6-1.8-1.21.7
Patch foraging indifference point 0 sec0.10.10.4-0.1-0.3-0.40.20.40.3-0.2-0.70.2
Patch foraging indifference point AUC2.83.25.71.91.8-1.82.0-2.1-2.4-1.80.41.2
Delay disc. indifference point, 0s delay0.40.41.1-0.70.1-0.10.30.10.4-0.8-1.01.1
Delay disc. indifference point, 16s delay5.35.37.72.62.7-2.72.6-2.8-2.5-2.00.61.4
Delay disc. indifference point, 2s delay4.65.19.11.83.0-2.52.6-2.9-2.1-2.30.11.8
Delay disc. indifference point, 24s delay1.11.02.11.31.0-1.00.9-1.3-1.4-0.9-0.00.5
Delay disc. indifference point, 4s delay2.62.74.01.32.0-1.82.0-2.0-1.4-1.7-0.11.5
Delay disc. indifference point, 8s delay3.13.25.42.12.0-1.91.9-2.0-2.3-1.60.80.9
Indifference point function ln k3.54.86.8-2.4-2.32.5-2.52.52.62.1-0.0-1.4
Indifference point function log k3.54.86.8-2.4-2.32.5-2.52.52.62.1-0.0-1.4
Patch foraging total patch changes 0 sec0.10.10.60.20.0-0.80.50.1-0.1-0.4-0.20.2
Patch foraging total patch changes 12 sec0.81.12.10.30.7-1.31.2-0.9-0.7-1.3-1.11.4
Patch foraging total patch changes 18 sec1.72.24.50.71.3-1.61.5-1.2-1.1-2.1-1.22.0
Patch foraging total patch changes 24 sec0.91.12.21.11.1-1.01.2-1.0-1.5-1.1-0.30.8
Patch foraging total patch changes 6 sec1.32.03.11.31.2-1.61.7-1.3-1.3-1.8-0.71.4
Patch foraging time to switch 0 sec0.40.62.7-0.70.5-0.40.3-0.20.8-0.5-1.61.1
Patch foraging water rate 0 sec0.20.30.80.1-0.90.5-0.30.6-0.00.40.4-0.7
Patch foraging water rate 12 sec0.50.71.4-0.1-1.00.8-0.51.10.51.00.8-1.2
Patch foraging water rate 18 sec0.20.30.70.3-0.80.6-0.20.60.10.30.5-0.6
Patch foraging water rate 24 sec2.33.25.3-1.6-2.32.2-2.02.31.91.5-0.4-1.1
Patch foraging water rate 6 sec0.91.33.10.3-1.21.1-0.90.90.01.31.8-1.7
Seeking ratio, delayed vs. immediate footshock0.30.31.20.70.6-0.20.3-0.4-0.20.21.1-0.4
Distance traveled before self-admin2.42.54.81.22.2-1.61.9-1.8-1.2-1.7-0.71.6
Distance traveled after self-admin1.41.54.90.10.7-0.80.7-0.8-0.3-1.7-2.21.9
Extensor digitorum longus weight0.41.52.51.61.2-1.61.6-1.1-0.9-0.61.30.0
Bone: elastic displacement0.30.30.7-0.4-0.60.4-0.40.70.60.5-0.9-0.2
Bone: elastic work1.11.44.9-1.6-0.50.2-0.10.71.5-0.4-2.21.2
Bone: endosteal estimation0.71.53.0-1.7-0.81.2-1.31.01.70.0-1.70.8
Bone: endosteal perimeter1.02.04.5-2.1-1.21.6-1.51.12.10.5-1.30.4
Epididymis fat weight2.35.59.2-3.0-2.92.7-2.72.32.42.1-0.3-1.3
Delta time in closed arm before/after self-admin0.30.30.5-0.20.4-0.50.7-0.5-0.5-0.5-0.60.6
Delta time in open arm before/after self-admin0.10.10.30.40.3-0.60.3-0.2-0.1-0.20.20.2
Diff in mean of infusions in LGA sessions0.30.40.90.50.5-0.30.4-0.8-0.9-0.8-0.20.5
Delay discount exponential model param4.24.46.5-2.2-2.52.3-2.32.52.41.8-0.7-1.2
Extinction: sum of active levers before priming1.71.73.51.31.8-1.20.9-1.9-1.4-1.30.51.0
Active lever presses in extinction session 60.20.20.4-0.10.3-0.2-0.2-0.5-0.0-0.5-0.60.5
Bone: final force0.50.82.6-0.80.5-0.40.4-0.40.4-1.2-1.41.6
Bone: final moment0.61.02.8-0.90.4-0.40.5-0.20.5-1.3-1.61.7
Food consumed during 24 hour testing period0.40.41.1-0.9-0.00.2-0.10.00.4-0.8-1.11.1
Glucose0.40.61.9-0.8-0.50.7-0.90.90.7-0.0-1.40.3
Heart weight2.13.05.4-2.0-2.12.1-1.72.31.90.9-1.1-0.6
Delay discount hyperbolic model param4.44.77.1-2.2-2.72.4-2.42.62.32.0-0.6-1.4
Intermittent access intake day 1-15 change0.30.31.01.00.4-0.50.3-0.5-0.9-0.20.7-0.2
Intermittent access intake escalation0.40.41.01.00.5-0.40.2-0.5-0.9-0.30.9-0.2
Intermittent access intake escalation 20.20.20.40.60.2-0.50.3-0.3-0.6-0.20.4-0.1
Intermitt. access day 1 inactive lever presses0.40.51.6-0.40.4-0.20.2-0.20.2-0.9-1.31.2
Intermitt. access day 15 inactive lever presses0.40.41.10.30.5-0.20.2-0.8-0.7-1.0-0.71.0
Intermitt. access escalation Index0.10.10.40.60.5-0.10.1-0.4-0.5-0.30.3-0.1
Intermittent access day 1 total infusions1.01.23.10.01.1-0.80.9-0.9-0.5-1.6-1.11.8
Intermittent access day 15 total infusions1.31.52.70.91.3-1.21.1-1.2-1.2-1.6-0.51.4
Intermittent access terminal intake (last 3 days)0.80.81.30.81.1-1.00.8-1.0-1.0-1.2-0.31.0
Intermittent access total infusions1.92.14.00.61.7-1.31.3-1.5-1.0-2.0-0.92.0
Intermittent access day 1 locomotion0.80.82.2-0.10.7-0.60.6-0.6-0.3-1.4-1.21.5
Intermittent access day 15 total locomotion0.20.20.6-0.20.20.00.0-0.3-0.4-0.8-0.60.6
Intermittent access total locomotion0.60.72.0-0.60.2-0.10.1-0.3-0.2-1.4-1.31.4
Intermittent access standard deviation1.01.03.2-0.20.8-0.80.7-0.7-0.2-1.4-1.21.8
Left kidney weight4.412.327.1-5.2-3.93.8-3.73.44.02.1-3.0-0.4
Right kidney weight5.114.432.3-5.7-4.53.6-3.83.74.11.6-4.00.2
Cocaine induced anxiety1.01.12.1-1.5-0.81.3-1.11.11.40.8-0.8-0.5
Post-drug Anxiety2.32.53.5-1.8-1.71.7-1.71.81.91.3-1.0-0.9
Baseline Anxiety0.20.20.50.5-0.5-0.1-0.20.3-0.40.30.6-0.7
Tail length0.41.12.3-0.7-1.41.2-1.51.50.80.8-0.2-0.8
Length with tail1.86.810.7-2.9-3.32.7-3.13.02.51.8-2.3-1.1
Length without tail2.24.77.8-2.8-2.72.1-2.22.32.11.4-2.4-0.5
Times rat made contact with spout0.20.21.00.60.1-0.30.3-0.4-1.0-0.50.0-0.2
Lifetime Intake2.22.45.50.21.8-1.41.4-1.5-0.9-2.2-1.32.4
Liver weight, left1.22.03.1-1.5-1.71.8-1.21.31.81.6-0.1-1.0
Liver weight, right4.98.212.9-2.8-3.13.6-3.42.82.83.10.4-2.3
Locomotor activity1.21.93.6-1.9-1.91.2-1.21.61.70.7-1.1-0.4
Locomotor testing distance0.10.20.7-0.0-0.70.2-0.20.40.10.40.9-0.8
Locomotor testing rearing0.50.71.9-1.4-1.00.6-0.70.71.10.4-0.8-0.1
Locomotion in novel chamber1.82.28.91.6-0.10.2-0.30.1-0.71.53.0-2.4
Locomotion in novel chamber post-restriction1.11.32.81.31.1-1.10.9-1.4-1.2-0.41.7-0.1
Fecal boli incidents, locomotor time 11.51.63.20.71.2-1.31.3-1.2-1.0-1.8-0.71.7
Change in fecal boli incidents, locomotor task1.21.12.0-0.3-1.31.1-1.10.60.31.31.4-1.4
Time >=10cm from walls, locomotor time 10.40.41.2-0.9-0.40.3-0.30.20.6-0.6-1.11.0
Bouts of movement, locomotor time 10.20.20.5-0.6-0.50.7-0.70.20.20.2-0.1-0.0
Total resting periods, locomotor time 10.10.10.2-0.4-0.10.2-0.2-0.1-0.0-0.3-0.40.4
Rest time, locomotor task time 10.30.31.2-0.50.30.2-0.1-0.2-0.1-0.9-0.71.1
Distance moved, locomotor task time 11.21.32.2-0.9-1.41.1-1.01.21.21.5-0.0-1.3
Vertical activity count, locomotor time 11.11.22.8-0.9-1.71.1-1.11.50.90.9-0.3-0.9
Time >=10cm from walls, locomotor time 20.20.20.5-0.4-0.30.7-0.60.40.5-0.1-0.70.2
Bouts of movement, locomotor time 20.10.10.3-0.00.50.2-0.2-0.3-0.2-0.30.40.2
Total resting periods, locomotor time 20.30.30.90.30.9-0.20.3-0.8-0.6-0.80.30.6
Rest time, locomotor task time 20.50.61.00.71.0-0.50.5-1.0-1.0-1.0-0.20.9
Distance moved, locomotor task time 21.31.52.4-1.2-1.51.3-1.31.41.41.3-0.4-1.0
Vertical activity count, locomotor time 21.31.42.4-1.3-1.61.5-1.51.41.10.7-0.9-0.4
Light reinforcement 10.00.10.2-0.1-0.0-0.20.40.10.2-0.2-0.40.2
Light reinforcement 20.91.21.8-1.1-0.91.3-1.11.11.31.20.6-0.8
Bone: marrow area0.81.63.2-1.8-0.91.2-1.31.01.7-0.0-1.80.8
Bone: maximum diameter1.22.25.7-2.4-1.11.2-1.01.12.0-0.0-2.10.9
Bone: maximum force0.81.44.1-1.10.5-0.40.5-0.40.5-1.5-2.01.9
Bone: maximum moment0.91.65.3-1.20.4-0.40.6-0.20.6-1.5-2.32.0
Mean time between licks in bursts0.60.82.01.11.0-1.31.4-0.9-0.3-0.30.70.1
Mean num. licks in bursts0.50.71.3-1.1-1.00.8-0.90.90.70.5-0.8-0.3
Cd content in liver0.80.92.7-0.2-0.90.6-0.80.60.70.91.7-1.2
Co content in liver0.10.10.40.1-0.0-0.30.3-0.10.2-0.20.6-0.1
Cu content in liver1.92.34.82.21.5-1.71.5-1.5-1.5-0.52.0-0.3
Fe content in liver2.53.05.5-1.9-2.01.9-2.11.92.31.1-1.0-0.5
K content in liver0.70.71.10.61.1-0.91.0-0.9-0.5-0.8-0.51.0
Mg content in liver0.40.40.90.30.9-0.60.6-0.7-0.2-0.8-0.51.0
Mn content in liver0.40.42.60.40.40.00.1-0.6-0.50.31.6-0.5
Na content in liver0.20.20.50.70.4-0.50.4-0.2-0.3-0.10.5-0.2
Rb content in liver0.10.20.40.30.4-0.60.6-0.5-0.4-0.4-0.00.4
Se content in liver1.21.56.20.8-0.60.2-0.30.20.01.42.5-2.0
Sr content in liver2.22.05.12.01.2-1.31.0-1.1-1.7-0.12.2-0.8
Zn content in liver0.40.41.11.10.6-0.80.7-0.7-0.5-0.10.6-0.2
Bone: minimum diameter0.30.51.3-1.1-0.10.3-0.10.10.7-0.6-1.11.1
Time in familiar zone, hab. session 10.40.40.80.60.7-0.60.4-0.9-0.6-0.7-0.10.5
Time in novel zone, hab. session 11.61.52.5-1.4-1.41.2-1.11.51.60.9-1.1-0.5
Total zone transitions, hab. session 12.02.76.72.40.8-1.41.4-1.5-1.80.32.6-1.4
Total locomotion distance, hab. session 10.71.02.61.2-0.3-0.20.1-0.4-0.90.91.6-1.6
Locomotion velocity, hab. session 10.81.12.81.50.2-0.70.4-0.8-1.20.51.7-1.2
Time in familiar zone, hab. session 20.60.62.00.3-0.40.7-0.80.30.01.10.7-1.4
Time in novel zone, hab. session 20.60.61.9-0.30.3-0.60.7-0.4-0.2-1.2-0.71.4
Total zone transitions, hab. session 22.22.84.31.81.7-2.01.9-2.1-1.9-1.60.21.1
Total locomotion distance, hab. session 21.62.13.21.31.4-1.81.8-1.7-1.3-1.6-0.51.4
Locomotion velocity, hab. session 22.02.74.21.61.6-2.02.0-1.9-1.5-1.7-0.31.4
Novel to familiar place preference ratio2.52.64.6-1.5-2.11.6-1.81.81.71.50.3-1.4
Novelty place preference3.53.66.1-1.7-2.52.0-2.22.11.81.90.5-1.8
Time in novel zone, NPP test4.14.27.1-1.8-2.72.2-2.42.22.02.00.6-1.9
Total zone transitions, NPP test2.73.88.12.81.6-2.22.1-2.2-2.5-0.61.7-0.3
Total locomotion distance, NPP test1.21.62.81.71.1-1.71.5-1.6-1.5-0.70.40.4
Locomotion velocity, NPP test1.72.44.02.01.4-1.91.9-1.9-1.8-0.80.60.4
Intraocular pressure0.30.41.1-0.9-0.40.7-0.70.30.50.2-1.00.3
Delta distance traveled before/after self-admin1.61.73.9-1.4-2.01.3-1.71.21.10.5-1.5-0.2
Delta ambulatory time before/after self-admin1.21.33.7-1.2-1.70.7-1.10.81.00.0-1.90.3
Parametrial fat weight0.51.01.7-0.6-1.21.3-1.11.20.40.90.9-1.1
Pavlov. Cond. lever latency0.10.10.3-0.5-0.40.4-0.30.40.40.1-0.50.1
Pavlov. Cond. magazine entry latency1.82.33.61.51.9-1.71.5-1.8-1.4-1.60.01.3
Pavlov. Cond. change in total contacts3.13.44.81.62.2-2.12.1-2.1-1.7-2.00.11.6
Pavlov. Cond. index score0.81.01.30.71.2-1.01.0-1.1-0.9-1.1-0.61.1
Pavlov. Cond. latency score0.40.50.60.50.8-0.80.7-0.7-0.5-0.8-0.60.8
Pavlov. Cond. lever contacts0.50.60.90.71.0-0.90.8-0.8-0.8-0.7-0.20.6
Pavlov. Cond. magazine entry number1.31.62.4-1.3-1.61.3-1.21.61.41.2-0.1-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.40.6-0.1-0.60.5-0.2-0.6-0.30.4-0.1
Pavlov. Cond. lever-magazine prob. diff.0.81.01.50.91.2-1.11.0-1.1-1.0-1.0-0.30.9
Pavlov. Cond. response bias1.41.72.81.11.7-1.41.2-1.6-1.3-1.4-0.01.3
Pavlov. Cond. lever latency0.00.00.1-0.10.00.10.0-0.3-0.20.1-0.2-0.2
Pavlov. Cond. magazine entry latency1.92.13.71.41.6-1.91.8-1.2-1.3-1.70.21.3
Pavlov. Cond. change in total contacts0.81.13.5-0.50.3-0.60.50.10.5-1.3-1.91.9
Pavlov. Cond. index score0.60.71.30.80.9-1.11.1-0.6-0.7-1.00.10.9
Pavlov. Cond. latency score0.81.01.70.91.0-1.31.2-0.7-0.9-1.2-0.01.0
Pavlov. Cond. lever contacts0.00.00.10.0-0.0-0.10.00.40.2-0.00.40.1
Pavlov. Cond. magazine entry number0.40.51.0-0.7-0.81.0-0.90.50.70.8-0.4-0.7
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.50.10.6-0.6-0.5-0.2-0.5-0.80.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.10.70.8-1.01.0-0.5-0.5-0.80.20.7
Pavlov. Cond. response bias0.30.40.80.40.7-0.80.7-0.4-0.2-0.8-0.00.9
Time in closed arm before self-admin1.11.32.51.01.3-1.61.6-0.7-0.5-1.3-0.41.1
Time in closed arm after self-admin0.50.52.4-1.0-0.40.10.20.60.5-0.4-1.50.6
Time in open arm before self-admin0.60.71.3-0.2-0.81.1-0.90.60.21.10.7-1.1
Time in open arm after self-admin0.50.62.20.4-0.30.4-0.40.30.00.91.5-1.1
Bone: periosteal estimation0.61.22.9-1.7-0.50.7-0.60.61.5-0.4-1.71.0
Bone: periosteal perimeter1.42.45.7-2.4-1.21.4-1.21.12.10.2-2.10.8
Bone: post-yield work1.11.53.20.61.2-1.21.0-1.4-0.7-1.8-1.21.5
Progressive ratio test 1 active lever presses1.92.03.90.71.6-1.21.2-1.6-1.2-2.0-0.71.8
Progressive ratio test 1 breakpoint1.21.22.30.61.3-0.91.0-1.3-1.0-1.5-0.51.3
Progressive ratio test 1 inactive lever presses1.92.13.50.71.8-1.51.5-1.4-0.9-1.9-0.61.8
Progressive ratio test 2 active lever presses1.41.53.01.01.5-0.80.8-1.4-1.7-1.60.11.2
Progressive ratio test 2 breakpoint1.41.62.80.81.6-0.91.0-1.4-1.5-1.7-0.41.5
Progressive ratio test 2 inactive lever presses2.73.15.51.72.3-1.51.5-2.0-2.1-2.0-0.11.5
Incentive Sensitization - Responses0.20.20.80.60.30.2-0.2-0.2-0.90.00.7-0.2
Incentive Sensitization - Breakpoint0.20.20.80.50.30.3-0.2-0.2-0.9-0.00.6-0.2
Sum of active levers in priming session hrs 5-60.20.10.30.30.5-0.0-0.3-0.5-0.2-0.4-0.40.4
Progressive ratio0.40.41.30.20.5-0.80.6-0.3-0.1-0.7-1.10.7
Food seeking constrained by brief footshock0.20.20.7-0.20.3-0.40.5-0.3-0.1-0.5-0.80.5
Seeking ratio, punishment vs. effort0.00.00.1-0.10.2-0.00.2-0.3-0.2-0.20.20.2
Retroperitoneal fat weight3.712.020.3-4.5-4.14.0-3.73.83.72.8-1.8-1.5
Reaction time number correct0.81.24.91.00.10.7-0.4-0.1-0.61.12.2-1.5
Reaction time mean minus median0.10.10.4-0.2-0.10.1-0.40.30.30.1-0.60.1
Reaction time mean minus median AUC0.40.51.1-1.0-0.60.8-1.00.80.80.5-0.4-0.2
Reaction time num false alarms0.20.20.6-0.4-0.80.5-0.00.60.50.40.0-0.3
Reaction time num false alarms AUC0.10.10.4-0.1-0.70.30.20.50.30.40.0-0.4
Reaction time trials correct on left0.81.24.91.00.10.7-0.4-0.1-0.61.12.2-1.5
Reaction time trials on left0.81.25.01.10.10.7-0.4-0.2-0.71.02.2-1.5
Reaction time mean0.20.30.9-0.5-0.20.5-0.80.70.60.3-0.90.0
Reaction time mean AUC0.20.20.6-0.3-0.10.4-0.70.50.40.3-0.7-0.0
Median of all reaction times0.10.20.7-0.20.10.2-0.50.40.40.1-0.80.2
Reaction time omissions1.01.43.11.31.8-1.11.0-1.6-1.1-1.00.50.8
Reaction time false alarm rate0.10.20.5-0.6-0.70.10.20.50.60.0-0.50.1
Reaction time premature initiation rate0.60.83.2-0.70.3-0.10.1-0.00.4-1.1-1.81.5
Reaction time premature initiations0.10.20.6-0.30.30.4-0.3-0.00.1-0.5-0.80.7
Std. dev. reaction times0.50.71.5-0.9-0.70.9-1.21.00.90.4-1.0-0.0
Reaction time trials completed0.81.25.01.10.10.7-0.4-0.2-0.71.02.2-1.5
Reaction time trials AUC0.71.03.80.8-0.00.8-0.5-0.0-0.51.01.9-1.4
Run reversals in cocaine runway, females1.01.02.5-0.0-1.00.8-0.91.10.41.40.7-1.6
Run reversals in cocaine runway, males0.20.20.60.1-0.4-0.80.6-0.5-0.50.1-0.2-0.1
Latency to leave start box in cocaine runway0.80.81.9-1.1-0.61.0-0.90.81.41.10.6-0.4
Latency to leave start box in cocaine runway, F0.20.30.90.10.3-0.70.6-0.40.40.31.00.1
Latency to leave start box in cocaine runway, M2.62.55.9-1.8-1.22.4-2.31.51.61.3-0.2-0.6
Std. dev. time between licks in bursts0.40.51.10.60.5-1.01.0-0.6-0.3-0.7-0.40.6
Total sessions with >9 infusions0.80.92.8-0.70.5-0.50.5-0.6-0.1-1.3-1.71.5
Short access day 1 total inactive lever presses2.22.46.80.10.9-1.41.4-1.1-0.4-2.0-2.62.1
Short access day 10 total inactive lever presses0.80.91.9-1.0-1.41.1-1.21.20.70.4-0.9-0.2
Short access day 1 total infusions0.70.72.5-0.30.6-0.60.5-0.5-0.1-1.0-1.61.3
Short access day 10 total infusions1.41.54.8-0.70.9-0.81.0-0.80.0-1.8-1.52.2
Short access total infusions1.82.05.4-0.81.1-0.90.9-0.80.0-1.8-2.32.3
Short access day 1 locomotion1.11.22.50.11.0-1.11.1-0.9-0.3-1.4-1.31.6
Short access day 10 total locomotion0.80.82.60.11.0-0.60.7-0.5-0.5-1.6-0.21.6
Short access total locomotion1.51.64.3-0.80.5-1.01.0-0.50.1-1.7-2.02.1
One hour access (0.3 mA shock)3.94.57.62.12.8-2.02.2-2.4-2.4-2.11.21.5
Compulsive drug intake1.31.34.01.70.7-0.40.5-0.7-1.8-0.12.0-0.7
One hour access (shock baseline)0.60.71.40.31.2-0.80.9-0.9-0.4-1.0-0.01.0
Social response proportion0.40.51.2-0.40.4-0.70.7-0.01.1-0.5-0.60.9
Social responses0.91.22.90.81.1-1.41.7-1.0-0.7-1.1-0.31.0
Social time3.24.27.61.82.2-2.82.6-2.2-1.7-2.1-0.41.8
Soleus weight0.61.94.41.31.0-1.31.5-1.3-2.1-1.5-0.51.2
Bone: stiffness0.71.13.9-1.30.10.1-0.00.20.9-1.1-2.01.5
Tibialis anterior weight2.06.710.62.92.8-3.23.3-2.7-2.8-2.31.31.3
Time to tail flick, vehicle, before self-admin0.10.10.50.0-0.40.6-0.70.1-0.2-0.1-0.3-0.1
Time to tail flick, vehicle, after self-admin0.40.41.0-0.0-1.00.6-0.70.80.30.80.2-0.9
Time to tail flick, test, before self-admin0.80.82.10.70.6-1.41.3-0.9-1.0-0.50.50.2
Time to tail flick, test, after self-admin0.30.31.01.00.4-0.60.3-0.3-0.60.20.7-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.60.10.3-0.80.7-0.00.1-0.2-0.30.3
Delta time to tail flick, test, before/after SA0.60.51.90.9-0.20.4-0.70.4-0.10.80.8-1.4
Tibia length0.10.30.8-0.9-0.20.4-0.50.10.5-0.4-0.70.7
Ambulatory time before self-admin1.81.93.51.41.9-1.31.7-1.5-1.4-1.20.30.9
Ambulatory time after self-admin1.01.02.30.70.5-1.10.9-0.9-0.6-1.3-1.51.2
Bone: tissue strength0.20.20.3-0.6-0.50.4-0.40.50.50.3-0.5-0.1
Total heroin consumption0.60.71.50.60.8-0.91.1-1.2-0.8-0.90.70.6
Bone: trabecular number0.40.61.2-0.4-0.71.0-1.10.60.61.10.4-1.1
Bone: trabecular spacing0.81.03.0-0.30.5-0.60.7-0.9-0.4-1.5-1.21.7
Bone: trabecular thickness0.60.71.2-0.3-0.20.9-1.00.70.51.11.1-1.1
Bone: trabecular tissue density0.10.20.40.3-0.3-0.30.40.60.30.30.5-0.7
Water consumed over 24 hours0.10.10.30.3-0.1-0.40.3-0.2-0.5-0.4-0.30.0
Number of responses in last shaping day5.15.38.41.32.9-2.72.7-2.5-1.5-2.7-0.82.7