Hub : Genes

Nabp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Nabp2 0.04 0.03 3.9e-04 0.01 0.03 0.03 0.02 4.1e-02 4.5e-04 2.8e-04 2.0e-03
2 Eye alternative TSS NM_001244819.1 0.29 0.17 4.4e-03 0.06 0.07 0.02 0.05 3.7e-02 3.0e-02 1.5e-01 5.4e-02
3 IC gene expression Nabp2 0.07 0.06 8.1e-03 0.02 0.03 0.02 0.04 4.4e-02 1.9e-02 5.7e-02 8.6e-03
4 Liver gene expression Nabp2 0.07 0.05 2.5e-05 0.04 0.04 0.04 0.04 1.5e-05 8.1e-05 7.5e-05 2.7e-05
5 Brain gene expression Nabp2 0.05 0.04 1.9e-03 0.03 0.03 0.02 0.03 8.0e-04 1.1e-03 4.8e-03 6.3e-04
6 pVTA gene expression Nabp2 0.06 0.04 5.3e-04 0.02 0.04 0.04 0.04 1.2e-02 1.8e-04 2.7e-04 4.9e-04
7 Adipose gene expression Nabp2 0.06 0.04 3.8e-05 0.04 0.04 0.04 0.04 1.0e-05 8.8e-05 6.5e-05 2.8e-05
8 NAcc gene expression Nabp2 0.04 0.03 2.1e-05 0.03 0.03 0.03 0.03 1.2e-05 5.7e-05 1.9e-05 4.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density3.05.16.6-2.6-0.1-1.9-2.6-2.6-2.4-2.4-2.4
Area under the delay curve0.50.64.5-2.1-0.20.2-0.2-0.2-0.2-0.2-0.2
BMI with tail2.48.131.83.3-5.63.81.01.0-1.91.11.1
BMI without tail0.61.97.41.1-2.72.00.70.7-0.80.70.6
Body weight0.52.35.81.6-2.42.31.11.1-0.21.21.1
Weight adjusted by age0.20.21.31.10.2-0.10.30.30.40.30.3
Bone surface6.111.114.5-3.40.5-3.2-3.8-3.8-3.3-3.7-3.6
Bone volume6.010.814.6-3.10.2-3.0-3.8-3.8-3.5-3.7-3.5
Breakpoint value in progressive ratio session0.20.21.3-0.41.1-0.2-0.1-0.10.6-0.1-0.1
Number of licking bursts1.52.44.01.6-2.01.91.71.70.21.41.1
Context. condit. distance diff. score0.10.10.40.6-0.60.30.30.3-0.10.30.2
Locomotion velocity, session 11.51.62.3-1.0-0.3-1.0-1.5-1.5-1.5-1.4-1.4
Locomotion distance, session 12.22.84.2-1.30.5-1.7-2.1-2.1-1.5-1.8-1.8
Locomotion velocity, session 23.33.85.6-1.41.3-2.3-2.4-2.4-1.3-2.1-2.1
Locomotion distance, session 24.46.214.5-3.82.0-2.6-2.7-2.7-1.0-2.2-2.1
Locomotion velocity, session 31.21.36.1-1.22.5-1.4-0.0-0.01.1-0.2-0.2
Locomotion distance, session 30.00.00.1-0.10.3-0.00.10.10.40.20.2
Stereotopy head waving bouts, day 32.22.67.6-1.82.8-2.1-1.3-1.30.5-1.0-1.0
Stereotopy head waving duration, day 31.31.65.2-0.92.3-1.9-1.0-1.00.4-0.8-0.8
Locomotion velocity, session 70.20.30.6-0.10.2-0.8-0.5-0.5-0.4-0.5-0.6
Locomotion distance, session 70.60.81.40.8-0.30.71.21.20.71.00.9
Stereotopy head waving bouts, day 71.71.92.7-1.61.0-1.5-1.5-1.5-0.8-1.4-1.4
Stereotopy head waving duration, day 72.12.53.1-1.71.0-1.6-1.8-1.8-1.1-1.7-1.7
Locomotion velocity, session 83.54.29.4-3.11.2-2.1-2.1-2.1-1.2-2.0-2.0
Locomotion distance, session 80.71.03.8-2.00.8-0.9-0.9-0.9-0.3-0.7-0.7
Degree of sensitization distance0.20.20.70.4-0.90.40.30.3-0.40.10.0
Degree of sensitization stereotypy0.70.71.1-0.9-0.2-0.5-1.0-1.0-1.0-0.9-1.0
Conditioned locomotion2.02.43.11.7-1.01.81.71.71.01.71.5
Cocaine response after cond. corrected2.32.73.92.0-1.71.81.81.80.61.71.3
Cocaine response after cond. not corrected2.63.14.22.1-1.72.01.91.90.81.81.6
Cocaine response before conditioning0.30.30.6-0.60.8-0.5-0.6-0.60.0-0.6-0.2
Saline control response0.60.81.91.2-0.91.40.40.40.40.90.9
Bone: connectivity density1.82.83.9-1.8-0.1-1.5-2.0-2.0-1.7-1.8-1.7
Bone: cortical apparent density0.30.41.80.6-1.30.60.20.2-0.7-0.0-0.0
Bone: cortical area1.42.14.6-0.6-1.0-0.9-1.6-1.6-2.1-1.5-1.7
Bone: cortical porosity0.40.40.6-0.5-0.0-0.7-0.8-0.8-0.8-0.8-0.7
Bone: cortical porosity0.91.01.6-0.5-0.3-0.9-1.2-1.2-1.3-1.2-1.1
Bone: cortical thickness0.61.13.10.3-1.6-0.1-0.8-0.8-1.8-0.8-1.0
Bone: cortical thickness0.50.61.10.7-1.01.00.70.70.20.70.6
Bone: cortical tissue density0.20.31.30.4-1.10.50.10.1-0.6-0.0-0.0
Condit. Reinf. active minus inactive responses0.60.72.5-0.41.6-1.4-0.6-0.60.4-0.4-0.4
Condit. Reinf. active-inactive response ratio0.20.20.70.80.5-0.10.20.20.70.40.5
Condit. Reinf. active responses1.72.14.7-1.32.0-2.2-1.3-1.3-0.2-1.2-1.3
Condit. Reinf. inactive responses1.82.23.6-1.81.4-1.9-1.3-1.3-0.7-1.5-1.6
Incentive salience index mean1.21.43.0-0.91.3-1.7-1.3-1.3-0.4-1.1-1.1
Condit. Reinf. lever presses2.12.93.7-1.70.6-1.8-1.9-1.9-1.5-1.9-1.9
Condit. Reinf. active minus inactive responses0.91.13.30.21.8-0.30.80.81.80.80.8
Condit. Reinf. active-inactive response ratio1.92.24.31.10.90.81.71.72.11.61.7
Condit. Reinf. active responses0.40.62.7-0.61.7-1.00.00.00.9-0.0-0.0
Condit. Reinf. inactive responses0.50.61.1-0.90.7-1.0-0.7-0.7-0.4-0.8-0.8
Condit. Reinf. lever presses0.71.04.0-0.72.0-0.40.50.51.50.50.4
Condit. Reinf. lever reinforcers received0.40.52.0-0.31.4-0.60.40.41.10.30.3
Conditioned reinforcement - actives0.20.32.2-1.5-0.0-0.70.10.10.00.10.1
Conditioned reinforcement - inactives0.30.50.70.7-0.60.40.80.80.50.80.8
Conditioned locomotion1.62.06.1-2.51.7-2.1-0.8-0.80.1-0.8-0.9
Patch foraging indifference point 0 sec0.81.56.80.7-2.61.1-0.3-0.3-1.7-0.3-0.3
Patch foraging indifference point AUC0.20.31.1-0.21.0-0.50.30.30.70.20.3
Delay disc. indifference point, 0s delay2.42.75.1-2.3-1.3-0.6-1.5-1.5-2.2-1.5-1.5
Delay disc. indifference point, 16s delay0.10.10.2-0.40.4-0.3-0.3-0.3-0.0-0.3-0.3
Delay disc. indifference point, 2s delay0.80.92.6-1.6-0.50.2-0.8-0.8-1.1-0.8-0.8
Delay disc. indifference point, 24s delay0.40.53.3-1.8-0.60.50.00.0-0.20.00.0
Delay disc. indifference point, 4s delay1.31.34.0-2.00.5-1.0-1.1-1.1-0.8-1.1-1.1
Delay disc. indifference point, 8s delay0.60.72.6-1.6-0.40.70.80.80.50.80.8
Indifference point function ln k0.10.10.60.8-0.30.20.00.0-0.10.10.1
Indifference point function log k0.10.10.60.8-0.30.20.00.0-0.10.10.1
Patch foraging total patch changes 0 sec0.71.36.00.8-2.41.0-0.3-0.3-1.5-0.3-0.2
Patch foraging total patch changes 12 sec0.81.02.81.0-1.71.40.70.7-0.10.80.8
Patch foraging total patch changes 18 sec0.00.10.1-0.3-0.20.1-0.3-0.3-0.3-0.3-0.0
Patch foraging total patch changes 24 sec0.20.30.7-0.2-0.80.5-0.4-0.4-0.9-0.5-0.4
Patch foraging total patch changes 6 sec0.71.03.41.8-1.80.5-0.0-0.0-1.1-0.1-0.2
Patch foraging time to switch 0 sec0.30.71.2-0.6-0.6-0.5-0.9-0.9-1.1-0.8-0.8
Patch foraging water rate 0 sec0.61.22.10.7-0.91.41.31.30.71.21.0
Patch foraging water rate 12 sec0.61.32.51.2-1.11.61.11.10.61.21.1
Patch foraging water rate 18 sec3.24.96.32.5-0.12.32.42.42.32.32.3
Patch foraging water rate 24 sec5.27.310.13.0-1.43.23.03.02.02.82.7
Patch foraging water rate 6 sec1.42.13.61.50.71.11.51.51.91.51.6
Seeking ratio, delayed vs. immediate footshock0.91.01.8-1.31.3-0.9-1.0-1.0-0.3-1.0-1.0
Distance traveled before self-admin0.30.42.0-0.11.4-0.7-0.4-0.40.4-0.4-0.4
Distance traveled after self-admin0.10.11.1-1.10.10.20.00.00.10.00.0
Extensor digitorum longus weight2.07.923.52.8-4.94.11.71.7-0.52.22.1
Bone: elastic displacement0.10.10.2-0.3-0.1-0.1-0.4-0.4-0.2-0.2-0.1
Bone: elastic work0.50.61.4-0.5-1.10.2-0.7-0.7-1.2-0.7-0.7
Bone: endosteal estimation0.30.61.6-0.1-1.0-0.2-0.7-0.7-1.3-0.7-0.7
Bone: endosteal perimeter0.91.92.6-1.50.8-1.6-1.6-1.6-0.9-1.3-1.4
Epididymis fat weight0.41.22.01.00.40.81.21.21.41.31.2
Delta time in closed arm before/after self-admin4.74.46.52.5-1.22.62.22.21.52.22.2
Delta time in open arm before/after self-admin0.20.20.9-0.0-1.00.70.20.2-0.30.20.2
Diff in mean of infusions in LGA sessions0.50.62.7-0.61.6-0.9-0.0-0.00.9-0.00.0
Delay discount exponential model param0.50.54.12.00.0-0.20.20.20.10.20.2
Extinction: sum of active levers before priming0.80.92.3-0.21.4-0.10.80.81.50.80.8
Active lever presses in extinction session 60.20.20.6-0.40.4-0.7-0.5-0.5-0.2-0.5-0.4
Bone: final force1.32.16.2-0.4-2.1-0.2-1.0-1.0-2.5-1.3-1.5
Bone: final moment1.32.16.2-0.5-2.1-0.2-1.1-1.1-2.5-1.3-1.5
Food consumed during 24 hour testing period0.10.10.50.3-0.70.5-0.1-0.1-0.30.1-0.1
Glucose0.40.62.50.5-1.61.10.30.3-0.50.30.3
Heart weight0.30.41.00.30.60.20.60.61.00.80.8
Delay discount hyperbolic model param0.60.74.52.10.3-0.20.40.40.50.40.4
Intermittent access intake day 1-15 change0.30.51.30.80.80.30.70.71.10.70.7
Intermittent access intake escalation0.30.61.40.80.70.30.70.71.20.70.8
Intermittent access intake escalation 20.20.20.9-0.00.90.10.30.30.80.30.3
Intermitt. access day 1 inactive lever presses0.52.03.71.30.70.71.51.51.91.51.5
Intermitt. access day 15 inactive lever presses0.30.73.3-1.81.1-0.40.20.20.90.20.3
Intermitt. access escalation Index0.60.92.3-1.5-0.2-0.6-0.9-0.9-1.0-0.9-0.9
Intermittent access day 1 total infusions0.60.96.6-2.6-0.50.10.40.40.10.40.4
Intermittent access day 15 total infusions0.30.43.2-1.80.0-0.2-0.0-0.0-0.0-0.00.0
Intermittent access terminal intake (last 3 days)1.01.38.5-2.90.2-0.8-0.6-0.6-0.5-0.6-0.6
Intermittent access total infusions0.80.97.1-2.7-0.3-0.4-0.1-0.1-0.3-0.1-0.1
Intermittent access day 1 locomotion0.60.71.0-1.0-0.20.41.01.00.81.00.9
Intermittent access day 15 total locomotion0.20.30.7-0.40.5-0.20.50.50.80.50.6
Intermittent access total locomotion0.40.42.5-1.60.3-0.10.40.40.50.40.4
Intermittent access standard deviation0.40.81.9-1.41.0-1.4-0.6-0.6-0.1-0.6-0.6
Left kidney weight0.10.20.60.8-0.00.50.50.50.40.50.4
Right kidney weight0.10.61.10.90.80.10.90.91.10.80.5
Cocaine induced anxiety1.42.02.5-1.11.4-1.4-1.6-1.6-0.8-1.6-1.6
Post-drug Anxiety3.23.44.7-2.20.9-1.1-2.2-2.2-1.6-2.2-2.1
Baseline Anxiety0.00.10.2-0.5-0.10.3-0.1-0.1-0.1-0.1-0.1
Tail length0.83.215.5-1.43.9-1.90.20.22.10.1-0.1
Length with tail0.41.77.0-0.22.6-0.70.80.82.10.70.6
Length without tail0.30.92.51.6-0.91.10.90.90.30.90.8
Times rat made contact with spout0.81.01.81.3-1.21.20.80.80.30.91.1
Lifetime Intake1.01.27.7-2.8-0.8-0.2-0.3-0.3-0.7-0.3-0.2
Liver weight, left0.30.41.51.2-0.90.70.40.4-0.10.40.2
Liver weight, right0.20.30.60.30.40.40.70.70.80.60.5
Locomotor activity1.42.25.5-0.92.4-2.0-1.4-1.4-0.0-1.4-1.1
Locomotor testing distance0.71.22.7-0.41.7-1.5-1.1-1.1-0.2-1.1-1.0
Locomotor testing rearing0.20.31.61.20.10.40.30.30.50.40.5
Locomotion in novel chamber0.00.00.10.2-0.30.1-0.0-0.0-0.2-0.00.0
Locomotion in novel chamber post-restriction0.81.36.8-0.92.6-1.0-0.5-0.51.0-0.4-0.3
Fecal boli incidents, locomotor time 10.81.22.31.3-1.01.51.01.00.51.01.0
Change in fecal boli incidents, locomotor task1.71.72.6-0.80.8-1.6-1.5-1.5-1.0-1.5-1.5
Time >=10cm from walls, locomotor time 11.01.12.2-0.5-0.7-0.7-1.2-1.2-1.5-1.2-1.2
Bouts of movement, locomotor time 10.30.30.90.90.9-0.70.20.20.70.20.2
Total resting periods, locomotor time 10.40.41.80.31.4-0.9-0.0-0.00.7-0.0-0.0
Rest time, locomotor task time 10.50.61.3-1.10.8-0.9-0.7-0.7-0.2-0.7-0.7
Distance moved, locomotor task time 10.91.32.7-0.5-0.9-0.7-1.2-1.2-1.6-1.2-1.2
Vertical activity count, locomotor time 10.30.72.71.6-1.30.60.30.3-0.40.30.3
Time >=10cm from walls, locomotor time 20.50.81.61.0-1.11.30.80.80.10.80.7
Bouts of movement, locomotor time 20.61.02.4-0.30.4-1.5-1.1-1.1-0.8-1.1-1.1
Total resting periods, locomotor time 20.81.42.9-0.70.4-1.7-1.3-1.3-1.0-1.3-1.3
Rest time, locomotor task time 20.91.24.0-2.00.3-0.9-1.0-1.0-0.8-1.0-1.0
Distance moved, locomotor task time 20.50.61.01.0-0.20.50.90.90.80.90.9
Vertical activity count, locomotor time 21.62.35.52.3-1.21.51.41.40.81.41.5
Light reinforcement 11.12.77.5-2.12.7-2.2-1.2-1.20.4-1.2-1.0
Light reinforcement 20.30.51.7-0.51.3-0.9-0.6-0.60.3-0.5-0.3
Bone: marrow area0.20.51.4-0.1-0.9-0.2-0.6-0.6-1.2-0.6-0.7
Bone: maximum diameter1.42.63.6-1.40.9-1.9-1.8-1.8-1.2-1.7-1.7
Bone: maximum force1.01.85.3-0.3-2.20.1-0.9-0.9-2.3-1.0-1.2
Bone: maximum moment1.01.85.2-0.3-2.20.1-1.0-1.0-2.3-1.0-1.2
Mean time between licks in bursts0.10.31.10.31.1-0.60.20.20.70.30.0
Mean num. licks in bursts0.30.51.0-0.50.9-0.8-1.0-1.00.0-0.6-0.2
Cd content in liver0.10.10.30.20.6-0.6-0.4-0.40.1-0.1-0.2
Co content in liver0.70.83.50.11.9-0.70.20.21.30.40.4
Cu content in liver1.11.32.30.6-0.5-1.0-1.3-1.3-1.5-1.3-1.2
Fe content in liver0.30.31.01.0-0.50.20.60.60.20.50.5
K content in liver1.11.11.7-0.60.9-1.3-1.3-1.3-0.5-1.0-1.0
Mg content in liver0.70.71.4-0.61.2-1.2-0.9-0.9-0.1-0.8-0.7
Mn content in liver4.75.28.0-1.71.3-2.8-2.6-2.6-1.8-2.6-2.4
Na content in liver0.50.50.9-0.4-0.3-0.5-0.8-0.8-0.9-0.9-0.7
Rb content in liver1.11.32.20.6-0.4-0.9-1.2-1.2-1.5-1.4-1.5
Se content in liver0.00.10.30.50.1-0.3-0.2-0.20.00.0-0.1
Sr content in liver0.40.40.7-0.20.40.10.80.80.80.70.7
Zn content in liver2.32.66.01.31.80.21.51.52.51.61.6
Bone: minimum diameter0.81.42.4-0.8-0.5-0.8-1.5-1.5-1.5-1.2-1.3
Time in familiar zone, hab. session 11.21.25.2-0.92.3-0.80.30.31.50.30.3
Time in novel zone, hab. session 11.61.64.3-0.5-1.9-0.0-1.0-1.0-2.1-1.1-1.1
Total zone transitions, hab. session 12.02.85.6-2.40.8-1.6-1.8-1.8-1.2-1.7-1.7
Total locomotion distance, hab. session 14.86.814.5-3.81.6-2.9-2.6-2.6-1.6-2.5-2.5
Locomotion velocity, hab. session 13.54.99.9-3.11.7-2.6-2.3-2.3-1.1-2.0-2.1
Time in familiar zone, hab. session 21.51.65.7-0.32.4-0.50.80.82.00.80.8
Time in novel zone, hab. session 21.91.95.90.1-2.40.4-0.9-0.9-2.3-1.1-1.0
Total zone transitions, hab. session 22.53.35.6-0.8-0.7-1.2-2.4-2.4-2.2-1.8-1.9
Total locomotion distance, hab. session 21.62.13.8-2.00.7-1.5-1.7-1.7-1.0-1.3-1.4
Locomotion velocity, hab. session 22.43.25.2-2.30.7-1.8-2.1-2.1-1.3-1.7-1.8
Novel to familiar place preference ratio1.61.74.7-0.4-1.8-0.1-1.1-1.1-2.2-1.4-1.3
Novelty place preference1.31.43.7-0.5-1.4-0.2-1.1-1.1-1.9-1.3-1.3
Time in novel zone, NPP test1.31.43.8-0.2-1.6-0.0-1.0-1.0-1.9-1.2-1.2
Total zone transitions, NPP test0.81.11.8-1.0-0.7-0.4-1.3-1.3-1.4-1.0-1.0
Total locomotion distance, NPP test1.52.04.6-2.2-0.1-1.0-1.5-1.5-1.4-1.3-1.4
Locomotion velocity, NPP test1.42.05.3-2.30.2-1.2-1.5-1.5-1.2-1.3-1.3
Intraocular pressure1.31.82.90.50.51.41.51.51.71.41.6
Delta distance traveled before/after self-admin0.30.30.8-0.4-0.90.80.40.4-0.10.40.4
Delta ambulatory time before/after self-admin0.20.30.8-0.8-0.90.3-0.1-0.1-0.7-0.1-0.2
Parametrial fat weight0.10.21.00.1-1.00.3-0.1-0.1-0.8-0.2-0.3
Pavlov. Cond. lever latency1.41.82.51.1-0.31.31.51.51.41.61.6
Pavlov. Cond. magazine entry latency0.30.42.1-0.01.5-1.0-0.1-0.10.6-0.2-0.2
Pavlov. Cond. change in total contacts0.10.10.70.8-0.4-0.00.10.1-0.4-0.1-0.2
Pavlov. Cond. index score0.50.61.2-0.40.8-1.1-0.8-0.8-0.5-0.9-0.9
Pavlov. Cond. latency score0.91.21.9-0.80.8-1.4-1.1-1.1-0.8-1.2-1.3
Pavlov. Cond. lever contacts1.21.52.0-1.00.0-1.1-1.3-1.3-1.4-1.4-1.4
Pavlov. Cond. magazine entry number0.20.20.9-0.5-1.00.5-0.3-0.3-0.5-0.0-0.0
Pavlov. Cond. intertrial magazine entries0.70.81.20.50.20.71.11.11.11.11.0
Pavlov. Cond. lever-magazine prob. diff.0.40.61.3-0.40.8-1.1-0.7-0.7-0.3-0.8-0.8
Pavlov. Cond. response bias0.10.10.70.10.8-0.50.00.00.3-0.1-0.2
Pavlov. Cond. lever latency0.40.62.61.1-1.60.50.20.2-0.70.20.2
Pavlov. Cond. magazine entry latency0.60.73.3-0.81.8-1.0-0.1-0.10.6-0.4-0.3
Pavlov. Cond. change in total contacts0.20.21.2-0.11.1-0.30.20.20.70.10.2
Pavlov. Cond. index score0.40.63.1-0.61.8-0.60.00.00.8-0.1-0.1
Pavlov. Cond. latency score0.50.73.4-0.91.8-0.9-0.3-0.30.6-0.4-0.3
Pavlov. Cond. lever contacts0.30.52.4-0.71.5-0.20.20.20.90.10.1
Pavlov. Cond. magazine entry number0.60.73.50.7-1.91.10.10.1-0.50.50.5
Pavlov. Cond. intertrial magazine entries0.60.91.81.2-1.31.30.70.70.20.80.9
Pavlov. Cond. lever-magazine prob. diff.0.50.73.5-0.81.9-0.9-0.1-0.10.7-0.3-0.3
Pavlov. Cond. response bias0.50.73.7-0.51.9-0.40.40.41.20.20.2
Time in closed arm before self-admin0.70.91.4-0.7-0.2-0.6-1.1-1.1-1.2-1.1-1.1
Time in closed arm after self-admin0.30.31.20.7-0.71.10.30.3-0.10.30.3
Time in open arm before self-admin0.00.00.20.20.1-0.50.10.10.20.10.2
Time in open arm after self-admin0.50.62.00.5-1.40.70.70.7-0.10.70.7
Bone: periosteal estimation1.12.35.2-0.7-1.2-0.9-1.6-1.6-2.3-1.6-1.7
Bone: periosteal perimeter1.42.33.4-1.10.1-1.5-1.8-1.8-1.7-1.7-1.7
Bone: post-yield work0.10.20.70.1-0.90.50.30.3-0.50.1-0.1
Progressive ratio test 1 active lever presses0.40.53.0-1.7-0.70.20.40.4-0.10.40.3
Progressive ratio test 1 breakpoint0.40.53.0-1.7-0.70.30.40.4-0.00.40.4
Progressive ratio test 1 inactive lever presses0.30.42.4-1.60.5-0.6-0.0-0.00.2-0.0-0.0
Progressive ratio test 2 active lever presses0.60.74.9-2.20.2-0.7-0.1-0.10.0-0.1-0.1
Progressive ratio test 2 breakpoint0.70.85.3-2.30.3-0.7-0.1-0.10.1-0.1-0.1
Progressive ratio test 2 inactive lever presses0.91.59.7-3.1-0.3-0.8-0.6-0.6-0.7-0.6-0.6
Incentive Sensitization - Responses0.20.31.3-1.10.7-0.60.00.00.40.00.0
Incentive Sensitization - Breakpoint0.30.41.9-1.40.8-0.8-0.2-0.20.3-0.2-0.2
Sum of active levers in priming session hrs 5-60.10.10.5-0.70.40.30.10.10.40.10.2
Progressive ratio0.61.02.71.7-1.40.60.90.90.00.80.8
Food seeking constrained by brief footshock0.40.52.6-0.81.6-0.5-0.0-0.00.9-0.00.0
Seeking ratio, punishment vs. effort0.71.04.0-1.52.0-0.4-0.5-0.50.7-0.4-0.3
Retroperitoneal fat weight1.35.310.42.3-3.23.22.22.20.32.01.9
Reaction time number correct0.81.62.90.3-1.21.71.51.50.61.31.2
Reaction time mean minus median0.20.41.9-0.61.4-0.7-0.4-0.40.3-0.4-0.4
Reaction time mean minus median AUC1.23.06.9-2.61.4-1.8-1.6-1.6-0.9-1.7-1.8
Reaction time num false alarms0.30.41.00.9-1.00.60.50.5-0.10.40.5
Reaction time num false alarms AUC0.40.71.21.1-1.01.00.70.70.10.70.8
Reaction time trials correct on left0.81.62.90.3-1.21.71.51.50.61.31.2
Reaction time trials on left0.71.42.70.1-1.11.61.41.40.61.21.1
Reaction time mean1.11.73.3-1.81.3-1.3-1.3-1.3-0.5-1.2-1.2
Reaction time mean AUC0.91.42.8-1.70.9-1.0-1.3-1.3-0.7-1.1-1.1
Median of all reaction times1.01.53.2-1.81.0-1.2-1.3-1.3-0.7-1.2-1.2
Reaction time omissions0.40.61.3-1.10.1-0.5-0.8-0.8-0.9-0.8-1.0
Reaction time false alarm rate0.10.10.30.5-0.5-0.0-0.3-0.3-0.4-0.2-0.1
Reaction time premature initiation rate0.70.92.50.61.3-0.10.80.81.60.90.8
Reaction time premature initiations1.12.03.90.80.70.91.61.62.01.61.5
Std. dev. reaction times0.51.01.9-1.41.1-1.0-0.9-0.9-0.4-0.9-0.9
Reaction time trials completed0.71.42.70.1-1.11.61.41.40.61.21.1
Reaction time trials AUC1.01.93.40.4-1.21.81.61.60.81.41.4
Run reversals in cocaine runway, females2.12.14.7-2.21.8-2.2-0.9-0.9-0.2-1.1-1.3
Run reversals in cocaine runway, males1.61.63.1-1.81.7-1.3-1.2-1.2-0.3-1.2-1.2
Latency to leave start box in cocaine runway1.41.52.4-0.9-0.3-0.8-1.5-1.5-1.6-1.4-1.4
Latency to leave start box in cocaine runway, F2.63.04.3-1.8-0.3-1.1-2.0-2.0-2.1-1.9-1.9
Latency to leave start box in cocaine runway, M0.30.31.01.0-0.10.50.50.50.50.50.5
Std. dev. time between licks in bursts1.11.52.2-1.00.9-1.5-1.3-1.3-0.8-1.2-1.5
Total sessions with >9 infusions0.40.42.1-1.4-0.7-0.1-0.3-0.3-0.7-0.3-0.3
Short access day 1 total inactive lever presses0.30.51.21.10.70.10.50.50.90.50.5
Short access day 10 total inactive lever presses1.02.55.52.30.31.01.61.61.81.61.6
Short access day 1 total infusions0.20.30.7-0.9-0.7-0.1-0.3-0.3-0.7-0.3-0.2
Short access day 10 total infusions0.40.53.9-2.0-0.5-0.00.20.2-0.10.20.2
Short access total infusions0.81.16.3-2.5-1.0-0.3-0.4-0.4-0.9-0.4-0.3
Short access day 1 locomotion0.30.30.9-1.00.7-0.40.40.40.70.40.3
Short access day 10 total locomotion0.91.74.50.11.5-0.21.31.32.11.31.3
Short access total locomotion0.30.30.8-0.90.6-0.20.50.50.80.50.5
One hour access (0.3 mA shock)0.10.10.2-0.1-0.40.30.40.40.20.40.5
Compulsive drug intake0.20.31.61.20.2-0.1-0.4-0.4-0.2-0.4-0.3
One hour access (shock baseline)0.40.63.8-2.00.1-0.30.30.30.40.30.3
Social response proportion0.50.51.3-0.71.1-1.1-0.5-0.5-0.0-0.6-0.7
Social responses3.44.413.3-2.23.6-2.8-1.5-1.50.5-1.4-1.4
Social time0.81.13.41.9-1.31.20.60.60.00.70.9
Soleus weight1.75.120.42.5-4.53.00.60.6-1.70.80.7
Bone: stiffness0.91.56.60.1-2.60.4-0.2-0.2-2.1-0.6-0.9
Tibialis anterior weight0.41.35.41.1-2.31.70.00.0-0.90.40.3
Time to tail flick, vehicle, before self-admin0.90.91.3-0.71.1-0.5-1.2-1.2-0.5-1.2-1.1
Time to tail flick, vehicle, after self-admin1.01.42.51.10.60.61.31.31.61.31.3
Time to tail flick, test, before self-admin1.51.52.7-0.80.8-1.7-1.3-1.3-0.9-1.3-1.4
Time to tail flick, test, after self-admin0.40.41.3-1.1-0.0-0.3-0.6-0.6-0.6-0.6-0.6
Delta time to tail flick, vehicle, before/after SA2.52.43.01.6-1.11.41.71.71.11.71.7
Delta time to tail flick, test, before/after SA1.21.22.00.3-0.11.41.21.21.21.21.3
Tibia length0.30.92.9-1.41.7-0.70.50.51.20.30.2
Ambulatory time before self-admin0.10.10.60.10.8-0.3-0.1-0.10.3-0.1-0.1
Ambulatory time after self-admin0.20.21.5-1.2-0.00.2-0.1-0.1-0.1-0.1-0.1
Bone: tissue strength1.31.36.00.8-2.40.9-0.2-0.2-1.6-0.3-0.3
Total heroin consumption1.11.33.3-1.81.7-1.3-0.8-0.80.2-0.8-0.8
Bone: trabecular number1.83.05.8-2.40.8-1.6-1.9-1.9-1.3-1.8-1.7
Bone: trabecular spacing4.15.58.02.8-0.52.12.62.62.22.62.5
Bone: trabecular thickness7.18.911.4-2.9-0.1-2.7-3.3-3.3-3.4-3.4-3.3
Bone: trabecular tissue density2.33.47.82.5-2.82.31.61.6-0.31.21.2
Water consumed over 24 hours0.50.71.5-0.1-0.9-0.2-1.0-1.0-1.2-0.8-0.7
Number of responses in last shaping day0.70.82.4-0.81.6-0.60.50.51.30.50.5