Hub : Genes

Mrps24

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	LHb	gene expression	Mrps24	0.2	0.13	4.8e-04	0.09	0.08	0.09	0.06	3.9e-03	6.2e-03	4.7e-03	1.7e-02
2	Adipose	gene expression	Mrps24	0.02	0.02	7.6e-03	0.02	0.01	0	0.02	1.4e-03	2.0e-02	1.0e-01	4.3e-03
3	Liver	intron excision ratio	chr14_80585233_80588417	0.04	0.03	5.4e-05	0.03	0.03	0.02	0.02	7.3e-04	8.4e-04	4.4e-03	1.7e-03
4	Liver	intron excision ratio	chr14_80588528_80588606	0.05	0.03	1.4e-06	0.05	0.04	0.03	0.04	5.8e-06	2.5e-05	1.6e-04	5.4e-05
5	Brain	gene expression	Mrps24	0.04	0.03	1.2e-05	0.04	0.06	0.05	0.04	9.7e-05	6.4e-06	3.8e-05	9.4e-05
6	pVTA	intron excision ratio	chr14_80585233_80588606	0.1	0.07	2.3e-05	0.1	0.11	0.11	0.1	5.5e-05	1.7e-05	2.2e-05	5.6e-05
7	Liver	gene expression	Mrps24	0.08	0.04	4.9e-13	0.09	0.11	0.1	0.1	3.2e-10	8.0e-12	2.1e-11	3.9e-11
8	pVTA	intron excision ratio	chr14_80585233_80588417	0.06	0.05	1.9e-03	0.04	0.06	0.02	0.04	6.6e-03	9.8e-04	4.0e-02	7.1e-03
9	PL	intron excision ratio	chr14_80585233_80588606	0.08	0.05	5.5e-09	0.08	0.08	0.08	0.08	4.7e-09	8.4e-09	8.3e-09	9.6e-09
10	Brain	intron excision ratio	chr14_80588528_80588606	0.06	0.04	5.3e-06	0.05	0.06	0.06	0.05	3.4e-05	5.6e-06	6.9e-06	2.8e-05
11	Brain	intron excision ratio	chr14_80585233_80588606	0.17	0.12	6.0e-09	0.1	0.09	0.09	0.1	1.2e-09	4.8e-09	2.4e-08	9.1e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.1	0.1	0.3	-0.6	-0.4	-0.4	0.4	0.2	0.2	0.2	-0.2	-0.1	-0.2	0.1
Area under the delay curve	3.5	3.7	4.7	2.1	1.8	1.8	-1.8	-1.9	-1.9	-2.1	2.2	1.7	2.0	-1.8
BMI with tail	0.0	0.0	0.1	-0.0	-0.3	-0.2	0.2	-0.1	-0.1	-0.1	0.2	-0.0	0.2	0.0
BMI without tail	0.0	0.1	0.3	-0.3	-0.5	-0.6	0.6	0.1	0.1	0.1	-0.1	-0.2	0.0	0.1
Body weight	1.3	5.3	6.8	2.3	2.2	2.0	-2.0	-2.4	-2.4	-2.5	2.6	2.3	2.5	-2.2
Weight adjusted by age	0.4	0.4	0.8	0.9	0.7	0.7	-0.7	-0.6	-0.6	-0.7	0.7	0.6	0.6	-0.5
Bone surface	0.2	0.4	0.7	0.4	0.7	0.8	-0.8	-0.6	-0.7	-0.6	0.6	0.7	0.5	-0.7
Bone volume	0.2	0.4	0.6	0.3	0.6	0.7	-0.7	-0.6	-0.6	-0.6	0.6	0.8	0.6	-0.8
Breakpoint value in progressive ratio session	1.4	1.5	2.4	1.5	1.1	1.2	-1.2	-1.2	-1.2	-1.2	1.2	1.1	1.2	-1.1
Number of licking bursts	3.1	3.6	4.0	1.9	2.0	1.9	-1.9	-1.9	-1.9	-1.9	1.9	1.8	1.9	-1.9
Context. condit. distance diff. score	3.8	4.6	5.3	-2.3	-2.2	-2.3	2.3	2.1	2.1	2.2	-2.2	-1.8	-2.1	1.9
Locomotion velocity, session 1	0.1	0.1	0.1	0.3	0.4	0.3	-0.3	0.0	0.0	0.1	-0.2	0.2	-0.2	-0.3
Locomotion distance, session 1	0.5	0.6	1.2	-1.1	-0.8	-0.9	0.9	0.8	0.8	0.6	-0.4	-0.7	-0.7	0.6
Locomotion velocity, session 2	0.1	0.1	0.3	0.1	0.3	0.5	-0.5	-0.1	-0.2	0.1	-0.2	0.5	-0.1	-0.4
Locomotion distance, session 2	0.9	1.3	2.8	-1.7	-1.1	-1.1	1.1	1.2	1.1	1.1	-1.0	-0.9	-1.1	0.8
Locomotion velocity, session 3	2.1	2.5	4.2	-2.1	-1.7	-1.5	1.5	1.6	1.6	1.5	-1.5	-1.4	-1.5	1.3
Locomotion distance, session 3	0.4	0.4	0.9	-0.2	0.3	0.6	-0.6	-0.6	-0.6	-0.6	0.6	0.9	0.6	-0.9
Stereotopy head waving bouts, day 3	0.8	0.9	1.5	-1.2	-1.0	-1.0	1.0	0.9	0.9	0.9	-0.8	-1.0	-0.8	1.0
Stereotopy head waving duration, day 3	2.1	2.6	3.0	-1.4	-1.6	-1.6	1.6	1.6	1.6	1.6	-1.6	-1.7	-1.6	1.6
Locomotion velocity, session 7	0.3	0.3	0.4	0.4	0.6	0.6	-0.6	-0.5	-0.5	-0.5	0.5	0.6	0.5	-0.6
Locomotion distance, session 7	0.1	0.1	0.4	-0.7	-0.2	-0.3	0.3	0.4	0.4	0.4	-0.5	-0.2	-0.4	0.2
Stereotopy head waving bouts, day 7	0.7	0.7	1.0	-0.6	-0.8	-0.8	0.8	0.9	0.9	1.0	-1.0	-0.9	-1.0	0.8
Stereotopy head waving duration, day 7	0.1	0.1	0.1	-0.2	-0.2	-0.2	0.2	0.3	0.2	0.2	-0.2	-0.3	-0.3	0.2
Locomotion velocity, session 8	1.0	1.2	2.0	-1.3	-1.0	-0.8	0.8	1.2	1.1	1.3	-1.4	-0.7	-1.3	0.8
Locomotion distance, session 8	7.3	10.7	13.2	-3.6	-3.3	-3.4	3.4	3.3	3.3	3.3	-3.3	-2.8	-3.2	2.7
Degree of sensitization distance	2.5	2.5	3.2	-1.2	-1.2	-1.5	1.5	1.6	1.6	1.7	-1.8	-1.6	-1.7	1.7
Degree of sensitization stereotypy	0.0	0.0	0.2	0.4	0.0	0.0	-0.0	-0.1	-0.1	-0.1	0.0	0.1	0.1	-0.2
Conditioned locomotion	1.0	1.2	2.0	-1.4	-1.3	-1.2	1.2	1.0	1.1	0.8	-0.6	-1.1	-0.8	1.1
Cocaine response after cond. corrected	1.4	1.6	2.4	1.6	1.4	1.3	-1.3	-1.3	-1.2	-1.2	1.2	1.0	1.2	-1.1
Cocaine response after cond. not corrected	1.5	1.7	2.5	1.6	1.4	1.2	-1.2	-1.3	-1.3	-1.3	1.3	1.0	1.3	-1.2
Cocaine response before conditioning	0.4	0.5	0.6	-0.7	-0.8	-0.8	0.8	0.7	0.7	0.6	-0.6	-0.7	-0.6	0.6
Saline control response	0.4	0.6	1.2	-1.1	-0.9	-0.7	0.7	0.7	0.7	0.8	-0.8	-0.6	-0.7	0.6
Bone: connectivity density	0.2	0.3	0.6	-0.8	-0.5	-0.5	0.5	0.5	0.5	0.5	-0.5	-0.4	-0.5	0.4
Bone: cortical apparent density	0.7	1.0	1.3	1.0	1.1	0.9	-0.9	-1.0	-1.0	-0.9	0.9	1.0	1.0	-1.1
Bone: cortical area	3.0	4.6	5.1	2.2	2.3	2.1	-2.1	-2.1	-2.1	-2.2	2.2	2.1	2.1	-2.1
Bone: cortical porosity	0.0	0.0	0.1	0.2	0.0	-0.0	0.0	-0.2	-0.1	-0.2	0.2	0.1	0.2	-0.1
Bone: cortical porosity	0.2	0.2	0.3	-0.3	-0.5	-0.6	0.6	0.4	0.4	0.4	-0.3	-0.5	-0.4	0.4
Bone: cortical thickness	1.9	3.1	3.8	1.6	1.8	1.8	-1.8	-1.8	-1.8	-1.9	2.0	1.7	1.8	-1.7
Bone: cortical thickness	0.5	0.6	0.9	-1.0	-0.7	-0.8	0.8	0.7	0.7	0.6	-0.5	-0.8	-0.7	0.8
Bone: cortical tissue density	0.8	1.0	1.4	1.1	1.2	0.9	-0.9	-1.0	-1.0	-1.0	0.9	1.0	1.0	-1.1
Condit. Reinf. active minus inactive responses	1.2	1.3	1.9	0.9	1.1	1.0	-1.0	-1.2	-1.2	-1.1	1.1	1.4	1.2	-1.3
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	0.2	0.3	0.1	-0.1	-0.2	-0.2	-0.0	-0.2	0.4	0.1	-0.3
Condit. Reinf. active responses	0.7	0.8	1.3	0.5	0.9	0.8	-0.8	-0.9	-0.9	-0.9	0.8	1.1	0.9	-1.1
Condit. Reinf. inactive responses	0.3	0.4	0.6	0.1	0.5	0.6	-0.6	-0.6	-0.6	-0.7	0.8	0.8	0.7	-0.8
Incentive salience index mean	1.6	2.0	2.5	1.0	1.3	1.3	-1.3	-1.5	-1.5	-1.5	1.5	1.6	1.6	-1.5
Condit. Reinf. lever presses	0.5	0.6	1.2	0.3	0.6	0.7	-0.7	-0.8	-0.8	-1.0	1.1	0.8	0.9	-0.7
Condit. Reinf. active minus inactive responses	0.4	0.5	0.7	-0.8	-0.7	-0.6	0.6	0.7	0.7	0.7	-0.7	-0.8	-0.7	0.8
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.0	-0.1	0.0	0.0	-0.0	-0.0	0.0	-0.1	0.1	-0.2	0.1	0.2
Condit. Reinf. active responses	0.6	0.8	1.1	-0.9	-0.9	-0.8	0.8	0.9	0.9	0.9	-0.8	-1.0	-0.9	1.0
Condit. Reinf. inactive responses	0.9	1.1	1.4	-0.9	-1.0	-1.0	1.0	1.0	1.0	1.1	-1.2	-1.0	-1.1	1.0
Condit. Reinf. lever presses	0.4	0.6	0.9	-1.0	-0.8	-0.7	0.7	0.7	0.7	0.7	-0.7	-0.8	-0.7	0.8
Condit. Reinf. lever reinforcers received	0.4	0.6	0.9	-0.9	-0.8	-0.7	0.7	0.8	0.8	0.7	-0.7	-0.9	-0.8	0.9
Conditioned reinforcement - actives	0.0	0.0	0.0	0.1	-0.0	-0.1	0.1	0.0	-0.0	0.0	0.0	-0.0	0.0	0.0
Conditioned reinforcement - inactives	0.1	0.1	0.1	0.4	0.3	0.2	-0.2	-0.2	-0.2	-0.2	0.2	0.3	0.2	-0.3
Conditioned locomotion	0.0	0.0	0.1	0.2	-0.1	-0.1	0.1	-0.2	-0.1	-0.2	0.3	0.1	0.2	-0.1
Patch foraging indifference point 0 sec	1.8	2.9	4.3	1.7	1.6	1.5	-1.5	-1.7	-1.7	-1.6	1.4	2.0	1.7	-2.1
Patch foraging indifference point AUC	0.1	0.1	0.2	0.3	0.4	0.4	-0.4	-0.4	-0.4	-0.3	0.2	0.5	0.3	-0.5
Delay disc. indifference point, 0s delay	0.8	0.9	1.4	1.2	1.0	1.0	-1.0	-0.9	-0.9	-0.9	0.9	0.8	0.9	-0.8
Delay disc. indifference point, 16s delay	2.9	2.9	3.9	2.0	1.6	1.6	-1.6	-1.7	-1.7	-1.8	1.8	1.6	1.7	-1.7
Delay disc. indifference point, 2s delay	1.1	1.2	2.0	1.1	1.0	1.0	-1.0	-1.1	-1.1	-1.3	1.4	1.1	1.2	-1.1
Delay disc. indifference point, 24s delay	1.8	1.8	2.0	1.2	1.3	1.3	-1.3	-1.3	-1.3	-1.4	1.4	1.4	1.4	-1.4
Delay disc. indifference point, 4s delay	3.1	3.2	4.4	1.9	1.7	1.7	-1.7	-1.8	-1.8	-2.0	2.1	1.6	1.9	-1.6
Delay disc. indifference point, 8s delay	1.1	1.2	1.7	1.2	1.0	1.0	-1.0	-1.1	-1.1	-1.2	1.3	0.8	1.1	-0.9
Indifference point function ln k	0.0	0.0	0.1	-0.3	-0.1	-0.0	0.0	0.0	0.0	-0.1	0.2	-0.1	0.0	0.1
Indifference point function log k	0.0	0.0	0.1	-0.3	-0.1	-0.0	0.0	0.0	0.0	-0.1	0.2	-0.1	0.0	0.1
Patch foraging total patch changes 0 sec	1.9	3.1	4.7	1.7	1.6	1.6	-1.6	-1.8	-1.8	-1.6	1.4	2.0	1.8	-2.2
Patch foraging total patch changes 12 sec	1.1	1.5	2.5	1.2	1.1	1.1	-1.1	-1.3	-1.2	-1.1	0.9	1.6	1.2	-1.4
Patch foraging total patch changes 18 sec	2.0	2.6	3.7	1.7	1.6	1.5	-1.5	-1.6	-1.6	-1.4	1.2	1.9	1.5	-1.9
Patch foraging total patch changes 24 sec	0.7	0.9	1.7	-0.9	-1.1	-1.0	1.0	0.9	0.9	1.1	-1.3	-0.6	-0.9	0.4
Patch foraging total patch changes 6 sec	2.2	3.3	5.0	1.5	1.7	1.7	-1.7	-1.9	-1.9	-1.7	1.5	2.1	1.8	-2.2
Patch foraging time to switch 0 sec	0.5	0.8	1.0	-0.6	-0.9	-1.0	1.0	0.9	0.9	0.9	-0.8	-0.9	-0.8	1.0
Patch foraging water rate 0 sec	2.0	3.2	4.2	1.5	1.7	1.9	-1.9	-1.8	-1.9	-1.7	1.6	1.9	1.8	-2.1
Patch foraging water rate 12 sec	0.1	0.2	0.3	-0.0	0.3	0.4	-0.4	-0.4	-0.4	-0.4	0.4	0.5	0.4	-0.5
Patch foraging water rate 18 sec	0.1	0.1	0.3	-0.3	-0.4	-0.4	0.4	0.2	0.3	0.0	0.2	-0.5	-0.0	0.3
Patch foraging water rate 24 sec	0.1	0.1	0.2	0.2	0.4	0.3	-0.3	-0.3	-0.3	-0.2	0.3	0.2	0.2	-0.3
Patch foraging water rate 6 sec	0.3	0.5	0.8	0.5	0.7	0.7	-0.7	-0.7	-0.7	-0.8	0.9	0.6	0.7	-0.6
Seeking ratio, delayed vs. immediate footshock	0.3	0.4	0.8	-0.2	-0.7	-0.7	0.7	0.6	0.6	0.4	-0.2	-0.8	-0.4	0.9
Distance traveled before self-admin	0.2	0.2	0.4	0.6	0.3	0.4	-0.4	-0.4	-0.4	-0.3	0.3	0.4	0.4	-0.5
Distance traveled after self-admin	0.2	0.2	0.3	0.4	0.3	0.2	-0.2	-0.5	-0.5	-0.5	0.6	0.4	0.6	-0.5
Extensor digitorum longus weight	3.4	13.2	13.9	3.5	3.7	3.5	-3.5	-3.7	-3.7	-3.7	3.6	3.7	3.7	-3.7
Bone: elastic displacement	0.8	0.9	1.3	-0.9	-1.0	-1.1	1.1	0.9	0.9	0.9	-0.9	-0.9	-0.9	0.9
Bone: elastic work	0.0	0.0	0.1	0.1	-0.0	-0.3	0.3	-0.1	-0.1	-0.2	0.3	0.0	0.2	-0.1
Bone: endosteal estimation	0.0	0.1	0.3	0.5	0.3	0.2	-0.2	-0.3	-0.3	-0.3	0.3	0.3	0.3	-0.3
Bone: endosteal perimeter	0.6	1.2	1.7	1.3	1.1	1.0	-1.0	-1.1	-1.0	-1.1	1.2	1.0	1.1	-0.9
Epididymis fat weight	0.4	0.8	1.1	-1.0	-1.0	-0.9	0.9	0.9	0.9	0.9	-0.9	-0.8	-0.9	0.8
Delta time in closed arm before/after self-admin	7.0	6.7	7.1	-2.4	-2.6	-2.7	2.7	2.7	2.7	2.6	-2.5	-2.6	-2.6	2.7
Delta time in open arm before/after self-admin	8.1	7.8	9.1	3.0	2.7	2.8	-2.8	-2.9	-2.8	-2.8	2.7	2.7	2.8	-2.8
Diff in mean of infusions in LGA sessions	0.3	0.3	0.6	-0.3	-0.7	-0.7	0.7	0.5	0.6	0.5	-0.4	-0.5	-0.4	0.5
Delay discount exponential model param	3.2	3.4	4.3	-2.0	-1.7	-1.7	1.7	1.8	1.8	2.0	-2.1	-1.7	-1.9	1.7
Extinction: sum of active levers before priming	0.6	0.6	0.7	0.7	0.6	0.7	-0.7	-0.8	-0.8	-0.8	0.8	0.8	0.8	-0.8
Active lever presses in extinction session 6	0.1	0.1	0.3	0.6	0.1	0.1	-0.1	-0.2	-0.2	-0.3	0.3	0.2	0.2	-0.1
Bone: final force	0.4	0.6	1.0	0.7	0.7	0.6	-0.6	-0.8	-0.8	-0.8	0.8	1.0	0.9	-1.0
Bone: final moment	0.5	0.9	1.2	0.8	0.8	0.7	-0.7	-1.0	-1.0	-1.0	0.9	1.1	1.0	-1.1
Food consumed during 24 hour testing period	2.3	2.7	3.8	1.6	1.9	1.7	-1.7	-1.6	-1.7	-1.5	1.4	1.7	1.5	-1.7
Glucose	18.3	27.6	34.5	5.7	5.9	5.9	-5.9	-5.1	-5.2	-4.6	4.2	5.3	4.6	-5.2
Heart weight	0.2	0.3	0.9	-0.9	-0.4	-0.4	0.4	0.6	0.5	0.7	-0.8	-0.2	-0.7	0.3
Delay discount hyperbolic model param	3.3	3.5	4.5	-2.0	-1.8	-1.8	1.8	1.9	1.9	2.0	-2.1	-1.7	-2.0	1.7
Intermittent access intake day 1-15 change	0.4	0.4	0.6	0.4	0.6	0.7	-0.7	-0.6	-0.6	-0.5	0.4	0.8	0.5	-0.8
Intermittent access intake escalation	0.2	0.2	0.3	0.2	0.3	0.5	-0.5	-0.4	-0.4	-0.3	0.2	0.6	0.3	-0.6
Intermittent access intake escalation 2	0.1	0.1	0.3	0.1	0.3	0.4	-0.4	-0.3	-0.3	-0.2	0.0	0.5	0.2	-0.5
Intermitt. access day 1 inactive lever presses	0.5	0.6	1.1	-1.0	-0.6	-0.8	0.8	0.8	0.8	0.7	-0.5	-0.8	-0.7	0.7
Intermitt. access day 15 inactive lever presses	1.2	1.3	1.7	0.9	1.3	1.1	-1.1	-1.2	-1.2	-1.2	1.1	1.0	1.2	-1.2
Intermitt. access escalation Index	0.2	0.2	0.3	0.2	0.3	0.4	-0.4	-0.4	-0.4	-0.3	0.2	0.5	0.4	-0.5
Intermittent access day 1 total infusions	0.2	0.3	0.4	-0.0	-0.5	-0.6	0.6	0.5	0.5	0.5	-0.4	-0.6	-0.5	0.6
Intermittent access day 15 total infusions	0.1	0.1	0.3	0.5	0.3	0.3	-0.3	-0.4	-0.4	-0.3	0.3	0.4	0.3	-0.4
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.3	0.5	0.2	0.2	-0.2	-0.2	-0.2	-0.1	0.0	0.2	0.2	-0.3
Intermittent access total infusions	0.0	0.0	0.1	0.4	0.0	0.0	-0.0	-0.1	-0.1	-0.1	0.0	0.0	0.1	-0.1
Intermittent access day 1 locomotion	1.0	1.0	1.3	-0.8	-1.1	-1.1	1.1	1.0	1.0	0.9	-0.8	-1.0	-1.0	1.1
Intermittent access day 15 total locomotion	0.2	0.2	0.4	0.6	0.3	0.4	-0.4	-0.4	-0.5	-0.5	0.6	0.5	0.5	-0.4
Intermittent access total locomotion	0.2	0.2	0.4	0.6	0.3	0.3	-0.3	-0.5	-0.5	-0.5	0.6	0.4	0.5	-0.4
Intermittent access standard deviation	1.4	1.4	2.2	-1.3	-1.1	-1.1	1.1	1.2	1.2	1.3	-1.5	-1.1	-1.3	1.0
Left kidney weight	0.0	0.1	0.2	-0.4	-0.2	-0.4	0.4	0.3	0.3	0.2	-0.0	-0.4	-0.2	0.3
Right kidney weight	1.0	2.7	3.4	-1.7	-1.7	-1.9	1.9	1.6	1.7	1.5	-1.3	-1.7	-1.4	1.7
Cocaine induced anxiety	3.3	3.8	4.9	1.7	1.9	1.9	-1.9	-2.0	-2.0	-2.0	2.0	2.2	2.0	-2.0
Post-drug Anxiety	1.2	1.3	1.8	0.9	1.2	1.2	-1.2	-1.1	-1.1	-1.0	1.0	1.3	1.0	-1.2
Baseline Anxiety	0.2	0.2	0.4	-0.4	-0.3	-0.3	0.3	0.5	0.5	0.5	-0.5	-0.6	-0.6	0.5
Tail length	1.2	3.5	4.4	1.9	1.8	1.4	-1.4	-1.9	-1.9	-2.0	2.1	1.9	2.1	-2.1
Length with tail	2.0	7.2	8.5	2.8	2.7	2.4	-2.4	-2.7	-2.6	-2.8	2.9	2.6	2.8	-2.7
Length without tail	1.3	2.8	3.5	1.9	1.8	1.7	-1.7	-1.6	-1.6	-1.7	1.7	1.6	1.6	-1.4
Times rat made contact with spout	0.2	0.2	0.3	0.3	0.6	0.6	-0.6	-0.1	-0.1	0.2	-0.5	0.5	-0.2	-0.6
Lifetime Intake	0.0	0.0	0.2	0.4	0.1	0.0	-0.0	-0.1	-0.1	-0.1	0.1	0.0	0.1	-0.1
Liver weight, left	2.4	3.8	4.7	-1.6	-2.0	-2.1	2.1	2.0	2.0	1.8	-1.7	-2.1	-1.8	2.2
Liver weight, right	4.0	6.7	8.2	-2.3	-2.7	-2.8	2.8	2.6	2.7	2.4	-2.0	-2.8	-2.5	2.9
Locomotor activity	0.5	0.8	1.9	1.4	1.1	0.9	-0.9	-0.9	-0.9	-0.7	0.5	0.7	0.7	-0.6
Locomotor testing distance	0.1	0.2	0.3	0.6	0.5	0.3	-0.3	-0.4	-0.4	-0.4	0.4	0.3	0.5	-0.2
Locomotor testing rearing	1.9	2.9	3.9	1.8	2.0	1.8	-1.8	-1.7	-1.7	-1.6	1.5	1.8	1.6	-1.6
Locomotion in novel chamber	5.1	6.3	7.1	-2.4	-2.4	-2.4	2.4	2.6	2.6	2.6	-2.6	-2.4	-2.7	2.5
Locomotion in novel chamber post-restriction	2.9	3.5	3.9	-1.9	-1.8	-1.8	1.8	2.0	1.9	1.9	-1.9	-1.7	-2.0	1.9
Fecal boli incidents, locomotor time 1	0.3	0.3	0.7	-0.5	-0.5	-0.5	0.5	0.5	0.5	0.4	-0.4	-0.8	-0.5	0.7
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.2	0.4	0.4	-0.4	-0.2	-0.3	-0.1	-0.0	0.3	0.2	-0.3
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.5	0.1	0.1	0.1	-0.1	0.4	0.4	0.5	-0.5	-0.7	-0.6	0.6
Bouts of movement, locomotor time 1	0.4	0.5	0.8	0.9	0.8	0.8	-0.8	-0.7	-0.7	-0.5	0.4	0.5	0.6	-0.5
Total resting periods, locomotor time 1	0.2	0.2	0.3	0.5	0.6	0.6	-0.6	-0.4	-0.4	-0.3	0.2	0.2	0.3	-0.3
Rest time, locomotor task time 1	0.0	0.1	0.1	0.2	0.4	0.4	-0.4	-0.1	-0.1	0.0	-0.0	-0.2	-0.1	0.2
Distance moved, locomotor task time 1	0.2	0.3	0.4	0.5	0.3	0.3	-0.3	-0.5	-0.5	-0.6	0.7	0.6	0.6	-0.6
Vertical activity count, locomotor time 1	0.1	0.1	0.2	0.4	0.0	0.0	-0.0	-0.2	-0.2	-0.3	0.3	0.4	0.3	-0.3
Time >=10cm from walls, locomotor time 2	0.5	0.5	1.3	0.1	-0.4	-0.4	0.4	0.8	0.8	0.7	-0.6	-1.1	-0.8	1.1
Bouts of movement, locomotor time 2	0.1	0.2	0.5	-0.3	-0.2	-0.2	0.2	-0.3	-0.2	-0.5	0.7	0.3	0.6	-0.4
Total resting periods, locomotor time 2	0.2	0.2	0.6	-0.3	-0.0	-0.0	0.0	-0.4	-0.3	-0.6	0.7	0.4	0.7	-0.5
Rest time, locomotor task time 2	0.0	0.0	0.1	-0.3	0.0	0.0	-0.0	0.1	0.1	0.2	-0.3	-0.1	-0.2	0.1
Distance moved, locomotor task time 2	0.1	0.1	0.2	0.1	-0.3	-0.3	0.3	0.4	0.3	0.3	-0.3	-0.5	-0.4	0.5
Vertical activity count, locomotor time 2	0.2	0.2	0.5	0.2	-0.3	-0.3	0.3	0.5	0.4	0.5	-0.4	-0.6	-0.6	0.7
Light reinforcement 1	0.1	0.1	0.3	0.1	0.3	0.3	-0.3	-0.4	-0.4	-0.5	0.5	0.4	0.4	-0.3
Light reinforcement 2	0.0	0.1	0.3	0.3	0.1	0.1	-0.1	-0.1	-0.1	-0.3	0.5	-0.2	0.2	0.1
Bone: marrow area	0.0	0.0	0.2	0.4	0.2	0.1	-0.1	-0.2	-0.2	-0.2	0.1	0.2	0.2	-0.2
Bone: maximum diameter	5.1	9.4	10.5	3.2	3.2	3.2	-3.2	-3.0	-3.0	-3.0	2.9	3.0	2.9	-3.0
Bone: maximum force	0.3	0.5	0.7	0.6	0.7	0.6	-0.6	-0.7	-0.7	-0.7	0.7	0.8	0.8	-0.8
Bone: maximum moment	0.4	0.7	0.9	0.8	0.8	0.7	-0.7	-0.9	-0.9	-0.9	0.9	0.9	0.9	-1.0
Mean time between licks in bursts	0.6	0.8	1.4	1.0	1.2	1.0	-1.0	-0.8	-0.8	-0.6	0.5	1.1	0.6	-1.0
Mean num. licks in bursts	1.9	2.3	3.8	-1.4	-1.4	-1.3	1.3	1.6	1.5	1.8	-1.9	-1.2	-1.7	1.2
Cd content in liver	0.2	0.3	0.4	-0.6	-0.5	-0.5	0.5	0.5	0.5	0.5	-0.4	-0.5	-0.4	0.6
Co content in liver	0.0	0.0	0.1	-0.2	0.0	0.1	-0.1	-0.2	-0.2	-0.2	0.2	0.1	0.3	-0.3
Cu content in liver	0.5	0.7	1.0	0.7	1.0	0.9	-0.9	-0.8	-0.8	-0.7	0.7	0.9	0.7	-0.7
Fe content in liver	0.1	0.2	0.3	-0.4	-0.4	-0.4	0.4	0.5	0.4	0.5	-0.5	-0.1	-0.5	0.2
K content in liver	0.5	0.5	1.0	0.5	0.6	0.8	-0.8	-0.7	-0.6	-0.8	1.0	0.6	0.7	-0.5
Mg content in liver	0.5	0.5	0.9	0.4	0.7	0.9	-0.9	-0.6	-0.7	-0.7	0.7	0.7	0.6	-0.7
Mn content in liver	0.1	0.1	0.4	-0.1	0.0	0.3	-0.3	-0.3	-0.3	-0.5	0.6	0.2	0.4	-0.2
Na content in liver	4.3	4.5	5.0	2.2	2.2	2.2	-2.2	-2.1	-2.1	-2.1	2.0	2.1	2.0	-2.1
Rb content in liver	2.9	3.6	4.1	1.9	2.0	2.0	-2.0	-1.9	-1.9	-1.9	1.9	1.7	1.9	-1.7
Se content in liver	1.7	2.1	2.6	1.2	1.2	1.5	-1.5	-1.5	-1.5	-1.6	1.6	1.5	1.5	-1.4
Sr content in liver	2.1	1.9	2.2	1.5	1.5	1.4	-1.4	-1.4	-1.3	-1.4	1.3	1.4	1.4	-1.4
Zn content in liver	0.4	0.4	0.7	0.5	0.8	0.8	-0.8	-0.6	-0.6	-0.7	0.8	0.5	0.7	-0.5
Bone: minimum diameter	0.0	0.0	0.0	0.0	-0.1	-0.1	0.1	0.1	0.1	-0.0	0.1	-0.1	-0.0	0.0
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.4	-0.4	-0.4	0.4	0.3	0.3	0.3	-0.3	0.2	-0.2	0.1
Time in novel zone, hab. session 1	0.2	0.2	0.5	0.7	0.6	0.6	-0.6	-0.5	-0.5	-0.4	0.4	0.1	0.4	-0.3
Total zone transitions, hab. session 1	0.0	0.0	0.1	-0.0	0.4	0.3	-0.3	-0.1	-0.2	-0.1	0.1	0.2	0.1	-0.4
Total locomotion distance, hab. session 1	0.1	0.2	0.3	0.3	0.5	0.5	-0.5	-0.3	-0.3	-0.4	0.6	0.5	0.3	-0.4
Locomotion velocity, hab. session 1	0.0	0.0	0.1	0.1	0.3	0.3	-0.3	-0.1	-0.1	-0.1	0.2	0.2	0.0	-0.2
Time in familiar zone, hab. session 2	1.9	2.0	2.8	-1.2	-1.6	-1.7	1.7	1.4	1.4	1.4	-1.4	-1.1	-1.3	1.3
Time in novel zone, hab. session 2	2.8	2.8	3.9	1.4	1.9	2.0	-2.0	-1.6	-1.7	-1.6	1.5	1.4	1.5	-1.6
Total zone transitions, hab. session 2	1.1	1.4	1.7	0.8	1.2	1.2	-1.2	-1.1	-1.1	-1.2	1.3	1.2	1.1	-1.3
Total locomotion distance, hab. session 2	1.4	1.8	2.2	0.9	1.4	1.4	-1.4	-1.3	-1.3	-1.4	1.5	1.5	1.3	-1.5
Locomotion velocity, hab. session 2	1.6	2.2	2.8	1.1	1.5	1.5	-1.5	-1.4	-1.4	-1.5	1.7	1.5	1.4	-1.5
Novel to familiar place preference ratio	0.6	0.6	1.4	1.2	1.0	1.0	-1.0	-0.7	-0.7	-0.6	0.5	0.5	0.5	-0.6
Novelty place preference	0.7	0.7	1.5	1.2	1.1	1.1	-1.1	-0.7	-0.8	-0.6	0.5	0.5	0.5	-0.6
Time in novel zone, NPP test	0.7	0.7	1.4	1.2	1.1	1.1	-1.1	-0.7	-0.8	-0.6	0.5	0.5	0.5	-0.6
Total zone transitions, NPP test	0.2	0.3	1.0	-1.0	-0.6	-0.6	0.6	0.6	0.6	0.4	-0.3	-0.4	-0.5	0.3
Total locomotion distance, NPP test	0.0	0.0	0.2	-0.5	-0.1	-0.1	0.1	0.1	0.2	-0.0	0.2	-0.0	-0.0	-0.1
Locomotion velocity, NPP test	0.0	0.0	0.2	-0.2	0.1	0.1	-0.1	-0.1	-0.1	-0.3	0.5	0.2	0.2	-0.2
Intraocular pressure	0.4	0.5	0.8	0.7	0.8	0.9	-0.9	-0.7	-0.7	-0.7	0.6	0.6	0.7	-0.6
Delta distance traveled before/after self-admin	0.2	0.2	0.4	-0.6	-0.4	-0.5	0.5	0.4	0.4	0.3	-0.2	-0.6	-0.3	0.5
Delta ambulatory time before/after self-admin	0.4	0.4	0.8	-0.9	-0.6	-0.7	0.7	0.6	0.6	0.5	-0.4	-0.7	-0.5	0.6
Parametrial fat weight	2.0	3.9	5.3	2.3	1.8	1.9	-1.9	-2.0	-2.0	-1.9	1.9	2.1	1.9	-2.0
Pavlov. Cond. lever latency	0.4	0.5	1.1	1.0	0.8	0.8	-0.8	-0.7	-0.7	-0.6	0.5	0.7	0.6	-0.6
Pavlov. Cond. magazine entry latency	1.9	2.4	3.6	-1.9	-1.6	-1.6	1.6	1.5	1.5	1.5	-1.5	-1.5	-1.5	1.4
Pavlov. Cond. change in total contacts	1.4	1.5	2.1	0.7	1.0	1.1	-1.1	-1.2	-1.2	-1.3	1.3	1.4	1.3	-1.4
Pavlov. Cond. index score	1.9	2.4	4.1	-2.0	-1.7	-1.6	1.6	1.5	1.5	1.4	-1.3	-1.5	-1.4	1.4
Pavlov. Cond. latency score	1.5	2.0	3.2	-1.8	-1.5	-1.5	1.5	1.4	1.4	1.3	-1.2	-1.3	-1.3	1.2
Pavlov. Cond. lever contacts	0.6	0.7	1.9	-1.4	-1.0	-0.9	0.9	0.8	0.8	0.7	-0.6	-0.6	-0.6	0.5
Pavlov. Cond. magazine entry number	1.9	2.4	4.2	2.1	1.7	1.6	-1.6	-1.5	-1.5	-1.5	1.5	1.4	1.4	-1.3
Pavlov. Cond. intertrial magazine entries	0.3	0.3	0.9	0.7	0.5	0.4	-0.4	-0.5	-0.5	-0.7	0.9	0.4	0.7	-0.3
Pavlov. Cond. lever-magazine prob. diff.	2.3	2.8	4.8	-2.2	-1.8	-1.7	1.7	1.6	1.6	1.5	-1.4	-1.6	-1.5	1.5
Pavlov. Cond. response bias	0.8	0.9	2.8	-1.7	-1.1	-1.0	1.0	0.9	0.9	0.8	-0.7	-0.8	-0.8	0.7
Pavlov. Cond. lever latency	3.6	4.8	6.1	2.3	2.1	2.1	-2.1	-2.2	-2.2	-2.3	2.5	2.1	2.3	-2.0
Pavlov. Cond. magazine entry latency	0.0	0.0	0.1	-0.3	0.2	0.2	-0.2	0.1	0.1	0.1	-0.1	-0.2	-0.2	0.1
Pavlov. Cond. change in total contacts	0.2	0.3	0.5	-0.5	-0.3	-0.5	0.5	0.6	0.6	0.6	-0.7	-0.7	-0.6	0.6
Pavlov. Cond. index score	1.3	1.7	2.0	-1.4	-1.1	-1.1	1.1	1.3	1.3	1.4	-1.4	-1.4	-1.4	1.3
Pavlov. Cond. latency score	1.3	1.7	2.1	-1.4	-1.1	-1.2	1.2	1.3	1.3	1.3	-1.4	-1.4	-1.3	1.3
Pavlov. Cond. lever contacts	3.2	4.3	5.4	-2.0	-2.0	-2.0	2.0	2.1	2.0	2.2	-2.3	-2.1	-2.2	1.9
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	0.2	-0.2	-0.2	0.2	-0.1	-0.0	-0.2	0.3	0.1	0.2	0.0
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.1	0.0	-0.2	-0.1	0.1	-0.1	-0.1	-0.2	0.2	0.3	0.2	-0.1
Pavlov. Cond. lever-magazine prob. diff.	1.3	1.6	2.0	-1.4	-1.0	-1.1	1.1	1.3	1.3	1.4	-1.4	-1.4	-1.4	1.2
Pavlov. Cond. response bias	1.3	1.7	2.6	-1.2	-1.2	-1.2	1.2	1.3	1.3	1.5	-1.6	-1.3	-1.4	1.2
Time in closed arm before self-admin	0.4	0.4	0.7	0.8	0.6	0.6	-0.6	-0.7	-0.6	-0.6	0.6	0.7	0.7	-0.6
Time in closed arm after self-admin	2.1	2.1	2.4	-1.3	-1.5	-1.5	1.5	1.5	1.5	1.5	-1.4	-1.4	-1.4	1.4
Time in open arm before self-admin	2.6	2.8	3.3	-1.8	-1.7	-1.6	1.6	1.7	1.7	1.7	-1.7	-1.7	-1.7	1.6
Time in open arm after self-admin	0.2	0.2	0.3	0.6	0.3	0.4	-0.4	-0.4	-0.4	-0.4	0.4	0.3	0.4	-0.4
Bone: periosteal estimation	0.9	1.9	2.5	1.6	1.5	1.3	-1.3	-1.4	-1.4	-1.4	1.4	1.3	1.3	-1.3
Bone: periosteal perimeter	1.8	3.0	3.7	1.9	1.9	1.7	-1.7	-1.7	-1.7	-1.8	1.9	1.6	1.7	-1.6
Bone: post-yield work	0.2	0.3	0.4	0.5	0.6	0.7	-0.7	-0.5	-0.5	-0.5	0.5	0.5	0.4	-0.3
Progressive ratio test 1 active lever presses	0.0	0.0	0.1	0.3	-0.0	-0.1	0.1	0.0	-0.0	-0.0	0.0	-0.1	0.0	0.1
Progressive ratio test 1 breakpoint	0.2	0.2	0.2	-0.1	-0.4	-0.5	0.5	0.4	0.4	0.4	-0.4	-0.5	-0.4	0.5
Progressive ratio test 1 inactive lever presses	2.5	2.7	3.8	1.6	1.7	1.5	-1.5	-1.7	-1.6	-1.8	2.0	1.5	1.8	-1.6
Progressive ratio test 2 active lever presses	0.0	0.0	0.1	0.3	0.0	-0.0	0.0	-0.0	-0.0	0.0	-0.1	0.0	-0.0	-0.0
Progressive ratio test 2 breakpoint	0.0	0.0	0.1	0.3	0.1	0.1	-0.1	-0.1	-0.1	-0.0	-0.0	0.1	0.0	-0.1
Progressive ratio test 2 inactive lever presses	0.6	0.7	0.8	0.9	0.9	0.7	-0.7	-0.8	-0.8	-0.9	0.9	0.7	0.8	-0.7
Incentive Sensitization - Responses	0.0	0.0	0.1	0.3	0.3	0.2	-0.2	-0.1	-0.1	0.0	-0.1	0.1	-0.0	-0.1
Incentive Sensitization - Breakpoint	0.0	0.0	0.0	0.2	0.2	0.1	-0.1	0.0	0.0	0.1	-0.2	0.1	-0.1	0.0
Sum of active levers in priming session hrs 5-6	1.2	1.1	1.4	0.7	1.0	1.0	-1.0	-1.1	-1.1	-1.1	1.2	1.2	1.1	-1.1
Progressive ratio	0.2	0.2	0.4	-0.1	-0.6	-0.6	0.6	0.4	0.4	0.4	-0.3	-0.2	-0.4	0.4
Food seeking constrained by brief footshock	1.8	2.3	3.4	1.5	1.3	1.3	-1.3	-1.5	-1.5	-1.7	1.8	1.6	1.5	-1.5
Seeking ratio, punishment vs. effort	1.2	1.5	2.0	0.9	1.3	1.3	-1.3	-1.2	-1.2	-1.3	1.4	1.0	1.3	-1.1
Retroperitoneal fat weight	0.0	0.0	0.1	-0.1	-0.3	-0.3	0.3	-0.0	-0.0	-0.1	0.2	-0.0	0.2	-0.1
Reaction time number correct	0.1	0.1	0.2	0.1	0.3	0.5	-0.5	-0.3	-0.3	-0.2	0.1	0.2	0.2	-0.3
Reaction time mean minus median	1.6	2.1	3.2	-1.3	-1.2	-1.2	1.2	1.5	1.5	1.6	-1.8	-1.3	-1.6	1.4
Reaction time mean minus median AUC	1.4	1.8	2.7	-1.2	-1.1	-1.1	1.1	1.4	1.4	1.5	-1.6	-1.2	-1.5	1.3
Reaction time num false alarms	0.3	0.4	0.8	0.0	0.2	0.4	-0.4	-0.7	-0.7	-0.8	0.9	0.8	0.9	-0.8
Reaction time num false alarms AUC	0.2	0.3	0.8	-0.1	0.0	0.2	-0.2	-0.6	-0.6	-0.8	0.9	0.6	0.8	-0.7
Reaction time trials correct on left	0.1	0.1	0.2	0.1	0.3	0.5	-0.5	-0.3	-0.3	-0.2	0.1	0.2	0.2	-0.3
Reaction time trials on left	0.0	0.1	0.2	0.0	0.3	0.4	-0.4	-0.2	-0.3	-0.1	0.1	0.1	0.2	-0.3
Reaction time mean	0.8	1.1	1.3	-0.9	-1.1	-1.1	1.1	1.1	1.1	1.1	-1.1	-1.1	-1.0	1.1
Reaction time mean AUC	1.4	1.9	2.2	-1.2	-1.4	-1.4	1.4	1.4	1.4	1.3	-1.3	-1.5	-1.3	1.4
Median of all reaction times	0.4	0.6	0.8	-0.6	-0.8	-0.9	0.9	0.7	0.8	0.7	-0.6	-0.9	-0.6	0.8
Reaction time omissions	1.3	1.8	2.3	-1.5	-1.5	-1.4	1.4	1.2	1.3	1.2	-1.3	-1.3	-1.1	1.2
Reaction time false alarm rate	0.2	0.2	0.7	-0.1	-0.1	0.0	-0.0	-0.5	-0.4	-0.7	0.8	0.5	0.7	-0.5
Reaction time premature initiation rate	2.9	3.9	5.1	-2.3	-2.0	-1.9	1.9	2.0	2.0	1.9	-1.8	-1.9	-2.0	2.0
Reaction time premature initiations	1.4	2.0	3.1	-1.8	-1.4	-1.3	1.3	1.4	1.4	1.4	-1.4	-1.4	-1.4	1.4
Std. dev. reaction times	1.3	1.9	2.5	-1.2	-1.3	-1.4	1.4	1.4	1.4	1.5	-1.6	-1.3	-1.4	1.3
Reaction time trials completed	0.0	0.1	0.2	0.0	0.3	0.4	-0.4	-0.2	-0.3	-0.1	0.1	0.1	0.2	-0.3
Reaction time trials AUC	0.1	0.1	0.3	0.2	0.4	0.5	-0.5	-0.3	-0.4	-0.3	0.2	0.2	0.3	-0.4
Run reversals in cocaine runway, females	0.5	0.5	0.9	-0.9	-0.9	-0.9	0.9	0.7	0.7	0.6	-0.5	-0.5	-0.6	0.5
Run reversals in cocaine runway, males	0.4	0.4	0.5	0.7	0.7	0.7	-0.7	-0.6	-0.6	-0.5	0.5	0.4	0.5	-0.4
Latency to leave start box in cocaine runway	0.1	0.1	0.3	0.1	-0.2	-0.1	0.1	-0.3	-0.2	-0.4	0.4	0.4	0.5	-0.5
Latency to leave start box in cocaine runway, F	0.6	0.6	0.9	0.6	0.6	0.6	-0.6	-0.8	-0.7	-0.8	0.9	0.9	0.9	-0.9
Latency to leave start box in cocaine runway, M	0.7	0.7	1.4	-0.7	-1.2	-1.1	1.1	0.7	0.8	0.7	-0.7	-0.7	-0.6	0.5
Std. dev. time between licks in bursts	0.0	0.0	0.1	-0.0	0.1	0.1	-0.1	-0.1	-0.1	-0.0	-0.0	0.3	0.1	-0.3
Total sessions with >9 infusions	0.0	0.0	0.0	-0.1	-0.2	-0.2	0.2	0.2	0.2	0.2	-0.2	-0.2	-0.2	0.2
Short access day 1 total inactive lever presses	3.1	3.5	4.3	2.1	1.6	1.6	-1.6	-1.9	-1.9	-2.0	2.1	1.8	2.0	-1.8
Short access day 10 total inactive lever presses	0.1	0.2	0.5	-0.7	-0.4	-0.4	0.4	0.4	0.4	0.3	-0.2	-0.3	-0.3	0.2
Short access day 1 total infusions	0.4	0.4	0.6	-0.4	-0.5	-0.7	0.7	0.6	0.7	0.6	-0.5	-0.8	-0.6	0.8
Short access day 10 total infusions	0.4	0.4	0.7	-0.2	-0.7	-0.8	0.8	0.6	0.7	0.6	-0.6	-0.8	-0.6	0.7
Short access total infusions	0.5	0.5	0.7	-0.4	-0.7	-0.8	0.8	0.7	0.7	0.7	-0.7	-0.8	-0.7	0.8
Short access day 1 locomotion	1.7	1.8	2.0	-1.3	-1.4	-1.4	1.4	1.4	1.4	1.3	-1.2	-1.4	-1.3	1.4
Short access day 10 total locomotion	0.6	0.7	0.9	-0.7	-0.9	-1.0	1.0	0.9	0.8	0.7	-0.6	-0.9	-0.8	0.9
Short access total locomotion	3.8	3.9	4.3	-1.8	-2.0	-2.1	2.1	2.0	2.0	1.9	-1.8	-2.0	-2.0	2.0
One hour access (0.3 mA shock)	0.0	0.0	0.1	0.1	-0.3	-0.3	0.3	0.1	0.1	0.1	-0.1	0.0	-0.1	-0.0
Compulsive drug intake	2.4	2.4	3.1	-1.8	-1.5	-1.7	1.7	1.6	1.6	1.6	-1.6	-1.3	-1.6	1.3
One hour access (shock baseline)	0.6	0.6	1.4	1.2	0.6	0.7	-0.7	-0.8	-0.8	-0.8	0.8	0.8	0.7	-0.8
Social response proportion	2.2	2.4	3.0	1.6	1.7	1.7	-1.7	-1.5	-1.5	-1.5	1.6	1.4	1.4	-1.4
Social responses	2.7	3.4	3.8	1.7	1.9	1.9	-1.9	-1.9	-1.9	-1.9	1.8	1.7	1.8	-1.8
Social time	0.3	0.4	0.6	0.5	0.5	0.5	-0.5	-0.7	-0.7	-0.7	0.7	0.6	0.7	-0.7
Soleus weight	0.6	1.8	2.7	1.6	1.3	1.1	-1.1	-1.3	-1.3	-1.5	1.6	1.2	1.5	-1.1
Bone: stiffness	0.0	0.0	0.0	0.0	0.1	0.0	-0.0	0.1	0.1	0.1	-0.2	-0.0	-0.2	0.0
Tibialis anterior weight	1.2	4.0	4.6	2.1	2.0	1.8	-1.8	-2.0	-2.0	-2.0	1.9	2.1	2.0	-2.1
Time to tail flick, vehicle, before self-admin	0.0	0.0	0.1	-0.2	-0.3	-0.2	0.2	0.1	0.1	-0.1	0.2	-0.0	0.0	0.2
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.1	-0.3	-0.1	-0.0	0.0	-0.1	-0.1	-0.3	0.4	0.1	0.3	-0.2
Time to tail flick, test, before self-admin	0.9	0.8	1.4	-0.7	-0.7	-0.7	0.7	0.9	0.9	1.0	-1.2	-1.0	-1.0	1.0
Time to tail flick, test, after self-admin	3.4	3.5	4.4	1.7	1.7	1.9	-1.9	-1.8	-1.8	-2.0	2.1	1.9	1.9	-1.8
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	0.1	0.0	-0.1	0.1	0.0	0.1	0.0	-0.0	-0.3	-0.0	0.1
Delta time to tail flick, test, before/after SA	2.9	2.6	3.4	1.3	1.4	1.6	-1.6	-1.6	-1.6	-1.7	1.9	1.8	1.7	-1.6
Tibia length	0.1	0.3	0.8	-0.3	-0.6	-0.9	0.9	0.4	0.5	0.3	-0.1	-0.4	-0.3	0.5
Ambulatory time before self-admin	0.5	0.5	0.7	0.8	0.6	0.6	-0.6	-0.7	-0.7	-0.7	0.7	0.7	0.7	-0.8
Ambulatory time after self-admin	0.2	0.3	0.4	0.5	0.4	0.3	-0.3	-0.5	-0.5	-0.6	0.7	0.5	0.6	-0.6
Bone: tissue strength	0.0	0.0	0.1	0.4	0.3	0.2	-0.2	-0.0	-0.0	0.2	-0.3	0.2	-0.1	-0.1
Total heroin consumption	0.1	0.1	0.2	0.5	0.1	0.2	-0.2	-0.3	-0.3	-0.3	0.2	0.0	0.3	-0.2
Bone: trabecular number	0.0	0.1	0.2	-0.4	-0.3	-0.3	0.3	0.2	0.2	0.2	-0.2	-0.1	-0.2	0.1
Bone: trabecular spacing	1.1	1.4	1.9	1.4	1.4	1.3	-1.3	-1.1	-1.1	-1.1	1.1	1.1	1.1	-1.0
Bone: trabecular thickness	1.1	1.3	2.1	-1.5	-1.3	-1.4	1.4	1.1	1.1	1.0	-0.8	-1.0	-0.9	0.9
Bone: trabecular tissue density	0.2	0.3	0.6	-0.4	-0.2	-0.3	0.3	0.6	0.5	0.7	-0.8	-0.5	-0.7	0.5
Water consumed over 24 hours	1.6	1.9	2.7	1.3	1.6	1.6	-1.6	-1.3	-1.3	-1.2	1.0	1.5	1.1	-1.5
Number of responses in last shaping day	0.0	0.0	0.1	-0.1	-0.3	-0.4	0.4	0.1	0.1	0.0	0.0	0.0	-0.0	0.1