Hub : Genes

Ndc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Ndc1 0.1 0.05 1.2e-07 0.09 0.08 0.09 0.09 1.4e-08 4.1e-08 7.7e-09 1.6e-08
2 Adipose mRNA stability Ndc1 0.03 0.02 7.5e-04 0.01 0.01 -0 0 2.5e-02 2.7e-02 8.0e-01 1.1e-01
3 Adipose gene expression Ndc1 0.05 0.03 2.3e-05 0.03 0.02 0.01 0.01 4.7e-04 1.3e-03 1.2e-02 7.4e-03
4 pVTA gene expression Ndc1 0.06 0.04 1.6e-04 0.04 0.04 0.04 0.03 3.7e-04 6.3e-04 2.8e-04 2.3e-03
5 IL gene expression Ndc1 0.28 0.12 2.0e-04 0.22 0.15 0.17 0.19 4.5e-06 1.6e-04 6.2e-05 2.3e-05
6 BLA gene expression Ndc1 0.21 0.09 3.9e-10 0.12 0.2 0.19 0.19 4.5e-07 7.9e-11 2.9e-10 1.8e-10
7 NAcc gene expression Ndc1 0.09 0.04 1.4e-14 0.05 0.1 0.1 0.1 2.4e-08 6.1e-15 1.8e-15 2.3e-15
8 PL gene expression Ndc1 0.07 0.04 1.2e-07 0.02 0.05 0.05 0.05 1.1e-03 3.6e-06 1.5e-06 1.8e-06
9 Brain gene expression Ndc1 0.16 0.08 9.9e-13 0.13 0.13 0.12 0.14 2.5e-12 1.7e-12 6.0e-11 1.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.11.5-1.10.90.50.81.2-1.21.11.1-1.2
Area under the delay curve0.30.51.31.20.10.10.0-0.70.6-0.7-0.81.1
BMI with tail0.82.87.0-0.6-2.6-1.9-2.1-0.31.9-1.6-1.51.1
BMI without tail0.21.13.0-1.6-1.7-1.3-0.61.20.7-0.6-0.20.0
Body weight0.52.25.0-0.8-2.2-1.8-1.80.21.6-1.6-1.31.1
Weight adjusted by age0.10.30.6-0.8-0.6-0.6-0.50.70.2-0.1-0.2-0.2
Bone surface0.00.10.3-0.30.60.10.20.2-0.40.20.3-0.2
Bone volume0.00.10.4-0.70.1-0.4-0.30.3-0.1-0.10.0-0.1
Breakpoint value in progressive ratio session0.00.00.10.40.20.2-0.2-0.4-0.1-0.1-0.00.1
Number of licking bursts0.20.71.30.5-0.5-0.7-1.2-0.80.9-0.8-1.01.0
Context. condit. distance diff. score1.21.42.8-1.40.50.40.61.2-1.41.41.5-1.7
Locomotion velocity, session 10.91.02.60.91.61.30.6-0.9-1.11.00.8-0.5
Locomotion distance, session 10.00.10.10.30.2-0.1-0.2-0.40.1-0.3-0.20.4
Locomotion velocity, session 20.70.92.60.91.61.10.8-0.9-0.90.70.5-0.2
Locomotion distance, session 20.60.91.60.0-0.8-1.1-0.7-0.61.1-1.3-1.01.2
Locomotion velocity, session 30.10.10.70.00.80.00.2-0.3-0.30.20.20.0
Locomotion distance, session 30.20.20.7-0.9-0.4-0.20.00.8-0.20.20.4-0.5
Stereotopy head waving bouts, day 30.60.81.71.0-0.0-0.5-0.5-0.90.8-1.0-1.21.3
Stereotopy head waving duration, day 30.30.41.00.90.3-0.2-0.2-0.80.5-0.6-0.81.0
Locomotion velocity, session 70.20.21.0-1.00.2-0.60.20.1-0.30.20.4-0.6
Locomotion distance, session 71.01.33.8-1.90.1-0.30.91.3-0.90.71.3-1.6
Stereotopy head waving bouts, day 70.70.83.21.81.20.90.3-1.0-0.20.2-0.30.7
Stereotopy head waving duration, day 70.60.82.71.71.30.90.3-1.0-0.20.2-0.30.7
Locomotion velocity, session 80.70.91.80.21.31.01.00.0-1.11.21.0-0.7
Locomotion distance, session 80.40.52.2-1.50.1-0.50.20.9-0.50.40.7-0.7
Degree of sensitization distance0.20.21.1-1.0-0.1-0.50.20.4-0.30.10.4-0.7
Degree of sensitization stereotypy0.40.51.91.41.00.60.2-0.9-0.10.1-0.20.6
Conditioned locomotion0.10.10.30.0-0.4-0.4-0.5-0.30.3-0.4-0.40.3
Cocaine response after cond. corrected0.50.72.0-0.8-1.4-1.1-0.9-0.00.9-0.9-0.50.4
Cocaine response after cond. not corrected0.81.13.0-1.0-1.7-1.3-1.30.11.0-1.0-0.60.4
Cocaine response before conditioning0.10.10.3-0.5-0.4-0.2-0.40.40.00.00.1-0.2
Saline control response0.30.40.8-0.50.20.60.70.8-0.50.50.9-0.7
Bone: connectivity density0.81.31.8-0.51.41.01.40.9-1.31.21.3-1.0
Bone: cortical apparent density1.52.33.5-0.11.51.81.61.2-1.81.91.6-1.4
Bone: cortical area0.61.02.1-1.1-1.4-1.4-1.00.31.0-1.0-0.70.4
Bone: cortical porosity1.81.94.42.1-0.00.1-1.4-2.11.0-1.1-1.31.6
Bone: cortical porosity2.62.88.12.80.40.4-1.3-2.61.0-1.2-1.62.0
Bone: cortical thickness1.83.15.6-1.0-2.3-2.4-2.1-0.31.9-1.9-1.71.2
Bone: cortical thickness1.21.53.6-0.6-1.7-1.4-1.9-0.51.2-1.2-1.00.6
Bone: cortical tissue density1.62.53.7-0.01.51.91.61.2-1.91.91.7-1.5
Condit. Reinf. active minus inactive responses0.30.31.0-1.0-0.8-0.6-0.60.40.1-0.20.1-0.5
Condit. Reinf. active-inactive response ratio0.50.51.7-1.3-0.9-0.9-0.80.50.1-0.20.1-0.5
Condit. Reinf. active responses0.70.91.60.1-1.2-0.9-1.3-0.81.0-1.0-0.80.6
Condit. Reinf. inactive responses0.70.92.51.4-0.3-0.0-0.3-1.60.9-0.8-0.91.1
Incentive salience index mean0.81.02.5-0.9-1.6-1.3-1.4-0.20.8-1.0-0.60.1
Condit. Reinf. lever presses0.91.33.0-0.6-1.7-1.4-1.5-0.61.1-1.3-0.80.4
Condit. Reinf. active minus inactive responses0.91.44.8-2.2-0.4-0.70.72.0-0.50.50.9-1.2
Condit. Reinf. active-inactive response ratio1.62.55.8-2.4-0.1-0.01.32.4-1.21.21.7-1.9
Condit. Reinf. active responses0.71.14.0-2.0-0.5-1.00.21.8-0.20.10.4-0.9
Condit. Reinf. inactive responses0.40.61.3-0.4-0.8-1.1-0.90.10.9-0.9-1.00.5
Condit. Reinf. lever presses0.30.40.8-0.50.50.40.90.8-0.60.50.7-0.7
Condit. Reinf. lever reinforcers received0.50.72.7-1.7-0.4-0.90.21.5-0.0-0.00.2-0.6
Conditioned reinforcement - actives0.20.61.7-1.3-1.3-0.9-0.50.90.4-0.3-0.0-0.3
Conditioned reinforcement - inactives0.10.20.50.4-0.1-0.1-0.7-0.20.4-0.4-0.60.7
Conditioned locomotion0.50.82.4-1.5-0.5-0.10.41.2-0.50.60.9-1.1
Patch foraging indifference point 0 sec0.10.10.5-0.6-0.7-0.4-0.10.40.3-0.20.1-0.0
Patch foraging indifference point AUC0.41.02.2-1.30.50.21.11.5-1.00.81.1-1.2
Delay disc. indifference point, 0s delay0.20.20.91.00.50.40.2-0.60.1-0.2-0.30.6
Delay disc. indifference point, 16s delay1.31.83.50.7-1.1-1.2-0.9-1.11.7-1.5-1.61.9
Delay disc. indifference point, 2s delay0.00.00.10.10.20.20.00.3-0.1-0.1-0.1-0.1
Delay disc. indifference point, 24s delay0.30.41.30.90.5-0.10.4-1.10.4-0.3-0.50.9
Delay disc. indifference point, 4s delay0.40.41.31.1-0.10.2-0.1-0.40.6-0.6-0.70.8
Delay disc. indifference point, 8s delay0.20.30.70.70.1-0.10.1-0.80.5-0.6-0.50.8
Indifference point function ln k0.10.40.70.2-0.8-0.5-0.8-0.60.8-0.6-0.60.7
Indifference point function log k0.10.40.70.2-0.8-0.5-0.8-0.60.8-0.6-0.60.7
Patch foraging total patch changes 0 sec0.00.10.5-0.5-0.7-0.2-0.10.50.2-0.20.10.0
Patch foraging total patch changes 12 sec0.71.01.70.31.11.31.30.6-1.11.01.0-0.7
Patch foraging total patch changes 18 sec0.20.51.7-1.2-0.6-0.2-0.21.3-0.20.20.4-0.7
Patch foraging total patch changes 24 sec0.30.91.5-0.0-1.2-1.0-1.1-0.41.1-1.1-1.00.9
Patch foraging total patch changes 6 sec0.10.10.3-0.6-0.5-0.20.10.60.1-0.20.1-0.1
Patch foraging time to switch 0 sec0.31.34.12.01.51.60.5-1.3-0.60.6-0.00.2
Patch foraging water rate 0 sec0.51.83.9-1.1-2.0-1.9-1.6-0.01.4-1.4-0.90.5
Patch foraging water rate 12 sec0.62.65.9-1.7-2.3-2.4-1.60.41.6-1.5-1.10.6
Patch foraging water rate 18 sec0.10.30.50.7-0.1-0.3-0.3-0.60.6-0.4-0.60.7
Patch foraging water rate 24 sec0.10.10.2-0.0-0.3-0.4-0.50.10.4-0.3-0.30.3
Patch foraging water rate 6 sec1.32.02.90.5-1.4-1.4-1.5-1.51.7-1.6-1.31.4
Seeking ratio, delayed vs. immediate footshock1.21.75.7-2.4-1.7-1.8-1.40.80.5-0.6-0.2-0.6
Distance traveled before self-admin0.51.15.5-2.3-0.6-1.3-0.11.4-0.2-0.20.4-0.8
Distance traveled after self-admin0.71.34.5-2.1-1.3-1.70.11.30.5-0.7-0.1-0.2
Extensor digitorum longus weight0.52.25.4-2.3-2.1-1.9-1.51.50.7-0.7-0.4-0.5
Bone: elastic displacement2.12.78.4-2.9-0.3-0.50.52.1-1.21.21.5-2.3
Bone: elastic work1.01.34.9-2.2-0.5-0.70.41.4-0.60.61.0-1.6
Bone: endosteal estimation0.41.01.8-0.90.40.80.81.1-1.11.11.3-1.3
Bone: endosteal perimeter0.20.40.70.40.70.80.8-0.1-0.60.60.6-0.4
Epididymis fat weight0.10.41.81.30.50.60.5-0.70.1-0.0-0.30.8
Delta time in closed arm before/after self-admin4.34.112.3-2.7-0.10.51.13.5-1.71.62.0-2.4
Delta time in open arm before/after self-admin0.91.13.51.70.10.20.1-1.90.8-0.6-0.81.1
Diff in mean of infusions in LGA sessions0.10.10.20.1-0.2-0.2-0.5-0.50.3-0.4-0.40.4
Delay discount exponential model param0.40.51.4-1.2-0.1-0.1-0.10.6-0.60.60.7-1.1
Extinction: sum of active levers before priming0.00.10.3-0.1-0.30.1-0.50.1-0.20.10.2-0.4
Active lever presses in extinction session 61.31.32.2-0.3-1.2-1.4-1.5-0.61.2-1.4-1.10.8
Bone: final force0.00.00.10.00.10.30.20.2-0.20.10.2-0.2
Bone: final moment0.00.00.0-0.1-0.00.10.10.2-0.1-0.00.1-0.2
Food consumed during 24 hour testing period0.20.40.90.5-0.4-0.40.2-0.40.9-0.9-0.70.9
Glucose0.10.10.5-0.7-0.4-0.40.10.3-0.10.00.2-0.4
Heart weight0.71.23.3-0.5-1.6-1.1-1.8-0.01.1-1.0-0.90.6
Delay discount hyperbolic model param0.40.51.5-1.2-0.2-0.3-0.10.6-0.60.60.7-1.0
Intermittent access intake day 1-15 change0.10.31.0-0.7-1.0-0.5-0.10.80.3-0.10.1-0.4
Intermittent access intake escalation0.00.21.1-0.5-1.0-0.5-0.20.60.4-0.2-0.1-0.2
Intermittent access intake escalation 20.00.10.30.0-0.50.10.10.40.20.00.0-0.1
Intermitt. access day 1 inactive lever presses0.10.92.0-1.4-1.2-1.4-0.90.50.7-0.8-0.50.2
Intermitt. access day 15 inactive lever presses0.10.40.70.1-0.6-0.5-0.8-0.30.7-0.7-0.60.6
Intermitt. access escalation Index0.00.10.20.4-0.2-0.1-0.2-0.30.4-0.4-0.40.5
Intermittent access day 1 total infusions0.10.31.01.00.40.3-0.5-0.60.2-0.3-0.50.8
Intermittent access day 15 total infusions0.10.20.40.4-0.6-0.2-0.6-0.20.6-0.4-0.60.5
Intermittent access terminal intake (last 3 days)0.00.10.4-0.0-0.20.20.10.6-0.10.20.1-0.2
Intermittent access total infusions0.10.10.30.60.10.5-0.20.1-0.00.2-0.10.2
Intermittent access day 1 locomotion0.10.20.70.90.20.6-0.5-0.70.00.1-0.20.5
Intermittent access day 15 total locomotion0.00.10.30.3-0.20.60.10.1-0.00.20.10.0
Intermittent access total locomotion0.10.10.60.6-0.00.8-0.1-0.1-0.20.30.20.0
Intermittent access standard deviation0.31.33.4-0.6-1.8-1.3-1.6-0.51.2-1.0-1.00.5
Left kidney weight1.512.329.6-3.5-5.4-4.9-3.81.13.3-3.3-2.51.0
Right kidney weight1.17.819.1-2.2-4.4-3.8-3.00.52.9-2.8-2.31.2
Cocaine induced anxiety0.10.20.6-0.4-0.8-0.6-0.30.20.4-0.3-0.2-0.1
Post-drug Anxiety0.50.61.2-0.2-1.0-1.0-1.1-0.50.8-0.8-0.80.5
Baseline Anxiety1.42.44.01.3-0.4-0.8-1.8-2.01.4-1.6-1.91.9
Tail length0.00.21.2-0.70.1-0.00.41.1-0.20.10.5-0.2
Length with tail0.10.40.8-0.9-0.8-0.8-0.40.70.5-0.6-0.20.2
Length without tail0.42.44.3-1.0-2.1-2.1-1.7-0.11.7-1.8-1.41.0
Times rat made contact with spout0.20.20.5-0.7-0.4-0.60.30.60.3-0.20.10.0
Lifetime Intake0.10.10.50.70.20.6-0.2-0.0-0.00.2-0.10.3
Liver weight, left0.10.10.3-0.20.4-0.10.60.2-0.30.40.2-0.2
Liver weight, right0.40.61.0-0.50.60.70.90.8-0.81.01.0-0.8
Locomotor activity0.50.81.5-1.2-0.10.10.90.9-0.70.91.1-1.2
Locomotor testing distance0.81.95.2-2.3-0.6-0.30.91.7-1.01.01.4-2.0
Locomotor testing rearing0.62.25.0-2.2-0.20.01.12.2-1.11.31.5-1.9
Locomotion in novel chamber2.93.95.90.0-2.1-2.3-2.1-1.62.2-2.4-2.11.7
Locomotion in novel chamber post-restriction0.30.81.40.3-0.6-1.0-1.2-0.51.0-1.0-1.11.1
Fecal boli incidents, locomotor time 10.00.10.20.4-0.10.1-0.0-0.50.2-0.3-0.10.4
Change in fecal boli incidents, locomotor task0.20.20.50.60.60.70.5-0.1-0.30.40.1-0.0
Time >=10cm from walls, locomotor time 11.41.83.2-1.10.90.81.21.8-1.51.51.5-1.4
Bouts of movement, locomotor time 10.50.62.51.60.91.10.7-0.5-0.1-0.1-0.10.7
Total resting periods, locomotor time 10.70.83.51.90.71.00.4-1.10.1-0.3-0.30.9
Rest time, locomotor task time 10.10.20.60.80.30.60.3-0.7-0.10.10.10.2
Distance moved, locomotor task time 10.10.21.0-0.90.2-0.40.11.0-0.20.00.0-0.4
Vertical activity count, locomotor time 10.10.40.8-0.8-0.6-0.9-0.30.70.5-0.6-0.5-0.0
Time >=10cm from walls, locomotor time 20.20.62.0-1.4-0.2-0.30.31.2-0.50.40.7-0.9
Bouts of movement, locomotor time 20.10.21.2-0.10.50.30.31.1-0.40.20.1-0.3
Total resting periods, locomotor time 20.00.20.80.00.50.30.30.9-0.30.10.0-0.2
Rest time, locomotor task time 20.20.41.91.40.40.60.5-0.70.2-0.1-0.40.6
Distance moved, locomotor task time 20.81.15.0-2.2-0.9-1.3-0.61.30.1-0.30.1-0.7
Vertical activity count, locomotor time 20.51.24.2-2.1-1.4-1.5-0.80.60.5-0.7-0.2-0.4
Light reinforcement 10.10.30.7-0.0-0.6-0.6-0.8-0.60.6-0.5-0.60.4
Light reinforcement 20.51.22.8-0.7-1.4-1.7-1.1-0.11.2-1.1-1.00.7
Bone: marrow area0.41.01.8-0.90.40.80.81.1-1.11.11.3-1.4
Bone: maximum diameter0.20.40.60.1-0.5-0.6-0.7-0.30.7-0.7-0.70.7
Bone: maximum force0.10.20.3-0.60.10.10.40.5-0.30.20.5-0.5
Bone: maximum moment0.10.20.6-0.7-0.1-0.10.30.6-0.30.10.4-0.5
Mean time between licks in bursts0.31.62.60.31.61.51.4-0.3-1.51.41.4-1.2
Mean num. licks in bursts0.20.51.2-1.1-0.3-0.10.81.0-0.40.30.8-0.8
Cd content in liver2.83.15.3-1.70.91.01.32.3-1.92.02.0-2.3
Co content in liver1.61.94.4-2.10.2-0.00.91.9-1.21.11.5-1.8
Cu content in liver2.93.55.9-1.90.60.72.22.4-1.81.82.1-2.4
Fe content in liver0.50.62.2-1.5-1.0-1.0-0.50.90.2-0.30.1-0.5
K content in liver0.30.31.0-0.20.60.11.00.1-0.50.40.5-0.6
Mg content in liver0.50.61.00.3-0.7-0.9-0.2-0.80.9-1.0-0.80.7
Mn content in liver0.20.20.7-0.10.50.40.1-0.0-0.70.50.5-0.8
Na content in liver0.50.51.1-0.70.70.40.80.4-0.90.60.8-1.0
Rb content in liver0.00.00.10.00.0-0.00.30.2-0.10.10.1-0.1
Se content in liver0.81.02.4-1.50.3-0.20.91.3-0.80.91.1-1.1
Sr content in liver0.40.41.0-1.0-0.0-0.0-0.10.7-0.60.60.6-0.9
Zn content in liver0.50.61.10.31.00.91.10.2-0.80.60.6-0.5
Bone: minimum diameter0.30.72.3-1.5-0.6-0.30.41.2-0.30.30.8-0.9
Time in familiar zone, hab. session 10.91.02.1-1.50.5-0.20.71.1-0.91.01.0-1.3
Time in novel zone, hab. session 10.50.61.0-0.20.51.00.70.8-0.80.80.9-0.7
Total zone transitions, hab. session 10.00.00.0-0.00.20.0-0.20.2-0.0-0.1-0.20.1
Total locomotion distance, hab. session 10.30.40.7-0.3-0.7-0.8-0.8-0.10.7-0.8-0.70.5
Locomotion velocity, hab. session 10.60.81.30.7-0.6-0.5-0.9-0.81.0-1.1-1.11.1
Time in familiar zone, hab. session 21.51.72.7-1.60.90.11.51.6-1.21.21.4-1.6
Time in novel zone, hab. session 20.10.10.20.5-0.40.4-0.4-0.30.1-0.1-0.10.2
Total zone transitions, hab. session 20.00.10.2-0.4-0.0-0.30.10.30.1-0.2-0.00.1
Total locomotion distance, hab. session 20.40.51.4-0.4-0.7-1.2-0.6-0.30.8-0.9-0.70.6
Locomotion velocity, hab. session 20.71.02.0-0.2-0.8-1.4-0.9-0.61.1-1.2-1.10.9
Novel to familiar place preference ratio0.30.40.70.2-0.7-0.6-0.3-0.30.9-0.8-0.70.7
Novelty place preference0.20.20.50.3-0.4-0.4-0.1-0.20.7-0.7-0.60.6
Time in novel zone, NPP test0.10.10.20.2-0.3-0.20.00.00.4-0.4-0.40.4
Total zone transitions, NPP test0.40.71.4-0.8-1.2-1.1-1.10.20.7-0.7-0.60.2
Total locomotion distance, NPP test0.81.12.4-0.9-1.3-1.5-1.2-0.01.0-1.1-0.90.5
Locomotion velocity, NPP test1.21.73.7-0.9-1.6-1.9-1.5-0.31.4-1.5-1.30.7
Intraocular pressure0.40.71.01.0-0.6-0.4-0.8-0.80.9-0.8-1.00.9
Delta distance traveled before/after self-admin0.80.91.70.4-1.2-0.8-0.6-0.51.3-1.0-1.01.1
Delta ambulatory time before/after self-admin0.30.61.20.5-1.1-0.6-0.4-0.21.1-0.8-0.80.9
Parametrial fat weight0.20.51.20.8-0.2-0.40.0-0.90.8-1.0-0.71.1
Pavlov. Cond. lever latency1.51.93.10.31.71.61.60.6-1.41.81.4-1.0
Pavlov. Cond. magazine entry latency0.20.30.80.60.60.90.60.0-0.60.40.4-0.3
Pavlov. Cond. change in total contacts0.10.10.40.3-0.0-0.2-0.3-0.20.3-0.7-0.50.4
Pavlov. Cond. index score0.20.30.6-0.1-0.7-0.6-0.6-0.00.5-0.8-0.60.3
Pavlov. Cond. latency score0.40.51.10.1-0.8-0.7-0.8-0.20.7-1.0-0.80.6
Pavlov. Cond. lever contacts1.11.42.4-0.1-1.4-1.4-1.4-0.61.2-1.6-1.20.9
Pavlov. Cond. magazine entry number0.10.20.5-0.5-0.6-0.7-0.3-0.10.4-0.2-0.10.1
Pavlov. Cond. intertrial magazine entries1.21.52.61.0-1.0-0.9-0.8-1.31.5-1.3-1.41.6
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.1-0.8-0.7-0.6-0.10.6-0.9-0.60.4
Pavlov. Cond. response bias0.00.00.1-0.2-0.3-0.2-0.20.10.0-0.3-0.1-0.1
Pavlov. Cond. lever latency0.00.10.4-0.0-0.1-0.1-0.6-0.2-0.00.0-0.1-0.0
Pavlov. Cond. magazine entry latency1.52.24.6-0.81.21.22.21.5-1.51.51.7-1.5
Pavlov. Cond. change in total contacts0.00.10.60.20.50.20.80.0-0.10.10.20.0
Pavlov. Cond. index score0.60.92.8-0.30.90.81.70.8-0.80.81.0-0.8
Pavlov. Cond. latency score0.50.82.7-0.40.80.61.60.9-0.80.70.9-0.7
Pavlov. Cond. lever contacts0.10.10.4-0.30.20.10.70.5-0.20.20.4-0.3
Pavlov. Cond. magazine entry number1.52.05.30.1-1.7-1.4-2.3-1.11.4-1.4-1.41.0
Pavlov. Cond. intertrial magazine entries0.20.31.01.00.10.1-0.6-0.90.4-0.1-0.60.7
Pavlov. Cond. lever-magazine prob. diff.0.71.23.5-0.40.90.91.90.9-1.01.01.2-1.0
Pavlov. Cond. response bias0.40.61.4-0.10.80.71.20.7-0.70.70.8-0.6
Time in closed arm before self-admin0.30.61.91.40.80.50.3-1.40.10.0-0.30.6
Time in closed arm after self-admin0.40.50.9-0.20.30.80.60.9-0.70.90.8-0.6
Time in open arm before self-admin0.70.92.8-1.7-0.4-0.40.31.6-0.60.30.7-1.1
Time in open arm after self-admin0.40.40.70.2-0.7-0.7-0.2-0.60.8-0.8-0.60.5
Bone: periosteal estimation0.10.31.3-1.1-0.8-0.5-0.40.70.1-0.20.1-0.4
Bone: periosteal perimeter0.00.10.2-0.4-0.3-0.5-0.10.20.2-0.3-0.20.0
Bone: post-yield work0.10.10.20.20.40.50.3-0.3-0.20.30.3-0.2
Progressive ratio test 1 active lever presses0.30.51.30.5-0.6-0.3-1.1-0.80.7-0.6-0.70.8
Progressive ratio test 1 breakpoint0.30.51.20.4-0.7-0.3-1.1-0.80.7-0.6-0.70.8
Progressive ratio test 1 inactive lever presses0.10.10.7-0.3-0.4-0.3-0.80.10.2-0.2-0.20.1
Progressive ratio test 2 active lever presses0.10.10.40.1-0.4-0.2-0.7-0.30.3-0.3-0.40.3
Progressive ratio test 2 breakpoint0.10.20.50.2-0.4-0.2-0.7-0.40.4-0.4-0.40.3
Progressive ratio test 2 inactive lever presses0.10.20.50.60.10.1-0.4-0.30.3-0.4-0.50.7
Incentive Sensitization - Responses0.10.41.31.10.10.2-0.3-0.90.4-0.4-0.60.7
Incentive Sensitization - Breakpoint0.10.30.90.90.00.1-0.3-0.80.4-0.4-0.50.6
Sum of active levers in priming session hrs 5-60.50.41.9-1.4-0.4-0.7-0.70.7-0.20.20.2-0.7
Progressive ratio0.51.52.50.9-0.5-1.0-1.1-1.21.3-1.3-1.51.6
Food seeking constrained by brief footshock2.93.65.20.12.32.12.21.6-2.12.12.0-1.5
Seeking ratio, punishment vs. effort3.06.68.7-1.22.12.42.72.7-2.92.82.9-2.8
Retroperitoneal fat weight0.10.63.11.80.60.90.5-0.80.1-0.1-0.30.8
Reaction time number correct0.00.00.1-0.0-0.10.2-0.30.2-0.10.30.2-0.1
Reaction time mean minus median0.00.31.11.00.70.60.6-0.30.1-0.0-0.30.6
Reaction time mean minus median AUC0.00.10.30.40.60.40.50.1-0.20.20.10.1
Reaction time num false alarms0.71.32.10.0-1.0-1.3-0.9-0.91.3-1.4-1.31.2
Reaction time num false alarms AUC0.81.93.0-0.3-1.5-1.7-1.3-0.91.6-1.7-1.41.3
Reaction time trials correct on left0.00.00.1-0.0-0.10.2-0.30.2-0.10.30.2-0.1
Reaction time trials on left0.00.00.10.0-0.10.2-0.20.1-0.10.20.1-0.0
Reaction time mean0.51.24.82.20.90.80.7-1.20.4-0.3-0.71.3
Reaction time mean AUC0.30.83.01.71.00.90.9-0.70.00.1-0.30.8
Median of all reaction times0.91.45.82.40.90.80.5-1.50.5-0.3-0.81.4
Reaction time omissions0.71.13.31.60.20.0-0.0-1.01.1-0.9-1.21.8
Reaction time false alarm rate1.21.73.0-0.4-1.4-1.7-1.1-1.01.5-1.7-1.31.1
Reaction time premature initiation rate0.40.71.6-0.20.60.81.30.1-0.80.91.0-0.9
Reaction time premature initiations0.30.81.3-0.20.71.01.10.2-0.91.11.2-1.0
Std. dev. reaction times0.10.20.80.90.50.50.6-0.20.1-0.1-0.20.5
Reaction time trials completed0.00.00.10.0-0.10.2-0.20.1-0.10.20.1-0.0
Reaction time trials AUC0.00.00.1-0.1-0.30.1-0.40.20.00.10.1-0.0
Run reversals in cocaine runway, females0.91.03.51.90.50.40.1-1.70.5-0.4-0.71.1
Run reversals in cocaine runway, males0.91.02.1-1.4-1.4-1.4-1.01.00.6-0.4-0.4-0.1
Latency to leave start box in cocaine runway0.91.23.30.3-1.1-1.0-1.8-1.11.0-0.9-1.20.8
Latency to leave start box in cocaine runway, F1.92.35.80.2-1.4-1.6-2.4-1.31.5-1.4-1.81.3
Latency to leave start box in cocaine runway, M0.10.10.40.30.20.60.40.1-0.40.40.4-0.3
Std. dev. time between licks in bursts0.71.33.21.31.81.61.0-1.0-1.11.10.7-0.4
Total sessions with >9 infusions0.20.31.41.20.30.9-0.2-0.10.10.1-0.30.6
Short access day 1 total inactive lever presses0.71.52.4-0.4-1.6-1.4-1.5-0.21.4-1.3-1.41.0
Short access day 10 total inactive lever presses0.10.51.6-1.3-0.6-0.9-0.11.20.4-0.5-0.10.1
Short access day 1 total infusions0.20.30.91.0-0.00.3-0.7-0.50.4-0.3-0.60.7
Short access day 10 total infusions0.10.20.40.6-0.20.1-0.6-0.00.3-0.2-0.40.5
Short access total infusions0.20.31.31.20.30.7-0.3-0.30.10.0-0.30.6
Short access day 1 locomotion0.10.20.7-0.2-0.8-0.1-0.30.80.3-0.2-0.10.1
Short access day 10 total locomotion0.31.12.40.8-0.9-0.4-1.0-0.91.3-1.1-1.21.5
Short access total locomotion0.10.20.60.30.30.80.30.5-0.30.50.4-0.1
One hour access (0.3 mA shock)0.50.50.90.00.61.00.50.9-0.80.90.8-0.7
Compulsive drug intake0.20.30.70.70.90.90.4-0.3-0.50.60.4-0.1
One hour access (shock baseline)0.10.30.9-0.7-0.9-0.6-0.60.60.4-0.4-0.40.0
Social response proportion0.20.30.80.50.90.60.7-0.1-0.30.40.2-0.1
Social responses0.91.22.80.11.71.01.40.3-1.21.21.1-0.9
Social time0.10.20.8-0.9-0.2-0.8-0.00.30.2-0.00.1-0.1
Soleus weight1.44.09.8-2.5-3.1-3.0-2.00.81.6-1.7-1.0-0.0
Bone: stiffness0.00.10.30.60.20.3-0.1-0.20.1-0.2-0.20.4
Tibialis anterior weight2.27.615.1-1.8-3.9-3.6-3.60.32.8-2.8-2.51.6
Time to tail flick, vehicle, before self-admin1.72.14.00.4-1.6-1.2-2.0-1.41.6-1.5-1.61.3
Time to tail flick, vehicle, after self-admin1.02.03.80.9-1.0-1.1-2.0-1.81.5-1.2-1.61.4
Time to tail flick, test, before self-admin1.01.13.8-0.2-2.0-1.2-1.2-0.51.1-0.8-0.80.4
Time to tail flick, test, after self-admin1.01.11.8-0.4-1.2-1.3-1.3-0.71.1-1.1-1.10.7
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.2-0.2-0.9-0.6-0.40.5-0.4-0.60.4
Delta time to tail flick, test, before/after SA0.10.20.40.30.5-0.1-0.3-0.60.2-0.5-0.50.6
Tibia length0.30.81.11.0-0.9-0.2-0.9-1.00.9-0.9-0.91.0
Ambulatory time before self-admin0.51.46.6-2.6-0.4-1.1-0.01.5-0.50.10.7-1.2
Ambulatory time after self-admin0.50.72.9-1.7-1.0-1.1-0.11.10.2-0.30.2-0.4
Bone: tissue strength1.61.72.8-0.81.01.01.71.1-1.41.41.5-1.5
Total heroin consumption0.20.20.70.80.60.5-0.3-0.6-0.20.1-0.10.1
Bone: trabecular number1.22.33.1-1.21.11.01.51.7-1.61.71.7-1.8
Bone: trabecular spacing2.02.94.30.7-1.4-1.6-2.0-1.51.9-2.0-2.11.8
Bone: trabecular thickness0.91.21.8-0.81.00.71.41.0-1.21.01.3-1.2
Bone: trabecular tissue density0.00.10.2-0.30.4-0.20.30.4-0.2-0.0-0.1-0.0
Water consumed over 24 hours0.71.44.6-2.1-0.9-0.70.42.1-0.30.30.9-1.1
Number of responses in last shaping day0.91.22.8-1.4-1.7-1.6-1.00.40.8-0.9-0.6-0.0