Hub : Genes

Nploc4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Nploc4 0.8 0 0.0e+00 0.59 0.62 0.63 0.62 1.6e-67 3.3e-74 9.2e-75 7.4e-74
2 NAcc isoform ratio NM_080577.2 0.03 0.02 1.1e-04 0.04 0.03 0.03 0.03 4.5e-05 4.6e-04 5.6e-04 4.2e-04
3 NAcc isoform ratio XM_039085086.1 0.03 0.02 1.9e-04 0.03 0.02 0.02 0.02 1.6e-04 1.7e-03 2.9e-03 3.0e-03
4 Liver gene expression Nploc4 0.02 0.02 3.9e-03 0.02 0.01 0 0.01 6.6e-03 3.0e-02 9.1e-02 3.1e-02
5 PL isoform ratio NM_080577.2 0.04 0.03 7.8e-05 0.06 0.04 0.05 0.06 8.9e-07 2.2e-05 4.0e-06 1.1e-06
6 PL isoform ratio XM_039085086.1 0.04 0.03 4.7e-05 0.06 0.04 0.04 0.06 4.7e-07 1.2e-05 1.3e-05 5.5e-07
7 Brain alternative polyA XM_039085086.1 0.05 0.03 3.5e-05 0.02 0.04 0.03 0.03 2.6e-03 2.9e-04 1.9e-03 7.8e-04
8 Brain alternative polyA NM_080577.2 0.05 0.03 2.9e-05 0.03 0.04 0.03 0.03 2.2e-03 2.4e-04 1.4e-03 7.1e-04
9 NAcc alternative polyA NM_080577.2 0.02 0.02 6.0e-03 0.01 0.01 0.01 0.01 2.5e-02 1.4e-02 2.1e-02 3.7e-02
10 pVTA gene expression Nploc4 0.79 0.08 0.0e+00 0.41 0.43 0.43 0.42 5.2e-19 3.3e-20 4.6e-20 1.9e-19
11 Brain mRNA stability Nploc4 0.51 0.33 0.0e+00 0.21 0.28 0.28 0.29 4.4e-19 1.1e-26 1.3e-26 5.4e-27
12 OFC gene expression Nploc4 0.48 0.16 1.5e-08 0.26 0.14 0.29 0.27 6.0e-07 3.4e-04 1.3e-07 4.2e-07
13 Brain isoform ratio NM_080577.2 0.06 0.04 6.4e-07 0.07 0.06 0.06 0.07 5.5e-07 6.8e-06 6.0e-06 7.7e-07
14 Brain isoform ratio XM_039085086.1 0.06 0.04 1.2e-06 0.07 0.05 0.05 0.06 6.7e-07 1.1e-05 1.1e-05 1.9e-06
15 LHb gene expression Nploc4 0.52 0.18 2.2e-08 0.14 0.06 0.2 0.1 3.0e-04 1.9e-02 1.4e-05 2.8e-03
16 BLA gene expression Nploc4 0.53 0.15 0.0e+00 0.41 0.46 0.45 0.46 2.5e-23 2.6e-27 1.4e-26 5.1e-27
17 IL gene expression Nploc4 0.29 0.16 1.0e-04 0.05 0.09 0.1 0.09 2.0e-02 4.3e-03 2.5e-03 4.0e-03
18 OFC mRNA stability Nploc4 0.21 0.12 1.4e-03 0.11 0.06 0.08 0.13 1.5e-03 1.9e-02 6.7e-03 5.2e-04
19 NAcc gene expression Nploc4 0.16 0.07 0.0e+00 0.18 0.18 0.17 0.18 3.5e-20 1.9e-20 8.2e-20 7.4e-21
20 NAcc mRNA stability Nploc4 0.05 0.03 8.8e-06 0.04 0.04 0.03 0.03 3.4e-05 2.0e-05 2.0e-04 1.5e-04
21 Adipose mRNA stability Nploc4 0.05 0.04 2.5e-05 0.04 0.04 0.04 0.04 1.0e-05 7.8e-05 1.8e-05 4.6e-05
22 PL mRNA stability Nploc4 0.08 0.05 1.4e-09 0.09 0.09 0.09 0.09 5.1e-10 5.6e-10 3.6e-10 2.8e-10
23 PL alternative polyA XM_039085086.1 0.05 0.04 2.3e-05 0.03 0.04 0.05 0.04 4.2e-04 3.8e-05 3.4e-06 4.0e-05
24 PL alternative polyA NM_080577.2 0.05 0.04 1.9e-05 0.03 0.04 0.05 0.04 3.1e-04 2.8e-05 1.3e-06 2.9e-05
25 BLA mRNA stability Nploc4 0.09 0.06 9.6e-05 0.06 0.06 0.06 0.06 3.7e-04 4.3e-04 4.2e-04 4.8e-04
26 RMTg gene expression Nploc4 0.16 0.1 5.8e-03 0.1 0.07 0.07 0.07 1.2e-03 6.3e-03 5.7e-03 4.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.30.60.9-0.7-0.70.70.7-0.60.6-0.80.80.80.90.8-0.9-0.50.5-0.90.8-0.70.70.80.8-0.10.80.9-0.9-0.80.9
Area under the delay curve1.51.63.01.71.7-1.7-1.51.2-1.21.3-1.3-1.4-1.6-1.31.31.3-1.31.3-1.11.3-1.1-1.1-0.9-1.4-1.00.2-0.30.8-0.6
BMI with tail1.13.46.1-1.8-1.81.81.7-1.81.8-2.02.01.82.01.8-2.1-1.51.5-1.91.9-1.52.21.92.0-0.91.62.4-2.5-1.71.3
BMI without tail8.718.024.2-4.1-4.14.14.1-3.93.9-4.74.74.54.34.4-4.6-4.34.3-4.74.7-4.74.64.44.9-1.44.63.2-3.2-4.24.4
Body weight3.916.223.8-4.8-4.74.74.6-4.94.9-4.44.44.44.54.3-3.9-4.24.2-3.93.9-4.03.23.73.42.43.53.5-3.5-2.92.5
Weight adjusted by age2.02.24.2-1.6-1.81.82.0-2.12.1-1.91.91.71.21.7-1.9-1.51.5-1.41.4-1.31.31.31.21.10.90.6-0.6-0.80.4
Bone surface0.20.41.1-0.8-0.80.80.8-0.70.7-0.50.50.61.00.6-0.4-0.60.6-0.50.4-0.5-0.10.50.31.10.40.3-0.3-0.40.4
Bone volume0.30.50.9-0.8-0.80.80.8-0.80.8-0.70.70.81.00.8-0.8-0.60.6-0.80.7-0.70.40.70.60.50.70.4-0.5-0.60.6
Breakpoint value in progressive ratio session0.20.21.1-0.3-0.50.50.4-0.60.6-0.30.3-0.0-0.1-0.0-0.1-0.10.10.1-0.10.11.0-0.3-0.1-0.3-0.2-0.50.50.5-0.7
Number of licking bursts0.40.51.3-0.8-0.60.60.6-0.50.5-0.60.60.81.10.8-0.5-0.40.4-0.80.8-0.60.50.90.70.40.80.8-0.8-1.00.8
Context. condit. distance diff. score2.32.85.2-1.3-1.01.01.0-1.01.0-1.71.71.71.61.9-1.8-1.01.0-1.92.0-1.72.12.12.2-1.21.92.0-2.0-2.32.0
Locomotion velocity, session 14.44.86.92.42.0-2.0-2.02.0-2.02.3-2.3-2.3-2.3-2.42.31.8-1.82.4-2.42.2-2.6-2.4-2.30.0-2.4-2.22.22.3-2.2
Locomotion distance, session 11.21.63.61.71.8-1.8-1.81.8-1.81.3-1.3-1.2-1.3-1.00.91.7-1.70.9-0.71.1-0.5-0.6-0.4-1.9-0.5-0.10.10.00.2
Locomotion velocity, session 24.85.67.42.52.7-2.7-2.72.7-2.72.7-2.7-2.6-2.4-2.52.62.5-2.52.4-2.42.4-2.4-2.2-2.2-0.6-2.2-2.01.91.7-1.5
Locomotion distance, session 20.20.21.30.40.7-0.7-0.60.6-0.60.2-0.2-0.1-0.30.0-0.00.4-0.4-0.10.2-0.10.30.30.4-1.10.40.5-0.6-0.60.9
Locomotion velocity, session 32.52.93.91.71.7-1.7-1.71.7-1.71.8-1.8-1.9-1.7-1.81.91.9-1.92.0-1.81.8-1.7-1.8-1.7-0.4-1.8-1.31.31.6-1.8
Locomotion distance, session 32.93.14.62.12.0-2.0-2.12.1-2.11.9-1.9-1.9-1.8-1.81.82.1-2.11.9-1.71.9-1.3-1.6-1.4-1.3-1.6-1.21.21.2-1.2
Stereotopy head waving bouts, day 31.01.22.30.91.0-1.0-1.01.0-1.01.2-1.2-1.2-1.0-1.21.51.0-1.01.3-1.21.1-1.1-1.2-1.20.2-1.2-1.01.01.1-1.1
Stereotopy head waving duration, day 30.40.51.20.50.8-0.8-0.70.7-0.70.8-0.8-0.7-0.7-0.71.10.7-0.70.9-0.70.7-0.6-0.7-0.80.1-0.7-0.50.50.6-0.6
Locomotion velocity, session 70.40.51.10.80.8-0.8-0.90.9-0.90.7-0.7-0.7-0.6-0.60.41.1-1.10.6-0.50.9-0.2-0.4-0.4-0.9-0.60.0-0.10.2-0.4
Locomotion distance, session 71.11.56.61.51.8-1.8-1.71.7-1.71.0-1.0-1.0-1.2-0.70.31.7-1.70.5-0.31.00.4-0.20.0-2.6-0.30.7-0.7-0.50.4
Stereotopy head waving bouts, day 70.20.20.4-0.5-0.60.60.5-0.50.5-0.50.50.50.50.5-0.3-0.40.4-0.40.5-0.40.60.50.5-0.10.4-0.10.1-0.30.3
Stereotopy head waving duration, day 70.30.30.8-0.9-0.80.80.7-0.70.7-0.50.50.60.90.6-0.1-0.50.5-0.40.4-0.50.20.50.30.90.4-0.20.2-0.30.2
Locomotion velocity, session 80.30.32.10.30.6-0.6-0.60.6-0.6-0.00.00.1-0.10.2-0.40.3-0.3-0.40.5-0.20.70.50.7-1.40.70.5-0.5-0.91.1
Locomotion distance, session 82.53.78.3-1.1-0.60.60.6-0.60.6-1.71.71.71.52.0-2.0-0.70.7-2.12.3-1.82.52.52.6-2.22.42.6-2.6-2.92.8
Degree of sensitization distance1.61.62.8-1.2-0.80.80.9-0.90.9-1.31.31.31.01.3-1.7-1.11.1-1.51.4-1.21.71.41.4-0.41.41.7-1.7-1.51.4
Degree of sensitization stereotypy0.60.61.1-0.9-0.90.90.8-0.80.8-0.90.90.90.90.9-0.8-0.70.7-0.80.9-0.81.00.90.9-0.20.80.1-0.1-0.70.6
Conditioned locomotion5.76.78.0-2.8-2.62.62.6-2.62.6-2.82.82.82.72.8-2.8-2.72.7-2.82.7-2.72.52.62.60.52.62.3-2.2-2.42.3
Cocaine response after cond. corrected0.30.30.90.70.4-0.4-0.40.3-0.30.4-0.4-0.6-1.0-0.70.30.2-0.20.6-0.60.5-0.2-0.8-0.5-0.6-0.6-0.80.70.9-0.7
Cocaine response after cond. not corrected0.90.91.81.10.9-0.9-0.90.9-0.90.9-0.9-1.1-1.3-1.10.80.7-0.71.0-1.00.8-0.8-1.1-0.8-0.7-0.9-1.31.31.1-0.8
Cocaine response before conditioning0.40.51.00.70.9-0.9-0.91.0-1.00.8-0.8-0.6-0.3-0.50.81.0-1.00.5-0.50.6-0.8-0.2-0.4-0.2-0.3-0.50.6-0.10.1
Saline control response2.83.75.1-2.2-2.32.32.3-2.32.3-2.12.12.12.11.9-1.6-2.32.3-1.91.8-2.11.21.71.61.21.81.5-1.5-1.31.3
Bone: connectivity density0.20.31.1-0.5-0.20.20.1-0.10.1-0.30.30.50.80.7-0.5-0.10.1-0.60.7-0.50.40.80.6-0.10.70.9-0.9-1.01.1
Bone: cortical apparent density2.63.44.72.22.1-2.1-2.12.1-2.12.0-2.0-2.1-2.1-2.01.82.1-2.12.0-1.82.0-1.3-1.8-1.6-1.3-1.8-0.80.81.4-1.5
Bone: cortical area4.36.611.8-3.2-3.43.43.4-3.43.4-2.82.82.73.02.5-2.4-3.03.0-2.42.1-2.41.42.01.72.42.01.1-1.2-1.21.2
Bone: cortical porosity0.91.03.8-0.1-0.50.50.5-0.60.60.3-0.3-0.5-0.5-0.80.7-0.40.40.9-1.00.6-1.1-1.3-1.31.7-1.3-1.01.02.0-2.0
Bone: cortical porosity0.50.62.3-0.4-0.80.80.8-0.90.9-0.10.1-0.1-0.2-0.40.2-0.70.70.4-0.60.2-0.6-0.9-0.81.5-0.8-0.70.71.5-1.5
Bone: cortical thickness2.74.49.3-2.7-3.13.13.1-3.03.0-2.22.22.12.31.8-1.8-2.72.7-1.71.4-1.81.01.21.02.71.20.7-0.8-0.30.3
Bone: cortical thickness0.91.12.3-1.3-1.51.51.5-1.51.5-1.21.21.11.10.9-1.1-1.31.3-0.90.8-0.80.70.60.70.90.70.3-0.3-0.20.2
Bone: cortical tissue density3.03.95.42.32.3-2.3-2.22.2-2.22.1-2.1-2.2-2.3-2.11.92.3-2.32.1-2.02.2-1.4-1.9-1.7-1.4-1.9-0.80.91.5-1.6
Condit. Reinf. active minus inactive responses2.32.63.8-1.7-1.91.91.8-1.81.8-1.81.81.81.71.7-1.9-1.91.9-1.81.6-1.71.41.51.50.41.60.9-0.9-1.21.2
Condit. Reinf. active-inactive response ratio1.11.12.0-1.1-1.31.31.2-1.21.2-1.21.21.11.01.1-1.4-1.11.1-1.11.1-1.01.31.01.0-0.01.00.8-0.8-0.70.6
Condit. Reinf. active responses4.35.37.3-2.4-2.62.62.5-2.52.5-2.52.52.52.42.4-2.5-2.72.7-2.52.3-2.51.82.22.20.92.31.3-1.3-1.71.9
Condit. Reinf. inactive responses1.11.32.1-1.3-1.21.21.2-1.21.2-1.31.31.31.21.2-1.2-1.51.5-1.31.2-1.40.81.11.10.41.20.4-0.4-0.91.1
Incentive salience index mean2.02.53.2-1.6-1.81.81.7-1.71.7-1.71.71.71.81.7-1.8-1.71.7-1.81.6-1.61.31.61.50.61.61.0-1.0-1.31.2
Condit. Reinf. lever presses0.20.30.7-0.4-0.30.30.2-0.20.2-0.40.40.50.70.6-0.6-0.10.1-0.60.6-0.40.50.80.6-0.10.70.6-0.6-0.90.7
Condit. Reinf. active minus inactive responses0.91.12.2-1.3-1.01.01.0-1.11.1-1.11.11.20.91.1-0.9-1.51.5-1.11.1-1.30.91.00.90.81.10.8-0.8-0.91.0
Condit. Reinf. active-inactive response ratio1.41.43.4-1.7-1.51.51.5-1.51.5-1.21.21.21.01.1-0.8-1.81.8-1.00.9-1.40.50.70.61.60.80.3-0.3-0.40.5
Condit. Reinf. active responses0.40.61.3-0.7-0.50.50.5-0.60.6-0.80.80.80.30.7-0.9-1.01.0-0.90.9-0.91.20.70.9-0.31.00.9-0.9-0.80.9
Condit. Reinf. inactive responses0.20.32.30.80.7-0.7-0.70.7-0.70.3-0.3-0.4-0.7-0.3-0.00.6-0.60.1-0.10.40.5-0.10.2-1.5-0.00.4-0.4-0.10.2
Condit. Reinf. lever presses0.81.03.3-0.6-0.50.50.5-0.60.6-1.01.00.90.20.9-1.3-0.80.8-1.11.1-0.91.80.91.3-1.21.11.5-1.5-1.01.0
Condit. Reinf. lever reinforcers received0.71.02.9-0.7-0.50.50.5-0.60.6-1.01.00.90.20.9-1.2-1.01.0-1.11.1-1.01.70.91.2-1.01.11.3-1.4-1.01.1
Conditioned reinforcement - actives0.60.63.6-0.9-0.40.40.2-0.30.3-0.50.50.70.60.8-0.5-0.10.1-0.60.8-0.40.80.80.60.40.91.9-1.9-0.70.7
Conditioned reinforcement - inactives0.91.01.7-1.3-1.11.11.1-1.11.1-1.21.21.10.31.2-1.2-1.31.3-1.00.9-1.10.80.70.71.10.90.7-0.7-0.40.7
Conditioned locomotion0.40.52.5-0.9-0.30.30.2-0.60.6-0.50.50.60.40.7-0.4-0.10.1-0.40.6-0.30.60.60.31.20.71.6-1.6-0.50.3
Patch foraging indifference point 0 sec0.10.10.6-0.3-0.40.40.4-0.30.3-0.40.40.30.20.3-0.4-0.20.2-0.20.3-0.20.70.20.3-0.20.20.7-0.6-0.2-0.0
Patch foraging indifference point AUC0.00.00.30.1-0.00.0-0.10.2-0.2-0.10.10.0-0.3-0.0-0.1-0.20.2-0.20.1-0.30.1-0.00.2-0.30.40.0-0.0-0.00.6
Delay disc. indifference point, 0s delay0.10.21.50.50.3-0.3-0.2-0.10.10.1-0.1-0.1-0.2-0.00.10.4-0.40.2-0.00.3-0.10.0-0.10.0-0.01.2-1.2-0.2-0.2
Delay disc. indifference point, 16s delay0.90.94.81.21.4-1.4-1.21.1-1.10.6-0.6-0.7-1.2-0.30.21.2-1.20.5-0.10.50.1-0.20.1-2.2-0.11.3-1.3-0.20.4
Delay disc. indifference point, 2s delay0.50.51.21.10.9-0.9-0.90.4-0.40.7-0.7-0.8-1.0-0.80.90.7-0.70.9-0.70.9-0.8-0.7-0.7-0.2-0.6-0.0-0.00.6-0.6
Delay disc. indifference point, 24s delay5.75.57.32.62.7-2.7-2.62.4-2.42.6-2.6-2.6-2.6-2.52.32.6-2.62.5-2.42.7-2.0-2.3-2.2-1.4-2.3-1.21.22.1-1.9
Delay disc. indifference point, 4s delay0.60.61.50.91.0-1.0-0.80.6-0.60.9-0.9-0.9-0.7-1.11.20.5-0.50.9-0.80.8-0.7-0.8-0.8-0.4-0.60.8-0.90.5-0.4
Delay disc. indifference point, 8s delay1.41.42.01.41.3-1.3-1.21.1-1.11.3-1.3-1.4-1.3-1.41.31.0-1.01.3-1.31.3-1.4-1.3-1.2-0.5-1.2-0.60.51.2-1.0
Indifference point function ln k0.50.61.31.01.1-1.1-1.01.0-1.00.8-0.8-0.9-0.8-0.80.51.1-1.10.7-0.61.0-0.2-0.5-0.5-1.1-0.8-0.10.00.3-0.5
Indifference point function log k0.50.61.31.01.1-1.1-1.01.0-1.00.8-0.8-0.9-0.8-0.80.51.1-1.10.7-0.61.0-0.2-0.5-0.5-1.1-0.8-0.10.00.3-0.5
Patch foraging total patch changes 0 sec0.10.21.2-0.3-0.40.40.4-0.20.2-0.60.60.40.10.4-0.6-0.30.3-0.30.4-0.31.10.30.5-0.70.40.7-0.7-0.30.2
Patch foraging total patch changes 12 sec0.00.00.20.1-0.10.1-0.00.1-0.10.0-0.0-0.2-0.4-0.30.1-0.10.10.2-0.20.0-0.0-0.4-0.2-0.0-0.1-0.20.20.4-0.2
Patch foraging total patch changes 18 sec0.30.32.60.30.1-0.1-0.20.3-0.3-0.30.40.2-0.30.3-0.50.1-0.1-0.30.5-0.51.10.40.8-1.60.50.9-0.9-0.60.6
Patch foraging total patch changes 24 sec0.60.81.9-0.9-0.80.80.9-0.90.9-1.11.11.00.60.9-1.3-0.80.8-0.91.0-0.81.40.80.9-0.00.80.6-0.6-0.70.4
Patch foraging total patch changes 6 sec0.10.20.8-0.6-0.70.70.6-0.60.6-0.50.50.40.20.3-0.0-0.70.7-0.20.2-0.50.20.10.10.90.30.00.00.10.0
Patch foraging time to switch 0 sec0.50.81.40.90.8-0.8-0.90.8-0.81.0-1.0-0.9-0.7-0.80.90.9-0.90.9-0.90.9-1.2-0.8-0.8-0.2-1.0-1.21.20.7-0.8
Patch foraging water rate 0 sec2.84.58.3-2.3-2.12.12.1-2.12.1-2.52.52.31.62.2-2.4-2.12.1-2.32.3-2.32.92.02.20.02.31.8-1.8-1.91.8
Patch foraging water rate 12 sec0.91.44.2-0.9-0.60.60.6-0.50.5-1.21.21.10.61.1-1.3-0.90.9-1.31.4-1.22.11.21.5-1.31.41.5-1.5-1.41.4
Patch foraging water rate 18 sec1.82.45.2-1.5-1.21.21.2-1.21.2-1.61.61.61.31.7-1.8-1.11.1-1.71.8-1.62.31.71.8-0.41.81.8-1.8-1.81.7
Patch foraging water rate 24 sec4.56.315.2-2.2-1.91.91.9-2.02.0-2.72.72.51.72.6-2.9-2.12.1-2.72.8-2.53.92.63.0-1.52.73.0-3.1-2.62.5
Patch foraging water rate 6 sec0.50.72.2-0.8-0.40.40.4-0.60.6-0.80.80.80.50.9-0.9-0.50.5-0.91.0-0.91.50.90.9-0.30.91.5-1.5-1.00.9
Seeking ratio, delayed vs. immediate footshock1.51.73.4-1.3-1.61.61.5-1.61.6-1.41.41.41.81.4-1.2-1.41.4-1.31.2-1.40.41.31.10.71.30.6-0.5-1.11.0
Distance traveled before self-admin0.50.51.3-0.8-1.11.11.1-1.01.0-0.80.80.50.80.4-1.0-0.60.6-0.50.3-0.20.50.20.20.4-0.0-0.90.9-0.0-0.7
Distance traveled after self-admin0.91.02.5-0.9-0.90.91.0-0.80.8-1.21.21.00.91.0-1.2-0.90.9-1.11.1-1.11.61.01.3-0.91.00.8-0.8-1.20.8
Extensor digitorum longus weight0.62.35.1-1.0-0.70.70.7-0.60.6-1.41.41.41.21.5-1.9-0.60.6-1.71.8-1.32.31.82.0-1.91.81.9-1.9-2.12.0
Bone: elastic displacement0.70.81.9-1.2-1.41.41.3-1.21.2-0.90.90.80.90.7-0.9-1.11.1-0.70.5-0.70.80.40.41.00.50.2-0.20.0-0.0
Bone: elastic work3.03.99.6-2.4-3.13.13.1-2.92.9-2.12.01.81.91.4-1.6-2.72.7-1.41.0-1.60.80.60.62.60.8-0.00.00.4-0.4
Bone: endosteal estimation0.30.61.5-0.4-0.30.30.3-0.20.2-0.70.70.70.60.8-0.8-0.30.3-0.91.0-0.70.91.01.1-1.01.10.6-0.6-1.21.2
Bone: endosteal perimeter0.51.12.2-1.2-1.41.41.4-1.41.4-1.11.11.21.51.1-1.0-1.11.1-1.00.9-0.90.10.90.81.00.90.3-0.3-0.60.6
Epididymis fat weight1.74.06.8-2.1-2.12.11.9-2.02.0-2.12.12.12.32.1-2.2-1.51.5-2.02.1-1.72.12.12.00.21.92.6-2.6-1.91.5
Delta time in closed arm before/after self-admin0.20.23.2-0.60.2-0.2-0.2-0.10.10.1-0.10.3-0.10.40.20.0-0.0-0.10.2-0.1-0.30.2-0.21.80.20.2-0.2-0.10.5
Delta time in open arm before/after self-admin0.40.32.50.0-0.30.30.3-0.10.1-0.50.50.30.40.5-0.70.2-0.2-0.40.5-0.21.10.50.7-1.60.31.0-0.9-0.6-0.0
Diff in mean of infusions in LGA sessions0.30.30.90.50.4-0.4-0.50.5-0.50.5-0.5-0.6-0.4-0.40.61.0-1.00.7-0.50.7-0.1-0.5-0.6-0.2-0.6-0.50.50.5-0.8
Delay discount exponential model param2.42.54.3-2.1-2.02.01.9-1.61.6-1.71.71.81.91.8-1.7-1.61.6-1.71.6-1.61.41.51.31.41.40.2-0.1-1.20.9
Extinction: sum of active levers before priming1.61.63.41.21.1-1.1-1.21.4-1.41.3-1.3-1.4-1.2-1.31.01.8-1.81.4-1.31.7-0.4-1.3-1.3-0.8-1.4-0.60.61.1-1.6
Active lever presses in extinction session 60.90.92.80.60.7-0.7-0.70.4-0.40.6-0.6-1.0-1.5-0.80.51.1-1.11.1-0.91.20.5-1.2-1.0-0.4-1.2-0.90.81.2-1.7
Bone: final force4.36.911.5-3.1-3.33.33.4-3.43.4-3.03.02.92.82.6-2.4-3.13.1-2.52.4-2.71.82.12.11.82.21.5-1.5-1.41.4
Bone: final moment4.67.513.0-3.2-3.63.63.6-3.63.6-3.13.12.92.92.7-2.6-3.33.3-2.62.4-2.71.92.12.11.92.21.5-1.5-1.31.3
Food consumed during 24 hour testing period0.50.61.7-0.9-0.80.80.8-0.90.9-0.90.90.80.60.7-1.1-0.80.8-0.90.8-0.51.30.70.70.10.70.6-0.6-0.50.4
Glucose6.910.315.83.12.6-2.6-2.62.6-2.63.1-3.2-3.5-3.7-3.73.02.4-2.43.5-3.73.4-2.9-3.9-3.5-0.4-3.8-3.53.54.0-3.9
Heart weight0.30.40.8-0.5-0.70.70.9-0.80.8-0.80.80.70.70.6-0.7-0.80.8-0.70.6-0.80.50.60.7-0.10.50.4-0.4-0.40.1
Delay discount hyperbolic model param2.22.44.2-2.0-2.02.01.8-1.51.5-1.71.71.81.91.8-1.7-1.51.5-1.71.5-1.61.41.51.31.31.30.1-0.0-1.10.9
Intermittent access intake day 1-15 change0.40.40.9-0.6-1.01.00.8-0.80.8-0.70.70.60.40.6-0.8-0.90.9-0.80.4-0.70.20.20.40.50.5-0.60.6-0.20.4
Intermittent access intake escalation0.50.50.9-0.7-0.90.90.8-0.90.9-0.80.80.70.50.7-0.8-0.90.9-0.80.6-0.80.40.40.60.30.6-0.0-0.0-0.40.5
Intermittent access intake escalation 20.80.82.5-1.2-1.31.31.2-1.61.6-0.90.90.80.80.8-0.7-1.01.0-0.60.4-0.60.30.20.21.30.3-0.60.60.1-0.2
Intermitt. access day 1 inactive lever presses0.50.61.2-1.0-1.11.11.0-0.80.8-1.01.00.80.20.7-1.0-1.01.0-0.60.6-0.80.90.40.50.40.40.00.0-0.10.1
Intermitt. access day 15 inactive lever presses1.82.04.0-1.6-1.21.21.3-1.21.2-1.51.51.50.81.7-2.0-1.21.2-1.61.6-1.41.81.31.40.41.31.7-1.6-1.31.1
Intermitt. access escalation Index1.91.72.6-1.3-1.01.01.1-1.11.1-1.41.41.51.21.6-1.5-1.11.1-1.51.6-1.41.11.51.50.31.61.1-1.1-1.51.5
Intermittent access day 1 total infusions0.40.40.9-0.7-0.80.80.7-0.40.4-0.70.70.71.00.6-0.4-0.90.9-0.60.6-0.80.40.80.60.20.60.6-0.6-0.50.7
Intermittent access day 15 total infusions0.80.91.3-1.0-1.11.11.0-0.90.9-1.11.11.10.91.1-0.9-1.21.2-1.11.0-1.10.61.01.00.31.00.7-0.6-0.70.9
Intermittent access terminal intake (last 3 days)1.11.22.0-1.4-1.31.31.2-1.21.2-1.21.21.21.21.2-1.0-1.31.3-1.11.0-1.20.81.10.91.01.10.7-0.7-0.60.8
Intermittent access total infusions0.70.81.2-1.0-1.01.00.9-0.80.8-0.90.91.01.01.0-0.8-1.11.1-0.90.9-1.10.70.90.80.40.90.8-0.7-0.70.9
Intermittent access day 1 locomotion0.80.82.2-0.9-0.70.70.6-0.90.9-0.90.90.90.61.0-0.7-0.80.8-0.81.0-0.90.71.00.80.41.01.5-1.5-0.70.9
Intermittent access day 15 total locomotion0.30.31.5-0.9-0.70.70.5-0.70.7-0.50.50.60.50.5-0.0-0.80.8-0.40.4-0.60.20.40.21.20.60.1-0.2-0.10.3
Intermittent access total locomotion0.50.61.2-1.1-0.70.70.6-0.80.8-0.80.80.80.50.8-0.6-0.80.8-0.70.7-0.80.60.70.50.90.90.7-0.7-0.40.5
Intermittent access standard deviation1.11.23.00.90.7-0.7-0.60.4-0.41.0-1.0-1.2-1.0-1.20.80.9-0.91.2-1.31.5-0.7-1.3-1.40.2-1.4-1.51.51.4-1.7
Left kidney weight0.10.33.3-0.3-0.30.30.2-0.50.50.3-0.3-0.10.3-0.11.00.0-0.00.6-0.40.2-1.1-0.3-0.71.8-0.30.0-0.00.5-0.5
Right kidney weight0.10.22.3-0.3-0.00.0-0.0-0.10.10.3-0.3-0.00.4-0.10.90.2-0.20.4-0.30.2-0.8-0.1-0.51.5-0.10.5-0.40.0-0.2
Cocaine induced anxiety1.31.53.8-1.5-1.51.51.9-1.91.9-1.61.51.10.80.9-1.7-1.51.5-1.00.6-0.91.10.50.31.40.3-0.70.80.2-0.7
Post-drug Anxiety0.20.20.8-0.2-0.00.00.4-0.30.3-0.30.3-0.1-0.5-0.1-0.7-0.40.4-0.0-0.20.10.6-0.4-0.30.0-0.5-0.90.90.6-0.8
Baseline Anxiety4.34.68.62.52.7-2.7-2.92.8-2.82.5-2.5-2.3-2.3-2.12.12.5-2.52.1-1.82.1-1.7-1.8-1.5-1.7-1.7-0.80.71.0-0.7
Tail length6.218.925.7-4.9-4.74.74.7-4.64.6-4.84.84.94.54.7-4.1-4.94.9-4.64.5-5.13.44.44.21.94.62.4-2.3-3.74.1
Length with tail1.96.814.0-3.4-3.23.23.3-3.43.4-2.72.62.92.92.7-2.0-2.92.9-2.22.1-2.71.12.11.53.72.11.4-1.4-1.31.2
Length without tail1.43.09.60.70.9-0.9-0.80.4-0.41.7-1.7-1.5-1.1-1.52.01.4-1.42.1-2.11.9-2.2-1.9-2.63.1-2.2-0.50.52.3-2.8
Times rat made contact with spout0.40.42.3-0.8-0.90.90.9-0.90.9-0.40.40.30.1-0.0-0.1-0.90.9-0.0-0.2-0.20.3-0.3-0.41.5-0.2-0.70.60.9-0.8
Lifetime Intake0.20.20.4-0.7-0.50.50.4-0.40.4-0.50.50.50.60.6-0.4-0.60.6-0.50.5-0.60.30.50.40.40.50.4-0.4-0.40.5
Liver weight, left0.60.92.20.60.4-0.4-0.50.4-0.40.9-0.9-0.9-0.7-1.01.10.7-0.71.1-1.21.1-1.2-1.1-1.30.6-1.3-0.90.91.3-1.5
Liver weight, right1.52.57.0-2.2-1.91.91.8-2.12.1-1.51.41.72.11.6-1.0-1.61.6-1.41.2-1.40.11.40.72.61.00.9-0.8-0.90.8
Locomotor activity0.60.91.41.01.1-1.1-1.01.0-1.01.0-1.0-1.0-1.0-0.91.01.2-1.21.2-0.91.1-0.5-0.9-0.8-0.6-1.0-0.10.10.6-0.9
Locomotor testing distance0.50.81.71.01.2-1.2-1.10.9-0.90.7-0.7-0.7-1.0-0.50.61.3-1.30.9-0.41.0-0.0-0.5-0.4-1.1-0.71.0-1.00.1-0.6
Locomotor testing rearing0.30.42.40.30.7-0.7-0.60.5-0.50.1-0.1-0.2-0.7-0.0-0.10.6-0.60.20.10.31.20.00.1-1.1-0.01.6-1.6-0.3-0.1
Locomotion in novel chamber0.20.21.30.20.4-0.4-0.30.3-0.30.0-0.00.0-0.30.2-0.30.5-0.5-0.00.20.20.60.30.2-0.60.11.2-1.1-0.50.0
Locomotion in novel chamber post-restriction1.72.04.2-1.6-1.91.91.9-1.51.5-1.41.41.51.91.3-1.2-2.12.1-1.51.1-1.70.31.11.11.11.3-0.10.1-0.81.3
Fecal boli incidents, locomotor time 10.30.30.70.70.6-0.6-0.90.5-0.50.6-0.6-0.6-0.5-0.50.50.8-0.80.5-0.40.7-0.2-0.3-0.3-0.4-0.30.2-0.30.2-0.1
Change in fecal boli incidents, locomotor task3.93.76.21.91.7-1.7-1.51.8-1.82.0-2.0-2.1-1.8-2.32.51.3-1.32.3-2.21.8-2.0-2.2-2.0-0.3-2.3-2.02.01.9-2.0
Time >=10cm from walls, locomotor time 11.51.53.7-1.2-1.01.01.2-0.80.8-1.01.01.21.91.2-0.9-1.01.0-1.31.3-1.31.01.51.3-0.11.31.4-1.5-1.61.6
Bouts of movement, locomotor time 11.81.92.81.71.5-1.5-1.51.7-1.71.5-1.5-1.5-1.3-1.51.31.4-1.41.3-1.31.4-1.1-1.3-1.1-1.0-1.3-1.51.41.0-0.9
Total resting periods, locomotor time 12.62.94.51.81.7-1.7-1.71.9-1.91.8-1.8-1.8-1.6-1.91.71.6-1.61.7-1.71.7-1.5-1.7-1.5-0.8-1.6-2.12.11.4-1.2
Rest time, locomotor task time 10.70.82.30.70.6-0.6-0.70.5-0.50.8-0.8-0.8-0.9-1.00.80.5-0.50.9-1.00.9-1.2-1.0-1.00.4-1.0-1.51.51.0-0.9
Distance moved, locomotor task time 11.11.23.6-1.0-0.80.81.1-0.90.9-1.01.01.11.21.0-1.1-0.80.8-1.11.1-1.11.01.21.10.11.01.9-1.9-1.10.8
Vertical activity count, locomotor time 12.82.97.9-1.5-1.21.21.5-1.41.4-1.61.61.71.81.9-1.9-1.11.1-1.81.8-1.51.91.91.7-0.11.62.8-2.8-1.91.4
Time >=10cm from walls, locomotor time 20.10.11.4-0.4-0.10.10.1-0.20.20.1-0.10.30.70.20.5-0.30.3-0.10.1-0.3-0.40.3-0.01.20.30.0-0.0-0.40.5
Bouts of movement, locomotor time 20.80.81.71.31.2-1.2-1.31.2-1.21.0-1.0-1.0-1.0-0.90.80.8-0.80.8-0.70.8-0.8-0.7-0.5-1.1-0.6-0.60.60.2-0.2
Total resting periods, locomotor time 20.30.41.00.90.9-0.9-1.00.9-0.90.7-0.7-0.5-0.6-0.50.50.5-0.50.4-0.30.4-0.5-0.2-0.2-0.9-0.2-0.10.0-0.20.2
Rest time, locomotor task time 20.10.10.50.20.2-0.2-0.20.3-0.30.4-0.4-0.30.0-0.40.50.1-0.10.2-0.30.2-0.7-0.3-0.40.5-0.3-0.40.40.30.0
Distance moved, locomotor task time 20.10.10.7-0.10.0-0.00.1-0.10.1-0.20.20.30.10.3-0.1-0.20.2-0.10.2-0.3-0.00.30.20.30.30.8-0.8-0.30.1
Vertical activity count, locomotor time 20.70.82.6-0.7-0.40.40.4-0.40.4-0.80.80.90.81.1-0.9-0.50.5-0.91.0-0.80.81.01.0-0.31.01.6-1.6-1.21.0
Light reinforcement 12.44.47.3-2.0-1.91.91.9-1.81.8-2.12.12.22.72.4-2.2-1.31.3-2.22.3-1.82.32.42.2-0.22.12.7-2.6-2.61.8
Light reinforcement 23.24.38.1-2.3-2.12.12.2-2.22.2-2.02.02.22.82.3-1.9-1.51.5-2.12.1-1.91.62.21.81.01.92.7-2.6-2.11.5
Bone: marrow area0.30.61.4-0.4-0.20.20.2-0.20.2-0.70.70.70.60.8-0.8-0.30.3-0.81.0-0.70.91.01.1-1.01.00.6-0.6-1.21.2
Bone: maximum diameter1.32.34.5-2.0-2.02.02.0-1.91.9-1.51.51.72.11.6-1.2-1.61.6-1.41.3-1.40.41.31.01.71.30.8-0.8-0.90.9
Bone: maximum force4.67.912.3-3.2-3.53.53.5-3.53.5-3.23.23.13.12.8-2.6-3.43.4-2.82.6-3.01.82.42.31.72.51.6-1.6-1.71.7
Bone: maximum moment4.98.413.8-3.3-3.73.73.7-3.73.7-3.33.33.13.12.9-2.8-3.53.5-2.82.6-3.01.92.42.31.82.41.7-1.7-1.51.5
Mean time between licks in bursts1.11.52.61.61.6-1.6-1.61.6-1.61.3-1.3-1.3-1.2-1.11.21.6-1.61.2-1.01.2-1.1-0.9-0.8-1.1-0.9-0.70.70.6-0.5
Mean num. licks in bursts0.20.31.30.2-0.10.10.1-0.20.20.1-0.1-0.4-0.8-0.50.2-0.20.20.4-0.50.30.1-0.8-0.50.2-0.6-0.90.81.1-0.9
Cd content in liver1.21.34.11.41.5-1.5-1.51.5-1.51.0-1.0-1.2-1.5-1.10.61.3-1.30.8-0.81.10.1-0.8-0.5-2.0-0.6-0.30.30.4-0.3
Co content in liver0.10.10.50.20.4-0.4-0.30.3-0.30.1-0.1-0.2-0.4-0.20.10.5-0.50.2-0.10.40.5-0.1-0.0-0.7-0.10.2-0.20.1-0.1
Cu content in liver0.40.52.0-0.1-0.30.30.3-0.30.30.3-0.3-0.4-0.4-0.60.5-0.20.20.7-0.70.5-0.6-1.0-1.01.4-0.9-0.70.61.4-1.2
Fe content in liver0.60.71.51.11.1-1.1-1.11.1-1.10.9-0.9-0.9-0.9-0.80.61.2-1.20.8-0.71.0-0.5-0.6-0.5-0.9-0.6-0.00.00.3-0.3
K content in liver2.92.94.3-2.0-1.81.81.7-1.61.6-1.81.81.92.12.0-1.5-1.51.5-1.81.8-1.81.41.91.60.81.81.3-1.2-1.71.7
Mg content in liver1.51.53.8-1.2-0.60.60.6-0.50.5-1.01.11.31.41.5-1.2-0.70.7-1.41.5-1.31.31.71.5-0.21.61.4-1.4-1.91.9
Mn content in liver0.20.21.1-0.7-0.60.60.6-0.50.5-0.30.30.50.60.3-0.0-0.60.6-0.30.3-0.4-0.10.30.11.00.20.2-0.2-0.20.1
Na content in liver0.00.00.4-0.2-0.10.10.1-0.10.10.1-0.10.00.30.00.10.1-0.10.1-0.10.1-0.40.0-0.20.6-0.20.00.00.0-0.3
Rb content in liver1.72.13.2-1.5-1.21.21.2-1.11.1-1.51.51.51.31.6-1.5-1.41.4-1.61.6-1.61.81.61.6-0.31.71.3-1.3-1.51.6
Se content in liver0.40.50.8-0.9-0.70.70.7-0.70.7-0.70.70.70.70.7-0.9-0.70.7-0.80.7-0.70.90.70.70.20.60.7-0.7-0.60.6
Sr content in liver1.61.43.51.00.5-0.5-0.50.4-0.41.1-1.1-1.2-1.1-1.41.10.7-0.71.3-1.51.3-1.5-1.6-1.60.7-1.6-1.41.41.9-1.9
Zn content in liver0.20.32.00.10.2-0.2-0.20.2-0.20.6-0.6-0.30.0-0.30.80.1-0.10.4-0.50.3-1.2-0.4-0.71.4-0.3-0.50.50.4-0.2
Bone: minimum diameter2.24.28.0-2.6-2.82.82.8-2.82.8-2.32.32.22.42.0-2.0-2.22.2-1.91.7-1.71.41.61.41.71.60.6-0.7-0.90.9
Time in familiar zone, hab. session 10.20.20.50.40.3-0.3-0.30.3-0.30.3-0.3-0.4-0.7-0.50.0-0.00.00.3-0.40.3-0.0-0.6-0.3-0.3-0.5-0.50.50.7-0.6
Time in novel zone, hab. session 10.10.10.3-0.3-0.20.20.2-0.20.2-0.20.20.30.40.40.0-0.00.0-0.20.3-0.30.20.40.30.10.40.3-0.3-0.50.4
Total zone transitions, hab. session 10.20.22.00.60.6-0.6-0.60.6-0.60.2-0.2-0.3-0.5-0.2-0.00.6-0.60.1-0.00.30.4-0.10.2-1.4-0.00.2-0.2-0.20.1
Total locomotion distance, hab. session 10.60.82.3-0.4-0.50.50.5-0.50.5-0.90.90.70.60.8-1.2-0.20.2-1.01.0-0.41.50.91.2-1.41.01.1-1.2-1.00.9
Locomotion velocity, hab. session 10.60.81.9-0.5-0.50.50.6-0.60.6-0.90.90.80.70.9-1.3-0.20.2-1.01.1-0.51.41.01.2-1.31.01.2-1.3-1.10.9
Time in familiar zone, hab. session 20.20.21.80.50.5-0.5-0.40.4-0.40.1-0.1-0.3-0.5-0.2-0.30.5-0.50.1-0.00.40.4-0.10.2-1.40.00.3-0.3-0.10.1
Time in novel zone, hab. session 20.10.10.40.00.2-0.2-0.20.2-0.20.3-0.3-0.1-0.0-0.10.60.1-0.10.2-0.2-0.0-0.5-0.1-0.30.6-0.2-0.30.30.0-0.1
Total zone transitions, hab. session 20.60.83.2-0.00.2-0.2-0.30.3-0.3-0.50.50.50.30.7-0.9-0.00.0-0.91.0-0.71.21.11.3-1.81.21.0-1.0-1.51.6
Total locomotion distance, hab. session 22.02.75.4-1.2-0.90.90.9-0.90.9-1.61.61.61.61.8-1.7-0.90.9-1.92.0-1.61.92.12.1-1.22.21.8-1.8-2.32.3
Locomotion velocity, hab. session 22.33.15.7-1.4-1.21.21.2-1.21.2-1.71.81.81.82.0-1.9-1.21.2-2.02.1-1.71.92.22.2-0.92.31.9-1.9-2.42.4
Novel to familiar place preference ratio1.21.22.6-1.4-1.61.61.6-1.61.6-1.21.20.90.70.7-1.0-1.51.5-0.80.6-0.91.30.30.41.30.4-0.0-0.00.3-0.3
Novelty place preference1.11.12.4-1.4-1.51.51.5-1.51.5-1.11.10.90.60.6-0.9-1.51.5-0.70.5-0.91.10.20.31.30.3-0.10.00.4-0.4
Time in novel zone, NPP test0.91.02.0-1.3-1.41.41.4-1.41.4-1.11.00.90.60.6-0.9-1.41.4-0.70.5-0.91.20.30.31.10.4-0.0-0.10.2-0.3
Total zone transitions, NPP test0.71.04.00.10.4-0.4-0.40.4-0.4-0.40.40.50.40.8-0.80.3-0.3-0.91.1-0.61.11.21.4-2.01.31.3-1.3-1.81.8
Total locomotion distance, NPP test1.92.66.2-0.9-0.60.60.5-0.50.5-1.41.41.51.41.7-1.8-0.50.5-1.82.0-1.42.02.12.2-1.82.12.0-2.1-2.52.4
Locomotion velocity, NPP test1.62.34.8-0.9-0.70.70.7-0.70.7-1.41.41.41.41.7-1.7-0.60.6-1.71.9-1.31.91.92.0-1.52.02.0-2.0-2.22.1
Intraocular pressure0.81.11.8-0.8-0.90.90.8-1.21.2-1.11.11.00.71.0-1.0-1.31.3-1.11.1-1.30.80.91.2-0.41.11.0-1.1-1.01.2
Delta distance traveled before/after self-admin0.40.42.10.20.5-0.5-0.30.4-0.4-0.10.10.2-0.20.3-0.10.1-0.1-0.20.5-0.41.10.40.7-1.40.61.4-1.4-0.70.8
Delta ambulatory time before/after self-admin0.50.62.00.71.1-1.1-1.01.0-1.00.5-0.5-0.4-0.9-0.20.50.6-0.60.30.00.10.6-0.10.2-1.30.21.4-1.4-0.40.6
Parametrial fat weight1.42.84.3-2.0-1.91.92.1-2.02.0-1.81.81.81.81.8-1.8-1.81.8-1.71.5-1.61.01.41.31.31.41.6-1.6-1.11.0
Pavlov. Cond. lever latency0.70.98.40.70.8-0.8-0.80.8-0.8-0.10.2-0.0-0.50.2-0.90.6-0.6-0.50.6-0.01.50.61.1-2.90.71.0-1.1-1.11.2
Pavlov. Cond. magazine entry latency0.81.03.8-1.1-1.51.51.5-1.51.5-0.80.80.70.70.4-0.5-1.51.5-0.30.1-0.6-0.3-0.1-0.21.9-0.1-0.70.80.8-0.9
Pavlov. Cond. change in total contacts0.50.62.20.0-0.20.20.2-0.20.20.3-0.3-0.5-0.6-0.70.5-0.00.00.8-0.80.6-0.4-1.0-1.01.0-1.0-1.11.11.5-1.5
Pavlov. Cond. index score1.31.76.8-1.7-1.91.91.9-1.91.9-1.21.11.21.50.9-0.7-1.71.7-0.70.5-1.1-0.10.50.22.60.4-0.20.20.2-0.4
Pavlov. Cond. latency score1.01.38.0-1.4-1.61.61.6-1.61.6-0.70.70.81.20.6-0.1-1.41.4-0.30.1-0.7-0.70.1-0.32.80.0-0.60.60.5-0.7
Pavlov. Cond. lever contacts0.40.54.5-0.8-0.80.80.8-0.80.8-0.20.20.40.80.20.2-0.60.60.0-0.1-0.3-0.7-0.0-0.42.1-0.1-0.50.50.4-0.6
Pavlov. Cond. magazine entry number0.80.94.30.71.2-1.2-1.21.2-1.20.4-0.4-0.2-0.30.10.01.2-1.2-0.10.40.20.70.70.7-2.10.61.2-1.2-1.41.5
Pavlov. Cond. intertrial magazine entries1.01.22.6-0.8-0.70.70.7-0.70.7-1.11.11.10.91.1-1.4-0.80.8-1.31.3-1.01.21.31.3-0.61.41.4-1.4-1.31.6
Pavlov. Cond. lever-magazine prob. diff.1.41.76.1-1.7-2.02.02.0-2.02.0-1.21.21.21.40.9-0.8-1.71.7-0.80.6-1.10.10.50.22.50.4-0.00.10.2-0.4
Pavlov. Cond. response bias0.70.95.2-0.9-1.31.31.3-1.31.3-0.50.50.40.60.1-0.1-1.21.2-0.0-0.2-0.4-0.6-0.3-0.52.3-0.4-0.91.01.0-1.1
Pavlov. Cond. lever latency1.62.25.21.11.0-1.0-1.01.1-1.11.6-1.6-1.4-0.9-1.61.91.1-1.11.6-1.71.4-2.3-1.6-1.81.2-1.7-1.91.91.6-1.5
Pavlov. Cond. magazine entry latency0.70.96.11.11.2-1.2-1.21.2-1.20.5-0.5-0.6-1.0-0.4-0.11.2-1.20.2-0.00.60.9-0.00.3-2.50.00.6-0.6-0.40.4
Pavlov. Cond. change in total contacts0.50.74.60.20.2-0.2-0.20.2-0.2-0.50.50.3-0.20.5-1.00.2-0.2-0.50.7-0.21.70.61.0-2.20.71.4-1.4-0.90.7
Pavlov. Cond. index score0.50.74.60.20.2-0.2-0.20.1-0.1-0.50.60.3-0.30.5-1.10.2-0.2-0.60.8-0.31.80.61.0-2.20.71.2-1.3-0.80.7
Pavlov. Cond. latency score0.60.84.1-0.00.1-0.1-0.1-0.00.0-0.60.70.4-0.10.7-1.10.0-0.0-0.70.9-0.41.90.81.2-2.00.91.4-1.4-1.00.9
Pavlov. Cond. lever contacts2.23.06.1-1.4-1.31.31.3-1.31.3-1.81.91.71.31.9-2.1-1.31.3-1.92.0-1.72.51.92.1-1.12.02.1-2.1-1.91.8
Pavlov. Cond. magazine entry number0.60.76.5-0.9-1.01.01.0-0.90.9-0.20.20.40.70.10.5-1.01.00.0-0.2-0.4-1.4-0.2-0.62.6-0.2-0.90.90.6-0.5
Pavlov. Cond. intertrial magazine entries1.62.03.3-1.7-1.61.61.6-1.61.6-1.51.51.61.41.5-1.3-1.81.8-1.51.4-1.80.91.31.21.11.50.5-0.5-1.01.3
Pavlov. Cond. lever-magazine prob. diff.0.50.65.30.30.3-0.3-0.30.2-0.2-0.40.40.2-0.40.4-1.00.3-0.3-0.50.7-0.11.70.51.0-2.30.61.1-1.2-0.70.6
Pavlov. Cond. response bias0.91.34.0-0.5-0.40.40.4-0.50.5-1.01.10.90.41.1-1.4-0.50.5-1.21.3-0.92.01.21.5-1.71.21.7-1.7-1.31.2
Time in closed arm before self-admin0.91.04.61.10.3-0.3-0.30.8-0.80.8-0.8-0.9-0.2-1.20.90.4-0.40.8-1.10.8-1.3-0.9-0.8-0.6-1.1-2.12.11.1-1.1
Time in closed arm after self-admin2.72.88.11.21.2-1.2-1.11.3-1.31.6-1.6-1.6-1.3-1.71.70.9-0.91.6-1.91.5-2.2-1.8-1.91.3-1.8-2.82.81.9-1.5
Time in open arm before self-admin0.30.32.3-0.60.3-0.3-0.3-0.40.40.1-0.10.3-0.10.40.40.2-0.20.10.2-0.10.00.3-0.11.50.31.5-1.5-0.40.5
Time in open arm after self-admin0.40.54.3-0.10.1-0.1-0.0-0.20.2-0.20.20.20.30.4-0.20.3-0.3-0.20.5-0.10.70.50.5-0.90.42.1-2.0-0.80.3
Bone: periosteal estimation1.93.95.7-2.3-2.42.42.4-2.42.4-2.22.22.22.32.1-2.0-2.12.1-2.01.9-2.01.41.91.81.11.91.1-1.1-1.41.4
Bone: periosteal perimeter1.62.68.2-2.0-2.42.42.4-2.42.4-1.51.51.62.01.3-1.0-2.02.0-1.10.8-1.2-0.20.80.42.90.7-0.10.1-0.00.0
Bone: post-yield work0.20.30.8-0.2-0.00.00.0-0.10.1-0.40.40.40.40.6-0.5-0.20.2-0.60.6-0.50.50.70.7-0.60.70.6-0.6-0.90.9
Progressive ratio test 1 active lever presses1.41.52.6-1.5-1.41.41.3-1.21.2-1.31.31.31.61.4-1.0-1.21.2-1.21.2-1.40.91.21.10.61.21.1-1.0-1.01.2
Progressive ratio test 1 breakpoint1.71.83.2-1.6-1.61.61.5-1.21.2-1.41.41.51.81.5-1.3-1.41.4-1.41.3-1.51.11.31.30.61.30.9-0.8-1.11.3
Progressive ratio test 1 inactive lever presses3.03.34.4-2.1-2.12.12.0-1.61.6-2.12.12.01.82.1-2.0-1.81.8-2.01.9-2.01.81.81.80.41.91.3-1.2-1.51.5
Progressive ratio test 2 active lever presses0.40.40.9-0.9-0.70.70.5-0.60.6-0.60.60.60.60.6-0.4-0.90.9-0.60.5-0.70.40.60.40.90.70.6-0.6-0.20.6
Progressive ratio test 2 breakpoint0.70.71.2-1.1-0.80.80.7-0.70.7-0.80.80.90.80.8-0.6-1.11.1-0.90.8-0.90.60.90.70.81.01.0-1.0-0.60.9
Progressive ratio test 2 inactive lever presses0.20.30.7-0.8-0.60.60.6-0.60.6-0.60.60.50.20.5-0.4-0.80.8-0.40.4-0.60.40.30.20.80.40.4-0.4-0.10.3
Incentive Sensitization - Responses0.10.10.6-0.4-0.40.40.3-0.30.3-0.30.30.30.20.2-0.3-0.80.8-0.40.2-0.4-0.10.30.20.50.3-0.00.0-0.10.4
Incentive Sensitization - Breakpoint0.10.10.4-0.3-0.30.30.2-0.20.2-0.20.20.20.10.1-0.2-0.60.6-0.30.1-0.3-0.10.20.10.60.3-0.10.10.00.3
Sum of active levers in priming session hrs 5-60.40.42.30.1-0.50.50.5-0.70.7-0.60.60.1-0.20.0-0.3-0.60.6-0.10.1-0.21.0-0.20.3-1.50.0-1.21.10.3-0.5
Progressive ratio0.40.51.40.70.8-0.8-0.90.8-0.80.7-0.7-0.8-1.2-0.60.40.7-0.70.6-0.60.7-0.1-0.8-0.6-0.4-0.6-0.70.70.8-0.5
Food seeking constrained by brief footshock0.40.51.20.70.5-0.5-0.50.5-0.50.7-0.7-0.8-0.9-0.80.50.7-0.70.8-0.80.9-0.2-1.0-0.8-0.0-0.8-0.30.21.1-0.9
Seeking ratio, punishment vs. effort0.20.31.1-0.3-0.50.50.6-0.50.5-0.50.50.50.70.3-0.3-0.40.4-0.50.4-0.40.20.50.5-0.10.51.1-1.1-0.50.4
Retroperitoneal fat weight4.615.120.7-4.4-4.54.54.6-4.44.4-4.34.34.24.44.1-4.4-3.83.8-4.03.8-3.73.73.73.51.53.63.0-3.1-2.82.4
Reaction time number correct3.34.711.1-1.1-0.70.70.8-0.70.7-1.91.91.91.62.3-2.3-0.70.7-2.32.7-2.13.12.73.0-2.62.53.2-3.2-3.32.8
Reaction time mean minus median0.40.61.20.40.4-0.4-0.40.3-0.30.7-0.7-0.7-0.4-0.60.90.6-0.60.8-0.90.8-1.0-0.8-1.01.1-0.9-0.90.90.9-1.0
Reaction time mean minus median AUC0.10.12.1-0.20.1-0.1-0.0-0.10.10.2-0.20.00.10.10.30.2-0.20.1-0.20.1-0.6-0.0-0.41.4-0.2-0.00.00.1-0.3
Reaction time num false alarms0.30.41.01.00.5-0.5-0.50.7-0.70.5-0.5-0.6-0.6-0.60.50.5-0.50.5-0.50.7-0.6-0.6-0.3-0.8-0.5-0.80.80.5-0.5
Reaction time num false alarms AUC0.50.71.61.30.9-0.9-0.91.0-1.00.8-0.8-0.8-0.9-0.70.70.9-0.90.7-0.60.9-0.8-0.7-0.4-0.9-0.6-0.80.80.5-0.4
Reaction time trials correct on left3.34.711.1-1.1-0.70.70.8-0.70.7-1.91.91.91.62.3-2.3-0.70.7-2.32.7-2.13.12.73.0-2.62.53.2-3.2-3.32.8
Reaction time trials on left3.44.911.5-1.2-0.70.70.8-0.70.7-1.91.92.01.62.4-2.3-0.70.7-2.32.7-2.13.12.83.0-2.62.63.3-3.2-3.42.9
Reaction time mean0.40.61.1-0.8-0.80.80.7-0.70.7-0.80.80.70.80.9-0.9-0.50.5-0.80.7-0.60.90.80.70.00.61.1-1.1-0.70.4
Reaction time mean AUC0.70.92.3-0.9-0.80.80.7-0.80.8-0.90.90.91.01.1-1.0-0.40.4-0.91.0-0.81.11.11.0-0.20.81.5-1.5-1.00.8
Median of all reaction times0.60.91.7-0.9-0.90.90.8-0.80.8-1.01.00.90.91.1-1.1-0.50.5-1.01.0-0.91.21.01.0-0.40.81.3-1.3-0.90.7
Reaction time omissions0.30.41.0-0.6-0.40.40.5-0.50.5-0.70.70.70.41.0-0.8-0.20.2-0.60.8-0.50.70.80.8-0.10.70.4-0.4-0.80.6
Reaction time false alarm rate2.02.85.41.71.1-1.1-1.21.3-1.31.6-1.6-1.7-1.5-1.81.81.1-1.11.7-1.91.8-2.2-1.9-1.80.4-1.8-2.32.32.1-1.8
Reaction time premature initiation rate1.31.83.71.81.6-1.6-1.61.4-1.41.3-1.3-1.5-1.9-1.51.31.2-1.21.4-1.21.3-0.8-1.3-1.0-1.3-1.1-1.11.01.0-0.7
Reaction time premature initiations0.50.76.51.01.1-1.1-0.90.8-0.80.2-0.2-0.3-0.8-0.1-0.10.7-0.7-0.00.30.01.00.30.7-2.50.40.8-0.9-0.91.0
Std. dev. reaction times0.20.20.60.50.5-0.5-0.60.6-0.60.5-0.5-0.5-0.4-0.30.40.8-0.80.4-0.40.5-0.3-0.3-0.3-0.3-0.5-0.20.20.1-0.3
Reaction time trials completed3.44.911.5-1.2-0.70.70.8-0.70.7-1.91.92.01.62.4-2.3-0.70.7-2.32.7-2.13.12.83.0-2.62.63.3-3.2-3.42.9
Reaction time trials AUC3.55.111.6-1.2-0.80.80.9-0.80.8-1.92.02.01.72.4-2.4-0.70.7-2.32.7-2.13.22.83.0-2.62.63.4-3.3-3.42.9
Run reversals in cocaine runway, females0.50.54.90.80.5-0.5-0.40.6-0.60.2-0.2-0.30.1-0.20.20.7-0.70.20.10.10.20.20.5-2.2-0.11.2-1.2-0.60.6
Run reversals in cocaine runway, males0.50.52.9-0.9-0.90.90.8-1.11.1-0.50.40.40.50.2-0.2-0.90.9-0.2-0.0-0.3-0.2-0.0-0.31.7-0.1-0.80.70.4-0.5
Latency to leave start box in cocaine runway0.10.10.50.50.3-0.3-0.50.5-0.50.3-0.3-0.3-0.2-0.20.20.1-0.10.1-0.10.0-0.2-0.10.0-0.7-0.00.6-0.5-0.00.5
Latency to leave start box in cocaine runway, F0.30.32.20.20.2-0.2-0.40.2-0.2-0.00.00.20.20.40.10.1-0.1-0.20.4-0.30.20.50.5-0.70.51.5-1.5-0.71.1
Latency to leave start box in cocaine runway, M0.00.00.20.0-0.20.20.10.2-0.20.1-0.1-0.10.0-0.3-0.1-0.40.4-0.1-0.2-0.0-0.3-0.2-0.20.3-0.1-0.10.10.2-0.0
Std. dev. time between licks in bursts3.23.87.5-1.3-1.11.11.1-1.11.1-1.81.91.92.02.2-2.2-1.11.1-2.22.3-1.92.12.52.5-1.42.32.7-2.6-2.72.5
Total sessions with >9 infusions0.10.10.40.10.4-0.4-0.50.6-0.60.5-0.5-0.2-0.2-0.10.30.4-0.40.2-0.20.2-0.5-0.2-0.30.7-0.3-0.10.10.10.1
Short access day 1 total inactive lever presses0.30.41.6-0.5-0.10.1-0.0-0.30.3-0.40.40.60.40.8-0.0-0.30.3-0.30.8-0.60.10.80.60.40.81.3-1.2-0.71.0
Short access day 10 total inactive lever presses2.32.55.2-2.1-2.02.01.9-1.71.7-1.81.81.71.21.4-1.7-2.32.3-1.61.4-1.81.51.31.21.11.30.8-0.7-0.80.9
Short access day 1 total infusions1.41.52.51.21.3-1.3-1.51.6-1.61.4-1.4-1.2-1.1-1.01.21.6-1.61.2-1.11.3-1.0-1.1-1.1-0.2-1.1-0.70.70.9-0.9
Short access day 10 total infusions0.40.40.8-0.9-0.90.90.7-0.70.7-0.70.70.60.80.6-0.5-0.90.9-0.70.5-0.70.50.60.40.70.6-0.00.0-0.20.3
Short access total infusions0.00.00.2-0.1-0.10.1-0.10.3-0.30.1-0.10.00.20.1-0.0-0.00.0-0.1-0.0-0.1-0.1-0.0-0.00.2-0.0-0.40.40.10.1
Short access day 1 locomotion0.80.81.30.50.7-0.7-0.71.1-1.11.0-1.0-0.8-0.7-0.81.10.9-0.91.0-0.90.9-0.9-0.9-1.11.0-0.9-0.90.91.0-0.9
Short access day 10 total locomotion0.60.61.30.40.5-0.5-0.60.5-0.50.7-0.7-0.7-0.8-0.80.90.6-0.60.9-0.90.8-1.0-1.0-1.11.1-0.9-0.70.71.1-1.0
Short access total locomotion0.90.91.60.50.6-0.6-0.91.0-1.01.0-1.0-0.9-0.8-0.91.20.7-0.71.0-1.00.9-1.3-1.0-1.21.2-0.8-1.01.01.2-0.7
One hour access (0.3 mA shock)1.82.12.8-1.7-1.61.61.5-1.51.5-1.51.51.51.51.5-1.5-1.61.6-1.61.4-1.61.41.41.40.41.51.3-1.3-1.11.4
Compulsive drug intake0.60.61.5-0.5-0.80.80.9-0.90.9-1.01.00.80.70.9-1.2-0.60.6-1.00.9-0.71.00.70.9-0.60.80.2-0.2-0.70.7
One hour access (shock baseline)0.50.62.2-1.1-0.50.50.5-0.60.6-0.60.60.80.80.7-0.3-0.70.7-0.70.7-0.80.30.80.60.90.81.5-1.4-0.70.8
Social response proportion0.20.20.70.50.9-0.9-0.70.6-0.60.3-0.3-0.3-0.7-0.30.10.7-0.70.2-0.00.30.4-0.00.0-0.6-0.00.3-0.3-0.10.0
Social responses0.10.11.0-0.00.2-0.2-0.10.2-0.20.0-0.00.10.20.1-0.40.6-0.6-0.10.20.20.50.20.1-0.20.11.0-1.0-0.40.1
Social time0.10.10.50.00.2-0.2-0.10.2-0.20.0-0.00.00.10.0-0.30.3-0.3-0.20.20.20.50.20.2-0.70.00.5-0.6-0.30.1
Soleus weight1.44.05.8-2.3-2.32.32.3-2.32.3-2.12.12.22.42.1-1.8-2.12.1-2.11.9-2.11.12.01.71.41.91.7-1.7-1.61.5
Bone: stiffness0.81.21.7-1.2-1.31.31.2-1.31.3-1.21.21.31.31.2-0.9-1.31.3-1.11.1-1.20.51.11.10.61.10.8-0.8-0.90.9
Tibialis anterior weight0.10.51.4-0.6-0.30.30.4-0.30.3-0.60.60.70.80.8-0.7-0.40.4-0.90.9-0.80.51.00.9-0.30.90.5-0.5-1.11.2
Time to tail flick, vehicle, before self-admin0.20.20.4-0.5-0.50.50.3-0.50.5-0.30.30.40.60.40.1-0.30.3-0.30.4-0.40.20.50.40.10.50.6-0.5-0.50.6
Time to tail flick, vehicle, after self-admin1.71.83.31.61.7-1.7-1.61.5-1.51.6-1.6-1.4-0.9-1.31.51.6-1.61.3-1.21.4-1.8-1.0-1.2-0.1-1.2-0.80.80.8-0.6
Time to tail flick, test, before self-admin0.10.10.50.10.3-0.3-0.10.1-0.10.1-0.1-0.1-0.7-0.20.4-0.60.60.2-0.3-0.3-0.4-0.4-0.30.70.0-0.50.40.60.0
Time to tail flick, test, after self-admin0.30.30.80.20.8-0.8-0.80.5-0.50.6-0.6-0.5-0.9-0.30.60.7-0.70.6-0.40.6-0.1-0.5-0.70.8-0.5-0.00.00.5-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.40.40.7-0.7-0.60.5-0.50.3-0.3-0.1-0.4-0.0-0.20.4-0.40.00.00.20.00.00.0-0.30.10.4-0.5-0.20.2
Delta time to tail flick, test, before/after SA0.70.71.30.60.8-0.8-0.80.6-0.60.9-0.9-0.9-0.7-0.80.81.1-1.11.0-0.81.1-0.3-0.7-0.90.0-1.1-0.30.30.7-1.1
Tibia length5.014.027.7-4.7-5.35.35.2-5.25.2-3.93.83.84.13.3-2.7-5.15.1-3.02.6-3.71.12.31.84.82.21.7-1.7-0.80.7
Ambulatory time before self-admin1.21.33.0-1.4-1.71.71.7-1.61.6-1.31.31.11.51.0-1.3-1.11.1-1.00.8-0.71.00.70.70.60.4-0.50.6-0.4-0.3
Ambulatory time after self-admin0.60.61.8-0.8-0.70.70.8-0.70.7-0.90.90.80.80.8-0.9-0.60.6-0.80.8-0.71.40.70.9-0.60.70.8-0.8-0.90.4
Bone: tissue strength2.32.22.8-1.5-1.41.41.4-1.41.4-1.51.51.61.61.6-1.5-1.31.3-1.61.6-1.51.61.61.50.11.61.7-1.7-1.51.5
Total heroin consumption0.30.42.60.30.2-0.2-0.0-0.20.20.2-0.2-0.5-0.5-0.40.20.7-0.70.7-0.60.90.2-0.8-0.70.0-1.0-0.60.60.7-1.6
Bone: trabecular number0.00.00.2-0.2-0.10.10.1-0.10.1-0.10.10.20.20.2-0.2-0.10.1-0.20.1-0.2-0.20.20.10.30.10.5-0.5-0.20.3
Bone: trabecular spacing2.02.76.8-1.0-0.70.70.7-0.70.7-1.61.61.51.31.7-1.9-0.70.7-1.82.0-1.42.62.02.2-1.82.11.7-1.7-2.32.2
Bone: trabecular thickness0.50.62.20.0-0.40.40.4-0.40.40.3-0.3-0.4-0.4-0.60.6-0.30.30.6-0.90.4-1.1-1.0-1.01.5-1.0-1.11.11.5-1.4
Bone: trabecular tissue density0.71.01.61.31.2-1.2-1.21.2-1.21.1-1.1-1.1-1.0-1.01.11.2-1.21.0-0.91.0-1.1-0.8-0.8-0.6-0.8-0.70.80.6-0.7
Water consumed over 24 hours0.50.61.40.20.3-0.3-0.30.3-0.30.7-0.7-0.7-0.6-0.80.90.4-0.40.8-0.90.8-0.7-0.8-1.11.0-1.0-1.21.21.1-1.2
Number of responses in last shaping day1.11.12.2-1.2-0.90.91.0-1.11.1-1.21.21.30.91.5-1.4-0.70.7-1.11.2-1.00.71.10.91.30.91.2-1.2-0.90.6