Hub : Genes

Nfix

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Nfix 0.03 0.02 9.7e-03 0.01 0.01 0 0.01 1.5e-02 1.6e-02 7.5e-02 2.4e-02
2 Brain alternative TSS XM_063278302.1 0.07 0.04 2.6e-05 0.03 0.06 0.05 0.04 1.1e-03 4.2e-06 1.1e-05 4.3e-05
3 Liver alternative TSS XM_063278302.1 0.18 0.08 0.0e+00 0.18 0.17 0.18 0.18 5.0e-20 5.2e-19 7.4e-20 8.8e-20
4 pVTA gene expression Nfix 0.1 0.06 8.5e-05 0.04 0.04 0.04 0.04 4.6e-04 2.9e-04 2.2e-04 5.7e-04
5 Liver isoform ratio XM_063278302.1 0.1 0.05 2.7e-08 0.05 0.05 0.05 0.06 2.3e-06 1.1e-06 1.5e-06 3.8e-07
6 OFC gene expression Nfix 0.19 0.1 6.9e-03 0.06 0.06 0.05 0.04 1.2e-02 1.6e-02 2.4e-02 4.9e-02
7 Liver alternative TSS XM_063278302.1 0.19 0.08 0.0e+00 0.19 0.2 0.2 0.2 4.7e-21 3.0e-21 8.9e-22 7.1e-22
8 IL mRNA stability Nfix 0.21 0.11 2.4e-03 0.1 0.09 0.04 0.1 2.3e-03 3.1e-03 3.8e-02 1.9e-03
9 Brain gene expression Nfix 0.3 0.11 0.0e+00 0.15 0.2 0.2 0.21 7.4e-14 6.0e-18 1.3e-18 2.0e-19
10 NAcc gene expression Nfix 0.04 0.02 1.6e-03 0.01 0 0 0.01 6.3e-03 1.5e-01 6.5e-02 3.3e-02
11 Brain mRNA stability Nfix 0.09 0.05 1.7e-04 0.01 0.03 0.03 0.03 7.0e-02 3.8e-04 7.3e-04 1.7e-03
12 OFC alternative TSS XM_063278306.1 0.27 0.14 7.7e-03 0.03 0.06 0.08 0.06 5.9e-02 1.3e-02 5.4e-03 1.4e-02
13 Liver alternative TSS NM_030866.1 0.04 0.02 1.8e-04 0.03 0.02 0.02 0.02 4.4e-04 1.7e-03 1.1e-03 2.3e-03
14 Liver alternative TSS NM_030866.1 0.04 0.02 1.5e-04 0.03 0.02 0.02 0.02 4.6e-04 1.8e-03 1.0e-03 2.0e-03
15 BLA isoform ratio XM_063278303.1 0.06 0.04 8.1e-03 -0 -0 -0 -0 3.6e-01 5.4e-01 6.6e-01 4.7e-01
16 Adipose alternative polyA NM_030866.1 0.03 0.02 2.6e-03 0.01 0.01 0.01 0.01 7.5e-03 4.0e-02 2.4e-02 2.6e-02
17 Adipose alternative polyA XM_063278302.1 0.04 0.02 1.6e-03 0.01 0.01 0.01 0.01 6.9e-03 3.3e-02 2.1e-02 3.1e-02
18 IC gene expression Nfix 0.21 0.11 2.9e-06 0.14 0.11 0.1 0.11 1.8e-06 2.1e-05 7.9e-05 2.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density3.35.710.92.7-2.3-2.61.9-2.63.1-2.62.43.31.53.30.02.92.9-2.3-1.11.11.6
Area under the delay curve0.20.31.0-0.2-0.10.3-0.50.30.50.1-0.40.7-0.50.6-1.00.70.7-0.4-0.60.60.2
BMI with tail1.55.311.3-2.61.12.7-2.13.1-2.62.6-3.4-2.7-2.9-2.8-0.6-1.8-1.82.3-1.21.2-1.8
BMI without tail0.10.41.6-0.2-0.20.4-0.40.70.10.2-0.9-0.2-0.7-0.5-0.90.50.50.0-1.21.20.4
Body weight0.20.74.4-0.4-0.10.70.50.5-1.00.4-0.4-1.80.3-2.11.0-0.8-0.80.9-0.20.2-0.0
Weight adjusted by age0.20.40.7-0.80.80.8-0.80.7-0.70.8-0.6-0.3-0.5-0.2-0.5-0.6-0.60.40.4-0.4-0.5
Bone surface3.15.68.82.5-0.9-2.61.8-2.82.9-2.72.92.92.52.6-0.62.52.5-3.00.7-0.72.7
Bone volume3.35.89.82.5-1.2-2.41.9-2.82.9-2.63.13.12.62.9-0.32.62.6-3.00.6-0.62.6
Breakpoint value in progressive ratio session0.91.15.70.1-1.0-0.11.0-0.0-0.80.2-0.1-1.40.0-0.82.4-1.4-1.41.7-0.70.7-1.1
Number of licking bursts0.50.84.40.4-1.6-0.40.8-0.00.6-0.5-0.5-0.1-0.0-0.40.50.80.80.3-2.12.1-0.1
Context. condit. distance diff. score1.51.85.1-1.70.81.6-0.91.7-1.61.5-1.7-2.0-1.1-2.3-0.1-1.2-1.21.4-0.20.2-0.9
Locomotion velocity, session 11.11.12.41.1-0.9-1.01.2-1.31.3-1.21.51.11.31.10.50.90.9-1.00.0-0.01.2
Locomotion distance, session 10.30.41.70.3-1.30.01.2-0.10.3-0.20.1-0.50.5-0.61.20.10.10.4-1.01.00.3
Locomotion velocity, session 20.70.81.81.0-1.4-1.10.8-0.81.1-1.00.40.80.30.60.31.01.0-0.5-1.21.20.6
Locomotion distance, session 20.60.82.3-0.4-1.00.70.80.7-0.60.4-0.7-1.4-0.0-1.51.4-0.7-0.71.1-1.11.1-0.4
Locomotion velocity, session 30.10.10.4-0.20.60.4-0.50.20.10.10.00.30.00.1-0.70.30.3-0.40.5-0.50.4
Locomotion distance, session 31.11.24.00.6-0.2-0.50.4-0.51.5-1.10.31.00.60.1-1.51.91.9-1.6-0.50.52.0
Stereotopy head waving bouts, day 30.80.94.1-0.71.80.8-1.50.5-0.30.6-0.30.3-0.40.1-2.00.10.1-0.71.3-1.30.6
Stereotopy head waving duration, day 30.30.41.5-0.61.00.6-1.20.7-0.40.6-0.7-0.1-0.8-0.1-1.2-0.1-0.10.00.3-0.3-0.0
Locomotion velocity, session 70.20.21.5-0.30.20.3-0.10.5-0.20.1-0.8-0.6-0.3-1.2-0.40.20.20.1-0.40.40.5
Locomotion distance, session 70.20.31.10.5-0.9-0.41.0-0.30.3-0.50.0-0.20.3-0.50.90.30.30.1-0.70.70.3
Stereotopy head waving bouts, day 70.60.73.50.10.4-0.4-0.5-0.20.8-0.5-0.00.90.10.3-1.91.31.3-1.2-0.10.11.2
Stereotopy head waving duration, day 70.91.12.50.7-0.2-1.0-0.0-0.81.3-1.00.51.40.40.9-1.51.61.6-1.4-0.40.41.3
Locomotion velocity, session 80.30.41.7-0.3-0.20.50.90.1-0.40.10.3-1.00.7-1.21.3-0.6-0.60.50.4-0.40.1
Locomotion distance, session 81.01.45.2-1.0-0.61.10.41.2-1.00.8-1.4-1.9-0.5-2.31.1-0.8-0.81.5-1.21.2-0.6
Degree of sensitization distance0.80.84.20.0-0.5-0.00.60.1-1.00.3-0.1-1.1-0.1-0.62.0-1.3-1.31.30.0-0.0-1.4
Degree of sensitization stereotypy0.40.41.90.10.1-0.5-0.3-0.20.6-0.5-0.20.6-0.10.1-1.41.11.1-0.8-0.40.40.8
Conditioned locomotion0.10.10.40.2-0.2-0.10.5-0.30.1-0.20.5-0.10.6-0.20.6-0.0-0.0-0.10.4-0.40.3
Cocaine response after cond. corrected0.70.92.4-0.4-0.10.60.30.6-1.10.6-0.6-1.6-0.3-1.31.4-1.4-1.41.5-0.10.1-0.7
Cocaine response after cond. not corrected0.80.92.5-0.4-0.40.70.40.7-1.00.6-0.6-1.4-0.4-1.11.6-1.3-1.31.5-0.50.5-1.0
Cocaine response before conditioning0.40.51.30.5-0.7-0.40.3-0.40.9-0.50.41.00.10.8-0.21.11.1-0.9-0.70.70.4
Saline control response1.92.68.11.8-2.9-1.72.6-1.31.2-1.70.7-0.11.1-0.22.50.70.70.4-2.22.20.2
Bone: connectivity density5.68.815.73.5-2.5-3.52.2-3.14.0-3.52.63.91.93.6-0.63.73.7-3.2-1.21.22.4
Bone: cortical apparent density0.60.82.90.0-0.1-0.1-0.90.70.3-0.0-1.50.3-1.5-0.1-1.71.01.0-0.1-1.41.4-0.1
Bone: cortical area0.20.31.2-0.1-0.5-0.01.0-0.2-0.1-0.20.4-0.81.0-1.11.0-0.3-0.30.20.2-0.20.5
Bone: cortical porosity1.31.43.1-1.31.01.5-0.51.0-1.41.2-0.4-1.6-0.1-1.30.7-1.8-1.81.21.1-1.1-0.5
Bone: cortical porosity1.01.12.2-1.11.11.3-0.30.7-1.20.9-0.1-1.50.4-1.50.5-1.5-1.50.81.4-1.40.2
Bone: cortical thickness1.11.85.9-1.60.41.6-0.51.6-1.71.4-1.6-2.2-0.8-2.40.5-1.3-1.31.5-0.20.2-0.8
Bone: cortical thickness2.83.311.1-0.5-2.30.60.31.3-0.80.9-2.1-1.2-2.2-0.81.9-0.5-0.52.4-3.33.3-2.6
Bone: cortical tissue density0.60.83.20.1-0.0-0.1-0.80.60.4-0.1-1.40.4-1.3-0.1-1.81.11.1-0.3-1.31.30.1
Condit. Reinf. active minus inactive responses1.51.66.9-1.81.11.7-1.01.6-0.71.0-1.6-1.3-0.4-2.6-1.90.30.3-0.2-0.50.51.4
Condit. Reinf. active-inactive response ratio1.61.77.8-1.60.51.7-0.61.7-1.21.2-1.8-2.0-0.7-2.8-0.5-0.7-0.70.9-0.80.80.3
Condit. Reinf. active responses0.70.83.4-1.10.70.9-0.70.80.00.4-0.8-0.3-0.1-1.4-1.81.01.0-0.9-0.30.31.5
Condit. Reinf. inactive responses2.22.65.11.5-0.7-1.71.0-1.82.0-1.71.72.21.51.8-0.52.22.2-2.30.4-0.41.6
Incentive salience index mean0.91.15.5-0.80.60.7-0.40.40.60.0-0.10.20.7-1.0-2.01.41.4-1.6-0.10.12.4
Condit. Reinf. lever presses1.52.16.90.30.3-0.30.1-0.91.6-0.81.41.71.60.9-1.72.02.0-2.60.5-0.52.6
Condit. Reinf. active minus inactive responses0.30.31.30.30.4-0.20.5-0.40.3-0.40.7-0.01.1-0.30.00.10.1-0.60.9-0.91.1
Condit. Reinf. active-inactive response ratio0.30.31.2-0.40.70.4-0.20.2-0.60.50.1-0.50.3-0.40.3-0.7-0.70.21.1-1.10.0
Condit. Reinf. active responses0.10.20.70.4-0.2-0.30.7-0.40.2-0.40.5-0.10.8-0.20.60.00.0-0.10.1-0.10.5
Condit. Reinf. inactive responses0.20.31.00.1-0.6-0.10.40.0-0.20.0-0.1-0.4-0.2-0.21.0-0.4-0.40.8-0.80.8-0.8
Condit. Reinf. lever presses0.00.00.1-0.00.30.2-0.40.20.00.1-0.10.1-0.20.2-0.3-0.0-0.0-0.0-0.00.0-0.1
Condit. Reinf. lever reinforcers received0.10.10.40.3-0.1-0.30.4-0.40.2-0.40.40.00.60.00.40.00.0-0.10.1-0.10.3
Conditioned reinforcement - actives0.00.10.3-0.20.10.30.10.0-0.10.20.2-0.10.2-0.00.3-0.2-0.20.10.6-0.60.1
Conditioned reinforcement - inactives0.10.21.1-0.20.70.2-0.30.1-0.20.2-0.0-0.2-0.0-0.1-0.2-0.3-0.30.11.0-1.0-0.0
Conditioned locomotion0.10.10.6-0.10.40.1-0.30.10.10.1-0.10.1-0.1-0.0-0.50.10.1-0.20.8-0.80.1
Patch foraging indifference point 0 sec0.30.62.2-0.61.00.50.20.0-0.20.00.3-0.80.9-1.5-0.4-0.0-0.0-0.51.2-1.21.5
Patch foraging indifference point AUC1.21.83.92.0-1.6-1.71.6-1.71.4-1.51.51.41.31.71.20.90.9-0.6-0.60.60.5
Delay disc. indifference point, 0s delay1.31.53.31.2-0.6-1.20.7-1.31.6-1.21.51.71.21.8-0.31.21.2-1.30.2-0.21.5
Delay disc. indifference point, 16s delay0.80.91.8-0.90.01.0-0.71.1-0.91.1-1.2-0.8-1.4-0.40.2-1.0-1.01.3-0.70.7-1.3
Delay disc. indifference point, 2s delay0.50.61.8-1.10.71.2-1.31.1-0.31.0-0.90.2-1.00.2-1.3-0.0-0.00.0-0.10.1-0.2
Delay disc. indifference point, 24s delay0.30.31.8-0.50.70.5-0.40.5-0.70.3-0.6-1.0-0.3-1.3-0.3-0.2-0.20.20.2-0.2-0.3
Delay disc. indifference point, 4s delay1.41.44.50.5-0.5-0.5-0.2-0.51.7-0.60.52.10.12.0-1.51.71.7-1.6-0.50.51.1
Delay disc. indifference point, 8s delay0.30.41.1-0.2-0.10.1-0.50.40.50.0-0.60.6-0.70.2-1.11.01.0-0.5-0.80.80.1
Indifference point function ln k1.01.84.3-1.92.11.7-1.81.6-1.11.4-1.4-1.0-1.0-1.6-2.1-0.4-0.4-0.00.9-0.90.6
Indifference point function log k1.01.84.3-1.92.11.7-1.81.6-1.11.4-1.4-1.0-1.0-1.6-2.1-0.4-0.4-0.00.9-0.90.6
Patch foraging total patch changes 0 sec0.40.73.0-1.01.20.9-0.10.5-0.60.5-0.0-1.10.6-1.7-0.4-0.4-0.4-0.11.2-1.21.1
Patch foraging total patch changes 12 sec0.91.23.20.9-1.4-0.91.8-1.01.1-1.21.00.11.6-0.60.81.11.1-0.7-0.90.91.4
Patch foraging total patch changes 18 sec1.82.86.11.9-2.0-1.82.5-2.01.9-2.02.01.12.10.91.31.51.5-1.2-0.60.61.8
Patch foraging total patch changes 24 sec1.22.03.81.7-0.8-1.81.7-1.81.5-1.81.61.01.90.40.31.51.5-1.50.2-0.21.8
Patch foraging total patch changes 6 sec0.40.50.90.9-1.0-0.61.0-0.70.9-0.80.70.60.80.50.60.70.7-0.5-0.60.60.8
Patch foraging time to switch 0 sec0.10.10.6-0.1-0.8-0.10.4-0.10.0-0.0-0.0-0.30.0-0.20.5-0.1-0.10.4-0.70.7-0.5
Patch foraging water rate 0 sec0.10.20.80.10.50.10.1-0.1-0.40.10.3-0.20.3-0.20.4-0.4-0.40.00.9-0.90.2
Patch foraging water rate 12 sec0.30.73.9-0.40.70.4-1.20.60.30.3-0.70.9-1.00.6-2.00.90.9-0.8-0.20.20.4
Patch foraging water rate 18 sec1.21.86.30.51.0-0.5-0.6-0.51.4-0.80.41.70.31.0-2.51.81.8-2.30.8-0.81.9
Patch foraging water rate 24 sec0.50.64.0-0.11.1-0.0-1.00.20.5-0.2-0.40.6-0.3-0.1-2.01.01.0-1.20.4-0.41.0
Patch foraging water rate 6 sec2.53.66.12.5-2.1-2.22.2-2.22.3-2.32.01.91.81.80.91.81.8-1.5-0.90.91.6
Seeking ratio, delayed vs. immediate footshock1.21.54.1-1.40.21.4-1.61.6-0.81.4-1.8-0.5-2.0-0.5-1.2-0.4-0.40.8-1.51.5-0.8
Distance traveled before self-admin0.81.12.4-1.31.51.3-1.31.2-1.21.3-0.9-0.6-0.9-0.5-0.7-0.9-0.90.61.0-1.0-0.4
Distance traveled after self-admin0.70.91.9-1.21.21.1-1.41.2-1.21.2-1.1-0.4-1.2-0.1-0.7-0.8-0.80.60.5-0.5-1.0
Extensor digitorum longus weight0.41.53.9-0.90.11.20.10.9-1.61.1-0.7-2.0-0.2-1.71.7-1.8-1.81.60.1-0.1-1.1
Bone: elastic displacement0.50.61.6-1.01.20.9-0.70.7-0.60.7-0.5-0.70.0-1.1-0.9-0.4-0.4-0.10.9-0.90.6
Bone: elastic work1.62.14.1-2.01.41.9-1.21.7-1.81.7-1.4-1.9-0.7-2.0-0.2-1.6-1.61.20.8-0.8-0.5
Bone: endosteal estimation0.30.63.10.5-1.3-0.51.5-0.70.3-0.60.8-0.21.00.01.8-0.2-0.20.4-0.50.5-0.0
Bone: endosteal perimeter0.61.35.60.7-0.8-0.72.0-1.20.7-1.21.6-0.22.4-0.61.30.30.3-0.70.6-0.61.6
Epididymis fat weight0.10.31.7-0.10.20.20.4-0.0-0.4-0.10.3-0.90.8-1.30.5-0.2-0.20.00.5-0.50.4
Delta time in closed arm before/after self-admin0.30.30.9-0.70.40.6-0.80.8-0.30.6-0.9-0.2-0.8-0.4-0.90.00.00.0-0.40.4-0.0
Delta time in open arm before/after self-admin2.01.96.51.8-1.7-1.72.5-1.80.6-1.51.8-0.12.00.12.5-0.1-0.10.2-0.00.00.3
Diff in mean of infusions in LGA sessions0.30.31.10.6-1.0-0.60.8-0.60.6-0.50.50.20.40.30.70.20.20.0-0.80.80.5
Delay discount exponential model param0.30.41.30.30.1-0.30.6-0.4-0.5-0.10.5-0.70.6-0.51.2-0.9-0.90.50.8-0.8-0.3
Extinction: sum of active levers before priming1.21.43.8-1.40.91.4-1.71.6-0.61.2-1.8-0.2-1.7-0.5-2.00.00.00.0-0.80.8-0.6
Active lever presses in extinction session 60.70.73.9-0.71.40.7-1.20.60.00.5-0.40.5-0.40.2-2.00.60.6-0.90.8-0.80.5
Bone: final force0.20.32.2-0.0-0.4-0.10.8-0.3-0.3-0.00.5-0.60.7-0.41.5-0.6-0.60.40.4-0.4-0.3
Bone: final moment0.20.31.8-0.3-0.40.10.7-0.1-0.40.20.3-0.70.6-0.61.3-0.7-0.70.50.3-0.3-0.3
Food consumed during 24 hour testing period4.15.713.82.8-3.7-2.73.2-2.62.7-2.62.31.92.02.02.42.02.0-1.0-2.32.30.7
Glucose0.40.72.10.20.6-0.10.4-0.3-0.7-0.10.5-0.90.7-0.71.1-1.2-1.20.51.5-1.5-0.3
Heart weight1.01.64.9-0.6-0.30.7-1.31.4-0.10.6-2.00.2-2.2-0.0-1.70.70.70.4-2.22.2-0.9
Delay discount hyperbolic model param0.50.51.70.20.3-0.20.6-0.4-0.7-0.00.5-0.90.7-0.61.3-1.1-1.10.61.0-1.0-0.3
Intermittent access intake day 1-15 change1.22.43.51.8-1.5-1.71.7-1.81.9-1.91.71.51.71.20.21.61.6-1.5-0.90.91.6
Intermittent access intake escalation0.71.52.21.3-1.3-1.31.3-1.31.5-1.41.31.21.30.90.11.31.3-1.2-1.11.11.3
Intermittent access intake escalation 21.51.72.71.6-1.3-1.51.4-1.51.6-1.71.41.31.41.00.11.41.4-1.3-0.90.91.1
Intermitt. access day 1 inactive lever presses0.31.24.10.41.2-0.6-0.0-0.80.8-0.71.00.91.00.6-1.10.80.8-1.32.0-2.01.7
Intermitt. access day 15 inactive lever presses0.51.02.2-1.11.11.1-0.80.9-1.11.2-0.7-0.9-0.7-0.70.2-1.1-1.10.91.5-1.5-0.7
Intermitt. access escalation Index0.20.31.9-0.30.40.2-0.80.40.30.2-0.70.3-0.70.0-1.40.50.5-0.4-0.60.60.3
Intermittent access day 1 total infusions1.52.54.0-1.91.51.9-1.71.8-1.92.0-1.5-1.5-1.5-1.1-0.2-1.7-1.71.51.1-1.1-1.5
Intermittent access day 15 total infusions0.30.51.0-1.00.81.0-0.90.9-0.71.0-0.8-0.5-0.7-0.4-0.5-0.6-0.60.60.2-0.2-0.4
Intermittent access terminal intake (last 3 days)0.50.71.4-1.01.21.0-0.90.8-0.91.0-0.6-0.6-0.6-0.5-0.3-0.8-0.80.61.1-1.1-0.7
Intermittent access total infusions1.01.21.8-1.31.21.3-1.01.1-1.31.3-0.9-1.0-0.8-0.7-0.0-1.3-1.31.11.2-1.2-1.1
Intermittent access day 1 locomotion1.11.42.6-1.51.31.4-1.61.5-1.11.5-1.4-0.9-1.4-0.8-0.9-1.0-1.00.90.9-0.9-0.8
Intermittent access day 15 total locomotion0.81.42.3-1.20.81.2-0.91.2-1.51.4-1.1-1.3-1.1-0.90.4-1.5-1.51.40.6-0.6-1.5
Intermittent access total locomotion1.82.13.5-1.50.91.5-1.11.6-1.81.7-1.5-1.6-1.5-1.10.4-1.9-1.91.80.7-0.7-1.7
Intermittent access standard deviation0.30.61.00.8-0.2-0.70.7-0.91.0-0.91.00.81.00.6-0.30.80.8-0.90.4-0.40.9
Left kidney weight0.73.17.12.1-2.2-2.12.7-2.01.8-2.21.60.42.2-0.21.31.61.6-1.2-1.41.41.7
Right kidney weight0.52.37.81.7-2.0-1.52.8-1.50.9-1.81.3-0.72.2-1.42.10.70.7-0.3-1.11.11.4
Cocaine induced anxiety0.40.51.8-0.51.30.6-0.90.4-0.10.3-0.30.4-0.30.0-1.40.50.5-0.71.1-1.10.3
Post-drug Anxiety0.20.20.5-0.70.60.6-0.70.6-0.50.6-0.7-0.2-0.7-0.3-0.6-0.2-0.20.20.0-0.0-0.0
Baseline Anxiety0.60.72.70.1-1.4-0.30.6-0.0-0.30.0-0.3-0.7-0.3-0.31.3-0.8-0.81.2-1.71.7-0.3
Tail length2.28.515.63.5-2.0-3.23.0-3.73.4-3.53.93.03.72.70.72.82.8-3.00.5-0.53.0
Length with tail0.73.09.12.0-1.0-1.82.4-2.31.3-2.02.80.83.00.61.60.80.8-1.21.2-1.21.6
Length without tail0.41.23.4-0.60.20.50.50.3-1.40.60.0-1.90.5-1.71.8-1.7-1.71.30.8-0.8-0.8
Times rat made contact with spout0.30.31.4-0.0-0.60.0-0.10.10.40.0-0.30.6-0.50.6-0.40.60.6-0.1-1.21.2-0.1
Lifetime Intake0.81.02.1-1.01.21.1-0.80.9-1.21.1-0.6-0.8-0.6-0.6-0.0-1.1-1.10.81.5-1.5-0.8
Liver weight, left0.60.92.80.80.2-0.81.2-1.20.4-0.91.40.11.70.00.6-0.1-0.1-0.61.5-1.51.1
Liver weight, right0.71.34.31.20.1-0.91.5-1.30.7-1.31.70.22.1-0.30.50.50.5-1.21.2-1.21.6
Locomotor activity0.60.92.4-0.7-1.00.80.20.8-0.90.9-0.6-1.0-0.7-0.51.5-1.1-1.11.6-1.01.0-1.1
Locomotor testing distance0.50.82.1-0.8-0.80.90.10.8-0.91.0-0.6-0.8-0.7-0.21.4-1.1-1.11.4-0.70.7-1.2
Locomotor testing rearing0.91.87.41.1-2.7-1.11.8-0.71.0-1.00.20.30.20.31.60.70.70.4-2.52.5-0.1
Locomotion in novel chamber0.81.13.8-0.5-1.30.40.10.6-0.50.6-0.9-1.0-1.0-0.61.2-0.7-0.71.4-2.02.0-1.1
Locomotion in novel chamber post-restriction0.40.71.10.90.2-0.80.5-0.90.8-0.90.90.91.10.8-0.20.60.6-1.01.0-1.00.7
Fecal boli incidents, locomotor time 11.01.55.61.1-0.1-1.11.6-1.60.6-1.32.00.12.4-0.20.70.40.4-1.01.3-1.31.6
Change in fecal boli incidents, locomotor task1.71.74.80.9-0.7-0.9-0.1-0.51.8-1.00.12.2-0.21.8-1.52.02.0-1.5-1.11.10.7
Time >=10cm from walls, locomotor time 10.30.41.20.4-0.8-0.3-0.0-0.00.6-0.2-0.31.0-0.61.1-0.10.50.50.1-1.01.0-0.3
Bouts of movement, locomotor time 10.30.31.2-0.60.70.6-0.90.4-0.10.5-0.10.8-0.20.5-1.10.30.3-0.50.5-0.50.1
Total resting periods, locomotor time 10.50.62.3-1.01.11.0-1.30.8-0.30.8-0.40.6-0.40.3-1.50.30.3-0.60.5-0.50.2
Rest time, locomotor task time 10.60.82.0-1.31.31.4-1.01.0-1.01.0-0.4-0.8-0.1-1.1-0.8-0.3-0.30.00.9-0.90.4
Distance moved, locomotor task time 10.30.51.70.4-0.8-0.30.3-0.0-0.1-0.1-0.5-0.3-0.70.31.0-0.7-0.71.1-0.90.9-1.3
Vertical activity count, locomotor time 11.22.86.52.5-2.5-2.52.4-2.01.5-2.01.21.01.01.42.40.40.40.3-1.21.2-0.5
Time >=10cm from walls, locomotor time 20.40.71.4-0.60.90.6-0.80.5-0.90.9-0.3-0.1-0.60.60.3-1.2-1.20.91.0-1.0-1.1
Bouts of movement, locomotor time 20.40.61.8-0.50.10.5-1.10.80.20.5-1.01.1-1.30.8-1.20.50.5-0.3-0.80.8-0.4
Total resting periods, locomotor time 20.20.41.2-0.2-0.10.2-0.80.50.30.3-0.81.1-1.00.8-0.80.50.5-0.3-0.80.8-0.3
Rest time, locomotor task time 20.10.10.30.1-0.5-0.20.4-0.30.3-0.20.40.30.40.30.20.50.5-0.2-0.30.30.3
Distance moved, locomotor task time 21.51.83.6-1.21.11.4-1.21.4-1.71.5-1.3-1.5-1.5-0.80.4-1.9-1.91.70.4-0.4-1.6
Vertical activity count, locomotor time 20.71.04.81.4-1.5-1.21.6-1.00.3-0.90.6-0.10.60.12.2-0.2-0.20.9-0.60.6-0.6
Light reinforcement 15.814.131.25.2-4.6-5.15.6-4.93.8-5.04.32.14.51.73.62.72.7-2.0-1.51.52.1
Light reinforcement 25.48.318.13.9-3.1-4.14.3-4.12.6-3.73.81.63.81.73.31.41.4-1.5-0.10.11.4
Bone: marrow area0.30.63.30.5-1.4-0.51.5-0.60.3-0.60.8-0.20.90.01.8-0.2-0.20.4-0.50.5-0.1
Bone: maximum diameter0.30.52.1-0.50.40.40.6-0.0-0.2-0.10.4-0.91.3-1.40.2-0.3-0.3-0.20.9-0.91.2
Bone: maximum force0.20.41.7-0.10.00.00.6-0.2-0.50.10.5-0.80.7-0.61.3-0.9-0.90.50.8-0.8-0.2
Bone: maximum moment0.20.41.4-0.30.00.20.5-0.0-0.60.30.3-1.00.7-0.91.2-0.9-0.90.50.7-0.7-0.2
Mean time between licks in bursts0.20.51.60.3-0.6-0.40.30.00.5-0.6-0.6-0.1-0.0-0.8-0.51.01.0-0.3-1.31.31.0
Mean num. licks in bursts0.30.51.4-0.41.20.5-1.10.2-0.10.50.20.8-0.31.0-1.1-0.0-0.0-0.61.1-1.10.1
Cd content in liver3.33.710.7-2.00.62.1-1.12.5-2.11.7-2.9-2.7-1.9-3.3-0.5-1.3-1.32.0-1.21.2-1.2
Co content in liver2.42.85.6-2.22.42.1-2.02.0-1.81.7-1.9-1.7-1.4-2.3-2.2-0.9-0.90.50.7-0.7-0.1
Cu content in liver0.70.83.6-0.80.30.9-0.10.9-1.10.7-0.9-1.6-0.4-1.90.4-0.9-0.90.9-0.10.1-0.3
Fe content in liver1.82.25.70.61.5-0.5-0.4-1.20.9-0.61.91.71.61.8-1.40.70.7-2.12.4-2.41.7
K content in liver0.60.61.6-0.81.30.7-0.90.6-0.90.8-0.4-0.8-0.3-0.6-0.3-1.0-1.00.41.0-1.0-0.3
Mg content in liver0.50.52.0-0.51.40.4-0.50.2-0.50.30.1-0.50.3-0.6-0.5-0.6-0.6-0.21.4-1.40.5
Mn content in liver0.30.31.40.2-0.6-0.51.1-0.40.2-0.60.1-0.70.8-1.20.70.20.2-0.0-0.30.30.7
Na content in liver0.30.31.70.40.2-0.4-0.0-0.70.5-0.20.90.80.51.30.1-0.0-0.0-0.50.8-0.80.1
Rb content in liver0.30.30.80.9-0.4-0.80.6-0.60.7-0.90.40.30.5-0.00.10.70.7-0.6-0.10.10.7
Se content in liver1.92.38.50.51.5-0.30.4-1.30.4-0.82.20.52.60.3-0.20.00.0-1.72.9-2.91.9
Sr content in liver1.10.93.3-1.10.81.1-0.61.0-1.41.0-0.9-1.6-0.5-1.8-0.1-0.9-0.90.80.2-0.2-0.5
Zn content in liver1.21.42.7-1.51.01.4-1.01.4-1.41.3-1.3-1.6-0.9-1.7-0.2-1.3-1.31.20.2-0.2-0.6
Bone: minimum diameter0.71.34.01.1-1.5-1.02.0-1.41.0-1.21.60.41.80.41.60.60.6-0.5-0.20.21.0
Time in familiar zone, hab. session 11.01.02.01.2-1.0-1.30.6-0.71.2-1.3-0.00.80.00.3-0.61.41.4-0.7-1.31.30.7
Time in novel zone, hab. session 10.90.92.0-1.20.91.3-1.31.1-0.91.4-0.60.1-1.30.8-0.4-0.9-0.90.60.4-0.4-1.2
Total zone transitions, hab. session 10.20.31.30.2-1.1-0.40.7-0.40.4-0.20.40.40.20.71.00.20.20.2-0.80.8-0.4
Total locomotion distance, hab. session 10.10.10.6-0.1-0.80.10.3-0.00.20.20.20.2-0.00.60.7-0.0-0.00.2-0.50.5-0.3
Locomotion velocity, hab. session 10.10.21.3-0.0-0.9-0.00.7-0.30.2-0.00.50.00.40.31.1-0.1-0.10.2-0.40.4-0.1
Time in familiar zone, hab. session 21.11.12.31.5-1.2-1.31.5-1.21.3-1.50.90.61.10.30.41.01.0-0.9-0.70.71.0
Time in novel zone, hab. session 22.82.84.6-2.11.02.0-1.62.1-2.02.2-2.0-1.6-2.1-1.2-0.0-1.6-1.62.0-0.20.2-2.0
Total zone transitions, hab. session 20.70.92.70.6-1.7-0.91.1-0.71.1-0.90.40.60.50.30.51.21.2-0.5-1.51.50.6
Total locomotion distance, hab. session 20.30.31.60.3-1.1-0.21.1-0.30.2-0.30.3-0.30.6-0.41.30.00.00.2-0.60.60.2
Locomotion velocity, hab. session 20.30.41.90.4-1.0-0.31.2-0.50.2-0.40.6-0.30.8-0.21.4-0.1-0.10.2-0.40.40.2
Novel to familiar place preference ratio0.80.82.3-0.8-0.20.9-0.91.1-0.71.0-1.3-0.4-1.5-0.2-0.0-0.3-0.31.1-1.01.0-1.4
Novelty place preference0.80.92.6-0.7-0.40.8-0.81.0-0.71.0-1.3-0.4-1.6-0.00.3-0.5-0.51.3-1.11.1-1.6
Time in novel zone, NPP test1.01.03.4-0.90.01.0-1.21.2-0.81.2-1.4-0.2-1.80.2-0.2-0.5-0.51.2-0.90.9-1.7
Total zone transitions, NPP test0.50.82.90.7-1.2-0.61.7-0.80.6-0.90.8-0.31.5-0.71.30.50.5-0.3-0.40.41.0
Total locomotion distance, NPP test0.10.10.40.0-0.70.30.70.10.2-0.00.1-0.20.4-0.40.60.20.20.0-0.50.50.4
Locomotion velocity, NPP test0.30.41.40.1-0.70.21.0-0.1-0.1-0.10.3-0.91.0-1.21.2-0.1-0.10.2-0.10.10.6
Intraocular pressure1.42.03.9-1.81.61.6-2.01.8-1.51.7-2.0-1.3-1.7-1.3-1.5-0.9-0.90.90.1-0.1-0.9
Delta distance traveled before/after self-admin0.10.10.40.3-0.6-0.40.3-0.30.4-0.30.20.40.10.50.10.40.4-0.2-0.60.6-0.1
Delta ambulatory time before/after self-admin0.60.81.30.9-1.1-1.00.7-0.81.2-1.00.71.00.50.9-0.11.11.1-0.9-1.01.00.6
Parametrial fat weight0.30.72.80.9-0.8-0.71.6-0.8-0.1-0.90.8-0.81.2-0.81.7-0.5-0.50.3-0.10.10.2
Pavlov. Cond. lever latency0.60.83.60.7-1.4-0.60.60.10.2-0.4-0.8-0.1-0.9-0.00.80.20.20.8-1.91.9-1.0
Pavlov. Cond. magazine entry latency0.50.72.2-0.91.51.1-1.30.6-0.30.8-0.10.4-0.40.4-1.5-0.1-0.1-0.61.1-1.10.2
Pavlov. Cond. change in total contacts0.90.92.6-0.10.90.1-0.1-0.50.5-0.21.10.71.30.4-0.90.60.6-1.51.6-1.61.6
Pavlov. Cond. index score0.81.03.4-1.11.81.0-1.20.5-0.50.80.10.00.2-0.1-1.4-0.2-0.2-0.71.7-1.70.7
Pavlov. Cond. latency score0.60.72.5-1.01.50.9-0.80.4-0.40.70.3-0.10.5-0.2-1.0-0.3-0.3-0.61.6-1.60.8
Pavlov. Cond. lever contacts0.81.04.1-1.01.70.9-1.00.3-0.40.80.50.20.50.2-1.1-0.3-0.3-0.82.0-2.00.8
Pavlov. Cond. magazine entry number1.21.55.51.4-2.4-1.51.8-1.00.9-1.30.30.10.40.01.70.60.60.4-1.91.9-0.1
Pavlov. Cond. intertrial magazine entries0.60.72.00.20.8-0.30.6-0.50.0-0.70.6-0.51.4-1.3-0.20.20.2-0.81.4-1.41.4
Pavlov. Cond. lever-magazine prob. diff.1.21.55.0-1.52.21.4-1.50.8-0.91.2-0.0-0.30.1-0.3-1.4-0.7-0.7-0.52.1-2.10.5
Pavlov. Cond. response bias1.11.44.7-1.12.21.0-1.70.5-0.30.90.20.6-0.10.6-2.0-0.1-0.1-1.01.9-1.90.6
Pavlov. Cond. lever latency0.20.30.7-0.50.40.5-0.20.4-0.80.5-0.3-0.8-0.3-0.80.4-0.7-0.70.60.4-0.4-0.5
Pavlov. Cond. magazine entry latency0.00.10.2-0.4-0.20.30.10.20.10.2-0.1-0.20.1-0.4-0.00.00.00.0-0.40.40.4
Pavlov. Cond. change in total contacts0.20.41.20.40.2-0.4-0.2-0.30.9-0.50.20.90.10.8-1.10.80.8-0.9-0.20.20.8
Pavlov. Cond. index score0.20.20.60.3-0.1-0.3-0.1-0.30.7-0.40.20.80.20.7-0.60.60.6-0.7-0.20.20.6
Pavlov. Cond. latency score0.20.30.60.3-0.1-0.20.0-0.30.7-0.40.40.80.40.7-0.60.70.7-0.8-0.00.00.8
Pavlov. Cond. lever contacts0.30.40.80.6-0.7-0.60.3-0.40.9-0.60.20.80.10.8-0.20.70.7-0.5-0.70.70.3
Pavlov. Cond. magazine entry number0.00.10.3-0.0-0.20.1-0.10.2-0.20.2-0.3-0.0-0.40.00.10.10.10.2-0.30.3-0.6
Pavlov. Cond. intertrial magazine entries1.21.83.81.7-1.7-1.62.0-1.61.5-1.71.51.01.40.71.01.41.4-1.0-0.80.80.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.20.0-0.2-0.1-0.20.6-0.30.10.60.10.6-0.70.50.5-0.6-0.10.10.6
Pavlov. Cond. response bias0.00.10.20.2-0.2-0.30.1-0.20.4-0.30.10.30.10.3-0.10.20.2-0.2-0.30.30.2
Time in closed arm before self-admin0.91.22.50.9-0.1-0.80.3-0.91.4-1.11.01.50.81.2-1.11.51.5-1.60.3-0.31.3
Time in closed arm after self-admin0.40.51.30.20.1-0.2-0.2-0.20.9-0.40.20.90.20.4-1.11.11.1-1.1-0.10.11.1
Time in open arm before self-admin0.60.71.6-1.00.30.9-1.01.1-0.71.0-1.3-0.5-1.3-0.3-0.6-0.5-0.50.6-0.80.8-0.9
Time in open arm after self-admin0.30.41.0-0.2-0.00.20.10.2-0.70.4-0.2-0.8-0.2-0.50.9-1.0-1.01.00.1-0.1-0.9
Bone: periosteal estimation0.40.83.40.5-1.4-0.61.7-0.80.4-0.70.9-0.41.3-0.41.8-0.1-0.10.3-0.40.40.4
Bone: periosteal perimeter0.50.83.10.3-0.7-0.41.7-0.60.4-0.90.7-0.81.8-1.51.00.20.2-0.30.1-0.11.5
Bone: post-yield work0.30.51.30.9-1.0-0.70.7-0.80.4-0.50.90.60.41.11.20.10.10.0-0.30.3-0.5
Progressive ratio test 1 active lever presses1.11.42.1-1.31.21.3-1.01.1-1.41.4-0.9-1.2-0.9-0.80.2-1.5-1.51.21.2-1.2-1.3
Progressive ratio test 1 breakpoint1.31.52.3-1.41.31.4-1.01.2-1.51.5-1.0-1.2-1.0-0.80.1-1.5-1.51.31.3-1.3-1.4
Progressive ratio test 1 inactive lever presses1.01.47.8-0.81.80.8-0.70.5-0.90.8-0.1-0.7-0.1-0.5-0.1-1.0-1.00.52.8-2.8-0.3
Progressive ratio test 2 active lever presses1.11.32.0-1.30.91.4-1.01.2-1.41.4-1.0-1.1-1.0-0.80.2-1.3-1.31.20.7-0.7-1.4
Progressive ratio test 2 breakpoint1.21.42.2-1.40.91.4-1.01.3-1.51.5-1.1-1.2-1.1-0.80.2-1.4-1.41.30.7-0.7-1.5
Progressive ratio test 2 inactive lever presses1.32.23.6-1.81.41.9-1.61.8-1.71.9-1.5-1.3-1.5-1.0-0.3-1.6-1.61.41.0-1.0-1.4
Incentive Sensitization - Responses0.20.20.6-0.5-0.00.5-0.30.5-0.60.5-0.5-0.5-0.5-0.30.2-0.5-0.50.6-0.20.2-0.8
Incentive Sensitization - Breakpoint0.10.20.5-0.4-0.10.4-0.30.4-0.50.4-0.4-0.4-0.4-0.30.2-0.4-0.40.5-0.20.2-0.7
Sum of active levers in priming session hrs 5-60.40.42.00.2-1.0-0.40.4-0.00.1-0.1-0.3-0.3-0.3-0.00.7-0.3-0.30.6-1.41.4-0.6
Progressive ratio0.40.72.30.9-1.5-0.91.3-0.70.4-0.80.4-0.10.4-0.21.30.20.20.3-1.21.2-0.0
Food seeking constrained by brief footshock1.51.84.01.7-0.8-1.61.8-1.61.2-1.81.70.82.00.20.51.31.3-1.40.4-0.41.6
Seeking ratio, punishment vs. effort0.50.72.70.50.7-0.50.5-0.70.3-0.61.10.41.30.2-0.20.40.4-1.01.6-1.61.0
Retroperitoneal fat weight0.31.36.00.1-0.80.11.7-0.1-0.8-0.30.4-2.01.4-2.52.2-0.9-0.90.8-0.20.20.0
Reaction time number correct0.40.82.7-1.41.41.3-1.41.1-0.51.0-0.9-0.2-0.7-0.6-1.60.10.1-0.30.3-0.30.2
Reaction time mean minus median0.51.32.8-1.11.51.1-0.90.9-1.51.1-0.7-1.3-0.7-0.9-0.1-1.7-1.71.21.1-1.1-0.7
Reaction time mean minus median AUC1.02.54.3-1.82.01.9-1.41.6-2.11.7-1.1-1.8-0.9-1.6-0.3-2.0-2.01.41.4-1.4-1.0
Reaction time num false alarms2.02.87.2-2.10.42.4-0.92.3-1.71.8-2.2-2.3-1.4-2.7-0.1-1.2-1.21.6-1.11.1-0.7
Reaction time num false alarms AUC1.42.15.4-1.90.52.3-1.22.2-1.31.7-2.0-1.6-1.5-2.0-0.8-0.7-0.71.0-1.11.1-0.5
Reaction time trials correct on left0.40.82.7-1.41.41.3-1.41.1-0.51.0-0.9-0.2-0.7-0.6-1.60.10.1-0.30.3-0.30.2
Reaction time trials on left0.50.92.5-1.51.41.4-1.41.3-0.71.1-1.0-0.3-0.8-0.7-1.6-0.1-0.1-0.10.3-0.30.1
Reaction time mean3.14.98.1-2.62.22.7-2.22.5-2.92.7-2.2-2.5-2.1-2.1-0.3-2.6-2.62.30.9-0.9-1.7
Reaction time mean AUC2.94.67.5-2.52.22.6-2.22.4-2.72.6-2.1-2.4-2.0-2.0-0.4-2.5-2.52.10.9-0.9-1.7
Median of all reaction times3.44.87.7-2.62.12.7-2.32.6-2.82.7-2.3-2.4-2.2-2.1-0.5-2.4-2.42.10.7-0.7-1.7
Reaction time omissions2.43.56.5-2.00.82.1-1.12.0-2.42.1-1.8-2.6-1.6-2.20.7-2.5-2.52.40.0-0.0-1.9
Reaction time false alarm rate0.50.71.8-1.0-0.01.4-0.41.3-0.80.9-1.2-1.1-0.7-1.3-0.0-0.5-0.50.8-0.80.8-0.3
Reaction time premature initiation rate4.56.310.23.1-2.3-3.22.9-3.23.0-3.22.92.22.81.80.82.52.5-2.2-0.70.72.6
Reaction time premature initiations2.03.65.72.1-1.6-2.21.9-2.22.4-2.32.11.82.01.30.12.22.2-2.0-0.70.72.2
Std. dev. reaction times1.12.03.7-1.51.51.6-1.31.4-1.91.6-1.1-1.6-1.2-1.1-0.0-1.9-1.91.60.8-0.8-1.1
Reaction time trials completed0.50.92.5-1.51.41.4-1.41.3-0.71.1-1.0-0.3-0.8-0.7-1.6-0.1-0.1-0.10.3-0.30.1
Reaction time trials AUC0.51.02.5-1.61.41.6-1.51.4-0.81.3-1.1-0.5-0.9-0.8-1.5-0.2-0.20.00.3-0.3-0.1
Run reversals in cocaine runway, females2.22.25.7-1.00.30.90.10.7-1.91.2-0.5-2.1-0.3-1.42.2-2.4-2.42.10.8-0.8-1.7
Run reversals in cocaine runway, males0.80.81.7-1.10.61.1-1.21.2-0.81.1-1.3-0.7-1.2-0.6-0.6-0.6-0.60.8-0.30.3-1.0
Latency to leave start box in cocaine runway1.21.44.2-0.7-0.30.7-0.00.7-1.51.0-0.7-1.5-0.8-1.01.7-1.7-1.71.8-0.30.3-2.1
Latency to leave start box in cocaine runway, F1.11.33.4-0.90.70.8-0.70.8-1.51.1-0.8-1.3-0.9-0.70.9-1.8-1.81.40.5-0.5-1.6
Latency to leave start box in cocaine runway, M0.60.62.50.2-1.5-0.21.1-0.2-0.1-0.10.2-0.50.2-0.41.6-0.1-0.10.7-1.21.2-0.9
Std. dev. time between licks in bursts0.81.12.60.9-1.6-0.91.3-0.81.3-1.10.40.50.70.10.41.31.3-0.6-1.61.61.1
Total sessions with >9 infusions1.72.16.6-1.62.61.6-1.81.4-1.21.4-1.0-0.5-1.0-0.6-1.7-0.6-0.60.22.4-2.4-0.4
Short access day 1 total inactive lever presses1.31.79.9-0.21.60.20.2-0.1-1.00.40.4-0.80.5-0.41.0-1.4-1.40.73.2-3.2-0.4
Short access day 10 total inactive lever presses0.82.03.11.5-0.3-1.51.1-1.61.7-1.71.71.41.71.0-0.51.61.6-1.81.2-1.21.7
Short access day 1 total infusions2.83.714.9-1.63.71.7-2.01.4-1.61.5-0.9-0.6-0.9-0.7-1.8-1.0-1.00.13.9-3.9-0.3
Short access day 10 total infusions0.60.81.4-1.11.21.2-1.00.9-1.01.1-0.6-0.6-0.6-0.5-0.4-0.8-0.80.51.1-1.1-0.6
Short access total infusions1.21.54.3-1.31.91.3-1.31.1-1.31.3-0.8-0.8-0.8-0.6-0.7-1.0-1.00.62.1-2.1-0.6
Short access day 1 locomotion2.93.59.8-1.93.12.1-2.21.8-1.81.9-1.4-1.0-1.4-1.0-1.4-1.3-1.30.73.0-3.0-1.0
Short access day 10 total locomotion0.61.02.5-1.30.61.3-1.51.5-0.51.2-1.6-0.3-1.6-0.5-1.5-0.2-0.20.4-0.50.5-0.5
Short access total locomotion1.82.24.3-1.72.11.8-2.01.8-1.31.7-1.7-0.8-1.7-0.8-1.7-0.9-0.90.71.5-1.5-0.8
One hour access (0.3 mA shock)0.70.81.3-1.10.51.1-0.91.1-1.01.1-1.0-0.9-1.0-0.60.0-0.9-0.91.0-0.30.3-1.1
Compulsive drug intake0.70.83.70.10.5-0.2-0.5-0.20.9-0.40.21.00.20.6-1.91.31.3-1.30.0-0.01.5
One hour access (shock baseline)0.81.33.3-1.0-0.01.0-0.51.1-1.41.2-1.0-1.3-1.0-0.81.0-1.5-1.51.6-0.50.5-1.8
Social response proportion0.91.02.8-0.6-0.00.90.01.0-1.20.8-1.0-1.7-0.6-1.50.9-1.5-1.51.4-0.30.3-0.8
Social responses0.91.26.60.0-1.6-0.00.40.50.1-0.0-1.2-0.8-0.9-1.00.40.10.10.9-2.62.6-0.3
Social time0.50.61.60.7-0.4-0.50.3-0.41.1-0.80.21.00.20.6-1.01.21.2-1.1-0.50.50.9
Soleus weight0.10.30.9-0.3-0.60.30.10.5-0.30.3-0.8-0.4-0.7-0.50.5-0.1-0.10.6-1.01.0-0.7
Bone: stiffness0.50.85.10.2-0.5-0.10.9-0.5-0.50.00.9-0.80.7-0.12.3-1.3-1.30.90.6-0.6-1.0
Tibialis anterior weight0.20.62.3-1.00.81.0-0.60.9-0.90.7-0.8-1.1-0.2-1.5-0.5-0.5-0.50.50.2-0.20.3
Time to tail flick, vehicle, before self-admin0.30.30.70.8-0.7-0.80.6-0.70.7-0.70.60.60.30.70.30.40.4-0.2-0.50.5-0.1
Time to tail flick, vehicle, after self-admin0.70.93.50.9-1.9-0.91.1-0.60.7-0.70.30.00.20.31.20.20.20.5-1.81.8-0.0
Time to tail flick, test, before self-admin3.03.15.8-1.71.81.9-1.41.7-2.41.9-1.4-2.0-1.3-1.50.4-2.3-2.31.81.5-1.5-1.8
Time to tail flick, test, after self-admin0.10.10.20.2-0.4-0.10.20.00.0-0.1-0.2-0.2-0.2-0.20.2-0.2-0.20.2-0.40.4-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.30.2-0.3-0.20.4-0.20.0-0.10.1-0.40.3-0.30.5-0.3-0.30.20.0-0.00.3
Delta time to tail flick, test, before/after SA0.50.51.30.3-0.7-0.40.0-0.20.9-0.5-0.10.6-0.10.3-0.81.01.0-0.7-1.21.20.7
Tibia length0.30.93.60.51.0-0.60.0-1.10.2-0.41.50.51.30.80.1-0.2-0.2-0.81.9-1.90.5
Ambulatory time before self-admin1.11.63.1-1.51.71.5-1.41.4-1.61.5-1.1-0.9-1.1-0.7-0.4-1.3-1.31.01.3-1.3-0.8
Ambulatory time after self-admin0.20.20.4-0.50.50.4-0.60.5-0.50.6-0.4-0.0-0.50.3-0.2-0.4-0.40.30.3-0.3-0.5
Bone: tissue strength1.21.22.8-1.11.71.1-0.80.9-1.20.9-0.6-1.40.1-1.6-0.5-1.2-1.20.41.4-1.40.2
Total heroin consumption0.40.41.9-0.3-0.70.30.10.4-0.30.3-0.6-0.7-0.5-0.50.5-0.5-0.50.9-1.41.4-0.3
Bone: trabecular number5.18.519.73.0-1.6-3.11.3-3.13.8-3.02.94.41.84.4-1.33.63.6-3.5-0.40.42.4
Bone: trabecular spacing3.74.99.8-2.51.42.4-1.32.5-2.92.5-2.5-3.1-1.6-3.10.7-2.5-2.52.50.2-0.2-2.0
Bone: trabecular thickness0.81.03.71.0-0.9-0.80.7-1.11.1-0.81.41.50.71.90.30.90.9-0.90.0-0.00.4
Bone: trabecular tissue density2.13.17.3-1.50.91.5-1.21.6-2.31.9-1.6-2.0-1.8-1.21.0-2.4-2.42.40.3-0.3-2.7
Water consumed over 24 hours0.71.02.60.9-1.6-0.80.8-0.71.2-0.80.51.20.11.40.41.01.0-0.4-1.51.5-0.0
Number of responses in last shaping day1.31.44.9-0.72.20.8-1.40.6-0.10.5-0.30.4-0.30.0-2.10.30.3-0.82.2-2.20.9