Hub : Genes

Ncaph2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Ncaph2 0.07 0.05 1.4e-03 0.06 0.06 0.03 0.06 1.7e-03 1.1e-03 2.4e-02 2.1e-03
2 IL gene expression Ncaph2 0.21 0.13 2.0e-03 0.12 0.09 0.08 0.11 8.8e-04 3.5e-03 6.6e-03 1.5e-03
3 PL gene expression Ncaph2 0.05 0.04 1.6e-04 0.04 0.03 0.03 0.03 9.9e-05 1.6e-04 2.0e-04 1.5e-04
4 Brain gene expression Ncaph2 0.05 0.03 1.2e-05 0.06 0.06 0.05 0.05 5.3e-06 7.7e-06 3.4e-05 1.1e-05
5 pVTA gene expression Ncaph2 0.03 0.02 6.6e-03 0.03 0.02 0.01 0.03 1.8e-03 6.1e-03 2.8e-02 4.0e-03
6 NAcc gene expression Ncaph2 0.05 0.03 1.8e-07 0.05 0.04 0.04 0.04 9.5e-08 2.9e-07 6.9e-07 4.1e-07
7 Liver gene expression Ncaph2 0.15 0.06 0.0e+00 0.12 0.12 0.12 0.12 1.6e-13 4.9e-13 8.4e-13 4.6e-13
8 Liver mRNA stability Ncaph2 0.15 0.06 0.0e+00 0.18 0.19 0.2 0.19 1.8e-19 1.4e-20 2.4e-21 3.8e-21

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.91.72.81.7-1.5-1.5-1.4-1.0-1.01.0-1.0
Area under the delay curve0.60.91.40.8-0.9-0.9-0.7-0.9-1.11.1-1.2
BMI with tail4.214.815.9-3.94.04.03.73.93.8-3.83.7
BMI without tail1.47.48.2-2.72.82.82.42.92.7-2.72.8
Body weight1.98.39.9-3.12.82.83.12.92.8-2.82.7
Weight adjusted by age1.23.54.2-2.01.91.91.91.91.7-1.81.7
Bone surface0.91.82.51.6-1.6-1.6-1.3-1.2-1.11.0-1.2
Bone volume1.22.43.31.8-1.7-1.7-1.7-1.5-1.31.3-1.4
Breakpoint value in progressive ratio session0.10.10.2-0.40.30.30.50.30.3-0.30.2
Number of licking bursts0.00.00.00.2-0.1-0.1-0.10.00.00.00.0
Context. condit. distance diff. score2.12.52.8-1.61.61.61.61.51.6-1.61.7
Locomotion velocity, session 10.20.20.6-0.20.40.40.60.80.5-0.50.5
Locomotion distance, session 12.53.23.51.7-1.9-1.9-1.6-1.8-1.81.7-1.8
Locomotion velocity, session 20.81.01.3-0.70.90.90.91.01.1-1.11.0
Locomotion distance, session 21.11.51.91.1-1.4-1.4-1.1-1.3-1.21.1-1.2
Locomotion velocity, session 30.30.40.8-0.60.40.40.50.50.7-0.70.9
Locomotion distance, session 30.10.10.30.5-0.1-0.1-0.5-0.3-0.20.1-0.1
Stereotopy head waving bouts, day 32.22.73.51.9-1.6-1.6-1.7-1.6-1.61.5-1.6
Stereotopy head waving duration, day 30.81.01.31.1-1.0-1.0-1.1-0.9-0.90.9-0.9
Locomotion velocity, session 70.80.91.8-0.51.41.40.40.80.8-0.81.0
Locomotion distance, session 70.30.40.7-0.60.80.80.50.60.4-0.40.5
Stereotopy head waving bouts, day 70.91.11.91.0-1.4-1.4-1.0-1.0-0.70.7-0.7
Stereotopy head waving duration, day 70.91.11.61.2-1.3-1.3-1.2-1.1-0.70.7-0.7
Locomotion velocity, session 81.51.82.5-0.81.31.31.01.51.5-1.51.6
Locomotion distance, session 80.60.91.1-1.10.70.71.00.81.0-1.00.9
Degree of sensitization distance1.41.52.0-1.41.21.21.41.31.1-1.11.0
Degree of sensitization stereotypy0.10.10.30.1-0.6-0.6-0.2-0.20.1-0.00.1
Conditioned locomotion0.50.60.8-0.60.90.90.70.60.9-0.90.8
Cocaine response after cond. corrected1.11.72.1-1.21.21.21.21.31.4-1.41.4
Cocaine response after cond. not corrected2.73.94.6-1.91.81.81.92.02.1-2.12.1
Cocaine response before conditioning1.11.31.4-1.11.11.11.11.11.2-1.11.2
Saline control response0.50.71.0-0.90.70.71.01.00.9-0.90.8
Bone: connectivity density0.71.12.11.5-1.2-1.2-1.2-0.9-0.60.6-0.7
Bone: cortical apparent density2.13.43.61.9-1.8-1.8-1.8-1.8-1.91.9-1.8
Bone: cortical area0.20.30.6-0.40.80.80.50.40.4-0.40.3
Bone: cortical porosity0.20.20.4-0.40.40.40.60.50.6-0.40.3
Bone: cortical porosity0.70.81.5-1.00.60.61.20.91.0-0.80.7
Bone: cortical thickness0.00.10.10.10.20.2-0.1-0.2-0.30.3-0.3
Bone: cortical thickness0.30.41.5-0.41.21.20.20.20.1-0.10.3
Bone: cortical tissue density1.82.93.11.7-1.7-1.7-1.7-1.7-1.81.8-1.6
Condit. Reinf. active minus inactive responses1.21.31.9-0.51.41.40.91.21.3-1.31.2
Condit. Reinf. active-inactive response ratio0.20.20.30.20.40.40.20.40.5-0.50.5
Condit. Reinf. active responses2.02.63.2-1.11.81.81.41.71.7-1.71.6
Condit. Reinf. inactive responses1.41.92.1-1.31.41.41.31.41.4-1.41.3
Incentive salience index mean1.82.33.1-0.91.81.81.31.51.6-1.61.5
Condit. Reinf. lever presses1.42.12.7-1.11.61.61.31.41.5-1.51.4
Condit. Reinf. active minus inactive responses0.40.61.10.7-0.2-0.2-0.7-0.7-0.91.0-1.0
Condit. Reinf. active-inactive response ratio0.10.20.40.60.10.1-0.5-0.4-0.60.6-0.6
Condit. Reinf. active responses0.10.10.2-0.00.50.5-0.1-0.0-0.20.3-0.4
Condit. Reinf. inactive responses0.20.40.6-0.80.70.70.60.50.5-0.50.4
Condit. Reinf. lever presses0.60.81.5-0.91.21.20.80.70.8-0.80.6
Condit. Reinf. lever reinforcers received0.10.10.30.20.30.3-0.2-0.2-0.40.4-0.5
Conditioned reinforcement - actives0.10.60.7-0.80.80.80.80.80.7-0.70.6
Conditioned reinforcement - inactives0.10.30.5-0.50.60.60.60.70.5-0.50.5
Conditioned locomotion2.23.23.7-1.91.91.91.71.71.8-1.81.8
Patch foraging indifference point 0 sec0.20.50.6-0.80.70.70.80.60.7-0.70.6
Patch foraging indifference point AUC0.40.91.20.9-1.0-1.0-0.8-0.9-0.80.8-1.1
Delay disc. indifference point, 0s delay0.20.20.3-0.50.60.60.20.50.6-0.60.3
Delay disc. indifference point, 16s delay0.10.10.20.4-0.4-0.40.0-0.2-0.30.3-0.4
Delay disc. indifference point, 2s delay3.23.64.91.8-1.8-1.8-1.8-1.8-1.91.9-2.2
Delay disc. indifference point, 24s delay0.40.71.6-0.50.90.91.30.80.6-0.60.6
Delay disc. indifference point, 4s delay1.01.11.60.6-1.3-1.3-0.7-0.8-1.11.1-1.2
Delay disc. indifference point, 8s delay0.71.21.60.8-1.1-1.1-0.9-1.0-1.31.3-1.2
Indifference point function ln k1.13.34.4-2.12.12.11.51.51.7-1.71.8
Indifference point function log k1.13.34.4-2.12.12.11.51.51.7-1.71.8
Patch foraging total patch changes 0 sec0.10.20.4-0.50.50.50.60.40.4-0.40.4
Patch foraging total patch changes 12 sec0.00.00.10.3-0.1-0.1-0.1-0.2-0.10.0-0.3
Patch foraging total patch changes 18 sec1.02.32.71.6-1.4-1.4-1.4-1.5-1.61.5-1.6
Patch foraging total patch changes 24 sec0.20.61.21.1-0.5-0.5-1.0-0.8-0.70.7-0.7
Patch foraging total patch changes 6 sec0.00.10.20.0-0.5-0.50.3-0.0-0.10.1-0.3
Patch foraging time to switch 0 sec0.10.30.70.8-0.5-0.5-0.5-0.4-0.50.5-0.4
Patch foraging water rate 0 sec0.31.12.3-1.51.11.11.00.71.0-0.90.9
Patch foraging water rate 12 sec0.83.14.5-2.12.02.01.61.61.6-1.61.5
Patch foraging water rate 18 sec2.45.47.3-2.72.42.42.32.02.2-2.22.3
Patch foraging water rate 24 sec1.21.73.1-1.81.01.01.31.11.4-1.41.4
Patch foraging water rate 6 sec0.60.92.0-1.40.90.90.80.71.0-0.90.9
Seeking ratio, delayed vs. immediate footshock0.50.70.90.9-0.9-0.9-0.9-0.8-0.70.8-0.7
Distance traveled before self-admin0.81.82.31.3-1.3-1.3-1.5-1.4-1.31.3-1.2
Distance traveled after self-admin0.00.00.00.2-0.1-0.1-0.00.0-0.00.00.1
Extensor digitorum longus weight0.41.71.9-1.31.41.41.41.31.3-1.31.3
Bone: elastic displacement0.20.30.90.4-1.0-1.0-0.3-0.2-0.30.3-0.4
Bone: elastic work0.20.30.5-0.70.30.30.70.60.5-0.50.5
Bone: endosteal estimation0.10.30.4-0.60.50.50.60.50.6-0.60.4
Bone: endosteal perimeter0.10.30.5-0.30.60.60.50.60.7-0.70.3
Epididymis fat weight1.15.57.1-1.72.72.72.22.52.3-2.42.1
Delta time in closed arm before/after self-admin0.00.00.1-0.1-0.1-0.10.3-0.0-0.20.2-0.2
Delta time in open arm before/after self-admin0.00.00.10.0-0.0-0.0-0.2-0.20.1-0.1-0.1
Diff in mean of infusions in LGA sessions0.61.01.2-0.91.01.01.11.01.1-1.10.9
Delay discount exponential model param0.60.81.2-0.70.90.90.60.81.0-1.01.1
Extinction: sum of active levers before priming0.10.20.30.3-0.6-0.6-0.1-0.2-0.50.5-0.4
Active lever presses in extinction session 62.62.63.2-1.71.51.51.61.81.6-1.61.7
Bone: final force0.10.20.30.40.00.0-0.4-0.5-0.50.5-0.5
Bone: final moment0.20.20.40.5-0.3-0.3-0.5-0.6-0.60.6-0.6
Food consumed during 24 hour testing period1.63.23.3-1.81.81.81.81.71.8-1.81.8
Glucose0.10.20.40.3-0.6-0.6-0.4-0.4-0.40.4-0.5
Heart weight0.30.50.7-0.60.80.80.50.60.7-0.70.8
Delay discount hyperbolic model param1.01.31.8-0.91.11.10.91.11.2-1.21.3
Intermittent access intake day 1-15 change0.21.11.5-1.20.90.91.21.11.0-1.01.0
Intermittent access intake escalation0.21.21.6-1.31.01.01.21.11.0-1.01.0
Intermittent access intake escalation 21.11.92.4-1.41.31.31.51.51.3-1.31.2
Intermitt. access day 1 inactive lever presses0.10.70.9-1.00.80.80.90.80.8-0.80.7
Intermitt. access day 15 inactive lever presses0.84.24.9-2.22.02.01.91.92.1-2.12.2
Intermitt. access escalation Index0.10.30.40.6-0.5-0.5-0.6-0.6-0.50.5-0.4
Intermittent access day 1 total infusions0.00.00.0-0.10.20.20.10.10.2-0.20.2
Intermittent access day 15 total infusions0.10.30.5-0.70.50.50.60.60.5-0.50.5
Intermittent access terminal intake (last 3 days)0.91.62.0-1.41.21.21.41.31.2-1.21.1
Intermittent access total infusions0.20.20.3-0.50.50.50.50.40.4-0.40.4
Intermittent access day 1 locomotion0.00.00.10.0-0.0-0.0-0.3-0.2-0.00.0-0.1
Intermittent access day 15 total locomotion0.31.01.4-1.21.01.00.90.91.0-1.00.9
Intermittent access total locomotion0.70.81.2-1.10.90.90.70.71.0-1.00.9
Intermittent access standard deviation0.10.70.8-0.90.70.70.80.90.8-0.80.9
Left kidney weight3.124.628.2-5.14.64.65.35.25.0-5.14.8
Right kidney weight5.437.943.6-6.35.75.76.66.66.1-6.26.0
Cocaine induced anxiety0.61.51.9-1.41.21.21.41.21.2-1.21.2
Post-drug Anxiety1.71.92.5-1.51.31.31.61.41.3-1.31.4
Baseline Anxiety0.20.40.50.7-0.7-0.7-0.6-0.6-0.60.6-0.6
Tail length0.21.32.01.2-1.4-1.4-1.0-0.8-1.01.0-0.9
Length with tail0.00.10.3-0.1-0.3-0.30.5-0.0-0.10.1-0.2
Length without tail0.10.72.3-1.00.50.51.50.70.7-0.70.5
Times rat made contact with spout1.21.42.6-1.61.11.11.30.91.0-1.01.3
Lifetime Intake0.30.30.4-0.60.60.60.60.50.5-0.50.5
Liver weight, left0.10.10.4-0.60.30.30.30.50.2-0.20.1
Liver weight, right0.10.20.30.1-0.6-0.6-0.3-0.4-0.50.5-0.5
Locomotor activity0.10.20.3-0.40.30.30.10.50.6-0.50.3
Locomotor testing distance0.51.22.21.0-1.1-1.1-1.5-1.0-1.01.0-1.0
Locomotor testing rearing0.20.81.30.7-0.9-0.9-0.7-0.8-0.80.9-1.1
Locomotion in novel chamber1.41.92.4-1.51.31.31.51.41.5-1.11.4
Locomotion in novel chamber post-restriction0.10.31.10.6-0.3-0.3-1.1-0.5-0.30.3-0.4
Fecal boli incidents, locomotor time 10.20.60.90.7-0.7-0.7-0.9-0.8-0.80.8-0.7
Change in fecal boli incidents, locomotor task0.50.61.1-0.80.70.71.10.80.6-0.60.6
Time >=10cm from walls, locomotor time 10.30.40.6-0.60.50.50.70.80.7-0.70.6
Bouts of movement, locomotor time 10.40.60.9-0.30.80.80.90.90.6-0.60.8
Total resting periods, locomotor time 10.20.20.50.10.40.40.70.60.2-0.20.4
Rest time, locomotor task time 10.00.00.00.10.10.1-0.00.0-0.10.10.1
Distance moved, locomotor task time 10.00.10.2-0.30.30.30.20.10.5-0.50.3
Vertical activity count, locomotor time 10.10.71.0-0.81.01.00.50.60.9-0.90.6
Time >=10cm from walls, locomotor time 20.82.32.7-1.51.61.61.61.31.6-1.61.4
Bouts of movement, locomotor time 20.10.30.50.5-0.5-0.5-0.4-0.5-0.70.7-0.6
Total resting periods, locomotor time 20.10.40.60.7-0.6-0.6-0.6-0.6-0.80.8-0.7
Rest time, locomotor task time 20.40.60.90.8-0.9-0.9-0.7-0.7-0.80.8-0.6
Distance moved, locomotor task time 21.21.52.1-1.21.51.50.80.91.4-1.41.1
Vertical activity count, locomotor time 20.71.72.7-1.31.71.70.70.91.4-1.41.0
Light reinforcement 10.10.71.0-0.70.60.60.70.91.0-1.00.8
Light reinforcement 21.33.03.9-1.91.61.61.92.01.7-1.71.5
Bone: marrow area0.10.20.2-0.40.30.30.50.40.5-0.40.3
Bone: maximum diameter0.81.72.5-1.01.61.61.11.31.3-1.31.1
Bone: maximum force0.00.00.00.00.10.10.1-0.1-0.10.1-0.2
Bone: maximum moment0.00.00.10.1-0.2-0.2-0.0-0.2-0.30.3-0.3
Mean time between licks in bursts0.53.13.82.0-1.7-1.7-1.9-1.7-1.71.7-1.6
Mean num. licks in bursts0.10.20.8-0.90.40.40.60.20.2-0.30.4
Cd content in liver0.50.50.60.8-0.7-0.7-0.7-0.6-0.80.8-0.7
Co content in liver0.30.40.7-0.40.20.20.70.90.8-0.80.6
Cu content in liver0.30.30.70.6-0.1-0.1-0.8-0.7-0.70.7-0.4
Fe content in liver0.20.20.40.4-0.4-0.4-0.4-0.5-0.50.5-0.6
K content in liver0.10.10.40.6-0.3-0.3-0.5-0.1-0.00.0-0.1
Mg content in liver0.80.91.51.1-1.2-1.2-0.9-0.6-0.60.6-0.8
Mn content in liver0.10.10.20.3-0.1-0.1-0.20.10.4-0.40.2
Na content in liver5.36.07.82.6-2.0-2.0-2.8-2.7-2.42.4-2.5
Rb content in liver0.00.00.00.2-0.2-0.2-0.10.1-0.00.0-0.2
Se content in liver0.50.61.0-0.60.50.50.71.00.9-0.80.9
Sr content in liver1.41.21.81.1-1.0-1.0-1.2-1.3-1.11.1-1.0
Zn content in liver0.30.40.80.5-0.9-0.9-0.4-0.4-0.60.6-0.5
Bone: minimum diameter0.10.30.6-0.20.80.80.40.50.5-0.50.3
Time in familiar zone, hab. session 10.40.50.7-0.80.40.40.70.70.7-0.70.8
Time in novel zone, hab. session 10.80.91.41.2-0.9-0.9-1.0-0.9-0.80.8-0.9
Total zone transitions, hab. session 12.84.04.61.6-2.1-2.1-1.6-2.0-2.22.1-2.2
Total locomotion distance, hab. session 10.20.30.8-0.1-0.9-0.90.1-0.5-0.50.5-0.7
Locomotion velocity, hab. session 10.40.50.90.1-1.0-1.0-0.1-0.6-0.70.7-0.9
Time in familiar zone, hab. session 21.82.02.4-1.31.51.51.11.41.5-1.51.5
Time in novel zone, hab. session 22.02.12.91.5-1.7-1.7-1.3-1.3-1.41.4-1.4
Total zone transitions, hab. session 20.10.10.3-0.60.20.20.40.00.2-0.20.2
Total locomotion distance, hab. session 20.91.22.2-1.50.80.81.51.01.1-1.11.0
Locomotion velocity, hab. session 20.81.12.1-1.40.70.71.40.91.0-1.00.8
Novel to familiar place preference ratio0.10.10.40.6-0.3-0.3-0.6-0.3-0.10.10.0
Novelty place preference0.00.10.20.4-0.2-0.2-0.3-0.00.2-0.20.3
Time in novel zone, NPP test0.10.10.20.4-0.2-0.2-0.3-0.00.1-0.10.3
Total zone transitions, NPP test0.71.01.30.6-1.1-1.1-0.7-1.0-1.11.1-1.0
Total locomotion distance, NPP test0.00.10.1-0.2-0.4-0.40.30.0-0.10.0-0.2
Locomotion velocity, NPP test0.00.10.2-0.4-0.2-0.20.40.10.0-0.1-0.1
Intraocular pressure0.10.21.00.50.20.2-1.0-0.3-0.20.2-0.4
Delta distance traveled before/after self-admin4.14.54.7-1.92.22.22.22.12.1-2.12.1
Delta ambulatory time before/after self-admin1.62.83.1-1.41.71.71.71.61.7-1.71.7
Parametrial fat weight0.20.40.8-0.80.90.90.50.60.4-0.40.4
Pavlov. Cond. lever latency1.21.52.11.0-1.5-1.5-1.1-1.1-1.31.3-1.1
Pavlov. Cond. magazine entry latency0.20.30.70.8-0.1-0.1-0.7-0.5-0.40.4-0.4
Pavlov. Cond. change in total contacts0.10.10.50.70.30.3-0.5-0.2-0.10.1-0.2
Pavlov. Cond. index score0.10.10.20.30.40.4-0.20.00.1-0.10.0
Pavlov. Cond. latency score0.10.20.50.10.70.70.00.20.3-0.30.2
Pavlov. Cond. lever contacts1.11.32.0-0.71.41.40.91.11.2-1.21.0
Pavlov. Cond. magazine entry number0.30.40.9-1.00.20.20.80.50.6-0.60.6
Pavlov. Cond. intertrial magazine entries1.11.31.4-1.11.21.21.11.11.1-1.21.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.50.30.3-0.4-0.2-0.10.1-0.2
Pavlov. Cond. response bias0.20.20.4-0.00.70.70.30.50.4-0.40.4
Pavlov. Cond. lever latency1.52.12.61.3-1.6-1.6-1.4-1.5-1.31.3-1.4
Pavlov. Cond. magazine entry latency0.50.81.3-0.81.21.20.90.90.7-0.70.7
Pavlov. Cond. change in total contacts0.00.10.2-0.00.40.40.1-0.0-0.20.2-0.2
Pavlov. Cond. index score0.71.11.6-1.11.31.31.11.10.9-0.90.9
Pavlov. Cond. latency score1.21.92.6-1.41.61.61.41.41.2-1.21.2
Pavlov. Cond. lever contacts1.52.22.6-1.41.61.61.51.51.4-1.41.4
Pavlov. Cond. magazine entry number0.91.21.81.0-1.3-1.3-1.1-1.1-0.90.9-0.9
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.5-0.4-0.40.30.20.2-0.20.3
Pavlov. Cond. lever-magazine prob. diff.0.81.31.8-1.11.31.31.21.10.9-0.90.9
Pavlov. Cond. response bias0.50.71.0-0.61.01.00.80.90.7-0.70.7
Time in closed arm before self-admin1.22.25.61.7-1.0-1.0-2.4-1.7-1.01.0-1.4
Time in closed arm after self-admin0.40.40.90.7-0.4-0.4-0.9-0.8-0.50.5-0.8
Time in open arm before self-admin0.10.10.3-0.1-0.1-0.10.60.5-0.10.10.2
Time in open arm after self-admin0.10.10.3-0.30.10.10.60.40.1-0.10.2
Bone: periosteal estimation0.20.40.6-0.60.80.80.60.50.6-0.60.4
Bone: periosteal perimeter0.40.81.2-0.71.11.10.80.91.0-0.90.6
Bone: post-yield work0.61.01.50.8-0.9-0.9-0.8-1.1-1.21.1-1.0
Progressive ratio test 1 active lever presses0.00.10.1-0.10.20.20.30.30.2-0.20.3
Progressive ratio test 1 breakpoint0.00.00.1-0.00.10.10.20.20.1-0.10.2
Progressive ratio test 1 inactive lever presses0.10.20.4-0.30.40.40.60.50.3-0.30.3
Progressive ratio test 2 active lever presses0.81.11.4-1.11.01.01.11.21.1-1.11.1
Progressive ratio test 2 breakpoint0.70.81.1-0.90.80.81.01.00.9-0.90.9
Progressive ratio test 2 inactive lever presses0.41.21.5-1.20.90.91.21.21.1-1.11.0
Incentive Sensitization - Responses0.41.21.3-1.11.11.11.01.11.2-1.21.0
Incentive Sensitization - Breakpoint0.51.11.2-1.11.01.01.01.11.1-1.11.0
Sum of active levers in priming session hrs 5-60.10.10.10.00.20.20.10.40.3-0.30.3
Progressive ratio0.20.61.3-0.50.60.61.10.90.7-0.80.8
Food seeking constrained by brief footshock3.24.04.9-2.21.91.92.22.11.9-2.11.8
Seeking ratio, punishment vs. effort0.00.00.2-0.20.10.1-0.5-0.2-0.00.0-0.3
Retroperitoneal fat weight2.19.511.0-3.03.33.32.93.23.1-3.12.8
Reaction time number correct0.20.81.10.7-1.0-1.0-0.9-1.0-0.90.9-0.9
Reaction time mean minus median0.00.10.2-0.10.20.20.30.40.4-0.40.3
Reaction time mean minus median AUC0.00.30.5-0.40.30.30.60.70.6-0.60.6
Reaction time num false alarms0.10.10.40.7-0.3-0.3-0.5-0.2-0.20.2-0.2
Reaction time num false alarms AUC0.00.00.10.3-0.1-0.1-0.20.10.1-0.00.1
Reaction time trials correct on left0.20.81.10.7-1.0-1.0-0.9-1.0-0.90.9-0.9
Reaction time trials on left0.30.91.10.8-1.0-1.0-1.0-1.0-0.90.9-0.9
Reaction time mean0.00.10.20.30.00.0-0.4-0.2-0.20.2-0.0
Reaction time mean AUC0.00.10.30.5-0.1-0.1-0.5-0.3-0.30.3-0.1
Median of all reaction times0.00.10.30.40.00.0-0.5-0.2-0.20.30.0
Reaction time omissions0.20.30.70.8-0.5-0.5-0.5-0.4-0.50.4-0.3
Reaction time false alarm rate0.10.10.20.10.30.30.10.40.3-0.30.3
Reaction time premature initiation rate1.72.73.3-1.51.81.81.41.61.8-1.81.4
Reaction time premature initiations0.20.71.0-0.91.01.00.60.71.0-1.00.7
Std. dev. reaction times0.10.20.3-0.30.50.50.30.50.4-0.40.4
Reaction time trials completed0.30.91.10.8-1.0-1.0-1.0-1.0-0.90.9-0.9
Reaction time trials AUC0.20.50.70.6-0.8-0.8-0.8-0.8-0.70.7-0.7
Run reversals in cocaine runway, females0.10.20.3-0.20.20.20.60.60.3-0.30.5
Run reversals in cocaine runway, males0.80.91.00.9-1.0-1.0-0.7-0.8-1.01.0-1.0
Latency to leave start box in cocaine runway1.82.53.1-1.81.71.71.41.31.6-1.51.6
Latency to leave start box in cocaine runway, F3.84.85.5-2.22.32.31.81.82.3-2.22.3
Latency to leave start box in cocaine runway, M0.10.10.2-0.0-0.2-0.2-0.1-0.2-0.20.3-0.4
Std. dev. time between licks in bursts0.50.91.6-1.20.60.61.31.00.9-0.90.7
Total sessions with >9 infusions0.30.40.5-0.70.70.70.70.60.6-0.60.6
Short access day 1 total inactive lever presses3.06.06.3-2.42.42.42.52.52.4-2.42.4
Short access day 10 total inactive lever presses1.28.08.9-3.02.92.92.72.72.9-2.92.6
Short access day 1 total infusions0.81.61.8-1.41.31.31.41.31.2-1.21.2
Short access day 10 total infusions0.81.31.5-1.21.21.21.21.11.1-1.11.1
Short access total infusions0.71.11.3-1.11.01.01.11.01.0-1.01.0
Short access day 1 locomotion0.91.41.7-1.31.21.21.01.01.2-1.21.3
Short access day 10 total locomotion0.31.21.4-1.21.21.20.91.01.2-1.21.2
Short access total locomotion0.50.70.8-0.90.90.90.70.70.9-0.90.8
One hour access (0.3 mA shock)0.80.91.4-1.20.90.91.11.00.9-0.90.8
Compulsive drug intake0.00.00.00.2-0.1-0.1-0.2-0.2-0.10.1-0.1
One hour access (shock baseline)0.20.60.9-0.90.70.70.90.80.7-0.70.6
Social response proportion0.30.40.90.8-0.3-0.3-0.9-0.7-0.60.6-0.8
Social responses0.20.30.70.6-0.2-0.2-0.8-0.7-0.30.4-0.6
Social time0.40.60.9-0.90.80.80.70.70.7-0.70.9
Soleus weight1.23.53.9-2.01.91.91.91.91.9-1.81.8
Bone: stiffness0.10.20.30.4-0.2-0.2-0.4-0.6-0.60.5-0.5
Tibialis anterior weight0.00.20.3-0.20.40.40.30.30.4-0.40.5
Time to tail flick, vehicle, before self-admin1.41.72.1-1.31.21.21.11.51.4-1.41.2
Time to tail flick, vehicle, after self-admin0.30.60.9-0.81.01.00.60.20.9-0.90.8
Time to tail flick, test, before self-admin0.30.40.8-0.40.90.9-0.10.00.7-0.70.6
Time to tail flick, test, after self-admin3.53.74.5-2.02.12.11.41.62.1-2.12.0
Delta time to tail flick, vehicle, before/after SA0.80.81.80.9-0.7-0.7-1.0-1.4-0.80.8-0.8
Delta time to tail flick, test, before/after SA0.30.40.6-0.80.40.40.80.80.6-0.60.6
Tibia length1.64.35.71.6-1.9-1.9-1.8-2.3-2.42.4-2.2
Ambulatory time before self-admin0.10.40.70.5-0.6-0.6-0.8-0.7-0.60.6-0.5
Ambulatory time after self-admin0.10.20.3-0.30.50.50.40.50.5-0.50.6
Bone: tissue strength0.90.92.00.4-1.4-1.4-0.5-0.9-0.80.9-0.8
Total heroin consumption0.00.00.1-0.20.30.30.00.10.3-0.30.2
Bone: trabecular number0.61.12.11.4-1.3-1.3-1.1-0.8-0.60.7-0.7
Bone: trabecular spacing1.92.74.0-2.01.71.71.91.61.4-1.41.4
Bone: trabecular thickness0.10.20.30.6-0.3-0.3-0.5-0.4-0.30.3-0.5
Bone: trabecular tissue density1.62.94.11.5-1.4-1.4-1.4-1.8-2.02.0-1.9
Water consumed over 24 hours0.20.40.9-0.90.40.40.80.50.5-0.50.5
Number of responses in last shaping day0.10.10.10.2-0.3-0.3-0.2-0.3-0.30.3-0.2