Hub : Genes

Ndufs7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_006240972.5 0.03 0.02 1.2e-03 0.01 0.02 0.02 0.02 1.0e-02 3.5e-03 6.4e-03 4.8e-03
2 LHb intron excision ratio chr7_10106899_10107529 0.13 0.09 3.9e-03 0.08 0.09 0.08 0.08 6.9e-03 4.7e-03 6.3e-03 7.3e-03
3 LHb intron excision ratio chr7_10106899_10107410 0.18 0.12 3.7e-04 0.11 0.12 0.1 0.1 1.7e-03 1.1e-03 1.8e-03 2.1e-03
4 Adipose alternative TSS NM_001008525.1 0.02 0.02 7.5e-03 0.01 0.01 0 0 3.7e-02 5.5e-02 1.4e-01 1.1e-01
5 Adipose alternative TSS XM_039079404.1 0.02 0.02 6.3e-03 0.02 0.01 0.01 0.01 3.5e-03 1.7e-02 5.3e-02 6.8e-03
6 Eye alternative TSS NM_001008525.1 0.36 0.22 5.5e-03 0.1 0.07 0.07 0.08 1.2e-02 3.2e-02 3.3e-02 2.4e-02
7 OFC intron excision ratio chr7_10106899_10107410 0.21 0.13 7.7e-05 0.17 0.14 0.16 0.15 9.2e-05 3.4e-04 1.5e-04 1.7e-04
8 Eye intron excision ratio chr7_10106899_10107529 0.17 0.13 9.2e-03 0.03 -0 -0.01 -0 1.1e-01 3.6e-01 5.9e-01 3.4e-01
9 OFC intron excision ratio chr7_10106899_10107529 0.2 0.13 1.5e-04 0.15 0.12 0.14 0.14 2.0e-04 7.6e-04 2.9e-04 3.9e-04
10 Adipose intron excision ratio chr7_10106899_10107529 0.03 0.03 7.4e-04 0.02 0.02 0.01 0.02 9.1e-04 1.5e-03 8.4e-03 3.0e-03
11 Adipose mRNA stability Ndufs7 0.02 0.02 5.6e-03 0 0 0 0 2.8e-01 1.7e-01 2.8e-01 1.7e-01
12 Eye isoform ratio NM_001008525.1 0.36 0.22 9.0e-03 0.11 0.13 0.07 0.11 8.4e-03 5.8e-03 3.5e-02 9.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.72.90.00.1-0.10.7-0.70.7-0.70.80.80.71.31.7
Area under the delay curve2.22.52.8-1.61.6-1.61.7-1.71.7-1.71.51.51.71.51.3
BMI with tail6.020.624.3-4.94.9-4.94.5-4.54.5-4.54.74.74.64.13.4
BMI without tail1.75.07.1-2.72.6-2.62.2-2.22.2-2.22.32.32.21.91.4
Body weight0.83.74.5-2.12.1-2.11.8-1.81.8-1.82.02.01.91.81.5
Weight adjusted by age0.20.30.7-0.80.8-0.80.4-0.40.4-0.40.50.50.40.2-0.1
Bone surface0.30.63.20.8-0.70.70.3-0.30.3-0.30.40.40.31.11.8
Bone volume0.30.63.60.6-0.50.50.3-0.30.3-0.30.60.60.31.21.9
Breakpoint value in progressive ratio session3.94.75.02.1-2.12.1-2.22.2-2.22.2-2.2-2.2-2.1-2.1-2.0
Number of licking bursts0.10.10.6-0.40.3-0.3-0.20.2-0.20.2-0.1-0.1-0.2-0.5-0.8
Context. condit. distance diff. score0.20.30.4-0.60.6-0.60.6-0.60.6-0.60.10.10.60.40.3
Locomotion velocity, session 10.20.30.80.9-0.80.8-0.40.4-0.40.4-0.3-0.3-0.4-0.00.3
Locomotion distance, session 10.30.31.60.8-0.70.70.1-0.10.1-0.1-0.3-0.30.10.71.3
Locomotion velocity, session 22.93.46.42.5-2.52.5-1.51.5-1.51.5-2.1-2.1-1.5-1.0-0.4
Locomotion distance, session 21.01.43.51.9-1.81.8-1.01.0-1.01.0-1.0-1.0-1.0-0.20.4
Locomotion velocity, session 36.67.69.82.8-2.82.8-2.62.6-2.62.6-3.1-3.1-2.6-2.7-2.4
Locomotion distance, session 30.00.00.1-0.10.0-0.0-0.00.0-0.00.0-0.2-0.2-0.0-0.2-0.3
Stereotopy head waving bouts, day 34.65.47.32.7-2.72.7-2.22.2-2.22.2-2.6-2.6-2.2-1.9-1.5
Stereotopy head waving duration, day 35.97.08.62.9-2.92.9-2.52.5-2.52.5-2.9-2.9-2.5-2.4-2.0
Locomotion velocity, session 70.60.71.60.6-0.60.6-0.80.8-0.80.8-1.2-1.2-0.8-0.7-0.7
Locomotion distance, session 70.10.10.4-0.70.6-0.60.1-0.10.1-0.1-0.0-0.00.1-0.1-0.4
Stereotopy head waving bouts, day 70.10.20.60.2-0.10.10.4-0.40.4-0.40.20.20.40.60.8
Stereotopy head waving duration, day 70.20.20.60.8-0.70.7-0.20.2-0.20.2-0.3-0.3-0.20.10.5
Locomotion velocity, session 80.40.51.21.1-1.01.0-0.30.3-0.30.3-1.0-1.0-0.30.10.6
Locomotion distance, session 80.10.20.50.7-0.60.6-0.20.2-0.20.2-0.7-0.7-0.2-0.00.2
Degree of sensitization distance0.40.40.5-0.70.7-0.70.7-0.70.7-0.70.50.50.70.70.6
Degree of sensitization stereotypy2.12.32.6-1.31.3-1.31.6-1.61.6-1.61.61.61.61.61.6
Conditioned locomotion0.81.02.0-1.41.4-1.40.9-0.90.9-0.90.90.90.90.50.1
Cocaine response after cond. corrected3.94.78.1-2.82.8-2.82.1-2.12.1-2.12.02.02.11.40.8
Cocaine response after cond. not corrected4.14.98.4-2.92.8-2.82.2-2.22.2-2.22.02.02.21.40.8
Cocaine response before conditioning0.40.50.70.8-0.80.8-0.70.7-0.70.7-0.7-0.7-0.7-0.6-0.4
Saline control response0.10.10.2-0.50.5-0.50.2-0.20.2-0.20.40.40.20.1-0.1
Bone: connectivity density0.60.92.5-0.40.4-0.41.0-1.01.0-1.00.90.91.01.31.6
Bone: cortical apparent density1.01.31.8-1.21.2-1.21.1-1.11.1-1.11.41.41.11.11.0
Bone: cortical area0.71.01.8-0.70.7-0.71.0-1.01.0-1.01.11.11.01.21.4
Bone: cortical porosity0.10.10.20.4-0.40.4-0.20.2-0.20.2-0.2-0.2-0.20.10.3
Bone: cortical porosity0.10.10.80.2-0.20.20.2-0.20.2-0.20.20.20.20.60.9
Bone: cortical thickness1.32.22.7-1.31.3-1.31.5-1.51.5-1.51.61.61.51.61.6
Bone: cortical thickness0.10.20.8-0.10.1-0.1-0.40.4-0.40.4-0.2-0.2-0.4-0.6-0.9
Bone: cortical tissue density0.70.91.3-0.91.0-1.00.9-0.90.9-0.91.21.20.90.90.8
Condit. Reinf. active minus inactive responses4.34.85.72.4-2.42.4-2.12.1-2.12.1-2.3-2.3-2.1-2.1-1.9
Condit. Reinf. active-inactive response ratio2.52.63.41.5-1.51.5-1.61.6-1.61.6-1.5-1.5-1.6-1.8-1.8
Condit. Reinf. active responses3.13.96.02.5-2.42.4-1.91.9-1.91.9-2.0-2.0-1.9-1.5-1.1
Condit. Reinf. inactive responses0.50.61.51.2-1.21.2-0.60.6-0.60.6-0.7-0.7-0.6-0.10.4
Incentive salience index mean1.92.43.82.0-1.91.9-1.41.4-1.41.4-1.6-1.6-1.4-1.2-0.8
Condit. Reinf. lever presses0.20.31.60.5-0.40.40.3-0.30.3-0.30.30.30.30.81.3
Condit. Reinf. active minus inactive responses2.43.24.21.5-1.51.5-1.91.9-1.91.9-1.5-1.5-1.9-2.0-2.1
Condit. Reinf. active-inactive response ratio0.30.31.1-0.0-0.00.0-0.60.6-0.60.6-0.0-0.0-0.6-0.8-1.1
Condit. Reinf. active responses2.23.03.61.6-1.61.6-1.91.9-1.91.9-1.5-1.5-1.9-1.8-1.8
Condit. Reinf. inactive responses1.01.41.71.1-1.11.1-1.21.2-1.21.2-1.3-1.3-1.2-1.1-1.0
Condit. Reinf. lever presses2.02.83.31.5-1.51.5-1.81.8-1.81.8-1.5-1.5-1.8-1.8-1.8
Condit. Reinf. lever reinforcers received1.72.43.31.2-1.31.3-1.71.7-1.71.7-1.3-1.3-1.7-1.8-1.8
Conditioned reinforcement - actives1.22.02.61.0-1.11.1-1.61.6-1.61.6-1.4-1.4-1.5-1.5-1.6
Conditioned reinforcement - inactives0.00.00.1-0.20.2-0.2-0.10.1-0.10.1-0.0-0.00.1-0.2-0.3
Conditioned locomotion7.29.410.73.1-3.13.1-3.33.3-3.33.3-2.9-2.9-3.1-2.7-2.4
Patch foraging indifference point 0 sec0.20.40.5-0.50.5-0.50.5-0.50.5-0.50.70.70.50.70.7
Patch foraging indifference point AUC0.81.21.51.0-1.01.0-1.21.2-1.21.2-0.9-0.9-1.2-1.1-1.1
Delay disc. indifference point, 0s delay9.310.213.2-2.72.8-2.83.2-3.23.2-3.23.33.33.33.63.6
Delay disc. indifference point, 16s delay0.20.20.3-0.40.4-0.40.6-0.60.6-0.60.40.40.50.40.4
Delay disc. indifference point, 2s delay6.87.58.0-2.62.6-2.62.8-2.82.8-2.82.72.72.82.82.7
Delay disc. indifference point, 24s delay0.60.70.9-1.01.0-1.00.8-0.80.8-0.80.90.90.70.60.4
Delay disc. indifference point, 4s delay1.61.62.2-1.11.1-1.11.5-1.51.5-1.51.11.11.41.21.2
Delay disc. indifference point, 8s delay1.01.21.9-1.41.4-1.41.1-1.11.1-1.10.90.91.10.80.6
Indifference point function ln k0.10.20.3-0.50.5-0.50.4-0.40.4-0.40.30.30.40.20.1
Indifference point function log k0.10.20.3-0.50.5-0.50.4-0.40.4-0.40.30.30.40.20.1
Patch foraging total patch changes 0 sec0.10.20.4-0.40.4-0.50.4-0.40.4-0.40.60.60.50.60.6
Patch foraging total patch changes 12 sec0.20.30.6-0.80.8-0.80.5-0.50.5-0.50.60.60.50.40.2
Patch foraging total patch changes 18 sec0.71.11.31.1-1.11.1-1.11.1-1.11.1-0.9-0.9-1.1-0.9-0.7
Patch foraging total patch changes 24 sec0.00.10.10.3-0.30.3-0.40.4-0.40.4-0.0-0.0-0.3-0.1-0.0
Patch foraging total patch changes 6 sec0.10.20.30.5-0.50.5-0.50.5-0.50.5-0.3-0.3-0.5-0.2-0.1
Patch foraging time to switch 0 sec1.22.65.4-0.91.0-1.01.7-1.71.7-1.71.31.31.72.12.3
Patch foraging water rate 0 sec0.20.41.8-0.40.3-0.3-0.40.4-0.40.4-0.5-0.5-0.5-0.9-1.4
Patch foraging water rate 12 sec0.51.02.5-1.61.5-1.50.8-0.80.8-0.81.01.00.80.2-0.3
Patch foraging water rate 18 sec0.71.15.0-0.30.2-0.2-0.90.9-0.90.9-0.9-0.9-0.9-1.6-2.2
Patch foraging water rate 24 sec0.30.51.9-1.11.0-1.00.1-0.10.1-0.10.00.00.0-0.7-1.4
Patch foraging water rate 6 sec0.71.03.30.2-0.30.3-1.01.0-1.01.0-0.7-0.7-1.1-1.5-1.8
Seeking ratio, delayed vs. immediate footshock3.54.35.42.3-2.32.3-2.12.1-2.12.1-2.1-2.1-2.1-1.8-1.5
Distance traveled before self-admin0.20.30.5-0.40.4-0.40.4-0.40.4-0.40.60.60.60.60.7
Distance traveled after self-admin0.00.00.00.1-0.10.1-0.20.2-0.20.20.00.0-0.10.00.1
Extensor digitorum longus weight3.814.919.9-4.54.4-4.43.9-3.93.9-3.93.73.73.93.22.4
Bone: elastic displacement0.10.10.20.4-0.40.4-0.40.4-0.40.4-0.2-0.2-0.4-0.3-0.3
Bone: elastic work0.40.50.5-0.70.7-0.70.7-0.70.7-0.70.70.70.70.70.6
Bone: endosteal estimation0.20.40.5-0.50.6-0.60.7-0.70.7-0.70.50.50.70.60.6
Bone: endosteal perimeter0.20.40.70.8-0.80.8-0.50.5-0.50.5-0.6-0.6-0.5-0.4-0.1
Epididymis fat weight0.00.10.8-0.20.1-0.1-0.10.1-0.10.1-0.4-0.4-0.1-0.6-0.9
Delta time in closed arm before/after self-admin0.40.41.2-1.11.0-1.00.1-0.10.1-0.10.40.40.2-0.3-0.9
Delta time in open arm before/after self-admin0.70.60.8-0.70.8-0.80.9-0.90.9-0.90.70.70.90.70.7
Diff in mean of infusions in LGA sessions1.51.92.41.5-1.51.5-1.21.2-1.21.2-1.6-1.6-1.2-1.3-1.1
Delay discount exponential model param1.82.02.31.5-1.51.5-1.51.5-1.51.5-1.3-1.3-1.5-1.3-1.1
Extinction: sum of active levers before priming1.21.31.80.9-0.90.9-1.31.3-1.31.3-1.1-1.1-1.1-1.2-1.2
Active lever presses in extinction session 62.02.02.61.6-1.51.5-1.61.6-1.61.6-1.2-1.2-1.5-1.1-0.8
Bone: final force1.62.63.1-1.41.5-1.51.6-1.61.6-1.61.61.61.61.81.8
Bone: final moment1.32.12.6-1.31.3-1.31.5-1.51.5-1.51.51.51.51.61.6
Food consumed during 24 hour testing period0.40.60.9-1.01.0-1.00.8-0.80.8-0.80.60.60.80.60.4
Glucose2.64.15.1-2.22.2-2.22.0-2.02.0-2.02.12.12.01.81.5
Heart weight0.81.32.70.7-0.80.8-1.11.1-1.11.1-1.1-1.1-1.1-1.5-1.6
Delay discount hyperbolic model param3.33.64.02.0-2.02.0-2.02.0-2.02.0-1.8-1.8-2.0-1.8-1.6
Intermittent access intake day 1-15 change3.77.58.52.5-2.52.5-2.92.9-2.92.9-2.7-2.7-2.9-2.8-2.7
Intermittent access intake escalation3.26.67.42.3-2.42.4-2.72.7-2.72.7-2.5-2.5-2.7-2.6-2.5
Intermittent access intake escalation 25.05.76.52.2-2.22.3-2.52.5-2.52.5-2.3-2.3-2.5-2.4-2.3
Intermitt. access day 1 inactive lever presses0.10.51.50.0-0.10.1-0.80.8-0.80.8-0.6-0.6-0.6-1.0-1.2
Intermitt. access day 15 inactive lever presses0.20.40.60.7-0.70.7-0.60.6-0.60.6-0.7-0.7-0.6-0.5-0.4
Intermitt. access escalation Index0.91.32.2-0.80.8-0.81.2-1.21.2-1.21.21.21.11.41.5
Intermittent access day 1 total infusions0.20.30.70.2-0.30.3-0.60.6-0.60.6-0.6-0.6-0.4-0.7-0.9
Intermittent access day 15 total infusions2.94.35.11.8-1.81.9-2.22.2-2.22.2-2.0-2.0-2.0-2.1-2.0
Intermittent access terminal intake (last 3 days)2.12.83.41.5-1.51.5-1.91.9-1.91.9-1.7-1.7-1.6-1.6-1.5
Intermittent access total infusions1.21.41.81.0-1.01.0-1.41.4-1.41.4-1.2-1.2-1.1-1.2-1.2
Intermittent access day 1 locomotion2.02.53.61.2-1.21.2-1.71.7-1.71.7-1.7-1.7-1.4-1.8-1.9
Intermittent access day 15 total locomotion3.46.37.02.2-2.32.3-2.62.6-2.62.6-2.5-2.5-2.4-2.6-2.5
Intermittent access total locomotion2.93.44.01.6-1.61.6-2.02.0-2.02.0-1.9-1.9-1.8-1.9-1.9
Intermittent access standard deviation3.77.78.52.8-2.82.8-2.92.9-2.92.9-2.8-2.8-2.8-2.6-2.4
Left kidney weight0.00.10.6-0.30.2-0.2-0.30.3-0.30.3-0.4-0.4-0.2-0.5-0.8
Right kidney weight0.62.74.31.1-1.21.2-1.71.7-1.71.7-1.7-1.7-1.6-1.9-2.1
Cocaine induced anxiety0.71.02.21.5-1.41.4-0.90.9-0.90.9-0.9-0.9-1.0-0.5-0.0
Post-drug Anxiety0.80.92.11.5-1.41.4-0.70.7-0.70.7-0.9-0.9-0.7-0.40.1
Baseline Anxiety0.10.10.20.2-0.20.2-0.30.3-0.30.3-0.3-0.3-0.1-0.4-0.4
Tail length3.614.016.03.6-3.73.7-3.83.8-3.83.8-4.0-4.0-3.8-3.6-3.3
Length with tail2.08.910.52.9-2.92.9-3.03.0-3.03.0-3.2-3.2-3.0-2.8-2.6
Length without tail0.00.00.0-0.20.2-0.20.1-0.10.1-0.10.10.10.10.0-0.0
Times rat made contact with spout0.10.10.4-0.60.6-0.60.2-0.20.2-0.20.10.10.2-0.0-0.2
Lifetime Intake0.70.81.10.7-0.70.7-1.11.1-1.11.1-0.9-0.9-0.8-0.9-1.0
Liver weight, left0.91.51.8-1.31.3-1.31.2-1.21.2-1.21.31.31.30.90.7
Liver weight, right0.40.81.4-1.21.2-1.20.8-0.80.8-0.80.70.70.90.60.3
Locomotor activity2.43.75.52.3-2.32.3-2.02.0-2.02.0-1.7-1.7-2.0-1.2-0.7
Locomotor testing distance1.22.23.51.9-1.81.8-1.61.6-1.61.6-1.2-1.2-1.6-1.0-0.5
Locomotor testing rearing0.00.10.30.0-0.00.0-0.30.3-0.30.30.00.0-0.3-0.5-0.6
Locomotion in novel chamber1.11.41.81.0-1.01.0-1.31.3-1.31.3-1.0-1.0-1.3-1.2-1.2
Locomotion in novel chamber post-restriction1.32.12.61.3-1.31.3-1.51.5-1.51.5-1.6-1.6-1.4-1.5-1.5
Fecal boli incidents, locomotor time 11.11.62.0-1.41.4-1.41.2-1.21.2-1.21.11.11.31.31.1
Change in fecal boli incidents, locomotor task0.10.10.20.4-0.40.4-0.50.5-0.50.5-0.3-0.3-0.4-0.2-0.0
Time >=10cm from walls, locomotor time 10.70.81.9-0.60.6-0.60.7-0.70.7-0.71.11.10.61.21.4
Bouts of movement, locomotor time 10.40.50.80.6-0.60.6-0.70.7-0.70.7-0.9-0.9-0.7-0.7-0.7
Total resting periods, locomotor time 10.50.60.90.7-0.70.7-0.70.7-0.70.7-0.9-0.9-0.7-0.7-0.7
Rest time, locomotor task time 10.30.30.80.7-0.60.6-0.50.5-0.50.5-0.9-0.9-0.4-0.3-0.2
Distance moved, locomotor task time 10.91.32.3-0.80.9-0.91.1-1.11.1-1.11.41.41.01.41.5
Vertical activity count, locomotor time 10.10.30.6-0.70.7-0.70.3-0.30.3-0.30.80.80.30.20.0
Time >=10cm from walls, locomotor time 20.81.22.1-1.41.4-1.40.9-0.90.9-0.91.21.20.91.00.7
Bouts of movement, locomotor time 20.10.20.70.8-0.80.8-0.30.3-0.30.3-0.4-0.4-0.3-0.10.2
Total resting periods, locomotor time 20.10.20.60.8-0.70.7-0.20.2-0.20.2-0.4-0.4-0.30.00.3
Rest time, locomotor task time 20.40.51.01.0-1.01.0-0.60.6-0.60.6-0.8-0.8-0.7-0.5-0.2
Distance moved, locomotor task time 20.50.60.9-0.90.9-0.90.7-0.70.7-0.70.80.80.70.60.4
Vertical activity count, locomotor time 20.30.41.0-1.00.9-0.90.5-0.50.5-0.50.40.40.50.2-0.1
Light reinforcement 13.89.412.93.6-3.63.5-3.13.1-3.13.1-2.9-2.9-3.1-2.5-1.9
Light reinforcement 21.52.33.41.9-1.81.8-1.51.5-1.51.5-1.5-1.5-1.5-1.2-0.9
Bone: marrow area0.20.40.5-0.50.6-0.60.7-0.70.7-0.70.50.50.70.60.6
Bone: maximum diameter0.61.12.01.4-1.41.4-1.01.0-1.01.0-1.0-1.0-1.0-0.6-0.3
Bone: maximum force1.42.62.7-1.51.5-1.51.6-1.61.6-1.61.61.61.61.61.5
Bone: maximum moment1.22.22.3-1.41.4-1.41.5-1.51.5-1.51.51.51.51.51.4
Mean time between licks in bursts2.56.26.72.5-2.52.5-2.62.6-2.62.6-2.3-2.3-2.6-2.4-2.2
Mean num. licks in bursts0.00.10.2-0.10.1-0.10.3-0.30.3-0.30.10.10.30.30.4
Cd content in liver0.10.10.20.5-0.50.5-0.40.4-0.40.4-0.2-0.2-0.4-0.2-0.1
Co content in liver1.72.02.31.3-1.31.3-1.51.5-1.51.5-1.2-1.2-1.5-1.4-1.4
Cu content in liver0.10.10.40.6-0.60.6-0.20.2-0.20.2-0.3-0.3-0.20.20.4
Fe content in liver0.20.30.60.4-0.40.4-0.50.5-0.50.5-0.8-0.8-0.5-0.5-0.6
K content in liver0.10.10.40.3-0.20.20.1-0.10.1-0.10.20.20.10.40.6
Mg content in liver0.20.20.40.6-0.60.6-0.50.5-0.50.5-0.3-0.3-0.5-0.2-0.1
Mn content in liver0.91.02.31.5-1.41.4-0.80.8-0.80.8-1.1-1.1-0.8-0.30.2
Na content in liver1.21.32.7-0.70.8-0.81.2-1.21.2-1.21.11.11.21.51.6
Rb content in liver0.10.10.70.3-0.20.20.2-0.20.2-0.20.20.20.20.60.8
Se content in liver0.30.40.80.6-0.60.6-0.50.5-0.50.5-0.9-0.9-0.5-0.5-0.4
Sr content in liver0.00.00.1-0.20.1-0.1-0.00.0-0.00.0-0.0-0.0-0.0-0.1-0.3
Zn content in liver4.85.48.01.8-1.91.9-2.42.4-2.42.4-2.1-2.1-2.4-2.7-2.8
Bone: minimum diameter0.00.10.2-0.10.1-0.10.3-0.30.3-0.30.10.10.30.40.5
Time in familiar zone, hab. session 12.72.63.71.4-1.51.5-1.51.5-1.51.5-1.9-1.9-1.5-1.7-1.7
Time in novel zone, hab. session 11.61.62.3-1.01.0-1.01.2-1.21.2-1.21.51.51.21.51.5
Total zone transitions, hab. session 10.50.71.91.4-1.31.3-0.70.7-0.70.7-0.8-0.8-0.7-0.10.3
Total locomotion distance, hab. session 10.71.02.51.6-1.51.5-0.70.7-0.70.7-1.0-1.0-0.70.00.6
Locomotion velocity, hab. session 11.11.53.41.9-1.81.8-1.01.0-1.01.0-1.3-1.3-1.0-0.30.3
Time in familiar zone, hab. session 27.47.89.02.6-2.62.6-2.82.8-2.82.8-2.9-2.9-2.8-3.0-2.9
Time in novel zone, hab. session 25.75.86.7-2.22.2-2.22.4-2.42.4-2.42.52.52.42.62.5
Total zone transitions, hab. session 20.81.04.20.00.1-0.10.9-0.90.9-0.91.01.00.91.62.0
Total locomotion distance, hab. session 20.70.92.41.5-1.51.5-0.70.7-0.70.7-0.7-0.7-0.7-0.20.3
Locomotion velocity, hab. session 20.60.82.51.6-1.51.5-0.60.6-0.60.6-0.6-0.6-0.60.00.6
Novel to familiar place preference ratio5.05.57.1-2.02.1-2.12.4-2.42.4-2.42.42.42.42.62.7
Novelty place preference3.23.44.8-1.51.6-1.61.9-1.91.9-1.91.81.81.92.12.2
Time in novel zone, NPP test3.53.84.9-1.71.7-1.72.0-2.02.0-2.01.91.92.02.22.2
Total zone transitions, NPP test0.20.31.60.3-0.20.20.4-0.40.4-0.40.40.40.40.91.3
Total locomotion distance, NPP test0.20.31.50.3-0.20.20.5-0.50.5-0.50.30.30.50.91.2
Locomotion velocity, NPP test0.10.21.00.5-0.50.50.2-0.20.2-0.20.10.10.20.61.0
Intraocular pressure0.20.31.5-0.30.2-0.2-0.40.4-0.40.4-0.3-0.3-0.4-0.9-1.2
Delta distance traveled before/after self-admin0.50.50.80.7-0.70.7-0.70.7-0.70.7-0.8-0.8-0.9-0.7-0.7
Delta ambulatory time before/after self-admin0.40.40.70.7-0.70.7-0.60.6-0.60.6-0.8-0.8-0.8-0.6-0.5
Parametrial fat weight0.00.00.10.1-0.10.10.1-0.10.1-0.10.10.10.10.20.4
Pavlov. Cond. lever latency0.20.21.0-0.30.3-0.3-0.30.3-0.30.30.10.1-0.3-0.7-1.0
Pavlov. Cond. magazine entry latency3.34.35.52.2-2.22.2-2.02.0-2.02.0-2.3-2.3-2.0-1.9-1.6
Pavlov. Cond. change in total contacts0.10.10.30.4-0.30.3-0.20.2-0.20.2-0.5-0.5-0.2-0.10.0
Pavlov. Cond. index score0.40.51.11.0-1.01.0-0.50.5-0.50.5-1.1-1.1-0.5-0.3-0.1
Pavlov. Cond. latency score0.40.51.01.0-1.01.0-0.40.4-0.40.4-1.0-1.0-0.4-0.10.2
Pavlov. Cond. lever contacts0.10.20.90.3-0.20.20.3-0.30.3-0.3-0.1-0.10.30.60.9
Pavlov. Cond. magazine entry number1.01.21.8-1.21.2-1.21.0-1.01.0-1.01.31.31.01.00.9
Pavlov. Cond. intertrial magazine entries0.20.30.90.2-0.20.2-0.60.6-0.60.6-0.4-0.4-0.6-0.8-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.31.1-1.11.1-0.60.6-0.60.6-1.2-1.2-0.6-0.5-0.2
Pavlov. Cond. response bias0.91.21.91.2-1.21.2-1.01.0-1.01.0-1.4-1.4-1.0-0.9-0.8
Pavlov. Cond. lever latency0.70.91.2-0.80.9-0.91.1-1.11.1-1.10.80.81.11.01.0
Pavlov. Cond. magazine entry latency0.40.50.60.7-0.70.7-0.70.7-0.70.7-0.8-0.8-0.7-0.7-0.6
Pavlov. Cond. change in total contacts0.50.81.10.7-0.70.7-1.01.0-1.01.0-0.6-0.6-1.0-1.0-1.0
Pavlov. Cond. index score0.60.81.00.8-0.80.8-1.01.0-1.01.0-0.9-0.9-1.0-1.0-1.0
Pavlov. Cond. latency score0.60.81.00.8-0.80.8-1.01.0-1.01.0-0.8-0.8-1.0-0.9-0.8
Pavlov. Cond. lever contacts0.60.81.10.7-0.70.7-1.01.0-1.01.0-0.8-0.8-1.0-1.0-1.1
Pavlov. Cond. magazine entry number0.60.81.1-0.90.9-0.90.9-0.90.9-0.91.01.00.90.90.8
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.80.7-0.70.5-0.50.5-0.50.60.60.50.20.0
Pavlov. Cond. lever-magazine prob. diff.0.60.91.00.8-0.80.8-1.01.0-1.01.0-0.9-0.9-1.0-0.9-0.9
Pavlov. Cond. response bias1.72.32.71.2-1.31.3-1.61.6-1.61.6-1.4-1.4-1.6-1.6-1.7
Time in closed arm before self-admin0.60.71.7-0.40.5-0.50.9-0.90.9-0.90.70.70.81.11.3
Time in closed arm after self-admin0.30.30.60.3-0.30.3-0.50.5-0.50.5-0.5-0.5-0.6-0.7-0.8
Time in open arm before self-admin0.10.10.30.3-0.30.3-0.40.4-0.40.4-0.2-0.2-0.6-0.2-0.2
Time in open arm after self-admin1.01.11.2-1.11.1-1.11.1-1.11.1-1.11.11.11.01.00.8
Bone: periosteal estimation0.40.81.4-0.50.6-0.60.9-0.90.9-0.90.80.80.91.01.2
Bone: periosteal perimeter0.00.10.20.5-0.40.4-0.10.1-0.10.1-0.1-0.1-0.10.20.4
Bone: post-yield work0.50.81.1-1.01.0-1.01.0-1.01.0-1.00.70.71.00.70.6
Progressive ratio test 1 active lever presses0.30.31.10.1-0.10.1-0.60.6-0.60.6-0.6-0.6-0.3-0.8-1.0
Progressive ratio test 1 breakpoint0.20.31.00.0-0.10.1-0.50.5-0.50.5-0.6-0.6-0.3-0.8-1.0
Progressive ratio test 1 inactive lever presses0.40.50.80.5-0.60.6-0.70.7-0.70.7-0.8-0.8-0.6-0.8-0.9
Progressive ratio test 2 active lever presses0.60.71.60.2-0.20.3-0.90.9-0.90.9-0.7-0.7-0.7-1.0-1.3
Progressive ratio test 2 breakpoint0.70.81.80.3-0.30.3-1.01.0-1.01.0-0.8-0.8-0.7-1.1-1.3
Progressive ratio test 2 inactive lever presses0.10.20.40.3-0.40.4-0.60.6-0.60.6-0.4-0.4-0.4-0.4-0.4
Incentive Sensitization - Responses0.10.10.4-0.30.3-0.3-0.30.3-0.30.3-0.1-0.1-0.2-0.4-0.7
Incentive Sensitization - Breakpoint0.10.10.5-0.20.1-0.1-0.40.4-0.40.4-0.2-0.2-0.3-0.5-0.7
Sum of active levers in priming session hrs 5-60.00.00.0-0.10.1-0.10.1-0.10.1-0.10.20.20.00.20.1
Progressive ratio0.10.20.3-0.60.6-0.50.5-0.50.5-0.50.30.30.50.30.1
Food seeking constrained by brief footshock0.20.30.60.7-0.70.7-0.50.5-0.50.5-0.8-0.8-0.3-0.2-0.1
Seeking ratio, punishment vs. effort0.20.30.60.8-0.80.8-0.50.5-0.50.5-0.6-0.6-0.4-0.2-0.0
Retroperitoneal fat weight0.31.22.0-1.41.4-1.41.1-1.11.1-1.10.90.91.20.60.2
Reaction time number correct0.20.41.1-1.11.0-1.00.5-0.50.5-0.50.30.30.4-0.1-0.6
Reaction time mean minus median0.30.70.90.7-0.70.8-0.90.9-0.90.9-0.9-0.9-0.9-1.0-1.0
Reaction time mean minus median AUC0.00.10.30.0-0.00.00.3-0.30.3-0.30.00.00.30.40.6
Reaction time num false alarms0.10.10.5-0.70.6-0.60.2-0.20.2-0.20.20.20.2-0.1-0.4
Reaction time num false alarms AUC0.10.20.5-0.70.7-0.70.2-0.20.2-0.20.20.20.2-0.2-0.5
Reaction time trials correct on left0.20.41.1-1.11.0-1.00.5-0.50.5-0.50.30.30.4-0.1-0.6
Reaction time trials on left0.20.41.1-1.11.0-1.00.5-0.50.5-0.50.30.30.5-0.1-0.5
Reaction time mean0.10.10.2-0.20.2-0.20.3-0.30.3-0.30.30.30.30.40.5
Reaction time mean AUC0.10.10.3-0.20.3-0.30.3-0.30.3-0.30.50.50.30.50.5
Median of all reaction times0.40.50.9-0.60.6-0.60.7-0.70.7-0.70.80.80.70.90.9
Reaction time omissions0.10.10.20.5-0.50.5-0.20.2-0.20.2-0.1-0.1-0.20.00.2
Reaction time false alarm rate0.00.00.1-0.30.3-0.30.2-0.20.2-0.20.20.20.20.20.1
Reaction time premature initiation rate1.11.52.01.0-1.11.1-1.31.3-1.31.3-1.1-1.1-1.3-1.4-1.4
Reaction time premature initiations0.81.43.40.6-0.60.7-1.21.2-1.21.2-1.1-1.1-1.2-1.6-1.8
Std. dev. reaction times0.10.10.10.3-0.30.3-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.3
Reaction time trials completed0.20.41.1-1.11.0-1.00.5-0.50.5-0.50.30.30.5-0.1-0.5
Reaction time trials AUC0.20.41.1-1.11.0-1.00.4-0.40.4-0.40.30.30.4-0.2-0.7
Run reversals in cocaine runway, females0.50.50.80.9-0.90.9-0.60.6-0.60.6-0.8-0.8-0.5-0.4-0.2
Run reversals in cocaine runway, males1.61.62.31.5-1.51.5-1.21.2-1.21.2-1.3-1.3-1.1-1.0-0.7
Latency to leave start box in cocaine runway0.20.20.60.7-0.70.7-0.50.5-0.50.50.10.1-0.40.00.3
Latency to leave start box in cocaine runway, F0.40.51.90.00.1-0.10.2-0.20.2-0.21.11.10.51.01.4
Latency to leave start box in cocaine runway, M2.01.92.31.3-1.31.3-1.31.3-1.31.3-1.4-1.4-1.5-1.5-1.5
Std. dev. time between licks in bursts0.50.60.90.9-0.90.9-0.80.8-0.80.8-0.7-0.7-0.8-0.6-0.5
Total sessions with >9 infusions0.40.50.80.4-0.40.4-0.90.9-0.90.9-0.7-0.7-0.6-0.8-0.9
Short access day 1 total inactive lever presses0.40.50.70.6-0.60.6-0.80.8-0.80.8-0.8-0.8-0.7-0.7-0.7
Short access day 10 total inactive lever presses0.00.00.1-0.20.2-0.2-0.20.2-0.20.2-0.0-0.0-0.3-0.2-0.4
Short access day 1 total infusions0.40.50.60.7-0.70.7-0.80.8-0.80.8-0.8-0.8-0.6-0.7-0.6
Short access day 10 total infusions0.20.20.60.1-0.10.2-0.50.5-0.50.5-0.5-0.5-0.2-0.6-0.8
Short access total infusions0.40.50.80.5-0.50.5-0.90.9-0.90.9-0.7-0.7-0.5-0.7-0.8
Short access day 1 locomotion1.62.02.31.3-1.31.3-1.51.5-1.51.5-1.4-1.4-1.3-1.4-1.3
Short access day 10 total locomotion5.09.210.92.5-2.62.6-3.33.3-3.33.3-3.0-3.0-3.0-3.2-3.2
Short access total locomotion2.83.44.31.5-1.51.6-2.12.1-2.12.1-1.8-1.8-1.7-1.8-1.8
One hour access (0.3 mA shock)0.00.00.1-0.20.2-0.2-0.10.1-0.10.1-0.1-0.10.1-0.2-0.3
Compulsive drug intake1.61.93.4-1.01.0-1.01.3-1.31.3-1.31.51.51.41.71.9
One hour access (shock baseline)0.71.02.10.6-0.70.7-1.01.0-1.01.0-1.1-1.1-0.8-1.3-1.4
Social response proportion0.60.71.31.1-1.11.1-0.80.8-0.80.8-0.7-0.7-0.8-0.5-0.3
Social responses6.17.910.03.2-3.13.1-2.92.9-2.92.9-2.6-2.6-2.9-2.4-1.9
Social time0.50.61.3-0.70.7-0.70.7-0.70.7-0.71.11.10.70.80.7
Soleus weight8.324.527.3-5.25.2-5.25.0-5.05.0-5.05.05.05.04.53.9
Bone: stiffness2.94.85.1-2.12.1-2.12.3-2.32.3-2.32.22.22.32.22.1
Tibialis anterior weight1.13.64.1-2.02.0-2.02.0-2.02.0-2.01.81.82.01.71.5
Time to tail flick, vehicle, before self-admin0.00.00.10.3-0.30.3-0.10.1-0.10.1-0.2-0.2-0.2-0.00.1
Time to tail flick, vehicle, after self-admin0.50.72.20.4-0.50.5-0.70.7-0.70.7-0.9-0.9-0.7-1.3-1.5
Time to tail flick, test, before self-admin0.20.20.40.7-0.60.6-0.30.3-0.30.3-0.3-0.3-0.5-0.10.1
Time to tail flick, test, after self-admin0.10.10.20.3-0.40.4-0.20.2-0.20.2-0.5-0.5-0.3-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.60.5-0.50.1-0.10.1-0.10.00.00.3-0.4-0.7
Delta time to tail flick, test, before/after SA0.10.10.6-0.10.1-0.1-0.20.2-0.20.2-0.4-0.4-0.2-0.6-0.8
Tibia length0.82.32.61.5-1.51.5-1.61.6-1.61.6-1.4-1.4-1.6-1.5-1.4
Ambulatory time before self-admin0.20.30.4-0.40.5-0.50.4-0.40.4-0.40.60.60.60.60.6
Ambulatory time after self-admin0.00.00.10.00.0-0.0-0.00.0-0.00.00.10.10.00.20.2
Bone: tissue strength2.22.22.8-1.41.4-1.41.5-1.51.5-1.51.71.71.51.51.5
Total heroin consumption1.41.62.21.5-1.51.5-1.31.3-1.31.3-1.2-1.2-1.3-1.0-0.8
Bone: trabecular number0.20.40.91.0-0.90.9-0.40.4-0.40.4-0.6-0.6-0.4-0.00.3
Bone: trabecular spacing0.30.31.0-1.00.9-0.90.1-0.10.1-0.10.20.20.1-0.5-1.0
Bone: trabecular thickness0.81.04.90.2-0.10.10.7-0.70.7-0.70.90.90.71.62.2
Bone: trabecular tissue density1.11.72.1-1.51.5-1.51.3-1.31.3-1.31.31.31.31.10.9
Water consumed over 24 hours0.81.01.3-1.01.0-1.01.1-1.11.1-1.10.90.91.11.11.1
Number of responses in last shaping day2.12.32.71.2-1.21.2-1.61.6-1.61.6-1.6-1.6-1.4-1.6-1.6