Hub : Genes

Ndufs7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_006240972.5 0.03 0.02 1.2e-03 0.01 0.02 0.02 0.02 1.0e-02 3.5e-03 6.4e-03 4.6e-03
2 LHb intron excision ratio chr7_10106899_10107529 0.13 0.09 3.9e-03 0.08 0.09 0.08 0.08 6.9e-03 4.7e-03 6.3e-03 7.5e-03
3 LHb intron excision ratio chr7_10106899_10107410 0.18 0.12 3.7e-04 0.11 0.12 0.1 0.1 1.7e-03 1.1e-03 1.8e-03 2.1e-03
4 Adipose alternative TSS NM_001008525.1 0.02 0.02 7.5e-03 0.01 0.01 0 0 3.7e-02 5.5e-02 1.4e-01 1.0e-01
5 Adipose alternative TSS XM_039079404.1 0.02 0.02 6.3e-03 0.02 0.01 0.01 0.01 3.5e-03 1.7e-02 5.3e-02 7.0e-03
6 Eye alternative TSS NM_001008525.1 0.36 0.22 5.5e-03 0.1 0.07 0.07 0.08 1.2e-02 3.2e-02 3.3e-02 2.4e-02
7 OFC intron excision ratio chr7_10106899_10107410 0.21 0.13 7.7e-05 0.17 0.14 0.16 0.15 9.2e-05 3.4e-04 1.5e-04 1.7e-04
8 OFC intron excision ratio chr7_10106899_10107529 0.2 0.13 1.5e-04 0.15 0.12 0.14 0.14 2.0e-04 7.6e-04 2.9e-04 4.1e-04
9 Adipose mRNA stability Ndufs7 0.02 0.02 5.6e-03 0 0 0 0 2.8e-01 1.7e-01 2.8e-01 1.7e-01
10 Eye intron excision ratio chr7_10106899_10107529 0.17 0.13 9.2e-03 0.03 -0 -0.01 -0 1.1e-01 3.6e-01 5.9e-01 3.5e-01
11 Adipose intron excision ratio chr7_10106899_10107529 0.03 0.03 7.4e-04 0.02 0.02 0.01 0.02 9.1e-04 1.5e-03 8.4e-03 2.9e-03
12 Eye isoform ratio NM_001008525.1 0.36 0.22 9.0e-03 0.11 0.13 0.07 0.11 8.4e-03 5.8e-03 3.5e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.62.90.00.1-0.1-0.70.7-0.70.7-0.70.7-0.8-0.71.7
Area under the delay curve1.72.62.8-1.61.6-1.6-1.71.7-1.71.7-1.71.7-1.5-1.71.3
BMI with tail5.920.724.3-4.94.9-4.9-4.54.5-4.54.5-4.54.5-4.7-4.63.4
BMI without tail1.05.17.1-2.72.6-2.6-2.22.2-2.22.2-2.22.2-2.3-2.21.4
Body weight0.83.64.5-2.12.1-2.1-1.81.8-1.81.8-1.81.8-2.0-1.91.5
Weight adjusted by age0.10.30.7-0.80.8-0.8-0.40.4-0.40.4-0.40.4-0.5-0.4-0.1
Bone surface0.20.53.20.8-0.70.7-0.30.3-0.30.3-0.30.3-0.4-0.31.8
Bone volume0.20.53.60.6-0.50.5-0.30.3-0.30.3-0.30.3-0.6-0.31.9
Breakpoint value in progressive ratio session2.64.75.02.1-2.12.12.2-2.22.2-2.22.2-2.22.22.1-2.0
Number of licking bursts0.00.10.6-0.40.3-0.30.2-0.20.2-0.20.2-0.20.10.2-0.8
Context. condit. distance diff. score0.30.30.4-0.60.6-0.6-0.60.6-0.60.6-0.60.6-0.1-0.60.3
Locomotion velocity, session 10.20.30.80.9-0.80.80.4-0.40.4-0.40.4-0.40.30.40.3
Locomotion distance, session 10.20.31.60.8-0.70.7-0.10.1-0.10.1-0.10.10.3-0.11.3
Locomotion velocity, session 22.83.36.42.5-2.52.51.5-1.51.5-1.51.5-1.52.11.5-0.4
Locomotion distance, session 21.11.53.51.9-1.81.81.0-1.01.0-1.01.0-1.01.01.00.4
Locomotion velocity, session 36.47.39.82.8-2.82.82.6-2.62.6-2.62.6-2.63.12.6-2.4
Locomotion distance, session 30.00.00.1-0.10.0-0.00.0-0.00.0-0.00.0-0.00.20.0-0.3
Stereotopy head waving bouts, day 34.55.37.32.7-2.72.72.2-2.22.2-2.22.2-2.22.62.2-1.5
Stereotopy head waving duration, day 35.66.98.62.9-2.92.92.5-2.52.5-2.52.5-2.52.92.5-2.0
Locomotion velocity, session 70.60.61.60.6-0.60.60.8-0.80.8-0.80.8-0.81.20.8-0.7
Locomotion distance, session 70.10.10.4-0.70.6-0.6-0.10.1-0.10.1-0.10.10.0-0.1-0.4
Stereotopy head waving bouts, day 70.10.20.60.2-0.10.1-0.40.4-0.40.4-0.40.4-0.2-0.40.8
Stereotopy head waving duration, day 70.10.20.60.8-0.70.70.2-0.20.2-0.20.2-0.20.30.20.5
Locomotion velocity, session 80.40.41.21.1-1.01.00.3-0.30.3-0.30.3-0.31.00.30.6
Locomotion distance, session 80.10.20.50.7-0.60.60.2-0.20.2-0.20.2-0.20.70.20.2
Degree of sensitization distance0.40.40.5-0.70.7-0.7-0.70.7-0.70.7-0.70.7-0.5-0.70.6
Degree of sensitization stereotypy2.12.32.6-1.31.3-1.3-1.61.6-1.61.6-1.61.6-1.6-1.61.6
Conditioned locomotion0.81.02.0-1.41.4-1.4-0.90.9-0.90.9-0.90.9-0.9-0.90.1
Cocaine response after cond. corrected3.35.08.1-2.82.8-2.8-2.12.1-2.12.1-2.12.1-2.0-2.10.8
Cocaine response after cond. not corrected3.55.18.4-2.92.8-2.8-2.22.2-2.22.2-2.22.2-2.0-2.20.8
Cocaine response before conditioning0.40.50.70.8-0.80.80.7-0.70.7-0.70.7-0.70.70.7-0.4
Saline control response0.10.10.2-0.50.5-0.5-0.20.2-0.20.2-0.20.2-0.4-0.2-0.1
Bone: connectivity density0.50.82.5-0.40.4-0.4-1.01.0-1.01.0-1.01.0-0.9-1.01.6
Bone: cortical apparent density0.81.31.8-1.21.2-1.2-1.11.1-1.11.1-1.11.1-1.4-1.11.0
Bone: cortical area0.61.01.8-0.70.7-0.7-1.01.0-1.01.0-1.01.0-1.1-1.01.4
Bone: cortical porosity0.10.10.20.4-0.40.40.2-0.20.2-0.20.2-0.20.20.20.3
Bone: cortical porosity0.10.10.80.2-0.20.2-0.20.2-0.20.2-0.20.2-0.2-0.20.9
Bone: cortical thickness1.32.12.7-1.31.3-1.3-1.51.5-1.51.5-1.51.5-1.6-1.51.6
Bone: cortical thickness0.10.20.8-0.10.1-0.10.4-0.40.4-0.40.4-0.40.20.4-0.9
Bone: cortical tissue density0.60.91.3-0.91.0-1.0-0.90.9-0.90.9-0.90.9-1.2-0.90.8
Condit. Reinf. active minus inactive responses4.24.75.72.4-2.42.42.1-2.12.1-2.12.1-2.12.32.1-1.9
Condit. Reinf. active-inactive response ratio2.42.63.41.5-1.51.51.6-1.61.6-1.61.6-1.61.51.6-1.8
Condit. Reinf. active responses3.13.96.02.5-2.42.41.9-1.91.9-1.91.9-1.92.01.9-1.1
Condit. Reinf. inactive responses0.50.61.51.2-1.21.20.6-0.60.6-0.60.6-0.60.70.60.4
Incentive salience index mean1.82.43.82.0-1.91.91.4-1.41.4-1.41.4-1.41.61.4-0.8
Condit. Reinf. lever presses0.20.21.60.5-0.40.4-0.30.3-0.30.3-0.30.3-0.3-0.31.3
Condit. Reinf. active minus inactive responses2.13.34.21.5-1.51.51.9-1.91.9-1.91.9-1.91.51.9-2.1
Condit. Reinf. active-inactive response ratio0.20.31.1-0.0-0.00.00.6-0.60.6-0.60.6-0.60.00.6-1.1
Condit. Reinf. active responses2.23.23.61.6-1.61.61.9-1.91.9-1.91.9-1.91.51.9-1.8
Condit. Reinf. inactive responses0.91.31.71.1-1.11.11.2-1.21.2-1.21.2-1.21.31.2-1.0
Condit. Reinf. lever presses2.02.83.31.5-1.51.51.8-1.81.8-1.81.8-1.81.51.8-1.8
Condit. Reinf. lever reinforcers received1.82.53.31.2-1.31.31.7-1.71.7-1.71.7-1.71.31.7-1.8
Conditioned reinforcement - actives0.52.12.61.0-1.11.11.6-1.61.6-1.61.6-1.61.41.5-1.6
Conditioned reinforcement - inactives0.00.00.1-0.20.2-0.20.1-0.10.1-0.10.1-0.10.0-0.1-0.3
Conditioned locomotion6.69.810.73.1-3.13.13.3-3.33.3-3.33.3-3.32.93.1-2.4
Patch foraging indifference point 0 sec0.10.30.5-0.50.5-0.5-0.50.5-0.50.5-0.50.5-0.7-0.50.7
Patch foraging indifference point AUC0.51.31.51.0-1.01.01.2-1.21.2-1.21.2-1.20.91.2-1.1
Delay disc. indifference point, 0s delay8.910.013.2-2.72.8-2.8-3.23.2-3.23.2-3.23.2-3.3-3.33.6
Delay disc. indifference point, 16s delay0.20.30.3-0.40.4-0.4-0.60.6-0.60.6-0.60.6-0.4-0.50.4
Delay disc. indifference point, 2s delay6.87.58.0-2.62.6-2.6-2.82.8-2.82.8-2.82.8-2.7-2.82.7
Delay disc. indifference point, 24s delay0.40.70.9-1.01.0-1.0-0.80.8-0.80.8-0.80.8-0.9-0.70.4
Delay disc. indifference point, 4s delay1.71.82.2-1.11.1-1.1-1.51.5-1.51.5-1.51.5-1.1-1.41.2
Delay disc. indifference point, 8s delay0.71.21.9-1.41.4-1.4-1.11.1-1.11.1-1.11.1-0.9-1.10.6
Indifference point function ln k0.10.20.3-0.50.5-0.5-0.40.4-0.40.4-0.40.4-0.3-0.40.1
Indifference point function log k0.10.20.3-0.50.5-0.5-0.40.4-0.40.4-0.40.4-0.3-0.40.1
Patch foraging total patch changes 0 sec0.10.20.4-0.40.4-0.5-0.40.4-0.40.4-0.40.4-0.6-0.50.6
Patch foraging total patch changes 12 sec0.20.30.6-0.80.8-0.8-0.50.5-0.50.5-0.50.5-0.6-0.50.2
Patch foraging total patch changes 18 sec0.51.11.31.1-1.11.11.1-1.11.1-1.11.1-1.10.91.1-0.7
Patch foraging total patch changes 24 sec0.00.10.10.3-0.30.30.4-0.40.4-0.40.4-0.40.00.3-0.0
Patch foraging total patch changes 6 sec0.10.20.30.5-0.50.50.5-0.50.5-0.50.5-0.50.30.5-0.1
Patch foraging time to switch 0 sec0.72.65.4-0.91.0-1.0-1.71.7-1.71.7-1.71.7-1.3-1.72.3
Patch foraging water rate 0 sec0.10.31.8-0.40.3-0.30.4-0.40.4-0.40.4-0.40.50.5-1.4
Patch foraging water rate 12 sec0.31.02.5-1.61.5-1.5-0.80.8-0.80.8-0.80.8-1.0-0.8-0.3
Patch foraging water rate 18 sec0.41.05.0-0.30.2-0.20.9-0.90.9-0.90.9-0.90.90.9-2.2
Patch foraging water rate 24 sec0.30.41.9-1.11.0-1.0-0.10.1-0.10.1-0.10.1-0.0-0.0-1.4
Patch foraging water rate 6 sec0.71.03.30.2-0.30.31.0-1.01.0-1.01.0-1.00.71.1-1.8
Seeking ratio, delayed vs. immediate footshock3.14.45.42.3-2.32.32.1-2.12.1-2.12.1-2.12.12.1-1.5
Distance traveled before self-admin0.10.20.5-0.40.4-0.4-0.40.4-0.40.4-0.40.4-0.6-0.60.7
Distance traveled after self-admin0.00.00.00.1-0.10.10.2-0.20.2-0.20.2-0.2-0.00.10.1
Extensor digitorum longus weight3.915.419.9-4.54.4-4.4-3.93.9-3.93.9-3.93.9-3.7-3.92.4
Bone: elastic displacement0.10.20.20.4-0.40.40.4-0.40.4-0.40.4-0.40.20.4-0.3
Bone: elastic work0.40.50.5-0.70.7-0.7-0.70.7-0.70.7-0.70.7-0.7-0.70.6
Bone: endosteal estimation0.20.50.5-0.50.6-0.6-0.70.7-0.70.7-0.70.7-0.5-0.70.6
Bone: endosteal perimeter0.20.40.70.8-0.80.80.5-0.50.5-0.50.5-0.50.60.5-0.1
Epididymis fat weight0.00.10.8-0.20.1-0.10.1-0.10.1-0.10.1-0.10.40.1-0.9
Delta time in closed arm before/after self-admin0.40.41.2-1.11.0-1.0-0.10.1-0.10.1-0.10.1-0.4-0.2-0.9
Delta time in open arm before/after self-admin0.60.70.8-0.70.8-0.8-0.90.9-0.90.9-0.90.9-0.7-0.90.7
Diff in mean of infusions in LGA sessions1.01.82.41.5-1.51.51.2-1.21.2-1.21.2-1.21.61.2-1.1
Delay discount exponential model param1.62.22.31.5-1.51.51.5-1.51.5-1.51.5-1.51.31.5-1.1
Extinction: sum of active levers before priming0.91.41.80.9-0.90.91.3-1.31.3-1.31.3-1.31.11.1-1.2
Active lever presses in extinction session 62.22.22.61.6-1.51.51.6-1.61.6-1.61.6-1.61.21.5-0.8
Bone: final force1.62.63.1-1.41.5-1.5-1.61.6-1.61.6-1.61.6-1.6-1.61.8
Bone: final moment1.32.12.6-1.31.3-1.3-1.51.5-1.51.5-1.51.5-1.5-1.51.6
Food consumed during 24 hour testing period0.30.60.9-1.01.0-1.0-0.80.8-0.80.8-0.80.8-0.6-0.80.4
Glucose2.64.15.1-2.22.2-2.2-2.02.0-2.02.0-2.02.0-2.1-2.01.5
Heart weight0.71.22.70.7-0.80.81.1-1.11.1-1.11.1-1.11.11.1-1.6
Delay discount hyperbolic model param2.93.74.02.0-2.02.02.0-2.02.0-2.02.0-2.01.82.0-1.6
Intermittent access intake day 1-15 change1.47.78.52.5-2.52.52.9-2.92.9-2.92.9-2.92.72.9-2.7
Intermittent access intake escalation1.26.87.42.3-2.42.42.7-2.72.7-2.72.7-2.72.52.7-2.5
Intermittent access intake escalation 23.45.86.52.2-2.22.32.5-2.52.5-2.52.5-2.52.32.5-2.3
Intermitt. access day 1 inactive lever presses0.00.51.50.0-0.10.10.8-0.80.8-0.80.8-0.80.60.6-1.2
Intermitt. access day 15 inactive lever presses0.10.40.60.7-0.70.70.6-0.60.6-0.60.6-0.60.70.6-0.4
Intermitt. access escalation Index0.41.22.2-0.80.8-0.8-1.21.2-1.21.2-1.21.2-1.2-1.11.5
Intermittent access day 1 total infusions0.10.30.70.2-0.30.30.6-0.60.6-0.60.6-0.60.60.4-0.9
Intermittent access day 15 total infusions1.84.45.11.8-1.81.92.2-2.22.2-2.22.2-2.22.02.0-2.0
Intermittent access terminal intake (last 3 days)1.72.93.41.5-1.51.51.9-1.91.9-1.91.9-1.91.71.6-1.5
Intermittent access total infusions1.31.51.81.0-1.01.01.4-1.41.4-1.41.4-1.41.21.1-1.2
Intermittent access day 1 locomotion1.32.53.61.2-1.21.21.7-1.71.7-1.71.7-1.71.71.4-1.9
Intermittent access day 15 total locomotion1.66.37.02.2-2.32.32.6-2.62.6-2.62.6-2.62.52.4-2.5
Intermittent access total locomotion2.93.54.01.6-1.61.62.0-2.02.0-2.02.0-2.01.91.8-1.9
Intermittent access standard deviation1.57.98.52.8-2.82.82.9-2.92.9-2.92.9-2.92.82.8-2.4
Left kidney weight0.00.10.6-0.30.2-0.20.3-0.30.3-0.30.3-0.30.40.2-0.8
Right kidney weight0.42.64.31.1-1.21.21.7-1.71.7-1.71.7-1.71.71.6-2.1
Cocaine induced anxiety0.41.12.21.5-1.41.40.9-0.90.9-0.90.9-0.90.91.0-0.0
Post-drug Anxiety0.80.92.11.5-1.41.40.7-0.70.7-0.70.7-0.70.90.70.1
Baseline Anxiety0.00.10.20.2-0.20.20.3-0.30.3-0.30.3-0.30.30.1-0.4
Tail length2.613.916.03.6-3.73.73.8-3.83.8-3.83.8-3.84.03.8-3.3
Length with tail2.08.910.52.9-2.92.93.0-3.03.0-3.03.0-3.03.23.0-2.6
Length without tail0.00.00.0-0.20.2-0.2-0.10.1-0.10.1-0.10.1-0.1-0.1-0.0
Times rat made contact with spout0.10.10.4-0.60.6-0.6-0.20.2-0.20.2-0.20.2-0.1-0.2-0.2
Lifetime Intake0.70.91.10.7-0.70.71.1-1.11.1-1.11.1-1.10.90.8-1.0
Liver weight, left0.91.51.8-1.31.3-1.3-1.21.2-1.21.2-1.21.2-1.3-1.30.7
Liver weight, right0.50.81.4-1.21.2-1.2-0.80.8-0.80.8-0.80.8-0.7-0.90.3
Locomotor activity2.64.05.52.3-2.32.32.0-2.02.0-2.02.0-2.01.72.0-0.7
Locomotor testing distance1.02.53.51.9-1.81.81.6-1.61.6-1.61.6-1.61.21.6-0.5
Locomotor testing rearing0.00.10.30.0-0.00.00.3-0.30.3-0.30.3-0.3-0.00.3-0.6
Locomotion in novel chamber1.11.51.81.0-1.01.01.3-1.31.3-1.31.3-1.31.01.3-1.2
Locomotion in novel chamber post-restriction0.72.12.61.3-1.31.31.5-1.51.5-1.51.5-1.51.61.4-1.5
Fecal boli incidents, locomotor time 10.61.62.0-1.41.4-1.4-1.21.2-1.21.2-1.21.2-1.1-1.31.1
Change in fecal boli incidents, locomotor task0.20.20.20.4-0.40.40.5-0.50.5-0.50.5-0.50.30.4-0.0
Time >=10cm from walls, locomotor time 10.50.61.9-0.60.6-0.6-0.70.7-0.70.7-0.70.7-1.1-0.61.4
Bouts of movement, locomotor time 10.30.50.80.6-0.60.60.7-0.70.7-0.70.7-0.70.90.7-0.7
Total resting periods, locomotor time 10.50.50.90.7-0.70.70.7-0.70.7-0.70.7-0.70.90.7-0.7
Rest time, locomotor task time 10.20.30.80.7-0.60.60.5-0.50.5-0.50.5-0.50.90.4-0.2
Distance moved, locomotor task time 10.41.22.3-0.80.9-0.9-1.11.1-1.11.1-1.11.1-1.4-1.01.5
Vertical activity count, locomotor time 10.00.20.6-0.70.7-0.7-0.30.3-0.30.3-0.30.3-0.8-0.30.0
Time >=10cm from walls, locomotor time 20.41.22.1-1.41.4-1.4-0.90.9-0.90.9-0.90.9-1.2-0.90.7
Bouts of movement, locomotor time 20.10.20.70.8-0.80.80.3-0.30.3-0.30.3-0.30.40.30.2
Total resting periods, locomotor time 20.00.20.60.8-0.70.70.2-0.20.2-0.20.2-0.20.40.30.3
Rest time, locomotor task time 20.30.51.01.0-1.01.00.6-0.60.6-0.60.6-0.60.80.7-0.2
Distance moved, locomotor task time 20.50.60.9-0.90.9-0.9-0.70.7-0.70.7-0.70.7-0.8-0.70.4
Vertical activity count, locomotor time 20.20.41.0-1.00.9-0.9-0.50.5-0.50.5-0.50.5-0.4-0.5-0.1
Light reinforcement 12.19.712.93.6-3.63.53.1-3.13.1-3.13.1-3.12.93.1-1.9
Light reinforcement 21.12.43.41.9-1.81.81.5-1.51.5-1.51.5-1.51.51.5-0.9
Bone: marrow area0.20.40.5-0.50.6-0.6-0.70.7-0.70.7-0.70.7-0.5-0.70.6
Bone: maximum diameter0.61.12.01.4-1.41.41.0-1.01.0-1.01.0-1.01.01.0-0.3
Bone: maximum force1.32.62.7-1.51.5-1.5-1.61.6-1.61.6-1.61.6-1.6-1.61.5
Bone: maximum moment1.22.22.3-1.41.4-1.4-1.51.5-1.51.5-1.51.5-1.5-1.51.4
Mean time between licks in bursts1.16.46.72.5-2.52.52.6-2.62.6-2.62.6-2.62.32.6-2.2
Mean num. licks in bursts0.00.10.2-0.10.1-0.1-0.30.3-0.30.3-0.30.3-0.1-0.30.4
Cd content in liver0.10.20.20.5-0.50.50.4-0.40.4-0.40.4-0.40.20.4-0.1
Co content in liver1.72.02.31.3-1.31.31.5-1.51.5-1.51.5-1.51.21.5-1.4
Cu content in liver0.10.10.40.6-0.60.60.2-0.20.2-0.20.2-0.20.30.20.4
Fe content in liver0.20.30.60.4-0.40.40.5-0.50.5-0.50.5-0.50.80.5-0.6
K content in liver0.10.10.40.3-0.20.2-0.10.1-0.10.1-0.10.1-0.2-0.10.6
Mg content in liver0.20.20.40.6-0.60.60.5-0.50.5-0.50.5-0.50.30.5-0.1
Mn content in liver0.91.02.31.5-1.41.40.8-0.80.8-0.80.8-0.81.10.80.2
Na content in liver1.11.32.7-0.70.8-0.8-1.21.2-1.21.2-1.21.2-1.1-1.21.6
Rb content in liver0.10.10.70.3-0.20.2-0.20.2-0.20.2-0.20.2-0.2-0.20.8
Se content in liver0.30.30.80.6-0.60.60.5-0.50.5-0.50.5-0.50.90.5-0.4
Sr content in liver0.00.00.1-0.20.1-0.10.0-0.00.0-0.00.0-0.00.00.0-0.3
Zn content in liver4.65.48.01.8-1.91.92.4-2.42.4-2.42.4-2.42.12.4-2.8
Bone: minimum diameter0.00.10.2-0.10.1-0.1-0.30.3-0.30.3-0.30.3-0.1-0.30.5
Time in familiar zone, hab. session 12.22.53.71.4-1.51.51.5-1.51.5-1.51.5-1.51.91.5-1.7
Time in novel zone, hab. session 11.31.52.3-1.01.0-1.0-1.21.2-1.21.2-1.21.2-1.5-1.21.5
Total zone transitions, hab. session 10.50.81.91.4-1.31.30.7-0.70.7-0.70.7-0.70.80.70.3
Total locomotion distance, hab. session 10.70.92.51.6-1.51.50.7-0.70.7-0.70.7-0.71.00.70.6
Locomotion velocity, hab. session 11.11.53.41.9-1.81.81.0-1.01.0-1.01.0-1.01.31.00.3
Time in familiar zone, hab. session 26.87.78.62.6-2.62.62.8-2.82.8-2.82.8-2.82.92.8-2.9
Time in novel zone, hab. session 25.25.76.4-2.22.2-2.2-2.42.4-2.42.4-2.42.4-2.5-2.42.5
Total zone transitions, hab. session 20.70.94.20.00.1-0.1-0.90.9-0.90.9-0.90.9-1.0-0.92.0
Total locomotion distance, hab. session 20.70.92.41.5-1.51.50.7-0.70.7-0.70.7-0.70.70.70.3
Locomotion velocity, hab. session 20.60.92.51.6-1.51.50.6-0.60.6-0.60.6-0.60.60.60.6
Novel to familiar place preference ratio4.15.47.1-2.02.1-2.1-2.42.4-2.42.4-2.42.4-2.4-2.42.7
Novelty place preference2.63.34.8-1.51.6-1.6-1.91.9-1.91.9-1.91.9-1.8-1.92.2
Time in novel zone, NPP test3.13.74.9-1.71.7-1.7-2.02.0-2.02.0-2.02.0-1.9-2.02.2
Total zone transitions, NPP test0.20.31.60.3-0.20.2-0.40.4-0.40.4-0.40.4-0.4-0.41.3
Total locomotion distance, NPP test0.20.31.50.3-0.20.2-0.50.5-0.50.5-0.50.5-0.3-0.51.2
Locomotion velocity, NPP test0.10.21.00.5-0.50.5-0.20.2-0.20.2-0.20.2-0.1-0.21.0
Intraocular pressure0.10.21.5-0.30.2-0.20.4-0.40.4-0.40.4-0.40.30.4-1.2
Delta distance traveled before/after self-admin0.40.50.80.7-0.70.70.7-0.70.7-0.70.7-0.70.80.9-0.7
Delta ambulatory time before/after self-admin0.20.40.70.7-0.70.70.6-0.60.6-0.60.6-0.60.80.8-0.5
Parametrial fat weight0.00.00.10.1-0.10.1-0.10.1-0.10.1-0.10.1-0.1-0.10.4
Pavlov. Cond. lever latency0.10.21.0-0.30.3-0.30.3-0.30.3-0.30.3-0.3-0.10.3-1.0
Pavlov. Cond. magazine entry latency3.24.25.52.2-2.22.22.0-2.02.0-2.02.0-2.02.32.0-1.6
Pavlov. Cond. change in total contacts0.10.10.30.4-0.30.30.2-0.20.2-0.20.2-0.20.50.20.0
Pavlov. Cond. index score0.40.51.11.0-1.01.00.5-0.50.5-0.50.5-0.51.10.5-0.1
Pavlov. Cond. latency score0.30.41.01.0-1.01.00.4-0.40.4-0.40.4-0.41.00.40.2
Pavlov. Cond. lever contacts0.10.20.90.3-0.20.2-0.30.3-0.30.3-0.30.30.1-0.30.9
Pavlov. Cond. magazine entry number0.91.11.8-1.21.2-1.2-1.01.0-1.01.0-1.01.0-1.3-1.00.9
Pavlov. Cond. intertrial magazine entries0.20.30.90.2-0.20.20.6-0.60.6-0.60.6-0.60.40.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.61.31.1-1.11.10.6-0.60.6-0.60.6-0.61.20.6-0.2
Pavlov. Cond. response bias0.91.11.91.2-1.21.21.0-1.01.0-1.01.0-1.01.41.0-0.8
Pavlov. Cond. lever latency0.71.01.2-0.80.9-0.9-1.11.1-1.11.1-1.11.1-0.8-1.11.0
Pavlov. Cond. magazine entry latency0.30.50.60.7-0.70.70.7-0.70.7-0.70.7-0.70.80.7-0.6
Pavlov. Cond. change in total contacts0.40.91.10.7-0.70.71.0-1.01.0-1.01.0-1.00.61.0-1.0
Pavlov. Cond. index score0.60.91.00.8-0.80.81.0-1.01.0-1.01.0-1.00.91.0-1.0
Pavlov. Cond. latency score0.50.81.00.8-0.80.81.0-1.01.0-1.01.0-1.00.81.0-0.8
Pavlov. Cond. lever contacts0.60.81.10.7-0.70.71.0-1.01.0-1.01.0-1.00.81.0-1.1
Pavlov. Cond. magazine entry number0.60.81.1-0.90.9-0.9-0.90.9-0.90.9-0.90.9-1.0-0.90.8
Pavlov. Cond. intertrial magazine entries0.10.30.6-0.80.7-0.7-0.50.5-0.50.5-0.50.5-0.6-0.50.0
Pavlov. Cond. lever-magazine prob. diff.0.60.91.00.8-0.80.81.0-1.01.0-1.01.0-1.00.91.0-0.9
Pavlov. Cond. response bias1.72.32.71.2-1.31.31.6-1.61.6-1.61.6-1.61.41.6-1.7
Time in closed arm before self-admin0.40.71.7-0.40.5-0.5-0.90.9-0.90.9-0.90.9-0.7-0.81.3
Time in closed arm after self-admin0.20.30.60.3-0.30.30.5-0.50.5-0.50.5-0.50.50.6-0.8
Time in open arm before self-admin0.10.10.30.3-0.30.30.4-0.40.4-0.40.4-0.40.20.6-0.2
Time in open arm after self-admin1.01.21.2-1.11.1-1.1-1.11.1-1.11.1-1.11.1-1.1-1.00.8
Bone: periosteal estimation0.30.71.4-0.50.6-0.6-0.90.9-0.90.9-0.90.9-0.8-0.91.2
Bone: periosteal perimeter0.00.10.20.5-0.40.40.1-0.10.1-0.10.1-0.10.10.10.4
Bone: post-yield work0.50.91.1-1.01.0-1.0-1.01.0-1.01.0-1.01.0-0.7-1.00.6
Progressive ratio test 1 active lever presses0.20.31.10.1-0.10.10.6-0.60.6-0.60.6-0.60.60.3-1.0
Progressive ratio test 1 breakpoint0.10.31.00.0-0.10.10.5-0.50.5-0.50.5-0.50.60.3-1.0
Progressive ratio test 1 inactive lever presses0.20.50.80.5-0.60.60.7-0.70.7-0.70.7-0.70.80.6-0.9
Progressive ratio test 2 active lever presses0.50.71.60.2-0.20.30.9-0.90.9-0.90.9-0.90.70.7-1.3
Progressive ratio test 2 breakpoint0.60.81.80.3-0.30.31.0-1.01.0-1.01.0-1.00.80.7-1.3
Progressive ratio test 2 inactive lever presses0.10.30.40.3-0.40.40.6-0.60.6-0.60.6-0.60.40.4-0.4
Incentive Sensitization - Responses0.00.10.4-0.30.3-0.30.3-0.30.3-0.30.3-0.30.10.2-0.7
Incentive Sensitization - Breakpoint0.10.10.5-0.20.1-0.10.4-0.40.4-0.40.4-0.40.20.3-0.7
Sum of active levers in priming session hrs 5-60.00.00.0-0.10.1-0.1-0.10.1-0.10.1-0.10.1-0.2-0.00.1
Progressive ratio0.10.20.3-0.60.6-0.5-0.50.5-0.50.5-0.50.5-0.3-0.50.1
Food seeking constrained by brief footshock0.20.30.60.7-0.70.70.5-0.50.5-0.50.5-0.50.80.3-0.1
Seeking ratio, punishment vs. effort0.10.30.60.8-0.80.80.5-0.50.5-0.50.5-0.50.60.4-0.0
Retroperitoneal fat weight0.31.32.0-1.41.4-1.4-1.11.1-1.11.1-1.11.1-0.9-1.20.2
Reaction time number correct0.10.41.1-1.11.0-1.0-0.50.5-0.50.5-0.50.5-0.3-0.4-0.6
Reaction time mean minus median0.10.70.90.7-0.70.80.9-0.90.9-0.90.9-0.90.90.9-1.0
Reaction time mean minus median AUC0.00.10.30.0-0.00.0-0.30.3-0.30.3-0.30.3-0.0-0.30.6
Reaction time num false alarms0.10.10.5-0.70.6-0.6-0.20.2-0.20.2-0.20.2-0.2-0.2-0.4
Reaction time num false alarms AUC0.10.20.5-0.70.7-0.7-0.20.2-0.20.2-0.20.2-0.2-0.2-0.5
Reaction time trials correct on left0.10.41.1-1.11.0-1.0-0.50.5-0.50.5-0.50.5-0.3-0.4-0.6
Reaction time trials on left0.10.41.1-1.11.0-1.0-0.50.5-0.50.5-0.50.5-0.3-0.5-0.5
Reaction time mean0.00.10.2-0.20.2-0.2-0.30.3-0.30.3-0.30.3-0.3-0.30.5
Reaction time mean AUC0.00.10.3-0.20.3-0.3-0.30.3-0.30.3-0.30.3-0.5-0.30.5
Median of all reaction times0.30.50.9-0.60.6-0.6-0.70.7-0.70.7-0.70.7-0.8-0.70.9
Reaction time omissions0.10.10.20.5-0.50.50.2-0.20.2-0.20.2-0.20.10.20.2
Reaction time false alarm rate0.00.00.1-0.30.3-0.3-0.20.2-0.20.2-0.20.2-0.2-0.20.1
Reaction time premature initiation rate1.01.52.01.0-1.11.11.3-1.31.3-1.31.3-1.31.11.3-1.4
Reaction time premature initiations0.41.33.40.6-0.60.71.2-1.21.2-1.21.2-1.21.11.2-1.8
Std. dev. reaction times0.00.10.10.3-0.30.30.4-0.40.4-0.40.4-0.40.40.4-0.3
Reaction time trials completed0.10.41.1-1.11.0-1.0-0.50.5-0.50.5-0.50.5-0.3-0.5-0.5
Reaction time trials AUC0.10.41.1-1.11.0-1.0-0.40.4-0.40.4-0.40.4-0.3-0.4-0.7
Run reversals in cocaine runway, females0.40.40.80.9-0.90.90.6-0.60.6-0.60.6-0.60.80.5-0.2
Run reversals in cocaine runway, males1.51.62.31.5-1.51.51.2-1.21.2-1.21.2-1.21.31.1-0.7
Latency to leave start box in cocaine runway0.20.30.60.7-0.70.70.5-0.50.5-0.50.5-0.5-0.10.40.3
Latency to leave start box in cocaine runway, F0.20.31.90.00.1-0.1-0.20.2-0.20.2-0.20.2-1.1-0.51.4
Latency to leave start box in cocaine runway, M1.91.82.31.3-1.31.31.3-1.31.3-1.31.3-1.31.41.5-1.5
Std. dev. time between licks in bursts0.40.70.90.9-0.90.90.8-0.80.8-0.80.8-0.80.70.8-0.5
Total sessions with >9 infusions0.50.60.80.4-0.40.40.9-0.90.9-0.90.9-0.90.70.6-0.9
Short access day 1 total inactive lever presses0.30.60.70.6-0.60.60.8-0.80.8-0.80.8-0.80.80.7-0.7
Short access day 10 total inactive lever presses0.00.00.1-0.20.2-0.20.2-0.20.2-0.20.2-0.20.00.3-0.4
Short access day 1 total infusions0.30.50.60.7-0.70.70.8-0.80.8-0.80.8-0.80.80.6-0.6
Short access day 10 total infusions0.10.20.60.1-0.10.20.5-0.50.5-0.50.5-0.50.50.2-0.8
Short access total infusions0.40.60.80.5-0.50.50.9-0.90.9-0.90.9-0.90.70.5-0.8
Short access day 1 locomotion1.22.02.31.3-1.31.31.5-1.51.5-1.51.5-1.51.41.3-1.3
Short access day 10 total locomotion2.39.410.92.5-2.62.63.3-3.33.3-3.33.3-3.33.03.0-3.2
Short access total locomotion2.33.64.31.5-1.51.62.1-2.12.1-2.12.1-2.11.81.7-1.8
One hour access (0.3 mA shock)0.00.00.1-0.20.2-0.20.1-0.10.1-0.10.1-0.10.1-0.1-0.3
Compulsive drug intake1.21.83.4-1.01.0-1.0-1.31.3-1.31.3-1.31.3-1.5-1.41.9
One hour access (shock baseline)0.30.92.10.6-0.70.71.0-1.01.0-1.01.0-1.01.10.8-1.4
Social response proportion0.60.71.31.1-1.11.10.8-0.80.8-0.80.8-0.80.70.8-0.3
Social responses6.38.210.03.2-3.13.12.9-2.92.9-2.92.9-2.92.62.9-1.9
Social time0.40.61.3-0.70.7-0.7-0.70.7-0.70.7-0.70.7-1.1-0.70.7
Soleus weight8.525.027.3-5.25.2-5.2-5.05.0-5.05.0-5.05.0-5.0-5.03.9
Bone: stiffness2.74.85.1-2.12.1-2.1-2.32.3-2.32.3-2.32.3-2.2-2.32.1
Tibialis anterior weight1.13.84.1-2.02.0-2.0-2.02.0-2.02.0-2.02.0-1.8-2.01.5
Time to tail flick, vehicle, before self-admin0.00.00.10.3-0.30.30.1-0.10.1-0.10.1-0.10.20.20.1
Time to tail flick, vehicle, after self-admin0.30.62.20.4-0.50.50.7-0.70.7-0.70.7-0.70.90.7-1.5
Time to tail flick, test, before self-admin0.20.20.40.7-0.60.60.3-0.30.3-0.30.3-0.30.30.50.1
Time to tail flick, test, after self-admin0.10.10.20.3-0.40.40.2-0.20.2-0.20.2-0.20.50.3-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.60.5-0.5-0.10.1-0.10.1-0.10.1-0.0-0.3-0.7
Delta time to tail flick, test, before/after SA0.10.10.6-0.10.1-0.10.2-0.20.2-0.20.2-0.20.40.2-0.8
Tibia length0.92.42.61.5-1.51.51.6-1.61.6-1.61.6-1.61.41.6-1.4
Ambulatory time before self-admin0.10.20.4-0.40.5-0.5-0.40.4-0.40.4-0.40.4-0.6-0.60.6
Ambulatory time after self-admin0.00.00.10.00.0-0.00.0-0.00.0-0.00.0-0.0-0.1-0.00.2
Bone: tissue strength2.12.22.8-1.41.4-1.4-1.51.5-1.51.5-1.51.5-1.7-1.51.5
Total heroin consumption1.41.72.21.5-1.51.51.3-1.31.3-1.31.3-1.31.21.3-0.8
Bone: trabecular number0.20.40.91.0-0.90.90.4-0.40.4-0.40.4-0.40.60.40.3
Bone: trabecular spacing0.20.31.0-1.00.9-0.9-0.10.1-0.10.1-0.10.1-0.2-0.1-1.0
Bone: trabecular thickness0.60.84.90.2-0.10.1-0.70.7-0.70.7-0.70.7-0.9-0.72.2
Bone: trabecular tissue density1.01.72.1-1.51.5-1.5-1.31.3-1.31.3-1.31.3-1.3-1.30.9
Water consumed over 24 hours0.51.11.3-1.01.0-1.0-1.11.1-1.11.1-1.11.1-0.9-1.11.1
Number of responses in last shaping day1.82.32.71.2-1.21.21.6-1.61.6-1.61.6-1.61.61.4-1.6