Hub : Genes

Mrtfa

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Mrtfa 0.03 0.02 8.9e-03 0 0.01 0.01 0 1.0e-01 1.6e-02 6.1e-02 7.2e-02
2 IL gene expression Mrtfa 0.34 0.14 1.6e-05 0.23 0.15 0.22 0.2 2.4e-06 2.2e-04 4.4e-06 1.8e-05
3 BLA gene expression Mrtfa 0.28 0.11 1.3e-11 0.17 0.18 0.17 0.17 3.0e-09 6.8e-10 2.0e-09 1.5e-09
4 Brain gene expression Mrtfa 0.12 0.06 1.3e-09 0.1 0.11 0.09 0.11 1.4e-09 1.7e-10 9.8e-09 3.5e-10
5 PL gene expression Mrtfa 0.16 0.07 0.0e+00 0.17 0.18 0.18 0.18 2.5e-18 2.5e-19 3.1e-19 4.5e-19
6 Brain mRNA stability Mrtfa 0.04 0.02 6.3e-04 0.06 0.04 0.04 0.05 7.4e-06 1.4e-04 7.1e-05 1.5e-05
7 OFC gene expression Mrtfa 0.39 0.15 6.6e-07 0.29 0.17 0.32 0.23 1.6e-07 8.1e-05 2.8e-08 2.9e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.20.1-0.30.40.40.40.1-0.1
Area under the delay curve0.60.71.3-0.3-1.00.71.10.90.5-1.0
BMI with tail0.30.93.0-1.7-1.11.10.40.70.6-0.2
BMI without tail0.00.10.30.20.0-0.0-0.4-0.10.10.5
Body weight0.52.06.2-2.5-1.51.30.80.91.1-0.9
Weight adjusted by age0.50.61.50.31.2-0.7-0.7-0.9-0.50.5
Bone surface0.20.40.9-0.2-0.60.60.90.8-0.0-0.8
Bone volume0.10.20.3-0.2-0.50.40.50.5-0.0-0.4
Breakpoint value in progressive ratio session0.30.30.5-0.2-0.70.60.50.60.7-0.5
Number of licking bursts0.30.41.90.71.4-0.3-0.0-0.2-0.30.3
Context. condit. distance diff. score1.41.62.9-0.70.9-1.3-1.7-1.7-0.81.4
Locomotion velocity, session 10.70.81.7-0.6-0.80.71.20.90.4-1.3
Locomotion distance, session 10.40.51.30.6-0.30.31.20.80.0-1.1
Locomotion velocity, session 20.30.40.4-0.7-0.60.60.60.60.6-0.6
Locomotion distance, session 22.02.84.6-0.1-1.31.62.11.91.7-1.9
Locomotion velocity, session 31.51.82.30.71.4-1.4-1.4-1.5-1.51.2
Locomotion distance, session 32.02.23.21.61.8-1.7-1.1-1.5-1.61.0
Stereotopy head waving bouts, day 31.31.52.2-1.5-1.51.31.11.21.0-0.9
Stereotopy head waving duration, day 31.51.84.0-2.0-1.61.30.91.11.2-0.8
Locomotion velocity, session 70.10.10.2-0.10.3-0.4-0.4-0.5-0.30.4
Locomotion distance, session 70.40.51.0-0.5-0.60.50.80.61.0-0.7
Stereotopy head waving bouts, day 70.20.20.5-0.60.2-0.4-0.7-0.6-0.30.4
Stereotopy head waving duration, day 70.91.12.3-0.00.8-1.1-1.5-1.3-1.11.0
Locomotion velocity, session 81.11.32.3-1.5-1.01.00.90.91.5-1.0
Locomotion distance, session 80.30.40.70.00.6-0.7-0.8-0.8-0.20.7
Degree of sensitization distance2.72.74.1-2.0-1.91.71.21.52.0-1.1
Degree of sensitization stereotypy0.70.81.3-0.00.8-1.0-1.1-1.2-0.90.7
Conditioned locomotion0.10.10.1-0.20.1-0.3-0.4-0.3-0.10.2
Cocaine response after cond. corrected0.10.20.2-0.4-0.50.40.40.40.50.3
Cocaine response after cond. not corrected0.10.10.2-0.1-0.20.10.00.10.30.5
Cocaine response before conditioning0.40.50.80.90.8-0.7-0.8-0.7-0.60.5
Saline control response1.72.22.51.31.5-1.6-1.6-1.5-1.41.4
Bone: connectivity density0.10.20.3-0.2-0.50.50.50.50.3-0.2
Bone: cortical apparent density0.81.11.91.21.4-1.0-0.8-1.0-0.91.0
Bone: cortical area1.42.03.5-1.9-1.71.51.31.31.1-1.1
Bone: cortical porosity0.20.30.6-0.7-0.80.50.20.40.50.2
Bone: cortical porosity0.91.01.8-1.3-1.31.00.60.91.1-0.2
Bone: cortical thickness0.61.01.4-1.1-1.01.21.11.10.9-0.7
Bone: cortical thickness1.72.02.8-1.3-1.41.51.51.41.7-1.1
Bone: cortical tissue density0.81.11.91.21.4-1.0-0.8-1.0-0.81.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.0-0.10.40.40.40.2-0.4
Condit. Reinf. active-inactive response ratio0.10.10.20.00.4-0.4-0.4-0.5-0.40.3
Condit. Reinf. active responses0.20.21.01.00.4-0.2-0.1-0.1-0.4-0.0
Condit. Reinf. inactive responses0.60.72.81.70.7-0.6-0.5-0.4-0.70.2
Incentive salience index mean0.10.10.20.2-0.10.40.40.40.1-0.4
Condit. Reinf. lever presses0.10.10.20.4-0.10.30.40.40.0-0.4
Condit. Reinf. active minus inactive responses1.21.52.3-0.9-1.11.31.51.30.8-1.4
Condit. Reinf. active-inactive response ratio2.22.33.2-1.3-1.41.61.61.51.3-1.8
Condit. Reinf. active responses0.81.11.5-1.1-0.91.11.21.00.7-1.2
Condit. Reinf. inactive responses0.10.20.6-0.8-0.30.30.50.30.0-0.3
Condit. Reinf. lever presses0.20.20.60.1-0.30.50.50.50.0-0.8
Condit. Reinf. lever reinforcers received0.71.01.5-1.0-0.91.11.21.00.7-1.2
Conditioned reinforcement - actives0.20.21.2-0.3-1.10.00.40.10.2-0.4
Conditioned reinforcement - inactives0.80.91.7-0.3-0.91.11.31.30.6-0.8
Conditioned locomotion2.32.83.9-2.0-1.91.71.61.51.7-1.2
Patch foraging indifference point 0 sec0.20.30.50.2-0.40.70.50.70.6-0.3
Patch foraging indifference point AUC0.40.51.4-0.4-0.50.61.20.80.3-0.6
Delay disc. indifference point, 0s delay1.01.01.9-1.2-0.91.10.91.11.4-0.5
Delay disc. indifference point, 16s delay0.40.40.90.3-0.70.40.90.7-0.0-0.9
Delay disc. indifference point, 2s delay0.80.91.3-0.8-1.10.91.11.00.9-0.7
Delay disc. indifference point, 24s delay1.00.92.1-0.8-0.90.91.51.00.3-1.1
Delay disc. indifference point, 4s delay1.41.52.4-0.8-1.11.31.51.41.3-1.0
Delay disc. indifference point, 8s delay0.40.40.90.2-0.90.30.70.50.1-0.9
Indifference point function ln k0.40.61.6-0.00.6-0.7-1.3-1.0-0.40.6
Indifference point function log k0.40.61.6-0.00.6-0.7-1.3-1.0-0.40.6
Patch foraging total patch changes 0 sec0.20.30.40.2-0.40.70.50.70.6-0.4
Patch foraging total patch changes 12 sec0.50.61.0-0.6-0.80.91.00.90.5-0.7
Patch foraging total patch changes 18 sec2.12.73.7-1.0-1.71.81.91.91.5-1.5
Patch foraging total patch changes 24 sec0.20.30.6-0.0-0.50.50.80.70.3-0.3
Patch foraging total patch changes 6 sec2.33.45.2-1.0-1.82.12.32.21.7-1.5
Patch foraging time to switch 0 sec0.10.10.3-0.1-0.50.2-0.00.30.40.1
Patch foraging water rate 0 sec0.10.20.3-0.1-0.30.60.50.50.4-0.3
Patch foraging water rate 12 sec0.30.51.11.00.8-0.6-0.6-0.6-0.70.5
Patch foraging water rate 18 sec0.20.30.60.4-0.20.50.70.6-0.1-0.8
Patch foraging water rate 24 sec0.00.00.0-0.1-0.00.2-0.00.0-0.1-0.2
Patch foraging water rate 6 sec1.52.33.41.81.7-1.5-1.3-1.4-1.70.9
Seeking ratio, delayed vs. immediate footshock0.50.62.81.11.7-0.10.00.0-0.20.0
Distance traveled before self-admin0.20.20.5-0.1-0.40.40.40.50.7-0.2
Distance traveled after self-admin3.23.55.0-1.3-1.62.22.12.12.2-1.3
Extensor digitorum longus weight0.10.61.11.00.6-0.6-0.7-0.5-0.70.9
Bone: elastic displacement0.10.10.20.10.2-0.3-0.2-0.3-0.40.1
Bone: elastic work1.72.23.6-1.9-1.71.51.11.31.5-1.1
Bone: endosteal estimation0.61.22.1-1.3-1.40.90.91.00.7-1.2
Bone: endosteal perimeter0.30.62.0-1.4-1.10.50.30.40.3-0.6
Epididymis fat weight0.20.52.0-1.4-0.1-0.6-0.8-0.8-0.20.3
Delta time in closed arm before/after self-admin0.30.31.0-1.0-0.50.50.40.30.6-0.3
Delta time in open arm before/after self-admin0.20.20.50.70.4-0.4-0.2-0.2-0.50.3
Diff in mean of infusions in LGA sessions0.70.71.1-0.7-0.80.91.00.80.8-0.9
Delay discount exponential model param0.60.61.10.20.9-0.6-1.1-0.8-0.41.0
Extinction: sum of active levers before priming0.40.41.1-0.4-0.20.60.70.71.1-0.7
Active lever presses in extinction session 60.20.20.3-0.50.50.50.40.50.6-0.4
Bone: final force3.55.77.8-2.8-2.62.52.32.32.1-2.1
Bone: final moment3.96.38.4-2.9-2.72.62.42.42.2-2.2
Food consumed during 24 hour testing period2.32.84.2-2.1-1.41.71.51.51.9-1.6
Glucose0.00.00.20.4-0.20.20.00.30.10.1
Heart weight0.60.81.5-1.2-1.00.90.30.71.2-0.3
Delay discount hyperbolic model param0.70.71.30.31.1-0.7-1.2-0.9-0.61.0
Intermittent access intake day 1-15 change0.40.41.01.0-0.2-0.7-0.6-0.7-0.50.4
Intermittent access intake escalation0.30.30.91.0-0.3-0.6-0.5-0.5-0.50.3
Intermittent access intake escalation 20.20.20.50.7-0.4-0.4-0.4-0.3-0.5-0.1
Intermitt. access day 1 inactive lever presses1.21.32.6-1.0-0.51.41.11.31.6-0.6
Intermitt. access day 15 inactive lever presses1.01.11.7-1.0-0.61.31.31.20.9-0.8
Intermitt. access escalation Index0.10.10.20.00.40.30.00.10.4-0.2
Intermittent access day 1 total infusions1.31.52.0-1.4-1.31.21.31.21.1-0.8
Intermittent access day 15 total infusions0.70.82.2-0.4-1.50.80.90.90.7-0.7
Intermittent access terminal intake (last 3 days)0.20.20.9-0.2-1.00.20.30.20.1-0.3
Intermittent access total infusions1.31.52.2-1.2-1.51.21.31.21.1-0.9
Intermittent access day 1 locomotion1.01.11.8-1.1-1.31.11.01.10.9-0.5
Intermittent access day 15 total locomotion0.60.72.0-0.8-1.40.80.80.80.6-0.2
Intermittent access total locomotion1.82.03.9-1.5-2.01.41.41.41.2-0.8
Intermittent access standard deviation1.01.13.5-0.9-1.90.90.70.90.8-0.7
Left kidney weight1.95.421.5-4.6-2.11.81.01.02.1-1.4
Right kidney weight3.29.128.2-5.3-3.02.61.91.92.7-2.2
Cocaine induced anxiety0.60.72.1-1.5-0.60.90.40.70.7-0.4
Post-drug Anxiety0.60.71.1-1.0-0.61.00.60.71.1-0.6
Baseline Anxiety0.30.31.61.20.3-0.6-0.2-0.4-0.50.0
Tail length0.10.40.80.90.6-0.7-0.7-0.6-0.20.4
Length with tail0.10.31.0-1.0-0.40.30.20.10.5-0.5
Length without tail0.61.34.0-2.0-1.01.01.00.80.8-1.0
Times rat made contact with spout0.50.61.2-1.10.10.90.90.80.7-0.4
Lifetime Intake2.52.83.1-1.8-1.71.71.71.71.7-1.4
Liver weight, left0.50.81.30.10.7-1.0-1.1-1.1-0.90.8
Liver weight, right2.23.76.00.31.7-2.1-2.4-2.4-1.91.6
Locomotor activity0.10.21.2-1.1-0.50.30.00.1-0.10.0
Locomotor testing distance0.20.40.70.40.6-0.5-0.5-0.6-0.80.7
Locomotor testing rearing0.10.10.5-0.7-0.1-0.1-0.3-0.30.10.5
Locomotion in novel chamber4.35.38.62.91.9-2.5-2.3-2.3-2.31.5
Locomotion in novel chamber post-restriction0.60.71.41.20.6-0.9-0.8-0.8-0.70.6
Fecal boli incidents, locomotor time 11.41.52.3-0.7-1.21.31.51.41.1-1.2
Change in fecal boli incidents, locomotor task0.40.40.80.10.7-0.8-0.6-0.9-0.50.1
Time >=10cm from walls, locomotor time 10.70.71.1-1.0-0.30.90.80.81.1-0.6
Bouts of movement, locomotor time 10.30.31.0-1.00.70.30.40.30.6-0.1
Total resting periods, locomotor time 10.40.41.1-1.10.40.60.60.60.7-0.4
Rest time, locomotor task time 11.11.22.4-1.1-1.51.00.91.01.1-0.9
Distance moved, locomotor task time 10.60.61.20.40.4-0.9-1.1-1.0-0.60.8
Vertical activity count, locomotor time 10.00.00.10.00.10.1-0.00.10.3-0.3
Time >=10cm from walls, locomotor time 20.40.40.6-0.40.00.80.70.70.7-0.6
Bouts of movement, locomotor time 20.20.20.5-0.40.60.2-0.00.00.40.7
Total resting periods, locomotor time 20.20.20.5-0.70.10.60.40.40.60.2
Rest time, locomotor task time 20.30.41.3-0.2-1.10.40.60.50.3-0.5
Distance moved, locomotor task time 20.30.40.90.10.2-0.7-0.9-0.8-0.30.7
Vertical activity count, locomotor time 20.30.30.7-0.5-0.70.30.30.40.9-0.4
Light reinforcement 10.00.00.00.0-0.10.10.20.20.1-0.1
Light reinforcement 20.71.01.80.20.9-1.0-1.4-1.2-0.90.8
Bone: marrow area0.61.42.3-1.4-1.51.01.01.10.8-1.3
Bone: maximum diameter2.54.68.6-2.9-2.52.11.71.82.0-1.8
Bone: maximum force4.88.211.5-3.4-3.22.92.72.82.6-2.3
Bone: maximum moment5.18.812.2-3.5-3.33.02.82.92.7-2.4
Mean time between licks in bursts0.40.61.31.01.2-0.5-0.6-0.5-0.60.5
Mean num. licks in bursts0.40.51.7-1.3-1.00.50.30.30.4-0.5
Cd content in liver0.30.30.80.1-0.0-0.7-0.9-0.9-0.40.3
Co content in liver0.30.40.8-0.70.20.70.50.60.9-0.5
Cu content in liver0.30.42.21.50.1-0.20.00.1-0.50.1
Fe content in liver0.10.20.6-0.20.00.40.20.50.80.1
K content in liver0.20.20.30.20.00.50.50.50.4-0.4
Mg content in liver0.40.40.70.2-0.60.80.80.90.3-0.5
Mn content in liver0.50.51.20.40.5-0.8-0.7-0.9-1.10.4
Na content in liver0.20.21.31.10.3-0.20.00.1-0.40.1
Rb content in liver0.40.50.8-0.50.10.70.90.80.9-0.5
Se content in liver1.62.02.71.70.6-1.6-1.4-1.5-1.71.1
Sr content in liver1.21.11.71.30.5-1.2-1.0-1.1-1.00.8
Zn content in liver0.40.51.51.00.5-0.5-0.4-0.4-1.20.1
Bone: minimum diameter0.61.01.8-1.2-1.40.90.91.00.5-1.0
Time in familiar zone, hab. session 11.00.91.4-0.9-0.90.81.20.90.6-1.2
Time in novel zone, hab. session 10.60.51.30.30.6-0.6-1.1-0.80.01.1
Total zone transitions, hab. session 11.62.24.72.21.8-1.5-0.7-1.2-1.70.6
Total locomotion distance, hab. session 12.02.94.62.21.9-1.8-1.3-1.6-1.81.0
Locomotion velocity, hab. session 11.21.73.81.91.5-1.4-0.8-1.0-1.40.6
Time in familiar zone, hab. session 22.12.23.71.11.4-1.5-1.6-1.6-1.91.1
Time in novel zone, hab. session 21.81.83.4-1.0-1.21.41.41.41.9-1.0
Total zone transitions, hab. session 21.01.42.8-0.2-0.91.21.71.40.7-1.4
Total locomotion distance, hab. session 20.40.61.10.2-0.60.81.01.00.6-0.9
Locomotion velocity, hab. session 20.50.71.40.3-0.60.81.21.10.6-1.0
Novel to familiar place preference ratio0.20.20.4-0.70.1-0.3-0.5-0.50.00.2
Novelty place preference0.30.30.6-0.70.3-0.5-0.8-0.8-0.20.4
Time in novel zone, NPP test0.30.30.8-0.90.2-0.5-0.8-0.7-0.10.3
Total zone transitions, NPP test0.71.02.81.71.1-0.7-0.0-0.5-1.40.1
Total locomotion distance, NPP test0.20.20.90.90.4-0.20.30.0-0.6-0.3
Locomotion velocity, NPP test0.30.51.91.40.7-0.5-0.0-0.2-0.80.0
Intraocular pressure0.00.00.2-0.4-0.0-0.20.0-0.20.3-0.1
Delta distance traveled before/after self-admin1.31.42.0-1.2-1.11.31.41.21.1-0.8
Delta ambulatory time before/after self-admin2.22.43.5-1.5-1.41.71.91.71.5-1.3
Parametrial fat weight0.00.00.1-0.20.1-0.1-0.2-0.10.30.3
Pavlov. Cond. lever latency0.10.10.5-0.7-0.30.1-0.0-0.00.4-0.0
Pavlov. Cond. magazine entry latency0.30.40.8-0.1-0.50.80.90.80.3-0.6
Pavlov. Cond. change in total contacts1.41.52.5-0.3-1.01.41.61.50.9-1.4
Pavlov. Cond. index score0.30.40.7-0.3-0.60.80.90.80.3-0.6
Pavlov. Cond. latency score0.10.20.4-0.1-0.40.60.60.60.1-0.4
Pavlov. Cond. lever contacts0.10.10.30.6-0.00.20.30.3-0.2-0.1
Pavlov. Cond. magazine entry number0.10.10.3-0.00.1-0.4-0.5-0.40.10.3
Pavlov. Cond. intertrial magazine entries0.50.60.90.1-0.60.70.90.90.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.1-0.30.60.70.6-0.0-0.5
Pavlov. Cond. response bias0.20.30.6-0.0-0.40.70.80.70.3-0.6
Pavlov. Cond. lever latency0.10.20.5-0.50.1-0.5-0.3-0.50.00.7
Pavlov. Cond. magazine entry latency1.21.42.20.2-0.91.31.41.41.0-1.5
Pavlov. Cond. change in total contacts3.34.66.6-1.2-2.02.52.22.41.7-2.6
Pavlov. Cond. index score0.50.71.50.4-0.51.00.91.00.3-1.2
Pavlov. Cond. latency score0.70.91.80.4-0.61.11.11.10.4-1.3
Pavlov. Cond. lever contacts0.10.20.40.6-0.00.50.20.4-0.1-0.6
Pavlov. Cond. magazine entry number0.70.92.1-0.00.7-1.0-1.1-1.1-0.61.4
Pavlov. Cond. intertrial magazine entries0.50.62.2-1.5-0.80.70.50.50.70.1
Pavlov. Cond. lever-magazine prob. diff.0.50.61.30.4-0.50.90.80.90.2-1.1
Pavlov. Cond. response bias0.60.81.70.0-0.71.10.91.10.5-1.3
Time in closed arm before self-admin1.21.32.10.7-1.31.11.11.41.0-1.1
Time in closed arm after self-admin1.51.52.4-1.1-1.51.21.01.11.5-1.1
Time in open arm before self-admin1.51.62.40.60.8-1.5-1.4-1.5-1.51.2
Time in open arm after self-admin2.12.32.61.41.5-1.6-1.5-1.5-1.61.5
Bone: periosteal estimation1.22.64.1-2.0-2.01.51.41.51.1-1.5
Bone: periosteal perimeter1.21.95.1-2.3-1.81.20.91.00.9-1.0
Bone: post-yield work2.93.94.7-1.7-2.12.12.22.12.1-1.5
Progressive ratio test 1 active lever presses2.02.13.3-1.6-1.81.41.61.51.1-1.0
Progressive ratio test 1 breakpoint0.91.02.0-1.1-1.40.91.00.90.6-0.6
Progressive ratio test 1 inactive lever presses0.80.91.3-0.9-0.81.20.91.10.9-0.6
Progressive ratio test 2 active lever presses0.60.71.3-0.7-1.10.81.10.90.5-0.6
Progressive ratio test 2 breakpoint1.01.21.8-1.0-1.31.11.31.10.9-0.7
Progressive ratio test 2 inactive lever presses0.40.51.0-0.1-0.60.71.00.90.8-0.2
Incentive Sensitization - Responses0.10.10.30.60.3-0.3-0.2-0.3-0.30.1
Incentive Sensitization - Breakpoint0.00.00.10.40.2-0.2-0.1-0.2-0.20.1
Sum of active levers in priming session hrs 5-60.00.00.00.10.1-0.0-0.2-0.0-0.10.1
Progressive ratio0.20.20.3-0.1-0.60.50.50.60.3-0.2
Food seeking constrained by brief footshock0.40.51.5-1.2-0.40.70.70.70.8-0.3
Seeking ratio, punishment vs. effort0.20.30.7-0.8-0.40.40.40.30.6-0.3
Retroperitoneal fat weight0.31.16.6-2.6-0.50.2-0.5-0.40.70.5
Reaction time number correct1.82.63.91.71.8-1.7-1.3-1.5-2.01.2
Reaction time mean minus median0.10.10.20.20.2-0.3-0.4-0.3-0.30.3
Reaction time mean minus median AUC0.30.40.80.00.4-0.6-0.9-0.7-0.50.6
Reaction time num false alarms0.20.30.50.70.5-0.7-0.6-0.5-0.40.3
Reaction time num false alarms AUC0.50.71.01.00.8-1.0-0.8-0.8-0.70.6
Reaction time trials correct on left1.82.63.91.71.8-1.7-1.3-1.5-2.01.2
Reaction time trials on left1.92.74.21.71.8-1.7-1.4-1.6-2.01.2
Reaction time mean0.10.20.30.60.4-0.4-0.6-0.4-0.10.5
Reaction time mean AUC0.10.20.30.60.4-0.4-0.5-0.4-0.10.4
Median of all reaction times0.10.20.40.60.4-0.3-0.5-0.3-0.00.4
Reaction time omissions0.50.71.01.00.8-0.8-0.7-0.7-1.00.7
Reaction time false alarm rate0.00.00.10.2-0.0-0.2-0.3-0.10.20.1
Reaction time premature initiation rate1.82.43.5-1.0-1.51.81.61.71.9-1.0
Reaction time premature initiations0.40.50.8-0.3-0.70.90.90.90.9-0.4
Std. dev. reaction times0.10.10.30.20.2-0.4-0.6-0.4-0.20.4
Reaction time trials completed1.92.74.21.71.8-1.7-1.4-1.6-2.01.2
Reaction time trials AUC1.42.03.11.41.5-1.5-1.2-1.4-1.81.1
Run reversals in cocaine runway, females1.41.42.51.21.6-1.1-0.9-1.1-1.11.1
Run reversals in cocaine runway, males0.10.10.2-0.4-0.2-0.40.1-0.3-0.40.0
Latency to leave start box in cocaine runway0.30.40.80.00.1-0.7-0.9-0.8-0.70.5
Latency to leave start box in cocaine runway, F0.40.40.70.70.4-0.7-0.7-0.7-0.80.3
Latency to leave start box in cocaine runway, M0.40.40.9-0.8-0.9-0.2-0.6-0.4-0.40.5
Std. dev. time between licks in bursts0.60.71.20.2-0.11.01.01.11.1-0.5
Total sessions with >9 infusions2.73.04.3-2.1-1.51.81.71.62.0-1.4
Short access day 1 total inactive lever presses4.34.86.1-2.0-1.52.42.52.52.4-2.0
Short access day 10 total inactive lever presses0.10.10.1-0.3-0.10.30.20.30.20.1
Short access day 1 total infusions1.11.21.8-1.3-0.31.31.11.11.2-1.0
Short access day 10 total infusions2.83.14.4-2.0-2.11.71.51.61.9-1.3
Short access total infusions3.54.05.7-2.4-1.62.21.91.92.2-1.5
Short access day 1 locomotion0.40.40.7-0.6-0.10.80.60.70.7-0.5
Short access day 10 total locomotion0.10.10.60.2-0.80.1-0.10.20.40.3
Short access total locomotion1.71.82.9-1.5-1.21.51.11.31.7-0.7
One hour access (0.3 mA shock)0.10.10.50.4-0.7-0.00.30.2-0.1-0.3
Compulsive drug intake0.30.31.31.10.4-0.6-0.0-0.4-0.4-0.4
One hour access (shock baseline)0.00.10.3-0.3-0.50.10.00.20.10.1
Social response proportion0.40.41.9-0.3-0.50.60.00.41.4-0.2
Social responses0.10.10.2-0.0-0.20.30.40.40.5-0.3
Social time0.10.20.80.90.10.10.40.40.0-0.4
Soleus weight0.20.51.0-0.1-0.30.71.00.80.3-0.9
Bone: stiffness3.86.07.5-2.7-2.72.52.32.42.5-1.9
Tibialis anterior weight0.10.20.40.5-0.30.50.60.6-0.0-0.1
Time to tail flick, vehicle, before self-admin0.20.20.6-0.4-0.50.40.60.50.2-0.7
Time to tail flick, vehicle, after self-admin0.91.02.41.21.5-1.0-0.7-0.7-0.90.7
Time to tail flick, test, before self-admin0.20.20.40.10.4-0.5-0.3-0.4-0.60.6
Time to tail flick, test, after self-admin0.30.31.01.00.8-0.4-0.3-0.3-0.50.1
Delta time to tail flick, vehicle, before/after SA0.30.31.10.51.0-0.3-0.4-0.20.10.7
Delta time to tail flick, test, before/after SA0.80.72.21.51.3-0.5-0.5-0.4-0.60.3
Tibia length0.72.13.8-2.0-1.51.41.41.31.1-1.3
Ambulatory time before self-admin0.10.10.20.50.2-0.1-0.0-0.00.10.3
Ambulatory time after self-admin1.31.42.6-0.4-0.61.41.61.51.4-0.9
Bone: tissue strength0.10.10.2-0.4-0.20.30.20.20.3-0.0
Total heroin consumption0.80.91.5-0.8-0.60.91.00.91.2-1.2
Bone: trabecular number0.40.61.00.40.7-0.8-0.8-0.8-1.00.9
Bone: trabecular spacing3.24.14.9-2.2-2.12.02.02.02.2-1.8
Bone: trabecular thickness0.80.91.51.00.8-0.9-1.1-0.9-1.20.9
Bone: trabecular tissue density0.10.10.50.7-0.20.40.30.50.2-0.2
Water consumed over 24 hours0.70.81.5-1.2-0.21.01.10.90.9-0.6
Number of responses in last shaping day3.83.95.1-0.9-2.32.12.12.31.8-2.1