Hub : Genes

Ndufaf8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ndufaf8 0.04 0.03 8.0e-05 0.05 0.04 0.03 0.04 2.8e-05 5.9e-05 7.3e-04 4.5e-05
2 NAcc mRNA stability Ndufaf8 0.23 0.13 4.4e-04 -0 0 0.02 -0 5.3e-01 1.0e-01 7.1e-04 5.8e-01
3 BLA gene expression Ndufaf8 0.14 0.09 1.7e-05 0.1 0.07 0.05 0.06 7.2e-06 8.6e-05 9.1e-04 2.7e-04
4 OFC mRNA stability Ndufaf8 0.23 0.14 1.1e-03 0.05 0.03 0.06 0.08 2.5e-02 5.3e-02 1.9e-02 6.3e-03
5 Adipose gene expression Ndufaf8 0.07 0.05 8.5e-06 0.02 0.04 0.05 0.05 1.3e-03 1.3e-05 3.3e-06 7.6e-06
6 pVTA gene expression Ndufaf8 0.1 0.06 1.4e-04 0.06 0.05 0.06 0.06 1.2e-05 9.6e-05 3.2e-05 2.5e-05
7 Liver mRNA stability Ndufaf8 0.31 0.14 0.0e+00 0.22 0.23 0.22 0.22 1.6e-23 6.3e-25 2.6e-24 1.7e-23
8 Liver gene expression Ndufaf8 0.1 0.07 6.1e-08 0.03 0.06 0.06 0.06 3.3e-04 1.5e-07 2.0e-07 3.5e-07
9 Brain gene expression Ndufaf8 0.16 0.08 3.4e-09 0.08 0.1 0.09 0.09 3.0e-08 1.9e-09 2.1e-08 5.5e-09
10 NAcc gene expression Ndufaf8 0.13 0.06 2.0e-12 0.04 0.07 0.07 0.07 6.9e-07 3.2e-11 1.0e-10 3.5e-11
11 PL gene expression Ndufaf8 0.12 0.07 1.0e-05 0.04 0.05 0.05 0.04 2.6e-05 5.7e-06 7.9e-06 1.4e-05
12 IL gene expression Ndufaf8 0.25 0.16 3.4e-03 0.04 0.1 0.14 0.09 3.9e-02 2.5e-03 2.7e-04 3.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.64.00.5-2.00.70.30.40.7-0.70.50.30.50.5-0.2
Area under the delay curve0.40.52.1-1.4-0.1-0.7-1.1-0.6-0.60.60.00.40.50.40.2
BMI with tail0.93.25.91.5-2.42.41.71.12.2-1.91.51.31.51.71.5
BMI without tail1.85.510.43.1-3.23.02.51.63.2-2.71.81.01.31.41.6
Body weight0.94.015.84.0-2.62.81.90.82.9-2.00.7-0.5-0.10.00.5
Weight adjusted by age0.91.36.42.5-0.91.21.50.71.7-1.10.4-0.4-0.2-0.10.2
Bone surface0.20.41.40.5-0.1-0.3-0.6-0.6-0.30.3-0.5-0.9-0.8-0.9-1.2
Bone volume0.10.21.10.7-1.10.3-0.0-0.10.3-0.3-0.0-0.3-0.1-0.1-0.6
Breakpoint value in progressive ratio session0.30.41.10.6-0.60.71.10.70.8-0.3-0.20.40.00.80.7
Number of licking bursts0.10.10.40.30.50.1-0.10.20.1-0.40.3-0.1-0.0-0.4-0.6
Context. condit. distance diff. score3.23.95.51.0-1.52.42.22.22.2-2.32.21.92.12.01.0
Locomotion velocity, session 13.13.36.3-2.00.9-2.5-2.3-2.1-2.22.3-1.8-1.2-1.3-1.2-1.1
Locomotion distance, session 10.60.83.2-1.80.3-0.6-0.30.7-0.40.00.81.21.20.90.6
Locomotion velocity, session 23.03.57.3-2.72.5-2.5-2.3-1.4-2.52.0-1.2-0.6-0.7-0.9-1.2
Locomotion distance, session 20.40.51.1-0.60.30.20.41.00.2-0.51.01.01.00.80.4
Locomotion velocity, session 31.31.54.1-1.62.0-1.6-1.1-1.0-1.51.5-1.0-0.5-0.7-0.6-0.4
Locomotion distance, session 30.90.94.4-2.11.1-1.2-1.1-0.4-1.21.0-0.30.50.30.30.2
Stereotopy head waving bouts, day 31.01.24.8-0.92.2-1.3-0.7-0.7-1.31.1-0.9-0.6-0.8-0.9-0.8
Stereotopy head waving duration, day 30.70.85.6-0.82.4-0.9-0.1-0.1-0.90.7-0.4-0.2-0.4-0.5-0.8
Locomotion velocity, session 70.20.20.6-0.80.5-0.10.00.3-0.20.00.30.60.50.60.1
Locomotion distance, session 71.72.25.4-1.7-0.70.60.51.50.3-0.91.72.32.22.11.1
Stereotopy head waving bouts, day 70.10.10.30.50.40.30.60.20.5-0.30.10.10.10.2-0.2
Stereotopy head waving duration, day 70.60.75.40.62.3-0.10.60.10.0-0.0-0.2-0.6-0.5-0.7-0.9
Locomotion velocity, session 80.91.12.2-0.60.60.70.91.40.6-0.91.41.51.51.20.5
Locomotion distance, session 84.76.810.30.6-1.52.82.73.22.5-2.93.22.93.02.81.8
Degree of sensitization distance1.71.73.00.9-0.81.71.71.61.4-1.61.41.21.21.10.7
Degree of sensitization stereotypy0.50.51.10.7-0.10.81.00.71.0-0.80.60.50.60.70.3
Conditioned locomotion3.03.57.52.5-1.32.42.71.92.3-2.31.60.81.01.01.3
Cocaine response after cond. corrected0.20.32.0-0.4-0.7-0.00.0-0.40.10.3-0.30.30.10.61.4
Cocaine response after cond. not corrected0.20.30.9-0.90.1-0.6-0.4-0.6-0.50.7-0.40.10.00.30.7
Cocaine response before conditioning0.40.51.8-1.01.2-0.7-0.60.0-0.80.40.1-0.00.1-0.4-1.3
Saline control response0.81.14.12.0-1.61.40.90.41.4-1.20.5-0.4-0.1-0.2-0.2
Bone: connectivity density0.10.20.6-0.00.10.20.00.60.0-0.50.60.30.40.1-0.8
Bone: cortical apparent density0.70.94.5-2.11.2-1.2-0.5-0.3-1.10.9-0.20.60.40.50.5
Bone: cortical area1.21.810.23.2-0.21.21.4-0.21.4-0.8-0.5-1.5-1.2-1.1-0.7
Bone: cortical porosity1.61.73.90.60.1-0.9-1.0-1.7-0.81.4-2.0-1.8-1.9-1.4-0.1
Bone: cortical porosity1.01.12.61.0-0.2-0.4-0.5-1.4-0.31.0-1.6-1.5-1.6-1.10.1
Bone: cortical thickness1.11.88.22.90.80.61.4-0.60.8-0.2-1.0-1.8-1.7-1.5-0.4
Bone: cortical thickness0.40.51.61.3-0.90.70.90.10.9-0.4-0.1-0.3-0.30.00.8
Bone: cortical tissue density0.81.05.0-2.21.2-1.4-0.6-0.4-1.21.0-0.30.60.30.40.5
Condit. Reinf. active minus inactive responses1.11.23.11.8-0.71.61.50.81.6-1.30.70.20.40.50.2
Condit. Reinf. active-inactive response ratio0.91.01.71.2-1.11.31.30.71.3-1.10.60.50.50.80.8
Condit. Reinf. active responses1.51.96.22.5-0.82.01.81.02.0-1.60.90.10.30.3-0.0
Condit. Reinf. inactive responses0.30.41.41.2-0.00.80.80.50.9-0.70.4-0.10.1-0.0-0.3
Incentive salience index mean0.70.92.91.7-0.01.31.40.81.4-1.10.60.00.20.1-0.2
Condit. Reinf. lever presses0.30.51.30.31.10.61.01.00.6-0.70.80.50.50.3-0.2
Condit. Reinf. active minus inactive responses0.30.51.30.81.00.71.10.90.6-0.60.50.10.1-0.10.4
Condit. Reinf. active-inactive response ratio0.60.72.21.41.50.20.7-0.00.3-0.1-0.5-1.0-1.0-1.0-0.4
Condit. Reinf. active responses0.81.12.00.20.21.11.41.40.9-1.01.01.11.01.01.3
Condit. Reinf. inactive responses1.11.52.9-0.9-0.90.80.81.20.6-0.71.21.71.51.71.7
Condit. Reinf. lever presses2.33.24.40.6-2.12.01.72.01.8-1.71.71.91.82.01.8
Condit. Reinf. lever reinforcers received1.82.63.80.3-0.71.71.91.91.5-1.51.61.81.61.81.9
Conditioned reinforcement - actives0.10.10.30.00.60.50.40.5-0.0-0.30.40.30.20.0-0.0
Conditioned reinforcement - inactives0.30.41.81.30.40.90.70.40.9-0.50.2-0.1-0.10.00.1
Conditioned locomotion0.70.96.00.52.50.81.10.90.5-0.50.50.40.2-0.00.8
Patch foraging indifference point 0 sec0.20.51.00.3-0.71.01.00.80.7-0.50.40.60.40.60.7
Patch foraging indifference point AUC0.10.20.50.1-0.50.30.40.60.2-0.30.40.40.30.30.7
Delay disc. indifference point, 0s delay0.10.10.20.3-0.10.50.30.40.4-0.30.30.10.20.10.2
Delay disc. indifference point, 16s delay1.11.32.7-0.8-1.60.4-0.10.90.4-0.71.31.61.61.51.0
Delay disc. indifference point, 2s delay0.30.30.9-0.51.0-0.7-0.7-0.7-0.30.6-0.4-0.1-0.2-0.1-0.6
Delay disc. indifference point, 24s delay2.22.56.3-2.50.7-2.1-2.5-1.8-1.91.9-1.1-0.3-0.3-0.3-0.4
Delay disc. indifference point, 4s delay0.20.20.9-1.00.7-0.5-0.5-0.2-0.70.6-0.4-0.0-0.2-0.2-0.0
Delay disc. indifference point, 8s delay0.81.02.4-1.20.3-1.1-1.5-1.5-1.01.2-0.9-0.6-0.4-0.4-0.5
Indifference point function ln k0.10.21.1-1.0-0.1-0.0-0.30.1-0.20.00.30.80.70.80.1
Indifference point function log k0.10.21.1-1.0-0.1-0.0-0.30.1-0.20.00.30.80.70.80.1
Patch foraging total patch changes 0 sec0.51.01.90.4-1.11.31.41.21.0-0.90.70.90.81.11.1
Patch foraging total patch changes 12 sec0.10.10.30.0-0.30.10.50.50.10.1-0.3-0.1-0.2-0.00.5
Patch foraging total patch changes 18 sec1.52.25.70.1-2.41.11.41.91.0-1.21.41.71.61.71.3
Patch foraging total patch changes 24 sec0.71.32.81.3-1.71.41.41.11.4-1.10.80.50.50.60.9
Patch foraging total patch changes 6 sec0.10.20.50.70.20.10.3-0.10.10.2-0.5-0.7-0.7-0.7-0.3
Patch foraging time to switch 0 sec0.30.72.0-0.9-0.0-1.3-1.4-1.0-0.90.8-0.6-0.4-0.3-0.3-0.6
Patch foraging water rate 0 sec2.04.29.02.2-0.72.93.02.42.6-2.21.71.31.21.41.4
Patch foraging water rate 12 sec1.73.66.00.7-0.82.32.52.31.8-2.02.02.11.92.01.7
Patch foraging water rate 18 sec1.82.85.21.30.42.12.32.31.8-2.01.81.51.31.20.9
Patch foraging water rate 24 sec7.19.916.32.2-2.13.94.03.53.5-3.43.12.92.83.02.6
Patch foraging water rate 6 sec0.81.12.90.50.51.31.41.70.9-1.21.11.10.90.80.4
Seeking ratio, delayed vs. immediate footshock0.70.85.21.2-2.30.50.4-0.10.9-0.50.1-0.5-0.1-0.3-1.1
Distance traveled before self-admin0.40.51.81.4-1.00.80.80.41.2-0.5-0.1-0.1-0.10.30.2
Distance traveled after self-admin1.92.43.51.3-1.91.71.91.61.7-1.71.41.41.31.41.2
Extensor digitorum longus weight1.14.35.60.6-2.32.31.82.02.2-2.32.32.22.32.41.4
Bone: elastic displacement0.30.41.51.20.50.51.10.20.5-0.3-0.2-0.3-0.5-0.30.6
Bone: elastic work1.41.88.02.8-0.30.51.0-0.90.80.1-1.4-1.9-1.9-1.40.3
Bone: endosteal estimation0.51.25.70.2-2.40.9-0.00.81.0-1.01.11.01.21.10.6
Bone: endosteal perimeter0.40.83.41.4-1.80.2-0.7-0.80.4-0.1-0.4-1.1-0.7-0.7-0.8
Epididymis fat weight1.34.48.32.4-2.82.92.41.82.6-2.41.71.21.31.51.3
Delta time in closed arm before/after self-admin0.70.65.50.22.3-0.10.00.8-0.4-0.20.4-0.2-0.2-0.8-0.6
Delta time in open arm before/after self-admin0.40.41.40.2-1.20.70.50.40.7-0.50.50.60.70.70.5
Diff in mean of infusions in LGA sessions0.00.10.20.30.3-0.10.1-0.10.30.2-0.4-0.3-0.3-0.10.0
Delay discount exponential model param0.80.93.41.8-0.11.11.50.91.1-1.00.4-0.2-0.2-0.20.0
Extinction: sum of active levers before priming0.20.21.7-0.71.3-0.4-0.1-0.1-0.50.3-0.20.30.00.20.0
Active lever presses in extinction session 60.50.51.5-0.61.2-0.7-0.3-0.4-0.51.2-1.2-0.4-0.8-0.20.1
Bone: final force1.42.310.93.3-1.51.91.80.42.1-1.40.2-0.8-0.5-0.3-0.2
Bone: final moment1.62.612.53.5-1.72.01.90.32.1-1.3-0.0-1.0-0.7-0.4-0.0
Food consumed during 24 hour testing period1.01.45.20.92.31.01.71.20.9-0.90.60.60.40.51.4
Glucose6.610.318.3-3.72.9-4.1-3.5-3.5-4.04.3-3.5-1.8-2.4-1.7-1.2
Heart weight0.20.30.90.9-0.90.70.5-0.10.9-0.3-0.1-0.1-0.10.10.7
Delay discount hyperbolic model param0.70.83.11.8-0.21.11.50.91.0-1.00.4-0.1-0.1-0.20.0
Intermittent access intake day 1-15 change0.20.43.20.4-1.8-0.1-0.1-0.70.20.2-0.7-0.4-0.50.0-0.3
Intermittent access intake escalation0.20.42.80.4-1.7-0.1-0.1-0.60.20.2-0.6-0.4-0.40.0-0.3
Intermittent access intake escalation 20.50.62.41.0-1.6-0.0-0.1-0.70.40.3-1.0-0.9-0.9-0.2-0.7
Intermitt. access day 1 inactive lever presses0.83.05.92.1-1.02.32.21.72.4-2.01.41.01.11.31.4
Intermitt. access day 15 inactive lever presses1.02.14.81.7-0.52.21.91.61.8-1.71.41.11.01.10.1
Intermitt. access escalation Index0.40.61.10.8-0.50.90.90.81.0-1.00.90.40.60.30.5
Intermittent access day 1 total infusions0.10.10.30.3-0.30.30.60.30.2-0.30.20.20.10.10.2
Intermittent access day 15 total infusions0.20.21.10.8-1.10.30.5-0.10.6-0.3-0.0-0.2-0.10.0-0.2
Intermittent access terminal intake (last 3 days)0.30.42.01.1-1.40.50.60.00.6-0.3-0.1-0.4-0.3-0.2-0.3
Intermittent access total infusions0.10.20.70.6-0.90.40.6-0.00.5-0.30.10.00.00.1-0.1
Intermittent access day 1 locomotion0.30.44.30.42.10.30.50.40.2-0.20.2-0.0-0.1-0.20.3
Intermittent access day 15 total locomotion0.10.20.70.70.90.40.70.10.3-0.1-0.2-0.3-0.5-0.40.3
Intermittent access total locomotion0.10.20.50.70.70.50.70.30.4-0.20.0-0.1-0.2-0.10.3
Intermittent access standard deviation0.30.71.6-0.71.3-0.9-0.5-0.7-0.81.1-1.2-0.5-0.8-0.4-0.5
Left kidney weight0.31.23.10.21.7-1.0-0.6-0.7-0.81.0-1.2-1.3-1.4-1.4-0.5
Right kidney weight0.21.14.50.02.1-1.0-0.5-0.5-0.90.8-1.0-1.1-1.2-1.4-0.5
Cocaine induced anxiety0.60.92.11.00.40.0-0.1-1.40.30.8-1.5-1.3-1.4-0.9-0.2
Post-drug Anxiety0.70.72.2-0.30.4-0.2-0.7-1.5-0.51.2-1.5-0.7-1.0-0.40.3
Baseline Anxiety0.70.83.4-1.80.7-0.9-1.0-0.5-1.40.8-0.30.40.20.20.3
Tail length0.72.916.44.0-0.41.61.80.62.0-1.50.0-1.5-1.1-1.3-0.7
Length with tail0.73.19.73.10.40.30.1-0.90.40.3-1.6-2.8-2.6-2.6-1.5
Length without tail0.72.45.81.10.7-0.6-1.0-1.5-0.91.5-2.1-2.2-2.4-2.1-1.0
Times rat made contact with spout1.21.49.70.83.1-0.00.8-0.2-0.20.5-1.0-1.0-1.3-1.10.6
Lifetime Intake0.00.00.20.3-0.10.20.5-0.00.2-0.20.10.10.00.1-0.1
Liver weight, left0.71.22.2-1.00.3-1.4-1.5-1.1-1.31.3-1.1-0.9-0.9-1.0-0.1
Liver weight, right0.81.47.62.80.81.01.20.61.1-0.90.1-1.1-0.9-1.1-0.9
Locomotor activity0.20.21.0-1.00.7-0.6-0.30.3-0.50.4-0.10.30.10.20.5
Locomotor testing distance0.30.51.0-1.00.3-0.20.10.9-0.1-0.10.71.00.90.80.8
Locomotor testing rearing0.71.33.1-0.31.10.91.51.80.6-0.81.21.51.11.11.2
Locomotion in novel chamber0.30.31.80.11.30.50.50.60.1-0.40.70.40.40.00.4
Locomotion in novel chamber post-restriction0.60.93.11.6-1.80.90.4-0.50.7-0.5-0.3-0.9-0.5-0.5-1.3
Fecal boli incidents, locomotor time 10.10.10.4-0.40.6-0.40.10.4-0.40.10.20.20.2-0.00.1
Change in fecal boli incidents, locomotor task2.32.34.5-1.6-0.5-1.9-2.1-1.8-1.81.9-1.7-0.8-1.0-0.6-1.3
Time >=10cm from walls, locomotor time 10.70.81.60.3-1.10.91.01.10.5-1.31.10.80.90.70.3
Bouts of movement, locomotor time 10.70.73.2-1.8-0.6-1.0-1.2-0.6-1.10.8-0.40.20.20.30.5
Total resting periods, locomotor time 11.11.24.4-2.10.2-1.4-1.5-1.0-1.51.3-0.8-0.1-0.2-0.10.2
Rest time, locomotor task time 11.01.32.3-1.00.2-1.5-1.4-1.3-1.21.4-1.3-1.0-1.1-0.9-0.6
Distance moved, locomotor task time 10.30.51.00.9-1.00.90.70.60.8-0.80.60.30.40.20.7
Vertical activity count, locomotor time 10.81.93.91.6-0.82.01.71.51.5-1.71.40.91.00.81.1
Time >=10cm from walls, locomotor time 20.71.03.4-0.21.9-0.9-0.4-0.5-1.00.6-0.6-1.0-0.9-1.3-1.4
Bouts of movement, locomotor time 20.20.41.8-1.40.0-0.7-0.8-0.6-0.60.30.10.50.50.50.3
Total resting periods, locomotor time 20.10.20.9-1.00.2-0.3-0.5-0.3-0.30.00.40.50.60.40.4
Rest time, locomotor task time 20.30.40.8-0.70.6-0.5-0.7-0.6-0.90.5-0.5-0.5-0.5-0.7-0.0
Distance moved, locomotor task time 20.10.10.30.5-0.60.0-0.00.20.2-0.00.1-0.3-0.2-0.3-0.3
Vertical activity count, locomotor time 20.40.51.50.7-0.40.70.81.20.8-0.80.90.60.60.50.2
Light reinforcement 11.33.28.01.70.32.22.82.22.0-2.32.01.31.41.00.7
Light reinforcement 20.91.34.22.00.61.51.81.01.3-1.50.9-0.00.2-0.2-0.5
Bone: marrow area0.61.25.60.2-2.40.90.00.81.0-1.01.11.01.21.20.6
Bone: maximum diameter0.51.03.31.8-0.10.2-0.2-0.70.3-0.1-0.6-1.5-1.2-1.4-1.3
Bone: maximum force1.32.311.13.3-1.51.91.80.42.1-1.50.3-0.8-0.4-0.3-0.0
Bone: maximum moment1.42.512.33.5-1.82.01.80.22.1-1.40.1-0.9-0.6-0.40.1
Mean time between licks in bursts0.20.52.4-1.50.9-1.0-0.9-0.3-0.80.7-0.10.20.20.10.2
Mean num. licks in bursts0.20.31.60.31.00.20.80.10.10.3-0.5-0.1-0.40.11.2
Cd content in liver2.12.44.2-0.6-0.31.11.51.81.1-1.31.72.01.91.91.9
Co content in liver0.10.10.80.10.90.20.30.10.10.1-0.2-0.2-0.2-0.20.1
Cu content in liver0.50.61.40.91.20.00.2-0.6-0.20.5-1.0-1.0-1.1-0.80.2
Fe content in liver0.60.73.0-0.50.40.20.80.90.4-0.50.81.00.90.91.7
K content in liver1.31.22.51.40.71.41.61.41.3-1.51.20.40.60.2-0.0
Mg content in liver1.61.63.30.70.41.51.51.81.3-1.71.81.11.30.80.3
Mn content in liver0.50.54.90.32.20.10.50.3-0.20.0-0.1-0.4-0.4-0.6-0.7
Na content in liver0.30.31.20.11.10.40.80.60.3-0.50.60.30.40.10.0
Rb content in liver2.52.94.91.7-0.92.22.12.02.0-2.01.71.21.31.21.2
Se content in liver0.70.81.80.7-0.61.21.31.01.0-1.00.80.70.70.80.9
Sr content in liver1.10.91.5-0.61.2-1.0-0.9-1.2-0.91.2-1.2-0.8-1.0-0.7-0.5
Zn content in liver0.50.51.71.31.10.70.60.20.5-0.50.1-0.6-0.4-0.7-0.9
Bone: minimum diameter0.71.37.92.8-0.31.31.2-0.01.4-0.8-0.3-1.0-0.8-0.6-0.1
Time in familiar zone, hab. session 10.10.10.2-0.30.3-0.00.30.0-0.00.2-0.20.20.10.40.3
Time in novel zone, hab. session 10.10.10.30.20.60.20.40.40.1-0.30.30.10.1-0.0-0.4
Total zone transitions, hab. session 10.50.71.4-0.5-0.90.40.40.80.6-0.60.91.21.11.20.9
Total locomotion distance, hab. session 11.62.33.40.5-0.81.61.81.71.7-1.51.51.61.61.71.5
Locomotion velocity, hab. session 11.52.22.80.6-1.51.51.51.51.7-1.51.51.51.51.61.6
Time in familiar zone, hab. session 20.70.81.7-0.5-1.00.50.60.70.7-0.50.81.11.11.31.2
Time in novel zone, hab. session 20.40.41.2-0.11.1-0.5-0.5-0.3-0.80.4-0.4-0.6-0.6-0.8-1.1
Total zone transitions, hab. session 21.82.23.9-0.1-0.51.21.31.91.3-1.62.01.92.01.71.2
Total locomotion distance, hab. session 22.43.15.30.9-0.31.92.12.31.9-2.12.21.71.91.60.9
Locomotion velocity, hab. session 22.33.04.71.2-0.72.02.02.22.0-2.22.11.51.81.50.9
Novel to familiar place preference ratio0.60.72.91.70.31.01.40.10.8-0.3-0.5-0.4-0.6-0.00.8
Novelty place preference0.50.62.61.60.30.91.2-0.00.6-0.2-0.6-0.5-0.7-0.20.7
Time in novel zone, NPP test0.50.62.21.50.31.01.30.20.7-0.4-0.4-0.3-0.50.00.7
Total zone transitions, NPP test1.72.44.8-0.3-1.01.11.22.01.2-1.62.22.02.11.71.0
Total locomotion distance, NPP test3.24.47.00.6-1.42.12.22.62.1-2.42.72.32.52.11.2
Locomotion velocity, NPP test2.63.75.40.8-1.62.02.02.32.0-2.22.32.02.11.91.2
Intraocular pressure1.01.45.61.1-2.41.30.90.71.4-1.10.80.70.91.10.9
Delta distance traveled before/after self-admin0.90.91.8-0.4-0.70.90.91.20.2-0.91.11.31.21.01.0
Delta ambulatory time before/after self-admin0.60.71.8-1.1-0.30.40.41.0-0.3-0.51.01.31.10.90.8
Parametrial fat weight0.30.71.81.4-0.81.00.90.51.1-1.10.70.20.30.21.1
Pavlov. Cond. lever latency3.94.99.3-0.8-2.51.61.42.21.6-1.72.32.92.83.02.5
Pavlov. Cond. magazine entry latency0.91.12.71.4-0.3-0.2-0.5-1.40.10.6-1.3-1.6-1.6-1.4-0.4
Pavlov. Cond. change in total contacts0.70.71.80.10.6-0.6-0.5-1.2-0.51.0-1.3-1.0-1.2-0.8-0.2
Pavlov. Cond. index score1.51.94.51.80.8-0.2-0.3-1.3-0.10.5-1.4-2.1-2.0-2.0-1.3
Pavlov. Cond. latency score2.32.96.31.61.4-0.7-0.7-1.7-0.61.0-1.8-2.5-2.4-2.5-1.8
Pavlov. Cond. lever contacts1.72.04.30.81.9-0.9-0.6-1.2-0.80.9-1.4-2.0-1.8-2.1-1.7
Pavlov. Cond. magazine entry number1.62.04.3-1.30.40.61.02.00.3-1.11.92.12.11.70.6
Pavlov. Cond. intertrial magazine entries1.41.63.60.7-1.91.51.21.31.3-1.41.31.11.21.20.8
Pavlov. Cond. lever-magazine prob. diff.1.21.43.51.80.60.0-0.1-1.10.10.4-1.3-1.9-1.8-1.8-0.9
Pavlov. Cond. response bias1.72.14.51.10.3-0.7-1.0-1.8-0.61.1-1.8-2.1-2.1-2.0-1.1
Pavlov. Cond. lever latency3.14.25.7-1.42.3-2.4-2.1-2.3-2.42.2-2.0-1.8-1.8-1.9-1.7
Pavlov. Cond. magazine entry latency1.92.35.2-1.2-1.30.70.61.70.7-1.01.72.32.02.11.8
Pavlov. Cond. change in total contacts2.43.96.6-0.2-2.61.71.42.01.7-1.61.92.32.22.52.4
Pavlov. Cond. index score2.73.75.70.0-2.21.71.52.11.7-1.61.92.32.12.42.3
Pavlov. Cond. latency score2.73.65.20.1-2.11.61.52.11.7-1.71.92.32.12.32.2
Pavlov. Cond. lever contacts3.14.36.31.2-2.52.32.02.32.3-2.22.12.02.02.11.8
Pavlov. Cond. magazine entry number2.12.55.20.81.2-1.0-1.0-1.9-0.91.2-1.7-2.3-2.0-2.1-2.0
Pavlov. Cond. intertrial magazine entries0.50.72.51.60.31.21.40.61.0-0.90.5-0.2-0.0-0.10.2
Pavlov. Cond. lever-magazine prob. diff.2.63.45.7-0.2-2.01.51.42.01.6-1.51.82.32.12.42.3
Pavlov. Cond. response bias2.73.65.00.3-2.11.91.62.11.8-1.81.92.22.12.21.9
Time in closed arm before self-admin0.91.12.9-1.2-0.1-1.2-1.4-1.7-1.31.3-1.2-0.8-0.7-0.5-0.1
Time in closed arm after self-admin2.42.54.5-1.51.6-1.9-1.9-1.7-2.11.8-1.6-1.3-1.3-1.3-0.8
Time in open arm before self-admin0.70.75.30.72.30.10.41.00.2-0.50.5-0.2-0.1-0.7-0.6
Time in open arm after self-admin0.70.71.10.4-0.90.90.81.11.0-0.91.00.90.90.80.4
Bone: periosteal estimation0.51.04.62.1-1.61.20.70.21.4-0.90.2-0.5-0.2-0.1-0.2
Bone: periosteal perimeter1.93.28.02.4-0.0-0.5-0.8-1.9-0.20.8-2.0-2.8-2.5-2.5-1.8
Bone: post-yield work0.10.10.2-0.10.10.20.20.40.2-0.30.50.30.40.2-0.1
Progressive ratio test 1 active lever presses0.30.41.30.7-1.10.70.80.40.7-0.60.40.40.30.50.5
Progressive ratio test 1 breakpoint0.30.41.40.8-1.20.70.80.40.7-0.60.30.30.30.50.5
Progressive ratio test 1 inactive lever presses2.53.77.02.4-1.12.62.62.32.4-2.21.61.01.01.11.1
Progressive ratio test 2 active lever presses0.20.20.50.4-0.60.50.60.50.3-0.40.30.30.20.30.7
Progressive ratio test 2 breakpoint0.20.20.50.4-0.70.60.60.50.3-0.40.30.30.20.30.7
Progressive ratio test 2 inactive lever presses0.10.20.50.7-0.60.60.60.40.3-0.1-0.1-0.1-0.3-0.10.2
Incentive Sensitization - Responses0.10.20.90.3-0.90.20.30.50.2-0.30.20.10.10.10.7
Incentive Sensitization - Breakpoint0.10.10.60.2-0.80.20.30.50.2-0.20.10.10.10.10.7
Sum of active levers in priming session hrs 5-61.31.24.70.3-2.20.71.00.91.2-0.60.21.10.81.80.9
Progressive ratio0.20.31.0-1.0-0.2-0.5-0.6-0.1-0.70.6-0.20.30.10.2-0.9
Food seeking constrained by brief footshock0.20.30.9-0.50.3-0.3-0.3-1.0-0.70.8-0.8-0.2-0.5-0.20.2
Seeking ratio, punishment vs. effort0.20.31.80.4-0.40.50.4-0.00.5-0.50.40.30.40.41.4
Retroperitoneal fat weight2.510.519.84.4-2.94.54.22.84.1-3.82.51.51.61.82.8
Reaction time number correct5.210.014.80.9-3.43.22.93.82.9-3.53.83.53.63.22.0
Reaction time mean minus median0.51.22.0-0.40.5-1.2-1.3-1.4-1.11.1-1.2-1.2-1.2-1.2-0.8
Reaction time mean minus median AUC0.30.92.10.11.1-0.8-0.9-0.9-0.70.7-0.7-1.2-1.1-1.5-1.0
Reaction time num false alarms0.20.20.8-0.6-0.9-0.5-0.7-0.60.10.3-0.10.20.30.40.4
Reaction time num false alarms AUC0.20.30.9-0.8-0.7-0.7-0.9-0.6-0.10.3-0.00.20.30.40.0
Reaction time trials correct on left5.210.014.80.9-3.43.22.93.82.9-3.53.83.53.63.22.0
Reaction time trials on left5.410.215.10.9-3.33.32.93.92.9-3.53.93.53.63.22.0
Reaction time mean0.40.74.10.8-2.00.80.30.20.7-0.70.50.40.50.50.7
Reaction time mean AUC0.50.83.10.8-1.81.00.50.51.0-1.00.90.60.70.70.6
Median of all reaction times1.01.46.31.0-2.51.20.60.61.1-1.21.00.80.91.01.0
Reaction time omissions0.20.31.11.1-0.70.50.30.60.8-0.60.50.00.20.1-0.3
Reaction time false alarm rate2.12.95.7-1.21.1-2.3-2.2-2.4-1.52.0-1.9-1.5-1.5-1.2-1.0
Reaction time premature initiation rate0.50.62.6-1.6-0.2-0.7-0.9-0.6-0.70.7-0.20.50.40.71.2
Reaction time premature initiations1.83.25.7-1.0-2.11.20.81.61.0-1.31.92.42.32.42.3
Std. dev. reaction times0.10.21.2-0.5-1.1-0.4-0.8-0.4-0.20.20.10.20.20.20.1
Reaction time trials completed5.410.215.10.9-3.33.32.93.92.9-3.53.93.53.63.22.0
Reaction time trials AUC5.410.315.30.9-3.43.32.93.92.9-3.63.93.53.63.22.0
Run reversals in cocaine runway, females1.51.55.7-1.0-2.40.2-0.00.50.4-0.71.11.51.61.61.2
Run reversals in cocaine runway, males0.80.82.91.0-0.50.1-0.2-0.70.00.4-1.1-1.3-1.2-0.9-1.7
Latency to leave start box in cocaine runway0.10.10.5-0.7-0.4-0.1-0.2-0.2-0.40.00.30.50.50.30.1
Latency to leave start box in cocaine runway, F0.70.71.7-0.20.20.70.71.20.4-0.91.31.21.20.80.5
Latency to leave start box in cocaine runway, M0.40.41.3-0.6-0.6-0.7-0.6-1.1-0.70.7-0.7-0.3-0.4-0.20.1
Std. dev. time between licks in bursts3.24.36.90.9-0.32.12.42.62.3-2.52.62.02.41.91.6
Total sessions with >9 infusions0.10.10.2-0.20.4-0.2-0.00.0-0.40.10.00.20.00.1-0.5
Short access day 1 total inactive lever presses0.20.31.90.61.40.40.40.40.4-0.40.50.00.2-0.20.4
Short access day 10 total inactive lever presses0.71.84.42.1-0.72.11.81.21.9-1.50.90.20.30.30.6
Short access day 1 total infusions0.30.41.5-1.20.9-0.6-0.5-0.3-0.90.40.10.60.40.4-0.1
Short access day 10 total infusions0.20.31.21.10.10.81.00.30.7-0.4-0.1-0.2-0.3-0.10.2
Short access total infusions0.10.10.40.1-0.20.30.60.20.2-0.30.30.60.30.60.5
Short access day 1 locomotion0.30.40.7-0.7-0.2-0.7-0.7-0.8-0.80.7-0.6-0.4-0.4-0.3-0.6
Short access day 10 total locomotion0.71.22.0-0.31.4-1.0-0.9-1.0-0.81.3-1.4-1.2-1.3-1.1-0.9
Short access total locomotion0.60.81.2-0.11.1-0.7-0.6-0.9-0.70.9-1.1-1.0-1.1-0.9-0.9
One hour access (0.3 mA shock)0.40.50.90.4-0.80.70.90.50.6-0.80.60.70.60.70.7
Compulsive drug intake1.21.43.01.2-1.71.11.01.11.3-1.41.30.81.11.00.6
One hour access (shock baseline)0.00.10.2-0.00.4-0.10.1-0.3-0.10.1-0.1-0.3-0.3-0.5-0.0
Social response proportion0.30.30.8-0.3-0.10.60.40.90.3-0.40.70.80.70.7-0.0
Social responses0.10.20.5-0.10.20.60.50.70.1-0.40.50.40.40.2-0.4
Social time0.20.20.5-0.1-0.30.70.40.70.2-0.40.50.70.60.60.1
Soleus weight0.30.95.02.2-0.20.80.4-0.20.8-0.6-0.1-1.1-0.8-1.1-0.8
Bone: stiffness0.20.31.11.0-1.00.60.30.00.8-0.60.2-0.30.0-0.1-0.3
Tibialis anterior weight0.10.31.80.2-1.40.4-0.5-0.10.3-0.40.50.20.40.3-0.7
Time to tail flick, vehicle, before self-admin0.80.93.4-0.61.8-0.8-0.9-0.6-0.90.7-0.5-0.6-0.5-0.8-1.5
Time to tail flick, vehicle, after self-admin1.82.413.9-1.33.7-1.7-1.5-0.9-1.51.3-0.7-0.7-0.7-1.2-1.1
Time to tail flick, test, before self-admin0.70.71.5-0.60.6-0.8-1.0-1.1-1.00.9-0.8-0.6-0.6-0.6-1.2
Time to tail flick, test, after self-admin1.81.95.6-1.02.4-1.3-1.2-0.8-1.61.4-1.2-0.9-1.2-1.2-1.6
Delta time to tail flick, vehicle, before/after SA0.40.40.90.41.00.50.80.80.6-0.50.70.50.40.20.9
Delta time to tail flick, test, before/after SA0.40.40.7-0.70.6-0.8-0.6-0.4-0.80.8-0.7-0.4-0.6-0.4-0.4
Tibia length2.05.628.15.3-0.91.21.1-1.21.2-0.5-1.7-3.4-3.0-2.8-0.8
Ambulatory time before self-admin0.81.34.52.1-1.11.41.50.81.8-1.00.20.00.00.50.4
Ambulatory time after self-admin1.61.93.41.0-1.01.61.81.71.4-1.51.21.31.11.31.0
Bone: tissue strength1.11.12.81.70.11.51.61.11.4-1.30.80.30.30.20.4
Total heroin consumption0.10.20.60.50.60.30.80.60.40.0-0.30.1-0.20.30.0
Bone: trabecular number0.30.52.10.0-1.4-0.4-1.0-0.7-0.40.3-0.4-0.6-0.5-0.5-0.9
Bone: trabecular spacing4.96.510.60.8-0.92.63.03.32.6-2.82.92.82.82.72.2
Bone: trabecular thickness1.51.93.60.50.0-0.9-1.1-1.9-0.91.4-1.9-1.9-1.8-1.5-1.0
Bone: trabecular tissue density0.30.52.0-1.21.4-1.1-0.7-0.3-0.70.6-0.10.10.1-0.10.0
Water consumed over 24 hours1.31.89.9-0.43.1-1.0-0.2-0.7-1.21.2-1.3-1.1-1.4-1.3-0.7
Number of responses in last shaping day0.20.32.20.51.50.20.10.2-0.00.1-0.1-0.4-0.4-0.5-0.5