Hub : Genes

Nkd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Nkd1 0.04 0.03 7.1e-05 0.04 0.05 0.04 0.05 6.5e-05 2.4e-05 5.8e-05 3.2e-05
2 PL mRNA stability Nkd1 0.02 0.02 4.7e-03 0.02 0.02 0.02 0.01 4.9e-03 4.9e-03 3.0e-03 1.1e-02
3 PL gene expression Nkd1 0.05 0.03 6.5e-06 0.05 0.04 0.03 0.04 7.2e-06 2.4e-05 5.4e-04 2.7e-05
4 Adipose gene expression Nkd1 0.15 0.08 0.0e+00 0.16 0.06 0.16 0 4.0e-17 3.6e-07 1.6e-17 2.0e-01
5 Brain mRNA stability Nkd1 0.08 0.04 4.4e-10 0.12 0.12 0.12 0.12 1.2e-11 5.0e-11 3.5e-11 1.9e-11
6 NAcc mRNA stability Nkd1 0.03 0.02 2.3e-04 0.03 0.02 0.02 0.02 2.8e-04 1.4e-03 3.0e-03 1.3e-03
7 Liver gene expression Nkd1 0.03 0.02 1.5e-04 0.04 0.02 0.02 0.03 8.8e-05 1.1e-03 1.1e-03 1.7e-04
8 BLA mRNA stability Nkd1 0.08 0.05 1.3e-04 0.07 0.06 0.07 0.07 1.2e-04 2.7e-04 1.7e-04 1.2e-04
9 pVTA gene expression Nkd1 0.24 0.13 1.4e-05 0.04 0.07 0.08 0.05 1.0e-02 7.5e-04 3.1e-04 2.8e-03
10 OFC mRNA stability Nkd1 0.19 0.12 4.8e-03 -0 0.02 0.01 0.03 4.4e-01 1.2e-01 2.3e-01 7.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.42.44.01.92.0-1.5-1.71.71.6-1.41.60.30.9
Area under the delay curve0.40.40.9-0.7-1.00.60.7-0.6-0.60.5-0.7-0.40.3
BMI with tail1.85.77.3-2.7-2.62.62.4-2.5-2.62.6-2.52.1-0.2
BMI without tail0.10.10.4-0.4-0.30.2-0.0-0.0-0.10.1-0.50.5-0.7
Body weight0.72.84.7-2.0-2.21.71.5-1.6-1.71.8-1.70.6-1.4
Weight adjusted by age3.94.45.9-2.4-2.32.02.0-2.4-2.42.4-2.02.0-0.4
Bone surface0.50.81.31.11.1-1.1-1.01.01.0-0.80.90.10.2
Bone volume1.52.53.51.81.8-1.9-1.91.81.7-1.51.7-0.5-0.2
Breakpoint value in progressive ratio session0.50.50.80.90.8-0.6-0.70.80.7-0.80.8-0.60.3
Number of licking bursts0.50.61.50.80.6-0.8-0.70.70.8-0.60.7-1.2-0.1
Context. condit. distance diff. score3.64.47.3-1.8-1.82.32.7-2.2-2.12.1-2.31.12.0
Locomotion velocity, session 10.80.92.90.50.4-0.9-0.61.11.1-1.20.4-1.7-0.9
Locomotion distance, session 10.00.00.20.20.40.00.10.10.2-0.20.1-0.10.4
Locomotion velocity, session 20.10.10.40.20.2-0.10.10.30.4-0.5-0.3-0.30.6
Locomotion distance, session 20.10.20.4-0.3-0.40.60.5-0.3-0.40.4-0.40.10.7
Locomotion velocity, session 32.22.53.5-1.9-1.81.71.7-1.7-1.71.5-1.61.3-0.5
Locomotion distance, session 30.50.51.0-0.9-1.00.80.8-0.6-0.70.7-0.6-0.3-0.7
Stereotopy head waving bouts, day 30.80.91.4-1.1-1.00.91.1-1.1-1.00.8-1.20.60.2
Stereotopy head waving duration, day 31.21.42.1-1.2-1.11.21.4-1.4-1.21.1-1.41.20.4
Locomotion velocity, session 71.51.73.9-0.7-0.51.31.4-1.2-1.21.1-1.11.72.0
Locomotion distance, session 70.50.64.30.80.7-0.0-0.10.30.3-0.20.40.42.1
Stereotopy head waving bouts, day 70.91.11.8-1.3-1.30.91.0-1.1-1.00.8-1.20.2-1.0
Stereotopy head waving duration, day 70.40.54.0-0.4-0.3-0.2-0.2-0.00.1-0.20.0-0.8-2.0
Locomotion velocity, session 81.11.44.4-0.6-0.41.11.5-0.9-1.01.0-1.11.12.1
Locomotion distance, session 81.42.04.1-1.0-1.01.52.0-1.4-1.41.4-1.40.42.0
Degree of sensitization distance0.80.84.81.00.9-0.3-0.30.40.4-0.40.40.82.2
Degree of sensitization stereotypy1.01.12.0-1.4-1.30.90.9-1.1-1.00.9-1.10.3-1.4
Conditioned locomotion0.10.10.30.30.3-0.2-0.50.20.3-0.20.6-0.2-0.1
Cocaine response after cond. corrected1.41.52.4-1.0-0.91.51.4-1.1-1.21.4-1.11.21.5
Cocaine response after cond. not corrected0.91.01.8-1.0-0.81.21.1-1.0-1.11.3-1.00.90.7
Cocaine response before conditioning1.41.73.40.90.9-1.6-1.41.11.2-1.01.1-1.7-1.8
Saline control response1.72.24.02.01.6-1.3-1.11.51.3-1.41.5-1.31.9
Bone: connectivity density1.52.44.82.02.2-1.3-1.51.41.3-1.11.51.01.8
Bone: cortical apparent density0.30.41.7-0.10.10.60.4-0.2-0.40.3-0.31.11.3
Bone: cortical area0.10.20.40.30.3-0.5-0.30.60.5-0.30.2-0.5-0.3
Bone: cortical porosity0.10.10.5-0.3-0.20.1-0.0-0.5-0.50.20.0-0.4-0.7
Bone: cortical porosity0.20.31.5-0.2-0.1-0.1-0.3-0.3-0.30.00.3-0.8-1.2
Bone: cortical thickness0.00.00.1-0.10.10.1-0.20.20.1-0.00.10.4-0.3
Bone: cortical thickness0.60.73.6-0.00.70.30.3-0.5-0.50.7-0.51.91.1
Bone: cortical tissue density0.30.42.0-0.10.10.60.4-0.2-0.40.4-0.41.11.4
Condit. Reinf. active minus inactive responses0.70.81.2-0.8-1.01.11.0-0.8-0.80.9-1.00.20.6
Condit. Reinf. active-inactive response ratio1.21.32.1-1.1-1.31.21.4-1.0-1.11.2-1.4-0.10.8
Condit. Reinf. active responses0.00.00.10.0-0.0-0.1-0.20.20.2-0.20.0-0.3-0.3
Condit. Reinf. inactive responses3.23.85.31.92.2-2.2-2.32.12.1-2.22.1-0.7-1.2
Incentive salience index mean0.30.31.60.50.3-0.5-0.40.60.6-0.50.4-1.30.0
Condit. Reinf. lever presses1.92.54.41.61.4-1.9-1.51.61.7-1.71.4-2.1-0.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.60.50.3-0.1-0.10.3-0.20.1-0.4
Condit. Reinf. active-inactive response ratio0.30.31.9-0.5-0.30.4-0.10.0-0.00.3-0.10.8-1.4
Condit. Reinf. active responses0.10.10.2-0.3-0.40.30.4-0.10.1-0.0-0.4-0.1-0.4
Condit. Reinf. inactive responses0.30.40.9-0.4-0.70.61.0-0.8-0.50.4-0.8-0.30.8
Condit. Reinf. lever presses0.50.71.3-0.9-1.10.91.0-0.9-0.70.7-0.90.5-0.0
Condit. Reinf. lever reinforcers received0.20.30.6-0.7-0.80.60.7-0.5-0.20.3-0.70.3-0.6
Conditioned reinforcement - actives0.80.81.3-0.9-1.00.91.1-1.0-1.01.0-1.00.50.4
Conditioned reinforcement - inactives1.01.12.2-1.0-1.11.01.5-1.0-1.01.1-1.50.00.1
Conditioned locomotion0.10.20.8-0.1-0.20.40.4-0.2-0.20.2-0.30.40.9
Patch foraging indifference point 0 sec0.81.32.3-1.0-1.41.11.5-1.1-1.11.0-1.5-0.40.9
Patch foraging indifference point AUC1.51.82.61.51.5-1.3-1.41.31.5-1.31.6-1.1-0.1
Delay disc. indifference point, 0s delay1.41.62.81.01.0-1.2-1.21.41.4-1.31.2-1.7-0.9
Delay disc. indifference point, 16s delay0.80.81.6-1.0-1.30.91.0-1.0-1.00.9-1.00.20.2
Delay disc. indifference point, 2s delay0.60.71.1-1.0-1.01.00.7-0.8-0.80.7-0.90.80.2
Delay disc. indifference point, 24s delay0.10.10.4-0.2-0.40.00.1-0.1-0.1-0.0-0.2-0.6-0.3
Delay disc. indifference point, 4s delay0.30.32.80.0-0.10.40.4-0.1-0.10.1-0.2-0.11.7
Delay disc. indifference point, 8s delay1.11.12.4-1.2-1.51.11.2-1.1-1.01.0-1.1-0.5-0.2
Indifference point function ln k1.62.23.1-1.5-1.31.51.6-1.4-1.61.6-1.81.60.6
Indifference point function log k1.62.23.1-1.5-1.31.51.6-1.4-1.61.6-1.81.60.6
Patch foraging total patch changes 0 sec1.01.72.9-1.1-1.61.21.7-1.3-1.31.2-1.7-0.30.9
Patch foraging total patch changes 12 sec0.81.02.41.20.9-0.6-0.61.01.1-0.80.8-1.51.1
Patch foraging total patch changes 18 sec1.92.53.71.91.8-1.5-1.41.71.7-1.71.6-1.21.0
Patch foraging total patch changes 24 sec0.70.83.40.90.6-0.8-0.20.90.9-0.80.6-1.80.6
Patch foraging total patch changes 6 sec0.20.21.60.40.1-0.4-0.20.10.3-0.30.2-1.30.1
Patch foraging time to switch 0 sec0.10.10.9-0.0-0.40.00.1-0.00.00.10.0-1.0-0.2
Patch foraging water rate 0 sec0.10.20.30.30.5-0.3-0.60.50.4-0.40.50.5-0.4
Patch foraging water rate 12 sec0.40.61.20.80.9-0.9-0.90.80.8-1.10.6-0.3-0.2
Patch foraging water rate 18 sec2.33.04.61.31.3-1.9-2.11.81.9-1.91.6-1.1-2.2
Patch foraging water rate 24 sec0.10.10.20.20.2-0.4-0.40.40.3-0.20.20.1-0.2
Patch foraging water rate 6 sec3.14.66.32.42.5-2.5-2.22.52.3-2.42.1-1.20.3
Seeking ratio, delayed vs. immediate footshock4.35.06.6-2.3-2.32.42.5-2.4-2.32.4-2.61.70.7
Distance traveled before self-admin1.11.21.8-1.4-1.41.10.8-1.0-1.01.0-1.00.8-1.3
Distance traveled after self-admin0.40.53.7-0.10.0-0.2-0.70.30.3-0.20.40.6-1.9
Extensor digitorum longus weight0.10.52.70.00.2-0.2-1.00.50.5-0.30.70.5-1.6
Bone: elastic displacement0.10.10.5-0.1-0.10.40.1-0.4-0.40.40.10.30.7
Bone: elastic work0.00.00.1-0.1-0.10.0-0.1-0.1-0.20.30.1-0.00.0
Bone: endosteal estimation0.10.10.4-0.3-0.50.10.6-0.3-0.30.4-0.5-0.30.3
Bone: endosteal perimeter0.20.51.3-0.4-0.70.31.1-0.5-0.50.6-1.0-0.51.0
Epididymis fat weight0.10.20.4-0.3-0.70.40.5-0.3-0.40.3-0.5-0.40.5
Delta time in closed arm before/after self-admin1.31.21.6-1.2-1.21.11.1-1.2-1.11.1-1.31.2-0.1
Delta time in open arm before/after self-admin2.32.33.11.81.7-1.4-1.41.61.6-1.61.5-1.40.9
Diff in mean of infusions in LGA sessions0.20.32.10.30.20.20.3-0.0-0.10.1-0.00.31.5
Delay discount exponential model param0.40.40.90.60.9-0.7-0.80.60.6-0.50.70.3-0.5
Extinction: sum of active levers before priming2.82.83.7-1.7-1.71.51.9-1.9-1.91.9-1.81.01.2
Active lever presses in extinction session 60.10.10.20.20.3-0.3-0.30.20.2-0.20.20.10.4
Bone: final force1.52.43.71.11.0-1.6-1.71.61.5-1.31.5-1.7-1.9
Bone: final moment1.01.63.30.80.7-1.3-1.31.21.2-1.01.2-1.6-1.8
Food consumed during 24 hour testing period6.57.810.03.22.9-3.0-2.83.03.0-3.12.8-2.80.1
Glucose0.10.20.40.40.6-0.5-0.50.20.1-0.30.40.3-0.5
Heart weight2.23.14.8-2.0-2.21.72.0-1.8-1.91.8-2.10.8-0.0
Delay discount hyperbolic model param0.40.40.90.70.9-0.7-0.80.60.6-0.50.70.3-0.5
Intermittent access intake day 1-15 change3.53.44.52.02.1-1.7-2.02.12.1-2.11.8-1.1-1.0
Intermittent access intake escalation5.45.36.72.52.6-2.2-2.52.62.6-2.62.3-1.5-1.1
Intermittent access intake escalation 23.13.14.32.02.1-1.7-1.72.02.0-1.91.6-1.2-0.6
Intermitt. access day 1 inactive lever presses0.20.20.3-0.3-0.50.40.6-0.4-0.40.4-0.50.10.4
Intermitt. access day 15 inactive lever presses0.80.91.6-0.5-0.51.11.0-0.8-0.80.8-0.91.31.2
Intermitt. access escalation Index0.50.41.00.60.6-0.6-0.40.60.6-0.60.4-1.00.8
Intermittent access day 1 total infusions3.13.64.7-2.1-2.02.02.0-2.2-2.22.1-1.91.60.2
Intermittent access day 15 total infusions0.00.00.2-0.00.10.0-0.0-0.0-0.0-0.00.00.4-0.2
Intermittent access terminal intake (last 3 days)0.20.20.4-0.3-0.30.60.6-0.3-0.40.4-0.50.60.3
Intermittent access total infusions0.20.20.3-0.5-0.40.40.6-0.5-0.50.5-0.40.40.0
Intermittent access day 1 locomotion0.70.81.4-1.1-1.20.90.8-0.9-0.90.9-0.80.6-0.3
Intermittent access day 15 total locomotion0.40.41.0-0.8-0.70.80.3-0.5-0.50.5-0.41.0-0.8
Intermittent access total locomotion0.60.61.6-1.0-0.90.80.4-0.6-0.60.6-0.50.8-1.3
Intermittent access standard deviation0.20.20.40.50.6-0.5-0.50.60.6-0.50.4-0.2-0.5
Left kidney weight0.20.62.80.2-0.0-0.3-0.70.70.5-0.40.8-1.0-1.7
Right kidney weight0.30.93.5-0.9-1.30.60.5-0.4-0.40.5-0.4-1.1-1.9
Cocaine induced anxiety1.31.53.8-0.7-0.71.01.6-1.1-1.11.1-1.50.32.0
Post-drug Anxiety0.70.82.2-0.5-0.50.61.1-0.8-0.80.8-1.00.61.5
Baseline Anxiety0.60.72.60.30.3-0.6-1.20.60.6-0.61.00.0-1.6
Tail length1.85.36.92.22.0-2.5-2.52.62.6-2.52.2-2.5-1.2
Length with tail0.10.52.10.2-0.1-0.5-0.50.50.5-0.50.4-1.4-1.3
Length without tail1.63.55.4-2.1-2.32.02.0-2.1-2.12.1-1.70.6-0.7
Times rat made contact with spout0.10.20.50.30.3-0.5-0.40.40.4-0.50.20.0-0.7
Lifetime Intake0.20.20.3-0.4-0.50.60.6-0.5-0.50.4-0.40.30.3
Liver weight, left0.10.20.60.00.1-0.10.3-0.6-0.40.1-0.1-0.60.8
Liver weight, right0.00.10.3-0.0-0.30.30.1-0.2-0.20.2-0.0-0.60.3
Locomotor activity0.40.61.3-0.9-1.00.50.5-1.1-1.00.9-0.60.3-0.7
Locomotor testing distance0.30.51.1-0.6-0.70.50.6-1.0-1.00.8-0.70.60.4
Locomotor testing rearing0.50.71.71.10.9-0.9-0.60.70.8-0.80.8-1.30.6
Locomotion in novel chamber0.60.82.1-1.0-1.20.90.7-0.7-0.70.7-0.7-0.2-1.5
Locomotion in novel chamber post-restriction0.10.10.20.20.1-0.3-0.40.20.4-0.40.4-0.3-0.4
Fecal boli incidents, locomotor time 10.90.91.41.21.1-0.8-1.00.90.9-0.91.1-1.00.3
Change in fecal boli incidents, locomotor task0.10.10.80.20.20.10.10.10.2-0.20.10.10.9
Time >=10cm from walls, locomotor time 10.40.42.1-0.1-0.2-0.2-0.50.30.3-0.30.4-0.8-1.4
Bouts of movement, locomotor time 11.01.11.71.31.2-1.0-0.91.01.0-1.01.2-0.41.0
Total resting periods, locomotor time 10.50.61.41.00.9-0.7-0.50.70.6-0.60.80.21.2
Rest time, locomotor task time 10.50.50.80.90.9-0.5-0.80.80.8-0.80.60.60.3
Distance moved, locomotor task time 10.80.91.3-0.9-0.90.91.1-1.1-1.11.1-0.80.21.2
Vertical activity count, locomotor time 10.40.41.30.60.4-0.5-0.70.60.6-0.60.8-1.1-0.4
Time >=10cm from walls, locomotor time 20.40.52.0-0.8-1.00.70.3-0.3-0.20.3-0.40.1-1.4
Bouts of movement, locomotor time 20.30.31.3-0.2-0.20.40.3-0.3-0.30.3-0.41.01.1
Total resting periods, locomotor time 20.30.32.00.20.20.10.1-0.1-0.10.0-0.20.81.4
Rest time, locomotor task time 20.80.94.91.01.0-0.1-0.30.30.3-0.40.41.42.2
Distance moved, locomotor task time 21.61.93.8-1.8-1.91.21.3-1.3-1.41.4-1.2-0.3-1.3
Vertical activity count, locomotor time 20.91.04.6-0.0-0.3-0.4-0.40.40.4-0.40.5-2.1-2.1
Light reinforcement 114.426.331.85.55.2-5.5-5.35.65.5-5.45.3-5.2-0.8
Light reinforcement 210.814.518.04.23.9-4.2-4.04.24.1-4.23.8-3.5-0.2
Bone: marrow area0.10.20.4-0.3-0.50.20.7-0.3-0.40.5-0.6-0.30.3
Bone: maximum diameter0.30.61.1-0.8-0.80.51.1-0.6-0.80.9-1.00.10.1
Bone: maximum force0.20.40.70.60.6-0.8-0.80.80.6-0.30.6-0.5-0.7
Bone: maximum moment0.10.20.40.30.3-0.6-0.50.50.4-0.10.4-0.5-0.6
Mean time between licks in bursts0.40.50.8-0.9-0.90.60.9-0.6-0.60.6-0.7-0.6-0.5
Mean num. licks in bursts0.30.32.0-0.4-0.20.40.2-0.3-0.40.2-0.41.4-0.2
Cd content in liver0.20.21.1-0.1-0.20.40.6-0.2-0.20.4-0.3-0.31.0
Co content in liver0.30.31.0-0.6-0.30.60.1-0.5-0.30.5-0.00.8-1.0
Cu content in liver0.10.10.3-0.4-0.50.30.2-0.0-0.10.3-0.2-0.3-0.3
Fe content in liver0.70.92.50.50.7-0.8-1.30.90.9-0.80.90.4-1.6
K content in liver0.30.31.3-0.7-0.80.40.1-0.4-0.30.6-0.2-0.2-1.2
Mg content in liver0.80.91.5-1.2-1.21.10.7-0.9-0.71.0-0.80.5-0.8
Mn content in liver1.11.32.2-1.1-1.11.51.0-1.0-1.01.4-1.01.40.6
Na content in liver0.20.21.4-0.2-0.6-0.2-0.20.00.1-0.10.1-0.5-1.2
Rb content in liver0.91.12.80.60.7-0.8-1.41.01.2-1.01.1-0.7-1.7
Se content in liver2.22.63.91.31.3-1.8-2.01.81.7-1.61.4-1.3-2.0
Sr content in liver0.10.10.6-0.0-0.1-0.1-0.20.20.2-0.20.2-0.7-0.8
Zn content in liver2.93.24.7-1.6-1.42.22.0-1.7-1.71.9-1.92.01.3
Bone: minimum diameter0.91.72.41.31.0-1.4-1.31.61.5-1.41.4-1.5-0.6
Time in familiar zone, hab. session 11.21.14.50.80.3-1.0-0.81.01.0-1.10.8-2.1-0.7
Time in novel zone, hab. session 11.21.26.4-0.7-0.31.00.5-0.9-0.91.0-0.72.50.3
Total zone transitions, hab. session 10.20.30.5-0.4-0.10.50.6-0.6-0.60.5-0.60.70.3
Total locomotion distance, hab. session 10.60.81.7-0.6-0.50.90.9-0.9-0.90.8-0.81.31.0
Locomotion velocity, hab. session 10.50.71.2-0.6-0.40.80.9-0.9-0.90.7-0.81.01.1
Time in familiar zone, hab. session 21.61.63.21.51.2-1.3-0.81.31.2-1.31.0-1.81.1
Time in novel zone, hab. session 23.33.38.0-2.0-1.52.11.4-1.8-1.81.9-1.62.8-0.3
Total zone transitions, hab. session 20.10.10.30.20.5-0.00.10.10.1-0.1-0.00.40.5
Total locomotion distance, hab. session 20.20.21.1-0.00.30.30.3-0.1-0.10.2-0.21.10.8
Locomotion velocity, hab. session 20.10.10.50.20.50.0-0.10.20.2-0.10.10.70.5
Novel to familiar place preference ratio1.21.32.0-1.1-1.41.21.1-1.2-1.31.3-1.01.10.3
Novelty place preference1.01.01.4-0.9-1.21.00.9-1.1-1.11.1-0.91.20.4
Time in novel zone, NPP test1.01.01.6-1.0-1.31.00.8-1.1-1.11.1-0.91.1-0.2
Total zone transitions, NPP test0.00.00.1-0.20.20.20.20.10.10.10.0-0.1-0.3
Total locomotion distance, NPP test0.10.10.4-0.5-0.20.50.3-0.2-0.20.5-0.30.6-0.3
Locomotion velocity, NPP test0.00.00.1-0.10.10.30.10.20.20.10.00.30.0
Intraocular pressure5.17.18.7-2.5-2.62.93.0-2.8-2.82.7-2.82.52.0
Delta distance traveled before/after self-admin1.11.21.61.01.2-1.2-1.31.21.1-1.11.2-0.6-0.7
Delta ambulatory time before/after self-admin2.02.23.11.41.6-1.8-1.61.61.5-1.41.6-1.3-0.8
Parametrial fat weight0.10.21.0-0.3-0.20.10.3-0.2-0.10.2-0.0-1.0-0.6
Pavlov. Cond. lever latency0.00.00.30.10.00.00.2-0.2-0.10.10.1-0.20.5
Pavlov. Cond. magazine entry latency0.10.20.6-0.4-0.20.30.1-0.4-0.50.4-0.20.7-0.5
Pavlov. Cond. change in total contacts0.91.01.60.71.0-1.2-1.11.11.0-1.30.7-0.4-1.1
Pavlov. Cond. index score0.10.20.3-0.5-0.40.30.2-0.4-0.40.3-0.40.4-0.5
Pavlov. Cond. latency score0.10.10.2-0.3-0.20.30.2-0.3-0.30.2-0.30.5-0.0
Pavlov. Cond. lever contacts0.10.10.7-0.3-0.3-0.0-0.10.10.0-0.1-0.30.0-0.8
Pavlov. Cond. magazine entry number0.20.32.00.50.30.00.10.20.3-0.20.20.01.4
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.3-0.50.40.3-0.3-0.20.2-0.3-0.1-0.0
Pavlov. Cond. lever-magazine prob. diff.0.20.30.4-0.7-0.50.50.3-0.5-0.60.5-0.60.6-0.5
Pavlov. Cond. response bias0.30.43.0-0.7-0.50.0-0.1-0.2-0.20.1-0.40.3-1.7
Pavlov. Cond. lever latency0.40.52.1-0.3-0.10.70.2-0.4-0.60.7-0.31.51.0
Pavlov. Cond. magazine entry latency0.10.10.8-0.00.1-0.30.10.10.2-0.20.0-0.9-0.6
Pavlov. Cond. change in total contacts0.20.32.2-0.1-0.0-0.3-0.20.10.4-0.40.2-0.8-1.5
Pavlov. Cond. index score0.20.31.6-0.2-0.2-0.30.0-0.00.2-0.40.1-1.0-1.3
Pavlov. Cond. latency score0.20.21.3-0.1-0.1-0.2-0.10.10.3-0.40.1-0.8-1.2
Pavlov. Cond. lever contacts0.81.13.70.70.4-1.0-0.70.71.0-1.20.8-1.9-1.2
Pavlov. Cond. magazine entry number0.10.10.80.40.10.0-0.20.20.1-0.00.20.30.9
Pavlov. Cond. intertrial magazine entries0.50.71.11.00.7-0.7-0.90.90.8-0.80.9-0.80.6
Pavlov. Cond. lever-magazine prob. diff.0.20.31.7-0.2-0.2-0.30.00.00.3-0.40.1-1.0-1.3
Pavlov. Cond. response bias0.40.62.70.1-0.1-0.6-0.20.20.5-0.70.2-1.6-1.5
Time in closed arm before self-admin3.23.64.41.71.7-2.0-2.12.02.0-2.02.0-2.0-1.3
Time in closed arm after self-admin0.70.71.40.50.8-1.2-1.10.80.8-0.80.8-0.6-1.1
Time in open arm before self-admin2.62.93.6-1.9-1.91.81.9-1.8-1.81.8-1.91.2-0.2
Time in open arm after self-admin0.60.71.2-0.8-0.91.10.9-0.8-0.80.8-0.90.60.2
Bone: periosteal estimation0.00.10.30.10.0-0.30.10.30.20.0-0.1-0.50.1
Bone: periosteal perimeter0.20.40.9-0.4-0.60.31.0-0.5-0.50.6-0.7-0.30.8
Bone: post-yield work0.10.20.80.20.0-0.50.60.1-0.10.0-0.6-0.10.9
Progressive ratio test 1 active lever presses1.71.82.8-1.6-1.71.51.1-1.3-1.31.2-1.21.0-1.2
Progressive ratio test 1 breakpoint1.21.21.9-1.3-1.41.30.9-1.1-1.11.0-1.00.9-1.2
Progressive ratio test 1 inactive lever presses0.20.20.7-0.5-0.60.50.3-0.4-0.40.3-0.40.1-0.8
Progressive ratio test 2 active lever presses0.50.61.3-0.8-0.61.00.5-0.7-0.70.7-0.61.1-0.7
Progressive ratio test 2 breakpoint0.60.71.5-0.9-0.71.10.7-0.8-0.80.8-0.71.2-0.5
Progressive ratio test 2 inactive lever presses2.42.73.7-1.6-1.71.91.9-1.7-1.71.7-1.81.60.6
Incentive Sensitization - Responses0.10.10.50.10.40.2-0.0-0.0-0.00.00.10.70.3
Incentive Sensitization - Breakpoint0.10.10.40.30.50.1-0.10.10.1-0.10.20.60.3
Sum of active levers in priming session hrs 5-60.20.21.60.50.5-0.3-0.00.20.2-0.20.2-0.31.3
Progressive ratio0.40.52.20.60.8-0.2-0.20.50.5-0.50.20.91.5
Food seeking constrained by brief footshock2.43.04.22.11.9-1.8-1.61.81.7-1.91.6-1.51.0
Seeking ratio, punishment vs. effort1.01.23.60.80.7-1.3-1.10.90.8-0.91.0-1.9-1.2
Retroperitoneal fat weight0.41.42.4-1.0-1.61.51.5-1.1-1.11.3-1.1-0.50.9
Reaction time number correct0.91.21.8-1.2-0.91.20.9-1.3-1.21.3-1.11.30.3
Reaction time mean minus median1.01.32.2-1.4-1.50.90.9-1.1-0.91.0-1.30.9-1.3
Reaction time mean minus median AUC1.01.32.0-1.4-1.41.11.0-1.2-1.01.1-1.31.0-0.9
Reaction time num false alarms4.25.77.7-2.6-2.52.62.7-2.5-2.82.8-2.71.10.3
Reaction time num false alarms AUC3.85.27.1-2.4-2.22.42.6-2.5-2.72.6-2.51.20.5
Reaction time trials correct on left0.91.21.8-1.2-0.91.20.9-1.3-1.21.3-1.11.30.3
Reaction time trials on left1.01.42.0-1.3-1.01.31.0-1.4-1.31.4-1.21.40.3
Reaction time mean2.12.94.7-2.2-2.11.91.6-1.5-1.51.6-1.71.5-1.3
Reaction time mean AUC2.23.04.8-2.2-2.11.81.7-1.6-1.61.7-1.81.5-1.2
Median of all reaction times1.92.64.2-2.1-1.91.81.6-1.4-1.51.5-1.61.4-1.1
Reaction time omissions2.02.74.2-2.0-2.01.71.7-1.8-1.71.7-1.60.7-0.9
Reaction time false alarm rate1.31.93.1-1.5-1.41.41.8-1.4-1.61.5-1.60.20.2
Reaction time premature initiation rate4.35.78.82.72.4-2.4-1.82.52.6-2.42.5-3.00.6
Reaction time premature initiations1.52.13.31.71.6-1.4-1.11.41.5-1.41.6-1.80.7
Std. dev. reaction times1.11.62.7-1.6-1.61.11.2-1.2-1.01.1-1.40.7-1.3
Reaction time trials completed1.01.42.0-1.3-1.01.31.0-1.4-1.31.4-1.21.40.3
Reaction time trials AUC1.01.41.9-1.3-1.11.31.0-1.3-1.31.4-1.21.40.3
Run reversals in cocaine runway, females1.11.01.5-1.2-1.21.10.8-1.2-1.01.1-1.10.8-0.5
Run reversals in cocaine runway, males0.20.21.3-0.30.20.2-0.1-0.5-0.40.5-0.11.10.1
Latency to leave start box in cocaine runway0.30.31.6-0.2-0.40.60.5-0.3-0.30.2-0.30.31.3
Latency to leave start box in cocaine runway, F0.80.93.0-0.8-0.70.90.6-0.8-0.80.8-0.91.70.7
Latency to leave start box in cocaine runway, M2.32.27.01.61.1-1.1-0.81.61.4-1.51.3-2.61.2
Std. dev. time between licks in bursts0.20.30.60.50.6-0.2-0.60.60.6-0.50.8-0.4-0.3
Total sessions with >9 infusions0.60.71.2-0.9-1.10.90.9-0.9-0.90.8-0.80.20.1
Short access day 1 total inactive lever presses0.20.30.40.50.5-0.3-0.50.60.6-0.50.6-0.5-0.4
Short access day 10 total inactive lever presses0.60.71.40.90.9-0.9-0.50.80.8-0.70.7-1.20.4
Short access day 1 total infusions1.81.92.8-1.5-1.71.71.6-1.4-1.41.4-1.40.80.2
Short access day 10 total infusions0.20.20.5-0.3-0.20.70.5-0.5-0.50.4-0.20.70.6
Short access total infusions0.10.10.3-0.3-0.40.50.3-0.3-0.30.2-0.20.2-0.1
Short access day 1 locomotion2.12.23.2-1.5-1.71.81.6-1.5-1.51.5-1.51.40.5
Short access day 10 total locomotion0.30.30.6-0.7-0.80.50.7-0.6-0.60.5-0.50.1-0.1
Short access total locomotion1.01.11.6-1.1-1.21.31.1-1.0-1.01.0-1.01.10.3
One hour access (0.3 mA shock)0.30.32.10.20.10.30.5-0.2-0.20.1-0.20.61.4
Compulsive drug intake1.01.01.71.31.2-0.9-0.91.01.0-1.01.00.00.9
One hour access (shock baseline)1.01.11.7-0.8-0.91.11.3-1.1-1.11.1-1.01.01.1
Social response proportion0.10.10.7-0.4-0.30.2-0.2-0.1-0.00.30.1-0.1-0.9
Social responses0.20.20.6-0.2-0.30.40.6-0.4-0.30.5-0.3-0.60.8
Social time0.81.11.91.11.4-0.8-1.41.11.1-1.11.40.10.2
Soleus weight0.10.20.7-0.00.00.30.5-0.4-0.60.5-0.30.20.9
Bone: stiffness0.30.41.80.30.3-0.8-0.60.60.5-0.30.3-0.6-1.4
Tibialis anterior weight0.62.12.8-1.7-1.61.61.2-1.4-1.51.7-1.41.5-0.6
Time to tail flick, vehicle, before self-admin0.80.86.60.70.7-0.20.10.10.2-0.20.10.72.6
Time to tail flick, vehicle, after self-admin0.80.81.61.21.1-0.6-0.60.90.9-0.90.9-0.31.3
Time to tail flick, test, before self-admin0.60.61.2-0.6-0.81.10.8-0.7-0.70.6-0.80.70.7
Time to tail flick, test, after self-admin0.50.51.10.70.8-1.1-0.60.60.7-0.70.6-0.70.3
Delta time to tail flick, vehicle, before/after SA0.40.41.00.60.5-0.4-0.50.70.6-0.60.7-1.0-0.4
Delta time to tail flick, test, before/after SA0.90.82.10.40.7-1.3-1.00.70.8-0.70.8-0.8-1.4
Tibia length0.41.16.5-0.9-1.3-0.30.2-0.4-0.50.0-0.6-1.0-2.5
Ambulatory time before self-admin1.31.42.2-1.5-1.51.11.0-1.2-1.21.2-1.20.5-1.0
Ambulatory time after self-admin0.91.02.80.60.8-1.0-1.31.00.9-0.81.0-0.3-1.7
Bone: tissue strength0.40.31.10.3-0.1-0.3-0.60.50.4-0.20.8-1.1-0.8
Total heroin consumption0.00.10.2-0.2-0.20.10.2-0.1-0.10.1-0.2-0.3-0.4
Bone: trabecular number1.42.24.01.82.0-1.4-1.71.41.4-1.21.60.71.1
Bone: trabecular spacing1.01.32.5-1.4-1.61.51.2-1.0-1.01.1-1.2-0.1-0.5
Bone: trabecular thickness2.73.25.11.82.0-1.9-2.32.01.8-1.92.1-0.3-0.5
Bone: trabecular tissue density0.30.40.8-0.8-0.90.60.5-0.3-0.70.3-0.80.1-0.4
Water consumed over 24 hours2.93.54.42.12.1-2.0-2.02.12.0-2.01.9-1.4-0.6
Number of responses in last shaping day5.05.27.4-2.2-2.32.72.5-2.2-2.22.3-2.42.31.0