Hub : Genes

Nabp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr9_57619315_57619422 0.05 0.04 3.9e-04 0.02 0.02 0.02 0.02 4.4e-03 3.4e-03 6.0e-03 2.9e-03
2 Adipose intron excision ratio chr9_57618761_57619422 0.04 0.03 7.4e-04 0 0.01 0.01 0 9.3e-02 1.8e-02 4.6e-02 1.1e-01
3 IC gene expression Nabp1 0.09 0.06 2.4e-04 0.07 0.08 0.04 0.07 5.8e-04 2.6e-04 7.2e-03 4.8e-04
4 Brain gene expression Nabp1 0.04 0.03 2.2e-04 0.02 0.03 0.03 0.03 6.1e-03 5.6e-04 1.5e-03 1.9e-03
5 Liver alternative TSS XM_063267373.1 0.03 0.03 3.6e-03 0.01 0.01 0 0.01 3.1e-02 8.3e-03 8.0e-02 1.7e-02
6 PL gene expression Nabp1 0.06 0.04 2.8e-06 0.03 0.04 0.03 0.03 6.0e-04 9.0e-05 4.7e-04 3.2e-04
7 Liver isoform ratio XM_063267373.1 0.05 0.05 2.3e-03 0.01 0.01 0 0.01 5.2e-02 1.5e-02 9.0e-02 2.1e-02
8 Liver alternative TSS XM_063267373.1 0.05 0.05 3.2e-03 0.01 0.01 0.01 0.01 5.4e-02 9.1e-03 7.9e-03 1.3e-02
9 Liver alternative polyA XM_063267373.1 0.18 0.13 7.7e-03 0.02 0.01 0.01 0.01 3.4e-03 4.5e-02 2.8e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.13.21.8-1.41.31.1-0.80.7-0.50.5-0.4
Area under the delay curve1.62.44.3-0.71.0-1.2-1.51.8-2.02.1-1.9-1.2
BMI with tail3.010.417.5-3.64.2-4.0-3.83.2-3.02.7-2.3-0.5
BMI without tail0.42.13.4-1.01.8-1.8-1.71.5-1.31.3-1.3-0.8
Body weight0.21.12.11.4-0.80.91.0-1.21.3-1.20.9-0.1
Weight adjusted by age0.20.62.11.5-0.90.60.5-0.10.10.2-0.4-1.2
Bone surface0.10.21.21.1-0.50.40.3-0.1-0.00.2-0.1-0.4
Bone volume0.51.03.61.9-1.41.21.1-0.70.6-0.30.2-0.6
Breakpoint value in progressive ratio session0.30.50.90.5-1.00.90.8-0.80.7-0.70.3-0.6
Number of licking bursts0.00.10.50.0-0.00.20.3-0.50.6-0.70.20.0
Context. condit. distance diff. score1.21.41.8-1.41.2-1.3-1.31.3-1.31.2-1.1-0.7
Locomotion velocity, session 11.01.12.0-0.80.8-1.0-1.01.3-1.31.4-0.9-0.3
Locomotion distance, session 10.91.12.2-0.60.8-1.0-1.01.4-1.41.5-0.9-0.3
Locomotion velocity, session 22.83.44.2-2.02.0-2.0-2.02.0-2.01.9-1.30.3
Locomotion distance, session 20.30.50.7-0.60.8-0.8-0.70.8-0.70.7-0.10.7
Locomotion velocity, session 31.41.65.4-0.2-0.40.70.8-1.11.1-1.31.92.3
Locomotion distance, session 30.20.20.8-0.10.10.10.2-0.40.5-0.60.70.9
Stereotopy head waving bouts, day 30.60.73.4-1.10.4-0.1-0.0-0.30.3-0.60.91.8
Stereotopy head waving duration, day 30.50.62.8-0.4-0.00.30.4-0.60.6-0.81.01.7
Locomotion velocity, session 71.01.11.9-1.10.6-0.8-1.01.3-1.31.4-1.0-0.8
Locomotion distance, session 70.81.01.6-0.90.7-0.9-1.01.2-1.21.2-0.9-0.8
Stereotopy head waving bouts, day 70.60.60.90.2-0.70.80.8-0.90.8-0.91.00.9
Stereotopy head waving duration, day 71.72.13.00.7-1.31.41.5-1.61.6-1.71.61.2
Locomotion velocity, session 81.11.32.1-0.80.9-1.1-1.21.4-1.41.5-1.2-0.7
Locomotion distance, session 81.92.73.8-1.31.5-1.7-1.72.0-2.02.0-1.5-0.8
Degree of sensitization distance0.60.61.7-0.00.1-0.3-0.50.8-0.91.0-1.0-1.3
Degree of sensitization stereotypy0.20.20.20.3-0.50.50.5-0.50.4-0.40.50.2
Conditioned locomotion1.92.23.51.8-1.11.21.4-1.71.9-1.91.40.6
Cocaine response after cond. corrected0.10.20.60.5-0.30.30.3-0.30.4-0.3-0.2-0.8
Cocaine response after cond. not corrected0.81.21.71.2-1.21.21.2-1.21.3-1.20.7-0.2
Cocaine response before conditioning1.21.41.70.7-1.21.31.3-1.31.3-1.31.21.0
Saline control response0.00.00.1-0.10.1-0.00.0-0.20.2-0.30.10.2
Bone: connectivity density0.10.20.30.6-0.0-0.1-0.20.4-0.40.6-0.4-0.5
Bone: cortical apparent density4.77.414.1-3.73.3-3.2-3.02.7-2.62.3-1.60.4
Bone: cortical area0.00.10.4-0.00.1-0.10.0-0.10.1-0.20.40.6
Bone: cortical porosity1.92.03.41.8-1.61.61.6-1.51.4-1.31.00.2
Bone: cortical porosity2.93.25.72.4-2.12.12.0-1.81.7-1.61.30.0
Bone: cortical thickness0.91.52.8-1.61.7-1.5-1.41.1-1.10.8-0.20.9
Bone: cortical thickness0.10.10.2-0.50.3-0.3-0.30.4-0.40.4-0.2-0.0
Bone: cortical tissue density4.47.013.6-3.73.3-3.1-3.02.6-2.62.2-1.50.4
Condit. Reinf. active minus inactive responses5.96.78.52.6-2.92.92.9-2.82.6-2.62.51.0
Condit. Reinf. active-inactive response ratio3.74.05.02.1-2.22.22.2-2.12.1-2.01.80.8
Condit. Reinf. active responses3.14.06.02.3-2.52.42.3-2.11.9-1.81.60.1
Condit. Reinf. inactive responses0.10.20.7-0.0-0.0-0.1-0.20.4-0.50.6-0.5-0.8
Incentive salience index mean2.02.55.02.2-2.12.01.8-1.51.3-1.21.1-0.3
Condit. Reinf. lever presses0.40.62.00.8-0.30.1-0.20.6-0.71.0-0.8-1.4
Condit. Reinf. active minus inactive responses2.33.55.32.3-2.22.22.1-1.91.9-1.71.1-0.6
Condit. Reinf. active-inactive response ratio1.62.64.32.1-1.91.81.7-1.71.6-1.50.9-0.7
Condit. Reinf. active responses0.50.81.31.1-1.11.01.0-0.80.8-0.70.1-0.9
Condit. Reinf. inactive responses0.50.71.2-0.70.4-0.6-0.70.9-1.01.0-1.1-0.8
Condit. Reinf. lever presses0.30.40.8-0.50.1-0.2-0.40.6-0.70.8-0.8-0.9
Condit. Reinf. lever reinforcers received0.40.61.21.0-1.00.80.8-0.60.6-0.4-0.2-1.1
Conditioned reinforcement - actives0.10.41.9-0.50.00.20.3-0.50.5-0.61.01.4
Conditioned reinforcement - inactives0.92.65.6-0.9-0.81.11.2-1.61.5-1.82.32.4
Conditioned locomotion0.30.51.8-1.30.9-0.6-0.50.1-0.1-0.20.51.1
Patch foraging indifference point 0 sec4.813.418.5-2.33.2-3.6-3.84.1-4.14.3-4.1-3.0
Patch foraging indifference point AUC0.10.30.3-0.20.5-0.6-0.60.6-0.60.6-0.5-0.5
Delay disc. indifference point, 0s delay1.92.13.7-0.90.9-1.1-1.41.7-1.81.9-1.8-1.2
Delay disc. indifference point, 16s delay0.71.02.1-0.20.2-0.4-0.71.1-1.31.5-1.3-1.1
Delay disc. indifference point, 2s delay1.41.52.5-0.20.7-0.9-1.11.3-1.41.5-1.6-1.6
Delay disc. indifference point, 24s delay0.10.10.2-0.30.4-0.3-0.40.3-0.40.4-0.30.2
Delay disc. indifference point, 4s delay1.31.42.0-0.81.2-1.2-1.31.4-1.41.4-1.2-0.3
Delay disc. indifference point, 8s delay0.81.42.70.00.2-0.5-0.81.3-1.41.6-1.6-1.6
Indifference point function ln k0.82.63.6-0.81.3-1.5-1.61.7-1.81.8-1.9-1.6
Indifference point function log k0.82.63.6-0.81.3-1.5-1.61.7-1.81.8-1.9-1.6
Patch foraging total patch changes 0 sec4.312.617.1-2.43.1-3.5-3.74.0-4.04.1-3.9-2.8
Patch foraging total patch changes 12 sec1.52.03.0-0.81.2-1.3-1.41.6-1.71.7-1.5-1.2
Patch foraging total patch changes 18 sec2.04.66.0-2.22.1-2.2-2.32.4-2.42.4-1.9-0.8
Patch foraging total patch changes 24 sec0.82.64.0-1.31.4-1.6-1.61.9-1.92.0-1.7-0.8
Patch foraging total patch changes 6 sec6.110.213.6-2.13.0-3.3-3.43.6-3.63.7-3.4-2.3
Patch foraging time to switch 0 sec0.93.55.30.9-1.51.71.8-1.92.0-2.02.32.2
Patch foraging water rate 0 sec0.62.44.4-1.01.2-1.4-1.51.6-1.61.6-2.1-1.7
Patch foraging water rate 12 sec0.62.55.0-0.41.0-1.3-1.41.6-1.61.8-2.1-2.2
Patch foraging water rate 18 sec0.10.21.00.5-0.10.00.0-0.10.1-0.1-0.5-1.0
Patch foraging water rate 24 sec0.30.40.70.6-0.60.60.7-0.80.8-0.8-0.1-0.4
Patch foraging water rate 6 sec1.21.82.5-0.71.3-1.4-1.51.5-1.51.5-1.6-1.0
Seeking ratio, delayed vs. immediate footshock1.72.43.21.6-1.81.81.8-1.61.6-1.51.30.6
Distance traveled before self-admin2.35.07.52.4-2.72.72.6-2.42.3-2.21.5-0.1
Distance traveled after self-admin0.61.12.41.3-1.51.41.1-0.90.7-0.60.2-0.9
Extensor digitorum longus weight2.07.813.4-3.53.7-3.4-3.22.8-2.62.2-1.70.5
Bone: elastic displacement0.20.30.70.2-0.40.50.5-0.70.7-0.80.60.2
Bone: elastic work1.21.62.11.4-1.41.41.4-1.31.3-1.21.10.1
Bone: endosteal estimation2.05.010.13.2-2.92.72.5-2.12.0-1.71.0-0.9
Bone: endosteal perimeter1.43.44.52.1-2.12.12.1-2.02.0-1.91.2-0.1
Epididymis fat weight0.41.93.51.9-1.41.41.4-1.51.5-1.41.1-0.0
Delta time in closed arm before/after self-admin0.40.40.6-0.20.8-0.7-0.70.7-0.70.7-0.30.2
Delta time in open arm before/after self-admin2.63.18.62.9-2.22.01.9-1.51.4-1.11.1-0.2
Diff in mean of infusions in LGA sessions0.20.30.70.5-0.80.80.6-0.50.4-0.30.2-0.6
Delay discount exponential model param1.62.23.90.6-0.91.21.4-1.71.9-2.01.81.2
Extinction: sum of active levers before priming0.71.01.50.5-1.21.21.2-1.21.1-1.10.80.4
Active lever presses in extinction session 60.40.41.60.9-0.80.60.5-0.30.3-0.1-0.3-1.3
Bone: final force1.52.53.71.9-1.61.61.7-1.71.7-1.61.40.6
Bone: final moment1.01.62.51.6-1.21.31.3-1.31.4-1.31.10.5
Food consumed during 24 hour testing period0.20.30.70.4-0.80.80.7-0.50.4-0.40.50.1
Glucose0.20.31.6-0.60.4-0.2-0.1-0.10.1-0.30.81.3
Heart weight0.10.21.10.2-0.30.10.00.2-0.20.3-0.2-1.1
Delay discount hyperbolic model param1.82.34.10.7-1.01.21.5-1.81.9-2.01.91.2
Intermittent access intake day 1-15 change0.21.12.3-1.51.1-1.1-1.11.0-1.00.9-1.0-0.1
Intermittent access intake escalation0.31.53.4-1.91.4-1.3-1.31.1-1.11.0-1.00.1
Intermittent access intake escalation 20.61.11.3-1.11.0-1.0-1.11.1-1.11.1-1.2-0.6
Intermitt. access day 1 inactive lever presses0.22.16.9-2.61.7-1.4-1.20.6-0.60.20.72.0
Intermitt. access day 15 inactive lever presses0.10.41.3-1.10.6-0.6-0.60.6-0.70.5-0.20.1
Intermitt. access escalation Index0.00.10.3-0.30.3-0.20.0-0.30.5-0.60.50.3
Intermittent access day 1 total infusions0.10.20.60.3-0.30.40.4-0.50.5-0.60.80.5
Intermittent access day 15 total infusions0.40.93.0-1.71.2-0.9-0.70.3-0.3-0.00.41.5
Intermittent access terminal intake (last 3 days)0.81.33.5-1.91.6-1.4-1.20.8-0.80.5-0.11.0
Intermittent access total infusions0.40.41.9-0.60.4-0.10.1-0.40.4-0.70.91.4
Intermittent access day 1 locomotion0.00.10.1-0.20.3-0.3-0.30.3-0.30.3-0.1-0.1
Intermittent access day 15 total locomotion0.10.51.0-1.00.6-0.7-0.70.8-0.80.8-0.7-0.3
Intermittent access total locomotion0.70.81.6-1.31.1-1.0-1.00.9-0.90.8-0.6-0.2
Intermittent access standard deviation0.10.63.2-1.80.8-0.6-0.60.3-0.30.1-0.00.8
Left kidney weight0.10.50.80.7-0.60.70.7-0.80.9-0.90.5-0.3
Right kidney weight0.10.92.5-0.30.6-0.7-0.80.9-0.91.0-1.1-1.6
Cocaine induced anxiety0.30.91.5-0.71.2-1.2-1.10.9-0.80.7-1.2-0.6
Post-drug Anxiety0.20.20.6-0.40.7-0.6-0.50.2-0.1-0.1-0.6-0.2
Baseline Anxiety1.01.62.01.3-1.41.41.4-1.41.3-1.31.10.5
Tail length3.418.229.75.5-4.74.74.7-4.44.4-4.03.50.8
Length with tail5.825.535.15.9-5.65.65.6-5.35.3-4.94.20.9
Length without tail1.57.910.03.0-3.23.23.2-3.13.1-2.92.30.2
Times rat made contact with spout1.51.84.0-0.1-0.60.91.0-1.31.3-1.51.92.0
Lifetime Intake0.30.31.2-0.70.7-0.5-0.3-0.10.2-0.30.61.1
Liver weight, left2.74.65.81.4-2.02.22.3-2.42.4-2.42.41.7
Liver weight, right1.93.35.11.2-1.61.71.9-2.12.2-2.32.01.1
Locomotor activity0.10.10.3-0.20.2-0.2-0.30.2-0.30.3-0.3-0.5
Locomotor testing distance0.30.83.3-0.00.3-0.4-0.60.7-0.70.8-1.4-1.8
Locomotor testing rearing0.10.30.6-0.30.7-0.6-0.60.4-0.40.3-0.7-0.8
Locomotion in novel chamber0.91.22.4-1.01.0-1.1-1.01.0-0.80.8-1.5-1.6
Locomotion in novel chamber post-restriction0.00.10.6-0.10.5-0.3-0.2-0.10.2-0.30.40.8
Fecal boli incidents, locomotor time 12.46.212.5-0.11.1-1.6-2.02.6-2.83.1-3.5-3.5
Change in fecal boli incidents, locomotor task0.20.20.40.7-0.20.20.4-0.50.6-0.60.10.1
Time >=10cm from walls, locomotor time 10.50.71.20.30.4-0.6-0.70.9-0.91.1-1.1-1.1
Bouts of movement, locomotor time 13.14.05.2-1.11.9-2.1-2.12.2-2.22.3-2.2-1.8
Total resting periods, locomotor time 13.94.55.8-1.42.0-2.2-2.32.4-2.32.4-2.2-1.7
Rest time, locomotor task time 10.81.31.9-0.51.1-1.2-1.21.3-1.31.4-1.1-0.6
Distance moved, locomotor task time 10.10.40.60.8-0.70.70.7-0.60.6-0.60.40.1
Vertical activity count, locomotor time 10.10.81.20.1-0.60.80.8-0.90.9-1.01.11.1
Time >=10cm from walls, locomotor time 20.41.14.12.0-1.21.00.9-0.60.6-0.4-0.1-1.2
Bouts of movement, locomotor time 21.13.65.1-2.12.3-2.2-2.22.0-1.91.7-1.5-0.7
Total resting periods, locomotor time 21.14.45.9-2.32.4-2.4-2.42.2-2.12.0-1.6-0.8
Rest time, locomotor task time 20.40.71.6-1.21.3-1.1-1.00.8-0.60.60.00.5
Distance moved, locomotor task time 20.20.30.90.9-0.80.60.5-0.30.2-0.1-0.1-0.7
Vertical activity count, locomotor time 20.00.00.1-0.2-0.10.20.2-0.20.2-0.20.20.4
Light reinforcement 10.73.05.7-2.12.4-2.2-2.01.7-1.61.3-0.70.9
Light reinforcement 20.10.30.5-0.30.7-0.6-0.60.5-0.50.4-0.10.6
Bone: marrow area1.94.79.43.1-2.82.62.4-2.12.0-1.61.0-0.9
Bone: maximum diameter0.10.10.30.4-0.20.20.3-0.50.5-0.50.30.1
Bone: maximum force1.42.85.42.3-1.91.91.9-1.71.7-1.51.30.3
Bone: maximum moment0.91.73.71.9-1.51.41.4-1.31.3-1.10.90.2
Mean time between licks in bursts0.21.23.0-1.71.4-1.3-1.20.9-0.90.6-0.40.5
Mean num. licks in bursts0.10.10.6-0.3-0.0-0.0-0.10.2-0.40.30.50.8
Cd content in liver1.11.32.10.8-1.41.41.3-1.21.1-1.11.00.4
Co content in liver0.40.51.40.10.1-0.3-0.60.9-1.11.2-0.5-0.8
Cu content in liver0.30.31.41.2-0.70.60.5-0.40.4-0.2-0.1-0.4
Fe content in liver1.21.42.01.2-1.41.41.3-1.21.0-1.01.30.8
K content in liver1.51.52.4-1.01.2-1.2-1.31.4-1.51.6-1.1-0.1
Mg content in liver0.20.20.3-0.50.5-0.5-0.50.5-0.40.5-0.40.1
Mn content in liver0.50.51.9-1.40.8-0.7-0.70.6-0.70.5-0.30.2
Na content in liver1.31.53.0-0.10.5-0.8-1.01.3-1.41.5-1.7-1.7
Rb content in liver0.60.71.5-1.21.1-1.0-0.90.7-0.70.6-0.50.3
Se content in liver0.00.00.10.3-0.10.10.2-0.20.2-0.30.20.0
Sr content in liver0.20.20.3-0.10.5-0.5-0.50.5-0.50.5-0.30.1
Zn content in liver0.00.00.00.00.1-0.1-0.10.00.00.0-0.1-0.2
Bone: minimum diameter0.50.91.51.2-1.01.01.0-1.00.9-0.80.70.2
Time in familiar zone, hab. session 10.40.41.5-1.20.8-0.7-0.70.4-0.40.2-0.40.2
Time in novel zone, hab. session 12.12.45.42.3-2.01.81.7-1.41.3-1.00.8-0.8
Total zone transitions, hab. session 10.10.10.20.3-0.40.30.10.2-0.30.4-0.1-0.5
Total locomotion distance, hab. session 10.50.71.51.0-1.21.10.9-0.60.6-0.40.4-0.6
Locomotion velocity, hab. session 10.20.20.50.6-0.70.60.5-0.40.3-0.30.4-0.1
Time in familiar zone, hab. session 20.20.20.80.3-0.20.20.2-0.20.3-0.3-0.6-0.9
Time in novel zone, hab. session 20.30.41.30.1-0.20.20.3-0.40.4-0.51.11.1
Total zone transitions, hab. session 20.10.10.3-0.10.1-0.2-0.30.5-0.60.60.00.3
Total locomotion distance, hab. session 20.81.01.31.0-1.11.11.1-1.00.9-0.91.20.8
Locomotion velocity, hab. session 20.40.60.80.7-0.90.80.9-0.70.7-0.60.90.6
Novel to familiar place preference ratio2.43.14.31.8-1.61.71.8-1.81.9-1.82.11.4
Novelty place preference2.43.04.71.6-1.41.61.7-1.81.9-1.82.21.6
Time in novel zone, NPP test3.23.86.11.7-1.61.81.9-2.12.1-2.12.51.8
Total zone transitions, NPP test0.40.60.9-0.70.7-0.8-0.81.0-1.01.0-0.6-0.1
Total locomotion distance, NPP test0.10.10.50.7-0.50.30.3-0.0-0.00.1-0.0-0.5
Locomotion velocity, NPP test0.10.10.20.3-0.0-0.1-0.10.3-0.30.4-0.3-0.5
Intraocular pressure0.30.51.3-1.10.8-0.8-0.70.6-0.50.4-0.4-0.0
Delta distance traveled before/after self-admin0.50.60.9-0.90.8-0.8-0.80.9-0.90.9-0.4-0.1
Delta ambulatory time before/after self-admin0.81.42.0-1.01.0-1.1-1.21.3-1.41.4-1.2-0.9
Parametrial fat weight0.10.10.3-0.50.5-0.4-0.2-0.00.2-0.30.30.5
Pavlov. Cond. lever latency1.01.35.4-1.61.1-0.7-0.4-0.10.2-0.51.12.3
Pavlov. Cond. magazine entry latency1.21.64.91.8-1.61.21.0-0.40.30.1-0.6-2.2
Pavlov. Cond. change in total contacts0.70.82.61.3-1.10.70.50.1-0.20.5-0.7-1.6
Pavlov. Cond. index score1.01.35.21.6-1.30.90.6-0.10.00.3-0.9-2.3
Pavlov. Cond. latency score1.31.77.01.8-1.41.00.7-0.10.00.4-1.1-2.6
Pavlov. Cond. lever contacts0.81.04.51.4-0.90.60.40.1-0.20.5-1.0-2.1
Pavlov. Cond. magazine entry number1.62.04.3-2.12.0-1.7-1.51.0-1.00.6-0.01.6
Pavlov. Cond. intertrial magazine entries1.82.24.90.3-0.50.91.1-1.61.6-1.92.02.2
Pavlov. Cond. lever-magazine prob. diff.1.01.24.91.5-1.20.80.6-0.1-0.00.4-0.9-2.2
Pavlov. Cond. response bias0.91.23.21.7-1.41.10.9-0.30.30.1-0.5-1.8
Pavlov. Cond. lever latency0.40.51.10.40.00.20.4-0.70.9-1.01.01.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.2-0.40.40.4-0.30.1-0.20.50.6
Pavlov. Cond. change in total contacts0.10.31.10.3-0.50.30.00.4-0.50.7-0.7-1.1
Pavlov. Cond. index score0.10.10.3-0.3-0.40.20.00.3-0.40.5-0.4-0.5
Pavlov. Cond. latency score0.00.10.2-0.1-0.40.30.10.1-0.30.4-0.2-0.3
Pavlov. Cond. lever contacts0.40.61.9-0.2-0.2-0.0-0.30.7-0.81.0-1.0-1.4
Pavlov. Cond. magazine entry number0.20.20.4-0.10.6-0.6-0.50.4-0.30.3-0.6-0.5
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.50.8-0.7-0.50.2-0.1-0.0-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.5-0.20.0-0.10.4-0.50.5-0.4-0.3
Pavlov. Cond. response bias0.10.20.70.1-0.80.60.4-0.1-0.10.2-0.1-0.5
Time in closed arm before self-admin0.91.63.21.8-1.71.61.4-1.21.1-0.90.4-0.7
Time in closed arm after self-admin0.60.72.20.8-0.20.0-0.20.6-0.70.9-1.1-1.5
Time in open arm before self-admin1.11.35.0-2.21.4-1.0-0.80.2-0.1-0.40.61.6
Time in open arm after self-admin2.62.84.02.0-2.01.91.9-1.71.7-1.51.50.6
Bone: periosteal estimation1.22.95.32.3-2.02.01.9-1.71.7-1.51.1-0.2
Bone: periosteal perimeter1.01.92.51.5-1.41.51.5-1.61.6-1.51.10.3
Bone: post-yield work0.61.11.81.3-1.21.21.2-1.11.1-1.00.70.1
Progressive ratio test 1 active lever presses0.40.81.5-1.01.2-1.1-1.00.8-0.80.6-0.30.5
Progressive ratio test 1 breakpoint0.30.50.9-0.71.0-0.9-0.80.7-0.60.5-0.20.3
Progressive ratio test 1 inactive lever presses0.82.17.0-2.61.7-1.3-1.10.7-0.70.20.72.1
Progressive ratio test 2 active lever presses0.30.41.9-0.80.5-0.3-0.2-0.10.2-0.40.91.4
Progressive ratio test 2 breakpoint0.40.52.0-0.90.6-0.4-0.2-0.10.1-0.40.91.4
Progressive ratio test 2 inactive lever presses0.41.34.8-1.20.20.20.4-0.80.8-1.21.62.2
Incentive Sensitization - Responses0.30.91.50.1-0.60.80.9-1.11.1-1.21.21.0
Incentive Sensitization - Breakpoint0.41.01.80.0-0.50.70.8-1.11.1-1.31.31.2
Sum of active levers in priming session hrs 5-63.13.04.71.7-2.22.12.0-1.91.8-1.71.0-0.3
Progressive ratio0.10.21.1-0.10.2-0.10.1-0.20.2-0.30.51.1
Food seeking constrained by brief footshock0.20.21.01.0-0.20.30.3-0.30.4-0.30.40.4
Seeking ratio, punishment vs. effort0.00.10.70.3-0.20.10.10.0-0.10.1-0.3-0.8
Retroperitoneal fat weight0.10.41.4-0.40.3-0.10.1-0.30.4-0.51.01.2
Reaction time number correct0.31.14.4-1.30.8-0.5-0.1-0.40.5-0.91.22.1
Reaction time mean minus median0.42.74.62.2-2.01.91.8-1.71.6-1.40.8-0.9
Reaction time mean minus median AUC0.32.33.51.9-1.81.71.7-1.61.6-1.40.7-0.8
Reaction time num false alarms2.33.97.6-2.72.4-2.2-2.21.9-1.91.7-1.10.5
Reaction time num false alarms AUC1.63.68.5-2.92.3-2.1-2.11.8-1.81.4-0.90.8
Reaction time trials correct on left0.31.14.4-1.30.8-0.5-0.1-0.40.5-0.91.22.1
Reaction time trials on left0.31.14.7-1.20.7-0.4-0.0-0.50.7-1.01.32.2
Reaction time mean4.910.915.33.9-3.73.73.7-3.63.6-3.32.3-0.2
Reaction time mean AUC4.410.513.83.7-3.63.63.6-3.63.6-3.42.3-0.2
Median of all reaction times7.111.115.63.9-3.73.73.7-3.63.7-3.42.40.0
Reaction time omissions1.21.93.21.3-1.11.31.4-1.71.8-1.81.20.5
Reaction time false alarm rate2.23.14.0-2.01.8-1.8-1.91.9-2.01.9-1.5-0.4
Reaction time premature initiation rate0.81.34.90.10.4-0.6-0.80.9-1.01.1-1.7-2.2
Reaction time premature initiations0.10.40.8-0.60.7-0.7-0.70.5-0.50.4-0.9-0.8
Std. dev. reaction times2.27.210.63.2-3.33.13.0-2.82.8-2.51.6-0.8
Reaction time trials completed0.31.14.7-1.20.7-0.4-0.0-0.50.7-1.01.32.2
Reaction time trials AUC0.31.04.5-1.20.8-0.4-0.1-0.40.6-0.91.22.1
Run reversals in cocaine runway, females1.11.21.70.9-0.81.01.1-1.21.3-1.31.11.1
Run reversals in cocaine runway, males0.20.20.4-0.60.6-0.5-0.50.3-0.30.2-0.3-0.4
Latency to leave start box in cocaine runway3.54.810.2-3.22.6-2.5-2.42.2-2.21.9-1.40.2
Latency to leave start box in cocaine runway, F1.82.36.7-2.61.9-1.7-1.61.3-1.20.9-0.60.4
Latency to leave start box in cocaine runway, M4.34.15.6-2.01.9-2.1-2.12.3-2.32.4-1.8-0.7
Std. dev. time between licks in bursts2.03.76.6-2.32.6-2.4-2.21.9-1.81.6-1.20.3
Total sessions with >9 infusions1.11.42.9-1.71.6-1.5-1.31.0-0.90.7-0.70.2
Short access day 1 total inactive lever presses0.30.61.9-0.70.20.10.2-0.60.6-0.91.11.4
Short access day 10 total inactive lever presses0.10.72.7-1.30.20.10.1-0.40.3-0.61.11.6
Short access day 1 total infusions0.10.21.0-1.00.8-0.6-0.50.2-0.1-0.1-0.10.1
Short access day 10 total infusions0.40.61.8-0.91.3-1.1-0.90.5-0.40.20.10.5
Short access total infusions0.30.41.0-0.71.0-1.0-0.80.6-0.50.4-0.30.0
Short access day 1 locomotion0.20.41.3-1.10.8-0.7-0.40.2-0.0-0.10.31.0
Short access day 10 total locomotion0.52.12.8-1.61.3-1.4-1.51.6-1.71.6-1.3-1.0
Short access total locomotion0.60.93.6-1.91.3-1.1-0.90.5-0.50.20.10.9
One hour access (0.3 mA shock)0.10.10.2-0.20.4-0.4-0.40.4-0.40.4-0.10.1
Compulsive drug intake0.20.20.3-0.40.5-0.5-0.50.5-0.50.5-0.5-0.5
One hour access (shock baseline)0.10.20.50.3-0.10.20.3-0.40.5-0.50.70.7
Social response proportion1.01.33.11.8-1.31.21.1-1.01.0-0.80.2-1.1
Social responses0.20.32.10.5-0.30.20.1-0.10.1-0.0-0.5-1.5
Social time0.81.32.61.6-1.11.11.1-1.11.2-1.10.6-0.7
Soleus weight0.30.91.4-0.31.1-1.2-1.11.1-0.91.0-1.2-0.6
Bone: stiffness0.81.43.21.8-1.51.41.3-1.11.0-0.80.90.2
Tibialis anterior weight1.13.87.2-2.22.7-2.5-2.32.0-1.81.6-1.10.5
Time to tail flick, vehicle, before self-admin0.40.50.8-0.60.7-0.7-0.80.8-0.90.8-0.4-0.1
Time to tail flick, vehicle, after self-admin0.00.10.1-0.40.0-0.0-0.20.3-0.40.4-0.00.4
Time to tail flick, test, before self-admin0.40.51.5-1.20.8-0.5-0.40.1-0.1-0.20.61.2
Time to tail flick, test, after self-admin0.40.40.8-0.90.9-0.8-0.70.6-0.50.4-0.30.4
Delta time to tail flick, vehicle, before/after SA0.00.00.10.1-0.30.20.2-0.10.00.00.10.3
Delta time to tail flick, test, before/after SA0.50.61.70.70.0-0.2-0.30.6-0.60.8-1.2-1.3
Tibia length3.59.714.93.9-3.63.63.5-3.23.2-2.92.30.1
Ambulatory time before self-admin2.06.08.12.2-2.82.92.8-2.72.6-2.62.00.5
Ambulatory time after self-admin0.30.52.20.6-0.80.60.3-0.0-0.20.3-0.6-1.5
Bone: tissue strength0.20.20.70.8-0.30.30.4-0.40.5-0.50.40.4
Total heroin consumption0.30.40.80.7-0.90.80.7-0.50.5-0.4-0.1-0.6
Bone: trabecular number0.20.41.81.3-0.80.60.4-0.10.00.2-0.3-0.8
Bone: trabecular spacing0.10.20.4-0.40.1-0.2-0.30.5-0.50.6-0.5-0.6
Bone: trabecular thickness0.40.51.81.3-1.10.90.7-0.30.20.00.2-0.6
Bone: trabecular tissue density0.10.20.30.1-0.60.50.5-0.40.4-0.40.50.3
Water consumed over 24 hours0.10.20.7-0.80.2-0.1-0.1-0.0-0.0-0.20.40.8
Number of responses in last shaping day0.30.41.6-1.30.5-0.3-0.2-0.10.1-0.40.41.0