Hub : Genes

Nek7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Nek7 0.17 0.07 0.0e+00 0.16 0.19 0.18 0.18 2.4e-14 8.3e-18 2.1e-16 1.2e-16
2 LHb gene expression Nek7 0.16 0.1 2.1e-03 0.12 0.09 0.07 0.09 1.0e-03 3.2e-03 9.2e-03 3.3e-03
3 NAcc gene expression Nek7 0.08 0.04 1.7e-16 0.1 0.1 0.1 0.09 6.7e-15 9.2e-15 6.0e-15 3.1e-13
4 Brain isoform ratio NM_001108346.3 0.05 0.03 5.5e-05 0.03 0.04 0.04 0.03 1.2e-03 1.0e-04 1.4e-04 3.6e-04
5 BLA gene expression Nek7 0.23 0.11 2.0e-10 0.11 0.17 0.15 0.14 1.4e-06 2.4e-09 3.6e-08 6.2e-08
6 Brain mRNA stability Nek7 0.04 0.03 4.3e-04 0.04 0.03 0.03 0.02 1.8e-04 1.8e-03 1.7e-03 2.7e-03
7 pVTA gene expression Nek7 0.14 0.06 1.1e-16 0.21 0.22 0.22 0.22 1.0e-16 1.1e-17 1.1e-17 6.7e-18
8 Adipose mRNA stability Nek7 0.2 0.1 4.4e-16 0.1 0.11 0.11 0.11 3.0e-11 3.2e-12 4.6e-12 8.7e-12
9 Liver gene expression Nek7 0.02 0.02 5.5e-03 0.02 0.01 0 0.01 5.8e-03 1.9e-02 7.3e-02 1.5e-02
10 LHb isoform ratio NM_001108346.3 0.19 0.12 8.8e-03 0.07 0.04 0.01 0.06 9.4e-03 4.0e-02 1.8e-01 1.8e-02
11 Brain isoform ratio XM_063272470.1 0.06 0.04 1.1e-05 0.05 0.05 0.05 0.04 2.0e-05 2.5e-05 3.8e-05 4.7e-05
12 Adipose isoform ratio NM_001108346.3 0.05 0.04 9.3e-04 0.02 0.01 0 0.01 9.7e-04 1.6e-02 2.3e-01 8.7e-03
13 Adipose isoform ratio XM_063272470.1 0.17 0.08 0.0e+00 0.12 0.12 0.11 0.12 1.7e-13 1.1e-12 1.3e-12 3.9e-13
14 Adipose gene expression Nek7 0.4 0.13 0.0e+00 0.28 0.34 0.33 0.32 1.6e-31 2.5e-38 4.5e-37 6.1e-37
15 PL gene expression Nek7 0.06 0.04 3.0e-05 0.04 0.04 0.04 0.04 3.6e-05 2.2e-05 3.3e-05 3.9e-05
16 OFC gene expression Nek7 0.31 0.15 6.8e-04 0.04 0.11 0.07 0.12 3.3e-02 1.2e-03 9.7e-03 8.9e-04
17 LHb intron excision ratio chr13_52590842_52603675 0.28 0.15 1.6e-04 0.2 0.17 0.18 0.23 1.4e-05 6.0e-05 4.8e-05 4.3e-06
18 LHb intron excision ratio chr13_52576666_52586730 0.26 0.15 5.2e-04 0.18 0.16 0.16 0.23 3.6e-05 1.7e-04 1.1e-04 3.7e-06
19 Adipose intron excision ratio chr13_52576666_52586730 0.24 0.1 0.0e+00 0.25 0.24 0.25 0.24 3.1e-27 1.4e-26 2.3e-27 5.6e-27
20 Adipose intron excision ratio chr13_52590842_52603675 0.23 0.1 0.0e+00 0.23 0.23 0.23 0.23 1.1e-24 2.3e-25 1.3e-25 1.7e-25

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density2.54.47.1-2.5-2.5-2.6-2.6-2.7-2.4-2.4-2.4-2.3-2.32.4-2.42.4-1.6-2.2-1.3-0.1-0.00.4-0.3
Area under the delay curve0.80.92.41.11.01.30.50.51.01.10.81.10.00.0-0.00.01.1-0.2-0.51.6-1.5-1.31.3
BMI with tail2.38.013.8-3.4-3.6-2.9-3.7-3.6-2.6-2.5-2.6-2.2-3.73.4-3.43.4-1.3-3.5-3.40.3-0.2-0.80.7
BMI without tail2.36.915.0-3.5-3.9-3.5-3.2-3.0-3.2-3.3-3.0-2.7-2.32.3-2.32.3-2.5-2.0-1.1-1.71.71.2-1.2
Body weight3.716.431.0-4.5-4.6-3.8-5.2-5.2-3.4-3.4-3.8-2.9-5.65.2-5.25.2-1.6-5.3-4.61.0-0.9-1.61.6
Weight adjusted by age0.60.92.7-0.5-0.6-0.70.20.2-0.6-0.8-0.2-1.10.9-0.50.5-0.5-1.01.00.8-1.61.61.5-1.5
Bone surface4.58.112.7-3.6-3.3-3.4-3.6-3.6-3.3-3.3-3.4-3.3-3.23.2-3.23.2-2.5-2.8-1.6-0.50.40.5-0.4
Bone volume3.46.19.6-3.1-3.0-3.0-3.1-3.1-2.9-2.9-2.9-2.8-2.72.8-2.82.8-2.0-2.5-1.3-0.50.40.5-0.4
Breakpoint value in progressive ratio session0.20.31.10.71.10.60.50.50.70.60.40.20.4-0.20.2-0.20.50.20.50.4-0.3-0.40.4
Number of licking bursts0.00.10.2-0.10.1-0.2-0.3-0.3-0.4-0.4-0.40.1-0.30.3-0.30.3-0.1-0.3-0.0-0.10.10.00.0
Context. condit. distance diff. score1.51.83.41.40.80.91.71.81.01.11.20.91.8-1.81.8-1.80.41.91.7-0.90.90.8-0.8
Locomotion velocity, session 10.20.30.5-0.6-0.6-0.6-0.6-0.7-0.5-0.4-0.5-0.6-0.60.6-0.60.6-0.3-0.6-0.3-0.30.3-0.20.2
Locomotion distance, session 10.20.20.4-0.6-0.6-0.5-0.5-0.5-0.6-0.5-0.3-0.5-0.50.4-0.40.4-0.3-0.4-0.4-0.20.2-0.10.1
Locomotion velocity, session 20.30.30.8-0.6-0.2-0.6-0.6-0.7-0.9-0.7-0.7-0.6-0.60.6-0.60.6-0.6-0.4-0.30.2-0.20.1-0.1
Locomotion distance, session 20.81.12.8-0.8-0.6-1.1-0.3-0.4-1.5-1.4-1.2-1.40.2-0.20.2-0.2-1.70.61.1-1.21.21.6-1.6
Locomotion velocity, session 30.10.20.8-0.2-0.3-0.30.10.0-0.4-0.3-0.1-0.40.1-0.10.1-0.1-0.40.40.6-0.90.90.5-0.5
Locomotion distance, session 32.12.26.5-1.1-1.6-1.5-0.3-0.3-1.6-1.5-1.0-1.50.6-0.50.5-0.5-1.90.91.5-2.52.62.3-2.3
Stereotopy head waving bouts, day 30.30.40.90.81.00.70.80.70.50.40.50.50.8-0.70.7-0.70.20.70.9-0.20.20.2-0.2
Stereotopy head waving duration, day 30.80.92.51.31.61.51.00.91.21.21.21.10.3-0.30.3-0.31.20.30.10.8-0.8-1.01.0
Locomotion velocity, session 71.31.43.1-1.2-1.0-1.1-0.6-0.7-1.5-1.4-1.2-1.7-0.30.3-0.30.3-1.70.21.2-1.71.81.4-1.5
Locomotion distance, session 70.70.82.5-0.5-0.2-0.50.1-0.0-0.9-0.8-0.5-0.90.5-0.50.5-0.5-1.10.71.4-1.61.61.4-1.4
Stereotopy head waving bouts, day 71.92.24.01.91.92.01.71.71.91.91.91.91.3-1.21.2-1.21.71.00.20.8-0.7-0.70.7
Stereotopy head waving duration, day 71.01.22.11.41.31.41.41.41.41.41.41.31.0-1.01.0-1.01.11.00.50.1-0.0-0.30.3
Locomotion velocity, session 80.50.51.20.60.40.51.00.90.20.40.70.50.9-0.70.7-0.70.01.11.1-1.01.00.6-0.6
Locomotion distance, session 81.82.65.70.90.40.41.71.80.30.40.80.42.3-2.22.2-2.2-0.52.42.3-1.81.81.9-1.9
Degree of sensitization distance0.20.20.70.10.60.4-0.1-0.30.30.30.10.1-0.50.4-0.40.40.4-0.6-0.40.8-0.8-0.80.8
Degree of sensitization stereotypy1.92.14.11.81.61.91.61.62.02.02.02.01.2-1.21.2-1.21.90.9-0.00.7-0.6-0.80.8
Conditioned locomotion1.11.33.0-0.6-0.9-0.4-1.2-1.1-0.2-0.2-0.5-0.0-1.51.4-1.41.40.4-1.7-1.71.3-1.2-1.31.3
Cocaine response after cond. corrected0.10.10.3-0.2-0.0-0.20.00.1-0.4-0.3-0.2-0.20.2-0.50.5-0.5-0.40.50.2-0.10.10.6-0.5
Cocaine response after cond. not corrected0.81.02.7-0.9-0.7-1.0-0.4-0.3-1.2-1.1-1.0-1.20.3-0.50.5-0.5-1.50.60.8-1.21.11.6-1.6
Cocaine response before conditioning1.01.23.1-0.9-0.7-1.1-0.5-0.5-1.0-1.1-1.2-1.50.1-0.00.0-0.0-1.80.41.2-1.61.61.6-1.6
Saline control response0.40.51.5-0.40.2-0.4-0.0-0.1-0.6-0.6-0.7-0.80.4-0.30.3-0.3-1.20.61.1-0.90.91.2-1.2
Bone: connectivity density4.06.310.4-2.9-2.8-3.0-3.2-3.2-2.7-2.8-3.0-2.8-2.82.9-2.92.9-2.0-2.8-1.70.1-0.20.1-0.1
Bone: cortical apparent density0.60.81.91.01.30.71.11.10.50.50.30.51.2-1.11.1-1.1-0.11.41.3-0.10.00.8-0.7
Bone: cortical area2.94.57.4-2.6-2.3-2.3-2.7-2.7-2.3-2.2-2.2-2.3-2.62.5-2.52.5-1.4-2.3-1.90.2-0.3-0.30.3
Bone: cortical porosity3.03.26.3-2.4-2.1-2.3-2.1-2.1-2.5-2.5-2.1-2.2-1.81.6-1.61.6-1.9-1.3-1.1-0.50.50.7-0.7
Bone: cortical porosity2.22.45.1-2.1-1.7-2.0-1.8-1.8-2.3-2.2-1.9-1.8-1.51.3-1.31.3-1.7-1.0-0.8-0.40.40.7-0.7
Bone: cortical thickness1.32.14.0-1.3-0.9-1.1-1.7-1.7-1.4-1.2-1.5-1.1-2.01.9-1.91.9-0.6-1.7-1.61.3-1.3-0.70.8
Bone: cortical thickness1.51.83.4-1.6-1.7-1.8-1.4-1.3-1.9-1.7-1.9-1.8-1.00.9-0.90.9-1.8-0.50.1-0.90.81.1-1.1
Bone: cortical tissue density0.60.81.81.01.20.71.11.10.50.50.30.61.2-1.11.1-1.1-0.11.41.3-0.10.10.8-0.8
Condit. Reinf. active minus inactive responses0.50.51.0-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.9-1.0-0.70.7-0.70.7-0.6-0.7-0.80.2-0.2-0.0-0.0
Condit. Reinf. active-inactive response ratio0.50.52.1-0.0-0.30.1-0.4-0.40.30.20.10.3-0.60.6-0.60.60.7-0.9-1.41.2-1.2-1.11.1
Condit. Reinf. active responses1.11.33.3-1.3-1.3-1.5-0.9-0.9-1.5-1.5-1.5-1.8-0.20.2-0.20.2-1.70.00.4-1.11.11.3-1.3
Condit. Reinf. inactive responses1.82.25.1-1.2-1.0-1.5-0.4-0.4-1.7-1.7-1.5-2.00.3-0.40.4-0.4-2.20.81.6-2.02.02.2-2.2
Incentive salience index mean1.21.53.6-1.6-1.4-1.6-1.3-1.3-1.7-1.7-1.7-1.9-0.80.7-0.70.7-1.6-0.6-0.5-0.30.30.9-0.9
Condit. Reinf. lever presses0.60.92.4-1.1-0.8-1.1-0.6-0.6-1.3-1.3-1.2-1.5-0.1-0.10.1-0.1-1.50.20.2-0.60.61.2-1.3
Condit. Reinf. active minus inactive responses3.24.111.9-1.5-1.8-1.9-0.3-0.3-2.0-2.0-1.3-1.70.7-0.80.8-0.8-2.51.32.4-3.53.43.2-3.2
Condit. Reinf. active-inactive response ratio1.41.65.4-0.3-0.8-0.50.60.5-0.7-0.60.1-0.41.2-1.11.1-1.1-0.91.31.8-2.32.32.0-2.0
Condit. Reinf. active responses3.04.210.5-1.8-2.0-2.1-0.7-0.7-2.2-2.3-1.7-2.10.2-0.30.3-0.3-2.70.92.2-3.23.23.0-3.1
Condit. Reinf. inactive responses1.72.24.5-1.7-1.3-1.8-1.5-1.5-1.9-1.9-2.1-2.0-1.11.1-1.11.1-2.1-0.60.6-1.11.11.3-1.3
Condit. Reinf. lever presses2.73.78.8-1.7-1.5-2.0-0.8-0.8-2.3-2.4-1.9-2.10.2-0.20.2-0.2-2.80.72.0-2.72.73.0-2.9
Condit. Reinf. lever reinforcers received3.85.314.3-1.8-2.1-2.2-0.5-0.5-2.3-2.4-1.7-2.20.7-0.70.7-0.7-3.01.42.8-3.83.83.7-3.7
Conditioned reinforcement - actives1.01.73.7-1.9-1.7-1.8-1.6-1.6-1.9-1.8-1.7-1.6-0.70.6-0.60.6-1.6-1.0-0.7-0.60.60.9-0.9
Conditioned reinforcement - inactives2.33.45.4-2.2-2.2-1.9-2.3-2.3-1.8-1.9-2.3-2.2-2.02.3-2.32.3-1.8-1.9-0.7-0.40.30.4-0.4
Conditioned locomotion0.40.61.7-1.1-1.2-0.9-1.0-0.9-1.0-0.9-0.7-1.3-0.60.4-0.40.4-0.7-0.7-0.7-0.00.00.3-0.3
Patch foraging indifference point 0 sec0.81.64.11.52.01.71.41.31.51.61.41.31.2-1.11.1-1.11.20.90.41.0-1.0-0.60.5
Patch foraging indifference point AUC0.10.21.20.60.50.50.40.40.50.60.61.10.20.1-0.10.10.7-0.00.0-0.10.1-0.30.3
Delay disc. indifference point, 0s delay1.51.64.31.30.71.40.70.81.81.81.62.1-0.0-0.20.2-0.22.1-0.4-0.91.1-1.0-1.81.8
Delay disc. indifference point, 16s delay0.70.71.51.00.91.20.60.61.01.21.01.00.3-0.20.2-0.21.20.0-0.41.0-1.0-1.11.1
Delay disc. indifference point, 2s delay1.21.33.40.70.80.9-0.1-0.20.90.90.41.0-1.00.9-0.90.91.3-1.1-1.51.8-1.7-1.81.8
Delay disc. indifference point, 24s delay0.40.41.10.90.91.00.70.70.50.70.50.60.4-0.50.5-0.50.50.50.21.0-1.1-0.40.4
Delay disc. indifference point, 4s delay1.21.22.71.41.51.51.01.01.31.41.11.10.6-0.60.6-0.61.20.4-0.21.6-1.6-0.90.9
Delay disc. indifference point, 8s delay0.00.00.20.0-0.1-0.0-0.10.0-0.1-0.1-0.10.1-0.00.1-0.10.1-0.1-0.10.40.2-0.1-0.00.1
Indifference point function ln k0.61.02.90.10.50.5-0.5-0.50.50.50.1-0.0-1.11.0-1.01.00.8-1.1-1.41.7-1.7-1.61.6
Indifference point function log k0.61.02.90.10.50.5-0.5-0.50.50.50.1-0.0-1.11.0-1.01.00.8-1.1-1.41.7-1.7-1.61.6
Patch foraging total patch changes 0 sec0.61.12.91.31.71.41.31.21.11.21.11.01.2-1.11.1-1.10.91.00.70.6-0.6-0.20.2
Patch foraging total patch changes 12 sec0.70.91.51.21.10.91.21.21.00.91.01.11.2-1.01.0-1.00.61.10.9-0.10.10.3-0.3
Patch foraging total patch changes 18 sec1.11.73.11.61.61.31.71.71.11.21.21.31.8-1.51.5-1.50.71.61.2-0.10.10.5-0.5
Patch foraging total patch changes 24 sec0.30.51.10.40.00.40.80.80.60.60.90.90.9-0.80.8-0.80.40.80.9-1.01.00.4-0.4
Patch foraging total patch changes 6 sec1.11.73.11.51.81.71.51.41.51.71.71.71.3-1.11.1-1.11.60.90.20.6-0.6-0.70.7
Patch foraging time to switch 0 sec0.40.92.70.70.40.51.01.20.60.50.70.41.4-1.71.7-1.70.11.30.8-0.30.30.6-0.6
Patch foraging water rate 0 sec0.10.10.30.20.40.40.1-0.00.20.40.30.4-0.30.5-0.50.50.4-0.20.1-0.00.1-0.50.5
Patch foraging water rate 12 sec0.20.41.0-1.0-0.9-0.9-0.7-0.7-0.9-0.9-0.6-0.6-0.40.1-0.10.1-0.6-0.3-0.3-0.60.60.5-0.5
Patch foraging water rate 18 sec0.40.71.50.80.71.10.90.90.91.11.21.10.6-0.90.9-0.91.00.50.20.0-0.0-0.40.5
Patch foraging water rate 24 sec0.10.20.4-0.7-0.6-0.3-0.5-0.5-0.4-0.3-0.2-0.4-0.70.5-0.50.5-0.2-0.3-0.2-0.30.3-0.10.1
Patch foraging water rate 6 sec0.40.51.0-0.9-0.9-0.8-0.9-1.0-0.8-0.8-0.7-0.4-1.00.9-0.90.9-0.3-0.9-0.6-0.10.1-0.10.1
Seeking ratio, delayed vs. immediate footshock2.12.65.91.81.21.42.02.01.41.31.81.82.2-2.42.4-2.41.21.70.9-0.00.20.1-0.1
Distance traveled before self-admin0.81.12.81.31.01.50.80.81.51.71.21.10.4-0.30.4-0.41.30.1-0.71.2-1.1-1.21.2
Distance traveled after self-admin0.91.14.0-1.2-0.9-0.7-1.3-1.3-1.1-0.8-1.2-1.3-1.01.0-1.01.0-0.8-1.1-2.00.7-0.6-0.20.2
Extensor digitorum longus weight0.93.66.4-2.5-2.5-2.4-2.4-2.5-2.2-2.3-2.0-1.9-2.02.0-2.02.0-1.3-2.0-1.4-0.70.60.2-0.2
Bone: elastic displacement0.50.61.50.91.10.71.01.00.60.50.40.60.9-1.01.0-1.00.01.01.2-0.30.30.4-0.4
Bone: elastic work0.50.61.30.80.80.71.01.10.60.60.70.60.9-1.01.0-1.00.21.11.1-0.50.50.5-0.4
Bone: endosteal estimation0.20.51.5-1.2-1.2-0.8-0.8-0.9-0.6-0.6-0.1-0.9-0.80.6-0.60.6-0.2-0.7-0.7-0.80.9-0.10.0
Bone: endosteal perimeter1.53.36.9-2.2-2.2-1.5-2.3-2.4-1.2-1.2-1.0-1.6-2.42.2-2.22.2-0.2-2.6-2.30.00.0-1.21.2
Epididymis fat weight1.24.28.4-2.0-2.3-1.4-2.6-2.4-1.3-1.1-1.6-1.5-2.82.8-2.72.7-0.5-2.8-2.91.1-1.0-1.41.3
Delta time in closed arm before/after self-admin0.90.92.10.60.70.6-0.1-0.10.90.80.31.1-0.70.9-0.90.91.1-0.9-0.91.3-1.3-1.41.4
Delta time in open arm before/after self-admin0.60.62.01.0-0.10.50.91.11.00.70.80.51.4-0.90.9-0.90.40.80.8-0.60.60.3-0.3
Diff in mean of infusions in LGA sessions0.10.10.7-0.3-0.1-0.3-0.4-0.5-0.0-0.3-0.5-0.8-0.30.5-0.60.6-0.3-0.4-0.2-0.20.10.1-0.0
Delay discount exponential model param0.91.02.8-1.2-1.3-1.4-0.7-0.7-1.1-1.2-0.9-1.1-0.20.2-0.20.2-1.1-0.00.3-1.71.61.2-1.2
Extinction: sum of active levers before priming0.60.71.40.90.60.71.01.01.21.01.21.01.1-1.00.8-0.80.80.70.3-0.30.3-0.10.1
Active lever presses in extinction session 60.30.31.30.2-0.3-0.20.40.40.6-0.00.4-0.40.6-0.50.5-0.50.10.51.1-1.11.10.5-0.5
Bone: final force0.60.92.8-1.5-1.7-1.3-1.0-1.0-1.2-1.2-0.8-1.1-0.70.6-0.60.6-0.9-0.4-0.4-1.01.00.8-0.7
Bone: final moment0.50.92.5-1.4-1.6-1.2-0.9-0.9-1.1-1.1-0.7-1.1-0.60.6-0.60.6-0.8-0.4-0.3-1.01.00.7-0.7
Food consumed during 24 hour testing period0.60.91.8-1.0-0.5-0.9-1.1-1.3-0.9-0.9-0.9-0.9-1.31.3-1.31.3-0.4-1.2-0.6-0.10.1-0.40.5
Glucose1.72.76.8-1.1-1.4-1.6-0.3-0.2-1.5-1.6-1.4-1.50.5-0.60.6-0.6-2.31.12.0-2.62.52.6-2.6
Heart weight0.81.22.61.30.81.31.21.11.61.61.61.40.7-0.70.7-0.71.50.60.00.7-0.6-1.01.0
Delay discount hyperbolic model param0.91.03.3-1.1-1.2-1.3-0.6-0.6-1.0-1.1-0.8-1.1-0.0-0.00.0-0.0-1.10.20.5-1.81.81.3-1.2
Intermittent access intake day 1-15 change0.10.20.50.20.50.40.0-0.10.40.50.4-0.1-0.20.1-0.10.10.6-0.5-0.70.7-0.7-0.60.6
Intermittent access intake escalation0.10.10.5-0.30.0-0.0-0.3-0.4-0.1-0.0-0.1-0.5-0.50.4-0.40.40.2-0.6-0.70.5-0.4-0.30.3
Intermittent access intake escalation 21.01.12.01.31.31.41.21.01.11.31.40.81.2-1.21.2-1.21.20.40.20.5-0.5-0.40.3
Intermitt. access day 1 inactive lever presses1.55.710.6-3.1-3.3-3.0-2.8-2.8-2.6-2.8-2.8-2.7-2.22.3-2.32.3-2.6-1.8-0.6-1.71.61.4-1.4
Intermitt. access day 15 inactive lever presses1.02.03.9-1.7-2.0-1.7-1.6-1.6-1.4-1.4-1.7-2.0-1.51.3-1.41.4-1.5-1.2-0.1-1.01.00.7-0.7
Intermitt. access escalation Index1.42.04.3-1.4-1.4-1.8-0.8-0.9-1.5-1.8-1.6-1.80.1-0.30.2-0.2-2.10.21.3-1.91.91.9-1.9
Intermittent access day 1 total infusions1.01.63.6-1.7-1.9-1.7-1.5-1.4-1.7-1.6-1.6-1.4-0.60.5-0.50.5-1.6-1.0-0.0-0.90.90.9-0.9
Intermittent access day 15 total infusions0.91.32.5-1.6-1.5-1.4-1.5-1.5-1.5-1.4-1.4-1.0-1.00.9-1.01.0-1.1-1.2-0.8-0.10.10.3-0.3
Intermittent access terminal intake (last 3 days)0.30.41.4-0.8-0.7-0.6-0.9-1.0-0.6-0.4-0.7-0.3-0.50.4-0.40.4-0.3-1.2-0.90.5-0.5-0.30.3
Intermittent access total infusions1.41.73.3-1.8-1.7-1.7-1.8-1.7-1.7-1.6-1.7-1.2-1.00.9-0.90.9-1.4-1.3-0.7-0.40.40.5-0.5
Intermittent access day 1 locomotion2.73.48.7-2.5-2.9-2.5-2.3-2.2-2.3-2.3-2.2-1.7-1.31.3-1.41.4-1.9-1.6-0.6-1.31.21.0-1.0
Intermittent access day 15 total locomotion0.20.31.1-0.7-1.0-0.7-0.8-0.8-0.2-0.4-0.4-0.5-0.50.7-0.70.7-0.1-0.9-0.5-0.10.1-0.20.2
Intermittent access total locomotion1.31.63.7-1.8-1.9-1.6-1.7-1.7-1.4-1.4-1.4-1.4-1.01.1-1.11.1-1.1-1.4-1.0-0.30.30.4-0.4
Intermittent access standard deviation0.61.22.8-1.5-1.2-1.1-1.5-1.7-1.3-1.1-1.2-1.1-1.31.1-1.01.0-0.8-1.6-1.20.4-0.40.0-0.1
Left kidney weight0.42.14.1-1.4-1.5-1.3-1.9-1.8-1.0-1.0-1.4-0.8-2.01.9-1.91.9-0.5-2.0-1.50.7-0.9-0.90.9
Right kidney weight1.04.47.4-2.5-2.3-2.5-2.7-2.7-2.4-2.4-2.6-2.2-2.52.3-2.32.3-1.8-2.3-1.4-0.0-0.10.2-0.2
Cocaine induced anxiety0.30.41.0-0.5-0.8-0.6-0.2-0.1-0.5-0.5-0.4-1.00.10.2-0.30.3-0.90.20.5-1.00.90.9-0.9
Post-drug Anxiety0.40.41.3-0.3-0.5-0.30.10.1-0.4-0.4-0.3-0.90.5-0.30.2-0.2-0.90.70.7-1.11.11.1-1.1
Baseline Anxiety0.30.41.20.70.60.90.70.50.80.90.81.10.3-0.50.5-0.51.00.2-0.00.2-0.1-0.60.6
Tail length1.35.29.6-2.8-3.0-3.1-2.3-2.3-3.0-3.1-2.8-2.6-1.41.6-1.61.6-2.8-1.10.6-2.12.01.8-1.8
Length with tail0.93.97.4-2.1-1.9-1.8-2.5-2.6-1.6-1.7-1.9-1.4-2.72.7-2.72.7-0.8-2.7-1.90.8-0.8-0.90.9
Length without tail2.27.118.0-0.60.00.3-2.0-2.10.10.3-0.40.2-3.53.2-3.23.21.6-3.6-4.23.9-3.9-3.63.6
Times rat made contact with spout0.60.72.51.11.60.91.11.00.50.40.40.50.9-0.90.9-0.90.01.11.30.2-0.30.4-0.4
Lifetime Intake1.41.73.3-1.8-1.6-1.6-1.8-1.8-1.7-1.5-1.7-1.2-1.11.1-1.11.1-1.3-1.4-1.10.1-0.10.3-0.3
Liver weight, left4.67.512.6-3.4-3.6-3.2-3.5-3.4-3.1-2.9-3.1-3.1-3.03.0-3.03.0-2.3-2.8-1.8-0.91.00.2-0.2
Liver weight, right4.17.111.7-3.2-3.3-3.0-3.4-3.4-2.8-2.8-3.0-2.8-3.13.1-3.13.1-2.0-3.0-1.9-0.40.3-0.00.0
Locomotor activity0.10.20.6-0.40.1-0.5-0.4-0.4-0.7-0.7-0.7-0.70.10.3-0.30.3-0.8-0.10.1-0.00.00.6-0.6
Locomotor testing distance0.30.62.2-0.00.60.1-0.5-0.60.00.1-0.4-0.0-0.51.0-1.01.00.2-1.0-1.21.5-1.5-0.80.8
Locomotor testing rearing0.20.51.4-0.4-0.3-0.7-0.2-0.1-0.5-0.6-0.8-0.90.5-0.10.1-0.1-1.20.40.8-0.90.91.2-1.2
Locomotion in novel chamber0.40.51.90.11.10.3-0.3-0.4-0.1-0.0-0.3-0.6-0.30.6-0.60.60.1-0.6-1.31.4-1.3-0.50.5
Locomotion in novel chamber post-restriction0.61.01.91.21.11.11.21.41.01.01.20.61.4-1.31.3-1.30.81.20.10.6-0.70.1-0.0
Fecal boli incidents, locomotor time 10.40.53.1-0.3-0.5-0.6-0.00.0-0.3-0.4-0.3-0.40.2-0.20.2-0.2-0.60.41.5-1.71.80.6-0.6
Change in fecal boli incidents, locomotor task1.51.52.61.61.61.41.51.60.91.01.21.01.4-1.61.6-1.60.91.40.20.9-0.90.1-0.1
Time >=10cm from walls, locomotor time 13.63.86.72.31.92.02.42.52.01.92.22.12.3-2.62.6-2.61.62.11.10.00.0-0.00.0
Bouts of movement, locomotor time 11.31.42.8-1.4-1.6-1.1-1.5-1.5-0.9-0.8-0.9-0.6-1.61.7-1.71.7-0.5-1.5-0.6-0.91.0-0.40.4
Total resting periods, locomotor time 10.40.51.0-0.9-1.0-0.6-0.8-0.8-0.5-0.4-0.4-0.2-0.80.9-0.90.9-0.2-0.8-0.3-0.70.8-0.30.2
Rest time, locomotor task time 10.30.41.50.2-0.50.20.40.50.80.50.80.60.6-0.40.4-0.40.60.30.7-1.01.2-0.20.2
Distance moved, locomotor task time 10.20.20.7-0.10.5-0.10.10.1-0.6-0.5-0.6-0.60.2-0.40.4-0.4-0.90.60.10.2-0.40.8-0.8
Vertical activity count, locomotor time 10.20.51.3-0.7-0.3-0.7-0.8-0.8-1.0-0.9-1.1-0.8-0.80.7-0.70.7-1.1-0.4-0.30.4-0.50.5-0.5
Time >=10cm from walls, locomotor time 21.21.84.31.72.11.81.51.51.41.61.42.11.0-1.31.3-1.31.21.10.30.9-1.0-0.50.5
Bouts of movement, locomotor time 22.03.27.0-1.8-1.5-1.4-2.2-2.3-1.2-1.2-1.6-1.0-2.42.6-2.62.6-0.6-2.3-2.00.9-0.9-1.00.9
Total resting periods, locomotor time 21.52.66.1-1.6-1.4-1.2-2.0-2.0-0.9-1.0-1.3-0.7-2.12.5-2.52.5-0.4-2.2-1.80.9-0.9-1.01.0
Rest time, locomotor task time 20.30.30.90.60.60.70.60.60.90.80.80.70.9-0.40.4-0.40.70.30.00.3-0.3-0.40.4
Distance moved, locomotor task time 20.20.31.0-0.5-0.5-0.5-0.5-0.5-0.7-0.8-0.8-0.3-1.00.5-0.50.5-0.8-0.30.1-0.20.10.2-0.2
Vertical activity count, locomotor time 21.31.85.8-1.1-0.8-0.8-1.6-1.6-1.1-1.0-1.4-0.9-2.41.9-1.91.9-0.6-1.7-1.10.6-0.7-0.60.7
Light reinforcement 11.94.69.02.11.81.42.62.61.61.51.71.93.0-2.82.8-2.80.62.83.0-1.51.61.3-1.3
Light reinforcement 21.42.24.41.61.51.11.81.91.21.21.31.42.1-1.91.9-1.90.62.01.8-0.60.60.6-0.6
Bone: marrow area0.20.51.3-1.1-1.1-0.7-0.7-0.8-0.6-0.6-0.1-0.8-0.70.6-0.60.6-0.1-0.7-0.7-0.80.8-0.10.1
Bone: maximum diameter2.34.38.5-2.3-2.1-1.7-2.6-2.7-1.5-1.4-1.5-1.6-2.82.7-2.72.7-0.3-2.9-2.80.7-0.7-1.51.4
Bone: maximum force1.83.27.0-2.5-2.6-2.4-1.9-1.9-2.3-2.3-1.8-2.3-1.41.3-1.31.3-1.9-0.9-0.5-1.41.41.3-1.3
Bone: maximum moment1.62.96.1-2.4-2.5-2.3-1.7-1.7-2.2-2.2-1.7-2.2-1.21.2-1.21.2-1.8-0.7-0.4-1.51.41.3-1.2
Mean time between licks in bursts0.20.51.9-0.9-1.4-1.1-0.7-0.7-0.6-0.7-0.7-0.5-0.30.3-0.30.3-0.7-0.30.1-1.01.00.5-0.6
Mean num. licks in bursts0.30.51.00.70.70.60.90.90.60.50.50.10.9-0.90.9-0.9-0.11.01.0-0.20.10.5-0.5
Cd content in liver3.13.58.91.81.92.11.00.92.22.32.12.7-0.20.0-0.00.03.0-0.7-1.42.2-2.1-2.72.7
Co content in liver3.33.88.32.32.12.61.91.82.82.92.82.61.1-1.01.0-1.02.90.5-0.31.2-1.1-1.91.8
Cu content in liver1.72.14.01.71.71.91.31.31.81.81.71.80.7-0.90.9-0.92.00.3-0.41.4-1.4-1.61.6
Fe content in liver0.20.30.70.10.10.10.40.5-0.2-0.20.0-0.10.7-0.80.8-0.8-0.40.80.8-0.50.50.8-0.8
K content in liver1.01.03.3-0.00.30.3-0.5-0.50.20.3-0.00.1-1.10.9-0.90.90.6-1.1-1.61.8-1.8-1.51.4
Mg content in liver0.60.71.5-0.4-0.2-0.0-0.7-0.8-0.10.0-0.3-0.1-1.01.0-1.01.00.2-1.1-1.21.1-1.1-1.11.1
Mn content in liver0.20.20.70.30.50.50.00.00.10.40.20.4-0.30.2-0.20.20.4-0.3-0.60.8-0.8-0.60.6
Na content in liver0.00.00.1-0.2-0.10.1-0.00.1-0.1-0.00.1-0.20.1-0.00.0-0.0-0.10.2-0.10.0-0.00.1-0.1
Rb content in liver1.31.53.6-0.5-0.5-0.3-1.1-1.2-0.1-0.1-0.3-0.2-1.61.7-1.71.70.7-1.9-1.81.2-1.3-1.61.6
Se content in liver0.70.82.40.10.30.5-0.3-0.40.30.40.40.5-0.90.6-0.60.61.1-1.1-1.61.5-1.5-1.41.4
Sr content in liver3.63.15.82.12.32.31.51.42.42.42.02.20.7-0.70.7-0.72.30.2-0.51.9-1.9-2.12.1
Zn content in liver2.83.18.51.11.41.60.10.01.51.61.11.4-0.90.8-0.80.82.2-1.3-2.22.9-2.9-2.92.8
Bone: minimum diameter0.71.22.6-1.6-1.3-1.2-1.4-1.4-1.2-1.1-0.8-1.4-1.31.2-1.21.2-0.4-1.2-1.4-0.00.0-0.30.3
Time in familiar zone, hab. session 10.20.20.80.50.50.40.20.10.40.40.30.9-0.20.4-0.40.40.6-0.2-0.30.4-0.4-0.60.6
Time in novel zone, hab. session 10.30.30.9-0.1-0.4-0.10.30.30.0-0.10.1-0.40.7-0.70.7-0.7-0.30.70.6-0.90.90.8-0.8
Total zone transitions, hab. session 10.30.41.2-0.5-0.9-0.7-0.2-0.2-0.8-0.7-0.3-0.50.2-0.20.2-0.2-0.60.20.4-1.11.10.9-0.9
Total locomotion distance, hab. session 10.30.40.8-0.6-0.8-0.8-0.4-0.3-0.9-0.8-0.6-0.7-0.00.1-0.10.1-0.80.00.3-0.80.90.8-0.7
Locomotion velocity, hab. session 10.50.71.6-0.9-1.0-1.1-0.6-0.5-1.3-1.1-0.9-1.2-0.10.0-0.00.0-1.20.00.4-1.11.11.1-1.1
Time in familiar zone, hab. session 20.30.31.3-0.8-1.1-0.9-0.6-0.5-0.6-0.7-0.7-0.5-0.20.2-0.20.2-0.7-0.0-0.1-0.60.60.6-0.6
Time in novel zone, hab. session 20.70.72.00.80.91.00.40.21.11.01.00.9-0.20.2-0.20.21.4-0.6-0.60.8-0.8-1.41.4
Total zone transitions, hab. session 21.41.74.60.0-0.1-0.50.70.7-0.7-0.8-0.4-0.61.3-1.41.4-1.4-1.41.62.0-1.81.82.1-2.1
Total locomotion distance, hab. session 21.11.43.9-0.5-0.6-0.90.20.2-1.0-1.1-0.8-1.00.9-1.01.0-1.0-1.61.21.5-1.81.72.0-2.0
Locomotion velocity, hab. session 21.31.84.8-0.7-0.9-1.2-0.00.1-1.3-1.3-0.9-1.20.8-0.90.9-0.9-1.81.11.6-2.02.02.2-2.2
Novel to familiar place preference ratio1.92.14.11.30.91.01.71.81.21.01.41.02.0-2.02.0-2.00.51.81.6-1.31.30.8-0.8
Novelty place preference1.81.93.81.20.91.01.71.71.21.01.41.01.9-1.91.9-1.90.51.71.5-1.21.30.8-0.8
Time in novel zone, NPP test1.81.93.51.31.01.11.71.71.41.21.51.11.9-1.91.9-1.90.71.61.3-1.11.10.5-0.5
Total zone transitions, NPP test0.91.33.5-0.2-0.4-0.60.40.4-0.8-0.8-0.3-0.71.1-1.11.1-1.1-1.11.11.7-1.81.81.9-1.9
Total locomotion distance, NPP test1.21.74.6-0.5-0.6-1.00.10.2-1.2-1.2-0.8-1.21.0-1.01.0-1.0-1.61.11.7-1.91.92.1-2.1
Locomotion velocity, NPP test1.31.95.2-0.5-0.5-1.00.20.3-1.2-1.2-0.8-1.21.1-1.11.1-1.1-1.71.31.9-1.91.92.3-2.3
Intraocular pressure0.10.10.3-0.5-0.5-0.4-0.4-0.4-0.2-0.2-0.3-0.4-0.20.1-0.10.1-0.3-0.2-0.4-0.20.10.2-0.2
Delta distance traveled before/after self-admin2.93.18.2-2.3-1.5-2.2-1.7-1.7-2.9-2.7-2.3-2.6-0.80.8-0.80.8-2.5-0.3-0.2-1.00.91.7-1.8
Delta ambulatory time before/after self-admin2.22.76.6-2.2-1.5-2.1-1.8-1.8-2.6-2.4-2.2-2.4-1.11.1-1.11.1-2.1-0.7-0.7-0.60.61.2-1.3
Parametrial fat weight4.310.120.0-2.9-2.6-2.3-3.9-3.8-2.0-2.1-2.7-1.7-4.44.5-4.54.5-0.7-4.2-4.22.1-2.0-2.12.1
Pavlov. Cond. lever latency0.40.61.70.40.30.6-0.1-0.20.60.70.40.6-0.70.9-0.90.91.0-0.9-0.70.7-0.7-1.31.3
Pavlov. Cond. magazine entry latency0.10.10.4-0.00.10.00.00.1-0.1-0.00.0-0.00.1-0.30.3-0.30.10.1-0.50.6-0.6-0.0-0.0
Pavlov. Cond. change in total contacts0.20.30.7-0.3-0.4-0.40.00.1-0.5-0.5-0.2-0.40.4-0.70.7-0.7-0.60.50.3-0.50.50.8-0.8
Pavlov. Cond. index score0.40.61.6-0.2-0.2-0.50.20.3-0.5-0.5-0.3-0.40.8-1.01.0-1.0-0.81.00.7-0.60.61.2-1.3
Pavlov. Cond. latency score0.40.51.4-0.2-0.2-0.40.20.3-0.4-0.5-0.3-0.40.8-1.01.0-1.0-0.80.90.6-0.60.61.1-1.2
Pavlov. Cond. lever contacts0.40.51.20.0-0.0-0.20.40.5-0.2-0.3-0.1-0.20.9-1.11.1-1.1-0.61.10.7-0.50.51.1-1.1
Pavlov. Cond. magazine entry number0.20.30.80.40.20.50.10.00.60.60.50.7-0.30.5-0.50.50.8-0.5-0.30.2-0.2-0.90.9
Pavlov. Cond. intertrial magazine entries0.40.51.2-0.8-0.8-0.8-0.6-0.7-0.8-0.9-0.8-0.9-0.60.6-0.60.6-0.9-0.30.3-1.01.10.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.50.61.7-0.3-0.3-0.50.20.3-0.5-0.6-0.4-0.50.8-1.01.0-1.0-0.91.00.6-0.60.61.2-1.3
Pavlov. Cond. response bias0.30.40.9-0.6-0.3-0.7-0.2-0.2-0.8-0.8-0.6-0.90.2-0.40.4-0.4-0.90.40.2-0.30.30.9-1.0
Pavlov. Cond. lever latency1.92.56.61.01.21.50.20.21.51.61.21.4-0.70.7-0.70.72.1-0.9-2.22.6-2.5-2.62.5
Pavlov. Cond. magazine entry latency0.81.02.6-0.5-0.6-0.9-0.00.0-0.9-1.0-0.8-0.80.5-0.50.5-0.5-1.30.81.3-1.61.51.6-1.6
Pavlov. Cond. change in total contacts1.22.05.7-0.5-0.7-1.00.10.2-1.1-1.2-0.8-0.90.8-0.90.9-0.9-1.71.12.2-2.42.42.3-2.2
Pavlov. Cond. index score1.62.25.7-0.9-1.1-1.4-0.2-0.2-1.4-1.6-1.2-1.30.6-0.60.6-0.6-2.00.91.9-2.42.32.4-2.4
Pavlov. Cond. latency score1.82.36.0-1.0-1.1-1.5-0.3-0.2-1.5-1.7-1.3-1.50.5-0.50.5-0.5-2.20.91.9-2.32.32.4-2.4
Pavlov. Cond. lever contacts2.43.38.7-1.0-1.3-1.7-0.2-0.1-1.7-1.8-1.4-1.60.9-0.80.8-0.8-2.41.22.5-2.82.83.0-2.9
Pavlov. Cond. magazine entry number1.31.64.40.60.81.1-0.1-0.21.01.10.80.8-0.80.8-0.80.81.5-1.1-1.72.1-2.0-2.12.0
Pavlov. Cond. intertrial magazine entries0.40.61.40.80.71.00.70.71.11.21.11.00.6-0.60.6-0.61.10.2-0.00.4-0.3-0.60.6
Pavlov. Cond. lever-magazine prob. diff.1.41.84.9-0.7-0.9-1.2-0.1-0.0-1.2-1.3-1.0-1.10.7-0.70.7-0.7-1.70.91.8-2.22.22.2-2.2
Pavlov. Cond. response bias1.72.36.4-0.5-0.7-1.10.20.3-1.1-1.2-0.8-1.01.1-1.11.1-1.1-1.81.32.3-2.52.42.5-2.5
Time in closed arm before self-admin0.71.02.31.20.41.01.21.30.91.01.50.80.9-1.31.3-1.31.10.90.7-0.20.2-0.30.3
Time in closed arm after self-admin1.21.33.41.51.21.30.90.81.61.41.41.70.0-0.10.0-0.01.8-0.2-0.10.9-0.8-1.61.6
Time in open arm before self-admin2.73.05.3-2.3-1.3-2.0-2.1-2.2-2.1-2.1-2.3-2.2-2.11.7-1.71.7-1.8-1.4-1.0-0.1-0.00.7-0.7
Time in open arm after self-admin1.11.22.7-1.1-1.7-1.5-0.7-0.5-1.0-1.4-1.2-1.40.4-0.20.2-0.2-1.50.20.5-1.41.31.6-1.6
Bone: periosteal estimation1.43.05.4-2.3-2.1-1.8-2.2-2.2-1.7-1.6-1.4-1.9-2.22.0-2.02.0-0.8-2.0-1.9-0.10.2-0.50.4
Bone: periosteal perimeter1.93.25.8-2.3-2.2-1.7-2.3-2.4-1.4-1.4-1.3-1.7-2.42.2-2.22.2-0.5-2.4-2.10.1-0.1-0.90.9
Bone: post-yield work0.71.02.0-1.4-1.4-1.2-1.2-1.2-1.0-1.1-0.8-1.3-1.21.2-1.21.2-0.7-0.9-0.9-0.40.40.1-0.1
Progressive ratio test 1 active lever presses4.65.710.5-3.2-2.7-3.0-3.0-3.0-3.1-3.0-3.2-2.6-2.02.0-2.02.0-2.8-2.1-1.0-0.70.71.1-1.1
Progressive ratio test 1 breakpoint4.75.710.5-3.2-2.7-3.0-3.0-3.1-3.0-2.9-3.2-2.6-2.02.1-2.12.1-2.8-2.1-1.1-0.70.61.0-1.1
Progressive ratio test 1 inactive lever presses1.82.64.8-2.1-1.9-1.9-2.2-2.1-1.6-1.7-2.1-1.8-1.71.6-1.61.6-1.5-1.8-1.3-0.00.00.3-0.3
Progressive ratio test 2 active lever presses1.92.34.2-2.0-1.9-1.9-2.0-1.9-2.0-1.9-1.8-1.2-1.21.4-1.41.4-1.4-1.5-1.2-0.30.30.5-0.5
Progressive ratio test 2 breakpoint2.12.44.4-2.1-2.0-2.0-2.0-2.0-2.1-2.0-1.9-1.3-1.21.4-1.41.4-1.5-1.4-1.2-0.40.30.6-0.6
Progressive ratio test 2 inactive lever presses1.62.54.8-2.1-2.2-2.0-2.0-1.9-1.8-1.9-1.8-1.7-1.31.6-1.71.7-1.4-1.5-1.0-0.70.60.6-0.6
Incentive Sensitization - Responses0.10.20.6-0.5-0.7-0.6-0.4-0.3-0.6-0.7-0.3-0.40.20.1-0.10.1-0.3-0.1-0.3-0.40.50.5-0.4
Incentive Sensitization - Breakpoint0.20.20.7-0.5-0.8-0.7-0.4-0.3-0.7-0.9-0.4-0.50.20.1-0.10.1-0.4-0.1-0.2-0.60.60.6-0.6
Sum of active levers in priming session hrs 5-60.60.62.50.2-0.1-0.10.50.50.1-0.1-0.0-0.21.1-0.80.6-0.6-0.60.81.6-1.11.10.9-0.9
Progressive ratio0.20.20.8-0.40.4-0.1-0.4-0.5-0.4-0.3-0.3-0.6-0.40.5-0.50.5-0.1-0.4-0.60.9-0.8-0.40.3
Food seeking constrained by brief footshock1.82.26.50.90.91.20.0-0.21.51.21.01.9-1.21.0-1.01.02.2-1.4-1.71.6-1.7-2.52.6
Seeking ratio, punishment vs. effort0.10.21.00.3-0.40.0-0.1-0.00.30.20.11.0-0.60.3-0.30.30.4-0.4-0.3-0.20.2-0.40.5
Retroperitoneal fat weight3.213.927.1-4.6-5.2-3.9-4.9-4.7-3.5-3.3-3.6-3.4-4.64.5-4.44.4-2.1-4.4-3.80.0-0.0-0.70.7
Reaction time number correct0.91.85.6-1.3-1.6-1.5-0.4-0.4-1.6-1.5-0.9-1.00.2-0.40.4-0.4-1.50.61.3-2.32.41.9-1.9
Reaction time mean minus median0.51.33.7-1.5-1.2-1.6-1.0-0.9-1.5-1.6-1.4-1.9-0.40.3-0.30.3-1.70.00.2-0.80.81.2-1.2
Reaction time mean minus median AUC0.61.64.1-1.8-1.7-1.8-1.2-1.2-1.5-1.7-1.4-2.0-0.50.5-0.50.5-1.7-0.2-0.0-1.21.21.1-1.1
Reaction time num false alarms0.60.82.3-1.0-1.0-1.1-0.8-0.7-1.1-1.2-1.3-1.1-0.10.3-0.30.3-1.5-0.00.4-0.60.61.2-1.1
Reaction time num false alarms AUC0.91.43.9-1.2-1.1-1.5-0.9-0.8-1.4-1.6-1.7-1.5-0.10.4-0.40.4-2.00.10.9-1.11.11.6-1.6
Reaction time trials correct on left0.91.85.6-1.3-1.6-1.5-0.4-0.4-1.6-1.5-0.9-1.00.2-0.40.4-0.4-1.50.61.3-2.32.41.9-1.9
Reaction time trials on left1.01.95.7-1.3-1.7-1.6-0.5-0.5-1.7-1.6-1.0-1.10.1-0.30.3-0.3-1.60.61.3-2.42.41.9-1.9
Reaction time mean0.71.14.2-0.00.40.2-0.7-0.70.10.2-0.3-0.3-1.01.1-1.11.10.4-1.1-1.82.0-2.1-1.41.4
Reaction time mean AUC0.61.03.6-0.10.20.2-0.7-0.60.20.2-0.3-0.3-1.01.0-1.01.00.4-1.1-1.71.9-1.9-1.41.3
Median of all reaction times1.31.96.80.40.80.7-0.5-0.50.60.80.10.3-1.11.2-1.21.21.0-1.3-2.12.6-2.6-2.02.0
Reaction time omissions2.02.96.1-2.1-2.0-2.4-1.8-1.7-2.3-2.4-2.4-2.4-0.80.9-0.90.9-2.5-0.6-0.1-0.80.81.5-1.5
Reaction time false alarm rate0.20.20.9-0.4-0.2-0.5-0.5-0.4-0.4-0.6-0.9-0.7-0.00.4-0.40.4-0.9-0.10.2-0.0-0.00.6-0.6
Reaction time premature initiation rate0.20.30.7-0.6-0.8-0.6-0.7-0.6-0.6-0.4-0.6-0.1-0.40.6-0.60.6-0.5-0.5-0.1-0.30.30.1-0.0
Reaction time premature initiations0.61.02.7-1.3-1.7-1.3-0.9-0.8-1.4-1.1-1.0-0.6-0.40.5-0.50.5-1.2-0.20.4-1.41.40.9-0.9
Std. dev. reaction times0.81.53.8-1.6-1.2-1.6-1.4-1.3-1.7-1.6-1.7-1.9-1.01.0-1.01.0-1.6-0.5-0.70.1-0.20.6-0.7
Reaction time trials completed1.01.95.7-1.3-1.7-1.6-0.5-0.5-1.7-1.6-1.0-1.10.1-0.30.3-0.3-1.60.61.3-2.42.41.9-1.9
Reaction time trials AUC1.12.16.0-1.4-1.7-1.7-0.5-0.6-1.8-1.7-1.1-1.20.1-0.30.3-0.3-1.80.61.4-2.42.42.0-2.0
Run reversals in cocaine runway, females0.70.72.2-0.60.0-0.1-0.8-0.9-0.2-0.3-0.40.1-1.11.1-1.11.10.1-1.1-1.51.2-1.2-0.80.8
Run reversals in cocaine runway, males1.51.52.7-1.5-1.5-1.6-1.3-1.2-1.5-1.6-1.6-1.1-1.01.0-1.01.0-1.4-0.60.2-1.00.91.0-1.0
Latency to leave start box in cocaine runway0.40.51.90.70.50.60.60.60.70.80.81.40.8-0.80.8-0.80.80.30.10.1-0.1-0.40.4
Latency to leave start box in cocaine runway, F0.30.31.10.50.50.40.50.60.70.60.61.10.7-0.80.8-0.80.60.40.10.2-0.2-0.30.3
Latency to leave start box in cocaine runway, M0.10.10.30.2-0.1-0.10.20.2-0.1-0.10.10.60.5-0.30.3-0.30.10.10.4-0.50.60.3-0.3
Std. dev. time between licks in bursts0.91.32.7-1.6-1.6-1.3-1.5-1.5-0.9-0.9-1.0-1.1-1.31.3-1.31.3-0.6-1.2-1.0-0.60.6-0.20.2
Total sessions with >9 infusions0.81.02.5-1.5-0.9-1.2-1.3-1.2-1.6-1.3-1.3-1.1-0.40.5-0.50.5-1.3-0.7-0.90.2-0.30.6-0.7
Short access day 1 total inactive lever presses1.82.44.1-1.9-1.6-1.5-2.0-2.0-1.4-1.5-1.7-1.5-1.82.0-2.02.0-1.1-1.7-1.50.4-0.50.00.0
Short access day 10 total inactive lever presses0.61.42.7-1.2-1.7-1.4-0.9-0.9-1.1-1.2-1.3-1.5-0.70.5-0.40.4-1.5-0.20.6-1.61.61.3-1.3
Short access day 1 total infusions0.91.22.4-1.3-0.9-1.0-1.6-1.6-1.0-0.9-1.4-0.7-1.11.1-1.21.2-0.9-1.5-1.40.9-0.9-0.20.2
Short access day 10 total infusions0.40.51.2-0.9-0.5-1.0-0.9-0.9-1.0-0.9-1.1-0.6-0.3-0.00.1-0.1-1.0-0.6-0.40.4-0.50.3-0.3
Short access total infusions0.91.22.3-1.4-1.0-1.2-1.5-1.4-1.3-1.1-1.4-0.9-1.00.9-0.80.8-1.1-1.2-1.30.7-0.70.1-0.1
Short access day 1 locomotion0.30.30.8-0.8-0.2-0.6-0.7-0.7-0.8-0.6-0.7-0.9-0.30.3-0.40.4-0.7-0.5-0.70.5-0.60.4-0.4
Short access day 10 total locomotion0.20.41.1-1.0-0.9-1.0-0.8-0.7-0.8-0.8-0.7-0.8-0.2-0.10.1-0.1-0.7-0.4-0.4-0.20.30.6-0.6
Short access total locomotion0.80.92.3-1.4-1.5-1.4-1.3-1.1-1.3-1.2-1.1-1.0-0.40.3-0.30.3-1.0-0.8-0.9-0.20.20.7-0.7
One hour access (0.3 mA shock)1.11.32.6-1.6-1.6-1.6-1.2-1.1-1.6-1.6-1.4-1.4-0.10.1-0.00.0-1.6-0.5-0.1-0.90.91.1-1.1
Compulsive drug intake0.20.20.6-0.7-0.2-0.6-0.5-0.4-0.5-0.7-0.6-0.8-0.20.2-0.10.1-0.7-0.0-0.1-0.20.10.6-0.5
One hour access (shock baseline)0.20.30.6-0.7-0.7-0.6-0.8-0.8-0.6-0.6-0.6-0.6-0.40.4-0.40.4-0.3-0.8-0.60.1-0.1-0.20.2
Social response proportion0.70.82.30.20.50.6-0.3-0.40.30.50.0-0.1-1.00.9-0.90.90.6-0.8-1.21.5-1.5-1.31.3
Social responses0.40.51.4-0.20.00.1-0.5-0.6-0.10.0-0.4-0.6-1.01.2-1.21.20.0-0.9-0.70.7-0.7-0.70.7
Social time1.62.24.9-0.7-0.0-0.2-1.4-1.5-0.3-0.2-1.0-0.5-2.22.1-2.12.10.1-2.0-1.91.8-1.8-1.61.6
Soleus weight0.51.43.51.10.91.41.11.11.51.61.91.61.0-1.01.0-1.01.90.4-0.60.6-0.6-1.01.0
Bone: stiffness3.15.010.1-3.1-3.2-3.0-2.6-2.6-2.8-2.8-2.5-2.9-1.91.9-1.91.9-2.2-1.6-1.2-1.00.91.1-1.1
Tibialis anterior weight0.41.42.6-1.5-1.5-1.6-1.0-1.1-1.6-1.6-1.1-1.5-0.50.5-0.50.5-1.3-0.30.1-1.41.41.2-1.2
Time to tail flick, vehicle, before self-admin0.91.02.40.40.70.7-0.3-0.40.90.70.2-0.0-0.80.8-0.90.91.0-1.3-1.51.5-1.5-1.41.4
Time to tail flick, vehicle, after self-admin0.20.30.80.70.10.50.50.40.90.80.70.70.3-0.1-0.10.10.7-0.10.6-0.50.6-0.40.5
Time to tail flick, test, before self-admin2.42.55.61.91.11.81.81.82.32.02.32.41.2-1.11.2-1.22.11.00.8-0.20.3-1.01.0
Time to tail flick, test, after self-admin1.31.44.3-1.2-2.1-1.8-1.1-0.9-1.0-1.5-1.1-0.9-0.70.5-0.70.7-1.0-0.50.8-1.81.90.8-0.8
Delta time to tail flick, vehicle, before/after SA0.80.73.40.1-0.9-0.30.50.60.10.00.40.60.8-0.70.7-0.7-0.10.81.5-1.81.80.7-0.7
Delta time to tail flick, test, before/after SA3.33.46.1-2.2-2.0-2.1-2.5-2.3-2.2-2.1-2.3-2.0-2.21.8-2.02.0-1.5-2.0-1.60.2-0.20.2-0.2
Tibia length2.36.511.7-3.0-2.6-2.5-3.3-3.3-2.4-2.4-2.7-2.6-3.43.1-3.13.1-1.5-3.0-2.50.8-0.8-0.70.7
Ambulatory time before self-admin0.71.02.61.20.61.31.01.11.51.61.40.90.8-0.70.8-0.81.30.5-0.30.5-0.4-0.80.8
Ambulatory time after self-admin0.70.83.0-0.9-0.8-0.4-1.1-1.1-0.8-0.5-0.9-1.0-1.01.1-1.11.1-0.4-1.0-1.70.7-0.6-0.50.4
Bone: tissue strength0.10.10.3-0.3-0.5-0.2-0.3-0.3-0.1-0.10.20.1-0.50.4-0.40.40.3-0.4-0.4-0.20.2-0.30.3
Total heroin consumption0.50.61.50.3-0.00.20.70.60.50.30.60.11.2-1.21.0-1.00.00.81.2-1.21.20.7-0.7
Bone: trabecular number1.72.85.0-2.0-2.2-2.2-2.1-2.1-2.0-2.1-2.1-1.9-1.71.8-1.81.8-1.5-1.6-0.7-0.30.20.5-0.5
Bone: trabecular spacing1.21.62.91.31.21.31.61.61.31.31.21.01.6-1.71.7-1.70.51.61.2-0.60.60.3-0.4
Bone: trabecular thickness0.81.02.4-0.6-0.4-0.4-1.0-1.1-0.4-0.3-0.4-0.2-1.31.4-1.41.40.5-1.4-1.51.2-1.2-1.01.0
Bone: trabecular tissue density2.13.16.31.41.41.32.12.11.01.01.51.12.5-2.32.3-2.30.32.52.1-1.31.31.6-1.6
Water consumed over 24 hours0.20.20.90.00.80.3-0.2-0.3-0.3-0.2-0.2-0.2-0.50.5-0.50.50.1-0.4-0.50.9-0.9-0.40.4
Number of responses in last shaping day0.80.92.0-1.2-0.4-0.6-1.2-1.4-0.8-0.6-1.1-1.0-0.70.7-0.70.7-0.7-1.3-1.41.1-1.1-0.20.1