Hub : Genes

Ndc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ndc1 0.1 0.05 1.2e-07 0.09 0.08 0.09 0.09 1.4e-08 4.1e-08 7.7e-09 1.4e-08
2 Adipose mRNA stability Ndc1 0.03 0.02 7.5e-04 0.01 0.01 -0 0 2.5e-02 2.7e-02 8.0e-01 1.1e-01
3 Adipose gene expression Ndc1 0.05 0.03 2.3e-05 0.03 0.02 0.01 0.01 4.7e-04 1.3e-03 1.2e-02 7.5e-03
4 pVTA gene expression Ndc1 0.06 0.04 1.6e-04 0.04 0.04 0.04 0.03 3.7e-04 6.3e-04 2.8e-04 2.2e-03
5 IL gene expression Ndc1 0.28 0.12 2.0e-04 0.22 0.15 0.17 0.19 4.5e-06 1.6e-04 6.2e-05 2.3e-05
6 BLA gene expression Ndc1 0.21 0.09 3.9e-10 0.12 0.2 0.19 0.19 4.5e-07 7.9e-11 2.9e-10 1.9e-10
7 NAcc gene expression Ndc1 0.09 0.04 1.4e-14 0.05 0.1 0.1 0.1 2.4e-08 6.1e-15 1.8e-15 2.3e-15
8 PL gene expression Ndc1 0.07 0.04 1.2e-07 0.02 0.05 0.05 0.05 1.1e-03 3.6e-06 1.5e-06 1.9e-06
9 Brain gene expression Ndc1 0.16 0.08 9.9e-13 0.13 0.13 0.12 0.14 2.5e-12 1.7e-12 6.0e-11 1.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.11.51.1-0.9-0.5-0.8-1.2-1.2-1.1-1.1-1.2
Area under the delay curve0.40.51.3-1.2-0.1-0.1-0.00.70.60.70.81.1
BMI with tail0.82.87.00.62.61.92.10.31.91.61.51.1
BMI without tail0.41.13.01.61.71.30.6-1.20.70.60.20.0
Body weight0.52.25.00.82.21.81.8-0.21.61.61.31.0
Weight adjusted by age0.20.30.60.80.60.60.5-0.70.20.10.2-0.2
Bone surface0.10.10.30.3-0.6-0.1-0.2-0.2-0.4-0.2-0.3-0.2
Bone volume0.10.10.40.7-0.10.40.3-0.3-0.10.1-0.0-0.1
Breakpoint value in progressive ratio session0.00.00.1-0.4-0.2-0.20.20.4-0.10.10.00.1
Number of licking bursts0.40.71.3-0.50.50.71.20.80.90.81.01.0
Context. condit. distance diff. score1.21.42.81.4-0.5-0.4-0.6-1.2-1.4-1.4-1.5-1.7
Locomotion velocity, session 11.01.02.6-0.9-1.6-1.3-0.60.9-1.1-1.0-0.8-0.5
Locomotion distance, session 10.10.10.1-0.3-0.20.10.20.40.10.30.20.4
Locomotion velocity, session 20.70.92.6-0.9-1.6-1.1-0.80.9-0.9-0.7-0.5-0.2
Locomotion distance, session 20.60.91.6-0.00.81.10.70.61.11.31.01.2
Locomotion velocity, session 30.10.10.7-0.0-0.8-0.0-0.20.3-0.3-0.2-0.20.0
Locomotion distance, session 30.20.20.70.90.40.2-0.0-0.8-0.2-0.2-0.4-0.5
Stereotopy head waving bouts, day 30.70.81.7-1.00.00.50.50.90.81.01.21.3
Stereotopy head waving duration, day 30.40.41.0-0.9-0.30.20.20.80.50.60.81.0
Locomotion velocity, session 70.20.21.01.0-0.20.6-0.2-0.1-0.3-0.2-0.4-0.6
Locomotion distance, session 71.01.33.81.9-0.10.3-0.9-1.3-0.9-0.7-1.3-1.6
Stereotopy head waving bouts, day 70.70.83.2-1.8-1.2-0.9-0.31.0-0.2-0.20.30.7
Stereotopy head waving duration, day 70.60.82.7-1.7-1.3-0.9-0.31.0-0.2-0.20.30.7
Locomotion velocity, session 80.70.91.8-0.2-1.3-1.0-1.0-0.0-1.1-1.2-1.0-0.7
Locomotion distance, session 80.40.52.21.5-0.10.5-0.2-0.9-0.5-0.4-0.7-0.7
Degree of sensitization distance0.20.21.11.00.10.5-0.2-0.4-0.3-0.1-0.4-0.7
Degree of sensitization stereotypy0.50.51.9-1.4-1.0-0.6-0.20.9-0.1-0.10.20.6
Conditioned locomotion0.10.10.3-0.00.40.40.50.30.30.40.40.3
Cocaine response after cond. corrected0.60.72.00.81.41.10.90.00.90.90.50.4
Cocaine response after cond. not corrected0.91.13.01.01.71.31.3-0.11.01.00.60.4
Cocaine response before conditioning0.10.10.30.50.40.20.4-0.40.0-0.0-0.1-0.2
Saline control response0.30.40.80.5-0.2-0.6-0.7-0.8-0.5-0.5-0.9-0.7
Bone: connectivity density0.81.31.80.5-1.4-1.0-1.4-0.9-1.3-1.2-1.3-1.0
Bone: cortical apparent density1.72.33.50.1-1.5-1.8-1.6-1.2-1.8-1.9-1.6-1.4
Bone: cortical area0.61.02.11.11.41.41.0-0.31.01.00.70.4
Bone: cortical porosity1.81.94.4-2.10.0-0.11.42.11.01.11.31.6
Bone: cortical porosity2.62.88.1-2.8-0.4-0.41.32.61.01.21.62.0
Bone: cortical thickness1.83.15.61.02.32.42.10.31.91.91.71.2
Bone: cortical thickness1.31.53.60.61.71.41.90.51.21.21.00.6
Bone: cortical tissue density1.82.53.70.0-1.5-1.9-1.6-1.2-1.9-1.9-1.7-1.5
Condit. Reinf. active minus inactive responses0.30.31.01.00.80.60.6-0.40.10.2-0.1-0.5
Condit. Reinf. active-inactive response ratio0.50.51.71.30.90.90.8-0.50.10.2-0.1-0.5
Condit. Reinf. active responses0.70.91.6-0.11.20.91.30.81.01.00.80.5
Condit. Reinf. inactive responses0.80.92.5-1.40.30.00.31.60.90.80.91.1
Incentive salience index mean0.81.02.50.91.61.31.40.20.81.00.60.1
Condit. Reinf. lever presses0.91.33.00.61.71.41.50.61.11.30.80.4
Condit. Reinf. active minus inactive responses1.11.44.82.20.40.7-0.7-2.0-0.5-0.4-0.9-1.2
Condit. Reinf. active-inactive response ratio2.22.55.82.40.10.0-1.3-2.4-1.2-1.2-1.7-1.9
Condit. Reinf. active responses0.81.14.02.00.51.0-0.2-1.8-0.2-0.1-0.4-0.9
Condit. Reinf. inactive responses0.50.61.30.40.81.10.9-0.10.90.91.00.5
Condit. Reinf. lever presses0.30.40.80.5-0.5-0.4-0.9-0.8-0.6-0.5-0.7-0.7
Condit. Reinf. lever reinforcers received0.50.72.71.70.40.9-0.2-1.5-0.00.0-0.2-0.6
Conditioned reinforcement - actives0.40.61.71.31.30.90.5-0.90.40.30.0-0.3
Conditioned reinforcement - inactives0.10.20.5-0.40.10.10.70.20.40.40.60.7
Conditioned locomotion0.60.82.41.50.50.1-0.4-1.2-0.5-0.6-0.9-1.1
Patch foraging indifference point 0 sec0.10.10.50.60.70.40.1-0.40.30.2-0.1-0.0
Patch foraging indifference point AUC0.71.02.21.3-0.5-0.2-1.1-1.5-1.0-0.8-1.1-1.2
Delay disc. indifference point, 0s delay0.20.20.9-1.0-0.5-0.4-0.20.60.10.20.30.6
Delay disc. indifference point, 16s delay1.61.83.5-0.71.11.20.91.11.71.51.61.9
Delay disc. indifference point, 2s delay0.00.00.1-0.1-0.2-0.2-0.0-0.3-0.10.10.1-0.1
Delay disc. indifference point, 24s delay0.40.41.3-0.9-0.50.1-0.41.10.40.30.50.9
Delay disc. indifference point, 4s delay0.40.41.3-1.10.1-0.20.10.40.60.60.70.8
Delay disc. indifference point, 8s delay0.30.30.7-0.7-0.10.1-0.10.80.50.60.50.8
Indifference point function ln k0.20.40.7-0.20.80.50.80.60.80.60.60.7
Indifference point function log k0.20.40.7-0.20.80.50.80.60.80.60.60.7
Patch foraging total patch changes 0 sec0.10.10.50.50.70.20.1-0.50.20.2-0.10.0
Patch foraging total patch changes 12 sec0.71.01.7-0.3-1.1-1.3-1.3-0.6-1.1-1.0-1.0-0.7
Patch foraging total patch changes 18 sec0.30.51.71.20.60.20.2-1.3-0.2-0.2-0.4-0.7
Patch foraging total patch changes 24 sec0.50.91.50.01.21.01.10.41.11.11.00.9
Patch foraging total patch changes 6 sec0.10.10.30.60.50.2-0.1-0.60.10.2-0.1-0.1
Patch foraging time to switch 0 sec0.61.34.1-2.0-1.5-1.6-0.51.3-0.6-0.60.00.2
Patch foraging water rate 0 sec0.81.83.91.12.01.91.60.01.41.40.90.5
Patch foraging water rate 12 sec1.22.65.91.72.32.41.6-0.41.61.51.10.6
Patch foraging water rate 18 sec0.20.30.5-0.70.10.30.30.60.60.40.60.7
Patch foraging water rate 24 sec0.10.10.20.00.30.40.5-0.10.40.30.30.3
Patch foraging water rate 6 sec1.42.02.9-0.51.41.41.51.51.71.61.31.4
Seeking ratio, delayed vs. immediate footshock1.41.75.72.41.71.81.4-0.80.50.60.2-0.6
Distance traveled before self-admin0.91.15.52.30.61.30.1-1.4-0.20.2-0.4-0.8
Distance traveled after self-admin1.01.34.52.11.31.7-0.1-1.30.50.70.1-0.2
Extensor digitorum longus weight0.62.25.42.32.11.91.5-1.50.70.70.4-0.5
Bone: elastic displacement2.32.78.42.90.30.5-0.5-2.1-1.2-1.2-1.5-2.3
Bone: elastic work1.01.34.92.20.50.7-0.4-1.4-0.6-0.6-1.0-1.6
Bone: endosteal estimation0.51.01.80.9-0.4-0.8-0.8-1.1-1.1-1.1-1.3-1.3
Bone: endosteal perimeter0.20.40.7-0.4-0.7-0.8-0.80.1-0.6-0.6-0.6-0.4
Epididymis fat weight0.10.41.8-1.3-0.5-0.6-0.50.70.10.00.30.8
Delta time in closed arm before/after self-admin4.44.112.32.70.1-0.5-1.1-3.5-1.7-1.6-2.0-2.4
Delta time in open arm before/after self-admin1.11.13.5-1.7-0.1-0.2-0.11.90.80.60.81.2
Diff in mean of infusions in LGA sessions0.10.10.2-0.10.20.20.50.50.30.40.40.4
Delay discount exponential model param0.40.51.41.20.10.10.1-0.6-0.6-0.6-0.7-1.1
Extinction: sum of active levers before priming0.10.10.30.10.3-0.10.5-0.1-0.2-0.1-0.2-0.4
Active lever presses in extinction session 61.31.32.20.31.21.41.50.61.21.41.10.8
Bone: final force0.00.00.1-0.0-0.1-0.3-0.2-0.2-0.2-0.1-0.2-0.2
Bone: final moment0.00.00.00.10.0-0.1-0.1-0.2-0.10.0-0.1-0.2
Food consumed during 24 hour testing period0.30.40.9-0.50.40.4-0.20.40.90.90.71.0
Glucose0.10.10.50.70.40.4-0.1-0.3-0.1-0.0-0.2-0.4
Heart weight0.81.23.30.51.61.11.80.01.11.00.90.6
Delay discount hyperbolic model param0.40.51.51.20.20.30.1-0.6-0.6-0.6-0.7-1.0
Intermittent access intake day 1-15 change0.10.31.00.71.00.50.1-0.80.30.1-0.1-0.4
Intermittent access intake escalation0.10.21.10.51.00.50.2-0.60.40.20.1-0.2
Intermittent access intake escalation 20.00.10.3-0.00.5-0.1-0.1-0.40.2-0.0-0.0-0.1
Intermitt. access day 1 inactive lever presses0.20.92.01.41.21.40.9-0.50.70.80.50.2
Intermitt. access day 15 inactive lever presses0.20.30.7-0.10.60.50.80.30.70.70.60.6
Intermitt. access escalation Index0.10.10.2-0.40.20.10.20.30.40.40.40.5
Intermittent access day 1 total infusions0.20.31.0-1.0-0.4-0.30.50.60.20.30.50.8
Intermittent access day 15 total infusions0.10.20.4-0.40.60.20.60.20.60.40.60.5
Intermittent access terminal intake (last 3 days)0.00.10.40.00.2-0.2-0.1-0.6-0.1-0.2-0.1-0.2
Intermittent access total infusions0.10.10.3-0.6-0.1-0.50.2-0.1-0.0-0.20.10.2
Intermittent access day 1 locomotion0.20.20.7-0.9-0.2-0.60.50.70.0-0.10.20.5
Intermittent access day 15 total locomotion0.00.10.3-0.30.2-0.6-0.1-0.1-0.0-0.2-0.10.0
Intermittent access total locomotion0.10.10.6-0.60.0-0.80.10.1-0.2-0.3-0.20.0
Intermittent access standard deviation0.61.33.40.61.81.31.60.51.21.01.00.5
Left kidney weight2.712.329.63.55.44.93.8-1.13.33.32.51.0
Right kidney weight1.77.819.12.24.43.83.0-0.52.92.92.31.1
Cocaine induced anxiety0.10.20.60.40.80.60.3-0.20.40.30.2-0.1
Post-drug Anxiety0.60.61.20.21.01.01.10.50.80.80.80.5
Baseline Anxiety2.12.44.0-1.30.40.81.82.01.41.61.91.9
Tail length0.10.21.20.7-0.10.0-0.4-1.1-0.2-0.1-0.5-0.2
Length with tail0.10.40.80.90.80.80.4-0.70.50.60.20.2
Length without tail0.72.44.31.02.12.11.70.11.71.81.41.0
Times rat made contact with spout0.20.20.50.70.40.6-0.3-0.60.30.2-0.10.1
Lifetime Intake0.10.10.5-0.7-0.2-0.60.20.0-0.0-0.20.10.3
Liver weight, left0.10.10.30.2-0.40.1-0.6-0.2-0.3-0.4-0.2-0.2
Liver weight, right0.40.61.00.5-0.6-0.7-0.9-0.8-0.8-1.0-1.0-0.8
Locomotor activity0.50.81.51.20.1-0.1-0.9-0.9-0.7-0.9-1.1-1.2
Locomotor testing distance1.11.95.22.30.60.3-0.9-1.7-1.0-1.0-1.4-2.0
Locomotor testing rearing1.12.25.02.20.2-0.0-1.1-2.2-1.1-1.3-1.5-1.9
Locomotion in novel chamber3.03.95.9-0.02.12.32.11.62.22.42.11.7
Locomotion in novel chamber post-restriction0.50.81.4-0.30.61.01.20.51.01.01.11.1
Fecal boli incidents, locomotor time 10.10.10.2-0.40.1-0.10.00.50.20.30.10.4
Change in fecal boli incidents, locomotor task0.20.20.5-0.6-0.6-0.7-0.50.1-0.3-0.4-0.1-0.0
Time >=10cm from walls, locomotor time 11.71.83.21.1-0.9-0.8-1.2-1.8-1.5-1.5-1.5-1.4
Bouts of movement, locomotor time 10.60.62.5-1.6-0.9-1.1-0.70.5-0.10.10.10.7
Total resting periods, locomotor time 10.80.83.5-1.9-0.7-1.0-0.41.10.10.30.30.9
Rest time, locomotor task time 10.10.20.6-0.8-0.3-0.6-0.30.7-0.1-0.1-0.10.2
Distance moved, locomotor task time 10.20.21.00.9-0.20.4-0.1-1.0-0.2-0.0-0.0-0.4
Vertical activity count, locomotor time 10.10.40.80.80.60.90.3-0.70.50.60.5-0.0
Time >=10cm from walls, locomotor time 20.40.62.01.40.20.3-0.3-1.2-0.5-0.4-0.7-0.9
Bouts of movement, locomotor time 20.10.21.20.1-0.5-0.3-0.3-1.1-0.4-0.2-0.1-0.3
Total resting periods, locomotor time 20.10.20.8-0.0-0.5-0.3-0.3-0.9-0.3-0.1-0.0-0.2
Rest time, locomotor task time 20.30.41.9-1.4-0.4-0.6-0.50.70.20.10.40.6
Distance moved, locomotor task time 20.91.15.02.20.91.30.6-1.30.10.3-0.1-0.7
Vertical activity count, locomotor time 20.81.24.22.11.41.50.8-0.60.50.70.2-0.4
Light reinforcement 10.10.30.70.00.60.60.80.60.60.50.60.4
Light reinforcement 20.81.22.80.71.41.71.10.11.21.11.00.7
Bone: marrow area0.51.01.80.9-0.4-0.8-0.8-1.1-1.1-1.1-1.3-1.4
Bone: maximum diameter0.20.40.6-0.10.50.60.70.30.70.70.70.7
Bone: maximum force0.10.20.30.6-0.1-0.1-0.4-0.5-0.3-0.2-0.5-0.5
Bone: maximum moment0.10.20.60.70.10.1-0.3-0.6-0.3-0.1-0.4-0.5
Mean time between licks in bursts0.71.62.6-0.3-1.6-1.5-1.40.3-1.5-1.4-1.4-1.2
Mean num. licks in bursts0.30.51.21.10.30.1-0.8-1.0-0.4-0.3-0.8-0.8
Cd content in liver2.83.15.31.7-0.9-1.0-1.3-2.3-1.9-2.0-2.0-2.3
Co content in liver1.61.94.42.1-0.20.0-0.9-1.9-1.2-1.1-1.5-1.8
Cu content in liver2.93.55.91.9-0.6-0.7-2.2-2.4-1.8-1.8-2.1-2.3
Fe content in liver0.50.62.21.51.01.00.5-0.90.20.3-0.1-0.6
K content in liver0.30.31.00.2-0.6-0.1-1.0-0.1-0.5-0.3-0.5-0.5
Mg content in liver0.60.61.0-0.30.70.90.20.80.91.00.80.7
Mn content in liver0.20.20.70.1-0.5-0.4-0.10.0-0.7-0.5-0.5-0.8
Na content in liver0.50.51.10.7-0.7-0.4-0.8-0.4-0.9-0.6-0.8-1.0
Rb content in liver0.00.00.1-0.0-0.00.0-0.3-0.2-0.1-0.1-0.1-0.1
Se content in liver0.81.02.41.5-0.30.2-0.9-1.3-0.8-0.9-1.1-1.1
Sr content in liver0.40.41.01.00.00.00.1-0.7-0.6-0.6-0.6-0.9
Zn content in liver0.50.61.1-0.3-1.0-0.9-1.1-0.2-0.8-0.6-0.6-0.5
Bone: minimum diameter0.40.72.31.50.60.3-0.4-1.2-0.3-0.3-0.8-0.9
Time in familiar zone, hab. session 11.01.02.11.5-0.50.2-0.7-1.1-0.9-1.0-1.0-1.3
Time in novel zone, hab. session 10.60.61.00.2-0.5-1.0-0.7-0.8-0.8-0.8-0.9-0.7
Total zone transitions, hab. session 10.00.00.00.0-0.2-0.00.2-0.2-0.00.10.20.1
Total locomotion distance, hab. session 10.30.40.70.30.70.80.80.10.70.80.70.5
Locomotion velocity, hab. session 10.60.81.3-0.70.60.50.90.81.01.11.11.1
Time in familiar zone, hab. session 21.61.72.71.6-0.9-0.1-1.5-1.6-1.2-1.2-1.4-1.5
Time in novel zone, hab. session 20.10.10.2-0.50.4-0.40.40.30.10.10.10.2
Total zone transitions, hab. session 20.00.10.20.40.00.3-0.1-0.30.10.20.00.1
Total locomotion distance, hab. session 20.40.51.40.40.71.20.60.30.80.90.70.6
Locomotion velocity, hab. session 20.71.02.00.20.81.40.90.61.11.21.10.9
Novel to familiar place preference ratio0.40.40.7-0.20.70.60.30.30.90.80.70.7
Novelty place preference0.20.20.5-0.30.40.40.10.20.70.70.60.6
Time in novel zone, NPP test0.10.10.2-0.20.30.2-0.0-0.00.40.40.40.4
Total zone transitions, NPP test0.50.71.40.81.21.11.1-0.20.70.70.60.2
Total locomotion distance, NPP test0.81.12.40.91.31.51.20.01.01.10.90.4
Locomotion velocity, NPP test1.21.73.70.91.61.91.50.31.41.51.30.7
Intraocular pressure0.50.71.0-1.00.60.40.80.80.90.81.00.9
Delta distance traveled before/after self-admin0.80.91.7-0.41.20.80.60.51.31.01.01.1
Delta ambulatory time before/after self-admin0.50.61.2-0.51.10.60.40.21.10.80.80.9
Parametrial fat weight0.20.51.2-0.80.20.4-0.00.90.81.00.71.1
Pavlov. Cond. lever latency1.51.93.1-0.3-1.7-1.6-1.6-0.6-1.4-1.8-1.4-1.0
Pavlov. Cond. magazine entry latency0.20.30.8-0.6-0.6-0.9-0.6-0.0-0.6-0.4-0.4-0.3
Pavlov. Cond. change in total contacts0.10.10.4-0.30.00.20.30.20.30.70.50.4
Pavlov. Cond. index score0.20.30.60.10.70.60.60.00.50.80.60.3
Pavlov. Cond. latency score0.40.51.1-0.10.80.70.80.20.71.00.80.6
Pavlov. Cond. lever contacts1.11.42.40.11.41.41.40.61.21.61.30.9
Pavlov. Cond. magazine entry number0.10.20.50.50.60.70.30.10.40.20.10.1
Pavlov. Cond. intertrial magazine entries1.21.52.6-1.01.00.90.81.31.51.31.41.6
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.10.80.70.60.10.60.90.60.4
Pavlov. Cond. response bias0.00.00.10.20.30.20.2-0.10.00.30.1-0.1
Pavlov. Cond. lever latency0.00.10.40.00.10.10.60.2-0.0-0.00.1-0.0
Pavlov. Cond. magazine entry latency1.82.24.60.8-1.2-1.2-2.2-1.5-1.5-1.5-1.7-1.5
Pavlov. Cond. change in total contacts0.10.10.6-0.2-0.5-0.2-0.8-0.0-0.1-0.1-0.20.1
Pavlov. Cond. index score0.70.92.80.3-0.9-0.8-1.7-0.8-0.8-0.8-1.0-0.8
Pavlov. Cond. latency score0.60.82.70.4-0.8-0.6-1.6-0.9-0.8-0.7-0.9-0.7
Pavlov. Cond. lever contacts0.10.10.40.3-0.2-0.1-0.7-0.5-0.2-0.2-0.4-0.3
Pavlov. Cond. magazine entry number1.62.05.3-0.11.71.42.31.11.41.41.41.0
Pavlov. Cond. intertrial magazine entries0.20.31.0-1.0-0.1-0.10.60.90.40.10.60.7
Pavlov. Cond. lever-magazine prob. diff.0.91.13.40.4-0.9-0.9-1.9-0.9-1.0-1.0-1.2-1.0
Pavlov. Cond. response bias0.40.61.40.1-0.8-0.7-1.2-0.7-0.7-0.7-0.8-0.6
Time in closed arm before self-admin0.50.61.9-1.4-0.8-0.5-0.31.40.1-0.00.30.6
Time in closed arm after self-admin0.40.50.90.2-0.3-0.8-0.6-0.9-0.7-0.9-0.8-0.6
Time in open arm before self-admin0.80.92.81.70.40.4-0.3-1.6-0.6-0.3-0.7-1.1
Time in open arm after self-admin0.40.40.7-0.20.70.70.20.60.80.80.60.5
Bone: periosteal estimation0.20.31.31.10.80.50.4-0.70.10.2-0.1-0.4
Bone: periosteal perimeter0.00.10.20.40.30.50.1-0.20.20.30.20.0
Bone: post-yield work0.10.10.2-0.2-0.4-0.5-0.30.3-0.2-0.3-0.3-0.2
Progressive ratio test 1 active lever presses0.40.51.2-0.50.60.31.10.80.70.60.70.8
Progressive ratio test 1 breakpoint0.40.51.2-0.40.70.31.10.80.70.60.70.8
Progressive ratio test 1 inactive lever presses0.10.10.70.30.40.30.8-0.10.20.20.20.1
Progressive ratio test 2 active lever presses0.10.10.4-0.10.40.20.70.30.30.30.40.3
Progressive ratio test 2 breakpoint0.10.20.5-0.20.40.20.70.40.40.40.40.3
Progressive ratio test 2 inactive lever presses0.10.20.5-0.6-0.1-0.10.40.30.30.40.50.7
Incentive Sensitization - Responses0.30.41.3-1.1-0.1-0.20.30.90.40.40.60.7
Incentive Sensitization - Breakpoint0.20.30.9-0.9-0.0-0.10.30.80.40.40.50.6
Sum of active levers in priming session hrs 5-60.50.41.91.40.40.70.7-0.7-0.2-0.2-0.2-0.7
Progressive ratio0.91.52.6-0.90.51.01.11.21.31.31.51.6
Food seeking constrained by brief footshock2.93.65.2-0.1-2.3-2.1-2.2-1.6-2.1-2.1-2.0-1.5
Seeking ratio, punishment vs. effort4.66.68.71.2-2.1-2.4-2.7-2.7-2.9-2.8-2.9-2.8
Retroperitoneal fat weight0.20.63.1-1.8-0.6-0.9-0.50.80.10.10.30.8
Reaction time number correct0.00.00.10.00.1-0.20.3-0.2-0.1-0.3-0.2-0.1
Reaction time mean minus median0.10.31.1-1.0-0.7-0.6-0.60.30.10.00.30.6
Reaction time mean minus median AUC0.00.10.3-0.4-0.6-0.4-0.5-0.1-0.2-0.2-0.10.1
Reaction time num false alarms0.91.32.1-0.01.01.30.90.91.31.41.31.2
Reaction time num false alarms AUC1.21.93.00.31.51.71.30.91.61.71.41.3
Reaction time trials correct on left0.00.00.10.00.1-0.20.3-0.2-0.1-0.3-0.2-0.1
Reaction time trials on left0.00.00.1-0.00.1-0.20.2-0.1-0.1-0.2-0.1-0.1
Reaction time mean0.71.24.8-2.2-0.9-0.8-0.71.20.40.30.71.3
Reaction time mean AUC0.50.83.0-1.7-1.0-0.9-0.90.70.0-0.10.30.8
Median of all reaction times1.01.45.8-2.4-0.9-0.8-0.51.50.50.30.81.4
Reaction time omissions0.81.13.3-1.6-0.2-0.00.01.01.10.91.21.8
Reaction time false alarm rate1.21.73.00.41.41.71.11.01.51.71.31.1
Reaction time premature initiation rate0.50.71.60.2-0.6-0.8-1.3-0.1-0.8-0.9-1.0-0.9
Reaction time premature initiations0.40.81.30.2-0.7-1.0-1.1-0.2-0.9-1.1-1.2-1.0
Std. dev. reaction times0.10.20.8-0.9-0.5-0.5-0.60.20.10.10.20.5
Reaction time trials completed0.00.00.1-0.00.1-0.20.2-0.1-0.1-0.2-0.1-0.1
Reaction time trials AUC0.00.00.10.10.3-0.10.4-0.20.0-0.1-0.1-0.0
Run reversals in cocaine runway, females1.01.03.5-1.9-0.5-0.4-0.11.70.50.40.71.1
Run reversals in cocaine runway, males1.01.02.11.41.41.41.0-1.00.60.40.4-0.1
Latency to leave start box in cocaine runway1.11.23.3-0.31.11.01.81.11.00.91.20.8
Latency to leave start box in cocaine runway, F2.02.35.8-0.21.41.62.41.31.51.41.81.3
Latency to leave start box in cocaine runway, M0.10.10.4-0.3-0.2-0.6-0.4-0.1-0.4-0.4-0.4-0.3
Std. dev. time between licks in bursts1.01.33.2-1.3-1.8-1.6-1.01.0-1.1-1.1-0.7-0.4
Total sessions with >9 infusions0.20.31.4-1.2-0.3-0.90.20.10.1-0.10.30.6
Short access day 1 total inactive lever presses1.11.52.40.41.61.41.50.21.41.31.41.0
Short access day 10 total inactive lever presses0.20.51.61.30.60.90.1-1.20.40.50.10.1
Short access day 1 total infusions0.20.30.9-1.00.0-0.30.70.50.40.30.60.7
Short access day 10 total infusions0.10.10.4-0.60.2-0.10.60.00.30.20.40.5
Short access total infusions0.20.31.3-1.2-0.3-0.70.30.30.1-0.00.30.6
Short access day 1 locomotion0.10.20.70.20.80.10.3-0.80.30.20.10.1
Short access day 10 total locomotion0.61.12.4-0.80.90.41.00.91.31.11.21.5
Short access total locomotion0.20.20.6-0.3-0.3-0.8-0.3-0.5-0.3-0.5-0.4-0.1
One hour access (0.3 mA shock)0.50.50.9-0.0-0.6-1.0-0.5-0.9-0.8-0.9-0.8-0.7
Compulsive drug intake0.30.30.7-0.7-0.9-0.9-0.40.3-0.5-0.6-0.4-0.1
One hour access (shock baseline)0.20.30.90.70.90.60.6-0.60.40.40.40.0
Social response proportion0.20.30.8-0.5-0.9-0.6-0.70.1-0.3-0.4-0.2-0.1
Social responses0.91.22.8-0.1-1.7-1.0-1.4-0.3-1.2-1.2-1.1-0.9
Social time0.10.20.80.90.20.80.0-0.30.20.0-0.1-0.1
Soleus weight1.44.09.82.53.13.02.0-0.81.61.71.0-0.0
Bone: stiffness0.00.10.3-0.6-0.2-0.30.10.20.10.20.20.4
Tibialis anterior weight2.37.615.11.83.93.63.6-0.32.82.82.51.6
Time to tail flick, vehicle, before self-admin2.02.14.0-0.41.61.22.01.41.61.51.61.3
Time to tail flick, vehicle, after self-admin1.52.03.8-0.91.01.12.01.81.51.21.61.4
Time to tail flick, test, before self-admin1.11.13.80.22.01.21.20.51.10.80.80.4
Time to tail flick, test, after self-admin1.01.11.80.41.21.31.30.71.11.11.10.7
Delta time to tail flick, vehicle, before/after SA0.30.20.80.20.20.90.60.40.50.40.60.4
Delta time to tail flick, test, before/after SA0.20.20.4-0.3-0.50.10.30.60.20.50.50.6
Tibia length0.30.81.1-1.00.90.20.91.00.90.90.91.0
Ambulatory time before self-admin0.91.46.62.60.41.10.0-1.5-0.5-0.1-0.7-1.2
Ambulatory time after self-admin0.60.72.91.71.01.10.1-1.10.20.3-0.2-0.4
Bone: tissue strength1.71.72.80.8-1.0-1.0-1.7-1.1-1.4-1.4-1.5-1.5
Total heroin consumption0.20.20.7-0.8-0.6-0.50.30.6-0.2-0.10.10.1
Bone: trabecular number1.42.33.11.2-1.1-1.0-1.5-1.7-1.6-1.7-1.7-1.8
Bone: trabecular spacing2.22.94.3-0.71.41.62.01.51.92.02.11.8
Bone: trabecular thickness0.91.21.80.8-1.0-0.7-1.4-1.0-1.2-1.0-1.3-1.2
Bone: trabecular tissue density0.00.10.20.3-0.40.2-0.3-0.4-0.20.00.1-0.0
Water consumed over 24 hours1.01.44.62.10.90.7-0.4-2.1-0.3-0.3-0.9-1.1
Number of responses in last shaping day1.11.22.81.41.71.61.0-0.40.80.90.6-0.1