Hub : Genes

Nod2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA NM_001414911.1 0.15 0.1 5.4e-05 0.02 0.06 0.05 0.04 2.6e-02 5.6e-04 1.7e-03 3.6e-03
2 BLA alternative polyA XM_008772373.3 0.15 0.1 4.9e-05 0.02 0.06 0.05 0.04 2.7e-02 4.9e-04 1.2e-03 2.8e-03
3 BLA gene expression Nod2 0.28 0.13 3.4e-11 0.16 0.19 0.19 0.19 4.5e-09 1.4e-10 3.3e-10 1.3e-10
4 pVTA alternative polyA NM_001414911.1 0.09 0.06 1.9e-03 0.04 0.04 0.04 0.02 6.0e-03 1.0e-02 1.0e-02 3.3e-02
5 pVTA alternative polyA XM_008772373.3 0.09 0.06 1.8e-03 0.04 0.04 0.04 0.02 6.7e-03 1.2e-02 1.1e-02 3.7e-02
6 Adipose gene expression Nod2 0.05 0.04 1.1e-03 0.02 0.01 0.01 0.02 9.1e-04 5.1e-02 7.1e-03 1.5e-03
7 PL alternative polyA XM_008772373.3 0.05 0.04 8.9e-06 0.04 0.04 0.04 0.04 5.3e-05 1.8e-05 2.3e-05 7.5e-05
8 PL alternative polyA NM_001414911.1 0.05 0.04 9.6e-06 0.04 0.04 0.04 0.04 6.5e-05 2.2e-05 2.8e-05 9.1e-05
9 Eye mRNA stability Nod2 0.25 0.17 4.5e-03 0.17 0.16 0.17 0.22 1.3e-03 2.1e-03 1.2e-03 3.0e-04
10 PL gene expression Nod2 0.14 0.08 1.4e-12 0.09 0.1 0.1 0.1 2.7e-10 3.7e-11 5.0e-11 4.1e-11
11 Brain gene expression Nod2 0.19 0.08 0.0e+00 0.24 0.25 0.26 0.25 1.4e-22 2.0e-23 6.3e-24 1.6e-23
12 Brain alternative polyA NM_001414911.1 0.08 0.04 3.1e-10 0.12 0.11 0.11 0.11 3.0e-11 1.5e-10 2.0e-10 1.5e-10
13 Brain alternative polyA XM_008772373.3 0.08 0.04 1.1e-10 0.12 0.12 0.12 0.12 1.1e-11 4.1e-11 6.7e-11 4.6e-11
14 LHb gene expression Nod2 0.32 0.14 9.2e-07 0.22 0.16 0.18 0.08 6.3e-06 1.6e-04 4.0e-05 6.2e-03
15 IL gene expression Nod2 0.16 0.1 6.0e-04 0.13 0.14 0.11 0.12 6.1e-04 2.8e-04 1.3e-03 1.0e-03
16 Brain alternative polyA XM_008772373.3 0.1 0.05 1.4e-13 0.15 0.15 0.15 0.15 7.1e-14 5.2e-14 1.7e-13 7.1e-14
17 Brain alternative polyA NM_001414911.1 0.1 0.05 1.4e-13 0.15 0.15 0.15 0.15 7.9e-14 5.5e-14 1.5e-13 6.3e-14
18 PL alternative polyA NM_001414911.1 0.03 0.02 2.5e-03 0.02 0.01 0.01 0.01 6.1e-03 7.4e-03 1.3e-02 2.6e-02
19 PL alternative polyA XM_008772373.3 0.03 0.02 2.1e-03 0.02 0.02 0.01 0.01 5.0e-03 5.9e-03 7.6e-03 1.7e-02
20 LHb alternative polyA XM_008772373.3 0.18 0.12 5.1e-03 0.07 0.04 0.06 0.06 1.2e-02 4.6e-02 1.6e-02 1.7e-02
21 LHb alternative polyA NM_001414911.1 0.34 0.15 6.9e-05 0.07 0.1 0.06 0.06 8.5e-03 2.9e-03 1.6e-02 1.4e-02
22 LHb alternative polyA XM_008772373.3 0.35 0.16 5.1e-05 0.08 0.1 0.06 0.07 7.0e-03 2.7e-03 1.9e-02 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.83.16.0-2.32.3-1.72.5-2.52.51.9-1.91.9-1.91.61.6-1.61.6-1.61.5-1.51.2-1.2-1.2-0.10.1
Area under the delay curve0.40.40.60.7-0.70.5-0.80.8-0.8-0.70.7-0.80.6-0.6-0.60.6-0.60.6-0.60.6-0.60.60.30.1-0.1
BMI with tail1.75.57.22.6-2.52.5-2.72.7-2.7-2.52.5-2.62.3-2.3-2.62.6-2.62.4-2.32.3-2.42.40.50.8-0.8
BMI without tail0.10.21.0-0.10.2-0.2-0.50.5-0.5-0.00.0-0.8-0.10.3-0.10.1-0.10.10.1-0.1-0.60.6-1.0-0.50.5
Body weight0.62.65.41.8-1.71.4-2.32.3-2.3-1.71.7-2.21.5-1.3-1.61.6-1.71.5-1.31.3-1.61.6-0.3-0.30.3
Weight adjusted by age3.23.65.91.8-1.82.0-2.12.1-2.2-1.91.9-2.11.6-1.9-2.42.4-2.42.0-1.91.9-2.12.10.00.5-0.5
Bone surface0.71.22.6-1.61.6-1.41.3-1.31.31.2-1.20.8-1.31.20.9-0.91.0-1.01.0-1.00.4-0.4-1.3-0.30.3
Bone volume2.13.56.1-2.52.5-2.22.0-2.02.02.1-2.11.6-2.22.01.7-1.71.7-1.81.9-1.91.3-1.3-1.9-1.01.0
Breakpoint value in progressive ratio session0.30.40.6-0.50.5-0.50.8-0.80.80.6-0.60.8-0.40.40.7-0.70.7-0.70.6-0.60.6-0.60.40.0-0.0
Number of licking bursts0.30.30.6-0.40.4-0.60.6-0.60.60.6-0.60.8-0.40.40.7-0.70.8-0.70.6-0.60.8-0.80.3-0.20.2
Context. condit. distance diff. score5.76.910.73.2-3.33.2-1.91.9-1.9-2.92.9-1.63.2-3.0-2.12.1-2.12.7-2.92.9-2.12.13.02.8-2.8
Locomotion velocity, session 10.40.51.2-0.50.5-1.00.0-0.00.00.6-0.6-0.2-0.51.11.1-1.11.1-0.70.8-0.80.3-0.3-0.4-0.90.9
Locomotion distance, session 10.10.21.10.5-0.50.50.0-0.00.0-0.30.3-0.10.5-0.40.2-0.20.20.2-0.30.3-0.10.11.10.6-0.6
Locomotion velocity, session 20.10.10.30.1-0.1-0.00.0-0.00.0-0.10.1-0.00.30.20.4-0.40.40.1-0.10.1-0.20.20.40.5-0.5
Locomotion distance, session 20.30.51.30.8-0.90.9-0.20.2-0.2-0.70.7-0.50.8-0.8-0.40.4-0.40.6-0.70.7-0.50.51.10.9-0.9
Locomotion velocity, session 32.02.33.81.6-1.61.4-1.91.9-1.9-1.61.6-1.81.4-1.3-1.71.7-1.71.6-1.41.4-1.61.60.10.3-0.3
Locomotion distance, session 30.60.61.21.1-1.00.8-1.11.1-1.1-0.90.9-1.10.8-0.8-0.70.7-0.70.7-0.60.6-0.60.60.4-0.10.1
Stereotopy head waving bouts, day 30.91.11.71.1-1.00.9-1.21.2-1.2-1.11.1-1.31.1-0.8-1.01.0-1.01.1-1.01.0-1.31.30.30.5-0.5
Stereotopy head waving duration, day 31.41.72.61.4-1.31.3-1.41.4-1.4-1.41.4-1.51.4-1.1-1.21.2-1.21.4-1.41.4-1.61.60.60.9-0.9
Locomotion velocity, session 72.02.24.51.6-1.61.8-0.50.5-0.5-1.51.5-0.61.7-1.8-1.21.2-1.21.5-1.71.7-1.11.11.92.1-2.1
Locomotion distance, session 70.50.72.70.1-0.20.61.1-1.11.1-0.00.01.20.3-0.60.3-0.30.30.0-0.30.30.5-0.51.61.6-1.6
Stereotopy head waving bouts, day 71.01.23.31.1-1.00.6-1.61.6-1.6-1.01.0-1.80.9-0.6-1.01.0-1.00.9-0.70.7-1.21.2-0.3-0.40.4
Stereotopy head waving duration, day 70.40.52.5-0.10.2-0.7-0.80.8-0.80.1-0.2-1.2-0.30.60.1-0.10.1-0.30.5-0.5-0.30.3-1.1-1.61.6
Locomotion velocity, session 82.22.66.11.8-1.92.0-0.60.6-0.6-1.61.7-0.72.0-1.9-1.01.0-1.01.5-1.81.8-1.21.22.52.5-2.5
Locomotion distance, session 83.04.410.12.6-2.72.6-1.11.1-1.1-2.22.3-1.02.7-2.5-1.41.4-1.42.0-2.22.2-1.41.43.22.7-2.7
Degree of sensitization distance0.60.62.3-0.40.40.21.3-1.31.30.3-0.31.4-0.1-0.10.4-0.40.4-0.2-0.10.10.4-0.40.91.5-1.5
Degree of sensitization stereotypy1.01.13.70.9-0.80.4-1.61.6-1.6-0.90.9-1.90.7-0.4-1.01.0-1.00.8-0.60.6-1.21.2-0.6-0.80.8
Conditioned locomotion0.20.20.4-0.60.6-0.40.5-0.50.50.5-0.50.6-0.60.40.3-0.30.3-0.50.5-0.50.5-0.5-0.4-0.40.4
Cocaine response after cond. corrected1.61.83.31.5-1.51.8-0.90.9-0.9-1.41.4-0.71.5-1.6-1.11.1-1.21.4-1.61.5-1.11.11.41.6-1.6
Cocaine response after cond. not corrected1.11.21.81.2-1.21.4-0.90.9-1.0-1.21.2-0.81.2-1.3-1.01.0-1.11.1-1.21.2-1.01.00.90.9-0.9
Cocaine response before conditioning1.61.94.1-1.41.4-1.80.5-0.50.51.4-1.40.4-1.51.61.2-1.21.2-1.51.6-1.61.1-1.1-1.5-2.02.0
Saline control response1.21.64.7-0.90.8-0.52.2-2.22.21.0-1.01.7-0.50.51.4-1.41.3-1.00.7-0.70.9-0.91.41.3-1.3
Bone: connectivity density1.72.67.2-2.01.9-1.12.7-2.72.71.7-1.62.2-1.51.11.3-1.31.3-1.31.1-1.11.1-1.1-0.40.8-0.8
Bone: cortical apparent density0.30.41.40.5-0.51.00.2-0.20.2-0.50.50.10.6-0.7-0.30.3-0.40.5-0.70.7-0.40.40.91.2-1.2
Bone: cortical area0.10.10.2-0.40.4-0.50.2-0.20.20.4-0.40.1-0.40.50.5-0.50.5-0.40.4-0.40.2-0.2-0.4-0.40.4
Bone: cortical porosity0.10.10.20.4-0.40.2-0.40.4-0.4-0.20.2-0.50.2-0.3-0.50.5-0.50.1-0.00.0-0.00.00.2-0.40.4
Bone: cortical porosity0.10.10.80.2-0.2-0.1-0.50.5-0.50.0-0.0-0.6-0.0-0.0-0.30.3-0.3-0.20.3-0.30.1-0.1-0.1-0.90.9
Bone: cortical thickness0.00.00.2-0.20.20.00.0-0.00.00.2-0.2-0.1-0.20.20.1-0.10.1-0.10.2-0.2-0.00.0-0.4-0.30.3
Bone: cortical thickness0.30.31.10.3-0.30.50.2-0.20.2-0.40.4-0.20.5-0.7-0.50.5-0.50.5-0.60.6-0.80.80.51.0-1.0
Bone: cortical tissue density0.30.51.70.6-0.61.10.2-0.20.2-0.50.50.10.6-0.7-0.40.4-0.40.6-0.70.7-0.40.41.01.3-1.3
Condit. Reinf. active minus inactive responses1.11.32.21.5-1.51.5-0.90.9-0.9-1.21.2-1.11.4-1.3-0.80.8-0.81.1-1.11.1-1.01.01.31.0-1.0
Condit. Reinf. active-inactive response ratio2.02.23.71.9-1.91.7-1.31.3-1.3-1.71.7-1.21.9-1.7-1.11.1-1.11.4-1.51.5-1.31.31.71.2-1.3
Condit. Reinf. active responses0.00.00.20.0-0.00.00.0-0.00.00.1-0.1-0.4-0.00.10.2-0.20.2-0.10.1-0.1-0.20.20.0-0.20.2
Condit. Reinf. inactive responses4.04.86.8-2.62.6-2.52.0-2.02.02.4-2.41.6-2.52.52.1-2.12.1-2.32.3-2.31.8-1.8-1.9-1.81.8
Incentive salience index mean0.10.10.4-0.0-0.0-0.10.3-0.30.30.2-0.20.1-0.00.10.6-0.60.6-0.40.3-0.30.3-0.30.6-0.0-0.0
Condit. Reinf. lever presses1.41.92.7-1.41.4-1.61.2-1.21.21.5-1.41.3-1.31.51.7-1.71.7-1.51.5-1.51.5-1.5-0.4-0.90.9
Condit. Reinf. active minus inactive responses0.00.10.10.3-0.30.3-0.30.3-0.3-0.20.2-0.30.2-0.2-0.10.1-0.10.2-0.20.2-0.10.1-0.1-0.20.2
Condit. Reinf. active-inactive response ratio0.40.42.5-0.50.6-0.5-0.40.4-0.40.3-0.4-0.4-0.70.50.0-0.0-0.0-0.20.4-0.4-0.10.1-1.6-1.31.3
Condit. Reinf. active responses0.10.10.30.5-0.50.2-0.40.4-0.4-0.40.4-0.60.4-0.10.1-0.10.10.3-0.20.2-0.40.40.20.0-0.0
Condit. Reinf. inactive responses0.81.01.91.3-1.31.0-0.70.7-0.7-1.11.1-0.81.4-1.0-0.60.6-0.51.0-1.11.1-0.80.81.41.2-1.2
Condit. Reinf. lever presses0.50.71.01.0-1.00.8-1.01.0-1.0-1.01.0-1.01.0-0.8-0.70.7-0.70.9-0.90.9-0.90.90.40.5-0.5
Condit. Reinf. lever reinforcers received0.20.30.90.7-0.70.4-0.80.8-0.8-0.60.6-0.90.6-0.3-0.20.2-0.20.6-0.50.5-0.60.60.0-0.10.1
Conditioned reinforcement - actives1.21.21.81.3-1.41.2-1.11.1-1.1-1.21.2-0.91.3-1.1-1.01.0-1.01.1-1.21.2-0.90.90.70.9-0.9
Conditioned reinforcement - inactives2.73.05.92.4-2.41.9-1.41.4-1.4-2.02.0-1.72.4-1.8-1.01.0-1.01.6-1.81.8-1.61.61.71.6-1.7
Conditioned locomotion0.10.10.50.3-0.30.4-0.20.2-0.2-0.30.4-0.20.4-0.4-0.20.2-0.20.4-0.40.4-0.40.40.50.7-0.7
Patch foraging indifference point 0 sec1.32.13.41.8-1.81.5-1.21.2-1.3-1.61.6-1.31.8-1.5-1.11.1-1.11.4-1.51.5-1.51.51.71.4-1.4
Patch foraging indifference point AUC1.71.92.9-1.41.4-1.21.7-1.71.71.5-1.51.6-1.41.21.5-1.51.5-1.51.4-1.41.6-1.6-0.2-0.60.6
Delay disc. indifference point, 0s delay1.11.21.9-0.90.9-1.10.8-0.80.81.1-1.10.6-1.01.21.4-1.41.4-1.21.3-1.31.2-1.2-0.3-1.11.1
Delay disc. indifference point, 16s delay0.70.71.00.8-0.80.7-1.01.0-1.0-0.90.9-0.90.7-0.8-1.01.0-1.00.9-0.80.8-0.80.80.10.2-0.2
Delay disc. indifference point, 2s delay0.40.51.30.3-0.30.3-1.01.0-1.0-0.50.5-1.20.3-0.2-0.80.8-0.80.7-0.50.5-0.90.9-0.6-0.30.3
Delay disc. indifference point, 24s delay0.00.00.10.2-0.20.0-0.30.3-0.3-0.20.2-0.20.1-0.1-0.10.1-0.10.1-0.10.1-0.00.0-0.1-0.20.2
Delay disc. indifference point, 4s delay0.30.31.80.4-0.50.60.1-0.10.1-0.40.40.10.5-0.6-0.10.1-0.10.4-0.50.5-0.10.11.30.9-0.9
Delay disc. indifference point, 8s delay1.31.32.21.5-1.41.1-1.51.5-1.5-1.31.3-1.41.3-1.1-1.01.0-1.01.1-1.11.1-1.01.00.60.3-0.3
Indifference point function ln k1.82.54.11.6-1.61.6-1.61.6-1.6-1.71.7-1.81.6-1.6-1.51.5-1.61.7-1.71.7-2.02.00.51.1-1.1
Indifference point function log k1.82.54.11.6-1.61.6-1.61.6-1.6-1.71.7-1.81.6-1.6-1.51.5-1.61.7-1.71.7-2.02.00.51.1-1.1
Patch foraging total patch changes 0 sec1.62.64.01.9-1.91.6-1.41.4-1.5-1.81.8-1.52.0-1.7-1.31.3-1.31.6-1.71.7-1.71.71.71.5-1.5
Patch foraging total patch changes 12 sec0.50.73.00.0-0.10.11.2-1.21.20.3-0.30.80.10.11.1-1.11.1-0.50.3-0.30.6-0.61.70.9-0.9
Patch foraging total patch changes 18 sec1.52.04.5-1.21.1-0.92.1-2.12.11.3-1.31.9-1.01.01.7-1.71.7-1.31.1-1.11.4-1.40.90.4-0.4
Patch foraging total patch changes 24 sec0.30.42.50.2-0.2-0.10.7-0.70.70.1-0.10.70.20.00.9-0.90.9-0.40.2-0.20.7-0.71.60.6-0.6
Patch foraging total patch changes 6 sec0.00.10.60.1-0.1-0.00.4-0.40.30.1-0.00.20.1-0.00.2-0.20.3-0.20.1-0.10.2-0.20.80.3-0.3
Patch foraging time to switch 0 sec0.00.10.50.5-0.50.3-0.20.2-0.2-0.30.3-0.00.4-0.4-0.00.00.00.1-0.10.10.1-0.10.70.1-0.1
Patch foraging water rate 0 sec0.20.30.6-0.80.8-0.60.4-0.40.40.7-0.70.2-0.80.70.5-0.50.4-0.50.6-0.60.3-0.3-0.7-0.60.6
Patch foraging water rate 12 sec0.50.81.5-1.21.2-1.10.7-0.70.71.0-1.00.8-1.11.20.8-0.80.8-0.90.9-0.90.7-0.7-0.9-0.60.6
Patch foraging water rate 18 sec3.34.47.2-2.52.5-2.70.9-0.90.92.2-2.20.9-2.52.71.9-1.91.9-2.12.3-2.31.5-1.5-2.6-2.62.6
Patch foraging water rate 24 sec0.10.20.6-0.60.6-0.40.3-0.30.30.5-0.50.2-0.60.50.4-0.40.3-0.40.4-0.40.1-0.1-0.8-0.40.4
Patch foraging water rate 6 sec3.34.87.0-2.62.6-2.42.4-2.42.42.4-2.42.3-2.32.42.3-2.32.3-2.22.1-2.12.1-2.1-1.1-0.80.8
Seeking ratio, delayed vs. immediate footshock4.85.56.72.6-2.62.4-2.32.3-2.4-2.62.6-2.32.6-2.4-2.42.4-2.32.5-2.52.5-2.52.51.01.7-1.7
Distance traveled before self-admin0.80.92.10.7-0.60.4-1.41.4-1.4-0.80.8-1.40.5-0.4-1.01.0-1.00.8-0.60.6-1.01.0-1.0-0.60.7
Distance traveled after self-admin0.91.04.8-1.11.1-1.1-0.00.0-0.00.8-0.90.0-1.21.10.3-0.30.3-0.70.9-0.90.4-0.4-2.2-1.71.7
Extensor digitorum longus weight0.31.25.0-1.31.3-1.00.2-0.20.21.1-1.10.4-1.51.30.5-0.50.5-0.91.1-1.10.7-0.7-2.2-1.81.8
Bone: elastic displacement0.10.10.50.3-0.30.60.3-0.30.3-0.20.20.40.2-0.5-0.50.5-0.40.2-0.30.30.2-0.20.70.5-0.5
Bone: elastic work0.00.00.0-0.10.10.00.1-0.10.10.1-0.10.1-0.2-0.0-0.20.2-0.2-0.10.1-0.10.1-0.1-0.1-0.20.2
Bone: endosteal estimation0.10.20.30.5-0.50.3-0.50.5-0.5-0.50.5-0.20.5-0.4-0.30.3-0.30.5-0.40.5-0.40.40.30.4-0.4
Bone: endosteal perimeter0.40.81.41.0-1.00.7-0.70.7-0.7-1.01.0-0.41.2-0.9-0.50.5-0.50.9-1.01.0-0.80.81.11.2-1.2
Epididymis fat weight0.10.30.50.7-0.70.6-0.40.4-0.4-0.60.6-0.40.7-0.6-0.40.4-0.40.5-0.60.6-0.40.40.70.6-0.6
Delta time in closed arm before/after self-admin1.11.11.71.0-1.00.9-1.21.2-1.2-1.11.1-1.31.0-0.9-1.21.2-1.11.2-1.11.1-1.31.3-0.10.4-0.4
Delta time in open arm before/after self-admin2.12.13.7-1.41.3-1.21.8-1.81.81.4-1.41.9-1.21.21.6-1.61.6-1.41.3-1.31.7-1.70.3-0.20.1
Diff in mean of infusions in LGA sessions0.40.42.30.5-0.60.70.4-0.40.4-0.40.40.40.6-0.7-0.10.1-0.10.3-0.50.5-0.00.01.51.4-1.4
Delay discount exponential model param0.40.40.6-0.70.7-0.60.7-0.70.70.7-0.70.8-0.70.60.6-0.60.6-0.70.6-0.60.6-0.6-0.5-0.30.3
Extinction: sum of active levers before priming3.13.13.71.9-1.81.9-1.81.8-1.8-1.91.9-1.61.8-1.9-1.91.9-1.91.9-1.91.9-1.71.70.81.3-1.3
Active lever presses in extinction session 60.10.10.2-0.50.5-0.30.4-0.40.40.3-0.30.2-0.40.30.2-0.20.2-0.20.2-0.2-0.10.1-0.4-0.10.1
Bone: final force1.72.74.6-1.81.8-2.10.9-0.90.91.8-1.80.6-1.91.91.6-1.61.5-1.81.9-1.91.1-1.1-1.8-2.12.1
Bone: final moment1.11.73.6-1.41.4-1.70.5-0.50.51.4-1.40.3-1.51.51.2-1.21.2-1.41.6-1.60.8-0.8-1.6-1.91.9
Food consumed during 24 hour testing period5.56.69.4-2.72.6-2.73.1-3.13.12.7-2.72.8-2.42.63.0-3.03.0-2.82.6-2.62.6-2.6-0.2-0.80.8
Glucose0.10.20.5-0.50.5-0.70.3-0.30.30.5-0.50.1-0.50.40.2-0.20.1-0.50.5-0.50.3-0.3-0.4-0.50.5
Heart weight2.23.04.71.7-1.71.5-2.22.2-2.2-1.91.8-2.11.7-1.5-1.91.9-1.91.9-1.71.7-2.02.00.20.6-0.6
Delay discount hyperbolic model param0.40.40.7-0.70.7-0.60.8-0.80.80.7-0.70.8-0.70.60.6-0.60.6-0.70.6-0.60.7-0.7-0.5-0.30.3
Intermittent access intake day 1-15 change2.82.84.5-1.51.4-1.61.8-1.81.81.7-1.71.8-1.41.62.1-2.12.1-1.81.7-1.71.9-1.9-0.6-0.70.7
Intermittent access intake escalation4.54.46.7-1.91.9-2.12.3-2.32.32.1-2.12.2-1.82.12.6-2.62.6-2.32.2-2.22.4-2.4-0.8-1.01.0
Intermittent access intake escalation 22.02.04.1-0.90.9-1.11.7-1.71.71.3-1.21.7-0.81.12.0-2.02.0-1.51.3-1.31.8-1.80.2-0.10.0
Intermitt. access day 1 inactive lever presses0.50.51.20.8-0.90.8-0.40.4-0.4-0.70.7-0.60.9-0.7-0.40.4-0.40.6-0.70.7-0.70.71.10.8-0.8
Intermitt. access day 15 inactive lever presses1.41.53.21.4-1.51.5-0.50.5-0.5-1.31.3-0.81.5-1.4-0.80.8-0.81.2-1.41.4-1.01.01.71.8-1.8
Intermitt. access escalation Index0.20.20.4-0.30.3-0.30.5-0.50.50.4-0.40.5-0.20.10.6-0.60.6-0.40.3-0.30.5-0.50.50.1-0.1
Intermittent access day 1 total infusions3.03.44.72.0-2.02.0-2.12.1-2.1-2.02.0-1.81.8-1.8-2.22.2-2.22.0-1.91.9-1.81.80.10.8-0.8
Intermittent access day 15 total infusions0.00.00.20.1-0.10.0-0.00.0-0.0-0.00.00.10.10.0-0.00.0-0.00.0-0.00.00.1-0.1-0.40.0-0.0
Intermittent access terminal intake (last 3 days)0.30.40.70.8-0.80.8-0.40.4-0.4-0.70.7-0.30.8-0.7-0.30.3-0.40.6-0.70.7-0.30.30.60.8-0.8
Intermittent access total infusions0.20.30.40.7-0.70.6-0.50.5-0.5-0.60.6-0.30.6-0.6-0.50.5-0.50.5-0.60.6-0.30.30.00.4-0.4
Intermittent access day 1 locomotion0.40.40.90.3-0.20.2-1.01.0-1.0-0.50.5-0.90.2-0.2-0.90.9-0.90.6-0.40.4-0.90.9-0.3-0.50.5
Intermittent access day 15 total locomotion0.20.20.9-0.20.3-0.2-0.60.6-0.6-0.0-0.0-0.5-0.30.3-0.50.5-0.50.20.0-0.0-0.30.3-1.0-0.90.9
Intermittent access total locomotion0.30.31.20.1-0.0-0.0-0.80.8-0.8-0.20.2-0.7-0.10.1-0.60.6-0.60.3-0.10.1-0.50.5-1.1-1.01.0
Intermittent access standard deviation0.10.10.3-0.20.2-0.30.4-0.40.40.3-0.30.4-0.10.20.6-0.60.6-0.40.3-0.30.5-0.5-0.3-0.10.1
Left kidney weight0.20.62.1-0.50.5-0.60.1-0.10.10.7-0.70.1-0.80.80.6-0.60.5-0.80.9-0.90.8-0.8-1.0-1.41.4
Right kidney weight0.20.61.70.9-0.80.4-1.21.2-1.3-0.60.6-1.30.5-0.4-0.50.5-0.40.3-0.20.2-0.40.4-0.1-1.01.0
Cocaine induced anxiety3.64.18.92.5-2.62.4-0.90.9-0.9-2.12.2-1.12.7-2.4-1.11.1-1.11.8-2.22.2-1.41.43.02.9-2.9
Post-drug Anxiety1.41.53.41.4-1.51.5-0.60.6-0.6-1.31.3-0.61.5-1.5-0.80.8-0.81.2-1.41.4-0.90.91.51.8-1.8
Baseline Anxiety2.12.27.4-1.81.9-1.70.6-0.60.61.5-1.50.8-2.01.70.6-0.60.6-1.31.5-1.51.0-1.0-2.7-2.22.2
Tail length1.85.57.8-2.62.6-2.82.0-2.02.02.5-2.51.9-2.52.62.6-2.62.6-2.52.6-2.62.2-2.2-1.7-1.91.9
Length with tail0.10.31.0-0.30.3-0.8-0.10.1-0.10.4-0.40.1-0.40.60.5-0.50.5-0.50.6-0.60.6-0.6-0.7-1.01.0
Length without tail1.73.65.32.3-2.32.0-2.32.3-2.3-2.12.1-2.12.0-1.9-2.12.1-2.11.9-1.81.8-1.71.70.70.5-0.5
Times rat made contact with spout0.20.30.6-0.70.7-0.70.3-0.30.30.6-0.6-0.0-0.70.80.4-0.40.4-0.50.6-0.60.0-0.0-0.8-0.60.6
Lifetime Intake0.30.30.70.8-0.80.7-0.50.5-0.5-0.70.7-0.30.7-0.7-0.50.5-0.50.6-0.60.6-0.30.30.40.6-0.6
Liver weight, left0.20.41.60.8-0.80.7-0.10.1-0.0-0.60.6-0.30.8-0.8-0.50.5-0.40.4-0.60.6-0.30.31.30.9-0.9
Liver weight, right0.10.10.90.4-0.40.5-0.00.0-0.0-0.20.2-0.20.3-0.4-0.20.2-0.20.1-0.20.2-0.00.00.90.3-0.3
Locomotor activity0.30.41.10.4-0.40.3-0.90.9-0.9-0.50.5-1.00.3-0.5-1.01.0-1.00.5-0.40.4-0.60.6-0.6-0.40.4
Locomotor testing distance0.20.41.00.5-0.50.5-0.40.4-0.5-0.60.6-0.50.6-0.7-1.01.0-1.00.7-0.70.7-0.60.60.10.6-0.5
Locomotor testing rearing0.20.41.7-0.0-0.0-0.20.8-0.80.70.3-0.30.70.10.00.8-0.80.8-0.50.3-0.30.7-0.71.30.7-0.7
Locomotion in novel chamber0.60.71.91.2-1.10.8-1.21.2-1.2-0.90.9-1.40.9-0.7-0.70.7-0.70.6-0.60.5-0.60.60.3-0.40.4
Locomotion in novel chamber post-restriction0.30.31.0-0.60.6-0.80.1-0.10.00.5-0.50.3-0.60.80.4-0.40.4-0.50.6-0.60.5-0.5-1.0-0.80.8
Fecal boli incidents, locomotor time 10.70.72.0-0.50.5-0.51.2-1.21.20.7-0.71.4-0.50.40.9-0.90.9-0.90.7-0.71.3-1.30.40.2-0.2
Change in fecal boli incidents, locomotor task0.10.10.60.2-0.20.30.3-0.30.3-0.10.1-0.00.3-0.20.2-0.20.20.1-0.20.2-0.20.20.80.6-0.6
Time >=10cm from walls, locomotor time 10.50.52.1-0.50.6-0.8-0.20.2-0.20.5-0.5-0.1-0.70.70.3-0.30.3-0.60.7-0.70.5-0.5-1.2-1.41.4
Bouts of movement, locomotor time 11.01.12.6-1.11.0-0.71.6-1.61.61.0-1.01.6-0.90.81.0-1.01.0-0.90.7-0.71.0-1.0-0.10.4-0.4
Total resting periods, locomotor time 10.60.62.1-0.80.7-0.31.3-1.31.30.7-0.61.4-0.60.40.6-0.60.6-0.50.3-0.30.7-0.7-0.00.7-0.7
Rest time, locomotor task time 10.70.81.6-1.11.1-0.71.2-1.21.20.9-0.91.2-0.90.90.8-0.80.8-0.70.6-0.60.7-0.7-0.90.1-0.1
Distance moved, locomotor task time 10.80.81.41.0-1.00.9-0.80.8-0.8-0.90.9-0.70.9-1.1-1.11.1-1.10.9-0.90.9-0.80.81.20.6-0.6
Vertical activity count, locomotor time 10.30.30.5-0.40.4-0.60.3-0.30.30.5-0.50.3-0.40.40.6-0.60.6-0.70.7-0.70.7-0.70.2-0.60.6
Time >=10cm from walls, locomotor time 20.40.41.30.00.0-0.1-0.90.9-0.9-0.10.1-1.1-0.10.3-0.20.2-0.20.20.1-0.1-0.60.6-1.2-1.11.1
Bouts of movement, locomotor time 20.10.10.40.0-0.00.40.1-0.10.1-0.20.2-0.10.2-0.2-0.30.3-0.30.4-0.40.4-0.40.4-0.10.6-0.6
Total resting periods, locomotor time 20.10.10.8-0.10.10.30.4-0.40.4-0.10.10.30.1-0.1-0.10.1-0.10.2-0.30.3-0.10.10.20.9-0.9
Rest time, locomotor task time 20.60.72.8-0.50.40.21.5-1.51.50.4-0.31.4-0.2-0.00.3-0.30.3-0.1-0.10.10.5-0.50.21.7-1.6
Distance moved, locomotor task time 21.41.63.91.3-1.20.8-1.91.9-1.9-1.21.2-2.00.9-0.9-1.41.4-1.41.0-0.80.8-1.31.30.0-0.80.8
Vertical activity count, locomotor time 20.30.31.60.3-0.3-0.3-0.60.6-0.60.1-0.1-0.70.00.20.4-0.40.4-0.40.5-0.50.2-0.20.2-1.31.2
Light reinforcement 113.023.732.1-4.94.9-5.05.2-5.25.15.2-5.25.2-4.74.95.7-5.75.5-5.35.0-5.05.2-5.2-1.1-2.52.5
Light reinforcement 210.514.017.7-4.03.9-4.04.1-4.14.04.0-4.04.2-3.73.94.2-4.24.1-3.93.8-3.83.9-3.9-1.2-1.71.7
Bone: marrow area0.10.20.40.5-0.50.3-0.50.5-0.5-0.60.6-0.30.6-0.5-0.40.4-0.40.5-0.50.5-0.50.50.30.4-0.4
Bone: maximum diameter0.40.81.31.0-1.00.7-1.21.2-1.2-1.01.0-0.91.0-0.9-0.80.8-0.80.9-0.90.9-0.90.90.40.4-0.4
Bone: maximum force0.30.61.1-1.01.0-1.10.5-0.50.50.9-0.90.1-0.90.80.7-0.70.6-0.80.9-0.90.3-0.3-1.0-0.80.8
Bone: maximum moment0.10.20.6-0.60.6-0.70.2-0.20.20.5-0.5-0.1-0.60.50.4-0.40.4-0.50.6-0.60.0-0.0-0.8-0.70.7
Mean time between licks in bursts0.60.92.01.4-1.40.9-1.21.2-1.2-1.11.1-0.81.2-1.1-0.70.7-0.60.8-0.80.8-0.30.31.00.1-0.1
Mean num. licks in bursts0.10.10.7-0.20.2-0.0-0.20.2-0.1-0.10.1-0.6-0.10.2-0.30.3-0.40.3-0.20.2-0.70.7-0.9-0.10.1
Cd content in liver0.60.72.91.1-1.11.1-0.20.2-0.2-0.80.8-0.41.1-1.0-0.20.2-0.20.6-0.80.8-0.40.41.71.2-1.2
Co content in liver0.10.10.40.3-0.30.3-0.50.5-0.5-0.20.2-0.50.1-0.2-0.30.3-0.30.1-0.10.1-0.10.1-0.4-0.60.6
Cu content in liver0.10.10.20.4-0.40.4-0.40.4-0.4-0.30.3-0.40.2-0.2-0.10.1-0.10.2-0.20.2-0.30.30.1-0.10.1
Fe content in liver1.82.26.4-1.91.9-1.70.8-0.80.81.5-1.60.6-1.91.80.9-0.90.9-1.31.5-1.50.8-0.8-2.5-1.92.0
K content in liver0.20.20.70.2-0.10.1-0.70.7-0.7-0.10.1-0.7-0.1-0.1-0.30.3-0.30.10.0-0.0-0.20.2-0.6-0.90.9
Mg content in liver0.70.82.10.9-0.90.9-1.21.2-1.2-0.80.8-1.50.7-0.7-0.70.7-0.70.8-0.70.7-1.01.0-0.0-0.20.2
Mn content in liver0.80.92.11.0-1.01.4-0.70.7-0.7-1.01.0-0.70.9-1.2-1.01.0-1.01.1-1.11.1-0.90.90.40.8-0.8
Na content in liver0.40.41.7-0.60.6-0.8-0.30.3-0.30.4-0.4-0.1-0.70.70.1-0.10.1-0.30.5-0.50.1-0.1-1.3-1.21.2
Rb content in liver1.11.43.0-1.21.2-1.30.5-0.50.51.2-1.2-0.2-1.31.41.2-1.21.2-1.21.4-1.40.6-0.6-1.4-1.71.7
Se content in liver2.93.65.3-2.12.2-2.31.1-1.11.12.0-2.00.8-2.22.31.8-1.81.7-1.92.1-2.11.3-1.3-2.2-2.32.3
Sr content in liver0.10.10.40.1-0.0-0.2-0.30.3-0.30.1-0.1-0.3-0.10.20.2-0.20.2-0.20.3-0.30.3-0.3-0.1-0.60.6
Zn content in liver3.33.65.52.1-2.22.4-1.51.5-1.5-2.12.1-1.52.2-2.0-1.71.7-1.72.0-2.12.1-2.02.01.51.9-1.9
Bone: minimum diameter1.02.02.6-1.51.5-1.51.2-1.21.21.5-1.51.4-1.51.61.5-1.51.5-1.41.5-1.51.4-1.4-0.9-1.01.0
Time in familiar zone, hab. session 10.60.61.0-0.50.5-0.80.5-0.50.50.7-0.70.7-0.60.81.0-1.01.0-0.90.9-0.91.0-1.0-0.0-0.80.7
Time in novel zone, hab. session 10.30.30.8-0.00.10.4-0.30.3-0.3-0.30.3-0.50.0-0.3-0.90.9-0.90.6-0.50.5-0.70.7-0.80.3-0.2
Total zone transitions, hab. session 10.20.30.50.6-0.70.6-0.50.5-0.5-0.60.6-0.60.7-0.6-0.60.6-0.60.6-0.60.6-0.50.50.50.6-0.6
Total locomotion distance, hab. session 10.50.81.40.8-0.81.1-0.50.5-0.5-0.90.9-0.50.9-1.0-0.90.9-0.90.9-1.01.0-0.80.80.71.2-1.2
Locomotion velocity, hab. session 10.60.81.50.9-0.91.1-0.50.5-0.5-0.90.9-0.51.0-1.0-0.90.9-0.90.9-1.01.0-0.80.80.91.2-1.2
Time in familiar zone, hab. session 20.91.02.2-0.60.6-0.61.4-1.41.40.8-0.81.5-0.40.51.2-1.21.2-0.90.7-0.71.2-1.21.00.6-0.6
Time in novel zone, hab. session 22.02.03.21.1-1.11.4-1.61.6-1.6-1.31.3-1.81.0-1.1-1.81.8-1.81.5-1.31.3-1.81.8-0.60.2-0.2
Total zone transitions, hab. session 20.10.10.50.3-0.30.20.1-0.10.1-0.20.2-0.20.4-0.30.1-0.10.10.2-0.20.2-0.30.30.70.6-0.6
Total locomotion distance, hab. session 20.10.20.70.3-0.30.50.1-0.10.1-0.30.3-0.10.4-0.4-0.10.1-0.10.4-0.40.4-0.40.40.60.8-0.8
Locomotion velocity, hab. session 20.00.00.2-0.10.10.10.3-0.30.30.0-0.00.10.00.00.2-0.20.20.0-0.10.1-0.20.20.30.5-0.5
Novel to familiar place preference ratio0.90.91.60.8-0.70.9-0.80.8-0.8-0.90.9-1.10.8-0.9-1.31.3-1.31.1-1.01.0-1.31.3-0.10.6-0.5
Novelty place preference0.60.61.30.5-0.50.7-0.60.6-0.6-0.70.7-0.80.6-0.8-1.11.1-1.10.9-0.80.8-1.11.1-0.20.5-0.5
Time in novel zone, NPP test0.60.61.30.4-0.30.4-0.80.8-0.8-0.60.6-1.00.4-0.5-1.11.1-1.10.8-0.70.7-1.11.1-0.70.1-0.1
Total zone transitions, NPP test0.10.10.40.6-0.60.4-0.30.3-0.3-0.30.3-0.60.4-0.30.1-0.10.10.1-0.20.2-0.10.10.70.0-0.0
Total locomotion distance, NPP test0.10.10.50.3-0.30.4-0.40.4-0.4-0.30.3-0.70.2-0.1-0.20.2-0.20.3-0.30.3-0.60.6-0.1-0.00.0
Locomotion velocity, NPP test0.00.00.20.3-0.30.4-0.10.1-0.1-0.20.2-0.30.2-0.10.2-0.20.20.1-0.20.2-0.20.20.40.2-0.2
Intraocular pressure5.07.08.92.7-2.72.9-2.32.3-2.4-2.92.9-2.22.8-2.7-2.82.8-2.82.9-3.03.0-2.72.71.52.4-2.4
Delta distance traveled before/after self-admin1.41.51.9-1.41.4-1.31.1-1.11.11.3-1.31.2-1.41.21.1-1.11.1-1.31.3-1.31.3-1.3-0.9-1.01.0
Delta ambulatory time before/after self-admin2.02.22.6-1.51.5-1.51.5-1.51.51.6-1.61.5-1.61.41.5-1.51.5-1.61.6-1.61.6-1.6-0.7-1.11.1
Parametrial fat weight0.10.31.10.9-0.90.5-0.60.6-0.7-0.50.5-0.40.7-0.7-0.10.1-0.10.2-0.20.2-0.10.11.0-0.10.1
Pavlov. Cond. lever latency0.10.10.60.3-0.40.30.2-0.20.2-0.20.20.30.4-0.4-0.10.1-0.10.2-0.30.30.1-0.10.80.6-0.6
Pavlov. Cond. magazine entry latency0.10.10.6-0.10.1-0.0-0.40.4-0.4-0.0-0.0-0.3-0.20.0-0.50.5-0.50.10.0-0.0-0.10.1-0.8-0.50.5
Pavlov. Cond. change in total contacts1.41.52.8-1.51.5-1.60.6-0.60.61.3-1.30.3-1.41.61.0-1.01.0-1.11.3-1.30.6-0.6-1.7-1.41.4
Pavlov. Cond. index score0.10.10.40.1-0.00.1-0.60.6-0.6-0.20.1-0.60.0-0.1-0.40.4-0.40.2-0.10.1-0.30.3-0.6-0.40.4
Pavlov. Cond. latency score0.00.10.10.1-0.10.2-0.40.4-0.4-0.20.2-0.40.1-0.1-0.30.3-0.30.2-0.20.2-0.30.3-0.2-0.10.1
Pavlov. Cond. lever contacts0.20.21.2-0.30.4-0.5-0.50.5-0.50.2-0.2-0.7-0.40.50.0-0.00.0-0.10.3-0.3-0.30.3-1.1-0.90.9
Pavlov. Cond. magazine entry number0.30.41.60.3-0.30.50.7-0.70.7-0.20.20.70.4-0.40.3-0.30.30.1-0.30.30.1-0.11.31.2-1.2
Pavlov. Cond. intertrial magazine entries0.20.20.50.6-0.60.7-0.30.3-0.3-0.50.5-0.40.5-0.5-0.20.2-0.20.4-0.40.4-0.40.40.60.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.2-0.20.2-0.70.7-0.7-0.30.3-0.80.1-0.2-0.60.6-0.60.3-0.20.2-0.50.5-0.6-0.40.4
Pavlov. Cond. response bias0.60.73.6-0.50.5-0.7-0.90.9-0.90.2-0.2-1.1-0.60.7-0.20.2-0.2-0.10.4-0.4-0.50.5-1.9-1.61.6
Pavlov. Cond. lever latency0.10.20.50.1-0.10.60.2-0.20.2-0.20.2-0.10.2-0.5-0.60.6-0.60.4-0.50.5-0.60.60.10.7-0.7
Pavlov. Cond. magazine entry latency0.10.10.20.4-0.4-0.0-0.50.5-0.5-0.20.2-0.30.3-0.00.2-0.20.2-0.00.0-0.00.2-0.20.4-0.30.3
Pavlov. Cond. change in total contacts0.20.21.20.00.0-0.5-0.50.5-0.50.1-0.1-0.6-0.20.50.4-0.40.4-0.30.4-0.40.1-0.1-0.4-1.11.1
Pavlov. Cond. index score0.10.10.60.2-0.2-0.3-0.60.6-0.6-0.00.0-0.50.00.30.2-0.20.2-0.10.2-0.20.2-0.2-0.2-0.80.8
Pavlov. Cond. latency score0.10.10.60.1-0.1-0.3-0.50.5-0.50.0-0.0-0.3-0.00.30.3-0.30.3-0.20.3-0.30.3-0.3-0.2-0.80.8
Pavlov. Cond. lever contacts0.40.51.1-0.40.4-0.90.2-0.20.20.6-0.60.4-0.50.91.0-1.01.0-0.80.9-0.90.9-0.9-0.1-1.00.9
Pavlov. Cond. magazine entry number0.10.10.5-0.40.4-0.00.7-0.70.70.3-0.30.6-0.30.10.1-0.10.1-0.20.1-0.10.1-0.10.10.4-0.4
Pavlov. Cond. intertrial magazine entries0.50.61.6-0.80.7-0.51.3-1.31.30.8-0.81.1-0.70.50.8-0.80.8-0.80.6-0.60.8-0.80.20.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.10.20.70.2-0.2-0.3-0.60.6-0.6-0.10.1-0.50.10.30.3-0.30.3-0.10.2-0.20.1-0.1-0.2-0.80.8
Pavlov. Cond. response bias0.20.21.00.1-0.0-0.6-0.50.5-0.50.1-0.2-0.4-0.10.50.5-0.50.5-0.40.5-0.50.4-0.4-0.2-1.01.0
Time in closed arm before self-admin3.74.15.7-2.22.2-2.41.6-1.61.62.2-2.21.6-2.22.32.0-2.02.0-2.22.3-2.32.0-2.0-1.5-2.02.0
Time in closed arm after self-admin1.31.33.7-1.41.5-1.50.6-0.60.61.2-1.20.5-1.41.50.8-0.80.8-1.01.2-1.20.6-0.6-1.9-1.51.5
Time in open arm before self-admin3.23.54.82.2-2.22.0-1.91.9-1.9-2.12.1-2.02.1-2.0-1.81.8-1.81.9-1.91.9-1.81.81.21.1-1.1
Time in open arm after self-admin0.70.81.21.1-1.11.0-0.90.9-0.9-1.01.0-0.91.0-1.0-0.80.8-0.80.9-0.90.9-0.70.70.90.6-0.6
Bone: periosteal estimation0.00.00.0-0.00.0-0.2-0.10.1-0.10.0-0.00.10.00.10.2-0.20.2-0.00.0-0.0-0.00.0-0.00.0-0.1
Bone: periosteal perimeter0.30.60.90.8-0.90.6-0.60.6-0.6-0.90.9-0.51.0-0.7-0.50.5-0.50.8-0.80.8-0.80.80.80.9-0.9
Bone: post-yield work0.10.20.8-0.10.1-0.30.0-0.00.0-0.30.3-0.40.3-0.1-0.10.1-0.10.4-0.40.4-0.80.8-0.00.9-0.9
Progressive ratio test 1 active lever presses1.11.22.31.0-0.90.7-1.51.5-1.5-1.01.0-1.40.8-0.6-1.31.3-1.31.0-0.80.8-1.21.2-0.8-0.50.5
Progressive ratio test 1 breakpoint0.70.81.50.7-0.70.5-1.21.2-1.2-0.80.8-1.20.5-0.4-1.11.1-1.10.8-0.60.6-0.90.9-0.9-0.60.6
Progressive ratio test 1 inactive lever presses0.20.20.40.7-0.60.4-0.60.6-0.6-0.50.5-0.60.5-0.3-0.40.4-0.40.4-0.30.3-0.40.4-0.2-0.20.2
Progressive ratio test 2 active lever presses0.30.30.50.7-0.60.6-0.70.7-0.7-0.60.6-0.60.5-0.5-0.70.7-0.70.5-0.50.5-0.50.5-0.1-0.10.1
Progressive ratio test 2 breakpoint0.40.40.60.8-0.80.7-0.80.8-0.8-0.70.7-0.70.7-0.7-0.80.8-0.80.7-0.60.6-0.60.60.00.1-0.1
Progressive ratio test 2 inactive lever presses2.83.34.42.1-2.12.0-1.71.7-1.7-2.02.0-1.82.0-1.9-1.71.7-1.71.9-1.91.9-1.81.81.31.4-1.4
Incentive Sensitization - Responses0.10.10.60.3-0.40.40.2-0.20.2-0.20.20.20.3-0.5-0.00.0-0.00.1-0.20.20.1-0.10.80.6-0.6
Incentive Sensitization - Breakpoint0.10.10.60.2-0.30.30.3-0.30.3-0.10.10.30.2-0.40.1-0.10.10.0-0.20.20.2-0.20.70.6-0.6
Sum of active levers in priming session hrs 5-60.20.21.00.1-0.20.20.5-0.50.5-0.00.10.30.2-0.30.2-0.20.20.0-0.20.20.0-0.01.00.9-0.9
Progressive ratio0.30.30.9-0.70.7-0.30.9-0.90.90.4-0.40.9-0.40.20.5-0.50.5-0.20.1-0.10.1-0.10.20.7-0.7
Food seeking constrained by brief footshock1.92.33.9-1.71.6-1.72.0-2.01.91.6-1.61.6-1.41.41.7-1.71.7-1.61.5-1.51.3-1.30.0-0.20.1
Seeking ratio, punishment vs. effort0.60.81.6-0.70.7-1.10.5-0.50.50.9-0.90.3-0.81.00.8-0.80.8-1.11.1-1.20.9-0.9-0.6-1.31.2
Retroperitoneal fat weight0.82.85.52.3-2.32.2-1.11.1-1.1-1.81.8-1.12.1-2.1-1.11.1-1.11.5-1.71.7-1.01.02.41.7-1.7
Reaction time number correct0.71.01.70.9-0.91.2-1.01.0-1.0-1.01.0-1.30.9-1.0-1.21.2-1.21.1-1.01.0-1.31.30.00.5-0.5
Reaction time mean minus median0.70.93.00.7-0.60.4-1.41.4-1.4-0.80.8-1.70.5-0.4-0.90.9-0.90.8-0.60.6-1.31.3-1.0-0.70.7
Reaction time mean minus median AUC0.70.92.30.8-0.80.7-1.41.4-1.4-0.90.9-1.50.7-0.5-0.90.9-1.00.9-0.70.7-1.21.2-0.7-0.40.4
Reaction time num false alarms5.98.111.83.4-3.43.1-3.03.0-2.9-3.13.1-2.93.2-3.0-2.72.7-2.82.8-2.82.8-2.62.62.01.7-1.7
Reaction time num false alarms AUC5.27.210.23.2-3.22.9-2.72.7-2.7-2.92.9-2.83.0-2.9-2.72.7-2.72.7-2.72.7-2.62.61.91.7-1.7
Reaction time trials correct on left0.71.01.70.9-0.91.2-1.01.0-1.0-1.01.0-1.30.9-1.0-1.21.2-1.21.1-1.01.0-1.31.30.00.5-0.5
Reaction time trials on left0.91.22.01.1-1.01.3-1.11.1-1.2-1.11.1-1.41.0-1.1-1.31.3-1.31.2-1.11.1-1.41.40.00.5-0.5
Reaction time mean1.52.14.11.4-1.31.3-2.02.0-2.0-1.51.4-2.01.1-0.9-1.51.5-1.51.4-1.21.2-1.61.6-0.8-0.50.5
Reaction time mean AUC1.62.24.31.5-1.41.3-2.12.1-2.0-1.51.5-2.01.2-1.0-1.61.6-1.61.5-1.31.3-1.61.6-0.7-0.30.4
Median of all reaction times1.41.93.71.4-1.41.3-1.91.9-1.9-1.41.4-1.81.1-1.0-1.51.5-1.51.4-1.21.2-1.41.4-0.6-0.30.3
Reaction time omissions1.92.65.01.9-1.81.5-2.22.2-2.2-1.71.7-1.91.5-1.5-1.61.6-1.71.6-1.41.4-1.41.40.4-0.00.0
Reaction time false alarm rate2.23.15.12.3-2.31.8-1.81.8-1.8-2.02.0-1.62.1-1.9-1.61.6-1.61.7-1.81.8-1.41.41.61.2-1.2
Reaction time premature initiation rate2.83.86.9-1.41.3-1.42.5-2.52.61.8-1.72.5-1.31.32.6-2.62.6-2.01.7-1.72.4-2.41.50.1-0.2
Reaction time premature initiations0.91.32.8-0.60.6-0.61.6-1.61.70.9-0.91.5-0.50.51.6-1.61.5-1.10.8-0.81.3-1.31.40.5-0.5
Std. dev. reaction times0.91.23.31.0-1.00.7-1.61.6-1.6-1.11.1-1.80.8-0.6-1.01.0-1.01.0-0.80.8-1.31.3-0.7-0.50.5
Reaction time trials completed0.91.22.01.1-1.01.3-1.11.1-1.2-1.11.1-1.41.0-1.1-1.31.3-1.31.2-1.11.1-1.41.40.00.5-0.5
Reaction time trials AUC0.91.32.11.1-1.01.3-1.11.1-1.2-1.11.1-1.41.0-1.1-1.31.3-1.31.2-1.11.1-1.41.40.00.5-0.5
Run reversals in cocaine runway, females0.90.92.10.9-0.80.7-1.31.3-1.4-0.90.9-1.40.8-0.8-1.01.0-1.00.9-0.80.8-1.11.1-0.3-0.00.0
Run reversals in cocaine runway, males0.10.10.4-0.10.20.1-0.00.0-0.10.0-0.0-0.3-0.2-0.1-0.40.4-0.40.1-0.10.1-0.20.2-0.6-0.10.1
Latency to leave start box in cocaine runway0.10.20.50.3-0.40.5-0.10.1-0.1-0.40.4-0.10.4-0.3-0.30.3-0.30.5-0.50.5-0.40.40.40.7-0.7
Latency to leave start box in cocaine runway, F0.30.30.80.0-0.00.3-0.40.4-0.5-0.40.4-0.50.1-0.1-0.80.8-0.80.7-0.50.5-0.80.8-0.90.2-0.2
Latency to leave start box in cocaine runway, M1.00.93.5-0.10.1-0.41.2-1.21.30.6-0.51.2-0.00.41.3-1.31.4-0.90.6-0.61.1-1.11.90.7-0.7
Std. dev. time between licks in bursts0.30.31.0-0.20.2-0.20.5-0.50.50.5-0.50.8-0.40.20.6-0.60.6-0.60.5-0.51.0-1.00.4-0.40.4
Total sessions with >9 infusions0.60.61.00.9-0.90.7-1.01.0-1.0-0.90.8-0.90.8-0.7-0.90.9-0.90.8-0.80.8-0.90.90.30.2-0.2
Short access day 1 total inactive lever presses0.10.20.4-0.10.1-0.30.5-0.50.50.3-0.30.3-0.20.30.6-0.60.6-0.50.4-0.40.5-0.50.2-0.20.2
Short access day 10 total inactive lever presses0.30.41.5-0.0-0.0-0.10.7-0.70.70.3-0.30.70.0-0.00.8-0.80.8-0.50.3-0.30.7-0.71.20.5-0.5
Short access day 1 total infusions1.92.02.51.6-1.61.4-1.61.6-1.6-1.51.5-1.51.5-1.4-1.41.4-1.41.5-1.41.4-1.51.50.90.7-0.7
Short access day 10 total infusions0.30.30.60.7-0.80.7-0.20.2-0.2-0.60.6-0.20.7-0.7-0.50.5-0.50.5-0.60.6-0.20.20.40.7-0.7
Short access total infusions0.10.10.30.5-0.50.4-0.30.3-0.3-0.40.4-0.20.4-0.3-0.30.3-0.30.3-0.30.3-0.20.20.00.2-0.2
Short access day 1 locomotion1.81.92.71.3-1.31.3-1.51.5-1.5-1.41.4-1.61.3-1.3-1.51.5-1.51.5-1.41.4-1.71.70.70.8-0.7
Short access day 10 total locomotion0.20.30.50.5-0.50.5-0.70.7-0.7-0.50.5-0.60.5-0.4-0.60.6-0.60.5-0.50.5-0.50.50.20.1-0.1
Short access total locomotion0.70.81.20.8-0.70.8-1.01.0-1.0-0.90.9-1.00.7-0.8-1.01.0-1.01.0-0.90.9-1.11.10.20.4-0.3
One hour access (0.3 mA shock)0.70.83.30.8-0.90.90.1-0.10.1-0.70.70.21.0-1.0-0.20.2-0.20.6-0.90.9-0.10.11.71.8-1.8
Compulsive drug intake0.90.91.6-1.11.1-0.81.3-1.31.31.0-1.01.2-0.90.81.0-1.01.0-0.80.7-0.70.8-0.80.10.4-0.4
One hour access (shock baseline)1.41.62.21.4-1.51.5-0.90.9-0.9-1.41.4-0.81.5-1.5-1.11.1-1.11.3-1.41.4-0.90.91.31.5-1.5
Social response proportion0.10.10.7-0.00.10.1-0.30.3-0.40.1-0.1-0.1-0.30.10.0-0.0-0.0-0.10.2-0.20.2-0.2-0.7-0.80.8
Social responses0.50.72.31.1-1.21.0-0.50.5-0.5-0.80.9-0.21.1-1.0-0.30.3-0.30.6-0.80.8-0.20.21.51.0-1.0
Social time1.21.62.8-1.51.5-1.11.4-1.41.41.4-1.41.7-1.51.21.2-1.21.1-1.31.3-1.31.5-1.5-0.5-0.80.8
Soleus weight0.10.41.00.6-0.70.6-0.10.1-0.1-0.60.60.50.7-0.9-0.60.6-0.60.5-0.60.60.1-0.11.01.0-1.0
Bone: stiffness0.40.62.0-0.80.9-1.2-0.00.0-0.00.7-0.7-0.4-0.80.90.6-0.60.5-0.60.8-0.80.0-0.0-1.4-1.21.2
Tibialis anterior weight0.51.52.51.1-1.11.2-1.51.5-1.5-1.21.2-1.60.9-1.0-1.51.5-1.51.3-1.11.1-1.51.5-0.50.0-0.0
Time to tail flick, vehicle, before self-admin0.40.42.3-0.30.20.20.9-0.90.90.1-0.11.00.0-0.20.1-0.10.20.1-0.30.30.2-0.20.91.5-1.5
Time to tail flick, vehicle, after self-admin0.60.71.7-0.40.3-0.31.2-1.21.20.5-0.51.3-0.20.20.9-0.90.9-0.50.3-0.30.9-0.91.20.9-0.9
Time to tail flick, test, before self-admin0.50.50.70.7-0.80.8-0.50.5-0.5-0.80.8-0.60.8-0.7-0.70.7-0.70.8-0.80.8-0.80.80.50.7-0.7
Time to tail flick, test, after self-admin0.50.50.8-0.90.9-0.80.8-0.80.80.8-0.80.7-0.80.80.7-0.70.7-0.70.7-0.70.6-0.6-0.4-0.30.3
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.10.0-0.30.5-0.50.50.3-0.30.5-0.10.20.6-0.60.6-0.50.4-0.40.7-0.70.6-0.10.1
Delta time to tail flick, test, before/after SA1.41.32.9-1.31.4-1.40.4-0.40.41.2-1.20.4-1.41.40.8-0.80.8-1.01.2-1.20.8-0.8-1.6-1.71.7
Tibia length0.41.25.0-0.20.3-1.0-1.51.5-1.50.0-0.0-1.6-0.40.8-0.50.5-0.50.00.4-0.4-0.60.6-2.2-2.02.0
Ambulatory time before self-admin1.01.12.30.8-0.80.6-1.51.5-1.5-1.00.9-1.50.7-0.6-1.21.2-1.21.0-0.80.8-1.21.2-0.9-0.40.4
Ambulatory time after self-admin1.51.74.0-1.51.5-1.50.7-0.70.71.4-1.40.7-1.61.50.9-0.90.9-1.21.4-1.40.9-0.9-2.0-1.71.7
Bone: tissue strength0.30.30.7-0.50.5-0.40.3-0.30.30.6-0.60.5-0.70.50.5-0.50.4-0.60.7-0.70.7-0.7-0.5-0.80.8
Total heroin consumption0.10.10.20.5-0.50.2-0.40.4-0.4-0.30.3-0.40.4-0.3-0.10.1-0.10.2-0.20.2-0.30.30.30.1-0.1
Bone: trabecular number1.93.06.5-2.32.3-1.52.6-2.62.61.9-1.92.0-1.91.51.3-1.31.4-1.51.4-1.41.1-1.1-1.10.0-0.0
Bone: trabecular spacing1.31.63.21.8-1.81.5-1.71.7-1.7-1.41.4-1.31.4-1.3-1.01.0-1.01.1-1.11.1-0.80.81.10.1-0.1
Bone: trabecular thickness4.04.88.4-2.92.9-2.52.2-2.22.22.5-2.51.7-2.72.51.8-1.81.8-2.12.2-2.21.5-1.5-2.4-1.51.5
Bone: trabecular tissue density0.30.41.70.5-0.50.3-0.90.9-0.9-0.50.5-1.30.5-0.2-0.60.6-0.70.6-0.40.4-1.11.1-0.3-0.20.2
Water consumed over 24 hours2.93.54.6-2.01.9-2.02.0-2.02.02.0-2.02.1-1.81.92.1-2.12.0-2.01.9-1.92.0-2.0-0.7-0.90.9
Number of responses in last shaping day5.45.66.92.6-2.62.6-2.22.2-2.2-2.62.6-2.32.6-2.6-2.22.2-2.22.5-2.52.5-2.52.51.51.9-1.9