Ndufaf8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	OFC	mRNA stability	Ndufaf8	0.24	0.14	9.2e-04	0.05	0.04	0.02	0.1	2.4e-02	4.5e-02	1.1e-01	2.8e-03
2	Brain	mRNA stability	Ndufaf8	0.04	0.03	7.3e-05	0.05	0.03	0.03	0.04	2.9e-05	3.5e-04	5.6e-04	2.2e-04
3	PL	mRNA stability	Ndufaf8	0.02	0.02	9.7e-03	0.01	0.01	0.01	0.01	4.2e-02	1.7e-02	2.0e-02	2.3e-02
4	Adipose	gene expression	Ndufaf8	0.07	0.05	7.7e-06	0.05	0.04	0.04	0.04	7.4e-06	9.7e-06	1.4e-05	1.6e-05
5	BLA	gene expression	Ndufaf8	0.14	0.08	7.3e-06	0.1	0.09	0.06	0.07	3.3e-06	2.4e-05	4.3e-04	1.7e-04
6	pVTA	gene expression	Ndufaf8	0.07	0.05	3.7e-03	0.07	0.05	0.03	0.07	4.5e-04	2.7e-03	1.3e-02	5.2e-04
7	Liver	mRNA stability	Ndufaf8	0.31	0.15	0.0e+00	0.22	0.23	0.22	0.22	2.0e-24	9.9e-25	1.5e-24	1.7e-24
8	Brain	gene expression	Ndufaf8	0.13	0.07	6.8e-08	0.08	0.09	0.09	0.09	1.3e-07	1.2e-08	2.2e-08	2.3e-08
9	Liver	gene expression	Ndufaf8	0.1	0.07	1.3e-07	0.03	0.06	0.06	0.06	4.7e-04	3.7e-07	3.7e-07	7.8e-07
10	NAcc	gene expression	Ndufaf8	0.14	0.07	3.0e-12	0.04	0.09	0.05	0.08	5.9e-05	1.2e-10	7.8e-07	5.3e-10
11	IL	gene expression	Ndufaf8	0.24	0.15	2.7e-03	0.05	0.11	0.12	0.12	2.7e-02	1.5e-03	7.1e-04	1.0e-03
12	PL	gene expression	Ndufaf8	0.13	0.09	3.5e-05	0.01	0.04	0.04	0.04	9.0e-03	2.6e-05	1.7e-05	4.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	0.2	0.4	0.9	0.1	-0.6	0.6	-0.4	-0.9	-0.7	-0.7	0.4	0.6	0.6	-0.5	-0.8
Area under the delay curve	0.9	0.9	3.0	-1.7	1.5	-1.6	1.3	0.8	0.7	0.8	0.3	-0.2	0.2	0.2	0.2
BMI with tail	1.0	3.2	5.5	1.1	-1.6	1.5	-2.1	-2.3	-2.3	-2.1	1.5	1.7	1.6	-1.4	-1.8
BMI without tail	6.8	14.1	25.8	3.0	-3.6	3.7	-4.1	-4.5	-5.1	-4.6	2.8	3.6	3.3	-2.8	-3.2
Body weight	2.0	8.3	22.7	4.2	-4.8	4.7	-2.8	-3.3	-3.2	-2.6	-0.5	1.0	0.2	-0.2	-0.7
Weight adjusted by age	1.8	2.0	5.7	2.4	-2.4	2.1	-1.5	-1.1	-1.9	-1.0	-0.3	0.3	0.1	-0.1	-0.8
Bone surface	0.1	0.3	0.6	0.3	-0.7	0.7	0.3	-0.1	0.2	0.1	-0.8	-0.4	-0.6	0.7	0.5
Bone volume	0.1	0.2	0.6	0.4	-0.8	0.7	-0.2	-0.6	-0.4	-0.4	-0.1	0.2	0.1	0.1	-0.2
Breakpoint value in progressive ratio session	0.3	0.4	1.1	1.0	-0.5	0.2	-1.1	-0.6	-0.7	-0.3	0.4	-0.1	-0.0	-0.2	-0.8
Number of licking bursts	0.1	0.1	0.6	0.4	-0.5	0.7	-0.2	-0.4	-0.2	-0.5	-0.0	0.4	0.1	-0.1	0.3
Context. condit. distance diff. score	2.8	3.4	5.3	0.8	-1.0	1.1	-2.2	-2.1	-2.1	-2.3	1.9	2.2	2.2	-1.7	-1.6
Locomotion velocity, session 1	3.6	3.8	6.2	-2.1	2.0	-2.1	2.5	2.5	2.3	2.3	-1.2	-1.8	-1.4	1.6	1.2
Locomotion distance, session 1	0.9	1.2	3.4	-1.6	1.8	-1.6	0.4	0.5	0.4	-0.0	1.3	0.9	1.2	-1.1	-0.4
Locomotion velocity, session 2	3.6	4.2	7.7	-2.8	2.7	-2.6	2.6	2.2	2.5	2.0	-0.5	-1.1	-0.7	1.2	1.6
Locomotion distance, session 2	0.3	0.5	1.1	-0.5	0.6	-0.5	-0.1	-0.3	-0.2	-0.6	1.1	1.0	1.1	-0.8	-0.4
Locomotion velocity, session 3	1.3	1.6	3.3	-1.3	1.7	-1.7	1.1	1.8	1.5	1.5	-0.5	-1.0	-0.7	0.8	0.6
Locomotion distance, session 3	1.4	1.5	4.5	-2.0	2.1	-2.1	1.1	1.3	1.2	1.0	0.5	-0.3	0.2	0.1	0.1
Stereotopy head waving bouts, day 3	0.7	0.9	1.7	-0.5	1.0	-1.0	0.8	1.3	1.3	1.1	-0.6	-0.9	-0.9	0.6	0.8
Stereotopy head waving duration, day 3	0.2	0.3	0.7	-0.1	0.7	-0.7	0.1	0.7	0.8	0.6	-0.2	-0.4	-0.4	0.3	0.6
Locomotion velocity, session 7	0.2	0.3	0.8	-0.8	0.9	-0.9	0.2	0.2	0.2	0.1	0.6	0.3	0.5	-0.3	-0.2
Locomotion distance, session 7	1.8	2.3	5.0	-1.9	1.7	-1.7	-0.2	-0.3	-0.3	-0.8	2.2	1.6	2.0	-1.7	-1.4
Stereotopy head waving bouts, day 7	0.3	0.3	1.0	0.7	-0.5	0.5	-1.0	-0.6	-0.6	-0.5	0.3	0.4	0.3	-0.1	-0.1
Stereotopy head waving duration, day 7	0.4	0.5	1.6	1.3	-0.7	0.9	-0.9	-0.1	-0.0	-0.1	-0.6	-0.2	-0.5	0.6	0.9
Locomotion velocity, session 8	0.7	0.9	2.1	-0.5	0.6	-0.4	-0.5	-0.7	-0.6	-0.9	1.5	1.4	1.4	-1.1	-0.6
Locomotion distance, session 8	3.8	5.6	10.0	0.5	-0.6	0.9	-2.5	-2.5	-2.5	-2.9	2.9	3.2	3.1	-2.5	-2.1
Degree of sensitization distance	1.5	1.6	2.8	0.9	-0.9	1.0	-1.5	-1.7	-1.4	-1.5	1.1	1.4	1.2	-1.2	-0.9
Degree of sensitization stereotypy	0.6	0.7	1.8	0.9	-0.8	0.8	-1.4	-1.0	-1.1	-0.9	0.6	0.7	0.6	-0.3	-0.4
Conditioned locomotion	3.6	4.2	7.1	2.5	-2.7	2.6	-2.6	-2.6	-2.4	-2.3	0.7	1.5	1.1	-1.2	-1.0
Cocaine response after cond. corrected	0.1	0.1	0.4	-0.2	0.3	-0.6	0.1	0.2	-0.1	0.3	0.2	-0.3	-0.0	-0.2	-0.6
Cocaine response after cond. not corrected	0.4	0.4	1.2	-0.8	0.9	-1.1	0.6	0.8	0.5	0.7	0.0	-0.5	-0.2	0.1	-0.1
Cocaine response before conditioning	0.4	0.5	1.1	-1.1	0.9	-0.7	0.7	0.8	0.9	0.4	-0.1	-0.0	0.0	0.4	0.8
Saline control response	1.3	1.7	5.2	2.0	-2.2	2.3	-1.2	-1.2	-1.3	-1.0	-0.5	0.2	-0.2	0.3	-0.2
Bone: connectivity density	0.1	0.2	0.4	-0.2	-0.1	0.2	-0.2	-0.6	-0.1	-0.6	0.4	0.7	0.6	-0.4	-0.0
Bone: cortical apparent density	1.2	1.5	4.7	-2.0	2.1	-2.2	0.9	1.3	1.2	1.1	0.4	-0.4	0.1	-0.3	-0.5
Bone: cortical area	2.6	3.9	11.9	3.4	-3.4	3.3	-1.7	-1.5	-1.6	-1.0	-1.3	-0.3	-0.9	0.8	0.5
Bone: cortical porosity	1.8	1.9	4.7	0.5	-0.6	0.2	1.1	1.0	0.9	1.6	-2.0	-2.2	-2.1	1.8	0.9
Bone: cortical porosity	1.1	1.1	2.8	0.7	-0.9	0.4	0.6	0.5	0.4	1.0	-1.6	-1.7	-1.7	1.4	0.6
Bone: cortical thickness	2.1	3.4	11.3	3.4	-3.0	2.8	-1.4	-0.9	-0.9	-0.3	-1.8	-1.0	-1.6	1.1	0.8
Bone: cortical thickness	0.7	0.8	2.6	1.6	-1.5	1.3	-0.7	-0.7	-1.0	-0.4	-0.4	-0.2	-0.4	0.0	-0.3
Bone: cortical tissue density	1.4	1.8	5.4	-2.1	2.2	-2.3	1.0	1.4	1.3	1.2	0.4	-0.5	0.0	-0.3	-0.5
Condit. Reinf. active minus inactive responses	1.4	1.6	3.2	1.8	-1.8	1.8	-1.5	-1.5	-1.6	-1.3	0.2	0.7	0.4	-0.4	-0.5
Condit. Reinf. active-inactive response ratio	0.9	1.0	1.7	1.2	-1.2	1.1	-1.2	-1.3	-1.3	-1.1	0.5	0.6	0.5	-0.7	-0.9
Condit. Reinf. active responses	2.3	2.8	6.4	2.4	-2.5	2.5	-1.9	-1.9	-2.0	-1.7	0.1	0.8	0.4	-0.3	-0.4
Condit. Reinf. inactive responses	0.5	0.6	1.6	1.1	-1.2	1.3	-0.9	-0.9	-1.0	-0.8	-0.0	0.4	0.2	0.1	0.1
Incentive salience index mean	1.1	1.3	3.2	1.7	-1.7	1.8	-1.3	-1.3	-1.3	-1.2	0.1	0.6	0.3	-0.2	-0.1
Condit. Reinf. lever presses	0.2	0.2	0.5	0.4	-0.2	0.5	-0.7	-0.5	-0.4	-0.6	0.4	0.7	0.5	-0.3	0.3
Condit. Reinf. active minus inactive responses	0.6	0.7	2.4	1.6	-1.1	1.2	-1.2	-0.8	-0.6	-0.7	-0.1	0.4	0.0	-0.0	0.3
Condit. Reinf. active-inactive response ratio	1.0	1.0	3.5	1.9	-1.5	1.5	-0.8	-0.4	-0.4	-0.2	-1.0	-0.4	-0.8	0.8	0.8
Condit. Reinf. active responses	0.6	0.9	2.1	0.9	-0.6	0.5	-1.4	-1.2	-0.9	-1.0	0.9	0.9	0.8	-0.9	-0.6
Condit. Reinf. inactive responses	0.7	0.9	2.1	-0.6	0.7	-0.8	-0.7	-0.6	-0.5	-0.6	1.4	1.0	1.2	-1.4	-1.3
Condit. Reinf. lever presses	1.7	2.4	3.7	0.7	-0.7	0.5	-1.8	-1.8	-1.7	-1.6	1.7	1.6	1.6	-1.9	-1.9
Condit. Reinf. lever reinforcers received	1.4	2.0	3.7	0.9	-0.7	0.5	-1.9	-1.7	-1.5	-1.5	1.6	1.5	1.5	-1.6	-1.5
Conditioned reinforcement - actives	0.4	0.4	1.2	1.1	-0.5	0.8	-0.8	-0.8	-0.7	-0.6	0.2	0.7	0.3	-0.2	0.7
Conditioned reinforcement - inactives	0.8	0.8	2.7	1.5	-1.6	1.4	-0.8	-1.0	-1.0	-0.5	-0.4	-0.0	-0.2	0.4	-0.2
Conditioned locomotion	0.4	0.4	1.9	1.4	-0.8	1.0	-0.7	-0.4	-0.2	-0.2	-0.4	0.1	-0.2	-0.1	0.8
Patch foraging indifference point 0 sec	0.2	0.3	1.1	0.5	-0.3	0.3	-1.0	-0.9	-0.6	-0.5	0.5	0.3	0.3	-0.5	-0.7
Patch foraging indifference point AUC	0.1	0.1	0.4	0.1	0.1	-0.1	-0.2	-0.2	-0.0	-0.1	0.3	0.2	0.2	-0.6	-0.6
Delay disc. indifference point, 0s delay	0.0	0.0	0.1	0.2	-0.0	0.1	0.1	-0.2	-0.1	0.0	-0.1	0.1	0.0	0.2	0.3
Delay disc. indifference point, 16s delay	1.1	1.1	2.5	-1.2	0.9	-1.1	0.1	-0.4	-0.3	-0.6	1.6	1.3	1.6	-1.3	-1.1
Delay disc. indifference point, 2s delay	0.3	0.3	0.6	-0.6	0.6	-0.7	0.8	0.7	0.5	0.6	-0.2	-0.4	-0.2	0.8	0.6
Delay disc. indifference point, 24s delay	3.3	3.2	7.1	-2.7	2.5	-2.6	2.3	1.9	1.7	1.9	-0.3	-1.1	-0.4	0.9	0.8
Delay disc. indifference point, 4s delay	0.4	0.4	1.2	-0.7	1.1	-0.9	0.6	0.8	0.8	0.7	-0.1	-0.5	-0.3	0.2	0.4
Delay disc. indifference point, 8s delay	1.3	1.4	2.8	-1.5	1.3	-1.3	1.7	1.1	1.0	1.3	-0.6	-1.0	-0.6	1.1	0.9
Indifference point function ln k	0.3	0.4	1.4	-1.2	1.0	-1.1	0.3	0.0	0.3	0.1	0.8	0.3	0.6	-0.4	-0.3
Indifference point function log k	0.3	0.4	1.4	-1.2	1.0	-1.1	0.3	0.0	0.3	0.1	0.8	0.3	0.6	-0.4	-0.3
Patch foraging total patch changes 0 sec	0.5	0.8	1.9	0.5	-0.4	0.3	-1.4	-1.2	-0.9	-0.8	0.9	0.7	0.7	-0.9	-1.1
Patch foraging total patch changes 12 sec	0.0	0.0	0.2	0.1	0.1	-0.1	-0.4	-0.2	0.1	0.1	-0.0	-0.2	-0.2	-0.2	-0.5
Patch foraging total patch changes 18 sec	1.3	1.6	4.0	-0.1	0.1	-0.2	-1.3	-1.1	-0.9	-1.2	1.7	1.4	1.5	-1.8	-2.0
Patch foraging total patch changes 24 sec	1.0	1.2	2.0	1.4	-1.2	1.1	-1.3	-1.4	-1.2	-1.0	0.6	0.8	0.6	-0.9	-1.1
Patch foraging total patch changes 6 sec	0.2	0.3	0.7	0.8	-0.6	0.7	-0.4	-0.2	-0.1	0.2	-0.7	-0.5	-0.7	0.4	0.0
Patch foraging time to switch 0 sec	0.5	0.8	2.2	-1.4	0.8	-1.0	1.5	1.3	0.8	0.8	-0.4	-0.6	-0.3	0.7	0.4
Patch foraging water rate 0 sec	3.0	4.8	9.1	2.9	-2.1	2.2	-3.0	-3.0	-2.5	-2.3	1.3	1.7	1.3	-1.6	-1.4
Patch foraging water rate 12 sec	1.8	2.8	4.9	1.0	-0.7	0.6	-2.1	-2.2	-1.7	-1.9	2.0	1.9	1.8	-1.8	-1.2
Patch foraging water rate 18 sec	2.2	2.9	6.1	2.0	-1.2	1.4	-2.5	-2.2	-1.7	-2.0	1.5	1.8	1.4	-1.6	-0.4
Patch foraging water rate 24 sec	6.6	9.1	16.5	2.6	-2.1	2.0	-4.1	-3.9	-3.4	-3.4	2.8	3.0	2.8	-3.0	-2.5
Patch foraging water rate 6 sec	0.6	0.9	1.8	0.9	-0.5	0.6	-1.3	-1.4	-0.8	-1.2	1.0	1.1	0.9	-1.0	-0.1
Seeking ratio, delayed vs. immediate footshock	0.6	0.7	2.2	1.2	-1.3	1.5	-0.5	-0.5	-0.9	-0.6	-0.5	0.1	-0.1	0.7	0.2
Distance traveled before self-admin	0.4	0.4	1.3	0.8	-1.2	0.8	-0.5	-0.4	-0.9	-0.2	-0.4	-0.4	-0.4	0.9	-0.0
Distance traveled after self-admin	1.5	1.6	2.8	1.0	-0.9	0.8	-1.7	-1.5	-1.5	-1.5	1.3	1.3	1.2	-1.2	-1.4
Extensor digitorum longus weight	1.1	4.2	6.4	0.2	-0.6	0.7	-2.1	-2.4	-2.3	-2.4	2.4	2.5	2.5	-2.3	-2.2
Bone: elastic displacement	0.6	0.7	3.0	1.7	-1.2	1.1	-1.3	-0.6	-0.5	-0.3	-0.5	-0.3	-0.6	-0.1	-0.0
Bone: elastic work	2.5	3.2	9.8	3.1	-2.9	2.5	-1.5	-0.7	-0.9	-0.0	-1.9	-1.4	-1.9	1.1	0.3
Bone: endosteal estimation	0.5	1.0	1.9	-0.2	-0.2	0.3	-0.5	-1.0	-1.2	-1.2	1.2	1.3	1.4	-1.1	-1.2
Bone: endosteal perimeter	0.3	0.5	1.8	0.8	-1.4	1.4	0.3	-0.3	-0.6	-0.3	-0.8	-0.2	-0.4	0.7	0.4
Epididymis fat weight	1.2	2.8	4.7	1.9	-1.9	2.1	-1.9	-2.2	-2.0	-1.9	0.8	1.4	1.0	-1.1	-1.0
Delta time in closed arm before/after self-admin	0.6	0.5	2.6	0.4	-0.3	0.5	0.4	0.6	0.9	0.4	-1.0	-0.3	-0.7	0.5	1.6
Delta time in open arm before/after self-admin	1.1	1.0	1.6	0.5	-0.4	0.2	-1.0	-1.2	-1.3	-1.0	1.3	1.1	1.2	-1.0	-1.2
Diff in mean of infusions in LGA sessions	0.0	0.1	0.2	0.0	0.5	-0.4	0.0	0.3	0.2	0.3	0.0	-0.2	-0.1	0.1	-0.0
Delay discount exponential model param	1.5	1.6	4.2	2.1	-1.9	1.9	-1.6	-1.2	-1.1	-1.2	-0.1	0.5	0.0	-0.4	-0.3
Extinction: sum of active levers before priming	0.5	0.5	2.0	-1.0	1.2	-1.4	0.4	0.7	0.7	0.6	0.5	-0.3	-0.0	-0.1	0.1
Active lever presses in extinction session 6	0.1	0.1	0.4	0.7	0.1	-0.5	-0.5	-0.1	-0.2	0.4	0.2	-0.4	-0.2	0.1	-0.1
Bone: final force	2.4	3.9	11.5	3.2	-3.4	3.2	-1.8	-1.8	-2.2	-1.4	-0.7	0.2	-0.3	0.3	-0.3
Bone: final moment	2.7	4.3	13.0	3.4	-3.6	3.4	-2.0	-1.9	-2.3	-1.4	-0.8	0.0	-0.5	0.4	-0.4
Food consumed during 24 hour testing period	0.8	1.0	3.4	1.5	-0.9	0.9	-1.9	-1.1	-0.9	-0.9	0.6	0.6	0.4	-0.7	-0.3
Glucose	3.6	5.3	9.7	-2.1	2.6	-3.1	2.1	2.9	2.6	3.0	-1.2	-2.6	-1.9	1.6	0.9
Heart weight	0.3	0.4	0.9	0.8	-0.6	0.7	-0.7	-0.7	-1.0	-0.6	0.2	0.3	0.3	-0.4	-0.6
Delay discount hyperbolic model param	1.4	1.4	3.8	1.9	-1.9	1.9	-1.5	-1.2	-1.1	-1.1	-0.1	0.5	0.0	-0.4	-0.3
Intermittent access intake day 1-15 change	0.2	0.2	0.7	0.2	-0.8	0.5	-0.2	-0.4	-0.4	-0.3	-0.2	-0.2	-0.1	0.3	-0.4
Intermittent access intake escalation	0.2	0.2	0.8	0.4	-0.9	0.7	-0.3	-0.5	-0.6	-0.4	-0.0	0.1	0.1	0.2	-0.3
Intermittent access intake escalation 2	0.6	0.6	2.0	0.7	-1.4	1.0	-0.0	-0.4	-0.4	-0.0	-0.8	-0.7	-0.7	1.3	0.1
Intermitt. access day 1 inactive lever presses	0.7	0.8	2.5	1.6	-1.2	1.1	-1.0	-1.0	-1.3	-0.4	-0.2	0.0	-0.1	0.0	-0.6
Intermitt. access day 15 inactive lever presses	1.7	1.8	3.5	1.8	-1.8	1.6	-1.8	-1.9	-1.6	-1.4	0.6	1.0	0.7	-0.5	-0.2
Intermitt. access escalation Index	1.3	1.1	2.5	1.5	-1.4	1.6	-1.1	-1.1	-1.2	-1.2	0.3	1.1	0.7	-0.4	0.2
Intermittent access day 1 total infusions	0.1	0.2	0.4	0.6	-0.5	0.6	-0.6	-0.3	-0.3	-0.4	-0.0	0.2	0.0	-0.2	-0.4
Intermittent access day 15 total infusions	0.4	0.5	1.1	1.0	-1.1	1.1	-0.7	-0.6	-0.9	-0.7	-0.0	0.4	0.2	-0.1	-0.4
Intermittent access terminal intake (last 3 days)	0.6	0.6	1.9	1.3	-1.4	1.4	-0.7	-0.7	-0.7	-0.5	-0.4	0.1	-0.2	0.2	-0.1
Intermittent access total infusions	0.3	0.4	0.9	1.0	-0.9	0.9	-0.8	-0.6	-0.7	-0.6	-0.1	0.3	0.1	-0.1	-0.1
Intermittent access day 1 locomotion	0.4	0.5	1.1	1.0	-0.9	1.0	-0.8	-0.7	-0.7	-0.6	0.0	0.5	0.3	-0.4	-0.3
Intermittent access day 15 total locomotion	0.2	0.3	0.7	0.8	-0.7	0.8	-0.2	-0.1	-0.1	0.1	-0.8	-0.4	-0.6	0.3	0.3
Intermittent access total locomotion	0.3	0.4	1.3	1.1	-1.0	1.0	-0.7	-0.6	-0.4	-0.4	-0.3	0.1	-0.2	-0.1	0.1
Intermittent access standard deviation	0.7	0.7	1.4	-0.5	0.7	-0.9	0.7	1.0	0.9	1.1	-0.6	-1.2	-0.9	1.1	0.5
Left kidney weight	0.6	1.6	3.5	0.6	-0.2	0.5	1.0	1.3	1.0	1.2	-1.9	-1.4	-1.7	1.5	1.6
Right kidney weight	0.3	0.9	2.2	0.5	0.1	0.4	0.5	1.2	1.0	0.9	-1.4	-0.9	-1.2	0.8	1.5
Cocaine induced anxiety	1.6	1.9	5.2	2.3	-2.1	1.8	-1.3	-1.3	-1.4	-0.2	-0.9	-0.8	-1.0	1.2	-0.2
Post-drug Anxiety	0.2	0.2	0.9	0.6	-0.5	0.1	-0.6	-1.0	-0.5	-0.0	0.1	-0.4	-0.3	0.4	-0.6
Baseline Anxiety	3.0	3.2	8.8	-3.0	2.9	-2.8	1.9	1.7	2.1	1.0	0.8	0.1	0.5	-0.6	0.4
Tail length	3.1	9.4	24.9	4.5	-4.7	5.0	-2.8	-3.2	-3.7	-3.1	-0.0	1.7	0.8	-0.8	-0.7
Length with tail	1.2	4.4	13.5	3.4	-3.5	3.7	-0.6	-1.0	-0.9	-0.5	-2.3	-0.8	-1.7	1.3	1.2
Length without tail	2.7	5.9	10.6	-0.1	0.4	-0.5	2.1	2.2	2.9	2.8	-3.2	-3.0	-3.3	2.7	2.7
Times rat made contact with spout	0.7	0.9	2.5	1.6	-0.9	0.8	-1.0	-0.1	0.2	0.5	-1.0	-1.1	-1.3	0.8	0.7
Lifetime Intake	0.1	0.1	0.3	0.5	-0.5	0.5	-0.4	-0.2	-0.2	-0.2	-0.2	0.1	-0.0	0.1	0.1
Liver weight, left	0.6	1.0	1.7	-0.2	0.5	-0.5	0.7	1.2	1.0	1.3	-1.1	-1.3	-1.3	1.1	0.7
Liver weight, right	1.4	2.3	5.4	2.1	-2.2	2.3	-0.2	-0.1	-0.0	-0.0	-1.9	-0.7	-1.4	1.7	2.1
Locomotor activity	0.2	0.3	1.1	-0.8	1.0	-1.1	0.4	0.6	0.6	0.4	0.3	-0.1	0.1	-0.3	-0.3
Locomotor testing distance	0.2	0.4	0.9	-0.4	0.7	-0.8	-0.2	0.1	-0.0	-0.1	0.9	0.6	0.8	-1.0	-0.8
Locomotor testing rearing	0.6	1.0	2.2	0.6	0.2	-0.3	-1.5	-1.1	-0.8	-0.8	1.4	1.1	1.1	-1.4	-0.6
Locomotion in novel chamber	0.2	0.3	0.8	0.3	0.1	0.0	-0.4	-0.3	-0.2	-0.5	0.7	0.8	0.7	-0.9	-0.3
Locomotion in novel chamber post-restriction	0.4	0.5	1.9	0.8	-1.3	1.4	-0.2	-0.6	-0.4	-0.4	-0.8	-0.3	-0.5	0.7	0.3
Fecal boli incidents, locomotor time 1	0.1	0.2	0.5	-0.5	0.5	-0.7	0.2	0.3	0.5	0.2	0.3	0.2	0.3	-0.4	0.2
Change in fecal boli incidents, locomotor task	3.0	2.9	6.1	-2.5	1.9	-2.2	2.0	1.8	1.8	1.8	-0.6	-1.6	-1.1	1.2	0.4
Time >=10cm from walls, locomotor time 1	0.7	0.7	1.6	-0.0	-0.4	0.6	-1.0	-0.9	-0.4	-1.3	0.9	1.1	0.9	-1.1	-0.3
Bouts of movement, locomotor time 1	1.1	1.2	3.7	-1.9	1.9	-1.7	1.2	1.0	1.1	0.8	0.2	-0.3	0.1	0.2	0.0
Total resting periods, locomotor time 1	1.7	1.9	4.9	-2.1	2.2	-1.9	1.5	1.4	1.5	1.3	-0.1	-0.8	-0.4	0.6	0.4
Rest time, locomotor task time 1	0.7	0.8	1.2	-0.6	0.8	-0.6	1.0	1.1	0.8	1.1	-0.8	-1.0	-0.9	0.9	0.7
Distance moved, locomotor task time 1	0.6	0.7	1.1	0.8	-1.1	1.1	-0.8	-0.9	-0.8	-0.9	0.3	0.7	0.5	-0.9	-0.8
Vertical activity count, locomotor time 1	2.0	2.1	3.4	1.2	-1.7	1.5	-1.7	-1.9	-1.5	-1.8	1.0	1.5	1.2	-1.3	-0.9
Time >=10cm from walls, locomotor time 2	0.4	0.4	1.8	0.1	0.0	0.3	0.3	0.8	0.9	0.4	-0.8	-0.4	-0.7	0.5	1.3
Bouts of movement, locomotor time 2	0.6	0.7	2.3	-1.5	1.4	-1.3	0.8	0.6	0.5	0.3	0.5	0.2	0.4	-0.1	-0.1
Total resting periods, locomotor time 2	0.4	0.4	1.3	-1.1	1.1	-0.9	0.5	0.3	0.3	0.0	0.6	0.4	0.6	-0.2	-0.0
Rest time, locomotor task time 2	0.3	0.3	0.7	-0.6	0.8	-0.3	0.6	0.5	0.7	0.5	-0.5	-0.4	-0.5	0.4	0.7
Distance moved, locomotor task time 2	0.1	0.1	0.3	0.5	-0.6	0.5	0.0	0.1	-0.1	-0.0	-0.3	0.1	-0.1	-0.3	-0.3
Vertical activity count, locomotor time 2	0.7	0.7	1.2	0.7	-0.9	0.7	-0.8	-0.7	-0.9	-1.0	0.7	1.1	0.9	-1.1	-0.6
Light reinforcement 1	2.1	3.8	8.1	2.4	-1.8	2.1	-2.9	-2.1	-2.1	-2.2	1.2	1.9	1.4	-1.6	-0.6
Light reinforcement 2	1.7	2.2	6.1	2.5	-2.1	2.4	-1.8	-1.5	-1.4	-1.5	0.0	0.9	0.4	-0.4	0.2
Bone: marrow area	0.5	1.0	2.0	-0.2	-0.2	0.3	-0.5	-1.0	-1.2	-1.2	1.2	1.3	1.4	-1.1	-1.2
Bone: maximum diameter	0.7	1.3	4.1	1.8	-1.9	2.0	-0.4	-0.5	-0.6	-0.4	-1.1	-0.3	-0.8	0.9	0.9
Bone: maximum force	2.4	4.1	12.0	3.2	-3.5	3.4	-1.8	-1.9	-2.3	-1.6	-0.7	0.3	-0.2	0.3	-0.3
Bone: maximum moment	2.6	4.5	13.4	3.4	-3.7	3.5	-1.9	-2.0	-2.4	-1.5	-0.8	0.2	-0.3	0.3	-0.5
Mean time between licks in bursts	0.6	0.8	2.4	-1.3	1.6	-1.4	1.0	1.1	0.8	0.6	0.3	0.0	0.3	-0.2	0.1
Mean num. licks in bursts	0.1	0.2	0.4	0.7	-0.2	-0.1	-0.6	-0.0	-0.1	0.4	-0.2	-0.6	-0.5	0.2	-0.3
Cd content in liver	0.9	1.0	2.3	-1.1	1.5	-1.5	-0.4	-0.2	0.1	-0.1	1.5	0.8	1.1	-1.3	-1.0
Co content in liver	0.2	0.3	0.6	0.0	0.3	-0.3	-0.6	-0.6	-0.4	-0.4	0.8	0.5	0.6	-0.7	-0.7
Cu content in liver	0.8	1.0	2.4	0.3	-0.3	0.0	0.5	0.5	0.8	1.1	-1.3	-1.5	-1.5	1.4	0.8
Fe content in liver	0.3	0.4	1.2	-0.8	1.1	-1.0	0.3	0.5	0.4	0.2	0.6	0.3	0.4	-0.7	-0.5
K content in liver	1.4	1.4	3.9	1.7	-1.7	2.0	-1.4	-1.3	-1.2	-1.2	-0.0	0.8	0.3	-0.1	0.2
Mg content in liver	1.0	1.0	2.0	0.5	-0.6	0.9	-1.0	-1.2	-0.9	-1.4	0.9	1.4	1.1	-1.0	-0.1
Mn content in liver	0.3	0.4	1.3	0.6	-0.6	0.6	-0.1	0.1	0.3	0.2	-0.8	-0.4	-0.7	0.9	1.1
Na content in liver	0.2	0.2	0.7	0.2	-0.1	0.2	0.2	0.5	0.4	0.3	-0.6	-0.4	-0.5	0.7	0.9
Rb content in liver	1.3	1.6	3.0	1.2	-1.2	1.2	-1.6	-1.7	-1.5	-1.6	1.0	1.3	1.1	-1.0	-0.7
Se content in liver	0.3	0.4	0.9	0.6	-0.7	0.7	-0.9	-1.0	-0.6	-0.7	0.3	0.4	0.3	-0.3	-0.1
Sr content in liver	1.8	1.7	2.9	-0.8	0.5	-0.8	1.5	1.4	1.4	1.6	-1.3	-1.7	-1.5	1.5	0.8
Zn content in liver	1.4	1.6	3.6	-0.2	0.2	-0.0	1.5	1.3	1.5	1.2	-1.5	-1.2	-1.4	1.4	1.9
Bone: minimum diameter	1.4	2.6	7.8	2.8	-2.8	2.6	-1.5	-1.4	-1.6	-1.0	-0.8	-0.1	-0.6	0.6	0.3
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.1	0.3	-0.5	-0.5	-0.1	-0.0	0.2	0.2	-0.2	-0.0	-0.3	-0.5
Time in novel zone, hab. session 1	0.0	0.0	0.1	0.3	-0.2	0.3	-0.1	-0.2	-0.1	-0.3	0.1	0.3	0.2	0.0	0.2
Total zone transitions, hab. session 1	0.4	0.6	1.5	-0.6	0.6	-0.6	-0.3	-0.4	-0.5	-0.6	1.2	0.9	1.1	-1.0	-1.0
Total locomotion distance, hab. session 1	1.4	1.9	3.3	0.9	-0.5	0.5	-1.8	-1.5	-1.7	-1.5	1.6	1.5	1.6	-1.4	-1.3
Locomotion velocity, hab. session 1	1.2	1.7	2.8	0.7	-0.6	0.6	-1.5	-1.3	-1.7	-1.5	1.5	1.5	1.5	-1.3	-1.4
Time in familiar zone, hab. session 2	0.5	0.5	1.3	-0.3	0.4	-0.5	-0.6	-0.4	-0.7	-0.5	1.1	0.7	1.0	-1.0	-1.2
Time in novel zone, hab. session 2	0.2	0.2	0.7	-0.3	0.2	-0.2	0.5	0.5	0.8	0.4	-0.5	-0.4	-0.5	0.5	0.8
Total zone transitions, hab. session 2	1.4	1.9	4.0	-0.3	0.3	-0.1	-1.1	-1.2	-1.2	-1.5	2.0	1.9	2.0	-1.7	-1.1
Total locomotion distance, hab. session 2	2.2	3.0	4.8	1.0	-0.9	1.2	-2.1	-1.9	-2.0	-2.2	1.8	2.2	2.0	-1.6	-1.0
Locomotion velocity, hab. session 2	2.2	2.9	4.7	1.2	-1.2	1.4	-2.0	-1.9	-2.0	-2.2	1.6	2.1	1.9	-1.5	-1.0
Novel to familiar place preference ratio	1.0	1.0	2.6	1.5	-1.6	1.1	-1.6	-1.3	-0.8	-0.4	-0.4	-0.5	-0.7	0.4	-0.2
Novelty place preference	0.9	0.9	2.4	1.5	-1.5	1.1	-1.4	-1.2	-0.6	-0.2	-0.5	-0.6	-0.8	0.5	-0.1
Time in novel zone, NPP test	0.8	0.8	2.2	1.4	-1.4	1.0	-1.5	-1.2	-0.7	-0.4	-0.3	-0.4	-0.5	0.3	-0.2
Total zone transitions, NPP test	1.5	2.1	5.0	-0.3	0.4	-0.1	-1.0	-1.1	-1.2	-1.6	2.1	2.2	2.2	-1.9	-1.2
Total locomotion distance, NPP test	2.8	3.8	7.0	0.7	-0.5	0.8	-2.1	-2.0	-2.1	-2.4	2.3	2.7	2.6	-2.1	-1.4
Locomotion velocity, NPP test	2.3	3.2	5.3	0.8	-0.7	0.9	-2.0	-1.9	-2.0	-2.2	2.0	2.3	2.2	-1.9	-1.4
Intraocular pressure	0.5	0.8	1.4	0.5	-0.9	0.7	-1.0	-1.2	-1.2	-1.0	0.7	0.8	0.8	-0.6	-0.8
Delta distance traveled before/after self-admin	1.3	1.4	3.5	0.3	0.4	-0.2	-1.2	-1.1	-0.5	-1.1	1.6	1.5	1.4	-1.9	-1.3
Delta ambulatory time before/after self-admin	0.8	0.9	2.9	-0.2	0.9	-0.7	-0.7	-0.6	0.1	-0.6	1.4	1.2	1.1	-1.7	-0.9
Parametrial fat weight	0.7	1.3	4.7	1.7	-2.2	2.1	-0.8	-1.0	-1.0	-0.8	-0.6	0.1	-0.3	-0.1	-0.4
Pavlov. Cond. lever latency	3.1	4.0	8.1	-0.7	0.8	-0.8	-1.5	-1.5	-1.6	-1.8	2.9	2.3	2.7	-2.7	-2.8
Pavlov. Cond. magazine entry latency	1.2	1.5	3.1	1.5	-1.5	1.3	0.3	0.3	-0.0	0.7	-1.8	-1.4	-1.7	1.4	0.9
Pavlov. Cond. change in total contacts	0.6	0.6	1.8	0.3	-0.2	-0.1	0.4	0.4	0.5	1.0	-1.0	-1.3	-1.3	1.1	0.6
Pavlov. Cond. index score	1.8	2.3	4.5	1.9	-1.9	1.9	0.1	0.2	0.1	0.5	-2.1	-1.4	-1.9	1.8	1.7
Pavlov. Cond. latency score	2.3	2.9	6.3	1.6	-1.6	1.6	0.6	0.7	0.6	1.0	-2.5	-1.8	-2.3	2.3	2.2
Pavlov. Cond. lever contacts	1.5	1.7	3.9	0.9	-0.8	0.9	0.7	0.8	0.8	0.9	-1.9	-1.4	-1.7	1.8	2.0
Pavlov. Cond. magazine entry number	1.6	1.9	4.4	-1.2	1.2	-1.0	-0.8	-0.7	-0.4	-1.2	2.1	1.9	2.1	-1.8	-1.1
Pavlov. Cond. intertrial magazine entries	1.0	1.2	2.0	0.3	-0.7	0.7	-1.1	-1.4	-1.2	-1.4	1.1	1.3	1.3	-1.1	-1.1
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.0	4.0	2.0	-2.0	1.9	-0.1	0.0	-0.1	0.4	-1.9	-1.3	-1.8	1.6	1.4
Pavlov. Cond. response bias	1.6	2.0	4.5	1.3	-1.3	1.1	0.7	0.6	0.5	1.0	-2.1	-1.8	-2.1	1.8	1.4
Pavlov. Cond. lever latency	2.7	3.6	5.0	-1.3	1.2	-1.1	2.1	2.2	2.2	2.1	-1.8	-2.0	-1.9	2.1	2.1
Pavlov. Cond. magazine entry latency	2.0	2.3	5.4	-1.0	1.2	-1.2	-0.9	-0.8	-0.7	-1.1	2.3	1.7	2.0	-2.2	-1.8
Pavlov. Cond. change in total contacts	2.1	2.9	6.1	-0.1	0.1	-0.2	-1.4	-1.6	-1.7	-1.6	2.3	1.9	2.2	-2.4	-2.5
Pavlov. Cond. index score	2.5	3.2	6.4	0.2	-0.0	-0.1	-1.7	-1.7	-1.7	-1.7	2.4	1.9	2.2	-2.5	-2.5
Pavlov. Cond. latency score	2.6	3.2	6.1	0.2	-0.1	0.0	-1.7	-1.8	-1.8	-1.8	2.3	2.0	2.2	-2.5	-2.4
Pavlov. Cond. lever contacts	3.1	4.2	5.7	1.5	-1.4	1.4	-2.4	-2.4	-2.4	-2.3	1.9	2.1	2.0	-2.3	-2.2
Pavlov. Cond. magazine entry number	2.4	2.9	6.5	0.6	-0.8	0.9	1.4	1.2	1.1	1.4	-2.5	-1.9	-2.2	2.5	2.1
Pavlov. Cond. intertrial magazine entries	0.8	1.0	3.1	1.8	-1.6	1.7	-1.2	-1.0	-0.9	-0.7	-0.4	0.2	-0.1	0.1	0.2
Pavlov. Cond. lever-magazine prob. diff.	2.6	3.3	6.8	0.0	0.1	-0.3	-1.7	-1.6	-1.7	-1.7	2.4	2.0	2.2	-2.6	-2.6
Pavlov. Cond. response bias	2.4	3.2	5.4	0.7	-0.5	0.5	-2.0	-2.0	-1.9	-1.9	2.1	2.0	2.1	-2.3	-2.2
Time in closed arm before self-admin	0.8	0.9	2.6	-1.6	1.0	-1.1	1.2	0.8	0.7	0.9	-0.4	-0.9	-0.5	0.8	-0.4
Time in closed arm after self-admin	3.4	3.5	5.5	-1.9	1.3	-1.4	2.2	2.1	2.3	2.1	-1.8	-2.1	-1.9	1.8	1.2
Time in open arm before self-admin	0.3	0.4	2.3	0.7	-0.3	0.5	0.1	0.5	0.6	0.2	-0.7	-0.1	-0.5	0.0	1.5
Time in open arm after self-admin	0.4	0.5	0.9	0.4	-0.1	0.2	-0.6	-0.7	-0.7	-0.7	0.9	1.0	0.9	-1.0	-0.3
Bone: periosteal estimation	1.0	2.1	5.6	2.1	-2.4	2.3	-1.4	-1.5	-1.7	-1.3	-0.2	0.5	0.2	-0.0	-0.3
Bone: periosteal perimeter	1.6	2.7	5.6	2.2	-2.4	2.2	0.1	0.1	-0.2	0.4	-2.3	-1.5	-1.9	1.9	1.4
Bone: post-yield work	0.3	0.4	0.8	0.1	-0.1	0.2	-0.5	-0.5	-0.6	-0.7	0.7	0.9	0.9	-0.7	-0.5
Progressive ratio test 1 active lever presses	0.7	0.7	1.7	1.1	-1.3	1.3	-1.0	-0.8	-0.8	-0.9	0.0	0.4	0.2	-0.3	-0.4
Progressive ratio test 1 breakpoint	0.8	0.8	2.0	1.2	-1.4	1.4	-1.1	-0.9	-0.9	-1.0	0.0	0.5	0.2	-0.4	-0.6
Progressive ratio test 1 inactive lever presses	2.3	2.6	5.2	2.3	-2.1	2.1	-1.9	-1.8	-2.0	-1.6	0.4	1.0	0.6	-0.9	-1.0
Progressive ratio test 2 active lever presses	0.2	0.2	0.7	0.8	-0.7	0.7	-0.5	-0.3	-0.2	-0.1	-0.4	-0.1	-0.4	0.0	0.1
Progressive ratio test 2 breakpoint	0.3	0.3	0.9	0.9	-0.8	0.9	-0.6	-0.6	-0.5	-0.4	-0.2	0.2	-0.1	-0.2	-0.0
Progressive ratio test 2 inactive lever presses	0.3	0.3	1.1	1.0	-0.9	0.7	-0.5	-0.4	-0.4	-0.0	-0.5	-0.2	-0.4	0.5	0.1
Incentive Sensitization - Responses	0.1	0.1	0.2	0.2	-0.3	0.3	0.1	0.1	0.1	0.1	-0.4	-0.2	-0.3	-0.2	-0.4
Incentive Sensitization - Breakpoint	0.1	0.1	0.2	0.2	-0.2	0.3	0.1	0.1	0.1	0.2	-0.4	-0.3	-0.4	-0.1	-0.3
Sum of active levers in priming session hrs 5-6	0.8	0.8	2.8	0.7	-0.5	0.1	-1.1	-0.7	-1.5	-0.7	1.0	0.3	0.7	-0.3	-1.7
Progressive ratio	0.1	0.2	0.6	-0.6	0.6	-0.8	0.4	0.2	0.4	0.4	0.2	-0.1	0.1	0.2	0.4
Food seeking constrained by brief footshock	0.1	0.2	0.5	-0.3	0.5	-0.7	0.0	0.1	0.5	0.6	-0.0	-0.5	-0.4	0.4	0.2
Seeking ratio, punishment vs. effort	0.1	0.2	0.4	0.3	-0.3	0.4	-0.5	-0.4	-0.4	-0.4	0.2	0.3	0.3	-0.4	-0.7
Retroperitoneal fat weight	3.0	9.7	21.9	4.7	-4.5	4.6	-3.5	-3.6	-3.6	-3.0	0.3	1.5	0.6	-1.3	-1.4
Reaction time number correct	5.8	8.4	14.7	1.1	-0.8	1.1	-2.8	-3.1	-2.7	-3.4	3.5	3.8	3.6	-3.8	-2.5
Reaction time mean minus median	0.7	0.9	1.4	-0.6	0.3	-0.4	1.1	1.1	1.0	1.1	-1.2	-1.2	-1.2	1.2	0.8
Reaction time mean minus median AUC	0.4	0.5	1.3	0.2	-0.2	0.3	0.6	0.6	0.6	0.6	-1.1	-0.7	-0.9	0.9	1.1
Reaction time num false alarms	0.2	0.3	0.8	-0.9	0.6	-0.7	0.8	0.6	0.2	0.2	0.3	-0.0	0.3	-0.3	-0.6
Reaction time num false alarms AUC	0.3	0.5	1.5	-1.2	0.9	-1.0	1.0	0.8	0.4	0.3	0.4	0.1	0.4	-0.3	-0.4
Reaction time trials correct on left	5.8	8.4	14.7	1.1	-0.8	1.1	-2.8	-3.1	-2.7	-3.4	3.5	3.8	3.6	-3.8	-2.5
Reaction time trials on left	6.0	8.6	15.1	1.1	-0.9	1.1	-2.9	-3.1	-2.8	-3.5	3.5	3.9	3.7	-3.9	-2.5
Reaction time mean	0.4	0.5	1.3	0.4	-0.8	0.6	-0.5	-0.9	-0.9	-0.8	0.5	0.6	0.5	-0.8	-1.2
Reaction time mean AUC	0.7	0.9	1.6	0.5	-0.8	0.8	-0.8	-1.1	-1.1	-1.1	0.7	0.9	0.9	-1.1	-1.3
Median of all reaction times	0.8	1.0	2.4	0.4	-0.9	0.7	-0.8	-1.2	-1.1	-1.2	0.9	1.0	0.9	-1.2	-1.5
Reaction time omissions	0.4	0.5	0.8	0.7	-0.9	0.8	-0.6	-0.7	-0.9	-0.8	0.4	0.7	0.6	-0.5	-0.5
Reaction time false alarm rate	2.0	2.8	5.1	-1.7	1.2	-1.5	2.3	2.2	1.7	1.9	-1.4	-1.8	-1.4	1.7	0.9
Reaction time premature initiation rate	0.6	0.8	2.9	-1.6	1.4	-1.7	0.9	0.7	0.6	0.7	0.5	-0.2	0.3	0.1	-0.5
Reaction time premature initiations	1.7	2.4	5.6	-0.8	0.8	-0.9	-0.9	-1.1	-0.9	-1.3	2.4	1.9	2.2	-2.1	-1.8
Std. dev. reaction times	0.1	0.2	0.8	-0.9	0.5	-0.6	0.5	0.3	0.3	0.1	0.3	0.1	0.2	-0.3	-0.5
Reaction time trials completed	6.0	8.6	15.1	1.1	-0.9	1.1	-2.9	-3.1	-2.8	-3.5	3.5	3.9	3.7	-3.9	-2.5
Reaction time trials AUC	6.1	8.7	15.2	1.2	-0.9	1.2	-2.9	-3.2	-2.8	-3.5	3.5	3.9	3.7	-3.9	-2.5
Run reversals in cocaine runway, females	1.3	1.2	2.6	-1.0	0.8	-0.8	-0.2	-0.3	-0.5	-0.8	1.6	1.3	1.5	-1.5	-1.6
Run reversals in cocaine runway, males	1.0	1.0	3.3	0.5	-0.9	0.7	0.3	0.0	0.1	0.6	-1.4	-1.2	-1.3	1.8	1.2
Latency to leave start box in cocaine runway	0.2	0.3	0.9	-0.6	0.5	-0.5	0.2	0.3	0.2	-0.0	0.4	0.3	0.4	-0.9	-0.9
Latency to leave start box in cocaine runway, F	0.4	0.4	1.5	-0.2	0.3	-0.1	-0.2	-0.1	-0.2	-0.6	0.8	0.9	0.8	-1.2	-0.8
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	-0.4	0.3	-0.2	0.2	0.3	0.3	0.3	-0.3	-0.4	-0.4	-0.2	-0.2
Std. dev. time between licks in bursts	3.6	4.3	6.6	1.3	-1.1	1.4	-2.4	-2.1	-2.3	-2.5	2.0	2.6	2.4	-2.3	-1.8
Total sessions with >9 infusions	0.2	0.2	0.6	-0.6	0.3	-0.4	0.4	0.5	0.8	0.4	-0.4	-0.2	-0.3	0.4	0.6
Short access day 1 total inactive lever presses	0.2	0.2	0.7	0.8	-0.5	0.7	-0.3	0.0	-0.2	-0.4	-0.1	0.6	0.3	-0.2	0.3
Short access day 10 total inactive lever presses	1.5	1.7	4.9	2.2	-1.9	1.9	-1.4	-1.6	-1.5	-0.8	-0.3	0.1	-0.3	-0.1	-0.1
Short access day 1 total infusions	0.7	0.8	1.6	-1.2	1.2	-1.3	0.9	1.0	1.1	0.9	-0.1	-0.4	-0.2	0.4	0.6
Short access day 10 total infusions	0.2	0.3	0.9	1.0	-0.7	0.8	-0.6	-0.4	-0.4	-0.1	-0.4	-0.2	-0.4	0.3	0.2
Short access total infusions	0.0	0.0	0.1	-0.0	0.0	-0.0	-0.1	0.2	0.2	0.1	-0.2	-0.1	-0.2	0.2	0.1
Short access day 1 locomotion	0.9	1.0	1.8	-0.5	0.8	-0.6	1.0	1.1	1.1	1.2	-1.1	-1.0	-1.1	1.0	1.3
Short access day 10 total locomotion	0.8	0.9	1.6	-0.5	0.4	-0.5	0.9	1.0	1.0	1.2	-1.1	-1.3	-1.2	1.2	1.0
Short access total locomotion	1.4	1.4	2.1	-0.8	0.8	-0.7	1.2	1.3	1.4	1.4	-1.2	-1.3	-1.2	1.2	1.5
One hour access (0.3 mA shock)	1.0	1.2	2.3	1.5	-1.4	1.4	-1.5	-1.4	-1.1	-1.2	0.4	0.8	0.5	-0.6	-0.6
Compulsive drug intake	0.8	0.8	1.5	0.8	-0.9	0.8	-1.0	-0.9	-1.0	-1.0	0.7	0.8	0.8	-0.8	-1.2
One hour access (shock baseline)	0.2	0.3	1.0	0.8	-0.5	0.9	-0.4	-0.2	-0.2	-0.2	-0.4	0.2	-0.2	0.2	1.0
Social response proportion	0.2	0.3	0.7	-0.3	0.5	-0.5	-0.2	-0.5	-0.1	-0.3	0.8	0.7	0.7	-0.7	-0.2
Social responses	0.1	0.1	0.3	0.1	0.1	0.0	-0.4	-0.6	-0.2	-0.4	0.5	0.5	0.4	-0.4	0.3
Social time	0.2	0.3	0.6	-0.0	0.3	-0.2	-0.7	-0.7	-0.4	-0.5	0.8	0.6	0.6	-0.8	-0.1
Soleus weight	0.6	1.8	6.2	2.2	-2.3	2.5	-0.7	-1.2	-1.2	-1.0	-0.7	0.3	-0.2	0.4	0.4
Bone: stiffness	0.3	0.5	1.7	0.9	-1.3	1.3	-0.2	-0.6	-0.9	-0.6	-0.3	0.3	0.1	0.3	-0.1
Tibialis anterior weight	0.1	0.3	0.5	-0.5	-0.3	0.4	0.1	-0.7	-0.6	-0.7	0.4	0.7	0.7	-0.1	-0.1
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.3	0.3	-0.2	0.4	-0.0	-0.3	-0.2	-0.2	-0.1	0.2	0.1	0.2	0.6
Time to tail flick, vehicle, after self-admin	1.5	1.6	3.0	-1.6	1.7	-1.4	1.6	1.7	1.6	1.2	-0.5	-0.6	-0.5	0.6	1.0
Time to tail flick, test, before self-admin	0.2	0.2	0.5	-0.1	-0.0	-0.1	0.4	0.2	0.3	0.5	-0.6	-0.6	-0.6	0.7	0.3
Time to tail flick, test, after self-admin	0.2	0.2	1.0	0.0	0.1	-0.3	0.2	0.3	0.7	0.5	-0.3	-0.3	-0.4	0.6	1.0
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.5	-0.0	0.3	-0.2	-0.2	0.1	0.1	-0.2	0.4	0.5	0.4	-0.7	-0.2
Delta time to tail flick, test, before/after SA	0.3	0.2	0.6	-0.6	0.6	-0.8	0.3	0.5	0.7	0.5	-0.0	-0.4	-0.3	0.2	0.3
Tibia length	3.3	9.2	27.5	5.0	-5.2	4.9	-1.1	-0.9	-1.2	-0.3	-3.5	-1.8	-2.9	2.2	1.2
Ambulatory time before self-admin	0.9	0.9	2.8	1.4	-1.7	1.4	-1.0	-0.9	-1.4	-0.6	-0.3	-0.2	-0.3	0.7	-0.1
Ambulatory time after self-admin	1.0	1.1	2.3	1.1	-0.8	0.7	-1.5	-1.3	-1.1	-1.2	1.0	1.0	0.8	-0.9	-0.9
Bone: tissue strength	1.6	1.6	3.5	1.7	-1.4	1.5	-1.9	-1.5	-1.3	-1.4	0.6	1.0	0.7	-0.9	-0.6
Total heroin consumption	0.1	0.1	0.4	0.6	-0.3	-0.1	-0.4	-0.1	-0.3	0.2	-0.0	-0.5	-0.3	0.5	-0.2
Bone: trabecular number	0.0	0.1	0.4	-0.4	-0.1	0.1	0.6	-0.2	0.2	0.1	-0.2	-0.1	-0.1	0.2	-0.0
Bone: trabecular spacing	4.0	5.2	8.1	1.3	-0.7	1.0	-2.8	-2.3	-2.5	-2.6	2.6	2.8	2.6	-2.7	-1.9
Bone: trabecular thickness	1.2	1.4	3.2	-0.0	-0.4	0.0	1.2	0.9	0.9	1.3	-1.7	-1.8	-1.7	1.6	0.7
Bone: trabecular tissue density	0.5	0.6	1.5	-1.1	1.2	-1.1	1.0	1.2	0.8	0.7	-0.1	-0.2	-0.1	0.2	0.3
Water consumed over 24 hours	0.6	0.8	1.6	0.3	0.3	-0.3	0.0	0.8	1.1	1.0	-1.0	-1.1	-1.2	1.1	1.3
Number of responses in last shaping day	0.9	0.9	2.8	1.6	-1.6	1.7	-0.7	-0.8	-0.9	-0.6	-0.6	0.2	-0.1	0.2	0.4