Hub : Genes

Mrps9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Mrps9 0.36 0.14 2.7e-12 0.18 0.2 0.18 0.18 1.1e-09 8.9e-11 1.2e-09 7.7e-10
2 pVTA intron excision ratio chr9_52662585_52664212 0.06 0.04 1.7e-03 0.04 0.03 0.03 0.03 4.5e-04 3.2e-03 1.3e-03 1.2e-03
3 Liver mRNA stability Mrps9 0.15 0.08 1.9e-14 0.05 0.08 0.07 0.08 2.0e-06 2.1e-09 1.8e-08 4.3e-09
4 IC intron excision ratio chr9_52662585_52664212 0.1 0.07 5.3e-04 0.03 0.07 0.06 0.05 1.8e-02 5.6e-04 1.9e-03 3.3e-03
5 PL mRNA stability Mrps9 0.37 0.13 0.0e+00 0.21 0.24 0.23 0.23 1.6e-22 3.9e-26 7.9e-25 3.0e-25
6 Adipose mRNA stability Mrps9 0.44 0.12 0.0e+00 0.26 0.28 0.26 0.27 3.7e-28 9.5e-31 2.2e-29 7.0e-30
7 pVTA mRNA stability Mrps9 0.1 0.06 3.6e-06 0.04 0.05 0.03 0.04 2.5e-04 1.3e-04 2.1e-03 2.7e-04
8 NAcc mRNA stability Mrps9 0.27 0.11 0.0e+00 0.18 0.19 0.17 0.19 3.9e-26 4.2e-28 4.7e-25 4.7e-28
9 Brain mRNA stability Mrps9 0.33 0.12 0.0e+00 0.28 0.3 0.3 0.3 1.2e-26 2.4e-28 4.3e-28 4.4e-28
10 pVTA gene expression Mrps9 0.1 0.06 2.6e-05 0.07 0.05 0.05 0.06 2.1e-06 5.2e-05 5.9e-05 1.3e-05
11 IL mRNA stability Mrps9 0.44 0.18 7.6e-05 0.1 0.14 0.09 0.12 2.8e-03 2.8e-04 4.6e-03 9.4e-04
12 PL intron excision ratio chr9_52658406_52662416 0.06 0.04 7.3e-05 0.04 0.04 0.03 0.03 2.7e-05 8.8e-05 2.4e-04 1.9e-04
13 PL intron excision ratio chr9_52662585_52664212 0.15 0.07 5.7e-13 0.11 0.12 0.11 0.11 3.3e-12 8.6e-13 6.7e-12 3.7e-12
14 LHb mRNA stability Mrps9 0.26 0.14 3.6e-03 0.02 0.07 0.06 0.06 9.2e-02 1.0e-02 1.6e-02 1.7e-02
15 Liver intron excision ratio chr9_52658406_52662416 0.12 0.07 1.2e-07 0.05 0.04 0.04 0.04 5.5e-06 1.3e-05 5.0e-05 2.5e-05
16 Adipose gene expression Mrps9 0.14 0.07 5.6e-17 0.09 0.09 0.08 0.08 3.4e-10 3.6e-10 2.3e-09 3.1e-09
17 Liver gene expression Mrps9 0.18 0.1 0.0e+00 0.12 0.12 0.12 0.12 1.2e-13 1.8e-13 8.2e-13 1.1e-13
18 NAcc intron excision ratio chr9_52662585_52664212 0.09 0.05 4.6e-08 0.04 0.04 0.04 0.04 2.3e-06 2.0e-07 3.1e-06 2.6e-06
19 IC mRNA stability Mrps9 0.17 0.09 1.6e-04 0.05 0.06 0.06 0.06 3.4e-03 1.2e-03 1.1e-03 1.0e-03
20 NAcc gene expression Mrps9 0.05 0.03 3.3e-06 0.02 0.03 0.02 0.03 1.3e-03 6.4e-06 1.3e-04 4.5e-05
21 PL gene expression Mrps9 0.04 0.03 2.7e-04 0.01 0.03 0.02 0.02 1.6e-02 2.1e-04 5.6e-03 2.8e-03
22 Brain gene expression Mrps9 0.08 0.05 7.8e-05 0.05 0.05 0.05 0.05 1.3e-05 2.1e-05 2.2e-05 2.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density3.25.610.62.51.92.92.92.42.42.42.22.4-2.22.4-2.22.32.22.13.13.31.61.52.52.41.6
Area under the delay curve0.70.94.00.40.7-0.0-0.10.40.40.50.60.5-0.70.5-0.70.60.70.8-1.1-1.01.00.7-1.8-1.8-2.0
BMI with tail0.31.12.5-0.9-1.6-1.2-1.2-0.9-1.1-1.1-0.9-1.01.3-1.01.4-1.0-1.0-0.8-1.1-1.4-0.7-0.7-0.7-0.8-0.4
BMI without tail0.30.92.30.90.70.50.41.00.90.91.10.9-0.90.9-0.81.01.01.0-0.2-0.41.31.0-1.0-1.2-1.5
Body weight0.10.30.70.80.10.50.50.80.60.70.80.7-0.30.7-0.30.70.60.80.40.20.80.5-0.0-0.2-0.4
Weight adjusted by age2.13.36.1-1.8-2.3-1.6-1.5-1.8-1.9-1.9-1.9-1.92.5-1.92.2-2.0-2.0-2.0-0.9-1.0-2.0-2.20.50.61.5
Bone surface0.40.71.60.80.61.01.00.90.80.80.70.9-0.91.0-0.80.90.80.71.01.30.50.60.80.80.9
Bone volume1.73.16.01.81.42.12.11.81.81.81.61.8-1.71.8-1.71.71.61.52.22.41.21.21.71.71.3
Breakpoint value in progressive ratio session1.51.73.41.61.51.31.21.61.41.41.71.3-1.51.1-1.21.31.31.50.80.91.71.80.2-0.1-0.7
Number of licking bursts0.20.31.00.41.00.40.40.50.50.60.50.6-0.70.7-0.70.70.70.6-0.00.10.60.6-0.6-0.5-0.5
Context. condit. distance diff. score0.80.92.60.90.41.11.20.90.80.80.70.9-0.70.9-0.70.80.70.61.41.60.3-0.11.41.41.2
Locomotion velocity, session 10.00.00.10.10.30.10.10.20.10.10.10.2-0.20.2-0.20.20.20.10.00.00.1-0.4-0.1-0.1-0.2
Locomotion distance, session 11.51.93.8-1.3-1.6-1.4-1.4-1.4-1.6-1.5-1.4-1.51.6-1.51.6-1.6-1.6-1.5-1.0-1.0-1.4-1.9-0.1-0.10.4
Locomotion velocity, session 23.33.95.4-2.2-1.8-2.3-2.3-2.1-2.2-2.2-2.1-2.12.1-2.12.1-2.1-2.1-1.9-2.2-2.0-1.9-1.7-1.3-1.1-0.0
Locomotion distance, session 22.02.84.1-1.8-1.8-2.0-2.0-1.7-1.8-1.8-1.6-1.81.7-1.71.6-1.7-1.7-1.6-2.0-2.0-1.4-1.3-1.4-1.3-0.5
Locomotion velocity, session 30.10.10.60.0-0.10.10.1-0.0-0.1-0.1-0.1-0.10.1-0.20.2-0.2-0.2-0.10.40.4-0.3-0.30.60.60.7
Locomotion distance, session 30.10.10.30.30.60.30.40.30.30.30.30.2-0.20.2-0.20.20.20.30.40.50.20.20.50.40.3
Stereotopy head waving bouts, day 30.40.50.80.80.30.80.70.70.80.80.80.7-0.80.6-0.80.70.80.60.60.60.80.90.10.1-0.2
Stereotopy head waving duration, day 30.30.40.60.70.30.60.60.60.70.70.70.7-0.80.6-0.80.70.70.60.30.30.80.7-0.2-0.2-0.4
Locomotion velocity, session 72.93.24.8-2.0-1.9-1.7-1.7-1.9-2.0-2.0-2.1-1.92.0-1.82.0-2.0-2.0-2.0-1.0-0.9-2.1-2.20.10.31.3
Locomotion distance, session 70.81.01.4-1.1-1.0-1.2-1.2-1.0-1.2-1.1-1.1-1.01.1-0.91.1-1.0-1.0-1.1-1.0-0.9-1.1-1.2-0.5-0.40.2
Stereotopy head waving bouts, day 70.10.10.30.40.10.50.50.40.40.40.50.3-0.30.1-0.30.30.20.30.50.50.30.10.40.40.4
Stereotopy head waving duration, day 70.20.21.40.0-0.20.20.2-0.0-0.1-0.1-0.1-0.20.2-0.30.2-0.2-0.3-0.20.60.7-0.3-0.61.01.01.2
Locomotion velocity, session 81.01.23.3-0.9-0.9-0.5-0.5-0.9-1.0-1.0-1.2-1.01.1-0.81.1-1.0-1.1-1.10.30.4-1.5-1.81.31.41.8
Locomotion distance, session 80.91.43.3-1.1-1.4-0.9-0.8-1.0-1.2-1.2-1.3-1.11.3-1.01.3-1.2-1.2-1.4-0.1-0.0-1.5-1.80.80.91.5
Degree of sensitization distance0.91.02.2-1.0-0.9-1.2-1.2-0.9-1.0-0.9-0.9-0.80.8-0.70.8-0.7-0.7-0.8-1.5-1.4-0.6-0.7-1.3-1.3-0.7
Degree of sensitization stereotypy0.10.10.40.1-0.10.20.20.10.00.00.1-0.10.1-0.20.1-0.1-0.1-0.10.50.5-0.1-0.30.60.60.7
Conditioned locomotion1.01.11.81.20.91.11.11.21.21.21.31.1-1.21.0-1.31.11.11.10.80.81.31.20.20.1-0.4
Cocaine response after cond. corrected0.40.52.30.20.7-0.1-0.20.30.30.30.40.4-0.60.4-0.50.50.50.6-0.9-0.90.70.7-1.4-1.5-1.5
Cocaine response after cond. not corrected0.20.21.1-0.00.4-0.3-0.30.10.00.00.10.1-0.20.1-0.10.20.20.3-0.8-0.70.30.3-1.0-1.0-0.9
Cocaine response before conditioning0.81.02.2-0.7-0.9-0.6-0.6-0.8-0.9-0.9-0.9-1.11.3-1.21.3-1.1-1.2-1.10.20.2-1.1-1.21.01.01.5
Saline control response0.81.12.0-1.1-1.3-0.9-0.8-1.1-1.1-1.1-1.2-1.11.0-1.01.0-1.1-1.1-1.3-0.3-0.3-1.3-1.40.40.51.1
Bone: connectivity density0.91.42.31.30.91.41.41.31.31.31.21.2-1.31.3-1.21.31.21.11.31.51.01.00.90.80.6
Bone: cortical apparent density5.06.89.1-2.8-3.0-2.7-2.7-2.8-2.9-2.9-2.9-2.93.0-2.93.0-3.0-3.0-3.0-1.8-1.7-2.9-2.8-0.10.01.3
Bone: cortical area0.10.10.8-0.1-0.6-0.00.0-0.1-0.2-0.2-0.1-0.30.2-0.20.2-0.2-0.3-0.30.20.5-0.3-0.30.50.50.9
Bone: cortical porosity0.80.91.90.91.11.11.10.91.01.00.80.9-0.91.0-0.90.90.90.91.11.40.60.70.80.80.7
Bone: cortical porosity1.01.12.90.90.91.31.31.01.01.00.81.0-0.91.1-0.81.00.90.91.51.70.50.31.31.31.1
Bone: cortical thickness0.10.21.3-0.2-0.50.00.0-0.2-0.2-0.2-0.2-0.30.1-0.30.1-0.2-0.3-0.40.30.6-0.4-0.60.70.71.1
Bone: cortical thickness0.10.10.4-0.1-0.3-0.0-0.0-0.1-0.1-0.1-0.2-0.10.1-0.10.1-0.1-0.1-0.10.10.3-0.3-0.60.30.30.7
Bone: cortical tissue density4.86.68.9-2.7-2.9-2.6-2.6-2.8-2.9-2.9-2.9-2.92.9-2.83.0-2.9-2.9-3.0-1.6-1.6-2.9-2.80.00.21.4
Condit. Reinf. active minus inactive responses0.40.41.90.40.60.10.10.40.40.50.70.4-0.60.2-0.50.40.50.5-0.5-0.60.90.2-1.1-1.1-1.4
Condit. Reinf. active-inactive response ratio0.40.51.40.60.90.40.30.60.60.70.80.6-0.80.5-0.70.60.70.7-0.1-0.21.00.1-0.8-0.8-1.2
Condit. Reinf. active responses0.10.10.60.10.1-0.1-0.20.10.10.10.30.0-0.2-0.1-0.10.10.10.1-0.4-0.50.4-0.1-0.7-0.8-0.8
Condit. Reinf. inactive responses0.50.60.8-0.8-0.8-0.9-0.9-0.8-0.8-0.8-0.7-0.90.8-0.90.9-0.8-0.8-0.8-0.9-0.7-0.7-0.4-0.5-0.50.0
Incentive salience index mean0.10.10.20.30.30.20.20.30.30.40.40.3-0.40.3-0.40.30.40.30.0-0.00.5-0.2-0.3-0.3-0.4
Condit. Reinf. lever presses0.20.31.30.2-0.30.40.50.20.10.10.10.10.00.20.00.10.1-0.00.80.9-0.2-0.61.01.01.1
Condit. Reinf. active minus inactive responses0.60.81.90.91.40.70.70.90.90.91.00.9-1.10.7-1.10.91.01.00.10.21.20.8-0.5-0.6-1.0
Condit. Reinf. active-inactive response ratio1.82.13.31.61.81.61.51.51.71.61.71.6-1.71.5-1.71.51.61.61.01.01.71.30.20.1-0.8
Condit. Reinf. active responses0.20.31.20.20.6-0.1-0.10.20.20.20.40.2-0.50.1-0.40.30.30.4-0.6-0.40.60.4-1.0-1.1-0.9
Condit. Reinf. inactive responses1.41.82.4-1.5-1.4-1.6-1.6-1.4-1.5-1.5-1.5-1.41.4-1.41.4-1.4-1.4-1.3-1.3-1.1-1.4-1.2-0.7-0.70.4
Condit. Reinf. lever presses0.30.41.00.61.00.50.50.60.60.60.70.6-0.70.5-0.70.60.60.80.20.40.70.7-0.2-0.2-0.3
Condit. Reinf. lever reinforcers received0.20.31.6-0.00.4-0.3-0.30.00.10.10.20.1-0.3-0.0-0.30.10.20.3-0.9-0.60.50.3-1.2-1.3-1.0
Conditioned reinforcement - actives0.10.10.70.30.20.0-0.00.30.20.20.40.2-0.10.20.40.20.20.4-0.3-0.20.50.4-0.5-0.7-0.8
Conditioned reinforcement - inactives0.30.41.4-0.2-0.6-0.4-0.3-0.3-0.6-0.6-0.3-0.60.9-0.81.2-0.8-0.8-0.40.10.2-0.5-0.60.80.60.7
Conditioned locomotion0.70.92.1-0.8-1.2-0.9-0.8-0.9-1.0-1.0-0.8-1.01.2-1.01.5-1.1-1.1-0.9-0.4-0.3-1.0-1.30.20.20.6
Patch foraging indifference point 0 sec0.61.12.0-1.0-1.4-0.9-0.9-1.0-1.1-1.1-1.2-1.11.2-1.11.1-1.2-1.2-1.2-0.2-0.3-1.3-1.10.50.61.2
Patch foraging indifference point AUC0.20.31.0-0.3-0.1-0.5-0.6-0.4-0.3-0.3-0.1-0.40.5-0.50.5-0.4-0.3-0.2-0.6-1.00.00.6-0.8-0.8-0.7
Delay disc. indifference point, 0s delay1.61.82.9-1.5-1.2-1.3-1.3-1.4-1.5-1.5-1.6-1.41.6-1.31.7-1.4-1.5-1.4-0.9-0.8-1.6-1.60.10.20.8
Delay disc. indifference point, 16s delay2.02.23.61.51.91.21.11.51.51.61.61.7-1.71.7-1.81.71.81.70.10.21.81.2-0.9-1.0-1.7
Delay disc. indifference point, 2s delay0.30.41.90.30.4-0.1-0.20.30.20.20.40.2-0.40.1-0.20.30.30.6-0.8-0.70.70.7-1.1-1.2-1.4
Delay disc. indifference point, 24s delay0.10.10.30.20.50.10.10.20.20.30.20.4-0.20.4-0.40.40.40.30.0-0.10.3-0.0-0.5-0.4-0.5
Delay disc. indifference point, 4s delay0.30.30.7-0.6-0.7-0.7-0.7-0.5-0.6-0.5-0.5-0.50.6-0.50.6-0.5-0.5-0.3-0.8-0.8-0.4-0.5-0.6-0.6-0.3
Delay disc. indifference point, 8s delay0.60.72.90.40.80.10.00.50.50.50.60.6-0.80.5-0.90.60.70.6-0.7-0.70.90.8-1.4-1.4-1.7
Indifference point function ln k0.91.62.9-1.6-1.1-1.5-1.5-1.4-1.4-1.4-1.6-1.21.0-1.01.0-1.2-1.2-1.3-1.7-1.3-1.3-1.2-1.1-0.9-0.1
Indifference point function log k0.91.62.9-1.6-1.1-1.5-1.5-1.4-1.4-1.4-1.6-1.21.0-1.01.0-1.2-1.2-1.3-1.7-1.3-1.3-1.2-1.1-0.9-0.1
Patch foraging total patch changes 0 sec0.40.71.5-0.9-1.2-0.8-0.8-0.9-0.9-0.9-0.9-0.91.0-0.90.9-1.0-1.0-0.9-0.3-0.4-1.0-0.80.20.20.8
Patch foraging total patch changes 12 sec0.30.42.60.1-0.30.20.20.0-0.2-0.2-0.1-0.30.7-0.40.7-0.4-0.5-0.20.90.6-0.5-0.31.41.31.6
Patch foraging total patch changes 18 sec0.30.41.2-0.6-0.6-0.8-0.8-0.6-0.6-0.6-0.4-0.60.6-0.80.5-0.6-0.6-0.6-0.7-1.1-0.20.3-0.8-0.8-0.4
Patch foraging total patch changes 24 sec0.30.51.3-0.4-1.1-0.4-0.4-0.5-0.7-0.7-0.6-0.70.9-0.80.9-0.8-0.8-0.80.3-0.1-0.8-0.50.70.71.0
Patch foraging total patch changes 6 sec0.10.20.6-0.4-0.8-0.3-0.3-0.5-0.4-0.4-0.4-0.50.6-0.70.5-0.6-0.6-0.50.1-0.1-0.40.10.40.30.6
Patch foraging time to switch 0 sec0.20.51.50.70.60.80.80.60.50.50.40.5-0.50.5-0.60.40.40.21.11.00.20.11.21.10.8
Patch foraging water rate 0 sec0.20.41.80.00.1-0.2-0.30.20.20.20.40.2-0.00.1-0.20.20.30.7-0.9-0.80.60.7-1.3-1.3-1.2
Patch foraging water rate 12 sec0.10.31.3-0.5-0.2-0.5-0.5-0.5-0.2-0.2-0.3-0.20.2-0.2-0.0-0.2-0.1-0.1-1.0-0.80.00.3-1.2-1.0-0.9
Patch foraging water rate 18 sec0.00.00.2-0.2-0.1-0.2-0.2-0.1-0.1-0.2-0.1-0.2-0.1-0.3-0.1-0.2-0.1-0.0-0.50.10.00.1-0.2-0.3-0.0
Patch foraging water rate 24 sec0.10.20.5-0.5-0.6-0.5-0.5-0.5-0.4-0.4-0.5-0.30.0-0.3-0.1-0.3-0.3-0.2-0.7-0.4-0.3-0.6-0.6-0.5-0.4
Patch foraging water rate 6 sec0.40.62.5-0.8-0.2-0.8-0.8-0.7-0.4-0.4-0.4-0.40.5-0.40.4-0.3-0.2-0.2-1.2-1.1-0.10.1-1.6-1.4-1.0
Seeking ratio, delayed vs. immediate footshock0.70.82.61.20.01.11.21.00.90.91.00.9-0.10.8-0.10.80.70.81.61.10.60.21.31.10.6
Distance traveled before self-admin1.01.32.91.20.91.41.41.31.21.21.01.2-0.81.3-0.91.21.11.01.71.40.70.61.21.20.6
Distance traveled after self-admin2.32.88.61.60.81.92.01.51.31.31.21.3-0.81.4-0.91.11.01.02.92.70.50.22.92.72.1
Extensor digitorum longus weight6.726.535.8-5.7-5.7-6.0-6.0-5.7-5.6-5.6-5.4-5.65.3-5.55.3-5.4-5.3-5.4-5.5-5.6-4.6-4.0-3.3-2.9-0.7
Bone: elastic displacement1.72.03.61.41.91.31.21.41.51.51.51.5-1.71.5-1.71.51.61.60.60.81.61.9-0.2-0.3-0.9
Bone: elastic work1.31.62.31.41.31.41.41.41.41.41.31.4-1.51.4-1.51.41.41.31.21.41.21.10.60.50.0
Bone: endosteal estimation0.10.20.30.50.20.40.40.50.40.50.50.5-0.30.6-0.30.50.50.60.20.30.50.5-0.1-0.1-0.2
Bone: endosteal perimeter0.10.10.30.40.40.30.30.40.40.40.50.4-0.20.3-0.20.40.40.40.20.20.50.6-0.1-0.2-0.2
Epididymis fat weight0.10.30.8-0.4-0.4-0.6-0.7-0.4-0.4-0.4-0.2-0.50.3-0.60.5-0.4-0.4-0.3-0.9-0.7-0.1-0.3-0.8-0.8-0.5
Delta time in closed arm before/after self-admin0.20.21.30.40.60.20.10.30.30.30.40.2-0.60.0-0.60.30.30.4-0.1-0.10.61.1-0.3-0.4-0.5
Delta time in open arm before/after self-admin0.10.10.50.00.30.40.40.20.30.30.00.5-0.20.7-0.70.50.50.30.40.4-0.0-0.40.10.20.2
Diff in mean of infusions in LGA sessions0.91.01.61.21.21.01.01.21.11.11.21.1-1.31.0-1.21.11.11.10.70.91.11.20.30.1-0.4
Delay discount exponential model param0.80.94.1-0.4-0.7-0.00.1-0.5-0.5-0.5-0.7-0.60.7-0.60.8-0.7-0.8-0.91.01.0-1.1-0.81.71.82.0
Extinction: sum of active levers before priming4.85.37.72.82.32.62.62.72.62.62.72.5-2.42.4-2.22.42.42.52.32.32.42.11.20.9-0.2
Active lever presses in extinction session 60.40.42.00.60.50.10.10.60.40.50.80.4-0.40.2-0.30.40.50.8-0.5-0.51.00.8-0.9-1.1-1.4
Bone: final force0.20.42.0-0.2-0.80.00.1-0.2-0.3-0.3-0.4-0.30.4-0.20.4-0.3-0.4-0.40.50.7-0.7-0.91.11.11.4
Bone: final moment0.20.31.6-0.3-0.8-0.00.0-0.2-0.3-0.3-0.3-0.30.3-0.20.4-0.3-0.4-0.30.40.6-0.6-0.80.80.91.3
Food consumed during 24 hour testing period0.10.20.5-0.3-0.3-0.6-0.6-0.2-0.4-0.4-0.2-0.40.4-0.40.4-0.3-0.3-0.1-0.7-0.7-0.1-0.2-0.6-0.7-0.5
Glucose0.71.11.81.11.00.90.91.11.11.21.11.2-1.21.1-1.21.21.21.20.30.31.31.4-0.5-0.5-1.1
Heart weight0.10.10.5-0.2-0.0-0.5-0.5-0.2-0.3-0.3-0.3-0.20.2-0.20.2-0.2-0.2-0.1-0.6-0.6-0.10.3-0.6-0.7-0.5
Delay discount hyperbolic model param0.70.84.0-0.3-0.50.10.2-0.4-0.4-0.4-0.5-0.50.6-0.40.7-0.5-0.6-0.81.11.1-1.0-0.71.71.82.0
Intermittent access intake day 1-15 change0.10.21.00.40.00.50.50.40.20.30.20.3-0.20.40.00.20.20.10.81.0-0.0-0.30.90.80.7
Intermittent access intake escalation0.10.21.00.2-0.10.40.40.20.20.20.10.2-0.10.30.10.10.1-0.10.81.0-0.2-0.30.90.90.9
Intermittent access intake escalation 20.40.51.00.90.50.80.80.90.70.70.80.7-0.50.7-0.50.60.60.61.01.00.60.30.80.60.3
Intermitt. access day 1 inactive lever presses0.20.71.81.00.81.01.01.00.80.80.80.8-0.50.9-0.70.80.70.81.21.30.50.31.10.90.4
Intermitt. access day 15 inactive lever presses0.30.61.1-0.8-0.8-0.5-0.5-0.8-0.8-0.8-0.9-0.70.8-0.70.6-0.8-0.8-0.90.00.1-1.0-0.80.60.71.0
Intermitt. access escalation Index0.20.31.0-0.7-0.6-0.5-0.5-0.7-0.5-0.6-0.6-0.60.7-0.60.3-0.5-0.6-0.6-0.3-0.6-0.6-1.0-0.10.10.5
Intermittent access day 1 total infusions2.03.26.62.12.01.31.22.01.81.82.31.8-1.81.5-1.31.81.92.20.20.12.62.3-1.1-1.5-2.5
Intermittent access day 15 total infusions0.50.71.31.10.80.80.81.00.90.91.10.9-0.80.8-0.30.80.91.00.50.61.10.8-0.0-0.2-0.8
Intermittent access terminal intake (last 3 days)0.70.91.91.31.00.80.71.31.01.01.41.0-0.80.8-0.30.91.01.20.40.41.41.3-0.2-0.5-1.1
Intermittent access total infusions1.11.32.51.41.20.90.81.31.21.21.51.2-1.11.1-0.61.11.21.40.20.31.61.5-0.5-0.8-1.5
Intermittent access day 1 locomotion0.20.21.30.50.30.0-0.00.50.30.30.60.3-0.10.20.10.30.30.6-0.3-0.40.70.4-0.6-0.8-1.2
Intermittent access day 15 total locomotion0.30.61.4-0.7-0.9-0.9-0.9-0.7-0.9-0.9-0.7-0.91.0-0.91.2-0.9-0.9-0.7-0.7-0.5-0.7-0.8-0.2-0.30.0
Intermittent access total locomotion0.20.20.5-0.2-0.3-0.6-0.6-0.2-0.4-0.4-0.2-0.40.4-0.50.7-0.4-0.4-0.1-0.7-0.5-0.1-0.3-0.4-0.6-0.5
Intermittent access standard deviation0.61.32.11.41.11.31.31.41.21.31.31.3-1.31.3-0.81.21.21.21.31.41.10.70.70.5-0.1
Left kidney weight0.10.31.40.50.10.50.60.50.30.30.30.30.10.40.40.30.20.30.90.8-0.00.31.11.01.2
Right kidney weight0.31.44.6-0.6-1.3-0.5-0.4-0.6-1.0-1.0-1.0-0.91.5-0.81.9-1.0-1.1-1.00.60.4-1.4-1.61.61.52.1
Cocaine induced anxiety1.01.42.4-1.5-1.3-1.1-1.0-1.4-1.3-1.3-1.5-1.31.4-1.21.1-1.3-1.3-1.3-0.6-0.7-1.6-1.20.20.41.1
Post-drug Anxiety1.21.31.8-1.3-1.3-1.0-1.0-1.3-1.2-1.2-1.3-1.31.3-1.31.2-1.3-1.3-1.1-0.6-0.7-1.3-1.30.10.30.9
Baseline Anxiety0.30.30.90.60.60.20.20.50.50.50.80.4-0.50.2-0.40.40.50.8-0.2-0.20.90.5-0.7-0.8-1.0
Tail length1.45.37.82.62.62.32.22.62.62.62.82.6-2.72.4-2.62.62.62.61.31.42.82.4-0.2-0.4-1.3
Length with tail0.83.54.82.21.82.12.02.22.12.12.22.1-1.92.0-2.02.12.02.01.81.71.91.60.80.5-0.0
Length without tail0.00.10.50.1-0.50.10.10.1-0.0-0.00.0-0.10.3-0.10.3-0.1-0.10.00.40.4-0.20.10.60.50.7
Times rat made contact with spout2.22.53.81.61.71.31.31.71.71.71.81.8-1.81.8-1.81.81.91.90.40.51.91.9-0.7-0.9-1.3
Lifetime Intake0.70.81.81.10.90.60.61.10.90.91.21.0-0.80.9-0.30.91.01.20.10.21.31.1-0.5-0.8-1.3
Liver weight, left1.01.62.91.21.31.00.91.41.31.31.41.4-1.31.5-1.31.51.51.60.20.41.51.7-0.8-0.9-1.1
Liver weight, right1.32.33.81.61.01.61.51.61.81.81.81.7-1.71.6-1.91.71.81.80.91.01.81.9-0.2-0.2-0.6
Locomotor activity0.30.40.80.80.70.70.70.70.70.70.90.6-0.70.5-0.60.60.70.60.40.50.80.90.10.0-0.3
Locomotor testing distance0.71.22.21.21.21.31.41.11.21.21.11.1-1.11.0-1.01.01.00.91.41.50.90.90.90.90.5
Locomotor testing rearing0.61.23.50.91.11.31.30.90.90.90.70.9-0.81.0-0.70.80.80.61.71.90.3-0.01.51.61.4
Locomotion in novel chamber3.44.36.9-2.1-2.2-2.5-2.5-2.1-2.2-2.2-1.8-2.32.2-2.42.2-2.2-2.1-1.8-2.5-2.6-1.5-1.0-1.8-1.8-0.8
Locomotion in novel chamber post-restriction0.91.42.9-1.2-1.0-1.4-1.3-1.2-1.2-1.2-1.0-1.31.6-1.41.7-1.3-1.2-0.9-1.5-1.4-0.9-0.6-0.9-0.8-0.1
Fecal boli incidents, locomotor time 10.40.51.9-0.8-0.4-0.9-0.9-0.6-0.6-0.6-0.7-0.40.1-0.30.2-0.3-0.3-0.4-1.2-1.3-0.3-0.3-1.4-1.2-1.0
Change in fecal boli incidents, locomotor task0.20.20.60.40.60.40.40.40.30.30.20.3-0.10.50.00.30.20.30.60.8-0.00.10.70.60.5
Time >=10cm from walls, locomotor time 13.43.65.9-2.4-1.9-2.2-2.2-2.3-2.1-2.1-2.3-1.91.8-1.71.5-1.8-1.8-1.9-2.2-2.1-1.9-1.3-1.6-1.3-0.5
Bouts of movement, locomotor time 12.83.212.0-1.6-0.7-2.0-2.1-1.5-1.2-1.2-1.0-1.20.5-1.30.4-1.0-0.9-0.8-3.0-3.0-0.10.1-3.5-3.3-2.6
Total resting periods, locomotor time 13.13.510.9-1.8-1.1-2.1-2.2-1.7-1.4-1.4-1.3-1.40.8-1.60.7-1.3-1.1-1.0-3.0-3.0-0.5-0.1-3.3-3.1-2.3
Rest time, locomotor task time 11.31.64.01.11.20.70.61.11.21.21.31.2-1.41.2-1.31.31.41.5-0.3-0.41.71.6-1.5-1.6-2.0
Distance moved, locomotor task time 10.10.20.6-0.3-0.3-0.5-0.5-0.4-0.5-0.6-0.4-0.70.6-0.80.5-0.6-0.6-0.5-0.2-0.4-0.4-0.40.0-0.00.1
Vertical activity count, locomotor time 10.20.41.9-0.1-0.30.20.3-0.2-0.2-0.2-0.3-0.20.3-0.20.1-0.3-0.3-0.50.80.9-0.6-1.01.31.41.3
Time >=10cm from walls, locomotor time 20.00.00.20.00.40.10.10.10.10.10.00.2-0.30.4-0.40.20.20.20.00.00.10.4-0.2-0.1-0.3
Bouts of movement, locomotor time 20.81.32.9-1.1-0.8-1.3-1.4-1.1-1.0-1.0-0.7-1.20.9-1.31.1-1.1-1.0-0.9-1.6-1.7-0.5-0.7-1.3-1.3-0.8
Total resting periods, locomotor time 20.61.02.2-0.9-0.6-1.2-1.2-1.0-0.9-0.9-0.6-1.10.9-1.31.2-1.1-1.0-0.8-1.3-1.5-0.4-0.6-1.1-1.1-0.6
Rest time, locomotor task time 20.20.20.40.30.70.50.50.30.60.50.40.5-0.50.5-0.50.50.50.40.40.30.50.6-0.2-0.1-0.3
Distance moved, locomotor task time 20.60.81.5-0.9-0.8-1.1-1.1-0.9-0.9-0.9-0.8-0.90.7-1.00.6-0.9-0.8-0.8-1.2-1.1-0.5-0.5-1.0-0.9-0.5
Vertical activity count, locomotor time 20.50.72.1-0.9-1.3-0.7-0.7-0.9-0.8-0.8-0.9-0.80.8-0.70.6-0.8-0.8-0.9-0.5-0.4-1.0-1.50.10.20.5
Light reinforcement 11.64.06.0-2.0-2.4-2.3-2.3-2.0-2.3-2.3-2.0-2.22.3-2.32.5-2.2-2.2-2.1-1.8-1.9-1.8-1.5-0.8-0.80.1
Light reinforcement 20.30.51.7-0.4-1.3-0.7-0.8-0.4-0.6-0.7-0.4-0.70.9-0.81.0-0.7-0.7-0.5-0.7-0.8-0.20.1-0.4-0.6-0.3
Bone: marrow area0.10.10.30.40.20.30.30.40.40.40.40.4-0.20.5-0.20.40.40.50.10.20.40.4-0.1-0.1-0.2
Bone: maximum diameter0.20.30.70.60.20.70.70.60.60.60.60.5-0.50.5-0.50.50.50.50.70.90.40.60.60.50.5
Bone: maximum force0.20.31.5-0.3-0.9-0.1-0.0-0.2-0.3-0.3-0.4-0.30.4-0.20.4-0.3-0.4-0.40.40.5-0.7-0.80.80.91.2
Bone: maximum moment0.10.21.1-0.4-0.9-0.2-0.1-0.3-0.4-0.4-0.4-0.30.3-0.20.4-0.3-0.4-0.40.20.3-0.6-0.70.50.61.0
Mean time between licks in bursts0.92.23.1-1.7-1.7-1.7-1.7-1.6-1.7-1.7-1.6-1.71.8-1.71.7-1.7-1.7-1.5-1.4-1.4-1.5-0.7-0.5-0.50.2
Mean num. licks in bursts0.00.00.20.2-0.4-0.0-0.00.10.10.10.20.0-0.0-0.1-0.00.00.00.2-0.1-0.30.30.3-0.2-0.3-0.4
Cd content in liver3.74.17.32.32.72.22.22.32.32.32.32.3-2.12.2-2.12.32.22.31.71.52.11.70.60.4-0.5
Co content in liver1.21.42.71.41.71.21.21.41.41.41.41.3-1.31.3-1.31.41.31.40.80.71.30.80.1-0.0-0.6
Cu content in liver0.20.30.50.60.50.60.60.60.60.60.70.5-0.40.5-0.40.50.50.60.60.50.60.10.20.1-0.0
Fe content in liver2.63.25.51.91.52.22.21.91.91.91.71.9-1.71.9-1.71.81.81.72.32.21.41.41.51.50.8
K content in liver1.61.52.9-1.4-1.7-1.3-1.4-1.4-1.3-1.4-1.4-1.41.2-1.41.2-1.4-1.3-1.4-1.1-1.0-1.2-0.6-0.6-0.40.2
Mg content in liver0.40.40.8-0.7-0.9-0.6-0.6-0.7-0.7-0.7-0.8-0.70.6-0.60.6-0.6-0.6-0.7-0.4-0.2-0.8-0.5-0.00.10.4
Mn content in liver0.80.91.7-1.1-1.3-0.9-0.8-1.2-1.0-1.0-1.2-1.01.0-1.01.0-1.1-1.1-1.2-0.4-0.5-1.1-1.20.20.30.3
Na content in liver0.60.72.60.2-0.00.70.80.40.30.3-0.10.5-0.20.9-0.20.50.40.21.31.4-0.5-0.51.51.61.6
Rb content in liver3.64.16.2-2.1-2.5-2.3-2.3-2.2-2.1-2.1-1.9-2.22.0-2.42.0-2.2-2.1-2.1-2.1-2.4-1.5-1.9-1.5-1.4-0.7
Se content in liver0.10.10.3-0.1-0.4-0.3-0.3-0.1-0.2-0.2-0.0-0.20.2-0.20.2-0.1-0.1-0.1-0.3-0.40.10.1-0.5-0.5-0.5
Sr content in liver0.20.10.60.10.50.0-0.00.20.20.20.10.3-0.40.4-0.40.30.30.4-0.3-0.20.30.7-0.6-0.6-0.6
Zn content in liver0.10.10.10.30.20.30.20.30.20.30.40.2-0.10.1-0.10.20.20.30.20.30.30.30.10.00.2
Bone: minimum diameter0.20.41.4-0.7-1.2-0.6-0.6-0.6-0.7-0.7-0.6-0.70.8-0.60.8-0.6-0.7-0.6-0.4-0.3-0.7-0.60.00.00.5
Time in familiar zone, hab. session 11.91.93.21.51.51.21.21.51.51.51.71.5-1.51.4-1.51.51.61.50.40.41.81.6-0.6-0.7-1.2
Time in novel zone, hab. session 10.20.20.30.50.60.50.50.40.40.40.40.4-0.50.4-0.50.40.40.20.50.40.30.50.40.4-0.0
Total zone transitions, hab. session 11.31.93.8-1.2-1.4-0.9-0.8-1.2-1.3-1.3-1.4-1.31.6-1.31.6-1.4-1.5-1.70.20.1-1.7-1.81.31.41.9
Total locomotion distance, hab. session 11.11.52.2-1.3-1.5-1.3-1.3-1.3-1.4-1.4-1.2-1.41.4-1.41.5-1.4-1.4-1.4-1.0-1.0-1.2-1.2-0.3-0.30.4
Locomotion velocity, hab. session 11.31.93.0-1.4-1.7-1.4-1.4-1.4-1.5-1.5-1.5-1.51.6-1.51.7-1.5-1.6-1.6-0.8-0.8-1.5-1.50.10.10.9
Time in familiar zone, hab. session 20.40.40.80.70.70.70.70.70.70.70.80.7-0.60.6-0.60.70.70.70.50.50.70.90.10.1-0.1
Time in novel zone, hab. session 20.00.00.10.00.10.00.10.00.00.0-0.00.1-0.20.1-0.20.00.0-0.00.10.1-0.0-0.20.10.1-0.1
Total zone transitions, hab. session 20.10.20.4-0.3-0.6-0.5-0.5-0.3-0.4-0.4-0.3-0.40.6-0.40.6-0.4-0.4-0.4-0.4-0.6-0.2-0.5-0.2-0.3-0.2
Total locomotion distance, hab. session 20.81.12.8-0.8-0.9-1.2-1.3-0.8-0.9-0.9-0.6-0.90.8-1.00.8-0.8-0.8-0.6-1.6-1.7-0.3-0.4-1.5-1.6-1.2
Locomotion velocity, hab. session 20.91.12.4-0.9-1.1-1.3-1.3-0.9-1.1-1.0-0.8-1.01.0-1.11.1-1.0-0.9-0.8-1.4-1.6-0.5-0.7-1.2-1.3-0.8
Novel to familiar place preference ratio1.51.62.51.11.40.80.81.21.31.31.41.3-1.51.3-1.51.41.51.5-0.10.01.61.5-1.2-1.2-1.5
Novelty place preference1.51.62.51.11.50.90.81.21.31.31.41.3-1.61.3-1.61.41.51.5-0.10.11.61.5-1.1-1.2-1.4
Time in novel zone, NPP test2.12.23.41.41.81.11.11.51.61.61.61.6-1.91.6-1.81.71.71.80.10.31.81.7-1.1-1.1-1.5
Total zone transitions, NPP test0.71.11.8-1.0-0.9-1.1-1.1-1.0-1.2-1.1-1.0-1.11.2-1.11.3-1.1-1.2-1.1-0.8-0.9-1.0-1.3-0.2-0.20.2
Total locomotion distance, NPP test0.81.11.8-1.1-0.8-1.3-1.3-1.0-1.1-1.1-0.9-1.11.0-1.21.0-1.1-1.0-0.9-1.3-1.3-0.7-0.7-1.0-1.0-0.4
Locomotion velocity, NPP test1.62.23.0-1.6-1.4-1.7-1.7-1.6-1.6-1.6-1.5-1.61.6-1.71.6-1.6-1.6-1.5-1.6-1.5-1.3-1.3-0.9-0.80.0
Intraocular pressure1.11.63.1-1.3-1.1-1.6-1.6-1.3-1.3-1.3-1.1-1.31.4-1.41.3-1.3-1.2-1.1-1.8-1.6-0.9-0.8-1.2-1.2-0.7
Delta distance traveled before/after self-admin0.20.21.0-0.0-0.30.10.1-0.1-0.2-0.2-0.3-0.30.3-0.30.2-0.3-0.4-0.30.60.7-0.4-0.41.01.01.0
Delta ambulatory time before/after self-admin0.20.20.8-0.1-0.4-0.1-0.1-0.2-0.4-0.4-0.3-0.40.4-0.50.4-0.5-0.5-0.40.40.4-0.5-0.50.90.80.9
Parametrial fat weight0.00.00.20.2-0.30.10.10.20.20.20.20.20.10.10.00.20.20.40.1-0.10.20.5-0.1-0.1-0.2
Pavlov. Cond. lever latency0.40.52.0-0.50.1-0.7-0.8-0.5-0.4-0.4-0.3-0.40.2-0.50.1-0.4-0.3-0.3-1.3-1.30.10.5-1.4-1.4-1.3
Pavlov. Cond. magazine entry latency0.10.20.30.5-0.00.50.50.40.50.50.40.4-0.50.4-0.50.40.50.30.50.40.40.10.20.2-0.3
Pavlov. Cond. change in total contacts0.00.00.20.1-0.10.10.10.10.10.20.10.2-0.30.3-0.30.30.30.1-0.1-0.10.2-0.2-0.3-0.3-0.4
Pavlov. Cond. index score0.40.50.80.70.20.80.90.70.70.80.70.7-0.70.8-0.70.70.70.60.90.90.50.10.60.60.2
Pavlov. Cond. latency score0.40.51.10.80.20.90.90.80.70.80.70.7-0.70.8-0.60.70.70.61.11.10.4-0.00.80.80.5
Pavlov. Cond. lever contacts0.20.31.10.3-0.30.50.60.30.20.20.10.2-0.00.3-0.00.20.20.10.90.9-0.2-0.51.01.11.0
Pavlov. Cond. magazine entry number0.50.61.0-0.9-0.4-1.0-1.0-0.8-0.9-0.9-0.9-0.90.9-0.80.8-0.8-0.8-0.7-1.0-0.9-0.8-0.3-0.6-0.50.1
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.10.5-0.3-0.40.0-0.0-0.00.1-0.0-0.1-0.0-0.10.10.10.2-0.8-0.60.20.3-1.0-1.1-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.40.60.10.60.60.60.60.60.60.6-0.60.6-0.60.60.60.50.50.60.50.20.20.2-0.1
Pavlov. Cond. response bias0.30.30.60.6-0.00.70.70.60.60.70.60.6-0.60.7-0.60.60.60.40.80.70.50.10.50.50.1
Pavlov. Cond. lever latency0.10.20.4-0.4-0.5-0.4-0.5-0.3-0.3-0.3-0.3-0.30.2-0.20.3-0.2-0.2-0.3-0.7-0.6-0.2-0.2-0.6-0.6-0.5
Pavlov. Cond. magazine entry latency0.40.51.9-0.2-0.50.00.1-0.4-0.4-0.4-0.5-0.40.5-0.50.5-0.6-0.6-0.60.80.7-0.7-0.91.31.31.4
Pavlov. Cond. change in total contacts0.30.51.00.71.00.80.80.80.70.70.60.8-0.80.8-0.80.80.80.80.70.90.50.40.40.30.3
Pavlov. Cond. index score0.20.20.70.50.40.50.60.40.40.30.30.3-0.20.2-0.20.20.20.30.80.80.20.10.90.80.7
Pavlov. Cond. latency score0.10.10.50.20.10.20.30.10.10.10.10.00.0-0.10.0-0.0-0.10.00.60.5-0.1-0.10.70.60.6
Pavlov. Cond. lever contacts0.40.50.90.81.00.80.80.70.80.70.70.7-0.70.6-0.70.70.60.80.90.90.60.60.60.60.3
Pavlov. Cond. magazine entry number0.20.31.4-0.1-0.0-0.3-0.4-0.0-0.0-0.00.10.0-0.10.1-0.00.20.20.2-0.8-0.80.30.4-1.2-1.1-1.0
Pavlov. Cond. intertrial magazine entries1.31.94.4-1.3-1.0-1.7-1.7-1.3-1.3-1.3-1.0-1.31.2-1.41.2-1.2-1.1-1.0-2.1-2.1-0.6-0.6-1.9-1.8-1.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.20.20.30.40.20.20.20.10.1-0.10.0-0.10.10.00.10.60.6-0.0-0.00.70.70.7
Pavlov. Cond. response bias0.40.62.10.60.60.80.90.50.50.50.40.5-0.30.4-0.40.40.30.31.31.30.10.01.41.41.2
Time in closed arm before self-admin1.41.82.71.51.41.41.41.51.61.61.61.6-1.51.5-1.61.61.61.50.80.81.61.0-0.1-0.2-0.7
Time in closed arm after self-admin0.80.91.51.20.71.21.21.11.01.01.20.9-0.60.7-0.70.80.81.01.21.10.90.51.00.80.5
Time in open arm before self-admin1.11.21.9-0.9-1.0-1.3-1.3-1.0-1.2-1.2-1.0-1.31.2-1.41.4-1.2-1.3-1.0-1.2-1.3-0.8-0.4-0.4-0.6-0.2
Time in open arm after self-admin0.10.10.5-0.4-0.2-0.2-0.1-0.3-0.3-0.3-0.6-0.20.30.10.2-0.2-0.2-0.30.10.2-0.7-0.50.30.50.5
Bone: periosteal estimation0.10.20.60.50.00.50.60.50.40.40.50.4-0.40.5-0.30.40.40.40.60.80.30.20.60.50.6
Bone: periosteal perimeter0.30.61.10.90.70.80.80.90.90.91.00.8-0.80.7-0.80.80.80.80.50.70.91.00.0-0.0-0.2
Bone: post-yield work0.30.41.6-0.4-0.9-0.2-0.1-0.4-0.4-0.4-0.4-0.50.7-0.40.7-0.5-0.5-0.50.40.3-0.7-0.80.80.91.3
Progressive ratio test 1 active lever presses0.20.31.20.1-0.3-0.5-0.50.0-0.2-0.20.1-0.20.4-0.20.9-0.2-0.10.1-0.8-0.80.30.2-0.8-1.0-1.1
Progressive ratio test 1 breakpoint0.20.31.40.2-0.1-0.3-0.40.2-0.1-0.00.3-0.00.2-0.10.7-0.10.00.3-0.7-0.70.50.3-0.8-1.1-1.2
Progressive ratio test 1 inactive lever presses0.20.21.30.3-0.20.10.10.2-0.1-0.10.0-0.10.7-0.20.8-0.3-0.30.00.60.6-0.2-0.51.10.90.8
Progressive ratio test 2 active lever presses0.40.51.5-0.5-0.8-0.8-0.8-0.5-0.8-0.8-0.5-0.80.7-0.81.2-0.8-0.8-0.6-0.7-0.5-0.5-0.7-0.2-0.4-0.1
Progressive ratio test 2 breakpoint0.50.61.5-0.6-0.8-0.9-0.9-0.6-0.9-0.8-0.6-0.80.7-0.91.2-0.9-0.9-0.6-0.8-0.6-0.5-0.7-0.3-0.5-0.2
Progressive ratio test 2 inactive lever presses0.20.41.60.1-0.6-0.1-0.1-0.0-0.4-0.4-0.1-0.40.9-0.61.3-0.6-0.6-0.30.40.5-0.4-0.61.10.80.8
Incentive Sensitization - Responses0.30.51.3-0.8-0.7-0.6-0.6-0.7-0.8-0.8-0.9-0.70.4-0.60.5-0.7-0.8-0.9-0.20.2-1.0-1.20.30.40.8
Incentive Sensitization - Breakpoint0.50.71.6-0.9-0.8-0.7-0.7-0.9-0.9-0.9-1.0-0.80.5-0.70.7-0.9-0.9-1.0-0.30.2-1.1-1.30.40.50.9
Sum of active levers in priming session hrs 5-63.02.85.71.91.91.51.42.01.81.71.91.8-1.71.7-1.81.81.82.00.80.62.02.4-0.2-0.5-1.3
Progressive ratio0.91.44.5-1.2-0.8-1.3-1.4-1.1-0.9-0.9-0.9-0.80.6-0.70.4-0.7-0.6-0.6-2.0-1.8-0.4-0.4-2.1-1.9-1.7
Food seeking constrained by brief footshock0.20.30.8-0.4-0.3-0.6-0.7-0.6-0.6-0.6-0.5-0.70.1-0.90.3-0.7-0.7-0.6-0.6-0.4-0.30.1-0.2-0.3-0.5
Seeking ratio, punishment vs. effort0.30.42.30.60.20.60.60.50.20.20.30.1-0.3-0.0-0.00.0-0.00.11.11.00.10.31.51.31.0
Retroperitoneal fat weight0.20.81.7-0.8-1.3-1.0-1.0-0.8-1.0-1.0-0.7-1.01.2-1.11.2-1.0-1.0-0.8-0.7-0.7-0.8-1.0-0.1-0.20.3
Reaction time number correct0.81.53.1-1.5-1.8-1.4-1.4-1.4-1.3-1.3-1.4-1.21.0-1.21.1-1.2-1.2-1.2-1.4-1.1-1.1-1.3-0.9-0.7-0.2
Reaction time mean minus median0.51.32.21.31.51.21.21.31.21.21.21.2-1.31.2-1.21.21.21.21.21.11.11.10.50.4-0.1
Reaction time mean minus median AUC0.40.92.11.11.41.01.01.01.01.01.01.0-1.11.0-1.01.00.90.91.01.00.90.70.50.4-0.1
Reaction time num false alarms1.21.72.8-1.4-1.7-1.5-1.5-1.4-1.4-1.4-1.2-1.41.3-1.61.3-1.4-1.4-1.2-1.5-1.4-1.0-0.9-0.8-0.8-0.3
Reaction time num false alarms AUC1.62.64.3-1.8-2.1-1.8-1.8-1.8-1.7-1.7-1.6-1.81.7-1.81.6-1.7-1.7-1.6-1.7-1.6-1.4-1.2-0.9-0.8-0.1
Reaction time trials correct on left0.81.53.1-1.5-1.8-1.4-1.4-1.4-1.3-1.3-1.4-1.21.0-1.21.1-1.2-1.2-1.2-1.4-1.1-1.1-1.3-0.9-0.7-0.2
Reaction time trials on left0.71.42.9-1.4-1.7-1.3-1.3-1.4-1.3-1.2-1.3-1.20.9-1.11.1-1.2-1.1-1.1-1.4-1.1-1.1-1.2-0.9-0.7-0.2
Reaction time mean2.23.54.62.12.02.02.02.02.12.12.02.1-2.12.0-2.12.02.02.01.71.61.91.80.70.5-0.4
Reaction time mean AUC1.72.83.91.91.71.81.81.81.91.91.81.9-2.01.8-2.01.81.81.81.41.31.81.50.40.3-0.5
Median of all reaction times2.53.65.02.11.92.12.12.12.22.12.12.1-2.22.1-2.22.12.12.01.71.62.01.80.60.4-0.5
Reaction time omissions0.40.61.20.81.00.80.90.80.70.70.60.7-0.70.8-0.60.70.60.51.01.10.40.40.80.80.5
Reaction time false alarm rate0.60.81.3-0.9-1.1-0.9-1.0-0.9-0.9-1.0-0.8-1.01.1-1.11.0-1.0-1.0-0.9-0.8-0.9-0.8-0.5-0.3-0.30.1
Reaction time premature initiation rate0.10.10.30.40.40.40.40.30.30.30.40.20.00.1-0.30.20.20.20.50.50.30.50.50.50.3
Reaction time premature initiations0.00.00.2-0.2-0.4-0.2-0.1-0.3-0.2-0.2-0.2-0.30.3-0.30.1-0.3-0.3-0.2-0.10.0-0.2-0.00.10.10.2
Std. dev. reaction times0.91.72.91.41.71.51.51.41.41.41.31.4-1.51.5-1.51.41.41.31.41.41.11.30.70.70.1
Reaction time trials completed0.71.42.9-1.4-1.7-1.3-1.3-1.4-1.3-1.2-1.3-1.20.9-1.11.1-1.2-1.1-1.1-1.4-1.1-1.1-1.2-0.9-0.7-0.2
Reaction time trials AUC0.71.32.6-1.4-1.6-1.3-1.3-1.3-1.2-1.2-1.3-1.10.9-1.11.0-1.1-1.1-1.1-1.3-1.0-1.1-1.2-0.9-0.7-0.2
Run reversals in cocaine runway, females0.60.61.5-1.0-1.0-0.8-0.8-1.0-0.7-0.7-0.7-0.81.2-0.90.7-0.8-0.7-0.8-0.9-0.9-0.6-0.6-0.7-0.50.2
Run reversals in cocaine runway, males0.20.20.80.60.3-0.0-0.10.40.10.10.7-0.10.1-0.60.1-0.1-0.10.3-0.0-0.40.70.9-0.1-0.4-0.5
Latency to leave start box in cocaine runway1.92.24.0-1.5-2.0-1.3-1.2-1.5-1.6-1.5-1.5-1.61.9-1.61.8-1.7-1.7-1.6-0.6-0.6-1.7-2.00.50.60.9
Latency to leave start box in cocaine runway, F1.21.42.2-1.1-1.3-0.7-0.7-1.2-1.1-1.1-1.2-1.21.5-1.21.3-1.3-1.3-1.4-0.10.0-1.5-1.21.01.21.4
Latency to leave start box in cocaine runway, M2.82.65.0-1.6-2.2-1.8-1.8-1.5-1.7-1.7-1.5-1.71.8-1.71.8-1.7-1.6-1.5-1.5-1.5-1.4-2.2-0.8-0.7-0.3
Std. dev. time between licks in bursts0.40.51.4-0.8-1.0-0.9-0.9-0.7-0.6-0.6-0.7-0.60.6-0.40.5-0.5-0.5-0.4-1.2-1.0-0.50.1-1.1-1.0-0.6
Total sessions with >9 infusions0.10.20.70.0-0.4-0.4-0.4-0.0-0.2-0.20.0-0.20.3-0.30.7-0.2-0.2-0.0-0.5-0.50.2-0.1-0.5-0.7-0.8
Short access day 1 total inactive lever presses0.50.61.9-0.5-1.2-0.7-0.6-0.6-0.8-0.8-0.6-0.81.2-1.01.4-1.0-0.9-0.8-0.1-0.2-0.6-0.60.40.30.5
Short access day 10 total inactive lever presses0.10.31.10.40.00.50.50.30.20.20.30.1-0.10.0-0.20.10.1-0.01.00.90.10.11.01.00.9
Short access day 1 total infusions0.50.72.4-0.4-1.1-0.9-0.9-0.5-0.8-0.8-0.5-0.81.2-0.91.6-0.9-0.9-0.6-0.7-0.9-0.3-0.4-0.3-0.6-0.4
Short access day 10 total infusions1.51.97.11.31.10.50.41.31.11.21.61.1-1.20.9-0.71.21.31.5-0.5-0.62.01.9-1.8-2.1-2.7
Short access total infusions0.40.52.90.70.30.10.00.70.50.50.90.5-0.30.40.10.50.60.7-0.4-0.61.10.7-1.0-1.3-1.7
Short access day 1 locomotion1.01.22.6-1.0-1.4-1.2-1.2-1.1-1.2-1.2-1.0-1.21.5-1.31.6-1.2-1.2-1.0-1.0-1.2-0.9-1.0-0.5-0.5-0.0
Short access day 10 total locomotion0.00.00.20.40.00.00.00.40.10.10.40.1-0.20.1-0.00.10.10.2-0.00.00.40.0-0.1-0.3-0.5
Short access total locomotion1.01.21.8-1.1-1.3-1.3-1.3-1.0-1.2-1.2-1.0-1.21.0-1.31.2-1.2-1.2-1.1-1.2-1.0-0.8-1.3-0.7-0.7-0.3
One hour access (0.3 mA shock)3.33.86.92.22.21.51.42.22.02.12.52.0-2.01.9-1.52.12.12.30.30.52.62.5-1.0-1.4-2.4
Compulsive drug intake0.40.51.1-1.0-0.6-0.7-0.7-1.0-0.8-0.8-1.0-0.80.7-0.70.3-0.7-0.7-0.8-0.6-0.5-0.9-0.4-0.20.00.4
One hour access (shock baseline)1.82.85.22.01.81.41.32.01.81.82.21.8-1.61.7-1.21.81.82.00.50.62.31.9-0.6-1.0-1.9
Social response proportion0.60.61.21.10.50.90.91.00.90.91.10.8-0.60.8-0.50.80.81.00.80.51.00.60.40.2-0.5
Social responses1.41.93.11.81.11.51.51.71.51.51.61.5-1.41.4-1.31.41.41.61.21.31.51.20.60.4-0.4
Social time4.15.68.32.71.82.82.92.72.62.62.62.5-2.22.4-2.12.42.42.42.82.92.11.71.91.70.8
Soleus weight1.33.95.4-2.3-2.3-2.2-2.2-2.2-2.2-2.2-2.2-2.12.2-2.02.2-2.1-2.1-2.1-1.8-1.9-2.0-1.6-0.9-0.70.1
Bone: stiffness0.81.33.1-1.0-1.5-0.6-0.5-0.9-1.0-1.0-1.2-1.01.3-0.81.4-1.1-1.1-1.10.20.2-1.5-1.71.11.21.8
Tibialis anterior weight3.511.916.4-3.8-3.4-4.0-4.0-3.8-3.8-3.8-3.6-3.83.5-3.83.5-3.7-3.6-3.6-3.7-3.7-3.0-2.5-2.2-2.0-0.6
Time to tail flick, vehicle, before self-admin0.90.91.81.01.11.00.91.01.01.00.91.1-1.31.2-1.21.11.11.10.70.70.90.70.0-0.0-0.4
Time to tail flick, vehicle, after self-admin0.30.40.80.40.60.70.70.60.70.70.50.7-0.90.8-0.80.80.70.50.50.70.4-0.10.10.20.1
Time to tail flick, test, before self-admin3.43.65.9-2.1-1.8-2.2-2.2-2.1-1.9-1.9-1.8-2.01.9-2.11.8-1.9-1.8-1.7-2.4-2.4-1.4-1.2-1.8-1.6-0.6
Time to tail flick, test, after self-admin0.50.61.3-0.8-0.7-0.8-0.8-0.8-0.7-0.7-0.6-0.60.8-0.60.8-0.6-0.6-0.5-1.0-1.1-0.5-0.8-0.9-0.8-0.4
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.5-0.4-0.2-0.2-0.4-0.3-0.3-0.4-0.30.4-0.20.3-0.2-0.2-0.4-0.1-0.1-0.4-0.5-0.10.00.1
Delta time to tail flick, test, before/after SA1.31.42.01.31.11.41.41.41.21.21.21.3-1.11.4-1.01.31.21.21.41.30.90.60.90.80.2
Tibia length0.30.93.10.70.21.11.10.80.70.70.50.8-0.61.0-0.60.80.70.61.41.80.1-0.41.51.51.4
Ambulatory time before self-admin0.71.12.11.10.91.31.31.11.11.11.01.2-0.81.3-0.91.11.11.01.51.10.70.60.90.90.3
Ambulatory time after self-admin1.11.35.21.10.31.21.21.00.70.70.60.7-0.30.7-0.30.50.40.52.11.80.1-0.02.32.11.6
Bone: tissue strength0.10.10.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.20.2-0.20.2-0.2-0.2-0.2-0.3-0.2-0.3-0.4-0.2-0.10.1
Total heroin consumption3.44.08.02.22.31.51.42.22.02.02.42.0-2.41.7-2.22.02.12.30.30.42.72.8-1.0-1.3-2.3
Bone: trabecular number2.84.69.42.21.62.62.72.22.22.11.92.1-1.92.1-1.92.01.91.83.03.11.31.12.52.41.7
Bone: trabecular spacing2.12.83.9-1.8-1.6-2.0-2.0-1.8-1.9-1.8-1.7-1.81.9-1.81.9-1.8-1.8-1.6-1.7-1.9-1.5-1.7-1.0-1.0-0.4
Bone: trabecular thickness4.86.08.52.62.22.92.92.62.72.72.52.7-2.72.7-2.72.62.52.42.72.92.01.81.71.60.7
Bone: trabecular tissue density0.60.91.7-0.9-0.7-0.7-0.7-1.0-1.0-1.0-1.1-1.01.1-1.01.1-1.1-1.1-1.0-0.1-0.1-1.3-1.20.70.81.1
Water consumed over 24 hours0.10.10.30.40.50.30.30.40.40.40.50.4-0.30.4-0.40.50.50.50.10.10.50.2-0.3-0.3-0.4
Number of responses in last shaping day0.10.10.40.50.30.40.30.40.30.30.30.3-0.50.2-0.30.20.20.10.50.60.30.20.40.3-0.0