Ndufs7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb intron excision ratio chr7_9456229_9456740 0.17 0.11 4.5e-04 0.1 0.11 0.1 0.1 2.3e-03 1.4e-03 2.4e-03 2.7e-03
2 LHb intron excision ratio chr7_9456229_9456859 0.13 0.09 3.0e-03 0.07 0.09 0.08 0.08 7.6e-03 3.5e-03 5.4e-03 5.2e-03
3 Adipose isoform ratio XM_006240972.4 0.03 0.02 4.2e-04 0.02 0.02 0.03 0.02 2.7e-03 1.1e-03 8.4e-04 1.8e-03
4 Adipose alternative TSS XM_006240972.4 0.03 0.02 1.4e-03 0.02 0.02 0.01 0.02 1.2e-03 6.0e-03 2.1e-02 3.6e-03
5 Adipose alternative TSS XM_039079405.1 0.02 0.02 5.8e-03 0.01 0.01 0.01 0.01 1.4e-02 1.2e-02 2.7e-02 1.0e-02
6 OFC intron excision ratio chr7_9456229_9456740 0.22 0.13 3.8e-05 0.2 0.17 0.18 0.18 1.5e-05 8.3e-05 4.5e-05 4.5e-05
7 OFC intron excision ratio chr7_9456229_9456859 0.2 0.13 8.1e-05 0.19 0.15 0.17 0.17 3.1e-05 1.7e-04 9.7e-05 9.1e-05
8 NAcc intron excision ratio chr7_9456229_9456859 0.09 0.05 1.3e-12 0.11 0.1 0.1 0.11 2.2e-12 3.7e-12 4.8e-12 8.9e-13
9 Eye isoform ratio XM_006240972.4 0.19 0.14 9.3e-03 0.17 0.15 0.09 0.15 1.6e-03 2.5e-03 1.7e-02 3.1e-03
10 Eye intron excision ratio chr7_9456229_9456859 0.18 0.13 9.4e-03 0.02 -0 -0.01 -0.01 1.6e-01 3.9e-01 4.7e-01 4.1e-01
11 Adipose mRNA stability Ndufs7 0.02 0.02 9.1e-03 0 0 0 0 3.1e-01 2.0e-01 2.3e-01 2.3e-01
12 Adipose intron excision ratio chr7_9456229_9456859 0.04 0.03 8.1e-04 0.02 0.02 0.02 0.02 1.3e-03 1.9e-03 1.2e-03 4.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.41.7-0.00.10.10.60.60.8-0.80.80.7-0.71.30.2
Area under the delay curve2.42.63.1-1.71.71.71.81.81.6-1.61.71.6-1.61.5-0.3
BMI with tail5.818.823.5-4.84.84.74.54.54.5-4.54.54.5-4.54.0-0.5
BMI without tail1.93.85.9-2.42.42.31.91.91.9-1.91.91.9-1.91.4-1.5
Body weight1.04.35.6-2.42.42.12.02.02.1-2.12.12.1-2.11.9-1.5
Weight adjusted by age0.30.42.6-0.80.80.50.20.20.3-0.30.40.3-0.3-0.0-1.6
Bone surface0.20.31.40.6-0.6-0.40.30.30.5-0.50.40.4-0.41.2-0.0
Bone volume0.20.31.50.5-0.5-0.50.30.30.5-0.50.50.4-0.41.2-0.5
Breakpoint value in progressive ratio session5.66.16.92.5-2.5-2.5-2.6-2.6-2.62.6-2.6-2.62.6-2.60.1
Number of licking bursts0.10.10.6-0.30.30.1-0.2-0.2-0.10.10.0-0.10.1-0.40.8
Context. condit. distance diff. score0.20.30.4-0.50.50.70.60.60.6-0.60.30.6-0.60.3-0.6
Locomotion velocity, session 10.20.30.70.8-0.8-0.7-0.4-0.4-0.50.5-0.4-0.50.5-0.10.1
Locomotion distance, session 10.20.31.70.6-0.5-0.30.20.20.1-0.10.00.2-0.20.81.3
Locomotion velocity, session 22.63.05.52.4-2.3-1.9-1.5-1.5-1.61.6-1.9-1.61.6-1.01.5
Locomotion distance, session 21.01.42.71.6-1.6-1.5-0.9-0.9-1.01.0-0.8-1.01.0-0.11.6
Locomotion velocity, session 36.07.08.12.8-2.8-2.6-2.7-2.7-2.82.8-2.9-2.82.8-2.70.3
Locomotion distance, session 30.00.00.4-0.00.00.1-0.0-0.00.0-0.0-0.10.0-0.0-0.2-0.6
Stereotopy head waving bouts, day 34.35.17.12.7-2.7-2.4-2.2-2.2-2.32.3-2.3-2.32.3-2.00.7
Stereotopy head waving duration, day 35.46.48.32.9-2.9-2.6-2.5-2.5-2.62.6-2.7-2.62.6-2.30.8
Locomotion velocity, session 71.21.38.00.7-0.7-0.8-0.8-0.8-0.80.8-0.9-0.80.8-0.8-2.8
Locomotion distance, session 70.20.21.9-0.50.50.40.10.10.1-0.10.10.1-0.1-0.1-1.4
Stereotopy head waving bouts, day 70.10.10.20.2-0.20.00.30.30.2-0.20.10.2-0.20.4-0.1
Stereotopy head waving duration, day 70.10.10.30.6-0.6-0.4-0.1-0.1-0.10.1-0.1-0.10.10.2-0.3
Locomotion velocity, session 80.20.30.90.9-0.9-0.7-0.3-0.3-0.40.4-0.4-0.40.40.20.2
Locomotion distance, session 80.10.10.50.6-0.6-0.3-0.2-0.2-0.20.2-0.4-0.20.20.00.7
Degree of sensitization distance0.30.40.4-0.70.70.60.60.60.6-0.60.60.6-0.60.6-0.3
Degree of sensitization stereotypy2.22.42.9-1.41.41.41.61.61.7-1.71.61.7-1.71.7-0.6
Conditioned locomotion0.91.02.0-1.41.41.31.01.00.9-0.91.10.9-0.90.60.0
Cocaine response after cond. corrected3.84.37.1-2.72.62.62.12.11.9-1.91.92.0-2.01.4-1.0
Cocaine response after cond. not corrected4.04.47.3-2.72.72.62.12.11.9-1.91.92.1-2.11.4-1.1
Cocaine response before conditioning0.40.50.70.8-0.8-0.8-0.7-0.7-0.70.7-0.7-0.70.7-0.6-0.6
Saline control response0.00.00.2-0.30.30.20.10.10.1-0.10.20.2-0.20.10.5
Bone: connectivity density0.50.91.9-0.40.50.61.01.01.1-1.11.01.1-1.11.40.5
Bone: cortical apparent density0.81.01.4-1.11.11.01.01.01.1-1.11.21.0-1.00.90.4
Bone: cortical area0.81.21.8-0.90.90.91.11.11.2-1.21.21.1-1.11.3-0.9
Bone: cortical porosity0.30.40.70.8-0.8-0.9-0.6-0.6-0.60.6-0.5-0.60.6-0.3-0.3
Bone: cortical porosity0.00.00.30.2-0.2-0.20.10.10.2-0.20.20.1-0.10.50.0
Bone: cortical thickness1.22.02.6-1.41.41.31.51.51.5-1.51.61.4-1.41.6-0.3
Bone: cortical thickness0.10.21.3-0.20.1-0.0-0.3-0.3-0.30.3-0.1-0.30.3-0.5-1.1
Bone: cortical tissue density0.50.70.9-0.90.90.80.80.80.9-0.91.00.9-0.90.70.3
Condit. Reinf. active minus inactive responses4.04.55.92.4-2.4-2.2-2.1-2.1-2.12.1-2.4-2.22.2-2.10.6
Condit. Reinf. active-inactive response ratio2.32.53.41.6-1.6-1.5-1.6-1.6-1.61.6-1.8-1.71.7-1.80.2
Condit. Reinf. active responses3.13.75.62.4-2.4-2.1-1.9-1.9-1.81.8-2.1-1.91.9-1.51.2
Condit. Reinf. inactive responses0.50.61.31.1-1.1-1.0-0.6-0.6-0.60.6-0.6-0.60.6-0.11.2
Incentive salience index mean1.82.23.51.9-1.9-1.6-1.4-1.4-1.41.4-1.7-1.41.4-1.20.8
Condit. Reinf. lever presses0.20.20.90.3-0.2-0.10.40.40.4-0.40.30.3-0.30.90.9
Condit. Reinf. active minus inactive responses2.42.93.91.5-1.5-1.7-1.9-1.9-1.91.9-1.6-1.91.9-2.0-0.4
Condit. Reinf. active-inactive response ratio0.30.30.80.1-0.1-0.3-0.6-0.6-0.60.6-0.2-0.60.6-0.80.9
Condit. Reinf. active responses2.12.93.41.6-1.6-1.8-1.8-1.8-1.81.8-1.4-1.81.8-1.8-1.3
Condit. Reinf. inactive responses1.21.53.81.1-1.1-1.2-1.1-1.1-1.21.2-1.0-1.11.1-1.1-1.9
Condit. Reinf. lever presses2.53.44.31.7-1.7-1.8-2.0-2.0-2.12.1-1.8-2.02.0-2.0-0.3
Condit. Reinf. lever reinforcers received1.72.43.01.3-1.3-1.5-1.7-1.7-1.71.7-1.3-1.61.6-1.7-1.4
Conditioned reinforcement - actives2.32.33.31.5-1.5-1.8-1.7-1.7-1.41.4-1.4-1.41.4-1.3-1.4
Conditioned reinforcement - inactives0.30.30.5-0.70.70.70.50.50.6-0.60.50.6-0.60.3-0.5
Conditioned locomotion6.78.010.03.0-3.0-3.2-3.1-3.1-2.92.9-2.9-2.92.9-2.7-0.3
Patch foraging indifference point 0 sec0.10.20.4-0.50.50.30.40.40.5-0.50.50.5-0.50.6-0.6
Patch foraging indifference point AUC0.91.01.21.0-1.0-1.1-1.1-1.1-1.01.0-1.0-1.01.0-1.00.3
Delay disc. indifference point, 0s delay7.98.712.3-2.72.72.73.13.13.2-3.23.23.2-3.23.5-0.1
Delay disc. indifference point, 16s delay0.20.20.5-0.30.30.50.50.50.4-0.40.30.4-0.40.30.7
Delay disc. indifference point, 2s delay6.26.87.8-2.62.62.52.72.72.8-2.82.82.8-2.82.7-1.3
Delay disc. indifference point, 24s delay0.70.71.1-1.01.01.00.90.90.7-0.70.80.7-0.70.7-0.8
Delay disc. indifference point, 4s delay1.31.41.9-1.01.01.31.41.41.2-1.21.11.2-1.21.20.0
Delay disc. indifference point, 8s delay1.11.11.7-1.31.31.21.11.11.0-1.01.11.0-1.00.8-0.1
Indifference point function ln k0.30.41.0-0.60.60.70.60.60.5-0.50.50.6-0.60.4-1.0
Indifference point function log k0.30.41.0-0.60.60.70.60.60.5-0.50.50.6-0.60.4-1.0
Patch foraging total patch changes 0 sec0.10.20.3-0.40.40.30.30.30.4-0.40.40.4-0.40.4-0.5
Patch foraging total patch changes 12 sec0.10.20.5-0.70.70.50.30.30.4-0.40.40.4-0.40.30.3
Patch foraging total patch changes 18 sec1.11.41.71.2-1.2-1.3-1.3-1.3-1.21.2-1.3-1.21.2-1.10.3
Patch foraging total patch changes 24 sec0.10.10.20.3-0.3-0.5-0.4-0.4-0.30.3-0.2-0.30.3-0.20.1
Patch foraging total patch changes 6 sec0.20.30.60.6-0.6-0.7-0.6-0.6-0.50.5-0.4-0.60.6-0.40.2
Patch foraging time to switch 0 sec1.52.34.0-1.11.11.31.71.71.6-1.61.51.6-1.62.01.2
Patch foraging water rate 0 sec0.20.32.3-0.20.2-0.0-0.4-0.4-0.30.3-0.3-0.30.3-0.9-1.5
Patch foraging water rate 12 sec0.61.02.1-1.51.41.30.80.80.7-0.70.90.8-0.80.2-1.0
Patch foraging water rate 18 sec0.50.62.4-0.10.0-0.2-0.8-0.8-0.90.9-0.7-0.80.8-1.5-0.6
Patch foraging water rate 24 sec0.20.20.8-0.90.90.70.10.10.0-0.00.10.1-0.1-0.7-0.3
Patch foraging water rate 6 sec0.60.81.90.3-0.4-0.5-1.0-1.0-1.01.0-0.8-1.01.0-1.4-0.9
Seeking ratio, delayed vs. immediate footshock3.74.35.52.3-2.3-2.4-2.2-2.2-2.12.1-2.1-2.12.1-1.8-0.2
Distance traveled before self-admin0.60.60.9-0.70.70.60.70.70.9-0.90.90.9-0.91.0-0.5
Distance traveled after self-admin0.60.71.10.8-0.8-1.0-0.9-0.9-0.80.8-0.7-0.70.7-0.5-1.1
Extensor digitorum longus weight4.015.720.9-4.64.64.54.14.14.1-4.13.94.1-4.13.4-0.5
Bone: elastic displacement0.20.20.30.5-0.5-0.6-0.5-0.5-0.50.5-0.4-0.50.5-0.4-0.4
Bone: elastic work0.40.52.0-0.60.60.50.60.60.6-0.60.60.6-0.60.6-1.4
Bone: endosteal estimation0.20.50.6-0.60.60.70.80.80.8-0.80.60.8-0.80.7-0.2
Bone: endosteal perimeter0.10.30.50.7-0.7-0.6-0.4-0.4-0.50.5-0.6-0.40.4-0.3-0.6
Epididymis fat weight0.40.94.20.8-0.8-0.6-0.8-0.8-0.80.8-0.9-0.80.8-0.92.0
Delta time in closed arm before/after self-admin0.30.31.0-1.01.00.70.20.20.4-0.40.40.4-0.4-0.2-0.7
Delta time in open arm before/after self-admin1.31.31.6-1.11.11.21.31.31.1-1.11.21.1-1.11.21.0
Diff in mean of infusions in LGA sessions1.82.02.51.6-1.6-1.3-1.3-1.3-1.51.5-1.5-1.41.4-1.40.9
Delay discount exponential model param2.22.32.81.6-1.6-1.7-1.7-1.7-1.51.5-1.6-1.51.5-1.40.4
Extinction: sum of active levers before priming1.51.52.11.1-1.1-1.3-1.5-1.5-1.21.2-1.2-1.21.2-1.4-0.4
Active lever presses in extinction session 62.72.63.71.6-1.6-1.9-1.8-1.8-1.61.6-1.5-1.61.6-1.3-1.4
Bone: final force1.42.32.9-1.51.51.51.61.61.6-1.61.61.6-1.61.7-0.6
Bone: final moment1.11.82.3-1.31.41.31.41.41.4-1.41.41.4-1.41.5-0.6
Food consumed during 24 hour testing period0.60.71.0-0.90.90.80.70.71.0-1.00.70.9-0.90.6-0.6
Glucose1.32.02.6-1.61.61.51.41.41.4-1.41.61.5-1.51.3-0.6
Heart weight0.40.60.90.6-0.6-0.6-0.8-0.8-0.80.8-0.7-0.90.9-0.90.2
Delay discount hyperbolic model param3.13.23.71.9-1.9-1.9-1.9-1.9-1.91.9-1.9-1.81.8-1.70.6
Intermittent access intake day 1-15 change6.86.88.02.6-2.6-2.8-2.8-2.8-2.72.7-2.7-2.72.7-2.6-1.0
Intermittent access intake escalation7.17.08.62.4-2.5-2.8-2.9-2.9-2.72.7-2.7-2.72.7-2.8-1.1
Intermittent access intake escalation 28.68.510.02.7-2.7-2.9-3.2-3.2-3.13.1-3.0-3.13.1-3.1-0.6
Intermitt. access day 1 inactive lever presses0.40.42.30.2-0.2-0.5-0.7-0.7-0.50.5-0.5-0.50.5-0.7-1.5
Intermitt. access day 15 inactive lever presses0.60.60.80.7-0.7-0.7-0.8-0.8-0.90.9-0.8-0.90.9-0.9-0.1
Intermitt. access escalation Index0.50.40.7-0.40.40.40.70.70.8-0.80.60.8-0.80.8-0.1
Intermittent access day 1 total infusions0.00.10.2-0.20.20.20.20.20.2-0.20.20.2-0.20.3-0.4
Intermittent access day 15 total infusions2.32.63.21.5-1.5-1.7-1.8-1.8-1.71.7-1.6-1.71.7-1.7-1.0
Intermittent access terminal intake (last 3 days)1.31.52.01.1-1.1-1.3-1.3-1.3-1.21.2-1.1-1.21.2-1.1-1.4
Intermittent access total infusions0.30.41.00.5-0.5-0.6-0.7-0.7-0.50.5-0.5-0.50.5-0.6-1.0
Intermittent access day 1 locomotion0.40.40.50.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.70.7-0.70.0
Intermittent access day 15 total locomotion3.63.94.52.1-2.1-2.1-2.1-2.1-2.02.0-2.1-2.02.0-1.90.2
Intermittent access total locomotion0.91.11.61.1-1.1-1.3-1.2-1.2-1.01.0-1.0-1.01.0-0.9-0.6
Intermittent access standard deviation3.23.34.11.6-1.6-1.8-2.0-2.0-1.91.9-1.8-1.91.9-1.9-1.1
Left kidney weight0.00.10.50.2-0.2-0.3-0.1-0.1-0.10.1-0.2-0.10.10.2-0.7
Right kidney weight1.33.64.42.0-2.0-2.1-2.0-2.0-2.02.0-2.1-2.02.0-1.7-0.6
Cocaine induced anxiety0.40.40.90.8-0.8-0.9-0.6-0.6-0.70.7-0.4-0.70.7-0.1-0.3
Post-drug Anxiety0.30.40.70.8-0.8-0.5-0.3-0.3-0.70.7-0.4-0.70.7-0.00.8
Baseline Anxiety0.30.41.30.3-0.40.0-0.3-0.3-0.60.6-0.6-0.60.6-0.81.1
Tail length3.19.410.93.1-3.1-3.1-3.2-3.2-3.33.3-3.3-3.23.2-3.1-0.7
Length with tail1.76.47.92.7-2.7-2.8-2.7-2.7-2.62.6-2.6-2.52.5-2.2-1.1
Length without tail0.00.10.30.4-0.4-0.5-0.2-0.2-0.00.0-0.10.0-0.00.3-0.5
Times rat made contact with spout0.10.10.3-0.60.50.50.30.30.3-0.30.30.3-0.3-0.0-0.0
Lifetime Intake0.10.20.70.3-0.3-0.4-0.5-0.5-0.30.3-0.3-0.30.3-0.3-0.8
Liver weight, left2.03.24.1-2.02.02.01.81.81.8-1.81.81.8-1.81.61.1
Liver weight, right1.62.73.1-1.61.71.71.81.81.7-1.71.61.7-1.71.70.9
Locomotor activity2.53.95.92.3-2.3-2.4-2.1-2.1-2.02.0-1.9-2.02.0-1.3-0.5
Locomotor testing distance1.62.63.71.8-1.8-1.9-1.7-1.7-1.71.7-1.6-1.71.7-1.2-0.3
Locomotor testing rearing0.10.10.30.0-0.0-0.1-0.3-0.3-0.40.4-0.2-0.40.4-0.5-0.5
Locomotion in novel chamber0.30.40.60.4-0.4-0.7-0.8-0.8-0.60.6-0.5-0.60.6-0.70.4
Locomotion in novel chamber post-restriction0.91.01.51.0-1.0-1.0-1.1-1.1-1.01.0-1.1-1.01.0-1.2-0.6
Fecal boli incidents, locomotor time 11.41.52.1-1.41.41.21.11.11.2-1.21.41.2-1.21.10.7
Change in fecal boli incidents, locomotor task1.61.516.90.3-0.3-0.5-0.4-0.4-0.30.3-0.3-0.30.3-0.1-4.1
Time >=10cm from walls, locomotor time 10.70.71.8-0.80.80.50.70.70.7-0.71.00.7-0.71.3-1.3
Bouts of movement, locomotor time 10.20.20.30.4-0.4-0.4-0.5-0.5-0.50.5-0.4-0.50.5-0.5-0.3
Total resting periods, locomotor time 10.30.30.30.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5
Rest time, locomotor task time 10.20.20.40.6-0.6-0.5-0.4-0.4-0.30.3-0.5-0.30.3-0.30.3
Distance moved, locomotor task time 10.91.03.9-0.80.80.70.90.90.8-0.81.00.8-0.81.2-2.0
Vertical activity count, locomotor time 10.40.54.6-0.60.60.30.20.20.2-0.20.30.2-0.20.1-2.1
Time >=10cm from walls, locomotor time 21.21.22.1-1.41.41.11.01.01.0-1.01.31.0-1.01.0-1.1
Bouts of movement, locomotor time 20.40.42.00.8-0.8-0.6-0.4-0.4-0.30.3-0.5-0.30.3-0.11.4
Total resting periods, locomotor time 20.40.42.30.8-0.8-0.5-0.3-0.3-0.30.3-0.4-0.30.3-0.11.5
Rest time, locomotor task time 20.40.50.80.9-0.9-0.7-0.6-0.6-0.70.7-0.6-0.70.7-0.40.4
Distance moved, locomotor task time 20.60.61.0-1.01.00.90.80.80.8-0.80.80.8-0.80.60.1
Vertical activity count, locomotor time 20.40.51.0-1.01.00.80.50.50.7-0.70.60.7-0.70.3-0.5
Light reinforcement 15.49.912.83.6-3.6-3.5-3.2-3.2-3.23.2-3.2-3.23.2-2.71.2
Light reinforcement 21.82.43.31.8-1.8-1.7-1.5-1.5-1.51.5-1.5-1.61.6-1.30.7
Bone: marrow area0.20.50.7-0.60.60.70.80.80.8-0.80.60.8-0.80.7-0.2
Bone: maximum diameter0.40.71.31.2-1.1-1.1-0.8-0.8-0.80.8-0.8-0.80.8-0.4-0.5
Bone: maximum force1.32.32.6-1.61.61.51.61.61.5-1.51.51.5-1.51.6-0.8
Bone: maximum moment1.11.92.1-1.41.41.41.51.51.4-1.41.41.4-1.41.4-0.8
Mean time between licks in bursts4.36.07.02.5-2.5-2.5-2.6-2.6-2.62.6-2.4-2.62.6-2.51.0
Mean num. licks in bursts0.10.10.9-0.10.10.20.30.30.3-0.30.10.3-0.30.3-0.9
Cd content in liver0.30.30.8-0.60.60.40.50.50.5-0.50.90.5-0.50.6-0.0
Co content in liver0.50.60.80.8-0.8-0.7-0.7-0.7-0.90.9-0.7-0.80.8-0.80.7
Cu content in liver0.30.30.8-0.30.30.40.70.70.5-0.50.70.6-0.60.90.1
Fe content in liver0.10.10.20.2-0.2-0.2-0.3-0.3-0.30.3-0.3-0.20.2-0.40.1
K content in liver0.20.21.10.00.00.20.50.50.3-0.30.40.4-0.40.71.0
Mg content in liver0.20.20.6-0.00.10.20.60.60.3-0.30.50.4-0.40.80.7
Mn content in liver0.40.41.21.1-1.1-0.9-0.4-0.4-0.50.5-0.6-0.40.40.2-0.6
Na content in liver1.31.32.3-0.90.90.91.11.11.3-1.31.21.4-1.41.50.5
Rb content in liver0.60.81.5-0.60.60.71.01.01.0-1.01.01.0-1.01.20.1
Se content in liver0.10.20.30.6-0.6-0.4-0.3-0.3-0.30.3-0.6-0.20.2-0.30.6
Sr content in liver0.20.10.40.0-0.0-0.3-0.6-0.6-0.20.2-0.3-0.20.2-0.5-0.5
Zn content in liver2.22.54.31.3-1.3-1.4-1.7-1.7-1.71.7-1.8-1.71.7-2.10.8
Bone: minimum diameter0.10.10.5-0.10.10.10.30.30.3-0.30.10.3-0.30.4-0.7
Time in familiar zone, hab. session 12.62.43.11.5-1.5-1.4-1.6-1.6-1.81.8-1.7-1.71.7-1.7-0.1
Time in novel zone, hab. session 11.51.52.1-1.01.00.91.21.21.3-1.31.31.3-1.31.4-1.2
Total zone transitions, hab. session 10.60.81.61.3-1.3-1.1-0.7-0.7-0.80.8-0.8-0.80.8-0.20.9
Total locomotion distance, hab. session 10.50.71.91.4-1.4-1.1-0.6-0.6-0.80.8-0.8-0.70.70.00.2
Locomotion velocity, hab. session 11.01.32.81.7-1.6-1.4-1.0-1.0-1.11.1-1.1-1.11.1-0.31.0
Time in familiar zone, hab. session 26.87.18.72.7-2.7-2.5-2.8-2.8-2.82.8-2.9-2.82.8-3.00.2
Time in novel zone, hab. session 25.35.36.5-2.32.32.22.42.42.4-2.42.52.4-2.42.5-0.8
Total zone transitions, hab. session 20.60.83.4-0.10.10.30.80.80.7-0.70.80.8-0.81.51.8
Total locomotion distance, hab. session 20.81.03.11.4-1.3-1.1-0.7-0.7-0.90.9-0.9-0.80.8-0.21.8
Locomotion velocity, hab. session 20.71.03.81.4-1.3-1.1-0.6-0.6-0.70.7-0.7-0.70.70.02.0
Novel to familiar place preference ratio4.95.06.8-2.12.12.02.32.32.4-2.42.42.4-2.42.6-1.1
Novelty place preference3.13.14.5-1.61.61.51.91.91.9-1.91.81.9-1.92.1-0.9
Time in novel zone, NPP test3.43.54.6-1.71.81.72.02.02.0-2.01.92.0-2.02.2-1.0
Total zone transitions, NPP test0.40.54.90.2-0.2-0.00.30.30.2-0.20.30.2-0.20.82.2
Total locomotion distance, NPP test0.20.31.20.1-0.10.10.50.50.3-0.30.30.4-0.40.91.1
Locomotion velocity, NPP test0.10.21.70.4-0.4-0.20.20.20.0-0.00.10.1-0.10.61.3
Intraocular pressure0.20.20.9-0.00.0-0.1-0.5-0.5-0.50.5-0.5-0.50.5-0.90.4
Delta distance traveled before/after self-admin1.71.92.21.5-1.5-1.4-1.4-1.4-1.51.5-1.4-1.51.5-1.3-0.5
Delta ambulatory time before/after self-admin1.71.92.41.5-1.5-1.5-1.4-1.4-1.41.4-1.4-1.41.4-1.2-0.4
Parametrial fat weight0.51.01.50.8-0.8-0.9-1.0-1.0-1.01.0-1.0-1.01.0-1.0-1.2
Pavlov. Cond. lever latency0.10.10.4-0.10.1-0.0-0.4-0.4-0.30.3-0.1-0.30.3-0.7-0.2
Pavlov. Cond. magazine entry latency3.14.05.22.2-2.2-2.0-2.0-2.0-2.02.0-2.3-2.02.0-2.00.9
Pavlov. Cond. change in total contacts0.10.10.20.4-0.4-0.3-0.2-0.2-0.20.2-0.4-0.20.2-0.10.4
Pavlov. Cond. index score0.30.40.90.9-0.9-0.7-0.5-0.5-0.50.5-0.9-0.60.6-0.30.5
Pavlov. Cond. latency score0.30.30.80.9-0.9-0.7-0.4-0.4-0.40.4-0.7-0.50.5-0.10.3
Pavlov. Cond. lever contacts0.10.10.30.3-0.3-0.20.20.20.2-0.2-0.00.1-0.10.60.2
Pavlov. Cond. magazine entry number0.80.91.4-1.11.10.90.90.90.9-0.91.21.0-1.00.9-0.7
Pavlov. Cond. intertrial magazine entries0.20.30.60.3-0.3-0.3-0.6-0.6-0.50.5-0.4-0.50.5-0.80.6
Pavlov. Cond. lever-magazine prob. diff.0.70.81.41.2-1.2-1.0-0.8-0.8-0.80.8-1.1-0.90.9-0.60.4
Pavlov. Cond. response bias1.11.41.91.4-1.4-1.2-1.1-1.1-1.11.1-1.4-1.21.2-1.10.7
Pavlov. Cond. lever latency0.91.23.1-0.90.91.01.11.11.2-1.20.81.1-1.11.01.8
Pavlov. Cond. magazine entry latency0.50.61.60.7-0.7-0.7-0.7-0.7-0.70.7-0.9-0.70.7-0.7-1.3
Pavlov. Cond. change in total contacts0.81.01.30.8-0.8-1.0-1.1-1.1-1.11.1-0.8-1.11.1-1.0-1.1
Pavlov. Cond. index score1.01.32.90.9-0.9-1.0-1.1-1.1-1.21.2-1.0-1.21.2-1.1-1.7
Pavlov. Cond. latency score0.91.12.80.9-0.9-1.0-1.0-1.0-1.11.1-0.9-1.11.1-0.9-1.7
Pavlov. Cond. lever contacts0.91.32.50.8-0.8-1.0-1.1-1.1-1.21.2-0.9-1.21.2-1.1-1.6
Pavlov. Cond. magazine entry number0.70.91.6-0.90.90.90.90.91.0-1.01.00.9-0.90.91.3
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.70.70.60.40.40.4-0.40.60.4-0.40.2-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.22.50.9-0.9-1.0-1.1-1.1-1.21.2-1.0-1.11.1-1.0-1.6
Pavlov. Cond. response bias2.02.73.21.4-1.4-1.5-1.7-1.7-1.81.8-1.5-1.71.7-1.7-1.6
Time in closed arm before self-admin1.11.22.1-0.70.80.81.21.21.2-1.21.11.2-1.21.50.9
Time in closed arm after self-admin0.00.00.10.1-0.1-0.2-0.2-0.2-0.10.1-0.2-0.10.1-0.20.2
Time in open arm before self-admin0.91.02.30.8-0.8-1.0-1.1-1.1-0.90.9-0.9-0.90.9-1.0-1.5
Time in open arm after self-admin0.80.81.0-1.01.01.01.01.00.9-0.90.90.9-0.90.80.3
Bone: periosteal estimation0.50.91.4-0.80.80.81.11.11.1-1.11.01.0-1.01.2-0.5
Bone: periosteal perimeter0.00.10.50.3-0.2-0.20.00.00.0-0.00.0-0.00.00.3-0.7
Bone: post-yield work0.50.60.9-0.90.91.00.80.80.8-0.80.70.8-0.80.6-0.1
Progressive ratio test 1 active lever presses0.00.00.2-0.20.20.20.10.10.2-0.20.00.2-0.2-0.1-0.4
Progressive ratio test 1 breakpoint0.10.10.2-0.40.40.30.20.20.3-0.30.20.3-0.30.0-0.4
Progressive ratio test 1 inactive lever presses0.00.00.00.2-0.2-0.2-0.1-0.1-0.00.0-0.2-0.00.0-0.1-0.1
Progressive ratio test 2 active lever presses0.40.41.60.3-0.3-0.5-0.7-0.7-0.50.5-0.5-0.50.5-0.7-1.3
Progressive ratio test 2 breakpoint0.40.41.40.4-0.4-0.6-0.7-0.7-0.50.5-0.5-0.50.5-0.6-1.2
Progressive ratio test 2 inactive lever presses0.10.10.60.2-0.2-0.4-0.3-0.3-0.20.2-0.1-0.20.2-0.0-0.7
Incentive Sensitization - Responses0.40.42.20.2-0.2-0.6-0.7-0.7-0.40.4-0.4-0.40.4-0.6-1.5
Incentive Sensitization - Breakpoint0.40.41.80.3-0.3-0.6-0.7-0.7-0.50.5-0.5-0.50.5-0.6-1.3
Sum of active levers in priming session hrs 5-60.00.00.00.00.0-0.1-0.0-0.00.0-0.00.10.0-0.00.1-0.1
Progressive ratio0.50.66.0-0.40.40.60.40.40.3-0.30.10.3-0.30.22.4
Food seeking constrained by brief footshock0.50.65.00.7-0.7-0.5-0.4-0.4-0.30.3-0.5-0.30.3-0.22.2
Seeking ratio, punishment vs. effort0.10.10.30.6-0.6-0.6-0.4-0.4-0.30.3-0.2-0.20.2-0.2-0.4
Retroperitoneal fat weight0.20.71.1-0.90.91.10.90.90.9-0.90.60.9-0.90.60.9
Reaction time number correct0.40.51.0-1.01.00.90.50.50.7-0.70.60.6-0.6-0.0-0.9
Reaction time mean minus median0.60.91.20.8-0.8-0.8-0.9-0.9-1.11.1-1.0-1.01.0-1.0-0.4
Reaction time mean minus median AUC0.10.10.40.0-0.00.10.20.20.1-0.10.10.2-0.20.4-0.6
Reaction time num false alarms0.30.44.4-0.50.50.30.10.10.2-0.20.00.1-0.1-0.2-2.1
Reaction time num false alarms AUC0.30.43.5-0.60.60.40.10.10.2-0.20.10.2-0.2-0.3-1.9
Reaction time trials correct on left0.40.51.0-1.01.00.90.50.50.7-0.70.60.6-0.6-0.0-0.9
Reaction time trials on left0.40.51.0-1.01.00.90.60.60.7-0.70.60.7-0.70.0-0.9
Reaction time mean0.10.10.7-0.20.20.10.20.20.0-0.00.20.1-0.10.3-0.9
Reaction time mean AUC0.10.10.9-0.20.20.20.30.30.1-0.10.30.2-0.20.4-0.9
Median of all reaction times0.30.50.7-0.60.60.60.70.70.6-0.60.70.7-0.70.8-0.8
Reaction time omissions0.20.20.40.6-0.6-0.6-0.5-0.5-0.40.4-0.4-0.40.4-0.30.4
Reaction time false alarm rate0.10.21.7-0.20.20.10.10.10.1-0.10.00.1-0.10.1-1.3
Reaction time premature initiation rate1.31.72.21.2-1.2-1.2-1.4-1.4-1.51.5-1.3-1.51.5-1.50.5
Reaction time premature initiations0.91.22.60.7-0.7-0.8-1.2-1.2-1.21.2-1.1-1.21.2-1.6-0.0
Std. dev. reaction times0.20.20.40.4-0.4-0.4-0.4-0.4-0.60.6-0.4-0.50.5-0.4-0.6
Reaction time trials completed0.40.51.0-1.01.00.90.60.60.7-0.70.60.7-0.70.0-0.9
Reaction time trials AUC0.30.50.9-1.01.00.90.50.50.6-0.60.50.6-0.6-0.2-0.9
Run reversals in cocaine runway, females0.30.30.50.7-0.7-0.6-0.5-0.5-0.50.5-0.7-0.50.5-0.4-0.2
Run reversals in cocaine runway, males1.21.21.81.3-1.3-1.2-1.1-1.1-1.01.0-1.1-1.01.0-1.00.9
Latency to leave start box in cocaine runway0.70.72.80.8-0.8-1.1-0.8-0.8-0.70.7-0.3-0.70.7-0.1-1.7
Latency to leave start box in cocaine runway, F0.70.75.7-0.20.2-0.30.20.20.4-0.40.90.5-0.51.1-2.4
Latency to leave start box in cocaine runway, M3.13.04.01.6-1.6-1.6-1.8-1.8-1.91.9-1.8-1.91.9-2.00.2
Std. dev. time between licks in bursts0.70.82.50.9-0.9-0.9-0.8-0.8-0.90.9-0.5-0.80.8-0.6-1.6
Total sessions with >9 infusions0.30.43.9-0.10.1-0.2-0.1-0.10.3-0.30.30.3-0.30.4-2.0
Short access day 1 total inactive lever presses0.10.10.20.3-0.3-0.4-0.3-0.3-0.10.1-0.3-0.10.1-0.20.3
Short access day 10 total inactive lever presses0.00.00.1-0.00.0-0.2-0.2-0.2-0.20.2-0.0-0.20.2-0.1-0.3
Short access day 1 total infusions0.10.10.30.5-0.5-0.5-0.3-0.3-0.20.2-0.2-0.20.20.0-0.2
Short access day 10 total infusions0.10.10.40.1-0.1-0.2-0.3-0.3-0.10.1-0.3-0.10.1-0.4-0.6
Short access total infusions0.10.10.7-0.00.0-0.2-0.1-0.10.1-0.10.00.1-0.10.1-0.8
Short access day 1 locomotion0.90.91.41.1-1.1-1.2-1.0-1.0-0.90.9-0.9-0.90.9-0.6-1.2
Short access day 10 total locomotion4.04.56.02.1-2.1-2.4-2.5-2.5-2.02.0-2.2-2.02.0-2.1-1.3
Short access total locomotion1.01.02.30.9-0.9-1.2-1.1-1.1-0.80.8-0.9-0.80.8-0.8-1.5
One hour access (0.3 mA shock)0.10.20.2-0.40.40.40.40.40.4-0.40.30.4-0.40.3-0.4
Compulsive drug intake1.51.52.0-1.21.21.21.31.31.3-1.31.41.3-1.31.40.0
One hour access (shock baseline)0.20.20.50.3-0.3-0.3-0.5-0.5-0.40.4-0.5-0.40.4-0.7-0.6
Social response proportion0.70.83.01.0-1.0-0.9-0.7-0.7-0.70.7-0.5-0.80.8-0.41.7
Social responses5.77.49.43.1-3.0-3.0-2.8-2.8-2.92.9-2.6-2.82.8-2.30.0
Social time0.60.82.0-0.80.80.80.80.80.7-0.71.00.8-0.80.91.4
Soleus weight8.525.029.5-5.45.45.35.25.25.2-5.25.25.2-5.24.7-1.0
Bone: stiffness3.14.85.5-2.32.32.32.32.32.3-2.32.32.3-2.32.2-0.4
Tibialis anterior weight1.24.04.8-2.12.12.12.12.12.2-2.22.02.1-2.11.8-0.6
Time to tail flick, vehicle, before self-admin0.20.20.50.7-0.7-0.6-0.4-0.4-0.30.3-0.4-0.40.4-0.10.7
Time to tail flick, vehicle, after self-admin0.50.52.40.3-0.4-0.1-0.4-0.4-0.60.6-0.6-0.60.6-0.91.5
Time to tail flick, test, before self-admin0.10.10.20.5-0.5-0.4-0.2-0.2-0.20.2-0.2-0.20.20.10.3
Time to tail flick, test, after self-admin0.40.42.80.6-0.6-0.4-0.2-0.2-0.30.3-0.4-0.30.3-0.31.7
Delta time to tail flick, vehicle, before/after SA0.20.10.5-0.60.60.70.30.30.1-0.10.20.2-0.2-0.30.5
Delta time to tail flick, test, before/after SA0.30.20.60.4-0.4-0.3-0.5-0.5-0.40.4-0.6-0.50.5-0.70.7
Tibia length0.92.63.51.6-1.6-1.6-1.6-1.6-1.91.9-1.7-1.71.7-1.60.1
Ambulatory time before self-admin0.50.50.7-0.70.70.50.60.60.8-0.80.80.8-0.80.8-0.6
Ambulatory time after self-admin0.30.30.70.6-0.6-0.7-0.6-0.6-0.50.5-0.5-0.50.5-0.3-0.8
Bone: tissue strength1.81.72.0-1.31.41.31.41.41.3-1.31.41.3-1.31.40.7
Total heroin consumption1.82.12.71.6-1.6-1.6-1.5-1.5-1.51.5-1.5-1.51.5-1.40.0
Bone: trabecular number0.30.41.11.0-1.0-0.9-0.6-0.6-0.50.5-0.6-0.50.5-0.1-0.1
Bone: trabecular spacing0.10.20.8-0.90.80.70.10.10.0-0.00.10.1-0.1-0.5-0.1
Bone: trabecular thickness0.50.62.70.00.0-0.00.70.70.7-0.70.90.8-0.81.6-0.4
Bone: trabecular tissue density1.41.92.4-1.61.61.51.41.41.3-1.31.41.3-1.31.11.6
Water consumed over 24 hours0.81.01.3-0.90.90.81.01.01.1-1.11.11.0-1.01.1-1.2
Number of responses in last shaping day0.40.43.20.3-0.3-0.6-0.5-0.5-0.30.3-0.4-0.30.3-0.3-1.8