Hub : Genes

Nploc4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio NM_080577.2 0.02 0.01 2.8e-04 0.02 0.02 0.02 0.02 1.2e-04 1.3e-04 3.3e-04 2.9e-04
2 NAcc isoform ratio XM_039085086.2 0.02 0.01 5.6e-04 0.02 0.02 0.02 0.02 2.0e-04 2.4e-04 5.7e-04 5.8e-04
3 Liver gene expression Nploc4 0.04 0.03 1.9e-04 0.03 0.03 0.01 0.02 2.5e-04 8.1e-04 1.3e-02 1.3e-03
4 Brain isoform ratio NM_080577.2 0.05 0.03 8.5e-06 0.06 0.06 0.06 0.06 4.7e-06 2.1e-06 4.9e-06 5.1e-06
5 Brain isoform ratio XM_039085086.2 0.05 0.03 8.4e-06 0.06 0.06 0.06 0.06 4.3e-06 2.1e-06 5.4e-06 5.9e-06
6 Brain gene expression Nploc4 0.56 0.13 0.0e+00 0.59 0.61 0.61 0.61 3.4e-67 3.3e-72 1.1e-71 1.9e-71
7 IL gene expression Nploc4 0.29 0.16 1.0e-04 0.08 0.1 0.1 0.11 6.4e-03 2.8e-03 1.9e-03 1.7e-03
8 PL isoform ratio NM_080577.2 0.04 0.03 1.5e-04 0.04 0.04 0.03 0.04 2.2e-05 8.9e-05 1.9e-04 3.9e-05
9 PL isoform ratio XM_039085086.2 0.04 0.03 1.3e-04 0.04 0.04 0.03 0.04 1.8e-05 9.2e-05 2.5e-04 2.5e-05
10 Brain alternative polyA XM_039085086.2 0.04 0.03 1.3e-04 0.03 0.04 0.04 0.04 1.1e-03 5.0e-05 1.1e-04 7.9e-05
11 PL alternative polyA XM_039085086.2 0.04 0.04 4.9e-04 0.02 0.03 0.03 0.03 3.7e-03 2.0e-04 3.7e-04 3.6e-04
12 Brain alternative polyA NM_080577.2 0.04 0.03 1.3e-04 0.03 0.04 0.04 0.04 1.1e-03 4.7e-05 1.1e-04 7.5e-05
13 BLA gene expression Nploc4 0.49 0.15 0.0e+00 0.38 0.43 0.43 0.43 2.1e-21 1.3e-24 1.1e-24 1.0e-24
14 LHb gene expression Nploc4 0.49 0.19 1.8e-07 0.14 0.05 0.18 0.09 4.1e-04 2.9e-02 4.2e-05 3.3e-03
15 PL alternative polyA NM_080577.2 0.04 0.04 5.4e-04 0.02 0.03 0.03 0.03 4.8e-03 2.9e-04 4.1e-04 5.9e-04
16 pVTA gene expression Nploc4 0.54 0.13 0.0e+00 0.27 0.34 0.36 0.36 4.7e-22 1.6e-28 1.2e-29 7.7e-30
17 Brain mRNA stability Nploc4 0.33 0.18 0.0e+00 0.22 0.27 0.28 0.27 9.0e-21 5.3e-25 9.8e-26 1.2e-25
18 PL gene expression Nploc4 0.26 0.09 0.0e+00 0.27 0.4 0.39 0.39 9.4e-30 6.9e-46 1.5e-44 6.8e-45
19 BLA mRNA stability Nploc4 0.1 0.06 3.8e-05 0.07 0.07 0.08 0.09 2.2e-04 1.7e-04 7.4e-05 2.0e-05
20 PL mRNA stability Nploc4 0.08 0.05 6.2e-10 0.07 0.09 0.09 0.09 7.8e-08 2.8e-10 9.7e-10 6.1e-10
21 IC gene expression Nploc4 0.45 0.13 7.1e-15 0.26 0.3 0.28 0.29 1.9e-11 3.1e-13 2.0e-12 1.8e-12
22 NAcc gene expression Nploc4 0.16 0.07 0.0e+00 0.17 0.18 0.18 0.18 2.5e-25 6.6e-27 3.6e-26 2.7e-26
23 pVTA mRNA stability Nploc4 0.05 0.04 8.3e-04 0.04 0.03 0.02 0.03 6.4e-04 1.9e-03 1.2e-02 1.2e-03
24 Adipose mRNA stability Nploc4 0.05 0.04 3.0e-05 0.04 0.04 0.04 0.04 2.4e-05 8.3e-05 3.3e-05 6.5e-05
25 OFC mRNA stability Nploc4 0.21 0.12 1.0e-03 0.12 0.05 0.07 0.13 7.6e-04 2.8e-02 9.8e-03 6.1e-04
26 OFC gene expression Nploc4 0.53 0.17 1.2e-09 0.29 0.16 0.31 0.29 1.3e-07 1.6e-04 3.8e-08 1.1e-07
27 NAcc mRNA stability Nploc4 0.06 0.04 5.3e-08 0.05 0.05 0.04 0.05 1.1e-08 3.5e-08 3.8e-07 6.8e-08
28 RMTg gene expression Nploc4 0.23 0.12 1.6e-04 0.12 0.16 0.19 0.13 4.3e-04 6.3e-05 1.2e-05 2.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
Bone: apparent density0.30.50.70.7-0.7-0.70.6-0.60.70.70.7-0.7-0.8-0.80.80.70.80.80.80.80.80.80.80.80.80.70.00.70.70.9-0.6
Area under the delay curve1.21.42.7-1.61.61.5-1.51.5-1.5-1.2-1.21.21.21.2-1.2-1.2-1.1-1.1-1.2-1.3-1.1-0.7-1.0-1.0-1.0-1.01.4-0.9-1.0-0.60.1
BMI with tail0.93.06.81.6-1.6-1.71.5-1.51.51.51.6-1.6-1.8-1.71.91.71.81.71.81.71.81.71.71.71.62.10.72.12.61.3-1.8
BMI without tail3.310.012.53.3-3.3-3.43.3-3.23.23.43.1-3.1-3.5-3.33.53.13.33.23.33.33.43.13.23.23.03.1-0.22.93.52.6-3.0
Body weight2.511.015.94.0-4.0-4.03.9-3.93.83.34.0-4.0-3.6-3.53.63.03.13.33.53.33.42.73.03.02.82.8-2.02.63.41.9-2.0
Weight adjusted by age2.03.14.91.8-1.8-1.92.1-2.11.91.52.2-2.2-1.9-2.01.91.71.71.91.61.81.71.31.61.61.51.8-1.41.91.70.8-0.3
Bone surface0.10.21.30.6-0.6-0.60.5-0.50.60.30.6-0.6-0.3-0.30.30.00.20.30.40.40.30.20.20.30.3-0.3-1.1-0.30.00.20.4
Bone volume0.20.40.60.8-0.8-0.80.7-0.70.70.60.7-0.7-0.6-0.60.60.40.60.60.60.60.60.50.60.60.60.3-0.60.20.30.5-0.1
Breakpoint value in progressive ratio session0.20.20.90.6-0.6-0.50.8-0.80.20.10.7-0.7-0.4-0.10.40.3-0.1-0.00.00.00.1-0.2-0.2-0.2-0.40.80.10.70.9-0.60.5
Number of licking bursts0.20.30.80.3-0.3-0.50.3-0.30.70.50.4-0.4-0.5-0.60.50.70.60.70.80.70.60.60.70.70.8-0.1-0.4-0.00.20.9-0.1
Context. condit. distance diff. score2.32.85.21.0-1.0-1.00.9-0.91.21.51.0-1.0-1.7-1.81.72.12.01.91.91.91.82.22.02.12.12.21.22.01.72.3-0.8
Locomotion velocity, session 14.24.66.3-2.02.02.0-1.81.8-2.1-2.0-2.02.02.22.4-2.2-2.5-2.3-2.4-2.3-2.3-2.3-2.3-2.3-2.4-2.3-2.2-0.1-2.1-2.3-2.31.6
Locomotion distance, session 11.21.63.6-1.81.81.9-1.91.9-1.7-1.3-1.81.81.21.1-1.2-0.7-0.7-0.9-1.0-1.0-1.0-0.5-0.7-0.7-0.6-0.41.9-0.3-0.8-0.00.7
Locomotion velocity, session 25.26.07.6-2.72.72.8-2.72.7-2.6-2.6-2.72.72.72.6-2.7-2.4-2.4-2.5-2.5-2.5-2.6-2.3-2.3-2.3-2.2-2.50.6-2.3-2.4-1.82.1
Locomotion distance, session 20.20.21.3-0.70.70.7-0.70.6-0.4-0.1-0.60.60.10.0-0.10.30.20.1-0.00.10.00.40.30.20.30.31.10.50.30.8-0.0
Locomotion velocity, session 32.42.83.5-1.61.61.7-1.61.7-1.8-1.9-1.61.61.81.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.8-1.7-1.50.4-1.5-1.4-1.51.5
Locomotion distance, session 33.03.34.7-2.12.12.1-2.12.1-2.2-2.1-2.12.11.91.9-1.9-1.6-1.7-1.8-1.8-1.8-1.8-1.5-1.7-1.6-1.6-1.21.3-1.4-1.5-1.21.6
Stereotopy head waving bouts, day 31.01.11.8-0.90.90.9-0.90.9-0.9-1.1-0.90.91.11.1-1.2-1.1-1.2-1.1-1.1-1.2-1.1-1.2-1.2-1.1-1.1-1.3-0.3-1.2-1.2-0.90.8
Stereotopy head waving duration, day 30.50.60.9-0.80.80.8-0.80.8-0.8-0.8-0.80.80.90.8-0.9-0.7-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.7-1.0-0.0-0.8-0.9-0.50.7
Locomotion velocity, session 70.40.40.9-0.80.80.9-0.90.9-0.9-0.8-0.80.80.70.6-0.7-0.4-0.5-0.6-0.6-0.5-0.6-0.4-0.5-0.5-0.4-0.20.9-0.0-0.2-0.00.7
Locomotion distance, session 71.01.36.9-1.71.71.7-1.81.8-1.5-1.0-1.71.70.90.7-0.8-0.1-0.2-0.5-0.6-0.5-0.60.2-0.3-0.2-0.10.32.60.5-0.20.70.7
Stereotopy head waving bouts, day 70.20.20.50.7-0.7-0.60.6-0.60.50.50.5-0.5-0.6-0.50.60.40.40.40.40.40.50.30.40.40.30.5-0.10.10.30.3-0.2
Stereotopy head waving duration, day 70.20.30.80.7-0.7-0.70.6-0.60.70.40.6-0.6-0.5-0.50.50.40.30.50.50.50.50.30.40.40.40.0-0.9-0.20.10.30.2
Locomotion velocity, session 80.30.32.1-0.60.60.6-0.60.6-0.30.1-0.60.6-0.1-0.20.10.60.50.30.20.20.20.70.50.50.60.61.50.60.31.1-0.0
Locomotion distance, session 82.53.68.40.6-0.6-0.60.5-0.51.01.60.6-0.6-1.7-1.91.72.42.42.12.02.12.02.72.32.42.52.62.22.52.22.9-1.2
Degree of sensitization distance1.61.62.60.9-0.9-0.90.9-0.91.11.30.9-0.9-1.3-1.41.31.61.51.41.41.41.41.61.51.51.51.40.41.61.41.6-1.1
Degree of sensitization stereotypy0.50.61.10.8-0.8-0.80.8-0.80.70.80.7-0.7-0.9-0.80.90.80.80.80.80.80.90.80.80.80.71.00.20.50.70.6-0.4
Conditioned locomotion5.46.37.42.6-2.6-2.52.4-2.42.62.72.5-2.5-2.7-2.72.72.62.72.72.72.62.72.62.62.62.62.4-0.32.32.32.3-2.3
Cocaine response after cond. corrected0.20.30.9-0.40.40.4-0.20.3-0.6-0.4-0.40.40.40.7-0.4-0.7-0.6-0.7-0.7-0.7-0.5-0.7-0.7-0.7-0.80.00.7-0.1-0.0-0.9-0.0
Cocaine response after cond. not corrected0.80.91.3-1.01.00.9-0.80.8-1.1-0.9-1.01.00.91.1-0.9-1.1-1.0-1.1-1.1-1.1-1.0-1.0-1.0-1.1-1.1-0.50.8-0.6-0.5-1.00.2
Cocaine response before conditioning0.40.51.1-1.01.00.9-1.11.0-0.7-0.7-1.01.00.80.5-0.8-0.4-0.4-0.4-0.4-0.4-0.6-0.3-0.4-0.3-0.2-0.70.3-0.5-0.70.20.6
Saline control response2.63.54.92.1-2.1-2.12.1-2.12.22.12.1-2.1-2.0-2.02.01.71.92.02.02.02.01.71.91.81.81.3-0.91.41.61.5-1.3
Bone: connectivity density0.10.21.20.2-0.2-0.1-0.00.00.40.40.1-0.1-0.3-0.50.30.50.60.50.60.50.50.60.60.70.80.10.00.20.21.1-0.0
Bone: cortical apparent density2.43.34.8-2.22.22.1-2.12.1-2.2-2.0-2.12.11.91.9-1.9-1.6-1.7-1.8-1.8-1.8-1.9-1.5-1.7-1.7-1.6-1.21.4-1.1-1.5-1.31.2
Bone: cortical area3.75.710.53.2-3.2-3.23.2-3.23.02.53.1-3.1-2.5-2.42.51.71.92.22.42.32.31.61.91.91.81.4-2.51.32.11.1-1.3
Bone: cortical porosity0.70.72.90.6-0.6-0.50.7-0.60.1-0.30.6-0.60.30.6-0.3-1.1-1.0-0.8-0.7-0.8-0.6-1.3-1.0-1.1-1.2-0.8-1.6-0.7-0.3-1.70.7
Bone: cortical porosity0.50.52.61.0-1.0-0.91.1-1.00.50.21.0-1.0-0.20.10.2-0.6-0.5-0.3-0.3-0.3-0.2-0.8-0.5-0.6-0.8-0.3-1.6-0.30.1-1.30.3
Bone: cortical thickness2.44.08.62.9-2.9-2.92.9-2.92.62.12.8-2.8-2.0-1.82.01.21.31.51.81.71.70.91.21.21.00.8-2.70.81.60.3-1.1
Bone: cortical thickness0.80.91.71.2-1.2-1.31.3-1.31.00.91.3-1.3-1.0-0.81.00.60.60.80.80.80.80.50.60.60.50.9-0.70.91.10.1-1.2
Bone: cortical tissue density2.73.75.4-2.32.32.2-2.22.2-2.3-2.2-2.22.22.02.0-2.0-1.8-1.8-2.0-2.0-2.0-2.0-1.7-1.9-1.8-1.8-1.31.4-1.2-1.6-1.41.3
Condit. Reinf. active minus inactive responses2.52.83.71.9-1.9-1.81.9-1.91.81.81.8-1.8-1.8-1.71.81.61.61.71.71.71.81.51.61.61.51.5-0.41.51.81.3-1.5
Condit. Reinf. active-inactive response ratio1.21.31.81.3-1.3-1.21.2-1.21.11.11.2-1.2-1.2-1.11.21.11.11.11.11.11.11.01.01.00.91.2-0.01.21.30.7-1.0
Condit. Reinf. active responses4.45.57.22.7-2.7-2.52.6-2.62.62.62.5-2.5-2.5-2.42.52.22.32.42.42.42.52.22.32.22.22.0-0.91.92.31.9-2.1
Condit. Reinf. inactive responses1.11.31.91.3-1.3-1.21.3-1.31.31.41.2-1.2-1.2-1.21.21.01.11.21.21.11.21.11.21.11.10.9-0.40.91.11.1-1.2
Incentive salience index mean2.12.53.31.8-1.8-1.71.7-1.71.81.71.7-1.7-1.7-1.71.71.61.61.71.71.71.71.51.61.61.51.3-0.61.31.61.4-1.1
Condit. Reinf. lever presses0.20.31.00.3-0.3-0.30.2-0.20.50.40.3-0.3-0.5-0.70.50.80.70.70.70.70.60.80.70.80.80.50.20.50.61.0-0.1
Condit. Reinf. active minus inactive responses0.50.71.00.8-0.8-0.70.8-0.90.91.00.7-0.7-0.9-0.90.90.80.90.90.80.80.90.90.90.90.90.5-0.50.50.50.9-0.8
Condit. Reinf. active-inactive response ratio0.91.12.71.4-1.4-1.41.5-1.51.41.31.4-1.4-1.1-1.01.10.60.80.90.90.90.90.60.80.70.70.3-1.60.10.50.4-0.7
Condit. Reinf. active responses0.30.40.90.2-0.2-0.20.3-0.30.30.70.1-0.1-0.6-0.60.60.70.70.70.50.40.70.80.80.70.60.90.60.80.50.9-0.9
Condit. Reinf. inactive responses0.30.43.2-0.90.90.9-0.90.9-0.9-0.5-0.90.90.30.4-0.30.0-0.1-0.3-0.4-0.4-0.30.1-0.1-0.1-0.20.61.80.60.00.2-0.3
Condit. Reinf. lever presses0.81.13.30.6-0.6-0.50.6-0.60.61.10.5-0.5-1.1-1.11.11.31.21.10.90.91.11.31.21.11.01.81.41.61.01.2-1.2
Condit. Reinf. lever reinforcers received0.60.82.20.3-0.3-0.30.4-0.40.40.90.2-0.2-0.9-0.80.91.11.00.90.70.60.91.11.00.90.81.51.21.51.01.1-1.3
Conditioned reinforcement - actives0.00.00.2-0.10.10.2-0.20.2-0.00.2-0.00.00.0-0.2-0.00.30.20.20.00.00.10.20.20.20.20.10.00.1-0.50.40.4
Conditioned reinforcement - inactives0.40.61.20.5-0.5-0.50.9-0.90.80.71.0-1.0-0.8-1.00.80.80.70.90.40.60.70.50.70.70.60.9-0.80.91.10.3-0.4
Conditioned locomotion0.10.10.40.0-0.0-0.00.2-0.20.30.60.5-0.5-0.3-0.60.30.60.40.60.30.30.30.40.40.40.40.3-0.30.20.10.40.2
Patch foraging indifference point 0 sec0.10.10.30.4-0.4-0.50.4-0.40.30.40.3-0.3-0.5-0.40.50.50.40.30.40.40.40.40.30.30.20.60.30.30.20.2-0.1
Patch foraging indifference point AUC0.10.10.30.2-0.2-0.00.1-0.10.20.40.1-0.1-0.3-0.20.30.40.30.30.20.20.30.30.30.30.30.40.20.50.30.60.1
Delay disc. indifference point, 0s delay0.00.00.1-0.10.1-0.10.1-0.10.10.10.4-0.4-0.2-0.30.20.20.20.30.20.20.20.40.20.20.20.10.00.3-0.10.10.0
Delay disc. indifference point, 16s delay0.50.64.7-1.31.31.2-1.21.2-1.1-0.3-0.90.90.50.3-0.5-0.10.0-0.2-0.4-0.3-0.30.20.00.00.10.32.20.3-0.20.5-0.2
Delay disc. indifference point, 2s delay0.50.51.0-1.01.00.9-0.70.7-0.9-1.0-0.30.30.70.7-0.7-0.8-0.8-0.7-0.9-0.8-0.8-0.7-0.7-0.8-0.8-0.50.3-0.3-0.4-0.80.2
Delay disc. indifference point, 24s delay5.66.27.8-2.82.82.7-2.62.6-2.8-2.8-2.62.62.62.6-2.6-2.6-2.6-2.5-2.7-2.7-2.6-2.4-2.5-2.5-2.4-2.21.4-2.6-2.2-2.01.1
Delay disc. indifference point, 4s delay0.50.51.3-0.80.80.6-0.60.6-0.7-0.5-0.40.40.70.8-0.7-0.8-0.8-0.8-0.7-0.8-0.7-0.4-0.7-0.8-0.8-1.10.4-0.7-1.0-0.50.7
Delay disc. indifference point, 8s delay1.21.42.0-1.31.31.2-1.11.1-1.2-1.3-1.01.01.21.3-1.2-1.4-1.3-1.3-1.2-1.4-1.2-1.1-1.2-1.3-1.3-1.40.5-1.3-0.9-1.00.1
Indifference point function ln k0.30.61.3-1.11.11.0-1.11.1-1.0-0.8-1.11.10.80.7-0.8-0.5-0.6-0.7-0.6-0.6-0.7-0.4-0.6-0.5-0.5-0.41.1-0.4-0.6-0.40.4
Indifference point function log k0.30.61.3-1.11.11.0-1.11.1-1.0-0.8-1.11.10.80.7-0.8-0.5-0.6-0.7-0.6-0.6-0.7-0.4-0.6-0.5-0.5-0.41.1-0.4-0.6-0.40.4
Patch foraging total patch changes 0 sec0.10.30.80.5-0.5-0.50.5-0.50.30.60.4-0.4-0.6-0.50.60.70.60.50.50.50.50.60.50.40.40.90.60.60.40.4-0.3
Patch foraging total patch changes 12 sec0.00.00.40.2-0.2-0.20.3-0.30.10.20.1-0.1-0.10.10.1-0.1-0.1-0.1-0.2-0.2-0.0-0.2-0.1-0.2-0.30.0-0.1-0.3-0.4-0.20.6
Patch foraging total patch changes 18 sec0.30.42.50.0-0.00.10.0-0.0-0.00.60.1-0.1-0.5-0.50.50.90.80.50.50.60.60.80.70.60.61.21.61.10.30.90.1
Patch foraging total patch changes 24 sec0.81.32.61.0-1.0-1.11.2-1.21.11.11.3-1.3-1.3-1.31.31.31.21.21.11.21.21.01.11.11.01.6-0.11.31.10.7-0.9
Patch foraging total patch changes 6 sec0.10.20.90.7-0.7-0.60.8-0.80.60.40.7-0.7-0.4-0.40.40.30.20.30.30.30.30.00.20.10.10.1-0.90.00.10.00.3
Patch foraging time to switch 0 sec0.40.81.2-0.90.90.9-1.01.0-1.0-1.0-0.90.91.00.9-1.0-1.1-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.80.3-0.9-1.0-0.80.4
Patch foraging water rate 0 sec2.24.66.42.1-2.1-2.02.2-2.22.12.42.1-2.1-2.4-2.32.42.52.32.32.12.22.32.22.22.12.02.5-0.02.42.21.8-1.2
Patch foraging water rate 12 sec0.81.62.90.7-0.7-0.80.8-0.80.81.40.7-0.7-1.3-1.31.41.71.51.41.31.31.41.61.51.41.41.71.31.51.31.5-1.2
Patch foraging water rate 18 sec1.52.34.31.2-1.2-1.21.1-1.11.41.71.2-1.2-1.6-1.71.62.11.81.81.61.71.71.81.81.81.81.60.41.51.51.8-0.9
Patch foraging water rate 24 sec4.96.911.62.0-2.0-1.92.1-2.12.12.82.1-2.1-2.8-2.82.83.33.02.82.62.72.83.02.92.82.73.41.53.43.02.6-2.4
Patch foraging water rate 6 sec0.40.61.40.4-0.4-0.40.5-0.50.60.80.5-0.5-0.8-0.90.81.20.90.90.80.90.91.00.90.91.00.70.30.80.51.10.4
Seeking ratio, delayed vs. immediate footshock1.31.62.51.6-1.6-1.41.3-1.31.41.21.5-1.5-1.3-1.21.31.01.21.21.31.21.21.11.11.11.11.1-0.61.51.21.0-1.1
Distance traveled before self-admin0.60.71.61.1-1.1-1.11.3-1.20.90.61.0-1.0-1.0-0.81.00.70.60.70.60.70.70.60.50.50.41.0-0.40.91.20.30.7
Distance traveled after self-admin1.41.83.61.2-1.2-1.21.2-1.21.11.31.0-1.0-1.4-1.31.51.61.51.31.31.41.41.51.31.31.31.80.91.71.91.1-0.4
Extensor digitorum longus weight0.62.34.70.7-0.7-0.70.7-0.70.91.50.6-0.6-1.5-1.51.51.81.81.61.51.51.62.01.81.81.82.21.72.11.52.0-1.8
Bone: elastic displacement0.70.92.11.4-1.4-1.31.3-1.31.11.11.3-1.3-1.0-0.80.90.80.60.70.70.70.80.40.60.50.40.5-0.90.40.50.1-0.7
Bone: elastic work2.93.89.63.1-3.1-3.03.1-3.12.52.23.0-3.0-1.9-1.51.90.91.01.21.41.31.50.50.90.70.50.7-2.70.61.3-0.4-1.3
Bone: endosteal estimation0.20.41.10.1-0.1-0.10.1-0.10.20.40.0-0.0-0.5-0.60.60.70.80.70.60.60.70.90.80.80.81.10.90.90.61.0-0.4
Bone: endosteal perimeter0.40.91.81.3-1.3-1.31.2-1.21.20.81.2-1.2-0.9-1.00.90.50.70.91.00.90.90.60.70.80.80.4-1.20.20.80.4-0.1
Epididymis fat weight1.86.28.02.7-2.7-2.62.4-2.42.52.52.5-2.5-2.7-2.62.72.72.52.62.72.62.62.52.52.52.42.60.12.52.82.2-1.9
Delta time in closed arm before/after self-admin0.20.20.9-0.00.00.1-0.20.20.40.40.0-0.0-0.1-0.50.10.40.50.60.50.50.30.40.60.70.8-0.3-0.9-0.0-0.70.80.3
Delta time in open arm before/after self-admin0.10.10.80.0-0.0-0.00.00.0-0.1-0.10.0-0.0-0.2-0.20.20.30.10.2-0.10.10.10.20.10.10.10.60.90.50.60.00.3
Diff in mean of infusions in LGA sessions0.10.10.80.3-0.3-0.30.4-0.40.1-0.10.3-0.3-0.1-0.00.1-0.0-0.1-0.0-0.1-0.10.0-0.1-0.1-0.1-0.20.4-0.30.30.1-0.20.9
Delay discount exponential model param2.32.53.92.0-2.0-1.81.8-1.81.91.61.6-1.6-1.7-1.71.61.61.51.61.71.71.61.21.41.51.51.4-1.41.41.41.0-0.4
Extinction: sum of active levers before priming0.50.61.0-0.70.70.7-0.80.8-0.9-1.0-0.80.80.80.8-0.8-0.5-0.9-0.8-0.9-0.8-0.8-0.8-0.9-0.8-0.8-0.60.3-0.6-0.3-0.80.8
Active lever presses in extinction session 61.71.74.8-1.01.01.0-0.60.7-1.2-1.7-0.50.51.11.3-1.1-1.2-1.6-1.5-1.6-1.5-1.5-1.7-1.7-1.7-1.9-0.6-0.1-0.9-0.3-2.21.8
Bone: final force4.67.411.63.3-3.3-3.43.4-3.43.23.03.3-3.3-2.9-2.72.92.32.42.62.72.72.72.12.42.32.22.1-1.92.12.61.5-2.0
Bone: final moment5.08.013.33.6-3.6-3.63.6-3.63.43.13.6-3.6-3.1-2.83.02.32.42.62.82.72.82.12.32.22.12.1-2.12.12.61.3-2.0
Food consumed during 24 hour testing period0.50.61.50.9-0.9-0.80.9-0.90.80.70.9-0.9-0.9-0.80.90.90.70.80.70.70.80.70.70.70.60.9-0.10.91.20.5-0.5
Glucose12.018.926.0-3.83.83.8-3.53.5-4.3-4.5-3.83.84.54.8-4.5-4.9-5.0-4.9-4.9-4.9-4.8-5.0-5.0-5.0-5.1-4.00.2-4.2-4.1-5.03.4
Heart weight0.40.61.30.9-0.9-1.01.1-1.10.80.81.1-1.1-0.9-0.60.90.50.50.50.50.50.60.40.40.40.20.8-0.10.50.9-0.0-0.9
Delay discount hyperbolic model param2.12.43.71.9-1.9-1.81.7-1.71.81.61.5-1.5-1.6-1.61.61.61.51.61.61.71.51.21.41.51.51.4-1.31.31.31.1-0.4
Intermittent access intake day 1-15 change0.10.21.20.7-0.7-0.60.7-0.70.41.10.6-0.6-0.30.00.3-0.10.2-0.1-0.10.00.10.0-0.2-0.2-0.30.2-0.50.20.4-0.30.2
Intermittent access intake escalation0.10.21.20.7-0.7-0.60.7-0.70.41.10.5-0.5-0.3-0.00.3-0.10.2-0.1-0.00.10.10.1-0.1-0.1-0.20.2-0.50.20.4-0.20.2
Intermittent access intake escalation 20.50.51.51.1-1.1-1.11.2-1.20.81.21.1-1.1-0.6-0.20.60.00.30.10.20.30.30.0-0.1-0.1-0.20.4-1.20.40.6-0.51.0
Intermitt. access day 1 inactive lever presses1.24.410.12.0-2.0-1.92.1-2.11.92.51.8-1.8-2.3-2.12.32.12.22.11.72.02.22.12.11.91.82.40.32.43.21.6-2.2
Intermitt. access day 15 inactive lever presses1.02.13.41.0-1.0-1.01.2-1.21.31.81.3-1.3-1.6-1.71.61.81.71.71.21.61.51.61.71.61.51.80.11.81.81.2-0.8
Intermitt. access escalation Index0.71.01.50.7-0.7-0.80.8-0.80.91.20.9-0.9-1.0-1.11.01.11.21.11.01.11.11.21.21.11.11.00.11.01.01.0-1.2
Intermittent access day 1 total infusions0.10.10.40.4-0.4-0.30.3-0.30.30.60.1-0.1-0.3-0.30.30.40.40.30.50.30.30.30.30.30.30.2-0.00.20.20.3-0.2
Intermittent access day 15 total infusions0.30.52.00.8-0.8-0.70.8-0.80.71.40.7-0.7-0.7-0.60.70.50.80.60.60.60.60.60.50.50.50.6-0.50.60.60.5-0.3
Intermittent access terminal intake (last 3 days)0.50.61.81.0-1.0-0.91.0-1.00.91.40.9-0.9-0.8-0.70.80.60.80.70.70.70.70.50.60.60.50.7-0.80.60.40.40.1
Intermittent access total infusions0.20.20.90.5-0.5-0.50.6-0.60.50.90.5-0.5-0.5-0.50.50.50.60.40.50.40.50.40.40.40.40.4-0.20.40.40.4-0.5
Intermittent access day 1 locomotion0.10.10.20.1-0.1-0.00.1-0.20.30.40.3-0.3-0.2-0.40.20.30.30.40.30.20.20.20.30.30.30.1-0.40.10.10.3-0.0
Intermittent access day 15 total locomotion0.20.31.20.7-0.7-0.60.8-0.80.81.10.7-0.7-0.6-0.60.60.40.50.50.50.40.50.30.40.30.30.3-1.00.30.50.4-0.2
Intermittent access total locomotion0.20.20.80.4-0.4-0.30.6-0.60.50.90.6-0.6-0.5-0.50.50.40.50.50.30.30.40.30.40.30.30.3-0.70.30.50.40.1
Intermittent access standard deviation0.61.24.3-0.70.70.8-0.60.6-1.0-0.2-0.70.71.01.3-1.0-1.2-1.1-1.3-1.3-1.3-1.2-1.2-1.5-1.4-1.5-0.8-0.1-0.9-0.6-1.52.1
Left kidney weight0.10.31.70.2-0.2-0.10.1-0.10.1-0.30.2-0.20.30.3-0.4-0.6-0.7-0.4-0.4-0.5-0.4-0.7-0.6-0.6-0.6-1.0-1.3-1.1-0.6-0.60.6
Right kidney weight0.10.21.50.1-0.1-0.1-0.00.00.1-0.40.1-0.10.40.3-0.4-0.5-0.6-0.3-0.3-0.4-0.4-0.6-0.5-0.4-0.4-1.0-1.2-0.9-0.5-0.40.6
Cocaine induced anxiety0.30.42.20.4-0.4-0.61.0-1.00.4-0.00.8-0.8-0.20.10.2-0.4-0.3-0.3-0.3-0.3-0.2-0.6-0.6-0.6-0.80.2-1.40.21.5-1.20.1
Post-drug Anxiety1.01.13.5-0.70.70.5-0.10.2-0.8-1.1-0.30.30.81.1-0.8-1.3-1.3-1.3-1.3-1.3-1.2-1.3-1.4-1.5-1.7-0.5-0.3-0.60.6-1.90.8
Baseline Anxiety1.82.03.1-1.51.51.6-1.61.6-1.5-1.6-1.61.61.51.5-1.5-1.3-1.4-1.4-1.4-1.5-1.4-1.2-1.2-1.3-1.2-1.41.0-1.3-1.8-0.91.0
Tail length2.811.016.74.0-4.0-4.04.1-4.14.13.63.9-3.9-3.5-3.53.52.93.03.33.43.43.32.63.03.02.92.1-3.11.92.52.1-1.9
Length with tail0.94.115.02.8-2.8-2.83.0-2.92.81.83.0-3.0-1.9-1.91.91.11.11.71.71.71.60.61.21.11.00.5-3.90.41.10.2-0.0
Length without tail0.30.86.90.4-0.4-0.50.7-0.70.4-0.60.9-0.90.30.3-0.3-0.7-0.9-0.4-0.5-0.5-0.6-1.2-0.9-0.9-1.0-0.9-2.6-1.0-0.6-1.61.2
Times rat made contact with spout0.30.42.30.8-0.8-0.81.0-1.00.70.41.0-1.0-0.3-0.10.3-0.1-0.20.0-0.0-0.00.0-0.5-0.2-0.3-0.4-0.2-1.5-0.20.4-0.90.2
Lifetime Intake0.00.00.40.1-0.1-0.10.2-0.20.10.70.1-0.1-0.1-0.10.10.20.30.10.10.10.10.10.10.10.10.2-0.10.20.20.20.0
Liver weight, left0.91.52.0-1.01.01.0-1.11.1-1.1-1.4-1.11.11.31.3-1.3-1.4-1.4-1.3-1.2-1.3-1.3-1.3-1.4-1.3-1.3-1.3-0.3-1.2-1.1-1.21.0
Liver weight, right2.34.16.52.3-2.3-2.32.3-2.32.51.92.6-2.6-2.1-2.32.11.81.92.22.22.22.01.61.92.02.01.1-2.21.11.61.4-0.7
Locomotor activity0.61.03.7-1.11.11.1-1.11.1-1.1-1.1-0.90.91.00.9-1.0-0.8-0.9-0.9-1.1-1.0-1.0-0.8-0.9-0.8-0.8-0.50.6-0.6-0.8-0.91.9
Locomotor testing distance0.51.02.9-1.41.41.5-1.41.4-1.3-1.2-1.11.10.90.7-0.9-0.5-0.6-0.6-1.0-0.8-0.8-0.4-0.6-0.5-0.5-0.01.4-0.0-0.6-0.51.7
Locomotor testing rearing0.10.21.5-0.80.80.8-0.60.6-0.6-0.2-0.30.30.2-0.0-0.20.40.10.1-0.4-0.1-0.10.30.10.00.00.41.20.3-0.30.10.8
Locomotion in novel chamber0.10.10.3-0.40.40.4-0.40.4-0.1-0.20.2-0.20.0-0.3-0.00.60.20.4-0.00.20.10.30.30.30.40.10.10.00.10.5-0.0
Locomotion in novel chamber post-restriction1.82.95.22.3-2.3-2.32.1-2.12.22.01.9-1.9-1.7-1.51.71.31.41.41.81.71.71.31.41.41.30.6-1.40.61.51.4-2.2
Fecal boli incidents, locomotor time 10.10.20.4-0.50.50.6-0.70.7-0.5-0.4-0.30.30.50.3-0.5-0.2-0.3-0.2-0.3-0.3-0.3-0.1-0.2-0.2-0.1-0.30.2-0.2-0.5-0.10.7
Change in fecal boli incidents, locomotor task3.73.64.8-1.61.61.6-1.41.4-1.8-1.9-1.81.81.92.1-1.9-2.1-2.1-2.2-2.1-2.1-2.0-2.2-2.1-2.2-2.2-1.70.0-2.2-2.2-2.01.6
Time >=10cm from walls, locomotor time 11.11.22.51.0-1.0-1.10.7-0.71.11.40.7-0.7-1.0-1.01.01.21.31.11.51.31.21.41.31.31.40.50.20.30.51.6-1.1
Bouts of movement, locomotor time 11.51.72.4-1.51.51.4-1.51.5-1.6-1.4-1.41.41.41.5-1.4-1.4-1.3-1.5-1.3-1.4-1.4-1.0-1.3-1.3-1.3-1.11.1-0.5-0.6-1.10.4
Total resting periods, locomotor time 12.32.53.5-1.71.71.6-1.71.7-1.8-1.7-1.71.71.71.9-1.7-1.7-1.6-1.8-1.6-1.7-1.7-1.4-1.7-1.7-1.6-1.60.8-0.9-0.9-1.40.6
Rest time, locomotor task time 11.01.32.1-1.01.01.0-0.80.8-1.0-1.4-0.90.91.21.3-1.2-1.5-1.3-1.3-1.3-1.3-1.3-1.4-1.3-1.4-1.4-1.2-0.5-1.0-0.7-1.40.6
Distance moved, locomotor task time 10.50.81.30.7-0.7-1.00.8-0.81.01.00.9-0.9-0.9-1.00.91.01.01.01.11.01.01.01.01.01.00.8-0.10.70.30.9-0.5
Vertical activity count, locomotor time 11.02.43.41.2-1.2-1.51.3-1.31.61.61.5-1.5-1.6-1.81.61.81.81.81.91.81.71.81.71.81.81.60.01.41.21.6-1.0
Time >=10cm from walls, locomotor time 20.10.21.40.1-0.1-0.10.0-0.00.30.1-0.00.00.20.1-0.2-0.2-0.2-0.10.2-0.0-0.1-0.1-0.1-0.00.1-1.0-1.2-0.9-1.10.2-0.1
Bouts of movement, locomotor time 20.50.81.4-1.21.21.1-1.21.2-1.1-0.8-1.21.20.90.9-0.9-0.9-0.7-0.9-0.9-0.9-0.8-0.5-0.7-0.7-0.7-0.81.1-0.3-0.1-0.4-0.5
Total resting periods, locomotor time 20.20.30.8-0.80.80.8-0.90.8-0.7-0.3-0.80.80.50.5-0.5-0.4-0.3-0.4-0.4-0.4-0.4-0.1-0.2-0.2-0.2-0.50.90.10.20.1-0.7
Rest time, locomotor task time 20.10.10.6-0.20.20.2-0.30.3-0.1-0.3-0.30.30.40.4-0.4-0.5-0.4-0.4-0.2-0.4-0.3-0.4-0.3-0.3-0.3-0.8-0.6-0.6-0.3-0.2-0.5
Distance moved, locomotor task time 20.10.10.8-0.10.1-0.10.1-0.10.20.10.2-0.2-0.2-0.30.20.20.20.30.20.20.20.20.20.20.30.2-0.30.3-0.50.10.9
Vertical activity count, locomotor time 20.30.40.80.3-0.3-0.30.3-0.30.40.60.3-0.3-0.6-0.80.60.80.80.80.60.70.70.90.80.80.90.60.40.80.10.80.7
Light reinforcement 11.84.46.61.9-1.9-1.91.6-1.62.02.01.8-1.8-2.1-2.32.12.52.32.32.52.42.32.62.32.42.42.00.21.91.82.5-2.2
Light reinforcement 22.63.95.72.1-2.1-2.21.9-1.92.31.92.1-2.1-2.0-2.22.02.12.02.22.42.32.12.12.02.12.11.4-1.01.11.71.9-1.3
Bone: marrow area0.20.41.20.1-0.1-0.10.0-0.10.20.40.0-0.0-0.5-0.60.60.70.80.70.60.50.60.90.80.80.81.10.90.90.61.0-0.4
Bone: maximum diameter0.91.73.61.8-1.8-1.81.7-1.71.81.21.7-1.7-1.3-1.31.20.80.91.21.41.31.20.81.01.01.00.3-1.90.31.00.7-0.1
Bone: maximum force4.58.112.03.4-3.4-3.53.5-3.53.33.13.4-3.4-3.1-2.93.12.42.62.72.92.82.92.32.62.52.42.2-1.82.22.71.7-2.1
Bone: maximum moment4.78.313.33.6-3.6-3.63.6-3.63.43.23.5-3.5-3.1-2.93.12.32.52.72.82.82.92.22.52.42.22.2-2.02.12.81.5-2.1
Mean time between licks in bursts0.61.52.5-1.61.61.6-1.61.6-1.5-1.3-1.51.51.31.2-1.3-1.1-1.1-1.2-1.2-1.2-1.2-0.9-1.1-1.0-1.0-1.00.9-0.9-1.1-0.60.9
Mean num. licks in bursts0.10.21.20.3-0.3-0.10.4-0.4-0.1-0.00.3-0.30.00.3-0.0-0.4-0.4-0.4-0.6-0.5-0.3-0.5-0.5-0.6-0.70.3-0.20.20.3-1.10.1
Cd content in liver0.40.53.5-0.60.60.6-0.50.5-0.40.2-0.60.6-0.2-0.20.20.70.60.30.20.20.30.80.50.50.51.21.91.30.70.9-0.8
Co content in liver0.00.00.10.2-0.2-0.20.2-0.20.10.00.2-0.2-0.1-0.10.10.0-0.00.10.00.00.0-0.0-0.0-0.0-0.1-0.1-0.20.10.3-0.10.2
Cu content in liver0.30.41.90.9-0.9-0.91.0-1.00.70.50.9-0.9-0.3-0.20.3-0.1-0.10.10.10.00.1-0.3-0.1-0.2-0.3-0.2-1.4-0.10.3-0.70.3
Fe content in liver0.10.21.1-0.60.60.6-0.60.6-0.6-0.4-0.60.60.20.2-0.20.0-0.0-0.1-0.2-0.2-0.20.1-0.1-0.00.00.51.00.50.00.20.3
K content in liver2.82.63.91.4-1.4-1.41.3-1.31.71.61.4-1.4-1.6-1.91.61.91.81.91.91.91.81.81.91.92.01.3-0.41.31.32.0-1.4
Mg content in liver2.02.05.60.8-0.8-0.80.6-0.61.21.30.8-0.8-1.3-1.61.31.81.71.71.71.71.61.91.81.92.01.20.41.10.92.4-1.2
Mn content in liver0.10.10.50.3-0.3-0.30.3-0.30.40.30.3-0.3-0.2-0.30.20.30.20.30.30.30.20.10.30.30.3-0.3-0.7-0.3-0.20.3-0.0
Na content in liver0.20.20.50.1-0.1-0.10.0-0.00.30.20.1-0.1-0.3-0.50.30.60.50.50.60.60.40.60.50.60.70.40.10.30.30.7-0.3
Rb content in liver3.13.64.91.7-1.7-1.71.7-1.71.82.11.7-1.7-2.1-2.12.12.22.12.12.02.02.12.12.12.12.12.00.31.71.82.1-1.6
Se content in liver0.50.61.00.7-0.7-0.70.7-0.70.70.80.7-0.7-0.9-0.80.90.90.90.80.80.80.80.80.80.80.81.00.21.00.90.7-0.7
Sr content in liver1.11.02.2-0.60.60.6-0.50.5-0.8-0.9-0.60.60.91.1-0.9-1.3-1.3-1.1-1.2-1.2-1.1-1.3-1.2-1.3-1.3-1.0-0.4-1.1-0.7-1.50.7
Zn content in liver1.41.52.41.4-1.4-1.41.4-1.41.61.51.4-1.4-1.2-1.31.21.21.21.31.31.31.31.11.21.21.20.4-1.20.70.91.1-0.7
Bone: minimum diameter2.34.18.02.8-2.8-2.82.7-2.72.51.92.6-2.6-2.2-2.02.21.51.51.82.01.81.91.21.51.61.41.5-1.91.22.10.8-1.2
Time in familiar zone, hab. session 10.10.10.4-0.20.20.2-0.10.1-0.4-0.2-0.30.30.20.4-0.2-0.4-0.4-0.4-0.5-0.5-0.3-0.4-0.4-0.5-0.6-0.00.3-0.4-0.5-0.6-0.4
Time in novel zone, hab. session 10.10.10.20.2-0.2-0.20.1-0.10.30.20.2-0.2-0.2-0.30.20.40.40.40.40.40.30.40.30.40.40.2-0.10.30.30.50.4
Total zone transitions, hab. session 10.10.21.9-0.60.60.5-0.50.5-0.6-0.2-0.50.50.10.2-0.10.10.1-0.1-0.2-0.1-0.10.20.00.00.00.61.40.40.00.2-0.0
Total locomotion distance, hab. session 10.60.82.80.5-0.5-0.50.4-0.40.40.70.5-0.5-0.9-0.90.91.11.00.90.80.90.91.11.01.00.91.71.31.41.20.9-0.6
Locomotion velocity, hab. session 10.60.92.70.5-0.5-0.60.5-0.50.40.70.6-0.6-1.0-0.91.01.11.11.00.90.91.01.21.01.01.01.71.31.41.40.9-0.6
Time in familiar zone, hab. session 20.20.21.9-0.50.50.5-0.50.5-0.6-0.3-0.50.50.10.2-0.10.1-0.0-0.1-0.3-0.2-0.10.1-0.1-0.1-0.10.61.40.50.20.1-0.3
Time in novel zone, hab. session 20.10.10.5-0.10.10.2-0.20.20.0-0.1-0.10.10.30.2-0.3-0.2-0.2-0.2-0.1-0.1-0.2-0.2-0.1-0.1-0.1-0.7-0.6-0.6-0.5-0.10.4
Total zone transitions, hab. session 20.60.83.1-0.20.20.2-0.20.20.10.7-0.10.1-0.6-0.80.71.11.20.90.80.80.91.31.11.11.21.31.81.30.91.5-0.7
Total locomotion distance, hab. session 22.02.54.50.8-0.8-0.90.8-0.81.11.50.9-0.9-1.6-1.81.61.92.01.91.81.81.82.12.02.02.11.91.11.91.72.1-1.1
Locomotion velocity, hab. session 22.33.05.01.1-1.1-1.21.1-1.11.41.71.2-1.2-1.8-1.91.82.02.12.01.92.02.02.22.12.22.22.00.92.01.92.1-1.2
Novel to familiar place preference ratio1.11.23.21.6-1.6-1.61.8-1.81.31.21.7-1.7-1.2-0.91.20.60.60.70.70.70.90.30.50.40.30.8-1.30.51.1-0.4-0.7
Novelty place preference1.01.12.91.6-1.6-1.61.7-1.71.31.11.6-1.6-1.1-0.81.10.50.50.60.60.60.80.20.40.40.20.7-1.30.41.0-0.5-0.6
Time in novel zone, NPP test0.91.02.51.5-1.5-1.41.6-1.61.21.11.5-1.5-1.1-0.81.10.60.60.70.70.60.80.30.50.40.30.7-1.10.51.0-0.3-0.6
Total zone transitions, NPP test0.71.03.7-0.30.30.3-0.50.4-0.00.5-0.30.3-0.6-0.80.61.21.21.00.90.90.91.51.21.21.41.31.91.40.91.7-0.8
Total locomotion distance, NPP test1.92.65.70.5-0.5-0.50.4-0.40.81.30.6-0.6-1.4-1.71.42.02.01.81.71.81.72.22.02.12.12.11.72.11.62.4-1.4
Locomotion velocity, NPP test1.72.44.40.7-0.7-0.70.6-0.60.91.30.8-0.8-1.5-1.61.51.91.91.71.61.71.72.11.91.92.02.01.52.01.72.1-1.4
Intraocular pressure0.91.32.11.1-1.1-1.11.2-1.21.11.41.2-1.2-1.3-1.21.30.91.21.21.11.01.31.21.21.11.11.20.41.11.10.9-1.4
Delta distance traveled before/after self-admin0.10.21.6-0.20.20.2-0.40.4-0.20.1-0.20.2-0.1-0.10.10.50.40.20.20.30.20.50.30.30.30.51.30.60.40.1-0.5
Delta ambulatory time before/after self-admin0.30.32.0-0.90.90.8-1.01.0-0.8-0.3-0.70.70.50.4-0.5-0.0-0.1-0.3-0.3-0.2-0.30.2-0.1-0.10.0-0.21.4-0.1-0.5-0.0-0.2
Parametrial fat weight0.71.82.11.3-1.3-1.41.3-1.31.41.31.4-1.4-1.4-1.41.41.31.41.41.51.41.41.31.41.41.41.2-0.51.01.41.4-1.0
Pavlov. Cond. lever latency0.70.98.4-0.80.80.8-0.80.8-0.80.1-0.80.8-0.2-0.20.20.70.70.30.10.10.30.90.60.60.61.62.91.80.81.0-1.1
Pavlov. Cond. magazine entry latency0.70.83.31.5-1.5-1.51.6-1.51.20.91.4-1.4-0.7-0.50.70.10.10.30.40.40.4-0.20.10.0-0.1-0.0-1.8-0.30.3-0.6-0.5
Pavlov. Cond. change in total contacts0.40.41.90.2-0.2-0.20.3-0.3-0.1-0.30.1-0.10.40.6-0.4-0.8-0.9-0.7-0.6-0.7-0.6-1.1-0.9-1.0-1.1-0.6-0.9-1.0-0.5-1.40.2
Pavlov. Cond. index score1.31.66.52.0-2.0-1.91.9-1.91.81.21.8-1.8-1.1-1.01.00.50.50.81.00.90.90.20.50.50.4-0.1-2.5-0.40.5-0.1-0.2
Pavlov. Cond. latency score0.91.27.71.6-1.6-1.61.6-1.61.50.81.6-1.6-0.7-0.60.60.00.10.40.60.60.5-0.20.10.10.1-0.6-2.8-0.90.1-0.50.3
Pavlov. Cond. lever contacts0.40.54.30.9-0.9-0.90.8-0.80.90.30.8-0.8-0.2-0.20.2-0.1-0.10.10.30.30.1-0.3-0.1-0.1-0.0-0.9-2.1-1.0-0.2-0.30.6
Pavlov. Cond. magazine entry number0.70.84.4-1.41.41.3-1.51.5-1.0-0.6-1.31.30.40.1-0.40.40.30.1-0.10.0-0.10.70.40.50.60.42.10.80.11.20.3
Pavlov. Cond. intertrial magazine entries1.01.22.30.7-0.7-0.70.6-0.70.81.10.7-0.7-1.1-1.11.11.31.31.21.11.11.21.31.31.31.31.30.61.31.01.4-1.5
Pavlov. Cond. lever-magazine prob. diff.1.21.55.41.9-1.9-1.91.9-1.91.71.21.8-1.8-1.1-1.01.10.50.50.81.00.90.90.20.50.50.40.0-2.3-0.30.5-0.1-0.2
Pavlov. Cond. response bias0.60.74.81.2-1.2-1.21.3-1.20.90.51.1-1.1-0.3-0.10.3-0.3-0.3-0.10.10.00.0-0.6-0.3-0.4-0.5-0.7-2.2-1.0-0.3-1.00.0
Pavlov. Cond. lever latency2.22.95.8-1.31.31.2-1.31.3-1.3-1.8-1.21.21.81.8-1.8-2.1-2.0-1.9-1.7-1.7-1.8-2.0-1.9-1.9-1.8-2.4-1.0-2.4-1.8-1.81.6
Pavlov. Cond. magazine entry latency0.60.86.0-1.21.21.3-1.21.2-1.2-0.5-1.21.20.50.4-0.40.20.0-0.3-0.5-0.4-0.30.2-0.1-0.0-0.00.82.40.90.10.40.0
Pavlov. Cond. change in total contacts0.40.74.9-0.20.20.2-0.20.2-0.20.4-0.20.2-0.5-0.50.60.90.80.60.40.40.61.00.70.70.61.72.21.81.10.8-0.8
Pavlov. Cond. index score0.50.74.5-0.10.10.1-0.00.0-0.20.5-0.10.1-0.6-0.50.61.00.80.60.40.40.61.00.70.70.61.82.11.81.10.8-0.8
Pavlov. Cond. latency score0.60.84.0-0.00.00.1-0.00.0-0.10.6-0.10.1-0.7-0.60.71.10.90.70.50.60.71.10.90.80.81.82.01.81.10.9-0.8
Pavlov. Cond. lever contacts1.92.65.91.1-1.1-1.01.1-1.11.11.61.1-1.1-1.7-1.71.72.01.91.71.51.61.71.91.81.71.72.31.22.41.81.7-1.5
Pavlov. Cond. magazine entry number0.40.65.50.9-0.9-0.90.9-0.90.90.30.9-0.9-0.2-0.20.2-0.4-0.20.00.20.20.1-0.4-0.1-0.1-0.1-1.0-2.4-1.1-0.4-0.40.2
Pavlov. Cond. intertrial magazine entries1.42.12.91.5-1.5-1.61.6-1.61.71.71.6-1.6-1.6-1.61.61.31.51.51.51.51.51.41.51.41.41.1-0.91.01.21.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.40.65.0-0.30.30.4-0.30.3-0.40.2-0.40.4-0.4-0.30.40.80.60.40.20.20.40.80.50.50.41.62.21.70.90.6-0.6
Pavlov. Cond. response bias0.71.03.70.3-0.3-0.20.3-0.30.20.80.2-0.2-0.9-0.90.91.31.10.90.70.80.91.31.11.01.01.91.81.91.21.1-1.0
Time in closed arm before self-admin0.81.12.2-0.60.60.6-0.70.7-0.9-1.1-0.90.91.11.4-1.1-1.5-1.3-1.4-1.0-1.2-1.1-1.3-1.3-1.3-1.3-1.00.1-1.2-0.7-1.0-0.2
Time in closed arm after self-admin2.02.13.7-1.11.11.2-1.21.2-1.2-1.4-1.21.21.61.7-1.6-1.9-1.6-1.7-1.4-1.6-1.6-1.7-1.6-1.5-1.5-1.9-0.9-1.9-1.6-1.30.5
Time in open arm before self-admin0.50.51.20.2-0.2-0.20.3-0.30.80.60.6-0.6-0.5-1.00.50.90.81.10.80.90.70.81.01.01.10.1-1.10.2-0.51.00.6
Time in open arm after self-admin0.30.30.80.2-0.2-0.20.2-0.20.30.50.2-0.2-0.6-0.70.60.80.70.70.50.70.60.90.70.70.70.90.80.70.50.60.5
Bone: periosteal estimation1.42.94.52.1-2.1-2.12.0-2.02.01.72.0-2.0-1.9-1.81.81.41.61.71.81.71.81.41.61.61.51.4-1.21.21.61.1-1.0
Bone: periosteal perimeter1.32.310.52.4-2.4-2.42.3-2.32.11.32.2-2.2-1.2-1.11.20.30.50.91.11.01.00.10.50.50.4-0.2-3.2-0.30.6-0.30.0
Bone: post-yield work0.00.10.3-0.10.10.1-0.10.10.10.2-0.10.1-0.2-0.20.20.30.30.30.20.20.20.50.40.40.40.30.40.30.10.60.1
Progressive ratio test 1 active lever presses0.30.41.20.7-0.7-0.70.7-0.70.61.10.6-0.6-0.7-0.60.70.60.80.60.60.60.70.70.60.60.60.70.00.70.70.50.1
Progressive ratio test 1 breakpoint0.40.51.40.8-0.8-0.80.8-0.80.71.20.7-0.7-0.8-0.70.80.60.80.60.70.70.70.70.60.70.60.7-0.10.70.70.50.0
Progressive ratio test 1 inactive lever presses3.85.58.42.3-2.3-2.22.3-2.32.32.92.2-2.2-2.5-2.52.52.62.62.52.32.42.52.42.42.42.32.4-0.22.42.62.0-1.3
Progressive ratio test 2 active lever presses0.20.20.80.5-0.5-0.40.5-0.50.50.90.5-0.5-0.5-0.40.50.40.50.40.60.30.50.50.50.40.40.4-0.10.40.40.5-0.5
Progressive ratio test 2 breakpoint0.20.20.90.5-0.5-0.50.5-0.50.51.00.5-0.5-0.5-0.40.50.40.50.40.60.40.50.50.50.40.40.4-0.00.40.40.5-0.5
Progressive ratio test 2 inactive lever presses0.10.20.80.4-0.4-0.40.6-0.60.50.90.6-0.6-0.4-0.40.40.40.40.30.10.20.30.30.20.10.10.5-0.60.50.40.00.4
Incentive Sensitization - Responses0.10.20.50.4-0.4-0.40.4-0.50.40.60.5-0.5-0.4-0.30.40.30.40.30.50.30.40.40.40.30.30.2-0.10.20.30.3-0.7
Incentive Sensitization - Breakpoint0.10.10.40.4-0.4-0.30.4-0.40.40.60.4-0.4-0.3-0.30.30.20.30.30.40.20.30.30.30.20.20.2-0.10.20.20.2-0.6
Sum of active levers in priming session hrs 5-60.40.41.90.4-0.4-0.40.7-0.7-0.10.00.6-0.6-0.50.10.50.2-0.0-0.20.00.00.1-0.1-0.2-0.3-0.51.21.41.01.2-0.90.6
Progressive ratio0.61.01.7-1.21.21.3-1.11.1-1.2-0.9-1.21.21.01.0-1.0-0.7-1.0-1.0-1.1-1.0-1.0-0.9-0.9-1.0-1.0-0.70.7-0.6-0.9-0.70.7
Food seeking constrained by brief footshock0.60.71.5-0.50.50.5-0.50.5-0.8-1.0-0.70.70.81.0-0.8-0.9-1.0-1.0-1.0-1.0-0.9-1.2-1.1-1.1-1.2-0.5-0.1-0.40.1-1.2-0.4
Seeking ratio, punishment vs. effort0.20.31.50.5-0.5-0.60.4-0.40.40.40.5-0.5-0.5-0.40.50.30.50.40.50.40.50.60.50.50.50.70.20.61.00.3-1.2
Retroperitoneal fat weight4.017.121.54.3-4.3-4.44.2-4.24.24.24.2-4.2-4.5-4.44.54.44.24.34.34.24.33.94.14.13.94.3-0.74.14.63.4-3.6
Reaction time number correct2.44.710.00.8-0.8-0.90.6-0.61.12.10.8-0.8-2.0-2.32.03.02.82.52.32.52.33.22.72.82.92.82.52.81.63.0-1.3
Reaction time mean minus median0.20.61.0-0.40.40.5-0.50.5-0.5-0.9-0.30.30.80.8-0.8-1.0-0.9-0.8-0.8-0.8-0.9-1.0-0.9-0.9-0.8-1.0-1.0-0.8-0.7-0.90.7
Reaction time mean minus median AUC0.10.22.0-0.10.10.1-0.10.10.1-0.20.2-0.20.30.1-0.3-0.3-0.2-0.1-0.1-0.0-0.3-0.3-0.2-0.2-0.1-0.8-1.4-0.5-0.6-0.20.4
Reaction time num false alarms0.20.30.6-0.50.50.5-0.60.6-0.7-0.6-0.70.70.50.6-0.5-0.6-0.5-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.10.8-0.1-0.1-0.50.1
Reaction time num false alarms AUC0.30.51.0-0.90.90.8-0.90.9-1.0-0.8-1.01.00.70.8-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.6-0.6-0.6-0.5-0.30.9-0.3-0.3-0.40.2
Reaction time trials correct on left2.44.710.00.8-0.8-0.90.6-0.61.12.10.8-0.8-2.0-2.32.03.02.82.52.32.52.33.22.72.82.92.82.52.81.63.0-1.3
Reaction time trials on left2.64.810.20.8-0.8-0.90.6-0.61.22.10.8-0.8-2.0-2.32.13.02.82.52.32.52.43.22.82.82.92.92.52.81.63.0-1.2
Reaction time mean0.40.61.20.8-0.8-0.70.6-0.60.70.60.8-0.8-0.7-0.80.70.80.80.80.80.80.70.70.70.80.80.80.01.11.00.7-0.7
Reaction time mean AUC0.50.81.60.8-0.8-0.70.5-0.60.70.80.9-0.9-0.8-1.00.81.01.01.01.01.00.91.00.91.01.11.00.21.31.01.1-0.8
Median of all reaction times0.81.12.30.9-0.9-0.80.8-0.80.80.91.0-1.0-1.0-1.11.01.11.11.11.11.11.01.11.01.11.11.30.41.51.31.1-1.0
Reaction time omissions0.30.50.80.6-0.6-0.50.5-0.50.60.40.9-0.9-0.7-0.90.70.70.70.90.60.80.70.70.70.80.80.8-0.10.90.60.60.3
Reaction time false alarm rate1.92.64.6-1.11.11.1-1.11.1-1.4-1.8-1.31.31.71.8-1.7-2.2-2.0-1.9-1.8-1.9-1.8-2.1-1.9-1.9-1.9-1.7-0.4-1.6-1.1-1.90.8
Reaction time premature initiation rate1.41.93.0-1.71.71.7-1.51.5-1.7-1.4-1.61.61.41.5-1.4-1.4-1.3-1.4-1.5-1.6-1.4-1.1-1.3-1.4-1.4-0.41.4-0.5-0.8-1.20.3
Reaction time premature initiations0.40.76.8-1.11.11.0-1.01.0-0.90.0-0.90.90.10.0-0.10.40.40.1-0.1-0.10.10.70.40.30.31.22.61.10.20.5-0.6
Std. dev. reaction times0.10.20.4-0.60.60.6-0.70.7-0.6-0.6-0.50.50.50.4-0.5-0.4-0.4-0.4-0.4-0.4-0.5-0.3-0.4-0.3-0.2-0.20.40.1-0.2-0.20.3
Reaction time trials completed2.64.810.20.8-0.8-0.90.6-0.61.22.10.8-0.8-2.0-2.32.13.02.82.52.32.52.43.22.82.82.92.92.52.81.63.0-1.2
Reaction time trials AUC2.65.010.40.8-0.8-0.90.6-0.71.22.10.9-0.9-2.1-2.42.13.12.92.62.42.62.43.22.82.92.92.92.52.91.63.1-1.3
Run reversals in cocaine runway, females0.40.45.1-0.70.70.5-0.90.9-0.8-0.1-0.90.90.30.4-0.3-0.20.0-0.3-0.1-0.2-0.10.3-0.00.00.10.42.30.40.20.1-0.6
Run reversals in cocaine runway, males0.50.52.71.1-1.1-0.91.2-1.21.00.41.3-1.3-0.6-0.50.60.20.10.30.50.50.40.00.10.10.0-0.1-1.6-0.10.3-0.2-0.1
Latency to leave start box in cocaine runway0.20.20.7-0.60.60.6-0.60.6-0.5-0.1-0.60.60.40.4-0.4-0.2-0.2-0.4-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.50.8-0.3-0.60.1-0.1
Latency to leave start box in cocaine runway, F0.30.31.4-0.30.30.3-0.40.4-0.00.5-0.20.2-0.2-0.40.20.70.60.50.50.50.50.80.70.70.80.41.20.5-0.11.1-0.4
Latency to leave start box in cocaine runway, M0.40.40.7-0.30.30.3-0.30.3-0.5-0.4-0.50.50.60.8-0.6-0.8-0.7-0.8-0.8-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.0-0.7-0.6-0.80.2
Std. dev. time between licks in bursts2.43.37.01.1-1.1-1.00.8-0.81.21.70.9-0.9-1.8-2.01.82.22.32.12.12.02.02.52.32.32.42.11.42.11.52.6-1.5
Total sessions with >9 infusions0.20.20.8-0.60.60.7-0.60.6-0.5-0.0-0.70.70.50.4-0.5-0.3-0.3-0.4-0.5-0.4-0.5-0.4-0.4-0.3-0.3-0.3-0.0-0.3-0.6-0.40.9
Short access day 1 total inactive lever presses0.10.20.50.1-0.1-0.00.1-0.10.30.20.4-0.4-0.4-0.60.40.40.50.70.40.40.50.40.60.70.70.5-0.20.40.30.7-0.1
Short access day 10 total inactive lever presses1.74.17.22.1-2.1-2.12.3-2.32.21.82.0-2.0-2.2-2.22.22.11.92.12.02.02.11.72.11.91.81.8-0.71.72.21.4-2.7
Short access day 1 total infusions1.01.32.3-1.31.31.4-1.51.5-1.4-0.9-1.51.51.21.1-1.2-0.9-0.9-1.1-1.1-1.1-1.1-0.8-1.0-0.9-0.9-0.81.0-0.8-1.1-0.70.5
Short access day 10 total infusions0.60.71.61.1-1.1-1.01.2-1.21.01.31.0-1.0-0.9-0.80.90.80.80.70.90.70.80.60.60.50.50.7-0.80.71.00.3-0.3
Short access total infusions0.00.00.1-0.20.20.2-0.10.1-0.20.3-0.20.20.10.1-0.10.10.1-0.1-0.1-0.1-0.10.0-0.1-0.1-0.10.30.40.20.3-0.10.1
Short access day 1 locomotion0.40.50.8-0.50.50.6-0.60.6-0.6-0.3-0.90.90.70.8-0.7-0.7-0.7-0.8-0.7-0.7-0.8-0.7-0.8-0.8-0.8-0.8-0.1-0.8-0.9-0.70.7
Short access day 10 total locomotion0.50.92.5-0.50.50.5-0.30.3-0.5-0.6-0.40.40.80.8-0.8-1.0-1.0-0.9-1.0-1.0-1.0-1.2-1.1-1.1-1.1-1.1-1.2-1.1-1.1-1.31.6
Short access total locomotion0.40.41.4-0.30.30.3-0.10.1-0.30.0-0.40.40.60.6-0.6-0.7-0.6-0.6-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.8-1.1-0.9-0.8-0.91.2
One hour access (0.3 mA shock)0.40.41.60.7-0.7-0.60.5-0.50.61.30.5-0.5-0.7-0.60.70.70.80.60.80.60.70.70.60.70.70.60.30.60.60.8-0.5
Compulsive drug intake1.51.72.91.1-1.1-1.10.9-1.01.11.20.9-0.9-1.4-1.41.41.51.51.41.41.51.41.41.51.51.51.60.51.61.71.6-1.0
One hour access (shock baseline)0.00.10.40.1-0.1-0.10.1-0.10.20.50.2-0.2-0.1-0.10.00.00.10.10.20.00.10.20.10.10.2-0.3-0.6-0.3-0.60.1-0.2
Social response proportion0.10.10.6-0.80.80.5-0.50.5-0.4-0.2-0.20.20.20.0-0.20.10.00.0-0.2-0.1-0.10.10.00.00.10.30.5-0.0-0.5-0.10.6
Social responses0.00.00.1-0.20.20.1-0.30.3-0.0-0.2-0.10.10.0-0.2-0.00.30.10.20.10.20.10.20.10.20.30.10.2-0.2-0.20.30.4
Social time0.00.00.3-0.10.10.1-0.20.2-0.10.1-0.10.1-0.0-0.10.00.20.10.10.10.10.10.20.10.20.20.20.5-0.4-0.50.10.2
Soleus weight1.13.35.32.1-2.1-2.22.1-2.22.32.02.2-2.2-1.9-1.91.81.51.71.81.91.91.81.51.71.61.60.9-1.71.21.71.2-1.2
Bone: stiffness0.61.01.51.0-1.0-1.11.1-1.11.21.01.0-1.0-1.1-1.11.10.81.01.11.21.11.11.01.11.11.10.8-0.51.01.20.9-0.7
Tibialis anterior weight0.10.20.60.1-0.1-0.20.2-0.20.40.50.1-0.1-0.4-0.50.40.40.60.50.50.50.50.70.60.60.70.30.20.30.20.8-0.6
Time to tail flick, vehicle, before self-admin0.30.31.2-0.50.50.6-0.60.6-0.4-0.6-0.50.50.60.5-0.6-0.5-0.6-0.5-0.3-0.5-0.5-0.5-0.4-0.4-0.4-0.9-0.3-1.1-0.9-0.2-0.1
Time to tail flick, vehicle, after self-admin1.51.92.8-1.71.71.6-1.71.6-1.4-1.5-1.61.61.61.2-1.6-1.4-1.3-1.1-1.3-1.3-1.4-1.3-1.1-1.1-0.9-1.5-0.3-1.4-1.6-0.81.4
Time to tail flick, test, before self-admin0.50.50.8-0.90.90.8-0.50.5-0.6-0.6-0.50.50.70.8-0.7-0.9-0.8-0.8-0.9-0.8-0.8-0.9-0.7-0.8-0.8-0.8-0.3-0.7-0.3-0.8-0.6
Time to tail flick, test, after self-admin1.81.92.8-1.41.41.4-1.11.1-1.2-1.7-1.01.01.51.3-1.5-1.3-1.5-1.3-1.5-1.4-1.5-1.7-1.4-1.4-1.4-1.6-0.8-1.6-1.4-1.61.2
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.10.10.1-0.0-0.00.10.30.1-0.1-0.3-0.50.30.40.50.50.20.30.30.50.50.50.50.40.10.60.30.40.5
Delta time to tail flick, test, before/after SA0.80.81.9-0.70.70.7-0.70.7-0.8-1.1-0.70.70.90.9-0.9-0.9-1.0-0.9-0.8-0.9-1.0-1.1-1.0-1.0-1.0-1.0-0.3-1.1-1.2-1.01.4
Tibia length5.214.328.75.3-5.3-5.35.3-5.34.94.35.4-5.4-3.8-3.53.82.32.73.13.53.43.32.02.62.52.31.3-4.81.62.80.9-1.7
Ambulatory time before self-admin1.52.24.01.9-1.9-1.82.0-2.01.61.31.6-1.6-1.7-1.51.71.41.31.41.31.41.41.21.11.11.01.7-0.51.52.00.80.1
Ambulatory time after self-admin1.01.12.21.0-1.0-1.00.9-0.90.91.00.8-0.8-1.2-1.11.21.31.21.11.01.21.11.31.01.01.01.40.81.31.50.8-0.0
Bone: tissue strength2.82.83.41.8-1.8-1.81.7-1.71.81.81.8-1.8-1.8-1.81.81.81.71.71.81.81.81.61.71.71.71.4-0.61.51.61.5-1.1
Total heroin consumption0.20.21.3-0.10.1-0.00.2-0.1-0.2-0.80.2-0.20.10.1-0.1-0.1-0.5-0.2-0.5-0.3-0.3-0.4-0.5-0.5-0.60.6-0.20.50.9-1.01.1
Bone: trabecular number0.00.00.20.1-0.1-0.10.0-0.10.1-0.10.1-0.10.10.0-0.1-0.2-0.1-0.0-0.00.0-0.1-0.1-0.0-0.0-0.0-0.4-0.5-0.3-0.20.00.3
Bone: trabecular spacing2.43.16.90.8-0.8-0.80.7-0.71.01.50.8-0.8-1.7-1.81.72.42.11.91.81.91.92.32.12.12.12.61.92.31.82.3-1.8
Bone: trabecular thickness0.40.62.80.5-0.5-0.50.7-0.60.2-0.10.5-0.50.20.5-0.2-1.0-0.8-0.6-0.5-0.6-0.5-1.0-0.8-0.9-1.0-0.9-1.7-1.0-0.5-1.40.4
Bone: trabecular tissue density0.60.91.5-1.21.21.2-1.21.2-1.1-1.1-1.21.21.00.9-1.0-0.8-0.8-0.9-0.9-0.9-0.9-0.7-0.8-0.7-0.6-0.70.6-0.4-0.7-0.30.8
Water consumed over 24 hours0.50.71.5-0.40.40.3-0.30.3-0.4-0.8-0.20.20.80.8-0.8-0.9-1.0-0.9-0.8-0.9-0.9-1.2-1.0-1.0-1.0-1.2-1.2-1.2-0.8-1.21.0
Number of responses in last shaping day0.10.10.7-0.20.20.2-0.00.00.10.40.1-0.10.0-0.2-0.00.20.20.2-0.10.1-0.00.10.10.10.1-0.0-0.70.0-0.2-0.10.8