Nfe2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS NM_001372250.1 0.02 0.02 3.2e-03 0.02 0.01 0.01 -0 3.3e-03 1.0e-02 9.7e-03 5.1e-01
2 NAcc mRNA stability Nfe2l1 0.02 0.01 7.7e-03 0.01 0.01 0.01 0.01 2.3e-02 3.0e-02 2.4e-02 3.2e-02
3 LHb gene expression Nfe2l1 0.54 0.16 1.5e-12 0.32 0.34 0.34 0.33 1.8e-08 8.1e-09 5.3e-09 9.4e-09
4 BLA mRNA stability Nfe2l1 0.08 0.06 1.5e-04 0.06 0.05 0.05 0.05 6.4e-04 8.0e-04 1.1e-03 1.4e-03
5 IL gene expression Nfe2l1 0.72 0.11 0.0e+00 0.34 0.4 0.37 0.39 7.5e-09 9.2e-11 6.7e-10 2.4e-10
6 BLA gene expression Nfe2l1 0.51 0.1 0.0e+00 0.58 0.6 0.6 0.6 7.2e-38 3.7e-39 8.4e-40 1.3e-39
7 Adipose isoform ratio XM_039086388.1 0.02 0.02 4.4e-03 0.01 0.01 0.01 -0 2.5e-02 1.2e-02 3.5e-02 9.0e-01
8 Adipose alternative polyA XM_039086388.1 0.03 0.02 8.7e-04 0.01 0.02 0.01 0 8.7e-03 2.1e-03 1.4e-02 2.5e-01
9 Adipose alternative polyA NM_001108293.2 0.03 0.02 8.2e-04 0.01 0.02 0 0 1.8e-02 2.4e-03 1.9e-01 1.0e-01
10 RMTg isoform ratio NM_001108293.2 0.1 0.07 4.1e-03 0.06 0.08 0.04 0.07 1.4e-02 4.3e-03 3.1e-02 6.4e-03
11 Liver alternative TSS NM_001108293.2 0.04 0.04 7.6e-04 0.03 0.02 0.03 0.03 1.9e-04 1.8e-03 2.0e-04 3.5e-04
12 Liver isoform ratio NM_001108293.2 0.05 0.08 4.7e-03 0.02 0.01 0.02 0.02 1.7e-03 2.4e-02 2.9e-03 3.6e-03
13 PL mRNA stability Nfe2l1 0.03 0.03 1.6e-04 0.03 0.03 0.02 0.03 3.5e-04 2.6e-04 2.0e-03 4.4e-04
14 Brain gene expression Nfe2l1 0.6 0.11 0.0e+00 0.72 0.73 0.73 0.73 2.2e-94 2.0e-97 3.3e-97 2.0e-97
15 RMTg gene expression Nfe2l1 0.2 0.11 3.4e-05 0.14 0.12 0.11 0.12 1.8e-04 4.2e-04 6.1e-04 5.6e-04
16 NAcc gene expression Nfe2l1 0.19 0.07 0.0e+00 0.32 0.33 0.33 0.33 2.9e-38 6.4e-39 6.6e-39 7.8e-39
17 pVTA intron excision ratio chr10_81805225_81806459 0.18 0.11 4.3e-03 0.06 0.05 0.06 0.06 1.3e-03 2.4e-03 1.4e-03 1.8e-03
18 Eye gene expression Nfe2l1 0.71 0.15 3.1e-07 0.13 0.09 0.12 0.12 5.2e-03 1.5e-02 7.0e-03 5.8e-03
19 pVTA gene expression Nfe2l1 0.36 0.12 0.0e+00 0.44 0.48 0.47 0.48 5.4e-21 5.7e-23 7.6e-23 5.3e-23
20 Liver alternative polyA NM_001108293.2 0.06 0.04 6.6e-09 0.06 0.08 0.07 0.07 9.6e-08 4.6e-09 4.0e-08 6.6e-08
21 OFC gene expression Nfe2l1 0.68 0.11 0.0e+00 0.42 0.44 0.45 0.45 3.4e-11 9.5e-12 3.6e-12 3.9e-12
22 Liver alternative TSS NM_001372251.1 0.08 0.09 5.4e-03 0.02 0.01 0.01 0.01 4.0e-03 2.7e-02 1.0e-02 1.8e-02
23 PL gene expression Nfe2l1 0.39 0.05 0.0e+00 0.63 0.65 0.64 0.64 2.2e-89 2.2e-94 7.3e-93 1.8e-92
24 RMTg mRNA stability Nfe2l1 0.11 0.08 2.6e-03 0.09 0.07 0.04 0.08 2.2e-03 7.2e-03 2.5e-02 4.3e-03
25 Liver alternative polyA XM_039086388.1 0.07 0.05 5.5e-09 0.06 0.08 0.07 0.07 1.0e-07 4.6e-09 2.1e-08 2.7e-08
26 OFC alternative TSS NM_001372251.1 0.44 0.2 4.6e-03 0.09 0.03 0.03 0.08 4.1e-03 8.3e-02 8.2e-02 4.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.42.43.01.6-1.61.5-1.7-1.61.71.61.6-1.6-1.6-1.7-1.71.6-1.51.4-1.6-1.31.4-1.5-1.51.41.3-1.51.61.51.3
Area under the delay curve0.40.41.3-0.70.6-0.80.40.6-0.5-0.6-0.70.70.60.40.4-0.60.5-0.30.51.1-0.50.60.5-0.6-0.60.5-0.5-0.4-1.1
BMI with tail12.741.362.17.9-7.56.8-6.5-7.06.56.86.7-6.7-6.7-6.4-6.46.6-6.66.4-6.4-4.36.2-6.3-6.36.46.2-6.06.06.14.3
BMI without tail1.22.63.31.6-1.81.6-1.6-1.61.51.61.5-1.5-1.7-1.7-1.71.6-1.71.7-1.7-0.41.7-1.6-1.81.81.7-1.61.81.80.3
Body weight0.52.15.21.9-1.91.3-1.5-1.31.01.20.9-0.9-1.3-1.4-1.41.1-1.41.4-1.42.31.5-1.3-1.51.41.4-1.21.31.5-2.2
Weight adjusted by age0.70.81.5-0.40.7-1.11.20.8-1.1-0.9-0.90.90.90.90.9-0.90.9-0.91.00.6-0.91.01.0-0.8-0.71.0-1.1-1.0-0.8
Bone surface0.30.51.11.0-0.60.7-1.0-0.80.80.70.7-0.7-0.8-0.8-0.80.7-0.70.6-0.70.10.6-0.7-0.80.60.5-0.60.90.7-0.1
Bone volume1.11.82.71.6-1.31.3-1.6-1.41.41.41.4-1.4-1.4-1.5-1.51.4-1.41.3-1.4-0.51.3-1.3-1.41.31.2-1.31.51.40.5
Breakpoint value in progressive ratio session4.44.96.4-1.61.8-2.22.12.1-2.2-2.2-2.22.22.22.22.2-2.32.3-2.52.31.9-2.52.42.3-2.1-2.12.5-2.5-2.4-1.9
Number of licking bursts0.10.10.2-0.30.4-0.30.40.3-0.3-0.3-0.20.20.30.40.4-0.20.3-0.40.3-0.5-0.20.30.3-0.3-0.20.3-0.3-0.30.4
Context. condit. distance diff. score0.20.31.11.0-0.90.6-0.4-0.60.40.60.6-0.6-0.6-0.4-0.40.6-0.50.4-0.5-0.10.4-0.4-0.50.40.4-0.30.70.40.2
Locomotion velocity, session 10.40.40.70.2-0.60.7-0.7-0.60.70.60.6-0.6-0.7-0.7-0.70.7-0.70.8-0.7-0.50.6-0.8-0.80.70.8-0.80.40.80.5
Locomotion distance, session 12.53.34.3-2.01.9-2.01.71.9-1.8-1.9-2.02.01.91.61.6-1.91.7-1.51.72.1-1.71.71.7-1.7-1.61.6-1.8-1.6-2.1
Locomotion velocity, session 21.11.33.4-1.31.3-1.21.01.2-1.2-1.2-1.31.21.10.90.9-1.11.0-0.90.91.9-1.01.00.9-0.9-0.90.9-1.1-0.8-1.8
Locomotion distance, session 23.14.45.8-2.42.2-2.21.92.3-2.1-2.2-2.32.32.21.91.9-2.22.0-1.82.02.2-2.12.02.0-2.0-1.91.9-2.1-1.9-2.2
Locomotion velocity, session 30.00.00.50.20.1-0.20.00.1-0.1-0.1-0.10.20.10.10.1-0.10.1-0.10.10.7-0.10.10.1-0.1-0.10.2-0.2-0.2-0.6
Locomotion distance, session 33.33.64.7-1.51.8-2.01.81.9-1.9-1.9-2.02.01.92.02.0-1.91.8-1.71.82.2-1.91.91.8-1.9-2.01.9-1.9-1.8-2.2
Stereotopy head waving bouts, day 34.55.46.62.2-2.52.6-2.4-2.32.42.42.4-2.4-2.4-2.4-2.42.3-2.32.1-2.3-1.92.3-2.3-2.32.42.4-2.22.32.22.0
Stereotopy head waving duration, day 33.33.94.61.9-2.12.2-2.1-2.02.12.02.0-2.0-2.0-2.1-2.12.0-2.01.9-2.0-1.31.9-2.0-2.02.12.1-1.91.92.01.3
Locomotion velocity, session 71.41.52.1-0.81.0-1.31.21.2-1.3-1.2-1.31.31.21.21.2-1.31.2-1.21.21.4-1.21.21.3-1.2-1.21.3-1.3-1.3-1.5
Locomotion distance, session 75.26.67.4-2.52.3-2.62.52.7-2.6-2.7-2.72.72.62.62.6-2.72.6-2.52.62.5-2.52.62.5-2.6-2.62.5-2.5-2.5-2.5
Stereotopy head waving bouts, day 70.70.71.50.7-0.60.8-0.9-0.90.90.90.9-0.9-0.8-0.9-0.90.9-0.80.7-0.8-1.20.8-0.8-0.80.90.9-0.80.70.71.2
Stereotopy head waving duration, day 70.30.41.10.5-0.30.6-0.6-0.60.70.60.7-0.7-0.6-0.6-0.60.6-0.60.4-0.5-1.00.6-0.6-0.50.70.7-0.50.30.41.0
Locomotion velocity, session 80.10.21.11.0-0.80.4-0.3-0.50.20.40.3-0.3-0.4-0.3-0.30.3-0.30.3-0.30.50.3-0.3-0.30.30.3-0.10.20.2-0.4
Locomotion distance, session 80.71.02.4-0.70.8-1.01.01.0-1.1-1.0-1.11.11.01.01.0-1.00.9-0.80.91.5-0.91.00.9-0.9-0.90.9-0.8-0.8-1.4
Degree of sensitization distance0.00.00.1-0.0-0.30.00.00.1-0.1-0.1-0.10.10.1-0.1-0.1-0.10.1-0.10.10.3-0.10.10.10.00.00.1-0.1-0.1-0.3
Degree of sensitization stereotypy0.10.11.0-0.30.4-0.30.20.1-0.1-0.1-0.00.00.20.20.2-0.10.2-0.30.2-1.0-0.20.30.3-0.2-0.20.2-0.3-0.31.0
Conditioned locomotion1.01.21.81.3-1.31.2-1.1-1.21.01.11.1-1.1-1.1-1.0-1.01.1-1.11.1-1.1-0.41.2-1.1-1.11.11.0-1.01.21.10.3
Cocaine response after cond. corrected5.56.17.72.5-2.42.7-2.5-2.62.42.62.5-2.5-2.6-2.5-2.52.6-2.52.6-2.6-1.22.6-2.5-2.62.62.6-2.52.82.61.1
Cocaine response after cond. not corrected2.93.24.41.7-1.72.0-1.8-1.81.71.81.8-1.8-1.9-1.9-1.91.9-1.81.9-1.9-0.61.9-1.8-2.01.91.9-1.92.12.00.5
Cocaine response before conditioning2.42.94.3-2.11.9-1.81.61.9-1.7-1.8-1.81.81.81.61.6-1.81.8-1.81.71.2-1.61.71.7-1.8-1.81.6-1.8-1.6-1.2
Saline control response0.10.20.40.10.2-0.30.30.3-0.3-0.3-0.30.30.40.30.3-0.40.4-0.60.5-0.1-0.50.40.6-0.5-0.50.6-0.5-0.6-0.0
Bone: connectivity density0.10.20.80.4-0.40.4-0.5-0.40.50.40.5-0.5-0.4-0.4-0.40.4-0.30.2-0.3-0.90.2-0.3-0.30.20.1-0.30.50.30.8
Bone: cortical apparent density5.97.710.2-2.32.7-2.63.22.6-2.8-2.7-2.52.52.83.23.2-2.72.9-3.13.00.2-3.13.03.1-2.9-3.03.1-3.0-3.2-0.4
Bone: cortical area0.00.10.30.50.00.0-0.4-0.30.20.20.2-0.2-0.2-0.4-0.40.2-0.30.2-0.30.50.2-0.2-0.20.10.2-0.20.20.2-0.4
Bone: cortical porosity0.40.50.70.4-0.30.6-0.8-0.60.70.70.7-0.7-0.7-0.7-0.70.7-0.70.8-0.7-0.50.8-0.8-0.80.70.7-0.80.70.80.6
Bone: cortical porosity0.30.30.60.2-0.30.5-0.7-0.50.60.50.5-0.5-0.6-0.6-0.60.6-0.70.7-0.7-0.30.7-0.7-0.70.60.6-0.80.60.70.3
Bone: cortical thickness0.20.30.60.10.4-0.50.60.4-0.6-0.5-0.50.50.50.50.5-0.50.5-0.60.60.8-0.70.60.6-0.6-0.60.7-0.7-0.7-0.7
Bone: cortical thickness1.31.52.8-1.71.1-1.31.11.4-1.2-1.3-1.31.31.31.11.1-1.31.2-1.11.11.4-1.11.01.1-1.2-1.11.1-1.1-1.0-1.3
Bone: cortical tissue density6.28.210.8-2.42.8-2.73.32.7-2.9-2.8-2.62.62.93.33.3-2.83.0-3.23.10.2-3.23.13.1-3.0-3.13.1-3.0-3.2-0.4
Condit. Reinf. active minus inactive responses0.10.20.6-0.80.7-0.50.30.5-0.3-0.4-0.40.40.40.30.3-0.40.4-0.40.4-0.2-0.40.40.3-0.4-0.40.3-0.3-0.30.2
Condit. Reinf. active-inactive response ratio0.20.20.6-0.10.00.3-0.5-0.30.50.40.4-0.4-0.4-0.6-0.60.4-0.40.4-0.4-0.80.3-0.4-0.40.50.5-0.50.30.50.8
Condit. Reinf. active responses0.10.10.5-0.70.6-0.30.20.4-0.1-0.3-0.30.30.30.30.3-0.30.3-0.30.3-0.4-0.30.30.3-0.4-0.40.2-0.2-0.20.4
Condit. Reinf. inactive responses0.30.40.7-0.60.5-0.50.60.6-0.5-0.6-0.50.50.60.80.8-0.60.7-0.60.6-0.1-0.60.60.6-0.8-0.80.6-0.5-0.60.1
Incentive salience index mean0.30.41.5-1.21.2-0.80.60.8-0.5-0.7-0.60.60.70.50.5-0.60.6-0.50.6-0.2-0.70.60.6-0.6-0.50.4-0.6-0.50.2
Condit. Reinf. lever presses0.81.12.2-1.41.5-1.31.11.1-0.9-1.1-1.01.01.11.01.0-1.11.0-0.91.1-0.1-1.31.11.1-1.0-0.90.9-1.1-1.10.1
Condit. Reinf. active minus inactive responses0.10.20.5-0.1-0.00.3-0.4-0.30.40.30.4-0.4-0.3-0.4-0.40.4-0.40.5-0.4-0.70.4-0.4-0.40.50.5-0.50.40.40.6
Condit. Reinf. active-inactive response ratio0.50.61.60.2-0.50.7-0.6-0.60.70.70.7-0.7-0.6-0.7-0.70.7-0.70.9-0.7-1.30.6-0.7-0.70.70.7-0.80.70.71.2
Condit. Reinf. active responses0.00.00.3-0.30.3-0.1-0.10.00.10.00.1-0.1-0.00.00.00.0-0.10.1-0.1-0.60.2-0.1-0.10.10.1-0.20.10.10.5
Condit. Reinf. inactive responses0.20.20.4-0.40.6-0.60.40.5-0.4-0.5-0.40.40.50.70.7-0.50.5-0.60.5-0.1-0.40.40.6-0.5-0.50.5-0.6-0.60.1
Condit. Reinf. lever presses0.70.91.8-1.31.1-1.01.11.1-1.0-1.0-1.01.01.01.11.1-1.01.0-0.80.90.3-0.90.90.9-0.9-0.80.8-0.9-0.9-0.5
Condit. Reinf. lever reinforcers received0.00.10.2-0.40.4-0.30.20.2-0.1-0.2-0.20.10.20.30.3-0.20.2-0.10.2-0.4-0.10.10.2-0.2-0.10.1-0.1-0.20.3
Conditioned reinforcement - actives1.21.22.10.2-0.30.9-0.9-0.91.11.01.1-1.1-1.0-1.0-1.01.1-1.11.3-1.2-1.41.2-1.2-1.21.11.2-1.41.21.31.4
Conditioned reinforcement - inactives0.40.41.0-0.10.2-0.80.20.4-0.2-0.5-0.40.40.60.60.6-0.60.6-0.80.8-0.5-0.90.80.9-0.6-0.60.8-0.8-1.00.5
Conditioned locomotion3.94.77.50.7-0.91.7-1.9-1.92.12.02.0-2.1-2.1-2.3-2.32.2-2.32.7-2.4-1.92.6-2.3-2.42.32.6-2.72.32.61.9
Patch foraging indifference point 0 sec0.81.32.10.8-0.40.9-1.2-1.11.11.11.1-1.1-1.2-1.3-1.31.2-1.31.3-1.3-0.51.4-1.2-1.31.41.4-1.41.31.40.5
Patch foraging indifference point AUC0.10.20.4-0.60.4-0.30.30.5-0.3-0.4-0.40.40.40.50.5-0.40.5-0.40.4-0.1-0.40.40.4-0.4-0.50.4-0.4-0.40.3
Delay disc. indifference point, 0s delay0.91.01.6-0.60.7-1.00.90.9-0.9-1.0-0.91.01.01.01.0-1.01.0-1.01.10.8-0.91.01.1-1.1-1.11.1-1.3-1.2-0.7
Delay disc. indifference point, 16s delay0.30.30.50.4-0.50.5-0.6-0.40.50.50.4-0.4-0.5-0.6-0.60.5-0.50.7-0.60.40.5-0.5-0.60.50.5-0.50.70.6-0.4
Delay disc. indifference point, 2s delay0.30.31.1-0.40.4-0.70.30.5-0.5-0.5-0.60.60.50.30.3-0.60.4-0.40.41.1-0.40.50.5-0.4-0.40.4-0.8-0.5-1.0
Delay disc. indifference point, 24s delay0.60.51.1-1.01.0-0.90.70.8-0.8-0.8-0.80.80.70.60.6-0.70.7-0.40.60.9-0.70.80.5-0.7-0.70.6-0.3-0.5-1.0
Delay disc. indifference point, 4s delay3.94.17.5-1.71.6-2.11.82.0-2.0-2.0-2.12.22.01.91.9-2.12.0-1.91.92.7-1.92.01.9-1.9-2.02.0-2.0-1.9-2.7
Delay disc. indifference point, 8s delay0.10.20.4-0.70.6-0.50.30.4-0.3-0.4-0.40.40.40.30.3-0.40.4-0.20.30.4-0.30.40.3-0.4-0.40.2-0.1-0.2-0.5
Indifference point function ln k0.00.10.4-0.30.4-0.20.20.1-0.2-0.1-0.10.10.00.10.10.0-0.10.1-0.10.60.2-0.0-0.2-0.1-0.1-0.20.30.2-0.6
Indifference point function log k0.00.10.4-0.30.4-0.20.20.1-0.2-0.1-0.10.10.00.10.10.0-0.10.1-0.10.60.2-0.0-0.2-0.1-0.1-0.20.30.2-0.6
Patch foraging total patch changes 0 sec0.81.32.10.9-0.60.9-1.2-1.11.11.11.1-1.1-1.2-1.3-1.31.2-1.21.3-1.3-0.31.4-1.2-1.31.41.4-1.31.31.40.2
Patch foraging total patch changes 12 sec0.20.30.9-0.00.10.3-0.5-0.40.50.40.5-0.5-0.4-0.4-0.40.5-0.40.6-0.5-0.90.7-0.5-0.50.40.5-0.60.70.61.0
Patch foraging total patch changes 18 sec1.51.92.61.1-0.91.3-1.5-1.41.51.41.4-1.4-1.4-1.3-1.31.4-1.41.6-1.4-1.51.5-1.5-1.41.41.4-1.51.31.41.6
Patch foraging total patch changes 24 sec1.51.82.90.8-0.71.1-1.7-1.21.51.31.3-1.3-1.3-1.6-1.61.3-1.41.4-1.4-1.11.4-1.4-1.41.61.7-1.51.21.41.0
Patch foraging total patch changes 6 sec0.91.32.00.7-0.70.9-1.0-1.11.11.11.1-1.2-1.1-0.9-0.91.2-1.11.4-1.2-1.31.4-1.2-1.21.11.1-1.31.31.21.2
Patch foraging time to switch 0 sec0.10.10.50.10.00.3-0.3-0.30.30.30.3-0.3-0.3-0.4-0.40.3-0.30.3-0.3-0.70.3-0.4-0.30.30.4-0.40.30.40.6
Patch foraging water rate 0 sec0.61.02.11.2-1.41.0-1.0-1.00.91.00.9-0.9-1.0-1.1-1.10.9-1.01.0-1.00.41.1-1.0-1.01.11.1-0.91.11.0-0.4
Patch foraging water rate 12 sec0.20.21.80.4-0.1-0.40.40.2-0.5-0.3-0.40.40.30.40.4-0.30.3-0.30.31.3-0.20.40.3-0.4-0.40.5-0.3-0.4-1.3
Patch foraging water rate 18 sec0.50.71.9-0.20.4-0.90.70.7-0.8-0.8-0.80.80.80.50.5-0.80.7-0.90.81.3-0.80.80.9-0.6-0.70.9-0.9-0.9-1.4
Patch foraging water rate 24 sec0.60.82.11.2-1.40.9-0.8-1.00.80.90.9-0.9-0.9-0.9-0.90.9-1.01.0-0.9-0.21.0-1.0-0.90.90.9-0.90.90.90.2
Patch foraging water rate 6 sec0.00.00.1-0.0-0.3-0.10.00.10.0-0.1-0.10.10.20.00.0-0.20.2-0.30.2-0.0-0.30.20.3-0.1-0.10.3-0.3-0.30.2
Seeking ratio, delayed vs. immediate footshock0.40.41.51.1-1.20.9-0.5-0.80.50.70.8-0.7-0.7-0.5-0.50.7-0.50.2-0.5-0.80.7-0.6-0.50.40.3-0.40.60.50.7
Distance traveled before self-admin0.60.71.9-1.41.2-1.00.71.0-0.7-0.9-0.90.90.90.60.6-0.90.8-0.60.70.5-0.80.60.7-0.8-0.70.6-0.8-0.6-0.7
Distance traveled after self-admin0.91.02.20.3-0.10.8-0.9-0.80.90.90.8-0.9-1.0-0.9-0.91.1-1.11.5-1.2-0.31.4-1.2-1.31.01.0-1.51.31.40.1
Extensor digitorum longus weight0.10.52.51.6-0.60.3-0.5-0.80.20.60.4-0.4-0.6-0.4-0.40.6-0.70.8-0.61.40.7-0.6-0.60.50.5-0.40.60.6-1.3
Bone: elastic displacement0.10.20.40.1-0.40.4-0.3-0.30.40.40.4-0.4-0.4-0.5-0.50.4-0.50.6-0.5-0.20.4-0.4-0.50.50.5-0.50.30.50.1
Bone: elastic work0.00.00.6-0.10.1-0.00.00.0-0.1-0.0-0.10.1-0.00.00.00.1-0.10.3-0.10.60.1-0.1-0.20.10.1-0.20.20.2-0.7
Bone: endosteal estimation0.30.61.10.3-0.20.4-1.0-0.50.70.60.5-0.5-0.7-0.9-0.90.6-0.80.9-0.90.81.0-0.8-0.90.70.7-0.91.01.0-0.6
Bone: endosteal perimeter0.40.91.70.8-0.40.6-1.3-0.81.00.90.8-0.8-0.9-1.2-1.20.9-1.00.9-1.00.31.1-0.9-1.00.90.9-1.01.11.1-0.1
Epididymis fat weight0.00.10.80.4-0.2-0.0-0.1-0.1-0.10.1-0.00.0-0.10.00.00.1-0.10.3-0.10.90.0-0.0-0.1-0.1-0.2-0.0-0.20.1-0.8
Delta time in closed arm before/after self-admin0.10.10.20.4-0.2-0.20.3-0.0-0.3-0.1-0.10.10.10.50.5-0.00.1-0.10.20.3-0.10.20.1-0.3-0.40.3-0.2-0.2-0.4
Delta time in open arm before/after self-admin0.10.10.3-0.10.2-0.40.40.3-0.2-0.3-0.20.30.30.30.3-0.40.4-0.40.4-0.3-0.40.30.5-0.3-0.30.4-0.3-0.60.3
Diff in mean of infusions in LGA sessions0.60.71.5-0.70.7-0.70.60.7-0.6-0.7-0.70.70.80.90.9-0.80.9-1.00.9-0.1-1.00.90.9-0.9-1.00.9-1.2-1.00.2
Delay discount exponential model param0.50.52.00.8-0.70.9-0.5-0.70.70.70.8-0.8-0.7-0.5-0.50.7-0.60.4-0.6-1.40.6-0.6-0.50.60.6-0.50.50.51.4
Extinction: sum of active levers before priming1.21.21.7-1.01.1-1.21.31.1-1.3-1.1-1.11.11.01.21.2-1.01.0-1.01.01.3-0.81.00.9-1.0-1.01.0-0.9-0.9-1.3
Active lever presses in extinction session 60.10.10.30.1-0.00.3-0.4-0.20.50.30.3-0.3-0.3-0.5-0.50.3-0.30.3-0.3-0.60.3-0.3-0.40.30.4-0.40.30.40.4
Bone: final force0.20.30.50.5-0.30.4-0.7-0.50.60.50.5-0.5-0.5-0.6-0.60.5-0.60.6-0.6-0.00.6-0.6-0.60.40.4-0.60.60.60.2
Bone: final moment0.20.40.70.5-0.40.5-0.8-0.60.60.60.6-0.6-0.6-0.7-0.70.6-0.70.7-0.70.10.7-0.7-0.70.50.5-0.70.70.70.1
Food consumed during 24 hour testing period1.51.83.3-1.51.8-1.51.41.4-1.4-1.4-1.41.31.31.31.3-1.31.3-1.41.30.9-1.21.31.3-1.3-1.21.2-1.2-1.2-0.9
Glucose0.50.81.81.4-1.21.1-0.9-0.90.80.90.8-0.8-0.9-0.7-0.70.9-0.90.9-0.90.31.0-0.9-0.90.80.8-0.80.80.9-0.4
Heart weight1.31.93.71.6-1.91.5-1.8-1.41.51.41.3-1.3-1.4-1.5-1.51.2-1.41.2-1.4-0.01.2-1.4-1.31.51.5-1.21.21.30.1
Delay discount hyperbolic model param0.80.82.40.9-0.81.1-0.7-0.90.90.91.0-1.0-0.9-0.7-0.70.9-0.80.6-0.8-1.50.8-0.8-0.70.80.8-0.80.80.71.5
Intermittent access intake day 1-15 change2.32.33.31.0-1.41.5-1.7-1.41.81.41.4-1.4-1.5-1.7-1.71.4-1.61.7-1.6-0.91.5-1.6-1.61.61.7-1.71.41.60.8
Intermittent access intake escalation2.32.33.40.7-1.21.5-1.7-1.31.81.41.4-1.4-1.4-1.7-1.71.4-1.61.7-1.6-1.01.6-1.6-1.61.61.7-1.81.51.70.9
Intermittent access intake escalation 21.71.72.70.8-1.31.5-1.5-1.21.61.31.2-1.2-1.3-1.5-1.51.2-1.41.5-1.4-0.81.3-1.5-1.41.31.3-1.51.31.40.7
Intermitt. access day 1 inactive lever presses0.20.20.70.3-0.1-0.20.00.2-0.1-0.3-0.20.20.40.60.6-0.40.5-0.60.6-0.5-0.80.50.7-0.6-0.60.7-0.6-0.80.4
Intermitt. access day 15 inactive lever presses0.70.84.80.9-1.00.9-0.8-0.81.10.80.9-0.9-0.7-0.4-0.40.6-0.50.2-0.5-2.20.3-0.6-0.40.60.5-0.40.50.32.0
Intermitt. access escalation Index1.71.53.20.1-0.21.0-1.0-0.91.11.01.0-1.0-1.2-1.3-1.31.3-1.21.5-1.4-0.41.8-1.4-1.61.41.3-1.71.71.80.5
Intermittent access day 1 total infusions0.30.30.8-0.50.8-0.70.80.5-0.8-0.5-0.50.50.50.90.9-0.40.6-0.50.60.1-0.40.60.5-0.8-0.80.5-0.2-0.5-0.2
Intermittent access day 15 total infusions0.20.20.5-0.20.10.3-0.3-0.30.50.30.3-0.4-0.4-0.4-0.40.4-0.40.6-0.5-0.50.6-0.5-0.50.30.4-0.70.60.60.4
Intermittent access terminal intake (last 3 days)0.20.20.70.1-0.10.4-0.4-0.40.50.40.4-0.5-0.4-0.3-0.30.4-0.40.5-0.4-0.80.5-0.5-0.40.30.4-0.50.50.50.7
Intermittent access total infusions0.00.00.1-0.10.1-0.10.1-0.0-0.00.00.0-0.0-0.00.10.10.1-0.00.1-0.1-0.10.1-0.0-0.1-0.00.0-0.10.20.1-0.1
Intermittent access day 1 locomotion0.20.20.9-0.80.9-0.60.60.5-0.6-0.5-0.50.50.50.50.5-0.40.4-0.40.40.0-0.40.40.4-0.5-0.30.3-0.3-0.4-0.1
Intermittent access day 15 total locomotion0.30.30.5-0.10.10.4-0.7-0.40.70.40.5-0.5-0.5-0.7-0.70.5-0.50.6-0.6-0.70.6-0.6-0.60.50.7-0.70.60.60.5
Intermittent access total locomotion0.50.61.2-0.20.10.5-0.7-0.50.80.60.6-0.7-0.7-0.9-0.90.7-0.81.0-0.9-0.80.9-0.8-0.90.81.0-1.11.01.00.6
Intermittent access standard deviation1.92.03.60.8-1.51.6-1.9-1.21.91.31.3-1.3-1.3-1.8-1.81.2-1.41.3-1.4-0.91.3-1.5-1.41.51.6-1.51.41.40.7
Left kidney weight0.30.89.80.0-0.1-0.4-0.00.4-0.5-0.4-0.70.70.30.10.1-0.50.3-0.30.13.1-0.10.30.1-0.2-0.20.3-0.00.0-3.0
Right kidney weight0.30.92.91.0-1.10.6-1.0-0.70.60.70.5-0.5-0.8-0.9-0.90.7-0.91.0-1.01.71.0-0.9-1.00.80.9-0.81.01.1-1.6
Cocaine induced anxiety0.10.10.10.2-0.30.2-0.3-0.20.30.20.2-0.2-0.2-0.4-0.40.2-0.20.2-0.30.10.2-0.3-0.20.30.3-0.20.30.2-0.1
Post-drug Anxiety0.40.40.8-0.50.4-0.50.60.6-0.5-0.6-0.50.50.70.60.6-0.70.7-0.80.8-0.4-0.80.70.8-0.7-0.80.8-0.8-0.90.5
Baseline Anxiety0.20.22.40.2-0.20.20.0-0.10.10.10.2-0.2-0.00.10.10.00.1-0.30.2-1.4-0.20.10.3-0.2-0.20.2-0.3-0.41.6
Tail length12.337.452.2-7.26.5-6.55.96.6-6.3-6.5-6.76.66.25.85.8-6.26.0-5.65.77.2-5.55.85.4-5.7-5.65.4-5.3-5.1-7.1
Length with tail8.229.960.0-5.75.4-5.65.05.8-5.6-5.7-6.06.05.45.15.1-5.55.2-4.94.97.7-4.75.14.8-5.1-5.04.8-4.7-4.5-7.6
Length without tail0.40.95.7-0.00.4-0.70.50.6-0.8-0.7-0.90.90.70.90.9-0.80.7-0.60.62.4-0.50.70.6-0.9-0.90.8-0.8-0.7-2.2
Times rat made contact with spout0.10.10.5-0.40.7-0.30.40.2-0.2-0.2-0.20.20.20.20.2-0.20.2-0.40.2-0.4-0.20.20.2-0.1-0.10.2-0.2-0.20.5
Lifetime Intake0.00.00.2-0.30.4-0.30.30.2-0.2-0.2-0.10.10.10.20.2-0.10.1-0.10.1-0.1-0.00.20.1-0.2-0.10.00.1-0.0-0.1
Liver weight, left0.81.31.6-1.31.0-1.21.01.2-1.0-1.2-1.21.21.21.01.0-1.31.2-1.21.20.8-1.31.21.2-1.3-1.21.2-1.2-1.1-1.0
Liver weight, right1.32.25.9-1.11.0-1.21.11.5-1.3-1.5-1.61.61.41.31.3-1.51.5-1.51.42.3-1.31.41.3-1.6-1.51.5-1.4-1.3-2.4
Locomotor activity0.71.12.80.6-0.40.9-0.9-0.91.01.01.0-1.1-1.0-1.1-1.11.0-0.90.8-0.9-1.71.1-1.0-0.91.01.1-1.01.01.01.6
Locomotor testing distance1.32.27.00.9-0.71.2-1.2-1.41.51.41.5-1.6-1.4-1.4-1.41.5-1.31.2-1.3-2.61.4-1.4-1.31.41.4-1.51.41.32.6
Locomotor testing rearing0.20.33.00.10.10.3-0.3-0.30.50.30.5-0.5-0.2-0.4-0.40.3-0.20.0-0.1-1.70.1-0.3-0.10.20.2-0.20.10.01.7
Locomotion in novel chamber0.60.71.30.20.2-0.71.00.6-0.9-0.7-0.70.70.71.11.1-0.80.9-1.11.00.4-1.00.91.0-0.9-1.01.2-1.1-1.1-0.5
Locomotion in novel chamber post-restriction1.82.23.41.6-1.41.3-1.2-1.61.41.61.6-1.6-1.5-1.2-1.21.6-1.51.5-1.4-1.81.5-1.4-1.41.41.3-1.51.51.41.8
Fecal boli incidents, locomotor time 12.93.25.12.1-2.32.1-1.9-1.91.91.91.9-1.9-1.8-1.7-1.71.8-1.81.6-1.8-1.21.7-1.8-1.71.81.8-1.61.81.61.2
Change in fecal boli incidents, locomotor task2.42.33.1-1.21.5-1.71.81.4-1.7-1.5-1.51.51.51.61.6-1.51.5-1.41.51.2-1.51.61.5-1.6-1.61.5-1.4-1.5-1.3
Time >=10cm from walls, locomotor time 10.20.20.5-0.40.7-0.40.60.3-0.4-0.4-0.30.30.40.50.5-0.30.5-0.60.5-0.5-0.40.50.4-0.5-0.50.4-0.3-0.50.5
Bouts of movement, locomotor time 10.00.10.20.4-0.40.4-0.1-0.20.10.20.2-0.2-0.2-0.2-0.20.2-0.20.0-0.20.30.0-0.1-0.20.20.2-0.10.40.2-0.3
Total resting periods, locomotor time 10.10.20.60.7-0.80.6-0.3-0.40.20.40.3-0.3-0.4-0.3-0.30.3-0.30.2-0.40.50.2-0.3-0.40.30.3-0.20.60.3-0.5
Rest time, locomotor task time 10.20.20.40.5-0.60.5-0.5-0.40.50.40.4-0.4-0.4-0.4-0.40.4-0.40.4-0.5-0.20.5-0.5-0.50.40.4-0.50.70.5-0.3
Distance moved, locomotor task time 11.11.21.8-1.31.3-1.11.21.2-1.2-1.2-1.11.11.10.90.9-1.11.1-1.11.11.0-1.11.21.1-1.0-1.01.0-1.0-1.0-0.7
Vertical activity count, locomotor time 10.30.30.7-0.60.9-0.70.80.5-0.8-0.5-0.50.50.50.40.4-0.40.5-0.30.50.4-0.50.60.5-0.4-0.40.4-0.4-0.4-0.1
Time >=10cm from walls, locomotor time 20.50.60.9-0.60.7-0.80.90.7-0.9-0.7-0.70.70.70.80.8-0.70.8-0.90.80.2-0.80.80.8-0.8-0.80.8-0.8-0.8-0.2
Bouts of movement, locomotor time 20.10.10.30.4-0.40.4-0.4-0.30.30.40.4-0.4-0.3-0.3-0.30.3-0.30.4-0.3-0.20.1-0.3-0.30.30.3-0.30.40.30.5
Total resting periods, locomotor time 20.10.20.30.5-0.50.4-0.4-0.40.40.40.4-0.4-0.4-0.3-0.30.4-0.40.5-0.4-0.40.2-0.3-0.30.30.3-0.30.50.30.6
Rest time, locomotor task time 20.91.11.7-0.50.6-0.91.10.9-1.0-0.9-0.90.91.01.31.3-1.01.1-1.31.2-0.1-1.11.11.2-1.2-1.21.3-0.9-1.3-0.1
Distance moved, locomotor task time 20.30.32.5-0.50.4-0.50.50.5-0.6-0.5-0.60.60.40.10.1-0.40.3-0.20.21.6-0.20.30.2-0.1-0.10.2-0.4-0.1-1.5
Vertical activity count, locomotor time 20.20.21.5-0.10.3-0.20.1-0.0-0.20.0-0.10.1-0.1-0.4-0.40.2-0.30.7-0.31.20.3-0.2-0.40.40.4-0.40.30.5-1.2
Light reinforcement 10.50.94.00.3-0.50.9-0.8-0.80.90.91.0-1.0-0.8-0.6-0.60.9-0.80.7-0.8-1.90.8-0.9-0.80.80.9-0.90.70.82.0
Light reinforcement 20.10.10.4-0.40.30.1-0.1-0.10.20.10.1-0.2-0.1-0.1-0.10.2-0.10.2-0.2-0.60.3-0.2-0.20.20.2-0.30.30.30.6
Bone: marrow area0.20.40.80.1-0.10.3-0.9-0.40.60.40.3-0.3-0.5-0.7-0.70.5-0.60.7-0.70.80.8-0.6-0.80.60.6-0.80.90.9-0.6
Bone: maximum diameter0.40.71.40.6-0.40.5-1.2-0.81.00.80.8-0.8-0.8-1.0-1.00.8-0.90.9-0.9-0.11.0-0.9-0.90.80.8-1.00.91.00.3
Bone: maximum force0.50.81.30.9-0.60.7-1.1-0.90.80.90.8-0.8-0.9-0.9-0.90.9-1.01.0-1.00.41.0-1.0-1.10.80.8-1.01.11.1-0.2
Bone: maximum moment0.50.91.40.9-0.60.8-1.1-0.90.90.90.8-0.8-1.0-1.0-1.00.9-1.01.1-1.10.61.1-1.0-1.10.90.9-1.01.11.2-0.4
Mean time between licks in bursts0.10.20.91.0-0.50.4-0.2-0.60.30.50.5-0.4-0.5-0.3-0.30.5-0.40.4-0.4-0.10.3-0.2-0.30.40.4-0.20.40.30.1
Mean num. licks in bursts0.00.00.1-0.20.3-0.20.20.2-0.2-0.2-0.20.20.20.10.1-0.20.2-0.20.20.4-0.30.20.2-0.1-0.20.2-0.2-0.2-0.3
Cd content in liver0.60.61.1-0.10.5-0.60.80.6-0.7-0.7-0.60.70.70.90.9-0.70.8-1.00.90.5-1.00.90.9-0.8-0.91.0-0.8-1.0-0.3
Co content in liver0.00.10.50.4-0.70.4-0.2-0.20.10.20.1-0.1-0.2-0.1-0.10.1-0.10.1-0.10.30.1-0.1-0.10.20.1-0.00.20.1-0.3
Cu content in liver2.12.64.8-2.22.2-1.81.41.8-1.4-1.7-1.61.61.71.71.7-1.61.6-1.51.60.6-1.51.51.5-1.7-1.71.4-1.5-1.5-0.7
Fe content in liver1.61.93.3-1.11.5-1.31.11.4-1.3-1.4-1.41.41.31.31.3-1.41.3-1.21.31.8-1.31.31.3-1.4-1.41.3-1.3-1.2-1.8
K content in liver0.10.10.30.1-0.30.4-0.6-0.20.50.30.3-0.3-0.3-0.4-0.40.3-0.30.2-0.40.00.3-0.4-0.40.40.4-0.40.30.4-0.0
Mg content in liver0.70.71.0-0.70.8-0.90.60.8-0.6-0.8-0.80.80.80.90.9-0.90.8-1.00.90.4-0.90.90.9-1.0-1.00.9-0.9-0.9-0.2
Mn content in liver2.42.74.9-2.21.9-1.71.71.8-1.5-1.7-1.61.61.71.71.7-1.71.7-1.81.7-0.0-1.71.61.7-1.6-1.61.5-1.7-1.70.0
Na content in liver0.90.91.80.1-0.40.8-1.1-0.71.10.80.9-0.9-0.9-1.3-1.30.9-0.91.0-1.0-1.40.9-1.0-0.91.01.1-1.10.81.01.2
Rb content in liver0.10.21.30.2-0.0-0.0-0.1-0.00.2-0.00.1-0.10.10.60.6-0.10.2-0.20.3-1.1-0.20.20.3-0.4-0.50.3-0.3-0.41.1
Se content in liver0.20.20.70.8-0.80.7-0.7-0.50.70.50.5-0.5-0.5-0.6-0.60.4-0.40.3-0.4-0.30.3-0.4-0.40.40.4-0.30.30.30.3
Sr content in liver2.01.92.8-1.41.7-1.61.61.4-1.6-1.4-1.51.51.41.11.1-1.41.3-1.21.31.6-1.31.41.3-1.2-1.11.3-1.3-1.2-1.6
Zn content in liver0.10.10.70.4-0.30.2-0.2-0.30.30.30.3-0.3-0.2-0.3-0.30.2-0.30.1-0.2-0.60.1-0.2-0.10.30.3-0.1-0.00.10.8
Bone: minimum diameter0.10.11.60.20.2-0.0-0.4-0.10.10.10.00.0-0.2-0.3-0.30.1-0.20.3-0.31.30.3-0.2-0.30.20.2-0.30.30.4-1.0
Time in familiar zone, hab. session 10.50.50.8-0.30.3-0.40.80.5-0.5-0.5-0.40.40.60.90.9-0.50.7-0.90.8-0.6-0.80.80.8-0.8-0.90.8-0.7-0.90.7
Time in novel zone, hab. session 13.03.03.51.6-1.71.7-1.8-1.71.71.71.7-1.7-1.7-1.9-1.91.7-1.81.8-1.8-1.01.8-1.8-1.81.91.9-1.81.81.81.0
Total zone transitions, hab. session 16.28.79.3-2.72.8-3.03.03.0-3.0-3.0-3.03.03.03.03.0-3.03.0-2.93.02.3-3.03.03.0-3.1-3.03.0-3.0-3.0-2.3
Total locomotion distance, hab. session 12.53.64.2-2.01.7-1.91.92.0-1.8-2.0-1.91.92.02.02.0-2.02.0-1.92.01.1-2.02.02.0-2.0-2.01.9-1.8-1.9-1.2
Locomotion velocity, hab. session 13.55.05.5-2.32.1-2.32.22.3-2.2-2.3-2.32.32.32.22.2-2.32.3-2.22.21.8-2.32.32.2-2.3-2.32.2-2.2-2.2-1.9
Time in familiar zone, hab. session 20.60.61.81.1-1.00.9-0.6-0.80.80.80.9-0.9-0.7-0.5-0.50.7-0.70.6-0.6-1.30.4-0.6-0.50.60.6-0.50.40.41.3
Time in novel zone, hab. session 20.10.10.6-0.30.3-0.40.20.3-0.3-0.3-0.40.30.30.20.2-0.30.2-0.20.20.8-0.10.20.2-0.2-0.20.20.0-0.1-0.7
Total zone transitions, hab. session 21.82.33.9-1.92.0-1.71.51.7-1.5-1.6-1.61.61.61.51.5-1.61.5-1.41.50.8-1.61.51.5-1.5-1.51.4-1.5-1.4-0.8
Total locomotion distance, hab. session 20.00.00.4-0.60.3-0.20.00.3-0.1-0.2-0.20.20.20.10.1-0.20.1-0.00.10.1-0.20.10.1-0.2-0.10.0-0.1-0.0-0.1
Locomotion velocity, hab. session 20.10.10.6-0.80.5-0.30.10.4-0.2-0.4-0.40.40.30.20.2-0.30.3-0.10.20.4-0.30.20.2-0.3-0.20.1-0.2-0.1-0.4
Novel to familiar place preference ratio1.01.12.9-0.50.9-0.91.00.9-1.2-1.0-1.11.10.91.01.0-1.01.0-1.01.01.7-0.81.00.9-1.0-1.11.1-0.8-0.9-1.6
Novelty place preference1.21.22.8-0.61.0-0.91.11.0-1.3-1.1-1.11.11.01.11.1-1.11.1-1.11.11.7-0.91.11.0-1.1-1.21.2-0.9-1.0-1.6
Time in novel zone, NPP test0.90.91.9-0.40.8-0.81.00.8-1.1-0.9-0.91.00.91.01.0-0.91.0-1.00.91.4-0.81.00.9-1.0-1.11.0-0.7-0.9-1.3
Total zone transitions, NPP test3.44.86.7-2.62.5-2.52.22.4-2.2-2.3-2.32.32.32.12.1-2.32.2-2.02.21.5-2.32.12.2-2.2-2.12.0-2.3-2.1-1.6
Total locomotion distance, NPP test0.81.01.7-1.31.2-1.20.91.1-0.9-1.1-1.11.11.11.01.0-1.11.0-0.91.00.6-1.10.91.0-1.0-1.00.9-1.1-1.0-0.6
Locomotion velocity, NPP test1.31.92.9-1.71.5-1.51.21.5-1.3-1.5-1.51.51.41.31.3-1.51.3-1.21.31.2-1.41.31.3-1.4-1.31.2-1.4-1.3-1.3
Intraocular pressure1.62.24.2-1.92.1-1.51.41.6-1.5-1.6-1.61.61.51.61.6-1.41.5-1.31.31.5-1.21.41.2-1.4-1.51.2-0.9-1.1-1.8
Delta distance traveled before/after self-admin2.32.53.91.5-1.21.5-1.3-1.71.31.61.6-1.6-1.7-1.3-1.31.8-1.71.9-1.7-1.02.0-1.7-1.81.51.4-1.81.91.81.1
Delta ambulatory time before/after self-admin2.72.94.11.9-1.51.7-1.5-1.91.51.81.8-1.8-1.9-1.4-1.41.9-1.81.9-1.8-0.92.0-1.8-1.91.61.6-1.81.91.91.0
Parametrial fat weight0.00.00.2-0.40.5-0.1-0.2-0.00.10.10.1-0.1-0.1-0.1-0.10.2-0.10.2-0.2-0.20.2-0.1-0.20.1-0.0-0.30.50.30.4
Pavlov. Cond. lever latency1.21.52.41.1-1.51.5-1.3-1.21.11.21.1-1.1-1.3-1.1-1.11.2-1.21.3-1.30.11.5-1.3-1.41.21.2-1.31.51.4-0.2
Pavlov. Cond. magazine entry latency0.10.11.3-0.60.4-0.20.10.10.0-0.10.0-0.00.10.00.0-0.00.1-0.10.1-1.0-0.10.00.1-0.0-0.0-0.10.1-0.01.1
Pavlov. Cond. change in total contacts2.02.23.0-1.71.7-1.61.61.5-1.4-1.5-1.41.31.51.51.5-1.41.5-1.61.6-0.2-1.61.51.6-1.6-1.61.4-1.5-1.60.3
Pavlov. Cond. index score0.40.61.1-1.01.0-0.90.80.7-0.6-0.7-0.60.60.70.60.6-0.60.7-0.70.8-0.8-0.90.70.8-0.7-0.60.6-0.8-0.80.9
Pavlov. Cond. latency score0.50.61.2-1.01.1-1.00.90.8-0.7-0.8-0.70.70.80.70.7-0.70.8-0.80.8-0.6-1.00.80.9-0.7-0.70.7-0.9-0.90.7
Pavlov. Cond. lever contacts1.72.03.1-1.51.8-1.71.51.4-1.3-1.4-1.31.31.51.31.3-1.41.4-1.41.5-0.1-1.71.51.5-1.4-1.31.4-1.6-1.50.2
Pavlov. Cond. magazine entry number0.30.42.50.9-0.70.6-0.5-0.40.20.40.2-0.2-0.4-0.3-0.30.3-0.40.5-0.41.40.5-0.4-0.50.50.5-0.30.40.5-1.6
Pavlov. Cond. intertrial magazine entries0.50.71.1-0.50.4-0.60.70.7-0.7-0.8-0.80.80.81.01.0-0.80.8-0.80.80.9-0.70.70.8-0.9-1.00.9-0.7-0.8-1.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-1.01.1-0.90.80.7-0.6-0.6-0.50.50.70.60.6-0.60.6-0.70.7-0.8-0.80.70.7-0.6-0.60.5-0.7-0.71.0
Pavlov. Cond. response bias0.50.61.3-1.11.0-0.90.80.7-0.6-0.7-0.60.50.70.70.7-0.60.7-0.70.8-1.0-0.90.70.8-0.7-0.80.6-0.8-0.81.1
Pavlov. Cond. lever latency0.70.91.8-0.81.3-1.10.90.9-1.0-0.9-1.01.00.90.80.8-0.90.9-0.90.91.0-1.01.00.9-1.0-1.00.9-0.8-0.9-0.8
Pavlov. Cond. magazine entry latency0.50.61.2-0.80.5-0.60.90.8-0.9-0.8-0.80.80.80.70.7-0.80.7-0.80.71.0-0.70.70.7-0.5-0.40.7-0.8-0.6-1.1
Pavlov. Cond. change in total contacts0.20.30.6-0.2-0.50.5-0.5-0.40.50.40.4-0.5-0.4-0.4-0.40.5-0.50.5-0.5-0.70.7-0.6-0.60.60.7-0.70.60.60.5
Pavlov. Cond. index score0.20.30.60.2-0.70.7-0.5-0.40.40.50.5-0.5-0.5-0.5-0.50.5-0.50.5-0.6-0.20.6-0.7-0.60.70.8-0.60.50.70.1
Pavlov. Cond. latency score0.10.10.3-0.1-0.50.4-0.3-0.20.20.20.2-0.2-0.3-0.3-0.30.3-0.30.3-0.40.10.4-0.4-0.40.50.6-0.40.30.5-0.3
Pavlov. Cond. lever contacts0.50.71.40.7-1.21.0-0.8-0.80.90.90.9-0.9-0.8-0.8-0.80.8-0.80.8-0.8-1.00.9-0.9-0.80.91.0-0.80.80.80.8
Pavlov. Cond. magazine entry number0.00.00.30.20.2-0.1-0.1-0.10.20.10.1-0.1-0.0-0.1-0.10.00.0-0.00.0-0.4-0.10.10.1-0.2-0.30.1-0.1-0.10.6
Pavlov. Cond. intertrial magazine entries1.72.23.4-1.21.4-1.51.41.4-1.3-1.5-1.41.41.51.61.6-1.51.5-1.51.60.9-1.51.51.6-1.8-1.81.6-1.6-1.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.2-0.80.7-0.5-0.50.50.50.5-0.5-0.6-0.6-0.60.6-0.60.6-0.7-0.20.7-0.7-0.70.80.9-0.70.60.70.0
Pavlov. Cond. response bias0.50.71.30.6-1.11.0-0.8-0.80.80.80.8-0.8-0.8-0.7-0.70.8-0.80.8-0.8-0.80.9-0.9-0.80.91.0-0.80.80.80.6
Time in closed arm before self-admin1.21.42.71.6-1.61.3-1.4-1.31.31.31.3-1.2-1.2-1.3-1.31.1-1.21.0-1.1-0.90.9-1.1-0.91.21.3-0.90.70.81.0
Time in closed arm after self-admin0.80.83.92.0-1.70.9-0.9-1.20.81.01.0-0.9-0.9-0.6-0.60.9-0.90.7-0.8-0.10.6-0.7-0.70.90.8-0.50.50.50.1
Time in open arm before self-admin0.20.30.9-0.60.8-0.71.00.4-0.8-0.5-0.50.40.40.60.6-0.30.4-0.10.40.1-0.00.50.3-0.7-0.80.2-0.2-0.2-0.2
Time in open arm after self-admin0.40.51.1-0.71.0-0.91.00.6-0.8-0.6-0.60.50.60.80.8-0.50.7-0.60.7-0.5-0.50.70.7-0.8-0.90.6-0.5-0.70.4
Bone: periosteal estimation0.30.71.30.7-0.30.5-1.1-0.70.80.70.7-0.7-0.8-1.0-1.00.8-0.90.9-0.90.50.9-0.8-0.90.70.7-0.91.01.0-0.3
Bone: periosteal perimeter0.30.61.21.1-0.40.6-1.0-0.80.80.80.7-0.7-0.8-1.0-1.00.7-0.80.7-0.80.50.7-0.7-0.80.80.7-0.70.70.8-0.3
Bone: post-yield work0.10.20.70.8-0.50.5-0.5-0.50.30.40.4-0.4-0.5-0.1-0.10.4-0.30.4-0.40.50.4-0.4-0.50.30.2-0.30.70.4-0.4
Progressive ratio test 1 active lever presses0.20.20.8-0.70.8-0.70.90.4-0.8-0.4-0.50.40.40.50.5-0.20.3-0.10.30.4-0.10.40.2-0.4-0.30.2-0.1-0.1-0.6
Progressive ratio test 1 breakpoint0.40.41.2-0.80.9-0.81.10.6-1.0-0.6-0.70.60.60.70.7-0.50.6-0.40.50.6-0.40.70.4-0.6-0.60.5-0.3-0.4-0.8
Progressive ratio test 1 inactive lever presses0.10.10.40.5-0.30.1-0.1-0.30.20.30.3-0.3-0.30.10.10.3-0.20.2-0.2-0.60.1-0.1-0.20.20.2-0.10.30.10.4
Progressive ratio test 2 active lever presses0.10.10.6-0.70.8-0.50.50.3-0.3-0.3-0.30.20.30.50.5-0.20.2-0.20.2-0.4-0.20.30.2-0.3-0.30.1-0.1-0.20.3
Progressive ratio test 2 breakpoint0.10.10.4-0.50.6-0.40.40.2-0.2-0.2-0.10.10.10.30.3-0.00.1-0.10.1-0.4-0.10.20.1-0.2-0.1-0.00.0-0.00.3
Progressive ratio test 2 inactive lever presses0.10.10.20.2-0.1-0.20.00.1-0.0-0.1-0.10.10.20.40.4-0.20.2-0.40.3-0.5-0.40.30.4-0.3-0.40.4-0.3-0.50.4
Incentive Sensitization - Responses0.10.10.40.10.00.1-0.3-0.20.40.20.2-0.2-0.2-0.2-0.20.2-0.20.1-0.2-0.60.1-0.2-0.10.20.3-0.20.10.10.6
Incentive Sensitization - Breakpoint0.20.20.40.2-0.20.3-0.6-0.40.60.40.4-0.4-0.4-0.4-0.40.4-0.40.3-0.4-0.60.3-0.4-0.40.40.5-0.40.40.40.6
Sum of active levers in priming session hrs 5-63.73.65.2-2.32.3-2.01.92.1-1.8-2.0-2.02.02.01.81.8-2.02.0-1.91.91.1-1.91.91.9-1.8-1.71.8-2.1-1.8-1.1
Progressive ratio0.20.21.00.6-0.6-0.1-0.20.20.0-0.2-0.20.30.30.10.1-0.50.3-0.60.40.4-0.70.30.6-0.3-0.20.8-1.0-0.7-0.4
Food seeking constrained by brief footshock0.50.61.00.20.10.8-1.0-0.61.00.70.7-0.7-0.8-1.0-1.00.8-0.80.9-0.9-0.50.9-0.9-0.90.70.7-1.00.91.00.6
Seeking ratio, punishment vs. effort0.20.31.4-0.91.00.10.2-0.10.00.20.2-0.2-0.3-0.1-0.10.5-0.40.7-0.5-0.30.7-0.3-0.70.20.2-0.91.20.90.4
Retroperitoneal fat weight0.31.11.90.6-1.01.0-1.4-0.81.00.80.7-0.7-0.9-1.0-1.00.9-1.01.2-1.21.21.2-1.1-1.20.90.9-1.21.11.3-1.0
Reaction time number correct0.10.10.30.4-0.3-0.20.20.1-0.2-0.2-0.20.20.30.20.2-0.30.2-0.50.30.4-0.50.30.5-0.2-0.30.5-0.5-0.5-0.4
Reaction time mean minus median0.60.83.2-1.71.8-0.91.10.9-0.9-0.8-0.80.70.81.11.1-0.60.8-0.60.7-0.6-0.30.70.6-1.0-0.90.4-0.3-0.50.6
Reaction time mean minus median AUC0.81.13.7-1.91.9-1.01.21.0-1.0-1.0-0.80.80.91.31.3-0.71.0-0.80.9-1.0-0.50.80.8-1.1-1.00.5-0.5-0.70.9
Reaction time num false alarms0.20.30.9-0.90.7-0.80.70.6-0.7-0.6-0.60.50.60.40.4-0.50.4-0.40.50.2-0.50.50.5-0.4-0.40.4-0.6-0.50.1
Reaction time num false alarms AUC0.30.41.2-1.10.8-0.90.70.8-0.8-0.7-0.70.70.70.50.5-0.70.6-0.60.60.4-0.60.60.6-0.5-0.40.4-0.7-0.6-0.1
Reaction time trials correct on left0.10.10.30.4-0.3-0.20.20.1-0.2-0.2-0.20.20.30.20.2-0.30.2-0.50.30.4-0.50.30.5-0.2-0.30.5-0.5-0.5-0.4
Reaction time trials on left0.10.10.30.3-0.2-0.20.20.1-0.3-0.2-0.20.30.30.20.2-0.30.2-0.50.40.4-0.50.30.5-0.3-0.30.5-0.5-0.5-0.4
Reaction time mean0.20.32.0-1.00.9-0.10.40.1-0.1-0.00.1-0.1-0.00.40.40.20.00.2-0.1-1.30.5-0.1-0.2-0.2-0.2-0.40.60.31.4
Reaction time mean AUC0.20.31.7-1.11.0-0.30.50.2-0.2-0.1-0.0-0.00.00.40.40.10.10.10.0-1.30.40.0-0.2-0.2-0.2-0.40.50.21.3
Median of all reaction times0.30.42.9-0.60.20.4-0.1-0.30.40.40.5-0.5-0.4-0.2-0.20.6-0.40.5-0.5-1.60.7-0.5-0.60.30.3-0.80.80.61.7
Reaction time omissions0.10.21.5-1.21.0-0.20.50.4-0.4-0.3-0.30.20.20.50.5-0.10.3-0.00.1-0.40.20.1-0.0-0.3-0.3-0.20.30.10.4
Reaction time false alarm rate0.10.11.1-1.00.7-0.50.40.5-0.4-0.4-0.40.30.30.20.2-0.30.2-0.10.20.1-0.10.30.2-0.2-0.1-0.0-0.2-0.10.2
Reaction time premature initiation rate0.40.51.0-0.70.6-0.91.00.7-0.9-0.7-0.70.70.70.80.8-0.60.7-0.60.70.5-0.50.70.6-0.7-0.70.6-0.6-0.6-0.7
Reaction time premature initiations0.60.91.4-0.70.7-1.11.20.9-1.1-0.9-0.90.90.91.01.0-0.90.9-0.90.90.8-0.80.90.9-0.9-0.90.9-1.0-0.9-0.9
Std. dev. reaction times0.40.52.6-1.61.6-0.80.90.8-0.7-0.7-0.60.60.60.90.9-0.40.6-0.40.5-0.5-0.10.50.4-0.8-0.70.1-0.1-0.30.5
Reaction time trials completed0.10.10.30.3-0.2-0.20.20.1-0.3-0.2-0.20.30.30.20.2-0.30.2-0.50.40.4-0.50.30.5-0.3-0.30.5-0.5-0.5-0.4
Reaction time trials AUC0.10.10.40.3-0.1-0.30.20.1-0.3-0.2-0.20.30.30.20.2-0.40.3-0.50.40.4-0.50.30.5-0.3-0.40.6-0.6-0.6-0.3
Run reversals in cocaine runway, females0.40.41.8-0.70.4-0.70.70.6-0.7-0.6-0.60.60.50.50.5-0.40.4-0.20.31.4-0.30.50.2-0.4-0.40.3-0.3-0.2-1.4
Run reversals in cocaine runway, males1.41.45.51.4-1.40.8-0.8-1.31.01.21.3-1.3-1.1-0.8-0.81.2-1.00.9-0.9-2.30.9-0.9-0.80.90.9-0.80.70.62.4
Latency to leave start box in cocaine runway2.83.06.72.6-2.32.0-2.0-2.01.91.91.8-1.8-1.8-1.7-1.71.8-1.81.7-1.7-0.61.5-1.7-1.61.61.5-1.41.51.50.7
Latency to leave start box in cocaine runway, F4.44.89.33.0-2.82.4-2.4-2.52.32.32.3-2.2-2.3-2.0-2.02.2-2.32.3-2.2-0.82.1-2.2-2.22.11.9-2.02.12.00.8
Latency to leave start box in cocaine runway, M0.50.51.10.6-0.41.0-1.1-0.71.00.70.7-0.7-0.7-0.8-0.80.6-0.60.5-0.7-0.40.4-0.6-0.70.70.7-0.60.60.70.5
Std. dev. time between licks in bursts1.11.41.70.7-1.01.1-1.2-1.11.21.11.1-1.2-1.1-1.3-1.31.2-1.21.2-1.2-0.91.2-1.2-1.21.21.2-1.31.31.31.0
Total sessions with >9 infusions0.30.30.8-0.60.50.2-0.4-0.20.50.30.3-0.4-0.4-0.4-0.40.5-0.50.8-0.6-0.50.8-0.5-0.70.40.4-0.90.90.90.2
Short access day 1 total inactive lever presses2.93.35.3-1.31.4-1.81.51.7-1.5-1.7-1.61.61.92.02.0-1.91.9-2.22.00.1-2.32.02.1-1.9-1.92.2-2.1-2.2-0.2
Short access day 10 total inactive lever presses0.60.61.60.2-0.0-0.50.40.5-0.4-0.6-0.50.60.70.90.9-0.80.8-1.10.9-0.2-1.30.91.1-0.9-0.91.2-1.1-1.20.1
Short access day 1 total infusions0.10.10.6-0.70.7-0.20.10.3-0.0-0.2-0.20.20.20.30.3-0.20.2-0.10.1-0.5-0.10.10.1-0.3-0.40.00.0-0.10.3
Short access day 10 total infusions0.20.30.50.3-0.30.5-0.5-0.50.50.50.5-0.5-0.5-0.6-0.60.5-0.50.6-0.6-0.40.6-0.5-0.60.50.5-0.60.70.60.2
Short access total infusions0.00.00.10.1-0.0-0.0-0.0-0.10.00.10.1-0.1-0.1-0.0-0.00.1-0.10.1-0.1-0.00.1-0.0-0.10.10.0-0.10.30.1-0.1
Short access day 1 locomotion0.70.81.20.1-0.50.9-1.1-0.71.10.80.8-0.8-0.8-1.0-1.00.8-0.91.0-0.9-1.00.9-1.0-0.90.90.9-1.10.91.00.7
Short access day 10 total locomotion0.40.51.2-0.50.40.4-0.9-0.30.80.40.4-0.5-0.5-1.1-1.10.5-0.70.7-0.7-0.40.6-0.8-0.70.81.1-0.90.60.90.3
Short access total locomotion0.80.81.40.3-0.40.9-1.2-0.71.10.80.8-0.8-0.8-1.2-1.20.8-0.91.0-1.0-0.40.9-1.0-1.01.01.2-1.10.91.00.3
One hour access (0.3 mA shock)0.60.71.2-0.70.9-0.91.10.8-0.9-0.8-0.80.70.80.90.9-0.80.8-0.90.90.2-0.90.90.9-0.8-0.70.8-0.9-0.9-0.2
Compulsive drug intake7.67.710.0-2.62.8-2.93.22.8-3.0-2.8-2.82.82.83.23.2-2.72.9-2.82.81.8-2.82.92.8-2.8-2.72.8-2.8-2.8-1.7
One hour access (shock baseline)2.52.93.61.4-1.61.8-1.8-1.71.81.71.7-1.7-1.7-1.9-1.91.7-1.71.7-1.7-1.41.7-1.7-1.71.71.8-1.81.71.71.4
Social response proportion1.01.13.0-1.61.1-1.00.91.2-1.0-1.2-1.21.21.10.90.9-1.11.0-1.00.91.7-0.70.90.8-0.9-0.80.8-0.6-0.7-1.5
Social responses0.10.10.4-0.50.1-0.10.30.3-0.3-0.3-0.30.30.20.10.1-0.20.2-0.30.20.6-0.10.20.1-0.00.00.10.0-0.0-0.3
Social time0.10.11.00.1-0.00.20.3-0.1-0.10.10.2-0.2-0.10.10.10.10.0-0.20.1-0.7-0.0-0.00.00.10.10.1-0.0-0.11.0
Soleus weight1.03.14.72.2-2.01.9-1.8-1.91.71.81.8-1.8-1.8-1.8-1.81.8-1.81.8-1.8-0.71.6-1.7-1.81.71.8-1.61.61.70.8
Bone: stiffness0.00.10.40.20.10.1-0.4-0.20.20.20.1-0.1-0.2-0.2-0.20.2-0.20.3-0.30.60.3-0.3-0.30.00.0-0.30.40.3-0.3
Tibialis anterior weight0.31.01.7-0.71.3-1.31.10.9-1.2-1.0-1.01.00.91.11.1-0.90.9-0.80.91.2-0.70.90.9-1.0-0.90.9-0.9-0.8-1.2
Time to tail flick, vehicle, before self-admin1.81.93.8-1.01.1-1.21.41.3-1.4-1.3-1.31.31.41.41.4-1.41.5-2.01.50.5-1.61.51.5-1.4-1.31.6-1.4-1.6-0.6
Time to tail flick, vehicle, after self-admin0.20.20.50.6-0.70.7-0.5-0.50.50.50.5-0.5-0.4-0.3-0.30.4-0.40.4-0.4-0.70.3-0.4-0.30.30.2-0.30.30.20.6
Time to tail flick, test, before self-admin0.10.10.60.8-0.60.3-0.3-0.30.30.30.3-0.3-0.2-0.4-0.40.2-0.2-0.1-0.1-0.1-0.0-0.1-0.10.40.50.00.20.00.1
Time to tail flick, test, after self-admin0.10.10.20.4-0.30.4-0.0-0.30.00.30.2-0.2-0.3-0.0-0.00.3-0.20.2-0.30.30.3-0.2-0.40.20.1-0.20.40.4-0.3
Delta time to tail flick, vehicle, before/after SA1.61.62.31.4-1.51.3-1.3-1.31.31.31.3-1.3-1.3-1.2-1.21.2-1.31.5-1.3-1.11.2-1.3-1.21.21.1-1.21.21.11.0
Delta time to tail flick, test, before/after SA0.30.31.0-1.00.7-0.40.50.6-0.5-0.5-0.60.60.50.60.6-0.40.4-0.20.30.7-0.20.40.2-0.5-0.60.2-0.4-0.2-0.8
Tibia length0.31.02.41.6-1.31.0-0.8-1.00.61.00.8-0.8-1.0-0.8-0.81.0-1.01.2-1.00.91.1-1.0-1.10.80.8-0.91.11.1-0.8
Ambulatory time before self-admin0.40.41.3-1.11.0-0.80.50.8-0.6-0.7-0.70.70.70.40.4-0.70.5-0.30.50.5-0.50.50.5-0.5-0.50.3-0.6-0.4-0.6
Ambulatory time after self-admin1.31.52.90.6-0.30.9-1.1-1.10.91.11.0-1.0-1.2-1.1-1.11.3-1.41.7-1.50.21.6-1.4-1.61.21.3-1.71.51.7-0.2
Bone: tissue strength0.10.10.70.8-0.50.4-0.2-0.50.20.40.4-0.4-0.4-0.1-0.10.4-0.40.3-0.3-0.20.2-0.2-0.30.30.2-0.20.40.30.2
Total heroin consumption1.61.82.6-0.81.1-1.31.61.2-1.4-1.2-1.21.21.31.51.5-1.31.4-1.61.50.1-1.61.61.5-1.5-1.61.6-1.5-1.6-0.1
Bone: trabecular number0.71.12.60.8-1.01.0-1.2-1.01.21.01.1-1.1-1.0-1.0-1.01.0-0.90.8-1.0-1.60.8-1.0-0.90.80.8-1.01.00.91.6
Bone: trabecular spacing0.00.00.10.00.1-0.10.20.0-0.1-0.0-0.00.00.10.00.0-0.00.00.00.1-0.2-0.10.10.10.00.10.1-0.3-0.20.2
Bone: trabecular thickness1.41.62.51.6-1.31.2-1.4-1.41.21.31.2-1.2-1.4-1.4-1.41.3-1.41.3-1.40.01.2-1.3-1.41.31.3-1.31.31.4-0.1
Bone: trabecular tissue density0.10.10.4-0.30.5-0.40.40.3-0.4-0.3-0.40.40.40.20.2-0.40.3-0.30.30.2-0.40.30.4-0.3-0.20.4-0.6-0.4-0.2
Water consumed over 24 hours0.20.20.5-0.30.5-0.50.70.4-0.5-0.4-0.40.40.40.50.5-0.40.5-0.70.5-0.2-0.50.50.5-0.4-0.40.5-0.5-0.60.2
Number of responses in last shaping day0.20.21.61.3-1.00.2-0.0-0.60.20.40.5-0.4-0.40.00.00.4-0.20.1-0.1-0.70.2-0.1-0.10.20.00.10.3-0.10.5