Mrps9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb intron excision ratio chr9_45170461_45172088 0.21 0.13 4.3e-03 0.03 0.04 0.04 0 6.8e-02 5.2e-02 3.9e-02 3.2e-01
2 pVTA gene expression Mrps9 0.14 0.1 3.3e-03 0.08 0.04 0.01 0.06 2.8e-04 5.1e-03 1.3e-01 2.0e-03
3 Liver mRNA stability Mrps9 0.15 0.08 3.7e-14 0.05 0.08 0.07 0.08 2.9e-06 4.2e-09 1.1e-08 8.4e-09
4 PL mRNA stability Mrps9 0.35 0.13 0.0e+00 0.23 0.24 0.23 0.24 2.7e-25 7.3e-26 1.4e-25 9.6e-27
5 Brain mRNA stability Mrps9 0.32 0.12 0.0e+00 0.25 0.29 0.28 0.28 1.9e-23 8.8e-27 4.2e-26 5.1e-26
6 IL mRNA stability Mrps9 0.4 0.18 2.8e-04 0.09 0.11 0.08 0.1 3.8e-03 1.1e-03 5.9e-03 2.1e-03
7 PL intron excision ratio chr9_45166282_45170292 0.06 0.04 8.9e-05 0.03 0.03 0.01 0.03 1.4e-04 2.7e-04 3.2e-02 4.4e-04
8 BLA mRNA stability Mrps9 0.33 0.13 7.4e-12 0.22 0.2 0.2 0.2 9.8e-12 5.9e-11 5.8e-11 6.2e-11
9 pVTA mRNA stability Mrps9 0.19 0.13 7.2e-04 0.07 0.05 0.01 0.04 7.3e-04 4.5e-03 8.8e-02 7.5e-03
10 NAcc mRNA stability Mrps9 0.29 0.1 0.0e+00 0.21 0.24 0.23 0.23 5.8e-24 2.0e-27 2.6e-26 1.6e-26
11 OFC mRNA stability Mrps9 0.37 0.23 6.1e-03 0.08 0.06 0.02 0.04 6.7e-03 1.9e-02 8.7e-02 4.0e-02
12 PL intron excision ratio chr9_45170461_45172088 0.15 0.07 6.4e-13 0.11 0.11 0.09 0.11 3.8e-12 2.3e-12 1.9e-10 6.1e-12
13 Liver gene expression Mrps9 0.2 0.11 0.0e+00 0.13 0.13 0.13 0.13 2.6e-14 3.2e-14 5.8e-14 2.6e-14
14 Adipose gene expression Mrps9 0.14 0.07 1.7e-16 0.09 0.09 0.08 0.08 4.4e-10 5.2e-10 7.8e-09 5.6e-09
15 Adipose mRNA stability Mrps9 0.44 0.12 0.0e+00 0.25 0.27 0.28 0.26 1.3e-27 3.2e-30 1.7e-30 3.3e-29
16 Liver intron excision ratio chr9_45166282_45170292 0.11 0.06 1.9e-07 0.05 0.04 0.01 0.04 5.6e-06 1.7e-05 1.4e-02 2.4e-05
17 LHb mRNA stability Mrps9 0.26 0.15 5.9e-03 0.02 0.05 0.01 0.02 1.4e-01 2.6e-02 2.1e-01 9.5e-02
18 NAcc intron excision ratio chr9_45170461_45172088 0.15 0.08 4.3e-10 0.06 0.07 0.06 0.06 4.1e-07 3.3e-08 1.1e-07 3.9e-07
19 NAcc gene expression Mrps9 0.03 0.02 4.9e-04 0.02 0.02 0.02 0.02 9.3e-04 7.7e-04 6.9e-04 2.0e-03
20 NAcc intron excision ratio chr9_45166282_45170292 0.06 0.05 2.9e-03 0 0.01 0 0 2.7e-01 6.0e-02 1.1e-01 2.4e-01
21 PL gene expression Mrps9 0.04 0.03 1.8e-04 0.02 0.03 0.02 0.02 1.0e-03 2.2e-04 2.9e-03 3.2e-03
22 Brain gene expression Mrps9 0.08 0.05 8.9e-05 0.06 0.03 0.04 0.04 6.6e-06 4.8e-04 1.6e-04 6.4e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density3.15.110.9-3.12.22.82.52.32.32.2-2.0-2.02.0-1.92.13.3-2.9-2.3-2.01.81.4-2.8-0.72.2-1.4
Area under the delay curve1.21.24.50.80.70.20.60.70.70.9-1.1-1.10.9-0.90.9-1.10.8-0.5-1.11.21.31.3-1.6-1.92.1
BMI with tail1.34.27.72.8-2.1-2.5-2.2-2.2-2.2-2.31.81.8-2.02.1-2.1-2.52.52.01.8-1.9-1.72.41.1-1.40.6
BMI without tail0.10.10.3-0.10.50.30.40.40.40.3-0.6-0.60.3-0.20.40.3-0.0-0.4-0.40.40.3-0.1-0.2-0.10.3
Body weight0.00.20.90.5-0.6-0.3-0.2-0.4-0.4-0.80.30.3-0.31.0-0.40.00.30.50.3-0.5-0.40.40.40.2-0.3
Weight adjusted by age2.93.26.20.8-2.5-1.6-1.8-1.9-1.9-2.22.22.2-2.02.1-2.0-0.90.61.72.1-2.2-2.10.12.00.9-1.6
Bone surface0.40.72.5-0.90.81.01.00.80.90.8-0.7-0.70.7-0.60.81.6-0.9-0.9-0.70.70.3-0.9-0.00.9-0.5
Bone volume1.62.76.7-2.01.72.01.91.71.81.7-1.4-1.41.5-1.31.62.6-2.0-1.8-1.41.31.0-1.9-0.51.6-1.0
Breakpoint value in progressive ratio session0.91.01.8-0.61.31.11.31.00.80.8-1.3-1.31.4-0.31.00.8-0.9-1.1-1.21.01.3-0.4-1.30.10.4
Number of licking bursts0.30.41.4-0.10.60.50.60.70.80.7-0.6-0.60.6-1.20.70.10.1-0.6-0.60.80.60.0-0.6-0.50.7
Context. condit. distance diff. score0.70.92.6-1.50.71.11.00.90.90.6-0.6-0.60.7-0.60.71.5-1.4-0.5-0.70.50.3-1.60.11.3-0.9
Locomotion velocity, session 10.00.00.10.10.20.10.10.10.20.2-0.1-0.10.1-0.20.1-0.10.00.1-0.10.20.10.1-0.1-0.20.1
Locomotion distance, session 11.51.93.31.2-1.6-1.4-1.5-1.5-1.6-1.61.51.5-1.41.8-1.6-1.21.11.71.5-1.6-1.40.81.20.0-0.5
Locomotion velocity, session 23.13.65.32.3-2.0-2.3-2.1-2.1-2.1-2.02.02.0-2.01.9-2.0-1.82.22.02.0-1.9-1.81.91.3-1.00.3
Locomotion distance, session 21.92.64.52.1-1.7-2.0-1.8-1.7-1.8-1.61.51.5-1.61.7-1.6-1.92.01.71.5-1.5-1.31.80.8-1.20.6
Locomotion velocity, session 30.10.10.5-0.2-0.20.10.0-0.1-0.1-0.20.10.1-0.10.4-0.20.5-0.5-0.10.1-0.3-0.3-0.40.40.7-0.7
Locomotion distance, session 30.10.10.3-0.30.10.20.20.10.00.0-0.3-0.30.20.00.10.3-0.5-0.3-0.20.00.1-0.4-0.10.3-0.3
Stereotopy head waving bouts, day 30.40.50.7-0.70.80.70.80.70.70.8-0.6-0.60.8-0.80.70.6-0.6-0.5-0.70.70.8-0.5-0.70.00.2
Stereotopy head waving duration, day 30.20.30.6-0.30.70.50.60.60.50.7-0.5-0.50.7-0.70.60.3-0.2-0.2-0.60.70.7-0.1-0.7-0.30.5
Locomotion velocity, session 72.73.04.51.0-1.8-1.7-1.8-1.9-1.8-2.02.02.0-2.12.0-2.0-0.81.11.92.0-2.0-2.10.42.10.4-1.0
Locomotion distance, session 70.81.11.51.0-1.1-1.2-1.1-1.1-1.0-1.21.01.0-1.21.2-1.1-1.01.21.21.1-1.0-1.10.71.0-0.40.1
Stereotopy head waving bouts, day 70.10.10.3-0.40.30.40.40.30.10.4-0.4-0.40.5-0.30.30.5-0.4-0.0-0.40.30.5-0.3-0.50.10.1
Stereotopy head waving duration, day 70.20.20.8-0.6-0.20.20.1-0.1-0.2-0.20.20.2-0.10.2-0.20.8-0.70.30.1-0.3-0.3-0.70.40.9-0.9
Locomotion velocity, session 81.01.23.0-0.0-1.2-0.5-0.9-1.0-0.9-1.21.21.2-1.11.2-1.10.4-0.20.81.2-1.3-1.5-0.61.71.4-1.7
Locomotion distance, session 80.91.32.40.5-1.4-0.9-1.0-1.1-1.0-1.31.31.3-1.31.4-1.2-0.20.31.11.3-1.3-1.5-0.11.50.9-1.2
Degree of sensitization distance0.91.02.51.3-0.7-1.2-0.9-0.9-0.7-0.80.70.7-0.90.7-0.7-1.41.61.10.8-0.5-0.61.30.4-1.31.0
Degree of sensitization stereotypy0.10.10.4-0.4-0.00.30.1-0.0-0.10.00.00.00.10.1-0.00.6-0.50.1-0.0-0.2-0.0-0.40.10.7-0.6
Conditioned locomotion1.41.72.4-1.21.51.41.41.41.31.5-1.4-1.41.5-1.41.41.0-1.2-1.3-1.41.31.5-0.7-1.40.20.2
Cocaine response after cond. corrected0.50.62.60.90.7-0.20.20.30.40.6-0.6-0.60.4-0.40.5-0.70.9-0.1-0.60.70.61.1-0.9-1.51.6
Cocaine response after cond. not corrected0.20.31.20.80.2-0.30.00.10.10.2-0.3-0.30.10.00.2-0.60.80.1-0.30.30.30.9-0.5-1.01.1
Cocaine response before conditioning0.81.02.1-0.1-1.5-0.5-0.7-0.9-1.0-1.31.01.0-0.91.4-1.00.0-0.20.81.0-1.2-1.0-0.41.11.1-1.3
Saline control response0.60.81.7-0.0-0.9-0.6-0.8-0.9-0.8-0.91.11.1-1.00.9-1.00.20.11.11.1-1.1-1.2-0.21.30.8-1.2
Bone: connectivity density1.01.53.4-1.41.41.51.51.31.41.4-1.2-1.21.2-1.11.31.8-1.2-1.2-1.21.20.9-1.2-0.60.8-0.3
Bone: cortical apparent density5.26.89.72.1-3.0-2.7-2.8-2.9-2.9-3.03.03.0-2.93.1-3.0-1.92.02.73.0-3.0-2.81.42.50.2-1.1
Bone: cortical area0.10.10.30.2-0.2-0.1-0.1-0.3-0.3-0.20.30.3-0.20.5-0.30.40.00.20.3-0.4-0.30.10.30.4-0.5
Bone: cortical porosity0.70.71.7-1.00.81.01.00.90.90.9-0.7-0.70.8-0.80.91.3-1.1-0.9-0.80.70.6-0.9-0.30.7-0.3
Bone: cortical porosity0.70.82.4-1.20.71.11.00.90.90.7-0.6-0.60.6-0.70.81.5-1.4-0.9-0.70.60.3-1.30.01.1-0.7
Bone: cortical thickness0.10.20.40.3-0.2-0.2-0.3-0.4-0.4-0.30.60.6-0.40.6-0.40.40.20.40.5-0.5-0.50.10.50.5-0.7
Bone: cortical thickness0.00.00.2-0.10.10.10.10.00.10.00.00.0-0.00.20.10.5-0.20.10.0-0.0-0.2-0.20.30.3-0.3
Bone: cortical tissue density5.16.79.72.0-2.9-2.7-2.8-2.9-2.9-3.03.03.0-2.93.1-2.9-1.81.92.73.0-2.9-2.81.42.50.2-1.1
Condit. Reinf. active minus inactive responses0.40.41.40.50.60.10.30.40.20.5-0.4-0.40.6-0.50.4-0.60.70.3-0.50.60.91.0-1.2-1.11.2
Condit. Reinf. active-inactive response ratio0.40.41.30.00.80.30.50.60.40.7-0.6-0.60.7-0.70.6-0.40.40.2-0.70.71.00.6-1.1-0.91.0
Condit. Reinf. active responses0.10.20.60.50.2-0.10.00.0-0.10.1-0.1-0.10.2-0.10.1-0.50.60.5-0.10.20.40.8-0.6-0.70.7
Condit. Reinf. inactive responses0.50.60.91.0-0.9-0.9-0.8-0.9-0.9-0.90.70.7-0.70.9-0.8-0.80.90.80.8-0.8-0.70.60.5-0.40.2
Incentive salience index mean0.10.10.30.20.40.20.30.30.30.4-0.2-0.20.4-0.40.30.00.30.2-0.40.40.50.5-0.5-0.30.4
Condit. Reinf. lever presses0.20.31.3-0.60.00.50.30.20.2-0.00.10.10.00.10.11.0-0.6-0.00.0-0.1-0.3-0.70.61.2-1.1
Condit. Reinf. active minus inactive responses0.80.91.9-0.71.10.91.01.00.91.1-1.2-1.21.2-1.11.00.3-0.6-0.8-1.11.11.3-0.2-1.4-0.50.8
Condit. Reinf. active-inactive response ratio2.02.12.8-1.31.61.61.51.61.51.6-1.6-1.61.7-1.61.60.9-1.3-1.6-1.61.51.7-0.8-1.50.10.3
Condit. Reinf. active responses0.20.31.00.10.30.00.30.30.20.4-0.6-0.60.5-0.40.4-0.30.2-0.1-0.50.50.70.4-0.9-0.91.0
Condit. Reinf. inactive responses1.11.32.11.0-1.4-1.4-1.2-1.3-1.2-1.41.11.1-1.31.3-1.2-1.01.21.41.1-1.1-1.20.81.0-0.50.3
Condit. Reinf. lever presses0.20.20.5-0.70.50.50.50.40.30.5-0.6-0.60.5-0.50.40.4-0.5-0.3-0.60.40.5-0.3-0.5-0.00.2
Condit. Reinf. lever reinforcers received0.20.31.50.30.2-0.10.20.20.10.3-0.5-0.50.4-0.30.3-0.60.40.0-0.50.40.60.7-0.9-1.21.2
Conditioned reinforcement - actives0.30.31.00.10.40.20.40.50.40.0-0.6-0.60.6-0.50.5-0.20.2-0.7-0.60.60.80.4-1.0-0.81.0
Conditioned reinforcement - inactives0.20.20.8-0.9-0.30.40.40.3-0.0-0.4-0.4-0.40.50.60.10.2-0.6-0.3-0.40.10.5-0.8-0.50.4-0.0
Conditioned locomotion0.20.31.10.4-0.9-0.6-0.4-0.6-0.7-1.00.40.4-0.41.0-0.7-0.40.3-0.10.3-0.6-0.30.40.2-0.20.1
Patch foraging indifference point 0 sec0.91.52.30.7-1.5-1.1-1.2-1.3-1.4-1.41.51.5-1.41.4-1.4-0.30.51.01.3-1.5-1.50.31.50.7-0.9
Patch foraging indifference point AUC0.30.31.40.5-0.5-0.5-0.6-0.4-0.5-0.50.20.2-0.10.3-0.3-1.20.90.30.1-0.20.10.9-0.4-0.90.6
Delay disc. indifference point, 0s delay1.11.22.30.7-1.5-1.1-1.1-1.1-1.0-1.51.21.2-1.31.2-1.2-0.80.81.01.1-1.2-1.40.41.30.2-0.5
Delay disc. indifference point, 16s delay2.32.33.6-0.41.71.11.51.61.71.9-1.8-1.81.7-1.81.70.0-0.3-1.3-1.81.91.80.1-1.9-1.21.8
Delay disc. indifference point, 2s delay0.40.41.70.60.4-0.00.30.30.20.2-0.6-0.60.5-0.20.4-0.70.6-0.5-0.70.50.80.8-1.0-1.21.3
Delay disc. indifference point, 24s delay0.10.10.4-0.10.30.20.30.40.40.4-0.4-0.40.3-0.50.4-0.3-0.1-0.1-0.30.50.40.1-0.4-0.40.6
Delay disc. indifference point, 4s delay0.30.30.90.9-0.7-0.6-0.4-0.4-0.3-0.50.30.3-0.40.4-0.3-0.90.80.60.2-0.2-0.30.90.1-0.70.5
Delay disc. indifference point, 8s delay0.70.82.60.70.70.10.40.60.51.0-0.9-0.90.7-0.70.7-0.80.7-0.4-0.70.91.01.1-1.3-1.51.6
Indifference point function ln k0.71.02.01.4-0.9-1.3-1.2-1.1-0.9-0.81.01.0-1.30.6-1.0-0.91.21.01.1-0.9-1.21.01.0-0.70.3
Indifference point function log k0.71.02.01.4-0.9-1.3-1.2-1.1-0.9-0.81.01.0-1.30.6-1.0-0.91.21.01.1-0.9-1.21.01.0-0.70.3
Patch foraging total patch changes 0 sec0.71.01.90.8-1.4-1.0-1.0-1.2-1.2-1.21.31.3-1.21.1-1.2-0.50.60.81.1-1.3-1.20.51.10.3-0.4
Patch foraging total patch changes 12 sec0.40.51.9-0.6-0.9-0.1-0.3-0.5-0.6-0.90.60.6-0.41.1-0.60.4-0.50.30.5-0.8-0.7-0.70.81.3-1.4
Patch foraging total patch changes 18 sec0.50.61.60.9-0.8-0.9-1.0-0.8-1.0-0.70.70.7-0.60.6-0.8-1.31.20.60.7-0.7-0.31.1-0.0-0.80.5
Patch foraging total patch changes 24 sec0.60.81.6-0.1-1.2-0.6-0.9-0.9-1.0-1.11.11.1-0.91.3-1.0-0.30.10.60.9-1.1-1.0-0.21.00.7-0.9
Patch foraging total patch changes 6 sec0.20.40.7-0.0-0.8-0.5-0.7-0.7-0.8-0.70.70.7-0.60.8-0.8-0.40.20.40.6-0.8-0.60.00.50.4-0.5
Patch foraging time to switch 0 sec0.30.41.3-1.10.50.80.60.50.50.4-0.3-0.30.4-0.10.41.0-1.1-0.5-0.20.20.1-1.10.11.1-0.9
Patch foraging water rate 0 sec0.30.42.10.9-0.0-0.4-0.1-0.1-0.10.1-0.4-0.40.2-0.40.1-0.90.90.0-0.50.30.51.2-0.8-1.41.4
Patch foraging water rate 12 sec0.10.21.00.60.1-0.4-0.4-0.2-0.10.20.10.1-0.1-0.5-0.1-0.60.7-0.10.00.10.10.8-0.3-1.01.0
Patch foraging water rate 18 sec0.00.00.10.10.0-0.10.1-0.1-0.20.10.10.10.10.0-0.10.30.10.2-0.0-0.00.20.3-0.3-0.20.3
Patch foraging water rate 24 sec0.10.10.40.6-0.0-0.5-0.4-0.3-0.30.10.20.2-0.4-0.0-0.3-0.30.50.50.2-0.2-0.20.60.1-0.60.4
Patch foraging water rate 6 sec0.30.51.81.3-0.3-0.6-0.5-0.3-0.3-0.20.20.2-0.2-0.5-0.2-1.01.10.00.10.10.11.4-0.4-1.41.3
Seeking ratio, delayed vs. immediate footshock0.80.92.2-1.30.31.21.01.01.00.3-0.9-0.90.9-0.70.91.1-1.5-0.9-0.90.70.7-1.2-0.41.0-0.7
Distance traveled before self-admin0.30.30.8-0.50.40.70.60.70.80.3-0.6-0.60.5-0.40.60.5-0.7-0.9-0.60.50.2-0.80.10.6-0.3
Distance traveled after self-admin1.61.86.2-2.10.61.51.11.01.00.4-0.7-0.70.7-0.00.72.0-2.3-1.3-0.60.30.1-2.20.52.5-2.0
Extensor digitorum longus weight6.826.636.45.8-5.2-6.0-5.9-5.7-5.7-5.35.55.5-5.45.2-5.5-5.45.75.75.5-5.1-4.74.83.6-2.50.7
Bone: elastic displacement1.11.22.2-0.41.50.91.11.21.11.4-1.3-1.31.2-1.21.20.5-0.6-1.4-1.31.31.3-0.1-1.3-0.50.8
Bone: elastic work0.81.01.7-0.81.31.21.11.11.11.2-1.0-1.01.0-0.91.11.2-1.0-1.2-1.01.00.9-0.7-0.70.4-0.1
Bone: endosteal estimation0.10.20.5-0.30.30.50.60.60.60.4-0.6-0.60.5-0.50.60.3-0.5-0.7-0.60.60.4-0.3-0.3-0.00.2
Bone: endosteal perimeter0.10.10.2-0.10.20.40.40.40.30.2-0.4-0.40.5-0.40.40.2-0.4-0.4-0.40.40.4-0.0-0.4-0.00.2
Epididymis fat weight0.10.10.60.8-0.4-0.3-0.2-0.4-0.5-0.50.20.2-0.20.7-0.4-0.30.30.10.2-0.3-0.10.7-0.0-0.1-0.1
Delta time in closed arm before/after self-admin0.00.00.4-0.00.2-0.1-0.1-0.2-0.30.20.00.0-0.00.7-0.2-0.10.2-0.00.0-0.20.10.1-0.2-0.10.0
Delta time in open arm before/after self-admin0.40.41.7-0.40.30.60.60.71.00.8-0.5-0.50.4-1.30.70.7-0.4-0.6-0.50.70.2-0.60.10.3-0.1
Diff in mean of infusions in LGA sessions1.61.83.8-1.02.01.41.51.51.31.5-1.5-1.51.6-1.21.51.1-1.0-1.4-1.51.41.6-0.6-1.40.10.5
Delay discount exponential model param1.31.44.6-0.8-0.8-0.3-0.7-0.9-0.8-1.11.21.2-1.11.1-1.01.0-0.70.61.2-1.3-1.5-1.21.71.8-2.1
Extinction: sum of active levers before priming3.03.04.3-1.51.82.02.02.01.91.7-2.0-2.02.1-1.51.91.5-1.5-2.1-2.01.81.9-1.1-1.60.40.3
Active lever presses in extinction session 61.01.03.41.00.80.10.60.50.30.5-1.0-1.01.0-0.40.6-0.90.9-0.5-1.00.91.31.3-1.7-1.61.9
Bone: final force0.30.51.10.1-0.8-0.3-0.5-0.6-0.6-0.80.70.7-0.70.9-0.70.4-0.10.50.7-0.8-0.9-0.31.10.9-1.1
Bone: final moment0.30.41.00.2-0.7-0.4-0.5-0.6-0.6-0.70.70.7-0.70.8-0.70.3-0.00.60.6-0.8-0.9-0.21.00.8-0.9
Food consumed during 24 hour testing period0.20.30.90.6-0.7-0.6-0.4-0.4-0.5-0.60.20.2-0.30.6-0.4-1.00.70.50.2-0.3-0.20.6-0.0-0.70.6
Glucose0.50.81.3-0.61.10.80.91.01.01.1-0.9-0.91.0-1.21.00.2-0.4-0.9-1.01.11.1-0.2-1.1-0.40.7
Heart weight0.40.62.11.2-0.5-0.8-0.5-0.5-0.5-0.60.60.6-0.40.8-0.4-1.21.40.60.4-0.3-0.21.2-0.0-1.00.8
Delay discount hyperbolic model param1.01.04.1-1.1-0.50.1-0.3-0.5-0.4-0.70.80.8-0.70.7-0.61.3-1.00.20.8-0.9-1.1-1.41.41.9-2.0
Intermittent access intake day 1-15 change0.10.10.5-0.7-0.3-0.1-0.1-0.1-0.0-0.40.20.2-0.30.0-0.20.3-0.3-0.10.2-0.2-0.4-0.60.50.3-0.3
Intermittent access intake escalation0.20.21.2-1.10.10.40.40.30.40.0-0.1-0.10.2-0.30.30.7-0.6-0.3-0.10.20.0-0.90.20.5-0.3
Intermittent access intake escalation 20.20.21.1-1.00.10.50.50.50.50.3-0.4-0.40.5-0.40.50.5-0.6-0.4-0.40.40.4-0.8-0.30.3-0.1
Intermitt. access day 1 inactive lever presses0.50.62.0-1.20.10.90.70.60.60.2-0.6-0.60.50.10.51.1-1.2-0.9-0.50.30.2-1.40.01.1-0.8
Intermitt. access day 15 inactive lever presses0.20.31.0-0.3-0.6-0.0-0.2-0.3-0.4-0.50.50.5-0.40.5-0.50.3-0.50.10.4-0.6-0.5-0.50.71.0-1.0
Intermitt. access escalation Index0.10.00.30.5-0.2-0.1-0.2-0.2-0.30.10.10.1-0.1-0.1-0.1-0.30.00.50.1-0.2-0.10.30.00.1-0.2
Intermittent access day 1 total infusions1.71.95.2-0.21.40.91.41.31.01.0-1.7-1.71.8-0.71.4-0.0-0.1-1.4-1.71.52.10.4-2.3-1.32.0
Intermittent access day 15 total infusions1.11.22.5-0.91.10.91.21.21.00.7-1.3-1.31.4-0.71.20.4-0.6-1.3-1.41.31.5-0.3-1.6-0.61.3
Intermittent access terminal intake (last 3 days)0.90.92.6-0.60.70.71.00.90.70.3-1.2-1.21.3-0.20.90.0-0.3-1.3-1.21.01.5-0.0-1.6-0.91.4
Intermittent access total infusions1.51.63.9-0.51.30.91.31.31.10.8-1.5-1.51.6-0.71.30.2-0.2-1.5-1.61.51.80.1-2.0-1.11.8
Intermittent access day 1 locomotion0.10.10.3-0.10.20.30.40.40.30.0-0.5-0.50.50.30.30.0-0.2-0.6-0.40.40.50.1-0.6-0.20.5
Intermittent access day 15 total locomotion0.00.00.2-0.0-0.3-0.2-0.0-0.1-0.2-0.4-0.1-0.10.00.4-0.1-0.30.2-0.10.0-0.10.10.2-0.1-0.30.3
Intermittent access total locomotion0.10.10.30.1-0.1-0.20.1-0.0-0.0-0.3-0.1-0.10.10.5-0.0-0.10.3-0.3-0.10.00.20.4-0.3-0.40.5
Intermittent access standard deviation2.72.94.4-2.01.71.92.01.91.81.1-1.9-1.92.1-1.31.81.6-1.5-2.1-2.01.81.9-1.4-1.70.30.4
Left kidney weight0.10.42.10.5-0.9-0.4-0.2-0.6-0.6-1.20.70.7-0.41.4-0.6-0.10.50.50.5-0.7-0.50.20.50.4-0.5
Right kidney weight0.71.85.3-0.2-1.6-0.4-0.5-1.0-1.0-2.01.41.4-1.02.2-1.20.8-0.30.81.1-1.5-1.5-0.91.82.1-2.3
Cocaine induced anxiety3.64.26.81.6-2.6-2.1-2.1-2.4-2.5-2.32.12.1-2.12.6-2.4-1.61.42.42.1-2.4-2.01.11.70.2-1.1
Post-drug Anxiety1.21.33.31.6-1.1-1.2-1.1-1.3-1.7-0.91.01.0-0.81.4-1.3-1.21.21.80.9-1.2-0.61.20.1-0.50.0
Baseline Anxiety2.82.95.3-0.52.11.51.71.81.62.2-1.9-1.92.0-2.11.90.6-0.6-1.5-1.92.02.20.0-2.3-1.01.6
Tail length1.02.94.2-1.71.92.02.02.02.02.0-1.9-1.91.9-1.51.91.9-1.6-1.6-1.81.81.7-1.3-1.30.60.2
Length with tail0.20.72.1-1.10.61.11.00.90.80.7-0.6-0.60.8-0.20.81.5-1.1-0.5-0.70.60.6-1.0-0.31.1-0.7
Length without tail1.22.64.41.2-2.0-1.5-1.5-1.7-1.8-1.92.02.0-1.72.1-1.8-0.81.01.81.7-1.8-1.70.81.50.4-1.0
Times rat made contact with spout2.22.53.8-0.61.71.31.71.71.71.8-1.9-1.91.8-1.91.80.5-0.4-1.5-1.92.01.9-0.0-2.0-1.01.6
Lifetime Intake1.01.23.0-0.21.00.61.11.00.90.5-1.2-1.21.3-0.51.0-0.00.0-1.3-1.31.21.60.3-1.7-1.21.7
Liver weight, left0.10.10.5-0.4-0.20.40.40.20.2-0.2-0.0-0.00.1-0.00.20.7-0.4-0.5-0.20.1-0.1-0.50.30.7-0.5
Liver weight, right0.20.30.7-0.70.20.60.50.50.40.4-0.7-0.70.5-0.50.50.5-0.8-0.7-0.60.40.5-0.5-0.40.3-0.2
Locomotor activity0.20.30.6-0.40.60.60.80.50.40.4-0.6-0.60.7-0.60.50.3-0.4-0.6-0.50.50.7-0.3-0.8-0.00.2
Locomotor testing distance0.81.32.2-1.51.01.41.41.21.10.9-1.1-1.11.1-1.21.11.4-1.4-1.4-0.91.00.9-1.3-0.60.9-0.5
Locomotor testing rearing0.81.23.3-1.70.71.31.31.01.10.6-0.8-0.80.8-1.10.81.8-1.7-0.9-0.60.60.4-1.70.11.5-1.1
Locomotion in novel chamber4.15.18.52.9-2.4-2.6-2.3-2.5-2.6-2.42.22.2-2.02.4-2.4-2.72.62.52.1-2.1-1.62.51.0-1.50.7
Locomotion in novel chamber post-restriction1.31.62.81.7-1.7-1.5-1.3-1.4-1.5-1.71.11.1-1.21.0-1.4-1.41.41.21.1-1.2-1.01.40.6-0.80.3
Fecal boli incidents, locomotor time 10.70.82.21.5-0.4-1.1-0.9-0.6-0.5-0.30.60.6-0.80.1-0.5-1.51.40.80.6-0.3-0.51.50.3-1.41.1
Change in fecal boli incidents, locomotor task0.40.41.4-1.20.30.60.60.60.70.2-0.6-0.60.5-0.20.51.0-0.9-0.8-0.50.40.2-1.1-0.00.5-0.2
Time >=10cm from walls, locomotor time 13.73.76.32.5-1.8-2.3-2.3-2.1-1.9-1.52.02.0-2.11.3-1.9-2.22.52.02.0-1.7-1.82.11.4-1.30.5
Bouts of movement, locomotor time 13.03.311.22.8-0.5-2.0-1.5-1.2-1.4-0.40.70.7-0.9-0.0-0.9-2.93.21.60.7-0.40.03.2-0.9-3.32.7
Total resting periods, locomotor time 13.03.39.82.7-0.8-2.1-1.7-1.4-1.6-0.61.01.0-1.10.2-1.2-2.93.11.81.0-0.7-0.33.1-0.5-3.12.3
Rest time, locomotor task time 11.41.63.70.01.20.60.91.11.01.2-1.5-1.51.3-1.51.2-0.40.4-0.9-1.41.51.60.7-1.8-1.61.9
Distance moved, locomotor task time 10.50.51.80.6-0.7-0.7-0.7-0.9-1.0-0.70.80.8-0.61.3-0.8-0.50.30.70.7-0.9-0.60.40.40.1-0.3
Vertical activity count, locomotor time 10.50.52.3-0.3-0.40.1-0.3-0.4-0.3-0.20.70.7-0.50.6-0.50.9-0.50.50.6-0.6-0.7-0.71.01.4-1.5
Time >=10cm from walls, locomotor time 20.10.10.20.30.40.10.10.20.30.5-0.2-0.20.1-0.40.3-0.20.4-0.3-0.20.30.20.4-0.1-0.30.3
Bouts of movement, locomotor time 20.91.02.81.4-0.8-1.1-1.0-0.9-1.1-0.90.60.6-0.60.5-0.9-1.71.40.90.7-0.7-0.21.6-0.2-1.20.9
Total resting periods, locomotor time 20.70.82.41.1-0.8-1.0-0.9-0.9-1.1-1.00.50.5-0.50.5-0.8-1.61.10.70.6-0.6-0.21.3-0.2-1.10.8
Rest time, locomotor task time 20.30.31.3-0.70.40.50.40.50.50.6-0.6-0.60.5-1.20.50.4-0.4-0.7-0.50.60.6-0.4-0.6-0.30.3
Distance moved, locomotor task time 20.80.92.71.6-0.7-1.1-0.9-1.0-1.1-0.70.90.9-0.80.9-0.9-1.21.31.00.8-0.8-0.61.40.2-0.90.4
Vertical activity count, locomotor time 20.70.71.41.1-0.8-0.7-0.9-0.9-0.8-0.71.01.0-0.90.7-0.9-0.40.71.21.0-0.9-1.00.70.90.3-0.7
Light reinforcement 12.44.37.92.1-2.4-2.3-2.1-2.3-2.4-2.52.22.2-2.12.8-2.3-2.02.02.12.1-2.2-1.91.71.5-0.70.2
Light reinforcement 20.50.62.01.0-1.1-0.8-0.6-0.8-0.9-1.10.70.7-0.51.4-0.7-0.90.90.60.6-0.7-0.31.00.1-0.50.4
Bone: marrow area0.10.20.4-0.30.30.40.50.50.60.3-0.6-0.60.4-0.50.50.3-0.5-0.6-0.60.50.4-0.2-0.3-0.00.2
Bone: maximum diameter0.10.20.6-0.40.30.60.60.50.40.4-0.4-0.40.5-0.30.40.8-0.7-0.6-0.40.40.3-0.4-0.20.5-0.3
Bone: maximum force0.20.30.70.1-0.5-0.2-0.3-0.4-0.3-0.50.50.5-0.50.6-0.40.5-0.10.40.5-0.6-0.7-0.30.90.8-0.8
Bone: maximum moment0.10.30.70.2-0.5-0.3-0.3-0.5-0.4-0.50.50.5-0.50.6-0.50.40.10.40.5-0.6-0.7-0.10.80.6-0.7
Mean time between licks in bursts1.72.44.41.4-1.9-1.7-1.7-1.8-1.7-1.91.51.5-1.72.1-1.7-1.41.21.41.5-1.7-1.60.91.4-0.3-0.2
Mean num. licks in bursts0.00.00.10.20.1-0.1-0.0-0.0-0.10.0-0.2-0.20.10.3-0.0-0.30.10.0-0.20.00.20.3-0.4-0.30.4
Cd content in liver0.10.20.6-0.6-0.00.30.10.10.2-0.1-0.3-0.3-0.00.10.10.6-0.7-0.40.0-0.1-0.2-0.80.40.8-0.7
Co content in liver0.30.30.6-0.50.50.60.60.60.60.6-0.7-0.70.6-0.50.60.5-0.8-0.4-0.60.50.5-0.5-0.40.2-0.0
Cu content in liver0.40.51.0-1.00.60.80.90.80.80.6-0.8-0.80.8-0.70.80.7-0.9-0.3-0.80.70.7-0.8-0.60.30.0
Fe content in liver2.42.96.3-2.51.52.11.81.71.81.4-1.5-1.51.4-1.51.52.3-2.5-1.7-1.41.31.0-2.4-0.41.8-1.3
K content in liver1.21.22.11.2-1.1-1.1-1.2-1.2-1.2-1.11.51.5-1.20.9-1.2-0.60.91.01.3-1.2-1.20.81.00.1-0.5
Mg content in liver0.40.40.90.5-0.7-0.5-0.6-0.7-0.6-0.70.90.9-0.70.5-0.70.00.30.60.8-0.7-0.80.20.80.5-0.7
Mn content in liver0.81.01.80.8-1.0-0.9-1.2-1.1-1.0-0.91.31.3-1.10.9-1.1-0.80.61.01.2-1.1-1.00.51.00.2-0.7
Na content in liver0.60.62.4-0.8-0.20.50.20.20.5-0.20.20.2-0.3-0.30.11.2-1.0-0.50.2-0.1-0.8-1.31.31.5-1.4
Rb content in liver1.62.03.81.8-1.2-1.6-1.5-1.4-1.6-1.21.41.4-1.11.1-1.3-1.92.01.81.2-1.2-0.71.80.3-1.20.6
Se content in liver0.00.00.20.4-0.2-0.2-0.2-0.2-0.2-0.20.20.2-0.10.3-0.2-0.20.20.20.1-0.2-0.10.40.0-0.10.1
Sr content in liver0.30.31.30.60.4-0.20.10.20.30.4-0.4-0.40.2-0.40.3-0.60.3-0.3-0.40.50.40.7-0.6-1.11.2
Zn content in liver0.00.00.2-0.1-0.3-0.2-0.1-0.2-0.3-0.4-0.0-0.0-0.10.4-0.2-0.0-0.20.20.1-0.2-0.1-0.10.0-0.00.0
Bone: minimum diameter0.20.40.70.7-0.8-0.6-0.7-0.7-0.7-0.80.70.7-0.70.8-0.7-0.20.40.50.7-0.8-0.80.40.80.2-0.4
Time in familiar zone, hab. session 12.01.93.5-0.31.51.21.41.41.31.5-1.6-1.61.7-1.61.60.4-0.5-1.2-1.71.71.80.2-1.9-0.91.3
Time in novel zone, hab. session 10.20.20.5-0.70.50.50.40.40.40.5-0.4-0.40.4-0.30.40.4-0.5-0.6-0.40.30.3-0.7-0.20.4-0.2
Total zone transitions, hab. session 11.31.83.6-0.1-1.6-0.8-1.1-1.2-1.2-1.51.41.4-1.41.6-1.40.1-0.21.01.5-1.6-1.7-0.71.91.5-1.9
Total locomotion distance, hab. session 11.01.42.31.2-1.5-1.3-1.3-1.4-1.4-1.41.21.2-1.21.5-1.3-1.00.91.31.3-1.3-1.20.81.0-0.2-0.2
Locomotion velocity, hab. session 11.31.83.11.0-1.7-1.3-1.4-1.5-1.5-1.71.41.4-1.51.7-1.5-0.80.81.41.5-1.6-1.50.51.40.2-0.6
Time in familiar zone, hab. session 20.40.40.6-0.80.60.70.80.70.60.6-0.7-0.70.8-0.70.70.6-0.5-0.6-0.80.70.7-0.6-0.70.10.2
Time in novel zone, hab. session 20.00.00.00.10.10.0-0.00.00.00.10.00.0-0.00.00.00.1-0.10.00.10.0-0.00.20.10.1-0.1
Total zone transitions, hab. session 20.10.20.40.6-0.7-0.4-0.4-0.4-0.4-0.60.30.3-0.30.6-0.4-0.60.40.30.3-0.3-0.20.50.2-0.20.0
Total locomotion distance, hab. session 20.81.12.71.6-0.9-1.2-0.9-0.9-1.0-0.90.50.5-0.60.8-0.8-1.61.51.20.6-0.6-0.21.7-0.2-1.51.2
Locomotion velocity, hab. session 20.91.12.51.5-1.1-1.3-1.1-1.0-1.1-1.10.80.8-0.81.1-1.0-1.61.41.20.8-0.8-0.51.40.1-1.20.8
Novel to familiar place preference ratio1.61.73.00.11.50.81.21.31.31.6-1.4-1.41.4-1.61.40.00.4-1.0-1.41.61.60.6-1.7-1.41.7
Novelty place preference1.71.72.90.11.60.91.21.31.31.6-1.4-1.41.4-1.71.40.10.3-1.0-1.51.61.60.5-1.7-1.31.6
Time in novel zone, NPP test2.22.33.7-0.11.81.11.41.51.51.9-1.6-1.61.7-1.91.70.30.1-1.3-1.71.91.90.4-1.9-1.31.7
Total zone transitions, NPP test0.71.01.80.9-1.3-1.1-1.1-1.1-1.2-1.20.90.9-1.01.3-1.1-0.90.71.11.1-1.1-1.00.60.8-0.1-0.3
Total locomotion distance, NPP test0.81.11.81.3-1.1-1.3-1.1-1.1-1.2-1.00.80.8-0.91.1-1.0-1.21.21.21.0-0.9-0.71.30.3-0.90.6
Locomotion velocity, NPP test1.52.13.01.6-1.7-1.7-1.6-1.6-1.7-1.61.41.4-1.51.6-1.6-1.51.41.71.5-1.5-1.31.40.9-0.70.2
Intraocular pressure0.91.32.51.6-1.1-1.4-1.2-1.1-1.2-1.21.01.0-0.91.0-1.1-1.61.41.21.0-0.9-0.71.40.3-1.20.7
Delta distance traveled before/after self-admin0.30.41.5-0.6-0.40.1-0.1-0.3-0.4-0.40.40.4-0.30.8-0.50.8-0.70.20.4-0.7-0.5-0.60.61.2-1.2
Delta ambulatory time before/after self-admin0.30.31.0-0.5-0.30.0-0.1-0.3-0.5-0.50.30.3-0.31.0-0.50.5-0.60.20.3-0.6-0.4-0.50.51.0-1.0
Parametrial fat weight0.00.00.10.1-0.00.10.20.10.2-0.0-0.2-0.20.1-0.10.10.1-0.0-0.1-0.20.10.00.20.00.1-0.2
Pavlov. Cond. lever latency0.30.41.80.8-0.0-0.6-0.4-0.3-0.4-0.00.00.0-0.10.0-0.2-1.10.90.20.10.00.20.8-0.6-1.31.3
Pavlov. Cond. magazine entry latency0.00.00.2-0.40.20.30.20.20.20.2-0.1-0.10.2-0.30.20.2-0.20.1-0.10.10.2-0.1-0.10.3-0.3
Pavlov. Cond. change in total contacts0.10.10.10.30.20.00.10.20.30.3-0.1-0.10.1-0.40.2-0.10.40.1-0.20.30.10.4-0.1-0.30.4
Pavlov. Cond. index score0.30.40.7-0.70.70.80.80.70.80.7-0.5-0.50.6-0.70.70.8-0.6-0.4-0.60.60.5-0.4-0.30.5-0.3
Pavlov. Cond. latency score0.30.41.0-0.80.60.90.80.70.80.6-0.5-0.50.6-0.60.71.0-0.8-0.5-0.60.60.4-0.6-0.10.7-0.5
Pavlov. Cond. lever contacts0.20.20.9-0.60.10.50.30.30.40.1-0.1-0.10.1-0.10.20.8-0.6-0.1-0.10.1-0.2-0.50.40.9-0.9
Pavlov. Cond. magazine entry number0.70.91.41.0-1.1-1.2-1.1-1.1-1.0-1.10.90.9-1.11.2-1.0-0.80.80.71.0-1.0-1.00.50.9-0.40.1
Pavlov. Cond. intertrial magazine entries0.20.31.21.00.1-0.3-0.0-0.1-0.00.1-0.2-0.20.1-0.10.1-0.40.90.1-0.20.20.21.0-0.5-1.01.1
Pavlov. Cond. lever-magazine prob. diff.0.10.20.3-0.30.50.50.50.50.50.5-0.4-0.40.5-0.60.50.5-0.2-0.2-0.50.50.40.0-0.30.2-0.1
Pavlov. Cond. response bias0.20.20.4-0.40.50.60.50.50.50.5-0.3-0.30.4-0.60.50.6-0.3-0.2-0.30.40.3-0.2-0.20.4-0.3
Pavlov. Cond. lever latency0.10.10.70.9-0.2-0.4-0.3-0.2-0.2-0.20.30.3-0.30.1-0.2-0.50.70.30.3-0.1-0.20.70.1-0.50.4
Pavlov. Cond. magazine entry latency0.70.82.9-1.0-0.7-0.2-0.5-0.6-0.7-0.80.80.8-0.81.0-0.80.5-0.80.60.9-1.0-1.0-1.11.21.5-1.7
Pavlov. Cond. change in total contacts0.30.40.9-1.00.60.70.70.70.80.7-0.7-0.70.6-0.60.70.8-0.8-0.7-0.70.60.4-0.8-0.30.3-0.0
Pavlov. Cond. index score0.20.21.2-1.10.00.40.30.20.1-0.0-0.2-0.20.20.10.10.6-0.9-0.3-0.1-0.10.0-0.90.10.8-0.7
Pavlov. Cond. latency score0.10.10.8-0.9-0.10.20.1-0.0-0.1-0.2-0.1-0.10.00.2-0.10.4-0.7-0.10.0-0.2-0.1-0.80.20.7-0.6
Pavlov. Cond. lever contacts0.30.41.7-1.30.50.70.60.50.50.4-0.6-0.60.5-0.40.40.8-1.1-0.7-0.50.30.3-1.0-0.10.7-0.5
Pavlov. Cond. magazine entry number0.40.41.71.30.2-0.3-0.00.00.10.3-0.1-0.10.1-0.30.2-0.71.10.0-0.20.40.31.3-0.6-1.31.3
Pavlov. Cond. intertrial magazine entries1.72.25.52.3-1.2-1.8-1.4-1.4-1.5-1.21.21.2-1.11.0-1.2-2.12.21.51.0-1.0-0.62.30.0-1.81.3
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.9-0.20.20.1-0.0-0.1-0.20.00.0-0.10.2-0.10.5-0.7-0.10.1-0.3-0.2-0.80.30.8-0.8
Pavlov. Cond. response bias0.50.62.5-1.5-0.10.50.20.10.1-0.20.00.0-0.10.2-0.11.1-1.3-0.30.1-0.3-0.4-1.50.71.6-1.5
Time in closed arm before self-admin1.82.13.8-0.61.71.21.41.51.51.7-1.6-1.61.7-2.01.60.4-0.6-1.3-1.61.81.80.0-1.8-0.81.3
Time in closed arm after self-admin0.50.50.9-0.90.70.90.90.70.60.6-0.8-0.80.9-0.30.60.7-0.9-0.9-0.80.60.8-0.6-0.70.5-0.1
Time in open arm before self-admin0.80.92.30.9-1.0-1.0-0.9-1.0-1.1-1.30.80.8-0.81.5-1.0-1.10.90.90.8-1.0-0.70.80.4-0.40.1
Time in open arm after self-admin0.20.20.5-0.50.10.50.40.40.70.2-0.2-0.20.1-0.50.40.7-0.5-0.4-0.20.3-0.1-0.70.40.6-0.4
Bone: periosteal estimation0.10.20.6-0.30.30.50.50.40.40.3-0.4-0.40.4-0.20.40.7-0.6-0.6-0.40.30.2-0.4-0.10.5-0.3
Bone: periosteal perimeter0.20.30.5-0.00.50.50.60.50.40.5-0.6-0.60.7-0.50.50.4-0.2-0.5-0.60.50.70.1-0.7-0.10.3
Bone: post-yield work0.40.51.9-0.5-0.70.0-0.2-0.3-0.3-0.70.60.6-0.50.5-0.50.8-0.40.50.5-0.7-0.8-0.81.01.3-1.4
Progressive ratio test 1 active lever presses0.40.41.40.9-0.0-0.40.0-0.1-0.3-0.7-0.1-0.10.20.8-0.1-0.80.9-0.1-0.20.10.41.1-0.7-1.11.2
Progressive ratio test 1 breakpoint0.30.31.50.80.1-0.30.2-0.0-0.2-0.5-0.2-0.20.30.70.0-0.70.8-0.2-0.30.20.61.0-0.8-1.11.2
Progressive ratio test 1 inactive lever presses0.40.51.6-1.10.10.60.60.30.2-0.4-0.5-0.50.40.80.10.9-1.2-0.7-0.4-0.00.2-1.30.01.1-0.7
Progressive ratio test 2 active lever presses0.00.00.20.20.1-0.10.1-0.0-0.1-0.40.10.10.00.4-0.10.30.2-0.10.1-0.1-0.00.1-0.0-0.10.2
Progressive ratio test 2 breakpoint0.10.10.60.4-0.2-0.5-0.2-0.4-0.4-0.60.20.2-0.30.8-0.4-0.10.40.20.3-0.3-0.20.40.1-0.40.3
Progressive ratio test 2 inactive lever presses0.30.31.1-0.8-0.20.40.40.1-0.0-0.7-0.1-0.10.20.7-0.10.8-0.8-0.3-0.0-0.2-0.0-1.00.21.1-0.7
Incentive Sensitization - Responses0.40.41.2-0.1-0.5-0.3-0.4-0.5-0.3-0.40.60.6-0.70.4-0.50.7-0.20.30.7-0.6-0.9-0.61.10.8-0.9
Incentive Sensitization - Breakpoint0.60.61.7-0.1-0.7-0.5-0.6-0.7-0.5-0.60.80.8-0.90.6-0.70.5-0.10.50.9-0.9-1.1-0.61.30.8-1.1
Sum of active levers in priming session hrs 5-62.52.44.3-0.21.81.21.51.61.51.8-1.9-1.91.8-1.21.70.1-0.3-1.6-1.91.82.00.3-2.1-1.11.8
Progressive ratio0.80.93.91.7-0.1-0.9-0.6-0.4-0.40.00.20.2-0.2-0.4-0.2-1.41.50.60.10.10.21.9-0.7-2.01.6
Food seeking constrained by brief footshock0.20.20.60.20.1-0.5-0.5-0.5-0.7-0.10.30.3-0.30.6-0.5-0.60.50.70.4-0.50.00.5-0.2-0.30.0
Seeking ratio, punishment vs. effort0.30.41.9-1.20.30.60.30.1-0.00.0-0.1-0.10.20.6-0.00.8-1.0-0.3-0.1-0.2-0.0-1.20.31.4-1.2
Retroperitoneal fat weight0.41.23.50.7-1.5-0.9-0.8-1.1-1.0-1.61.11.1-1.11.9-1.1-0.20.51.10.8-1.2-1.30.31.30.5-0.8
Reaction time number correct0.91.32.11.1-1.1-1.5-1.4-1.3-1.3-1.11.21.2-1.41.0-1.3-1.01.11.41.2-1.1-1.20.91.0-0.70.2
Reaction time mean minus median0.91.21.8-1.31.21.21.31.21.21.1-1.2-1.21.2-1.11.21.0-1.1-1.3-1.21.11.0-0.9-0.80.30.1
Reaction time mean minus median AUC0.60.81.4-1.21.01.01.01.01.00.9-0.9-0.90.9-0.70.90.9-1.0-0.9-0.90.90.8-0.9-0.60.40.0
Reaction time num false alarms1.52.13.41.7-1.6-1.6-1.6-1.6-1.7-1.51.41.4-1.31.3-1.6-1.81.61.51.4-1.4-1.01.60.6-0.80.3
Reaction time num false alarms AUC2.23.04.12.0-2.0-2.0-1.9-1.9-2.0-1.81.91.9-1.71.6-1.9-2.01.81.81.8-1.7-1.51.81.0-0.80.2
Reaction time trials correct on left0.91.32.11.1-1.1-1.5-1.4-1.3-1.3-1.11.21.2-1.41.0-1.3-1.01.11.41.2-1.1-1.20.91.0-0.70.2
Reaction time trials on left0.91.22.01.0-1.0-1.4-1.4-1.3-1.2-1.01.21.2-1.30.9-1.2-1.01.01.31.1-1.1-1.10.90.9-0.70.2
Reaction time mean2.43.34.5-1.92.12.02.02.02.02.0-2.1-2.12.0-1.92.01.6-1.9-2.1-2.01.91.8-1.3-1.50.40.2
Reaction time mean AUC2.02.73.9-1.52.01.81.71.81.81.9-1.9-1.91.8-1.71.81.3-1.6-1.8-1.81.71.7-1.0-1.50.20.3
Median of all reaction times2.43.34.6-1.72.22.01.92.02.02.1-2.1-2.12.0-1.92.01.5-1.8-2.0-1.91.91.9-1.1-1.60.30.2
Reaction time omissions0.60.81.2-1.11.01.01.11.01.10.8-0.9-0.90.9-0.51.01.1-1.1-1.0-0.80.80.6-1.0-0.30.5-0.0
Reaction time false alarm rate0.81.11.71.2-1.3-1.1-1.0-1.1-1.2-1.21.11.1-0.91.0-1.1-1.31.11.01.1-1.1-0.81.10.5-0.3-0.0
Reaction time premature initiation rate0.00.10.2-0.4-0.00.40.30.20.10.2-0.1-0.10.3-0.10.10.3-0.3-0.1-0.10.00.2-0.3-0.20.5-0.4
Reaction time premature initiations0.10.10.20.1-0.4-0.3-0.4-0.4-0.5-0.20.50.5-0.40.3-0.4-0.10.20.50.4-0.4-0.30.20.30.1-0.3
Std. dev. reaction times1.31.82.8-1.71.41.51.41.41.51.4-1.4-1.41.3-1.41.41.3-1.6-1.7-1.31.31.1-1.3-0.80.6-0.1
Reaction time trials completed0.91.22.01.0-1.0-1.4-1.4-1.3-1.2-1.01.21.2-1.30.9-1.2-1.01.01.31.1-1.1-1.10.90.9-0.70.2
Reaction time trials AUC0.81.11.81.0-1.0-1.4-1.3-1.2-1.1-1.01.11.1-1.30.9-1.2-1.01.01.31.1-1.0-1.10.80.9-0.70.2
Run reversals in cocaine runway, females1.41.32.61.0-1.6-1.1-1.3-1.3-1.4-1.21.51.5-1.20.6-1.3-1.00.81.41.4-1.3-1.10.70.80.0-0.6
Run reversals in cocaine runway, males0.20.20.80.5-0.1-0.0-0.0-0.2-0.6-0.1-0.2-0.20.40.8-0.2-0.60.10.1-0.3-0.20.60.6-0.9-0.30.4
Latency to leave start box in cocaine runway2.42.63.91.4-2.0-1.5-1.7-1.8-1.8-1.91.81.8-1.81.7-1.9-0.90.81.71.9-1.9-1.80.81.70.4-1.1
Latency to leave start box in cocaine runway, F1.61.73.80.1-1.5-0.8-1.3-1.3-1.3-1.41.41.4-1.41.2-1.40.1-0.21.11.6-1.6-1.6-0.41.71.4-1.9
Latency to leave start box in cocaine runway, M2.62.56.52.6-1.6-1.8-1.6-1.6-1.7-1.71.51.5-1.31.3-1.5-1.91.91.61.3-1.3-1.02.10.5-1.30.8
Std. dev. time between licks in bursts0.30.31.01.0-0.5-0.8-0.6-0.5-0.4-0.40.30.3-0.50.3-0.4-0.80.90.30.3-0.3-0.40.80.2-0.90.8
Total sessions with >9 infusions0.60.61.81.2-0.3-0.9-0.5-0.6-0.7-1.10.20.2-0.30.9-0.5-1.11.10.30.2-0.30.01.2-0.4-1.31.2
Short access day 1 total inactive lever presses0.50.51.7-0.4-1.1-0.2-0.3-0.5-0.7-1.30.60.6-0.51.2-0.80.2-0.40.20.5-0.9-0.6-0.80.71.1-1.1
Short access day 10 total inactive lever presses0.50.62.4-1.3-0.50.60.10.0-0.2-0.20.10.10.10.3-0.11.0-1.20.10.1-0.4-0.2-1.50.41.6-1.5
Short access day 1 total infusions0.20.21.70.3-0.7-0.4-0.3-0.4-0.6-1.30.20.2-0.21.0-0.5-0.60.3-0.10.1-0.5-0.10.2-0.0-0.20.3
Short access day 10 total infusions2.32.67.70.21.60.71.31.31.01.0-1.8-1.81.9-0.91.5-0.50.5-1.4-1.91.82.41.1-2.8-2.22.8
Short access total infusions0.40.52.30.50.40.00.40.40.2-0.2-0.6-0.60.7-0.10.4-0.50.5-0.7-0.70.61.00.7-1.2-1.21.5
Short access day 1 locomotion0.10.20.50.6-0.4-0.4-0.3-0.2-0.3-0.60.00.0-0.10.4-0.2-0.70.50.00.1-0.10.10.6-0.2-0.60.6
Short access day 10 total locomotion0.20.20.4-0.40.60.50.60.50.50.2-0.5-0.50.60.10.50.5-0.2-0.6-0.50.50.6-0.1-0.50.10.3
Short access total locomotion0.20.20.50.7-0.4-0.6-0.4-0.5-0.5-0.70.50.5-0.50.7-0.5-0.30.60.30.5-0.4-0.40.60.3-0.30.2
One hour access (0.3 mA shock)4.55.28.7-1.22.51.92.42.52.42.1-2.7-2.72.8-2.22.60.9-0.7-2.7-2.72.82.9-0.2-3.0-1.42.4
Compulsive drug intake0.10.10.7-0.10.30.30.10.30.30.5-0.1-0.10.1-0.80.30.3-0.2-0.3-0.10.30.1-0.2-0.00.0-0.0
One hour access (shock baseline)2.63.06.0-0.91.81.51.91.91.71.5-2.1-2.12.2-1.21.90.6-0.5-1.9-2.12.12.4-0.2-2.4-1.11.9
Social response proportion0.40.51.1-0.80.50.80.80.80.70.4-0.6-0.60.9-0.80.70.2-0.6-0.7-1.00.80.9-0.5-0.80.10.1
Social responses1.31.72.7-1.41.31.51.61.51.41.3-1.4-1.41.6-1.01.41.0-1.3-1.3-1.71.41.5-1.0-1.30.30.3
Social time3.95.29.0-3.02.12.82.82.52.42.0-2.2-2.22.4-2.12.32.7-2.6-2.1-2.32.12.0-2.5-1.41.5-0.5
Soleus weight1.64.76.22.2-2.4-2.4-2.4-2.4-2.2-2.52.52.5-2.42.4-2.3-1.92.22.22.4-2.2-2.31.62.0-0.5-0.3
Bone: stiffness0.61.02.4-0.1-1.3-0.5-0.8-0.9-0.8-1.21.01.0-1.11.0-1.00.2-0.10.91.0-1.1-1.4-0.61.61.2-1.4
Tibialis anterior weight3.612.116.03.7-3.6-4.0-4.0-3.9-3.9-3.63.83.8-3.73.6-3.8-3.63.73.83.8-3.5-3.23.12.4-1.40.2
Time to tail flick, vehicle, before self-admin0.20.20.5-0.10.60.40.40.50.60.5-0.4-0.40.3-0.70.50.3-0.2-0.2-0.40.50.3-0.1-0.2-0.10.3
Time to tail flick, vehicle, after self-admin0.20.20.60.10.50.40.40.50.60.5-0.5-0.50.5-0.80.60.40.0-0.1-0.50.70.50.1-0.4-0.30.5
Time to tail flick, test, before self-admin1.71.64.41.8-1.0-1.6-1.4-1.3-1.4-1.01.01.0-1.10.6-1.2-2.11.71.21.0-0.9-0.61.80.1-1.61.0
Time to tail flick, test, after self-admin0.60.61.91.4-0.7-0.9-0.7-0.6-0.5-0.70.40.4-0.6-0.0-0.5-1.41.20.60.4-0.3-0.41.30.1-1.10.9
Delta time to tail flick, vehicle, before/after SA0.00.00.10.2-0.3-0.2-0.2-0.2-0.2-0.20.20.2-0.20.1-0.2-0.10.30.40.2-0.1-0.20.20.1-0.20.1
Delta time to tail flick, test, before/after SA1.00.91.8-0.81.01.11.11.21.30.9-1.1-1.11.0-1.21.20.9-0.8-1.1-1.11.10.8-0.7-0.60.20.3
Tibia length0.20.62.6-0.80.40.90.80.60.80.4-0.2-0.20.3-0.50.61.6-1.1-0.7-0.40.3-0.1-1.10.51.4-1.1
Ambulatory time before self-admin0.10.10.4-0.20.20.40.30.40.60.3-0.4-0.40.2-0.50.40.1-0.4-0.6-0.40.40.1-0.40.10.3-0.0
Ambulatory time after self-admin0.50.62.7-0.8-0.40.3-0.0-0.1-0.1-0.60.20.2-0.31.1-0.30.7-1.1-0.30.2-0.6-0.6-1.11.01.6-1.5
Bone: tissue strength0.30.30.60.5-0.5-0.6-0.5-0.6-0.5-0.50.60.6-0.60.6-0.6-0.30.60.80.6-0.6-0.60.40.6-0.1-0.0
Total heroin consumption1.92.24.4-0.41.91.31.61.61.31.6-1.8-1.81.9-1.01.60.6-0.6-1.4-1.71.72.00.2-2.1-0.81.5
Bone: trabecular number2.43.89.1-2.81.72.42.11.91.91.7-1.6-1.61.6-1.51.73.0-2.6-1.8-1.51.41.0-2.6-0.42.3-1.6
Bone: trabecular spacing2.02.64.12.0-1.8-1.9-1.8-1.7-1.7-1.81.61.6-1.61.7-1.6-2.01.81.81.5-1.5-1.31.61.0-0.90.4
Bone: trabecular thickness4.14.97.8-2.72.52.62.52.42.42.4-2.2-2.22.1-2.22.32.8-2.6-2.3-2.12.01.7-2.3-1.11.5-0.7
Bone: trabecular tissue density0.30.51.0-0.2-0.8-0.4-0.7-0.7-0.6-0.80.70.7-0.80.6-0.8-0.1-0.20.60.7-0.9-0.9-0.51.00.8-1.0
Water consumed over 24 hours0.10.10.30.20.0-0.00.10.10.10.1-0.2-0.20.2-0.20.1-0.40.20.1-0.30.20.30.3-0.4-0.50.5
Number of responses in last shaping day0.20.20.9-0.80.30.50.60.40.20.1-0.2-0.20.4-0.00.20.9-0.9-0.3-0.20.10.3-0.8-0.20.6-0.2