Hub : Genes

Nck2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Nck2 0.82 0.07 0.0e+00 0.37 0.39 0.38 0.37 9.2e-43 8.7e-46 1.1e-44 3.6e-43
2 Brain gene expression Nck2 0.27 0.16 3.6e-07 0.06 0.07 0.06 0.03 4.1e-06 1.6e-07 1.2e-06 3.5e-04
3 IL mRNA stability Nck2 0.22 0.14 1.1e-03 0.11 0.09 0.09 0.08 1.7e-03 3.7e-03 4.1e-03 5.7e-03
4 Brain isoform ratio XM_006244825.4 0.14 0.12 2.4e-06 0.07 0.06 0.06 0.02 2.0e-07 3.2e-06 2.0e-06 8.4e-03
5 Brain mRNA stability Nck2 0.09 0.06 4.4e-08 0.09 0.06 0.07 0.07 1.6e-08 4.6e-06 8.5e-07 4.0e-07
6 Liver mRNA stability Nck2 0.32 0.16 3.3e-13 0.08 0.08 0.08 0.08 1.5e-09 1.4e-09 8.2e-09 2.1e-09
7 BLA mRNA stability Nck2 0.12 0.09 1.4e-04 0.08 0.07 0.07 0.05 4.1e-05 7.8e-05 2.1e-04 1.7e-03
8 Liver alternative TSS XM_006244825.4 0.11 0.07 8.2e-06 0.04 0.03 0.03 0.03 7.5e-05 1.3e-04 1.6e-04 1.8e-04
9 IL intron excision ratio chr9_45803030_45824030 0.18 0.12 4.8e-03 -0.01 0.04 0.02 -0 7.2e-01 4.0e-02 1.3e-01 4.4e-01
10 Liver alternative TSS NM_001108216.1 0.1 0.07 3.7e-05 0.03 0.03 0.03 0.03 1.7e-04 3.8e-04 5.9e-04 5.0e-04
11 Adipose gene expression Nck2 0.05 0.03 2.3e-06 0.03 0.03 0.02 0.03 1.0e-04 1.5e-04 9.2e-04 1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density4.06.79.2-2.02.52.9-2.93.0-2.02.9-2.03.02.0-2.9
Area under the delay curve0.50.51.2-0.70.4-0.30.4-0.5-0.8-0.4-1.1-0.71.10.8
BMI with tail2.27.010.12.8-3.2-3.03.0-2.81.9-3.11.8-2.7-1.82.5
BMI without tail0.10.20.7-0.80.5-0.1-0.30.2-0.50.3-0.60.20.5-0.1
Body weight0.10.41.11.0-1.0-0.70.8-0.60.2-0.70.3-0.3-0.30.1
Weight adjusted by age1.61.84.41.6-1.3-1.20.5-1.01.9-0.32.1-0.7-2.10.6
Bone surface0.30.51.1-0.30.40.7-0.70.8-0.70.7-0.70.90.7-1.0
Bone volume1.83.04.4-1.21.51.9-1.92.0-1.51.8-1.42.11.5-2.1
Breakpoint value in progressive ratio session0.80.92.1-1.10.50.5-0.50.7-1.40.5-1.30.81.2-0.9
Number of licking bursts0.40.51.7-1.31.10.4-0.60.2-0.60.6-0.60.20.6-0.0
Context. condit. distance diff. score1.01.23.0-0.10.81.3-1.31.7-0.71.1-0.61.40.7-1.4
Locomotion velocity, session 10.00.00.0-0.1-0.1-0.10.1-0.1-0.2-0.2-0.1-0.10.10.1
Locomotion distance, session 11.21.62.61.6-1.4-1.21.1-1.01.4-1.11.5-1.0-1.50.9
Locomotion velocity, session 23.74.35.21.7-2.2-2.22.2-2.31.9-2.12.0-2.2-2.02.1
Locomotion distance, session 23.24.47.02.0-2.2-2.62.3-2.61.5-2.31.5-2.1-1.52.0
Locomotion velocity, session 30.10.10.4-0.20.20.4-0.40.60.10.40.10.4-0.1-0.4
Locomotion distance, session 30.10.10.4-0.30.10.3-0.30.6-0.30.2-0.30.40.2-0.3
Stereotopy head waving bouts, day 30.30.40.6-0.50.80.6-0.50.5-0.50.7-0.60.50.7-0.6
Stereotopy head waving duration, day 30.20.20.6-0.50.80.4-0.40.2-0.40.6-0.50.30.6-0.2
Locomotion velocity, session 71.61.74.81.6-0.8-0.50.5-0.62.2-0.62.0-0.9-2.01.0
Locomotion distance, session 70.91.11.61.3-0.9-1.10.9-0.71.2-0.91.0-1.1-1.01.1
Stereotopy head waving bouts, day 70.10.10.2-0.20.40.3-0.30.4-0.30.4-0.40.30.4-0.3
Stereotopy head waving duration, day 70.10.20.30.30.20.5-0.50.60.10.50.20.6-0.2-0.6
Locomotion velocity, session 80.30.41.30.7-0.80.0-0.00.00.7-0.01.20.3-1.2-0.3
Locomotion distance, session 80.81.23.31.8-1.7-1.00.8-0.50.9-1.01.3-0.4-1.30.2
Degree of sensitization distance1.41.42.31.1-0.8-1.41.2-1.31.0-1.20.7-1.5-0.71.5
Degree of sensitization stereotypy0.10.10.30.3-0.20.2-0.20.4-0.10.20.00.40.0-0.5
Conditioned locomotion0.91.13.7-1.0-0.20.3-0.10.7-1.90.1-1.40.91.5-1.1
Cocaine response after cond. corrected0.50.60.9-0.4-0.5-0.81.0-0.6-0.6-1.0-0.6-0.90.70.9
Cocaine response after cond. not corrected0.40.40.8-0.1-0.6-0.70.9-0.6-0.3-0.9-0.3-0.80.40.7
Cocaine response before conditioning0.30.31.10.8-0.40.1-0.10.10.90.11.00.2-1.1-0.1
Saline control response0.50.61.51.2-1.1-0.20.4-0.00.8-0.41.1-0.2-1.20.1
Bone: connectivity density0.91.51.8-1.11.11.2-1.21.2-1.21.2-1.21.41.2-1.4
Bone: cortical apparent density4.05.29.02.6-2.3-1.71.8-2.02.8-1.83.0-1.9-2.91.7
Bone: cortical area0.20.31.00.7-1.0-0.40.5-0.40.1-0.60.3-0.1-0.4-0.1
Bone: cortical porosity1.01.11.7-1.01.31.1-1.31.1-0.71.2-0.71.10.8-1.0
Bone: cortical porosity1.21.32.1-0.81.31.4-1.51.4-0.61.4-0.61.30.6-1.2
Bone: cortical thickness0.30.41.70.7-1.3-0.60.7-0.60.1-0.70.6-0.2-0.6-0.1
Bone: cortical thickness0.10.10.40.5-0.6-0.20.3-0.3-0.2-0.30.00.0-0.1-0.2
Bone: cortical tissue density3.85.08.82.6-2.2-1.71.7-2.02.8-1.73.0-1.8-2.81.7
Condit. Reinf. active minus inactive responses0.10.20.2-0.10.0-0.40.4-0.4-0.4-0.4-0.4-0.50.50.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.40.20.00.10.0-0.7-0.2-0.6-0.10.70.2
Condit. Reinf. active responses0.10.10.20.3-0.1-0.50.3-0.3-0.0-0.4-0.1-0.40.10.4
Condit. Reinf. inactive responses0.60.71.01.0-0.7-1.00.6-0.50.9-0.80.7-0.9-0.80.9
Incentive salience index mean0.00.00.1-0.00.10.00.0-0.1-0.3-0.0-0.20.00.3-0.1
Condit. Reinf. lever presses0.20.30.80.20.30.8-0.70.5-0.10.70.10.8-0.0-0.9
Condit. Reinf. active minus inactive responses0.81.02.0-1.41.20.9-0.81.0-1.00.9-1.20.61.1-0.5
Condit. Reinf. active-inactive response ratio2.12.23.0-1.71.41.5-1.21.6-1.71.3-1.61.31.5-1.4
Condit. Reinf. active responses0.10.10.3-0.50.3-0.30.2-0.1-0.4-0.1-0.6-0.30.50.3
Condit. Reinf. inactive responses1.21.41.91.2-0.9-1.41.0-1.41.4-1.01.1-1.3-1.21.3
Condit. Reinf. lever presses0.30.41.0-0.71.00.7-0.80.9-0.30.7-0.60.50.5-0.3
Condit. Reinf. lever reinforcers received0.10.20.3-0.50.2-0.50.4-0.3-0.3-0.3-0.5-0.60.40.5
Conditioned reinforcement - actives0.30.31.0-0.71.00.5-0.60.2-0.30.3-0.8-0.00.60.2
Conditioned reinforcement - inactives0.30.30.7-0.10.60.8-0.60.7-0.30.5-0.50.60.4-0.6
Conditioned locomotion0.91.04.42.1-1.4-0.81.1-0.80.6-1.20.1-0.7-0.30.4
Patch foraging indifference point 0 sec0.71.12.71.5-0.9-0.40.6-0.31.6-0.51.6-0.5-1.60.7
Patch foraging indifference point AUC0.80.91.91.0-1.3-1.21.4-1.00.1-1.20.2-1.0-0.10.6
Delay disc. indifference point, 0s delay0.70.71.41.0-0.7-0.70.5-0.71.2-0.51.2-0.7-1.20.6
Delay disc. indifference point, 16s delay1.21.23.3-1.31.10.6-0.50.5-1.50.4-1.80.31.8-0.3
Delay disc. indifference point, 2s delay0.20.20.40.3-0.1-0.30.5-0.4-0.3-0.5-0.6-0.60.60.5
Delay disc. indifference point, 24s delay0.20.20.7-0.60.80.5-0.50.3-0.20.4-0.40.10.40.1
Delay disc. indifference point, 4s delay0.50.51.01.0-0.7-0.80.8-0.80.4-0.80.2-0.8-0.20.8
Delay disc. indifference point, 8s delay0.30.30.9-0.90.60.10.1-0.3-0.6-0.1-0.8-0.50.80.6
Indifference point function ln k0.60.92.1-0.2-0.1-0.80.4-1.11.3-0.41.1-1.1-1.11.4
Indifference point function log k0.60.92.1-0.2-0.1-0.80.4-1.11.3-0.41.1-1.1-1.11.4
Patch foraging total patch changes 0 sec0.71.12.61.6-1.1-0.60.9-0.51.4-0.81.3-0.7-1.30.8
Patch foraging total patch changes 12 sec0.30.41.41.2-0.90.40.30.60.4-0.20.60.3-0.6-0.5
Patch foraging total patch changes 18 sec1.11.42.61.2-1.5-1.41.6-1.00.8-1.50.7-1.2-0.81.1
Patch foraging total patch changes 24 sec0.70.83.61.9-1.2-0.20.8-0.11.1-0.70.9-0.3-1.00.1
Patch foraging total patch changes 6 sec0.30.41.91.4-0.2-0.20.20.11.1-0.10.7-0.2-0.60.2
Patch foraging time to switch 0 sec0.60.91.6-0.80.91.2-1.21.3-0.51.0-0.41.20.3-1.0
Patch foraging water rate 0 sec0.50.81.70.2-0.8-1.31.2-1.1-0.2-1.2-0.2-1.00.30.9
Patch foraging water rate 12 sec0.10.20.6-0.10.3-0.50.2-0.40.4-0.20.1-0.6-0.10.7
Patch foraging water rate 18 sec0.30.41.4-0.81.20.6-0.80.20.20.90.10.2-0.00.1
Patch foraging water rate 24 sec0.10.20.40.10.4-0.3-0.1-0.60.60.00.2-0.5-0.30.7
Patch foraging water rate 6 sec0.20.31.2-0.60.8-0.30.0-0.70.50.00.3-0.8-0.11.1
Seeking ratio, delayed vs. immediate footshock0.70.81.9-0.3-0.10.8-0.70.9-1.30.5-0.91.10.9-1.4
Distance traveled before self-admin0.20.20.7-0.10.20.2-0.40.3-0.60.4-0.60.70.6-0.8
Distance traveled after self-admin2.42.75.6-0.61.11.9-1.92.0-0.92.0-0.72.30.6-2.4
Extensor digitorum longus weight7.629.832.95.7-5.0-5.55.1-5.65.7-5.25.5-5.6-5.55.5
Bone: elastic displacement1.01.23.5-1.91.40.7-0.80.4-1.20.8-1.30.61.3-0.4
Bone: elastic work0.70.91.4-1.10.70.8-0.70.7-1.20.8-1.01.01.1-1.0
Bone: endosteal estimation0.10.10.4-0.00.10.1-0.10.4-0.50.1-0.60.20.6-0.3
Bone: endosteal perimeter0.00.10.2-0.10.00.10.00.2-0.40.1-0.40.20.4-0.3
Epididymis fat weight0.00.10.3-0.20.2-0.1-0.0-0.60.3-0.00.0-0.2-0.20.2
Delta time in closed arm before/after self-admin0.40.41.6-0.81.20.4-0.80.40.40.70.00.2-0.00.1
Delta time in open arm before/after self-admin0.20.10.20.40.10.0-0.40.1-0.50.4-0.50.40.5-0.5
Diff in mean of infusions in LGA sessions1.41.52.7-1.51.30.4-1.01.0-1.61.0-1.51.11.5-1.2
Delay discount exponential model param0.50.51.60.7-0.50.2-0.30.50.90.31.30.6-1.3-0.6
Extinction: sum of active levers before priming1.81.85.6-0.6-0.40.40.20.9-2.40.1-2.01.22.0-1.8
Active lever presses in extinction session 60.80.81.70.0-0.7-1.01.3-0.9-0.9-1.1-1.0-0.81.00.5
Bone: final force0.30.51.81.3-1.3-0.40.6-0.20.4-0.60.7-0.1-0.8-0.1
Bone: final moment0.30.51.61.3-1.3-0.40.6-0.30.4-0.70.7-0.1-0.8-0.0
Food consumed during 24 hour testing period0.50.61.20.7-1.0-0.81.1-0.70.2-1.00.2-0.9-0.20.7
Glucose0.30.51.2-1.10.30.5-0.10.6-1.10.1-0.90.41.0-0.4
Heart weight0.40.61.70.4-0.3-0.90.8-1.30.5-0.90.5-1.0-0.41.0
Delay discount hyperbolic model param0.40.50.90.3-0.20.5-0.60.80.50.60.90.9-0.9-0.9
Intermittent access intake day 1-15 change0.30.30.8-0.70.80.8-0.90.60.10.60.20.3-0.2-0.1
Intermittent access intake escalation0.80.81.4-1.21.01.2-1.20.9-0.41.1-0.10.80.1-0.6
Intermittent access intake escalation 21.11.12.5-1.61.50.9-1.50.9-0.61.3-0.50.90.4-0.6
Intermitt. access day 1 inactive lever presses0.50.51.50.4-0.31.2-0.20.9-0.70.3-0.40.90.4-1.2
Intermitt. access day 15 inactive lever presses0.40.51.60.40.51.3-0.90.70.50.50.50.6-0.5-0.5
Intermitt. access escalation Index0.10.10.40.6-0.0-0.60.0-0.30.2-0.1-0.0-0.00.00.0
Intermittent access day 1 total infusions0.70.93.2-0.70.50.40.1-0.0-1.5-0.3-1.80.01.7-0.1
Intermittent access day 15 total infusions1.21.32.5-1.51.61.2-1.00.8-1.20.8-1.40.61.4-0.5
Intermittent access terminal intake (last 3 days)0.60.71.8-1.01.10.4-0.60.1-1.10.3-1.30.31.2-0.2
Intermittent access total infusions1.01.12.7-1.41.21.0-0.50.4-1.40.3-1.60.31.6-0.2
Intermittent access day 1 locomotion0.10.10.30.4-0.10.10.2-0.1-0.4-0.2-0.60.00.5-0.2
Intermittent access day 15 total locomotion0.00.00.2-0.50.10.30.00.1-0.1-0.2-0.2-0.10.00.2
Intermittent access total locomotion0.00.10.1-0.30.00.30.2-0.2-0.1-0.3-0.3-0.20.10.3
Intermittent access standard deviation2.02.14.6-0.90.71.2-0.91.2-2.20.8-2.01.42.0-1.7
Left kidney weight0.00.10.30.10.30.0-0.2-0.30.60.20.60.0-0.50.0
Right kidney weight0.20.71.81.4-0.90.3-0.10.20.80.21.20.6-1.2-0.9
Cocaine induced anxiety2.63.05.22.1-1.7-1.61.3-1.32.3-1.32.1-1.4-2.11.4
Post-drug Anxiety1.92.23.91.9-2.0-1.51.8-1.41.0-1.81.0-1.3-0.91.1
Baseline Anxiety1.21.34.1-1.00.40.7-0.10.3-2.0-0.1-1.90.41.9-0.6
Tail length1.44.17.4-2.72.31.7-2.11.8-2.02.2-1.91.91.8-1.7
Length with tail0.31.11.9-0.71.01.1-1.21.1-0.81.2-0.61.30.6-1.4
Length without tail1.53.28.02.8-2.4-1.41.7-1.21.7-1.81.9-1.2-1.80.8
Times rat made contact with spout1.51.73.7-1.91.50.9-0.70.6-1.70.8-1.90.61.9-0.4
Lifetime Intake0.60.61.8-1.00.80.7-0.10.1-1.0-0.0-1.3-0.01.30.0
Liver weight, left0.10.10.30.20.40.4-0.60.20.00.5-0.10.50.1-0.6
Liver weight, right0.20.40.7-0.70.40.5-0.40.8-0.70.6-0.70.60.6-0.6
Locomotor activity0.20.30.6-0.30.80.3-0.60.5-0.50.7-0.60.50.7-0.4
Locomotor testing distance1.21.93.0-0.81.61.3-1.71.7-0.91.7-1.11.51.1-1.4
Locomotor testing rearing1.82.86.2-1.01.72.1-2.12.5-0.82.0-0.81.80.7-1.6
Locomotion in novel chamber5.87.29.52.8-3.0-2.93.0-2.92.1-3.12.0-2.8-2.12.6
Locomotion in novel chamber post-restriction2.63.25.42.1-2.3-2.22.1-1.81.1-2.11.1-1.7-1.11.3
Fecal boli incidents, locomotor time 11.61.73.20.7-1.5-1.21.8-1.40.6-1.80.6-1.6-0.61.6
Change in fecal boli incidents, locomotor task0.30.30.6-0.20.10.5-0.30.6-0.70.3-0.60.60.6-0.8
Time >=10cm from walls, locomotor time 13.03.05.70.7-0.9-1.51.3-1.72.2-1.42.0-2.1-2.02.4
Bouts of movement, locomotor time 15.96.411.31.3-2.5-3.23.4-2.81.0-3.20.7-3.3-0.73.2
Total resting periods, locomotor time 16.26.811.51.6-2.7-3.23.4-2.81.2-3.31.0-3.2-1.03.1
Rest time, locomotor task time 10.80.92.3-0.3-0.5-0.51.0-0.5-1.3-1.0-1.5-0.61.50.3
Distance moved, locomotor task time 10.30.30.8-0.30.7-0.1-0.4-0.30.90.40.8-0.1-0.80.5
Vertical activity count, locomotor time 10.80.81.6-0.70.91.0-1.30.80.51.20.71.0-0.7-0.7
Time >=10cm from walls, locomotor time 20.10.10.4-0.70.10.1-0.10.1-0.3-0.0-0.2-0.00.20.0
Bouts of movement, locomotor time 21.92.13.61.5-1.7-1.61.8-1.60.7-1.90.6-1.5-0.61.3
Total resting periods, locomotor time 21.71.83.21.5-1.6-1.51.8-1.50.6-1.80.5-1.4-0.51.2
Rest time, locomotor task time 20.20.30.8-0.60.40.9-0.20.5-0.50.2-0.60.20.6-0.2
Distance moved, locomotor task time 20.70.81.70.2-0.3-1.20.5-1.21.0-0.60.9-1.0-0.91.3
Vertical activity count, locomotor time 20.60.61.10.8-1.0-0.90.5-0.80.7-0.61.0-0.4-1.00.4
Light reinforcement 13.76.715.33.9-3.2-2.32.8-1.82.3-2.82.2-2.4-2.22.0
Light reinforcement 21.11.54.32.1-1.7-1.11.5-0.70.8-1.40.7-1.1-0.70.8
Bone: marrow area0.00.10.30.00.10.0-0.10.4-0.40.0-0.60.20.5-0.3
Bone: maximum diameter0.10.10.4-0.1-0.00.3-0.30.3-0.50.2-0.40.50.4-0.7
Bone: maximum force0.30.51.81.3-1.3-0.40.6-0.20.3-0.70.5-0.1-0.6-0.1
Bone: maximum moment0.30.51.71.3-1.2-0.50.6-0.30.4-0.70.5-0.2-0.6-0.0
Mean time between licks in bursts1.41.92.61.3-1.3-1.31.3-1.41.6-1.31.5-1.3-1.51.4
Mean num. licks in bursts0.10.20.40.5-0.6-0.30.6-0.3-0.1-0.6-0.2-0.40.20.2
Cd content in liver0.10.20.4-0.1-0.00.4-0.30.6-0.30.3-0.30.50.4-0.6
Co content in liver0.40.50.8-0.70.80.8-0.70.9-0.70.7-0.70.60.7-0.5
Cu content in liver0.50.61.0-0.50.91.0-0.91.0-0.70.8-0.80.80.7-0.7
Fe content in liver2.83.45.4-1.41.32.2-1.82.1-1.71.9-1.52.31.5-2.3
K content in liver1.51.52.31.5-1.4-1.11.1-1.01.3-1.11.5-0.9-1.50.8
Mg content in liver0.40.41.00.9-0.8-0.30.4-0.30.8-0.40.9-0.3-1.00.1
Mn content in liver0.70.82.01.1-0.8-0.70.5-0.61.2-0.51.3-0.6-1.40.5
Na content in liver0.50.51.10.00.51.0-1.00.60.21.00.21.0-0.2-1.0
Rb content in liver2.63.24.21.9-2.0-2.02.0-1.91.2-2.01.4-1.8-1.41.6
Se content in liver0.20.20.70.4-0.8-0.40.6-0.2-0.0-0.60.2-0.3-0.30.2
Sr content in liver0.20.20.5-0.30.7-0.30.1-0.30.1-0.1-0.4-0.50.50.7
Zn content in liver0.10.10.2-0.40.20.4-0.10.40.00.1-0.0-0.00.00.2
Bone: minimum diameter0.50.92.41.5-1.3-1.00.9-0.90.7-1.00.7-0.6-0.70.4
Time in familiar zone, hab. session 10.90.82.7-1.00.4-0.00.00.2-1.6-0.0-1.60.31.7-0.4
Time in novel zone, hab. session 10.70.61.2-1.01.10.9-1.00.7-0.41.0-0.40.70.4-0.5
Total zone transitions, hab. session 10.50.62.00.8-0.20.3-0.30.21.40.41.40.3-1.4-0.2
Total locomotion distance, hab. session 10.91.21.51.0-1.2-1.11.1-1.21.2-1.01.2-1.0-1.21.0
Locomotion velocity, hab. session 10.91.32.11.2-1.3-0.91.0-0.91.4-0.91.4-0.9-1.50.8
Time in familiar zone, hab. session 20.60.60.9-1.01.00.9-0.80.9-0.70.8-0.70.60.8-0.5
Time in novel zone, hab. session 20.10.10.20.4-0.3-0.30.2-0.30.0-0.30.0-0.1-0.0-0.0
Total zone transitions, hab. session 20.20.30.70.5-0.8-0.70.7-0.60.2-0.70.3-0.4-0.30.3
Total locomotion distance, hab. session 21.11.42.50.6-0.9-1.51.5-1.50.8-1.40.5-1.6-0.61.6
Locomotion velocity, hab. session 21.01.42.10.7-1.0-1.41.4-1.40.9-1.30.8-1.4-0.81.4
Novel to familiar place preference ratio0.60.72.0-1.10.3-0.30.3-0.1-1.4-0.3-1.4-0.21.40.1
Novelty place preference0.70.72.0-1.20.4-0.20.20.0-1.4-0.2-1.4-0.11.40.1
Time in novel zone, NPP test0.91.02.8-1.40.6-0.0-0.00.3-1.6-0.0-1.60.11.7-0.1
Total zone transitions, NPP test0.40.61.00.4-0.8-0.90.7-0.90.8-0.60.9-0.7-1.00.8
Total locomotion distance, NPP test0.71.01.80.3-0.7-1.11.0-1.21.0-1.00.8-1.2-0.91.3
Locomotion velocity, NPP test1.31.82.50.8-1.0-1.41.3-1.51.5-1.21.4-1.5-1.51.6
Intraocular pressure1.52.13.61.1-1.7-1.51.9-1.60.9-1.80.9-1.6-1.01.5
Delta distance traveled before/after self-admin0.40.51.4-0.30.41.2-0.80.90.20.90.40.7-0.4-0.7
Delta ambulatory time before/after self-admin0.30.41.1-0.10.41.1-0.70.80.30.70.30.6-0.3-0.5
Parametrial fat weight0.10.20.70.7-0.6-0.80.3-0.7-0.3-0.4-0.1-0.00.2-0.1
Pavlov. Cond. lever latency0.30.41.30.1-0.2-0.70.6-0.50.4-0.70.0-1.0-0.11.1
Pavlov. Cond. magazine entry latency0.00.10.20.10.20.3-0.40.2-0.10.3-0.10.40.1-0.4
Pavlov. Cond. change in total contacts0.10.10.30.2-0.6-0.30.5-0.2-0.3-0.5-0.1-0.30.20.1
Pavlov. Cond. index score0.30.30.7-0.40.30.6-0.50.3-0.80.5-0.50.80.6-0.8
Pavlov. Cond. latency score0.30.41.0-0.40.40.7-0.60.4-0.70.6-0.50.90.6-1.0
Pavlov. Cond. lever contacts0.20.20.7-0.10.00.5-0.40.2-0.30.4-0.10.70.1-0.8
Pavlov. Cond. magazine entry number0.70.91.10.8-1.0-1.01.0-0.90.9-1.00.9-1.0-0.91.0
Pavlov. Cond. intertrial magazine entries0.30.30.6-0.2-0.3-0.70.7-0.7-0.2-0.7-0.2-0.70.20.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.2-0.00.1-0.1-0.0-0.60.1-0.40.40.4-0.5
Pavlov. Cond. response bias0.10.10.4-0.20.10.4-0.30.2-0.50.3-0.30.50.3-0.7
Pavlov. Cond. lever latency0.30.51.00.3-1.0-0.71.0-0.80.1-0.90.3-0.7-0.20.5
Pavlov. Cond. magazine entry latency0.60.61.20.70.40.8-1.01.10.90.90.80.7-0.8-0.7
Pavlov. Cond. change in total contacts0.50.71.1-0.91.10.8-0.91.1-0.60.9-0.70.70.7-0.5
Pavlov. Cond. index score0.30.41.2-0.10.70.7-0.91.1-0.10.8-0.20.80.2-0.7
Pavlov. Cond. latency score0.20.30.8-0.00.60.5-0.80.90.10.7-0.10.60.0-0.5
Pavlov. Cond. lever contacts0.91.32.8-0.71.71.2-1.61.3-0.21.5-0.61.10.5-0.8
Pavlov. Cond. magazine entry number0.80.92.20.0-1.0-1.21.3-1.5-0.4-1.3-0.1-1.00.10.9
Pavlov. Cond. intertrial magazine entries2.83.65.31.5-2.0-2.22.3-2.31.1-2.31.2-2.2-1.22.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.80.10.50.5-0.80.90.20.70.00.6-0.1-0.5
Pavlov. Cond. response bias1.11.53.4-0.21.51.4-1.91.60.31.80.01.3-0.1-1.1
Time in closed arm before self-admin0.80.93.5-1.1-0.1-0.00.20.2-1.9-0.3-1.60.31.6-0.5
Time in closed arm after self-admin0.70.81.0-1.00.70.8-0.81.0-0.90.7-0.80.90.8-1.0
Time in open arm before self-admin0.50.50.80.4-0.4-0.70.6-0.80.9-0.70.8-0.8-0.80.9
Time in open arm after self-admin0.20.20.5-0.20.50.4-0.70.4-0.30.7-0.20.60.2-0.6
Bone: periosteal estimation0.10.10.30.2-0.30.1-0.00.3-0.5-0.0-0.40.40.3-0.5
Bone: periosteal perimeter0.10.10.5-0.2-0.2-0.00.20.1-0.7-0.1-0.60.20.6-0.3
Bone: post-yield work0.20.30.91.0-0.10.4-0.50.50.50.40.60.6-0.6-0.7
Progressive ratio test 1 active lever presses0.40.40.80.7-0.3-0.70.7-0.90.2-0.9-0.2-0.80.20.7
Progressive ratio test 1 breakpoint0.40.40.80.8-0.3-0.80.7-0.90.0-0.9-0.3-0.70.30.6
Progressive ratio test 1 inactive lever presses0.40.41.21.1-0.30.8-0.30.7-0.40.1-0.50.80.3-1.1
Progressive ratio test 2 active lever presses0.20.20.8-0.90.80.5-0.60.10.10.5-0.10.1-0.00.1
Progressive ratio test 2 breakpoint0.10.10.3-0.50.60.2-0.3-0.20.40.10.1-0.3-0.20.5
Progressive ratio test 2 inactive lever presses0.50.61.4-0.10.61.2-1.01.0-0.10.8-0.20.90.0-0.9
Incentive Sensitization - Responses0.70.71.5-1.11.01.0-1.20.60.61.10.60.5-0.7-0.1
Incentive Sensitization - Breakpoint0.60.61.2-0.90.80.9-1.10.50.70.90.80.4-0.9-0.0
Sum of active levers in priming session hrs 5-61.61.64.1-2.01.20.2-0.40.3-1.80.6-1.90.51.9-0.3
Progressive ratio1.51.83.4-0.3-1.2-1.81.8-1.9-0.1-1.70.1-1.6-0.11.6
Food seeking constrained by brief footshock0.10.10.2-0.30.00.00.0-0.00.30.00.4-0.3-0.40.4
Seeking ratio, punishment vs. effort0.80.92.00.30.91.3-1.31.40.21.2-0.01.10.1-1.1
Retroperitoneal fat weight0.51.56.52.5-1.5-1.00.9-1.01.2-0.91.1-0.7-1.00.3
Reaction time number correct1.21.72.61.4-1.2-1.21.2-1.61.4-1.31.2-1.4-1.21.3
Reaction time mean minus median1.82.44.4-2.11.81.5-1.61.8-1.31.6-1.21.31.2-1.1
Reaction time mean minus median AUC1.62.13.5-1.91.81.4-1.71.8-1.11.5-1.01.21.0-1.0
Reaction time num false alarms2.02.74.32.1-1.7-1.81.6-1.71.5-1.51.3-1.6-1.51.5
Reaction time num false alarms AUC2.94.06.62.6-2.0-2.11.9-2.01.9-1.91.7-1.9-1.91.8
Reaction time trials correct on left1.21.72.61.4-1.2-1.21.2-1.61.4-1.31.2-1.4-1.21.3
Reaction time trials on left1.11.62.41.3-1.1-1.21.1-1.51.3-1.21.2-1.3-1.21.3
Reaction time mean2.83.95.6-2.42.21.9-2.01.9-2.01.8-2.11.82.0-1.6
Reaction time mean AUC2.12.93.9-2.01.91.6-1.71.5-1.81.5-2.01.51.8-1.3
Median of all reaction times2.33.24.6-2.01.91.7-1.71.6-2.01.4-2.11.62.0-1.5
Reaction time omissions1.31.84.1-2.01.31.5-1.31.6-1.21.1-1.11.21.0-1.0
Reaction time false alarm rate0.91.22.31.5-1.1-1.11.0-1.01.1-0.91.1-1.0-1.20.9
Reaction time premature initiation rate0.10.20.40.30.10.5-0.40.7-0.20.30.00.50.2-0.6
Reaction time premature initiations0.20.21.11.1-0.5-0.10.2-0.20.4-0.40.6-0.2-0.40.0
Std. dev. reaction times2.73.87.5-2.72.42.0-2.22.1-1.52.1-1.51.71.4-1.4
Reaction time trials completed1.11.62.41.3-1.1-1.21.1-1.51.3-1.21.2-1.3-1.21.3
Reaction time trials AUC1.01.52.21.3-1.1-1.11.1-1.51.3-1.21.1-1.3-1.11.2
Run reversals in cocaine runway, females1.01.01.91.2-0.9-0.60.7-0.81.4-0.71.4-0.8-1.40.7
Run reversals in cocaine runway, males0.20.20.50.4-0.7-0.50.7-0.3-0.3-0.6-0.2-0.30.30.0
Latency to leave start box in cocaine runway2.73.05.62.4-2.4-1.61.6-1.41.5-1.81.8-1.1-1.80.8
Latency to leave start box in cocaine runway, F0.80.82.41.3-1.0-0.20.2-0.11.3-0.31.50.0-1.5-0.1
Latency to leave start box in cocaine runway, M4.34.16.32.1-2.3-2.32.3-2.41.3-2.51.3-2.1-1.31.9
Std. dev. time between licks in bursts0.50.61.20.5-0.6-1.00.9-1.10.5-0.90.3-1.0-0.31.1
Total sessions with >9 infusions1.11.32.61.2-1.2-1.01.4-1.20.5-1.60.2-1.4-0.21.3
Short access day 1 total inactive lever presses0.40.41.20.90.21.1-0.70.60.80.40.60.5-0.6-0.5
Short access day 10 total inactive lever presses0.60.72.40.1-0.01.5-0.81.1-0.30.70.21.1-0.2-1.2
Short access day 1 total infusions0.10.10.20.3-0.10.10.1-0.10.4-0.30.2-0.3-0.10.3
Short access day 10 total infusions0.91.03.6-0.91.00.20.1-0.4-1.3-0.4-1.9-0.41.90.4
Short access total infusions0.30.30.80.3-0.3-0.30.7-0.6-0.4-0.9-0.7-0.60.80.5
Short access day 1 locomotion0.20.30.60.8-0.3-0.50.6-0.50.4-0.7-0.0-0.6-0.10.6
Short access day 10 total locomotion0.20.20.3-0.30.50.6-0.40.4-0.50.4-0.50.40.5-0.5
Short access total locomotion0.50.61.91.4-0.8-0.60.8-0.60.7-0.80.4-0.7-0.50.6
One hour access (0.3 mA shock)2.73.18.4-2.21.71.1-0.80.6-2.60.6-2.90.82.7-0.8
Compulsive drug intake0.90.93.5-1.01.90.9-1.40.80.41.40.00.50.2-0.1
One hour access (shock baseline)1.41.65.6-1.20.60.7-0.20.3-2.20.1-2.40.52.1-0.6
Social response proportion0.40.51.6-0.8-0.00.4-0.00.7-1.3-0.3-0.60.60.8-0.7
Social responses1.31.62.9-1.10.91.1-1.01.4-1.70.7-1.51.21.6-1.3
Social time4.56.07.4-2.52.12.7-2.32.7-2.72.2-2.12.72.2-2.7
Soleus weight1.54.36.42.3-1.6-2.01.6-2.42.5-1.62.5-1.9-2.32.0
Bone: stiffness0.50.93.21.8-1.5-0.30.6-0.10.8-0.71.0-0.1-1.2-0.1
Tibialis anterior weight3.110.516.03.0-2.5-2.82.7-3.14.0-2.73.8-3.4-3.73.5
Time to tail flick, vehicle, before self-admin0.20.20.4-0.0-0.5-0.60.4-0.4-0.6-0.3-0.40.00.4-0.3
Time to tail flick, vehicle, after self-admin0.20.20.9-1.00.3-0.1-0.0-0.0-0.60.0-0.50.10.5-0.1
Time to tail flick, test, before self-admin1.51.43.80.1-0.2-1.50.8-1.31.4-0.81.0-1.6-1.02.0
Time to tail flick, test, after self-admin2.02.04.82.2-1.5-1.81.6-1.70.8-1.50.4-1.5-0.41.2
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.50.50.4-0.20.20.30.20.2-0.1-0.20.3
Delta time to tail flick, test, before/after SA0.60.61.31.0-0.7-0.20.4-0.1-1.1-0.3-1.10.41.1-0.9
Tibia length0.10.41.50.3-0.10.6-0.60.5-0.60.5-0.21.10.4-1.2
Ambulatory time before self-admin0.10.10.2-0.00.0-0.3-0.20.0-0.40.2-0.40.30.4-0.4
Ambulatory time after self-admin0.40.41.10.30.10.8-0.80.80.10.80.21.0-0.2-1.1
Bone: tissue strength0.40.40.70.8-0.6-0.70.5-0.30.6-0.60.6-0.5-0.60.5
Total heroin consumption0.91.04.0-0.7-0.1-0.00.30.3-2.0-0.3-1.80.41.7-0.6
Bone: trabecular number3.14.97.5-1.32.02.5-2.52.6-1.62.5-1.62.71.6-2.7
Bone: trabecular spacing2.43.14.31.3-2.0-1.82.0-1.81.3-2.11.6-1.8-1.61.8
Bone: trabecular thickness5.26.27.7-2.12.62.8-2.72.8-2.02.7-2.22.62.1-2.5
Bone: trabecular tissue density0.20.20.5-0.10.30.5-0.50.50.60.50.70.3-0.7-0.1
Water consumed over 24 hours0.10.20.3-0.1-0.6-0.40.6-0.3-0.4-0.6-0.2-0.30.30.2
Number of responses in last shaping day0.30.30.70.40.30.8-0.80.8-0.30.4-0.10.70.2-0.7